Höhfeld J, Benzing T, Bloch W, Fürst DO, Gehlert S, Hesse M, Hoffmann B, Hoppe T, Huesgen PF, Köhn M, Kolanus W, Merkel R, Niessen CM, Pokrzywa W, Rinschen MM, Wachten D, Warscheid B.

Maintaining proteostasis under mechanical stress.

EMBO Rep.

Das A, Thapa P, Santiago U, Shanmugam N, Banasiak K, Dabrowska K, Nolte H, Szulc NA, Gathungu RM, Cysewski D, Krüger M, Dadlez M, Nowotny M, Camacho CJ, Hoppe T, Pokrzywa W.

Heterotypic Assembly Mechanism Regulates CHIP E3 Ligase Activity.

bioRxiv preprint August 20, 2021

Turek M, Banasiak K, Piechota M, Shanmugam N, Macias M, Śliwińska MA, Niklewicz M, Kowalski K, Nowak N, Chacinska A, Pokrzywa W.

Muscle-derived exophers promote reproductive fitness.

EMBO Rep.

Banasiak K, Szulc NA, Pokrzywa W.

The Dose-Dependent Pleiotropic Effects of the UBB+1 Ubiquitin Mutant.

Front. Mol. Biosci.

2020

Donkervoort S, Kutzner CE, Hu Y, Lornage X, Rendu J, Stojkovic T, Baets J, Neuhaus SB, Tanboon J, Maroofian R, Bolduc V, Mroczek M, Conijn S, Kuntz NL, Töpf A, Monges S, Lubieniecki F, McCarty RM, Chao KR, Governali S, Böhm J, Boonyapisit K, Malfatti E, Sangruchi T, Horkayne-Szakaly I, Hedberg-Oldfors C, Efthymiou S, Noguchi S, Djeddi S, Iida A, di Rosa G, Fiorillo C, Salpietro V, Darin N, Faure´ J, Houlden H, Oldfors A, Nishino I, de Ridder W, Straub V, Pokrzywa W, Laporte J, Foley R, Romero NB, Ottenheijm C, Hoppe T, Bönnemann CG.

Pathogenic Variants in the Myosin Chaperone UNC-45B Cause Progressive Myopathy with Eccentric Cores.

Am. J. Hum. Genet.

Albert M-C, Brinkmann K, Pokrzywa W, Günther SD, Krönke M, Hoppe T, Kashkar H.

CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage.

Cell Death & Disease

Turek M, Piechota M, Shanmugam N, Niklewicz M, Kowalski K, Chacińska A, Pokrzywa W.

Nutritional status and fecundity are synchronised by muscular exopheresis.

bioRxiv

Fatima A, Irmak D, Noormohammadi A, Rinschen MM, Das A, Leidecker O, Schindler C, Sánchez-Gaya V, Wagle P, Pokrzywa W, Hoppe T, Rada-Iglesias A, Vilchez D.

The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells.

Commun Biol.

Macnar JM, Szulc N, Kryś JD, Badaczewska-Dawid AE, Gront D.

Article BioShell 3.0: Library for Processing Structural Biology Data.

Biomolecules

Thapa P, Shanmugam N, Pokrzywa W.

Ubiquitin Signaling Regulates RNA Biogenesis, Processing, and Metabolism.

BioEssays

2018

Koyuncu S, Saez I, Lee HJ, Gutierrez-Garcia R, Pokrzywa W, Fatima A, Hoppe T, Vilchez D.

The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients.

Nat Commun.

Balaji V, Pokrzywa W, Hoppe T.

Ubiquitylation Pathways In Insulin Signaling and Organismal Homeostasis.

Bioessays

2017

Pokrzywa W, Hoppe T.

CHIPped balance of proteostasis and longevity.

Oncotarget

Pokrzywa W, Lorenz R, Hoppe T

Chaperone-directed ubiquitylation maintains proteostasis at the expense of longevity.

Worm (in press)

Kevei É, Pokrzywa W, Hoppe T

Repair or Destruction: An Intimate Liaison Between Ubiquitin Ligases and Molecular Chaperones in Proteostasis

FEBS Lett. doi:10.1002/1873-3468.12750.