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About IIMCB  History |
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Major lectures, meetings, visitors
Scientific meetings
• Symposium “Advanced Methods in Molecular Hematology”, 10.01.2007, Warsaw, Poland,
IIMCB
• “Scientific Communication” – practical course for graduate students for whom English is
a second language given by Prof. Edward Potworowski (Armand-Frappier Institute, Montreal,
Canada), 7-14.05.2007, Warsaw, Poland, IIMCB
• IIMCB Annual Report Session, 25.05.2007, Lacha, Poland
• International Annual Symposium, 01.06.2007, Warsaw, Poland, IIMCB
• 5th International Conference: Inhibitors of Protein Kinases and Workshop Session: Novel
Molecular Design and Simulation Methods, 23-27.06.2007, Warsaw, Poland, coorganized by
IIMCB
• 2nd Polish Congress of Genetics, 18-20.09.2007, Warsaw, the Warsaw University of Life
Sciences (SGGW), Poland, coorganized by IIMCB
• “New Targets and Approaches Toward Neurodegeneration and Neuroprotection”, 29.10.2007,
Warsaw, Poland coorganized by IIMCB
Seminars of invited speakers
Urszula Hibner (IGMM CNRS UMR5535, Montpellier, France) “Modulation of signal transduction pathways in hepatocarcinogenesis”, 13.02.2007
Guy Haegeman (Laboratory for Eukaryotic Gene Expression and Signal Transduction – LEGEST, Department of Molecular Biology, Ghent University, Belgium) “Molecular mechanisms
and signal transduction of inflammatory gene expression”, 22.03.2007
Grzegorz Kudla (FAS Center for Systems Biology, Harvard University, USA) “Coding sequence determinants of gene expression”, 24.04.2007
Alexander Wlodawer (Laboratory of the Macromolecular Crystallography, National Cancer Institute, Frederick, USA) “Structural basis for inhibition of translation by the tumor
suppressor Pdcd4”, 14.05.2007
Rafal Butowt (Department of Physiology, School of Medicine, University of Nevada, Reno, NV, USA) “Long-distance trafficking of trophic factors in the nervous system: The concept of trophic currencies”, 01.06.2007
Arkadiusz Chworos (Department of Physics, University of California, Santa Barbara, CA, USA) “From tecto-RNA nanoarchitectures to AFM and biosensors”, 01.06.2007
Wojciech Niedzwiedz (Department of Medicine, Cambridge University/MRC-LMB, Cambridge, UK) “Fanconi anemia: Moving forward in (cross)-linking DNA repair”, 01.06.2007
Arkadiusz Welman (Cancer Research UK, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK) “Can a biologist fix a radio? – or my approach to
functional oncogenomics”, 01.06.2007
Cezary Wojcik (Indiana University School of Medicine, Evansville, IN, USA) “VCP (valosin-containing protein; p97) in ER-associated degradation and beyond”, 01.06.2007
Susanne Wolf (Department of Neurosurgery, Stanford University, Stanford, CA, USA) “Regulation of neurogenesis in health and disease”, 01.06.2007
Robert D. Wells (Institute of Biosciences and Technology, Texas A&M University System Health Science Center, Texas Medical Center Houston, USA) “The alternate forms of DNA
microsatelites in health and disease”, 14.06.2007
Michal Hetman (Kentucky Spinal Cord Injury Research Center & Department of Neurological Surgery, University of Louisville, Louisville, USA) “Neuronal response to
transcriptional inhibition”, 20.06.2007
Paulina Dominiak (Faculty of Chemistry, Warsaw University, Poland) “Electrostatics of biological molecules based on crystallographic data”, 08.11.2007
John Moses (University of Nottingham School of Chemistry, UK) “Targeting telomerase: a click chemistry approach towards novel G-Quadruplex inhibitors”, 16.11.2007
Maurizio Memo (Faculty of Medicine, University of Brescia, Italy) “p53 involvement in Alzheimer’s disease: how fibroblasts may link neurons with lymphocytes”, 22.11.2007
Lada Biedermannova (Faculty of Science Charles University in Prague, Czech Republic) “The role of noncovalent interactions of aromatic moiety in proteins”, 12.12.2007
