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Research  Grants, projects, programs |
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HEALTH-PROT "Proteins in Health and Desease" (Coordination and Support action), under negotiation |
J. Kuznicki |
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NEURO.GSK3 "GSK-3 in neuronal plasticity and neurodegeneration:
basic mechanisms and pre-clinical assessment" (Collaborative project), under negotiation |
J. Jaworski |
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SBMPs "Structural Biology of Membrane Proteins" (Marie Curie Initial Training Networks (ITN), under negotiation |
S. Filipek |
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EURASNET “European alternative splicing network of excellence” (LSHG-CT-2005-518238); 120,000 EUR; 2006-2010; IIMCB participation 2008-2010
MemProt “Structural studies of membrane proteases” (MTKD-CT-2006-042486); 626 800.51 EUR; 2006-2010
EndoTrack "Tracking the endocytic routes of polypeptide growth factor receptor complexes and their modulatory role on signalling” (019050 LSH 2006); 428,400 EUR; 2006-2010
DNA Enzymes "A multidisciplinary approach to the study of DNA enzymes down to the single molecule level" (MRTN-CT-2005-019566); 254,452 EUR; matching funds 606,181 PLN; 2005-2009
PROMEMORIA "From cell-cell recognition to memory formation. New strategies for the treatment of dysfunctional plasticity, learning and memory", (LSHM-CT-2005-512012); 478,000 EUR, matching funds 1,203,600 PLN; 2005-2009 |
J.M. Bujnicki
M. Bochtler
M. Miaczynska
J.M. Bujnicki
J. Kuznicki
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EUROGENTEST "Genetic Testing in Europe - Network for test development harmonization, validation and standardization of services" ( LSHB-CT-2004-512148), 30 000 EUR, 2005-2009 |
M. Witt |
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VOLVOX “Co-ordinated internet-linked networks for promoting innovation, exchanging knowledge and encouraging good practice to enhance bioscience education in European schools” (Sub-contract No1 to EC Contract 511180; SAS6); 38,534 EUR, matching funds 77,520 PLN; 2005-2008
PLASTOMIC "Mechanisms of transgene integration and expression in crop plant plastids: underpinning a technology for improving human health" (LSHG-CT-2003-503238); 164,160 EUR; matching funds 477 000 PLN; 2004-2007 |
J. Lilpop - SFN
J.M. Bujnicki
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APOPIS "Abnormal proteins in the pathogenesis of neurodegenerative disorders" (LSHM-CT-2003-503330); 161,200 EUR; matching funds 457 000 PLN; 2004-2006 |
J. Kuznicki
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“Continuing Education for European Biology Teachers” (QLG7-CT-2002-00573), Subcontract; 23,430 EUR, 2004 |
J. Bryk (SFN) |
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"Centre of Excellence in Molecular Bio-Medicine” (QLK6-CT-2002-90363); 350,000 EUR and supplementary grant from KBN 996,000 PLN, matching funds 30 000 PLN, 2003-2006 |
J. Kuznicki |
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"Exploiting the HSP70 chaperone machine for novel therapeutic strategies in human diseases and for the engineering of productive cellular biomolecular factories" (QLK3-CT-2000-00720); 64,776 Euro, 2003-2004
"Novel non-antibiotic treatment of staphyloccocal diseases" (QLK2-CT-2002-01250); 238,382 Euro and supplementary grant from KBN 776,000 PLN, 2002-2006 |
M. Zylicz
M. Bochtler
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"European Network for Cystic Fibrosis" (QLK3-CT-1999-00241); 9,600 Euro, 2002-2003 |
M. Witt |
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"A new Technology for Fluorescent 'Cell Chip' Immunotoxicity Testing" (QLK4/CT/2000/00787); co-ordinated; 231,703 Euro and supplementary grant from KBN 790,000 PLN, 2001-2003
"Rational engineering of lipid metabolism in flax" (QLK3/CT/2000/00349); 149,000 Euro and supplementary grant from KBN 509,500 PLN, 2001-2003 |
J. Dastych
L. Rychlewski |
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Polish Norwegian Research Fund "Aberrant synaptic plasticity in epilepsy" (PNRF-96-AI-1/07); 362,200 EUR; 2008-2010 (Project coordinator: L. Kaczmarek)
