Publications

  • 2017
  • Klimczak M, Czerwińska P, Mazurek S, Sozańska B, Biecek P, Mackiewicz A, Wiznerowicz M. TRIM28 epigenetic corepressor is indispensable for stable induced pluripotent stem cell formation. 2017. Stem Cell Research, 23 163–172. details
  • Tracz-Gaszewska Z, Klimczak M, Biecek P, Herok M, Kosinski M, Olszewski MB, Czerwińska P, Wiech M, Wiznerowicz M, Zylicz A, Zylicz M, Wawrzynow B. Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation. 2017. Oncotarget, Epub ahead of print . details
  • Pruszko M, Milano E, Forcato M, Donzelli S, Ganci F, Di Agostino S, De Panfilis S, Fazi F, Bates DO, Bicciato S, Zylicz M, Zylicz A, Blandino G, Fontemaggi G. The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1. 2017. EMBO Rep, pii: e201643370 [Epub ahead of print]. details
  • 2013
  • Żylicz M.. Biologia syntetyczna: jak powstawało życie na Ziemi?. 2013. Nauka, 7-18. details
  • 2012
  • Wiech M, Olszewski MB, Tracz-Gaszewska Z, Wawrzynow B, Zylicz M, Zylicz A. Molecular Mechanism of Mutant p53 Stabilization: The Role of HSP70 and MDM2. 2012. PLoS One, 7(12) e51426. details
  • 2011
  • Hageman J, van Waarde MA, Zylicz A, Walerych D, Kampinga HH. The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities. 2011. Biochem J, 435 127-142. details
  • 2010
  • Zubrienė A, Gutkowska M, Matulienė J, Chaleckis R, Michailovienė V, Voroncova A, Venclovas C, Zylicz A, Zylicz M, Matulis D. Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms. 2010. Biophys Chem, 152(1-3) 153-63. details
  • Kvardova V, Hrstka R, Walerych D, Muller P, Matoulkova E, Hruskova V, Stelclova D, Sova P, Vojtesek B. The new platinum(IV) derivative LA-12 shows stronger inhibitory effect on Hsp90 function compared to cisplatin. 2010. Mol Cancer, 9 147. details
  • Kirkegaard T, Roth AG, Petersen NH, Mahalka AK, Olsen OD, Moilanen I, Zylicz A, Knudsen J, Sandhoff K, Arenz C, Kinnunen PK, Nylandsted J, Jäättelä M. Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.. 2010. Nature, 463 549-53. details
  • Zurawska A, Urbanski J, Matuliene J, Baraniak J, Klejman MP, Filipek S, Matulis D, Bieganowski P. Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo.. 2010. Biochim Biophys Acta, 1803 575-83. details
  • Walerych D, Gutkowska M, Klejman MP, Wawrzynow B, Tracz Z, Wiech M, Zylicz M, Zylicz A. ATP binding to Hsp90 is sufficient for effective chaperoning of p53 protein.. 2010. J Biol Chem, 285 32020-8. details
  • 2009
  • Szymańska Z, Urbański J, Marciniak-Czochra A. Mathematical modelling of the influence of heat shock proteins on cancer invasion of tissue.. 2009. J Math Biol, 58 819-44. details
  • Walerych D, Olszewski MB, Gutkowska M, Helwak A, Zylicz M, Zylicz A. Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions.. 2009. Oncogene, 28 4284-94. details
  • Narayan V, Eckert M, Zylicz A, Zylicz M, Ball KL. Cooperative regulation of the interferon regulatory factor-1 tumor suppressor protein by core components of the molecular chaperone machinery. 2009. J Biol Chem, 284 25889-99. details
  • Wawrzynow B, Pettersson S, Zylicz A, Bramham J, Worrall E, Hupp TR, Ball KL. A function for the RING finger domain in the allosteric control of MDM2 conformation and activity.. 2009. J Biol Chem, 284 11517-30. details
  • Szymańska Z, Zylicz M. Mathematical modeling of heat shock protein synthesis in response to temperature change.. 2009. J Theor Biol, 259 562-9. details
  • 2008
  • Guranowski A, Wojdyła AM, Pietrowska-Borek M, Bieganowski P, Khurs EN, Cliff MJ, Blackburn GM, Błaziak D, Stec WJ. Fhit proteins can also recognize substrates other than dinucleoside polyphosphates.. 2008. FEBS Lett, 582 3152-8. details
  • Sbroggiò M, Ferretti R, Percivalle E, Gutkowska M, Zylicz A, Michowski W, Kuznicki J, Accornero F, Pacchioni B, Lanfranchi G, Hamm J, Turco E, Silengo L, Tarone G, Brancaccio M. The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1.. 2008. FEBS Lett, 582 1788-94. details
  • Stevens C, Pettersson S, Wawrzynow B, Wallace M, Ball K, Zylicz A, Hupp TR. ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1.. 2008. FEBS J, 275 4875-86. details
