The Opera Phenix, a high-content screening system from PerkinElmer, was installed at IIMCB. Opera Phenix is a spinning disk-based confocal microscope equipped with two cameras, a laser-based autofocus system and an automated system for water immersion. The microscope can scan automatically multi-well plates and slides. Moreover, the system installed at IIMCB has a robotic arm for automated plate handling. The system was purchased with funds provided by the Ministry of Science and Higher Education.