Publications

All publications

2018

Banach-Orłowska M, Jastrzębski K, Cendrowski JMaksymowicz M, Wojciechowska K, Korostyński M, Moreau D, Gruenberg J, Miaczynska M.

The topology of lymphotoxin β receptor accumulated upon endolysosomal dysfunction dictates the NF-κB signaling outcome.

J Cell Sci.

2017

Szymanska E, Budick-Harmelin N, Miaczynska M.

Endosomal "sort" of signaling control: The role of ESCRT machinery in regulation of receptor-mediated signaling pathways.

Semin Cell Dev Biol.

Jastrzębski K, Zdżalik-Bielecka D, Mamińska A, Kalaidzidis Y, Hellberg C, Miaczynska M

Multiple routes of endocytic internalization of PDGFRβ contribute to PDGF-induced STAT3 signaling

J Cell Sci.

2016

Tudek B, Zdżalik-Bielecka D, Tudek A, Kosicki K, Fabisiewicz A, Speina E

Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes

Free Radic Biol Med

Mikula M, Skrzypczak M, Goryca K, Paczkowska K, Ledwon JK, Statkiewicz M, Kulecka M, Grzelak M, Dabrowska M, Kuklinska U, Karczmarski J, Rumienczyk I, Jastrzebski K, Miaczynska M, Ginalski K, Bomsztyk K, Ostrowski J.

Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.

Nucleic Acids Res

Cendrowski J, Mamińska A, Miaczynska M

Endocytic regulation of cytokine receptor signaling

Cytokine Growth Factor Rev

Song J, Mu Y, Li C, Bergh A, Miaczynska M, Heldin CH, Landström M

APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain

Oncotarget

Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M

ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors

Sci Signal

Szymanska E, Skowronek A, Miaczynska M

Impaired dynamin 2 function leads to increased AP-1 transcriptional activity through the JNK/c-Jun pathway

Cell Signal

2015

Kalaidzidis I, Miaczynska M, Brewińska-Olchowik M, Hupalowska A, Ferguson C, Parton RG, Kalaidzidis Y, Zerial M

APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments

J Cell Biol

Banach-Orlowska M, Szymanska E, Miaczynska M

APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription

FEBS Lett

Torun A, Szymańska E, Castanon I, Wolińska-Nizioł L, Bartosik A, Jastrzębski K, Miętkowska M, González-Gaitán M, Miaczynska M

Endocytic adaptor protein Tollip inhibits canonical Wnt signaling

PLoS One

Kolanczyk M, Krawitz P, Hecht J, Hupalowska A, Miaczynska M, Marschner K, Schlack C, Emerich D, Kobus K, Kornak U, Robinson PN, Plecko B, Grangl G, Uhrig S, Mundlos S, Horn D

Missense variant in CCDC22 causes X-linked recessive intellectual disability with features of Ritscher-Schinzel/3C syndrome

Eur J Hum Genet

2014

Sadowski Ł, Jastrzębski K, Purta E, Hellberg C, Miaczynska M

Labeling of platelet-derived growth factor by reversible biotinylation to visualize its endocytosis by microscopy

Methods Enzymol.

2013

Miaczynska M

Effects of membrane trafficking on signaling by receptor tyrosine kinases

Cold Spring Harb Perspect Biol.

Sadowski L, Jastrzębski K, Kalaidzidis Y, Heldin CH, Hellberg C, Miaczynska M

Dynamin Inhibitors Impair Endocytosis and Mitogenic Signaling of PDGF

Traffic

Pyrzynska B, Banach-Orlowska M, Teperek-Tkacz M, Miekus K, Drabik G, Majka M, Miaczynska M

Multifunctional protein APPL2 contributes to survival of human glioma cells

Mol Oncol.

2012

Winiarska M, Nowis D, Bil J, Glodkowska-Mrowka E, Muchowicz A, Wanczyk M, Bojarczuk K, Dwojak M, Firczuk M, Wilczek E, Wachowska M, Roszczenko K, Miaczynska M, Chlebowska J, Basak GW, Golab J

Prenyltransferases Regulate CD20 Protein Levels and Influence Anti-CD20 Monoclonal Antibody-mediated Activation of Complement-dependent Cytotoxicity

J Biol Chem

Zerrouqi A, Pyrzynska B, Febbraio M, Brat DJ, Van Meir EG

P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3

J Clin Invest.

Hupalowska A, Pyrzynska B, Miaczynska M

APPL1 regulates basal NF-κB activity by stabilizing NIK

J Cell Sci

Hupalowska A, Miaczynska M

The new faces of endocytosis in signaling

Traffic

2011

Urbanska A, Sadowski L, Kalaidzidis Y, Miaczynska M

Biochemical characterization of APPL endosomes: the role of annexin A2 in APPL membrane recruitment

Traffic

Pilecka I, Sadowski L, Kalaidzidis Y, Miaczynska M

Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment

Exp Cell Res

2010

Miaczynska M, Bar-Sagi D

Signaling endosomes: seeing is believing

Curr Opin Cell Biol

2009

Ohya T, Miaczynska M, Coskun U, Lommer B, Runge A, Drechsel D, Kalaidzidis Y, Zerial M

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.

Nature

Olchowik M, Miaczyńska M

[Effectors of GTPase Rab5 in endocytosis and signal transduction]

Postepy Biochem

Banach-Orlowska M, Pilecka I, Torun A, Pyrzynska B, Miaczynska M

Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex

Biochem J

Sadowski L, Pilecka I, Miaczynska M

Signaling from endosomes: location makes a difference.

Exp Cell Res

Rashid S, Pilecka I, Torun A, Olchowik M, Bielinska B, Miaczynska M

Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription.

J Biol Chem

Pyrzynska B, Pilecka I, Miaczynska M

Endocytic proteins in the regulation of nuclear signaling, transcription and tumorigenesis

Mol Oncol

2008

Kubiak JZ, Ciemerych MA, Hupalowska A, Sikora-Polaczek M, Polanski Z

On the transition from the meiotic to mitotic cell cycle during early mouse development.

Int J Dev Biol

Miaczynska M, Stenmark H

Mechanisms and functions of endocytosis.

J Cell Biol

2007

Pilecka I, Banach-Orlowska M, Miaczynska M

Nuclear functions of endocytic proteins

Eur J Cell Biol