  • Zurawska A, Urbanski J, Bieganowski P. Hsp90n - An accidental product of a fortuitous chromosomal translocation rather than a regular Hsp90 family member of human proteome. 2008. Biochim Biophys Acta, 1784 1844-6. details
  • 2007
  • Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J,Filipek A. Hsp70 is a new target of Sgt1-an interaction modulated by S100A6. 2007. Biochem Biophys Res Commun, 357 1148-53. details
  • Schneider G, Nieznanski K, Kilanczyk E, Bieganowski P, Kuznicki J, Filipek A. CacyBP/SIP interacts with tubulin in neuroblastoma NB2a cells and induces formation of globular tubulin assemblies.. 2007. Biochim Biophys Acta, 1773 1628-36. details
  • Wawrzynow B, Zylicz A, Wallace M, Hupp T, Zylicz M. MDM2 chaperones the p53 tumor suppressor.. 2007. J Biol Chem, 282 32603-12. details
  • Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J, Filipek A. Hsp70 is a new target of Sgt1--an interaction modulated by S100A6. 2007. Biochem Biophys Res Commun, 357 1148-53. details
  • Issat T, Nowis D, Legat M, Makowski M, Klejman MP, Urbanski J, Skierski J, Koronkiewicz M, Stoklosa T, Brzezinska A, Bil J, Gietka J, Jakóbisiak M, Golab J. Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.. 2007. Int J Oncol, 30 1413-25. details
  • Schneider G, Nieznanski K, Kilanczyk E, Bieganowski P, Kuznicki J, Filipek A. CacyBP/SIP interacts with tubulin in neuroblastoma NB2a cells and induces formation of globular tubulin assemblies.. 2007. Biochim Biophys Acta, 1773 1628-36. details
  • Wawrzynow B, Zylicz A, Wallace M, Hupp T, Zylicz M. MDM2 chaperones the p53 tumor suppressor.. 2007. J Biol Chem, 282 32603-12. details
  • Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J, Filipek A. Hsp70 is a new target of Sgt1--an interaction modulated by S100A6.. 2007. Biochem Biophys Res Commun, 357 1148-53. details
  • Issat T, Nowis D, Legat M, Makowski M, Klejman MP, Urbanski J, Skierski J, Koronkiewicz M, Stoklosa T, Brzezinska A, Bil J, Gietka J, Jakóbisiak M, Golab J. Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.. 2007. Int J Oncol, 30 1413-25. details
  • 2006
  • Kudla G, Lipinski L, Caffin F, Helwak A, Zylicz M. High guanine and cytosine content increases mRNA levels in mammalian cells. 2006. PLoS Biol, 4 e180. details
  • Galazka G, Stasiolek M, Walczak A, Jurewicz A, Zylicz A, Brosnan CF, Raine CS, Selmaj KW. Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis.. 2006. J Immunol, 176 1588-99. details
  • Bieganowski P, Seidle HF, Wojcik M, Brenner C. Synthetic lethal and biochemical analyses of NAD and NADH kinases in Saccharomyces cerevisiae establish separation of cellular functions.. 2006. J Biol Chem, 281 22439-45. details
  • Wojcik M, Seidle HF, Bieganowski P, Brenner C. Glutamine-dependent NAD+ synthetase. How a two-domain, three-substrate enzyme avoids waste.. 2006. J Biol Chem, 281 33395-402. details
  • Kudla G, Lipinski L, Caffin F, Helwak A, Zylicz M. High guanine and cytosine content increases mRNA levels in mammalian cells. 2006. PLoS Biol, 4 e180. details
  • Galazka G, Stasiolek M, Walczak A, Jurewicz A, Zylicz A, Brosnan CF, Raine CS, Selmaj KW. Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis.. 2006. J Immunol, 176 1588-99. details
  • 2005
  • Klejman MP, Zhao X, van Schaik FM, Herr W, Timmers HT. Mutational analysis of BTAF1-TBP interaction: BTAF1 can rescue DNA-binding defective TBP mutants.. 2005. Nucleic Acids Res, 33 5426-36. details
  • Ilyushik E, Pryce DW, Walerych D, Riddell T, Wakeman JA, McInerny CJ, McFarlane RJ. Psc3 cohesin of Schizosaccharomyces pombe: cell cycle analysis and identification of three distinct isoforms.. 2005. Biol Chem, 386 613-21. details
  • Bucko-Justyna M, Lipinski L, Burgering BM, Trzeciak L. Characterization of testis-specific serine-threonine kinase 3 and its activation by phosphoinositide-dependent kinase-1-dependent signalling.. 2005. FEBS J, 272 6310-23. details
  • 2004
  • Mycko MP, Cwiklinska H, Szymanski J, Szymanska B, Kudla G, Kilianek L, Odyniec A, Brosnan CF, Selmaj KW. Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II.. 2004. J Immunol, 172 202-13. details