EMBO Installation Grant “Structural and biochemical studies of UvrA DNA repair protein” (1476); 250,000 EUR; 2007-2012
Wellcome Trust International Senior Research Fellowship “Structural and functional studies of two members of integrase superfamily – type 2 RNase H and Ruvc resolvase – from substrate recognition to catalysis” (081760); 4,106,806 PLN, 2007-2012
International Research Scholars: “Signaling from endosomes to the nucleus: The role of APPL proteins and their interacting partners”; Howard Hughes Medical Institute; 500,000 USD; 2006-2010
The MPI-CBG/IIMCB Partner Group at the IIMCB; 60,000 Euro; 2006-2008
“Communication between intracellular organelles in trafficking and signalling: The role of APPL proteins”, International Senior Research Fellowship of the Wellcome Trust (UK); 4,315,706 PLN; 2006-2010
Grant NIH “Kinetoplastid SL RNA biogenesis”; 100,000 USD; 2004-2009
Utrecht University fellowships for five PhD students (M. Witt’s lab, IIMCB and Institute of Human Genetics PAN, Poznan; M. Zylicz’s lab, IIMCB; A. Lipkowski’s lab, Center for Experimental and Clinical Medicine, PAN, Warsaw; L. Kaczmarek’s lab, Nencki Institute PAN, Warsaw; R. Przewlocki’s lab, Institute of Pharmacology PAN, Cracow); 10,000 EUR annually from 2004 to 2007 |
J. Jaworski
M. Nowotny
M. Nowotny
M. Miaczynska
M. Miaczynska
M. Miaczynska
J.M. Bujnicki
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EMBO & HHMI Young Investigator Programme Award; 26,000 USD and 50,000 PLN annually from 2004 to 2006 |
M. Bochtler |
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Polish National Commission for UNESCO program “Science of modern biology – exploratory resources for biology teachers and students”; 20,000 USD; 2004-2005 |
J. Lilpop |
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11 |
NIH grant CA097899-01 Innovations in Biomedical Information Science and Technology: "Discovering new human DNA repair genes by bioinformatics"; 89,000 USD subcontract (5.2003-4.2005) within a collaborative grant coordinated by Dr. A.S. Bhagwat (Wayne State University, Detroit, MI) |
J.M. Bujnicki |
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12 |
HHMI Mini-Grant to Foster Collaboration 15,000 USD (7.2003-6.2004) to Dr. J.M. Bujnicki (IIMCB) and Dr. S. Klimasauskas (Institute of Biotechnology, Vilnius, Lithuania), coordinated by Dr. S. Klimasauskas |
J.M. Bujnicki |
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HHMI Mini-Grant to Foster Collaboration 15,000 USD (7.2003-6.2004) to Dr. J.M. Bujnicki (IIMCB) and Prof. J. Otlewski (Institute of Biochemistry, University of Wroclaw, coordinated by Prof. J. Otlewski |
J.M. Bujnicki |
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"EMBO/HHMI Young Investigator Programme; 26,000 USD annually from 2003 to 2005 |
J.M. Bujnicki |
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"The Max-Planck Society (MPG) - the Polish Academy of Sciences (PAN) Junior Research Group Programme MPI-CBG in Dresden; 240,000 DM anually from 2001 to 2006" |
M. Bochtler |
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"Support for the UNESCO Professorship Chair at the IIMCB; 30,000 USD" |
M. Zylicz |
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"Utrecht University fellowships for three PhD students; 55,000 Hfl annually from 2000 to 2003; (in M. Zylicz and J. Dastych labs at the IIMCB, and one in Krakow in R. Przewlocki's lab) |
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"Investigation of mechanisms regulating expression of calmyrin 2, a novel EF-hand Ca2+-binding protein and elucidation of calmyrin 2 role in Ca2+ signal transduction in physiology and death of neurons." (N301 109 32/3854); 303,000 PLN; 2007-2010
“Role of dendrtic mRNA transport and local protein syntheis in development of dendritic arbor of neurons” (NN301314733); 300,000 PLN; 2007-2010
Proteins S-nitrosylation and Cdk5 kinase-dependent phosphorylation. Proteomic studies of synaptosomal fractions from transgenic mice - Alzheimer's disease models. (NN301254333); 70,000 PLN; 2007-2010