Scientific meetings
• “Scientific Communication” - practical course for graduate students for whom English is a second language given by Prof. Edward Potworowski (Armand-Frappier Institute, Montreal, Canada), 8-12.05.2006, Warsaw, Poland, organized by IIMCB
• International Annual Symposium 26.05.2006, Warsaw, Poland, IIMCB within the „Centre of Excellence in Molecular Bio-Medicine” project
• IIMCB Annual Report Session, 2.06.2006, Lansk, Poland
• The MPI-CBG and IIMCB Trilateral Workshop for Young Scientists from Germany, Czech Republic and Poland, focused on „Cell Biology of Intracellular Transport Processes”, supported by the Max Planck Society and IIMCB, co-organised by Dr. Marta Miaczynska (Laboratory of Cell Biology, IIMCB) and Dr. David Stanek (Charles University, Prague), 15-18.11.2006, Warsaw, Poland
Lectures within Centre of Excellence in Molecular Bio-Medicine project
Gennady Ermak (Ethel Percy Andrus Gerontology Center and Division of Molecular and Computational Biology, University of Southern California, Los Angeles, USA) RCAN1 Functions in Neuronal Development and Degeneration. 26.05.2006
Shermali Gunawardena (Department of Cellular and Molecular Medicine, University of California, San Diego, USA) Deadly pile-ups on neuronal highways: Transport problems in
neurodegenerative disease. 26.05.2006
Sebastien Holbert (INRA, Tours, France) Large screen of neurodevelopmental diseases candidate genes. 26.05.2006
Anna Moszczynska Mirecki (Molecular Neurobiology Laboratory, Department of Neuroscience Research, Centre for Addiction and Mental Health, Toronto, Canada) Parkin-dopamine transporter protein-protein interaction: Implications for Parkinson’s disease. 26.05.2006
Marcin Nowotny (Wei Yang Laboratory, National Institutes of Health, NIDDK/LMB, Bethesda, MA, USA) Structural studies of RNase H from substrate binding to two-metal catalysis. 26.05.2006
Matthias Soller (Department of Biology, Brandeis University, Waltham, USA) ELAV regulated pre-mRNA processing in synaptic growth. 26.05.2006
Manuela Bartolini (University of Bologna, Italy) Combined in vitro methodologies for drug discovery in Alzheimer’s disease. 16.03.2006
Pawel Smialowski (Technische Universität München, Germany) Attempts to predict structure determination success from sequence. 3.03.2006
Nils Holger Axelsen (Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark) Scientific dishonesty and good scientific practice. 4.04.2006
Seth Jon Davis (Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, Cologne, Germany) Molecular-genetic perception of dawn and dusk:
input regulation of the circadian clock. 7.04.2006
Fred Van Leuven (Experimental Genetics Group – LEGT EGG, Dept. of Human Genetics, Katholieke Universiteit Leuven, Belgium) Different transgenic mouse models for different
aspects of Alzheimer’s disease. 23.05.2006
Casper Hoogenraad (Department of Neuroscience, Erasmus Medical Center, Rotterdam, the Netherlands) Receptor trafficking regulates dendrite morphology. 2.10.2006
Volker Gerke (Institute of Medical Biochemistry ZMBECenter for Molecular Biology of Inflammation, Muenster, Germany) Mechanisms controlling distinct steps in leukocyte
transendothelial migration. 10.11.2006
Jochen Herms (Zentrum fur Neuropathologie und Prionforschung Ludwig Maximilians Universitat, Munich, Germany) Application of the in vivo two-photon microscopy in
neurodegenerative diseases. 9.11.2006
Daumantas Matulis (Laboratory of Biothermodynamics and Drug Design, Institute of Biotechnology, Vilnius, Lithuania) Radicicol binding to Hsp90 by thermal shift assay. 15.12.2006
Seminars of invited speakers
Dorota Religa (Karolinska Institute, Stockholm & Medical Research Center, Warsaw) Polish Brain Power - development of Biobank. 5.01. 2006
Lukasz Jaroszynski (Institute of Human Genetics, Georg-August-University, Göttingen, Germany) Expression and functional analysis of Tex18 and Stra8 genes in male germ cells.