  • Walerych D, Kudla G, Gutkowska M, Wawrzynow B, Muller L, King FW, Helwak A, Boros J, Zylicz A, Zylicz M. Hsp90 chaperones wild-type p53 tumor suppressor protein.. 2004. J Biol Chem, 279 48836-45. details
  • Jassem J, Jassem E, Jakóbkiewicz-Banecka J, Rzyman W, Badzio A, Dziadziuszko R, Kobierska-Gulida G, Szymanowska A, Skrzypski M, Zylicz M. P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma.. 2004. Cancer, 100 1951-60. details
  • Dworakowska D, Jassem E, Jassem J, Peters B, Dziadziuszko R, Zylicz M, Jakóbkiewicz-Banecka J, Kobierska-Gulida G, Szymanowska A, Skokowski J, Roessner A, Schneider-Stock R. MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC).. 2004. Lung Cancer, 43 285-95. details
  • Mycko MP, Cwiklinska H, Szymanski J, Szymanska B, Kudla G, Kilianek L, Odyniec A, Brosnan CF, Selmaj KW. Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II.. 2004. J Immunol, 172 202-13. details
  • Kudla G, Helwak A, Lipinski L. Gene conversion and GC-content evolution in mammalian Hsp70.. 2004. Mol Biol Evol, 21 1438-44. details
  • Walerych D, Kudla G, Gutkowska M, Wawrzynow B, Muller L, King FW, Helwak A, Boros J, Zylicz A, Zylicz M. Hsp90 chaperones wild-type p53 tumor suppressor protein.. 2004. J Biol Chem, 279 48836-45. details
  • Müller L, Schaupp A, Walerych D, Wegele H, Buchner J. Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures.. 2004. J Biol Chem, 279 48846-54. details
  • Jassem J, Jassem E, Jakóbkiewicz-Banecka J, Rzyman W, Badzio A, Dziadziuszko R, Kobierska-Gulida G, Szymanowska A, Skrzypski M, Zylicz M. P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma.. 2004. Cancer, 100 1951-60. details
  • Dworakowska D, Jassem E, Jassem J, Peters B, Dziadziuszko R, Zylicz M, Jakóbkiewicz-Banecka J, Kobierska-Gulida G, Szymanowska A, Skokowski J, Roessner A, Schneider-Stock R. MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC).. 2004. Lung Cancer, 43 285-95. details
  • 2001
  • Kaczanowski R, Trzeciak L, Kucharczyk K. Multitemperature single-strand conformation polymorphism.. 2001. Electrophoresis, 22 3539-45. details
  • Zylicz M, Wawrzynow A. Insights into the function of Hsp70 chaperones.. 2001. IUBMB Life, 51 283-7. details
  • Zylicz M, King FW, Wawrzynow A. Hsp70 interactions with the p53 tumour suppressor protein. 2001. EMBO J, 20 4634-8. details
  • King FW, Wawrzynow A, Höhfeld J, Zylicz M. Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.. 2001. EMBO J, 20 6297-305. details
  • Jassem E, Nikliński J, Rosell R, Niklińska W, Jakóbkiewicz J, Monzo M, Chyczewski L, Kobierska G, Skokowski J, Zylicz M, Jassem J. Types and localisation of p53 gene mutations: a report on 332 non-small cell lung cancer patients.. 2001. Lung Cancer, 34 Suppl 2 S47-51. details
  • Genevaux P, Wawrzynow A, Zylicz M, Georgopoulos C, Kelley WL. DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction.. 2001. J Biol Chem, 276 7906-12. details
  • Banecki B, Wawrzynow A, Puzewicz J, Georgopoulos C, Zylicz M. Structure-function analysis of the zinc-binding region of the Clpx molecular chaperone.. 2001. J Biol Chem, 276 18843-8. details
  • Kaczanowski R, Trzeciak L, Kucharczyk K. Multitemperature single-strand conformation polymorphism.. 2001. Electrophoresis, 22 3539-45. details
  • Zylicz M, Wawrzynow A. Insights into the function of Hsp70 chaperones.. 2001. IUBMB Life, 51 283-7. details
  • Zylicz M, King FW, Wawrzynow A. Hsp70 interactions with the p53 tumour suppressor protein. 2001. EMBO J, 20 4634-8. details
  • King FW, Wawrzynow A, Höhfeld J, Zylicz M. Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.. 2001. EMBO J, 20 6297-305. details
  • Genevaux P, Wawrzynow A, Zylicz M, Georgopoulos C, Kelley WL. DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction.. 2001. J Biol Chem, 276 7906-12. details
  • Banecki B, Wawrzynow A, Puzewicz J, Georgopoulos C, Zylicz M. Structure-function analysis of the zinc-binding region of the Clpx molecular chaperone.. 2001. J Biol Chem, 276 18843-8. details