"Investigation of activation processes of GPCRs by theoretical methods." (NN301203833); 205,000 PLN; 2007-2010
"Modultion of activity of transription factors involved in tumorigenesis, by MDM2 and other E3 ubiquitin ligases” (NN301032534); 750,000 PLN; 2008-2011
Polish-German Special Grant “Relationship between dysregulated calcium homeostasis and synaptic pathology in Alzheimer’s disease as a target for therapy” (P-N/001/2006); 1,050,000 PLN; 2007-2010
Polish-Spanish Special Grant “Computer prediction and simulation of RNA tertiary structure formation“ (HISZPANIA/152/2006); 553,600 PLN; 2007-2010
Polish-German Special Grant "The role of cell cortex contractility in the establishment and positioning of the cleavage furrow" (JRGP/37/2005) The Max Planck Society (MPG) – the Polish Academy of Sciences (PAN) MPI-CBG Junior Research Program - Laboratory of Cortex Movement and Cell Division MGP/PAN; 3,024,200 PLN; 2006-2008
"Role of mTOR-regulated proteins in development of dendritic tree of hippocampal and cortical neurons” (2P04A01530); 220,800 PLN; 2006-2009
“Biochemical and microscopical characterization of APPLpositive endosomes“ (0394/P04/2005/28); 390,040 PLN; 2005-2008
“Identification of natural substrates for enzymes from the HINT family of phosphoroamidases and identification of enzymes that synthesize these substrates“ (0453/P04/2005/29); 352,000 PLN; 2005-2008
“Investigation of structure of presenilin protein and significance of its mutations in Alzheimer’s disease development“ (0695/P05/2005/29); 220,000 PLN; 2005-2007
“STRUF- the novel software for classification and prediction of proteins functions“ (1581/T11/2005/29); 105,000 PLN; 2005-2007
“Differences in action of stress-induced and constitutively synthesized Hsp70” (KBN-0408/P04/2004/27); 550,200 PLN; 2004-2008
“Combating bacterial resistance against MLSb antibiotics by design of a novel type of inhibitors against Erm methyltransferases” (KBN-0611/P05/2004/27); 93,000 PLN; 2004-2006
KBN-Polonium “Etude comparitive d’ARN-methyltransferases de differents organismes: un modele pour l’evolution des systemes enzimatiques de modification des acides nucleiques”; 2004-2005
Polish-German project (KBN-DAAD) “Protein-nucleic acid and protein-protein interactions in biomedically important enzymes involved in nucleic acid metabolism (DNA repair and degradation)”; 2004-2005
Polish-Czech project “Protein engineering of dehalogenating biocatalysts”; 2004-2005
"Receptors and drugs. Modeling of G Protein-Coupled Receptor and their interactions with drugs in case of opioid receptors"; (KBN-3/P05F/026/25); 120,000 PLN; 2003-2006 |
U. Wojda
J. Jaworski
A. Szybinska (subcontractor)
Coordinator: M. Dadlez, IBB
S. Filipek
M. Zylicz
J. Kuznicki
J.M. Bujnicki
E. Paluch
J. Jaworski
M. Miaczynska
P. Bieganowski
K. Jozwiak
J. Sasin
M. Zylicz
M. Feder
J.M. Bujnicki
J.M. Bujnicki
J.M. Bujnicki
S. Filipek
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"Identification of specificity deteminants of restriction endonucleases by bioinformatics and mutagenesis"; (KBN-0344/P04/2003/24); 300,000 PLN; 2003-2005 |
J.M. Bujnicki |
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"Application of bioinformatic tools to characterization of enzymes involved in DNA repair" (KBN-0503/P05/2003/24); 30,000 PLN; 2003-2004 |
M. Kurowski |
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"Hsp90 in Cancerogenesis"; (KBN-0203/P04/2002/22); 462 000 PLN; 2002-2005 |
A. Wawrzynow |
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"Calcium binding proteins interaction with presenilin 1 (PS1) in lymphocytes of Alzheimer's disease patients and healthy controls"; (KBN-0436/P04/2001/20); 325,000 PLN; 2001-2004 |
J. Kuznicki |
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"Role of glycogen synthase kinase 3 beta in neuronal death"; (KBN-0253/P04/2001/21); 270,000 PLN; 2001-2003 |
M. Hetman |
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"Molecular and Genetic Mechanisms of Neurodegeneration and Neuroprotection"; (KBN-002/CD/P05/2000); 300,000 PLN; 2001-2002, within an ordered grant co-ordinated by B. Kaminska-Kaczmarek at the Nencki Institute |