12.01.2006
Malgorzata Borowiak (Max Delbruck Center for Molecular Medicine, Berlin, Germany) Met as a part of general, defensive response to tissue injury. 9.02.2005
Hansjürgen Volkmer (NMI Natural and Medical Sciences Institute at the University of Tübingen, Germany) Function and regulation of cell adhesion molecules for the establishment of
neuronal connectivity. 10.02.2006
Jakub Golab (Department of Immunology, Center of Biostructure Research, Medical University of Warsaw, Poland) Potential antitumor effects of statins. 16.02.2006
Kristian Rother (Institut für Biochemie CCM, Charite - Universitätsmedizin Berlin, Germany) Columba - integrating annotation on protein structures. 12.04.2006
Magda Kosmopoulou (The National Hellenic Research Foundation, Athens, Greece) Glycogen phosphorylase as molecular target for the development of new potent drugs for type 2
diabetes therapy. 25.04.2006
Lyudmila L. Sidorik (Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kiev, Ukraine) The role of molecular chaperons in dilated cardiomyopathy
progression. 27.04.2006
Björn Wallner (Stockholm University, AlbaNova University Center, Stockholm Bioinformatics Center, Sweden) Prediction of protein model quality. 8.05.2006
Jaroslaw Marszalek (Intercollegiate Faculty of Biotechnology UG-AMG Department of Molecular and Cellular Biology, Gdansk) The evolution of mitochondrial chaperones utilized in Fe-S cluster biogenesis. 23.06.2006
Anthone W. Dunah (Mass General Institute for Neurodegenerative Disease, Harvard Medical School and Massachusetts General Hospital, Charlestown, USA) Functions and mechanisms
of LAR receptor protein tyrosine phosphatases in the development and maintenance of excitatory synapses in brain. 13.07.2006
John Moses (The London School of Pharmacy University of London, Great Britain) Biomimetic synthesis of complex natural products. 28.07.2006
Richard J. Roberts (New England Biolabs, Inc, Ipswich, USA) The genomics of restriction and modification. 15.09.2006
Marek Cieplak (Institute of Physics PAN, Warsaw, Poland) Stretching to understand proteins. 28.11.2006
Ashok S. Bhagwat (Department of Chemistry, Wayne State University, Detroit, USA) Antibody maturation caused by human AID: roles of transcription and DNA repair. 16.05.2006
Scientific meetings
• 4th International Conference „Inhibitors of Protein Kinases”, 25-29.06.2005, Warsaw, Poland, organizer: Interdisciplinary Center for Mathematical and Computational Modeling; coorganizers: Institute of Biochemistry and Biophysics PAN, Institute of Biocybernetics and Biomedical Engineering, Division of Biophysics – Institute of Experimental Physics, University of Warsaw and IIMCB
• EMBO Workshop „Frontiers of Molecular Biology”, 14-18.10.2005, Jachranka, Poland, organized by EMBO and IIMCB
• SMM 5th Integrated Course – „Advances in molecular medicine: focus on molecular endocrinology” consisted of a conference „Molecular endocrinology – from gene to disease” and a practical course „Molecular endocrinology in clinical practice”, 26.06-1.07.2005, Gliwice, coorganized by IIMCB within the „Centre of Excellence in Molecular Bio-Medicine” project
• SMM Lecture Course on Human Genetics, 1-2.06.2005, Warsaw, organized by SMM and IIMCB
• International Annual Symposium, 10-11.06.2005, Warsaw, Poland, IIMCB within the „Centre of Excellence in Molecular Bio-Medicine” project
• IIMCB Annual Report Session, 6.05.2005, Mierki, Poland
• 28.05-2.06.2005 EMBO-FEBS Workshop on Biology of Molecular Chaperones: Heat Shock Proteins in Molecular Medicine, Misfolding Diseases and Cancer, Zakopane, Poland; sponsored
