Molecular haematology project

It is an ministerial commissioned project entitled: Advanced molecular methods in haematology. Work out and implementation of standards of minimal residual disease, posttransplant chimerism and marker translocations analysis. The project with the overall budget of about 3 mln PLN links elements of pediatric and adult molecular haematology related to basic research and practical applications. The consortium is composed of the major Polish centers of molecular haematology in Poznan, Warsaw, Cracow, Lublin and Zabrze what constitutes the core of a future reference laboratories network active in this area in Poland. Haematological disorders selected for the study by the consortium are: pediatric acute lymphoblastic leukemia (ALL), pediatric and adult acute myeloid leukemia (AML), chronic myeloid leukemia (CML) and non-Hodgkin lymphomas (NHL); they were chosen as model disorders being already analysed on a molecular level in some of the Polish centers.
A posttransplant chimerism and a minimal residual disease (MRD) are being analysed in connection to the disorders listed above. The project also aims at constructing the database linking available clinical and molecular data of patients recruited to the program and also on establishing the multicenter collection of relevant biological material. The program was initiated at IIMCB and is being conducted by Prof. Michal Witt and coordinated by Dr. Malgorzata Mossakowska.

More information (in Polish): http://www.iimcb.gov.pl/hematologia_molekularna.php