J. Kuznicki |
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"Molecular and Genetic Mechanisms of Neurodegeneration and Neuroprotection"; (KBN-002/CD/P05/2000); 260,000 PLN; 2001-2002, within an ordered grant co-ordinated by B. Kaminska-Kaczmarek at the Nencki Institute |
M. Hetman |
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"The Role of TNF-Alpha Propeptide in the Process of Storage of this Cytokine in Mast Cell Cytoplasmatic Granules"; (KBN 0254/P04/2001/21); 20,000 PLN; 2001-2002, (M. Olszewski) |
M. Olszewski |
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"Cloning and Characterisation of a Novel Human Protein Kinase"; (KBN-1114/P04/2000/19); 386,500 PLN; 2000-2003 |
L. Trzeciak |
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"Characterisation of Promoter Sequences, Transcription Factors and Signal Transduction Pathways involved in the Activation of IL-4 Gene Expression by Heavy Metal Ions"; (KBN-0564/P05/2000/18); 180,000 PLN; 2000-2002 |
J. Dastych |
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"Interaction of Chaperones with p53 Protein"; (KBN-1094/P04/2000/19); 447,000 PLN; 2000-2002 |
M. Zylicz |
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"Influence of 3'UTR sequences of IL-4 gene on stability of mRNA"; Research Grant for young investigator (KBN-1091/P04/2000/19); 18,200 PLN; 2000-2001
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D. Trzaska |
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"Ageing of the Polish population - medical, psychological, sociological and economic aspects" (PBZ-MEiN-9/2/2006); 12,178,420 PLN; 2007-2010
“Novel computer programs for homology modelling and fold recognition of RNA” (PBZ/MNiSW/07/2006/04 POLPOSTDOC III); 240,000 PLN; 2007-2010
Three tasks within an ordered grant (PBZ-MNiI-2/1/2005) “Application of contemporary functional genomics and bioinformatics to characterize and develop models of biological processes of medical and agricultural interest”: 1) Modeling of protein structures and their complexes, 2) A database of systems for DNA repair and degradation, 3) Experimental analyses of DNA repair proteins; 340,000PLN; 2006-2009
" From patterns of gene expression and regulatory motifs towards prediction and modeling of global gene expression in brain physiology and pathology" Director: B. Kaminska-Kaczmarek from Nencki Institute; within the ordered grant: "Application of functional genomics and bioinformatics for characterization and modeling of biological processes of critical importance for medicine and agriculture"; 375,000 PLN; 2006-2009
"Mechanism of biosynthesis of unusual protein-glycosaminoglycan linkage that plays key role in inflammatory processes" POL-POSTDOC II grant; 106,560 PLN
"Structural studies of restriction endonucleases generating unusual cleavage patterns" POL-POSTDOC II grant; 106,000 PLN
“Advanced molecular methods in haematology. Development and implementation of standardized research procedures for minimal residual disease, posttransplantation chimerism and marker translocations” (K126/P05/2005); 3,027,500 PLN; 2005-2009; 13 groups in Poland
"Search for diagnostic methods of Alzheimer’s disease and identification of pathogenic mechanisms as potential targets of therapies based on proteomic research in human lymphocytes” (K129/P05/2005/UMED6); 400,000 PLN; 2005-2008; (within ordered grant directed by Medical University of Lodz)
"Role of Hsp90 in regulation of gene expression involved in tumorgenic transformation", (PBZ–KBN–107/P04/2004); 1,048,000 PLN; 2004-2007, (within ordered grant directed by Jagiellonian University)
Bilateral Polish-German Ordered Research Grant (KBNK064/P05/2003) ”The transduction of neuronal Ca2+-signals via EF-hand calcium-binding proteins caldendrin and calmyrin in Alzheimer’s disease and psychotic disorders”; 955,400 PLN; 2003-2008; Director: U. Wojda with cooperation with Dr. M.R. Kreutz, Department of neurochemistry, Molecular Biology, Leibniz Institute for Neurobiology, Magdeburg
"New bioinformatic tools for proteomics and structural genomics"; (PBZ–KBN–088/PO4/2003); 1,850,000 PLN; 2004-2007, 5 groups in Poland, including 2 in IIMCB (Bujnicki and Bochtler) |