by European Molecular Biology Organisation (EMBO), The Federation of European Biochemical Societies (FEBS) and the Centre of Excellence in Molecular Bio-Medicine of the International Institute of Molecular and Cell Biology in Warsaw; organized and chaired by Professor Maciej Zylicz from IIMCB and Prof. Ulrich Hartl from MPG, Germany
• SMM Annual Scientific Report Session, 10-11.10.2005, Warsaw, organized by SMM, Medical University of Warsaw and IIMCB
Lectures within Centre of Excellence in Molecular Bio-Medicine project
Guido Tarone (Department of Genetics, Biology and Biochemistry, University of Torino) Integrin signaling and mechanotransduction in the heart. 14.02.2005
Kathryn Ball (CRUK Interferon and Cell Signalling Group, Cancer Research Centre, University of Edinburgh) Defining steps on the pathway leading to activation of the IRF-1tumour suppressor. 9.03.2005
Heymut Omran (Universitaets-Kinderklinik, Freiburg) DNAH5 and DNAI1 mutations cause mis-localization of the outer dynein arm heavy chains DNAH5 and DNAH9. 17.03.2005
Henri Grosjean (Director of Research CNRS, Laboratory of Structural Enzymology and Biochemistry (LEBS) Gif-sur-Yvette) Comparative analysis of tRNA sequences in genomes of
the 3 biological domains. 26.04.2005
Bruno Lapeyre (Centre de Recherche de Biochimie, Macromoleculaire du CNRS, Montpellier) RNA MTases in yeast: bending the rules. 3.06.2005
Pawel Bieganowski (IIMCB) Hints from the histidine triad family. 10.06.2005
Jacek Jaworski (Howard Hughes Medical Institute & Picower Center for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA) Regulation of dendritic arbor development by the PI3K- Akt-mTOR signaling pathway. 10.06.2005
Agnieszka Kobielak (Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY) Alpha-catenin: at the junction of intercellular adhesion and actin dynamics. 10.06.2005
Krzysztof Kobielak (Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY) Regulation of hair follicle morphogenesis by BMP signaling. 10.06.2005
Ewa Paluch (UMR168 Physico-Chimie Curie, Institut Curie/CNRS, Paris) How actomyosin contractility and cortical flows govern cell shape dynamics. 27.06.2005 (lecture given at the
Nencki Institute of Experimental Biology PAN, Warsaw)
Berta Alsina (Development Biology Group, Department of Health and Experimental Sciences, Universitat Pompeu Fabra) Neurogenesis and compartment formation in the inner ear development. 11.07.2005
Villa-Freixa Jordi (Computational Biochemistry and Biophisics, Universitat Pompeu Fabra) From micro – to macroscopic approaches to the dynamics of biochemical processes. 11.07.2005
David T. F. Dryden (University of Edinburgh) Making and breaking a biomolecular machine. 30.08.2005
Pierre Formstecher (Inserm U459, Université Lille 2, Faculté de Medecine Henri Warembourg) From stem cell to cell death. A new concept in epithelial cell biology and cancer. 26.09.2005
Iwona Pilecka (Serono Pharmaceutical Research Institute, Geneva) Downregulation of receptor tyrosine kinases by Cbl and CIN85. 13.10.2005
Eric Westhof (Université Louis Pasteur, Strasbourg) RNA selfassembly motifs. 3.11.2005
• 4th Integrated Course – Advances in Molecular Medicine: Molecular therapy in clinical practice, 29.03.-02.04.2004, Poznan, organized by: Postgraduate School of Molecular
Medicine (SMM), Department of Cancer Immunology, Oncology Chair, University of Medical Sciences in Poznan, Wielkopolska Cancer Center in Poznan and IIMCB within the Centre of Excellence in Molecular Bio-Medicine project
• Seminar Management tools for excellent science 30.03.2004, organized by Polish Academy of Sciences, Max Planck Society and IIMCB
• Seminar A novel platform for cell-specific molecular analysis, 21.04.2004 co-organized by IIMCB, TK Biotech (Poland) and Arcturus (USA)
• Seminar of participants of KBN ordered research grant: Genetic and Environmental Longevity Factors in a Group of Polish Centenarians, 7-8.05.2004 (approx. 50 participants from 20 Polish institutes) organized by IIMCB
• Internal review session of the Institute, Mierki, Poland, 28.05.2004, organized by IIMCB
• SMM Spring School Lecture Course on Human Genetics, 3-4.06.2004, Warsaw, co-organized by IIMCB and SMM
• International Annual Symposium, 25.06.2004, Warsaw, Poland, IIMCB within the Centre of Excellence in Molecular Bio-Medicine project
• Workshop Molecular basis of Alzheimer’s disease, 2-3.07.2004, Warsaw, Poland, organized by IIMCB within the Centre of Excellence in Molecular Bio-Medicine project and Medical Research Center PAN
• Workshop Bridges in Life Sciences, 06.10.2004, Warsaw, Poland; organized by IIMCB in cooperation with National Institutes of Health and Cedar Sinai Medical Center, USA
• Annual Scientific Report Session, 18-19.10.2004, Warsaw, organized by SMM, Medical University of Warsaw and IIMCB
• 6th Winter School From gene to protein, from structure to function and dysfunction, 29.11-3.12.2004, Warsaw, organized by SMM and IIMCB
Lectures by invited guests
Edward Brown (Department of Radiation Oncology, Massachusetts General Hospital, USA) Can antitumor therapy be improved with multiphoton laser scanning microscopy? 25.06.2004
Anna Majewska (Center for Learning and Memory, Massachusetts Institute of Technology, USA) Imaging of synaptic structure in the visual cortex in vivo, 25.06.2004
Piotr Stepien (Department of Genetics, University of Warsaw, Poland) Human mitochondria: much more than just energy production, 25.06.2004
Maria Barcikowska (Medical Research Center, Warsaw, Poland) Frontotemporal dementia: disease or syndrome? 02.07.2004
Pawel P. Liberski (Medical University of Lodz, Poland) Molecular diagnosis of a prion disease, 03.07.2004
Pawel Lukow (Institute of Philosophy Warsaw University, Poland) Informed consent and genetic information, 03.07.2004
A. Kowalska (Institute of Human Genetics, Poznan, Poland) AD related mutations in Polish population, 03.07.2004
Peter Hedera (Vanderbilt University, USA) Ethical principles and pitfalls of genetic testing for dementia, 03.07.2004
Zbigniew Zalewski (Jagellonian University, Krakow, Poland) Philosophical aspects of genetic testing, 03.07.2004
Magdalena Gacia (Medical Research Center, Warsaw, Poland) PSEN1 promoter polymorphisms in Polish AD cohort, 03.07.2004
Jaroslaw Marszalek (Interdisciplinary Faculty of Biotechnology UG/AMG, Poland) Specialized mitochondrial Hsp 70 system involved in Fe-S clusters biogenesis – functional interactions and evolution, 09.12.2004
Krzysztof Drabikowski (Friedrich Miescher Institute, Basel, Switzerland) Sumoylation in C. elegans, a global approach, 23.12.2004
V. Renugopalakrishnan (Harvard Medical School, Boston, USA) Bionanotechnological applications of proteins – a bottom up approach, 13.09.2004
Lectures within Centre of Excellence in Molecular Bio-Medicine project
Peter Bader (University Children’s Hospital Tübingen, Germany) Chimerism and Minimal Residual Disease in Children transplanted for ALL, 10.03.2004
Brage S. Andresen (Unit for Molecular Medicine, Inst. of Human Genetics, Aarhus University, Denmark) Missplicing at the root of phenotypic variation in human disease - Examples from the Acyl-CoA dehydrogenase genes, 17.03.2004
Boudewijn Burgering (Department of Physiological Chemistry University Medical Center Utrecht, The Netherlands) Forkhead transcription factors and the control of cellular oxidative stress, 02.04.2004
Cisca Wijmenga (University Medical Center Utrecht, Complex Genetics Group Dept.of Biomedical Genetics, The Netherlands) The hunt for celiac disease genes: a genomics approach, 26.05.2004