Director: P. Bledowski, coordinator M. Mossakowska
M. Boniecki
J.M. Bujnicki
Subcontractor: J. Jaworski
A. Kaczmarczyk
H. Czapinska
Director: M. Witt
Director: U. Wojda
Director: M. Zylicz
Director: U. Wojda
Director: J.M. Bujnicki
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"Genetic and Environmental Longevity Factors in a Group of Polish Centenarians"; (KBN-022/P05/1999); 1,500,000 PLN; 2001-2005, 22 groups in Poland |
Director: J. Kuznicki |
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"Addiction: Neurobiological Basis, Mechanisms, Methods of Prophylaxis and Treatment"; (KBN-033/P05/2000); 3,400,000 PLN; 2001-2005 |
Director:R. Przewlocki |
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"New tools for analysis and manipulations of nucleic acids: restriction enzymes acting on RNA and DNA-RNA hybrids" (R1200202); 1,000,000 PLN; 2007-2010 |
JM. Bujnicki |
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“Variation of restriction enzymes sequence specificities by combination of different methods of bioinformatics and protein engineering” (N30110031/3043); 278,000 PLN;
2006-2009 |
K. Skowronek |
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"Structural, evolutionary and functional classification of methyltransferase" (N30110532/3599); 49,000 PLN; 2007-2009
“Modification of the substrate specificity of Bsp6I restriction endonuclease with novel methods of directed evolution” (N30204532/3598); 50,020 PLN; 2007-2009
“A novel method for assessment of global credibility and local correctness of protein structure models” (N30110632/3600); 36,600; 2007-2009
“Studies of agonist and antagonist binding modes in opioid receptors” (N/N401/1401/33); 50,000 PLN; 2007-2009
“Sequence-structure-function relationships in apoptotic nuclease DNase II” (N40110731/2409); 30,080 PLN; 2006-2007
"Variation of restriction enzymes sequence specificities by combination
of different methods of bioinformatics and protein engineering" (3043/P01/2006/31); 278,000 PLN
"Modelling of the structure and the process of formation of the complex of oligomeric rhodopsin and trimeric G protein" (3154/P01/2006/31); 33,200 PLN; 2006-2007
"Sequence-structure-function relationships in apoptotic nuclease DNase II" (2409/P01/2006/31); 30,080 PLN
“Investigation of the structure of arrestin-rhodopsin complex by theoretical methods” (0121/P01/2006/30); 33,000 PLN; 2006-2007 |
J. M Bujnicki / K. Tkaczuk
J.M. Bujnicki / S. Pawlak
J.M. Bujnicki / M. Pawlowski
S. Filipek / M. Kolinski
J.M. Bujnicki / I. Cymerman
Skowronek
S. Filipek / K. Krzysko
M.J. Bujnicki
S. Filipek / A. Modzelewska
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"Research Grant from the State Committee for Scientific Research (KBN-6/P04B/00519) "Engineering of DNA Methytransferases"; 400,000 PLN; 2000-2003; co-ordinated at the Biology Department of the University of Warsaw |
co-ordinator: M. Radlinska, co-operator: J.M. Bujnicki |
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"Research Grant from the State Committee for Scientific Research (KBN 6P06K 04321) "Novel Vaccines against Campylobacter Jejuni"; 250,000 PLN; 2001-2004, co-ordinated at the Biology Department of the University of Warsaw |
co-ordinator: E. K. Jagusztyn-Krynicka, co-operator: J.M. Bujnicki
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Scientific Network organized by Institute of Pharmacology Polish Academy of Science – “Looking for systemic targets of potential neurotrophic drugs” (26/E-40/SN-023/2007);
78,636 PLN
Scientific Network “Mechanisms of cellular movements – Mobilitas.pl” coordinated by the Nencki Institute of Experimental Biology Polish Academy of Science (2/E-36/SN-0075/2007); 75,000 PLN
Professorial Grant from Foundation for Polish Science (SP 10/04) „Beta-catenin metabolism in health and disease”; 240,000 PLN; 2004-2008
"Research Grant from Foundation for Polish Science (FNP-15/2000) "Molecular Chaperones in Cancer Cells"; 225,000 PLN for 3 years (2000-2002) |
M. Wisniewska
M. Miaczynska
J. Kuznicki
M. Zylicz
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