Saulius Klimasauskas (HHMI International Research Scholar, Institute of Biotechnology, Vilnius, Lithuania) Mechanisms of DNA cytosine methylation, 22.06.2004
Sebastiaan Werten (Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France) Structural biology of transcription cofactors, 25.06.2004
Ulrich Finckh (University Hospital Eppendorf, Institute of Human Genetics, Germany), Genetic studies on Alzheimer’s disease: current status and future prospects, 02.07.2004
Robert Layfield (University of Nottingham Medical School, Great Britain), The role of ubiquitin-mediated proteolysis in neurodegenerative disorders, 02.07.2004
Fred van Leeuwen (Netherlands Institute for Brain Research, Amsterdam, The Netherlands), Molecular misreading as a contributor to the neuropathogenesis of Alzheimer’s disease, 02.07.2004
Marc Cruts (Department of Molecular Genetics VIB8 University of Antwerp, Belgium), Mutation detection and characterization in neurodegenerative conditions, 03.07.2004
Tim Clausen (Research Institute of Molecular Pathology, Austria) Structure and function of the DegS stress sensor, 23.08.2004
Henri Grosjean (Laboratoire d’Enzymologie et Biochimie Structurales, CNRS, Gif-sur-Yvette, France) tRNA modification in the three Domains of Life, 23.08.2004
Gordana Maravic (Department of Biochemistry and Molecular Biology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Croatia) rRNA methylation and antibiotic resistance, 27.08.2004
Pier Franco Pignatti (Instituto di Biologia e Genetica, Universita di Verona, Italy) Molecular biomedicine and the unraveling of complex phenotypes: the example of cardiovascular disease genetics and pharmacogenetics, 6.09.2004
January Weiner III (Division of Bioinformatics, The Westfalian Wilhelms University of Muenster, Germany) Circular permutations and the domain-wise evolution of proteins, 10.09.2004
Jiri Damborsky (EMBO/HHMI Scientist Josef Loschmidt Professor of Chemistry National Centre for Biomolecular Research Masaryk University, Brno, Czech Republic) Computer-assisted protein engineering of enzymes, 24.09.2004
Claudio Franceschi (University of Bologna, Department of Immunology INRCA, Ancona, Italy), Genetics of longevity, 01.10.2004
Ted Hupp (University of Edinburgh, Cancer Research Centre, UK) Control of gene expression by the tumour suppressor p53, 10.11.2004
Michael R. Kreutz (Department of Neurochemistry and Molecular Biology Leibnitz Institute for Neurobiology in Magdeburg, Germany) The enigmas of synapto-dendritic Ca2+-signaling, 18.11.2004
Alfred M. Pingoud (Institute of Biochemistry, Justus-Liebig-Universitaet, Giessen, Germany) Structure, function and evolution of homing endonucleases, 26.11.2004
Gregor Meiss (Institute of Biochemistry, Justus-Liebig-Universitaet, Giessen, Germany) Regulation and enzymology of apoptotic nucleases, 26.11.2004
Krzysztof Skowronek & Sebastian Pawlak, (Laboratory of Bioinformatics and Protein Engineering, IIMCB) Prediction-validation approach for preliminary structural characterization
of restriction endonucleases: case studies, 26.11.2004
Marcin Feder (Laboratory of Bioinformatics and Protein Engineering, IIMCB) A new, unusual family of PD-(D/E)XK nucleases, 26.11.2004
Marja Jäättelä (Institute of Cancer Biology of the Danish Cancer Society, Denmark) Lysosomal control of programmed cell death, 06.12.2004
Edward F. Knol (University Medical Center, Department of Dermatology and Allergology, Utrecht, The Netherlands) Local and systemic factors in atopic dermatitis: relation atopy and other allergic diseases, 08.12.2004
Rolf Herrmann (Institut fur Medizinische Physik und Biophysik Charite – Iniversitatsmedizin, Berlin, Germany) Signal transduction from GPCRs to G proteins, 10.12.2004
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