Publications

All publications

2018

Hareza A, Bakun M, Świderska B, Dudkiewicz M, Koscielny A, Bajur A, Jaworski J, Dadlez M, Pawłowski K.

Phosphoproteomic insights into processes influenced by the kinase-like protein DIA1/C3orf58.

PeerJ.

Firkowska M, Macias M, Jaworski J.

ESCRT Proteins Control the Dendritic Morphology of Developing and Mature Hippocampal Neurons.

Mol Neurobiol.

Koscielny A, Malik AR, Liszewska E, Zmorzynska J, Tempes A, Tarkowski B, Jaworski J

Adaptor Complex 2 Controls Dendrite Morphology via mTOR-Dependent Expression of GluA2

Mol Neurobiol

2017

Urbanska M, Gozdz A, Macias M, Cymerman IA, Liszewska E, Kondratiuk I, Devijver H, Lechat B, Van Leuven F, Jaworski J.

GSK3β Controls mTOR and Prosurvival Signaling in Neurons.

Mol Neurobiol.

Gozdz A, Nikolaienko O, Urbanska M, Cymerman IA, Sitkiewicz E, Blazejczyk M, Dadlez M, Bramham CR, Jaworski J

GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation

Front Mol Neurosci

Urbanska AS, Janusz-Kaminska A, Switon K, Hawthorne AL, Perycz M, Urbanska M, Bassell GJ, Jaworski J

ZBP1 phosphorylation at serine 181 regulates its dendritic transport and the development of dendritic trees of hippocampal neurons

Sci Rep

de Hoz L, Gierej D, Lioudyno V, Jaworski J, Blazejczyk M, Cruces-Solís H, Beroun A, Lebitko T, Nikolaev T, Knapska E, Nelken I, Kaczmarek L

Blocking c-Fos Expression Reveals the Role of Auditory Cortex Plasticity in Sound Frequency Discrimination Learning

Cereb Cortex

Kononenko NL, Claßen GA, Kuijpers M, Puchkov D, Maritzen T, Tempes A, Malik AR, Skalecka A, Bera S, Jaworski J, Haucke V

Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration

Nat Commun

Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J

Molecular neurobiology of mTOR

Neuroscience

Blazejczyk M, Macias M, Korostynski M, Firkowska M, Piechota M, Skalecka A, Tempes A, Koscielny A, Urbanska M, Przewlocki R, Jaworski J

Kainic Acid Induces mTORC1-Dependent Expression of Elmo1 in Hippocampal Neurons

Mol Neurobiol

Kondratiuk I, Łęski S, Urbańska M, Biecek P, Devijver H, Lechat B, Van Leuven F, Kaczmarek L, Jaworski T

GSK-3β and MMP-9 Cooperate in the Control of Dendritic Spine Morphology

Mol Neurobiol

2016

Kędra M, Jaworski J, Zmorzyńska J.

Okiem ryby - nowe spojrzenie na rozwój sieci neuronalnych i choroby neurorozwojowe.

Wszechświat

Jasińska M, Miłek J, Cymerman IA, Łęski S, Kaczmarek L, Dziembowska M

miR-132 Regulates Dendritic Spine Structure by Direct Targeting of Matrix Metalloproteinase 9 mRNA

Mol Neurobiol.

Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J

Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches

IUBMB Life

Skałecka A, Liszewska E, Bilinski R, Gkogkas C, Khoutorsky A, Malik AR, Sonenberg N, Jaworski J

mTOR kinase is needed for the development and stabilization of dendritic arbors in newly born olfactory bulb neurons

Dev Neurobiol

van Scheppingen J, Iyer AM, Prabowo AS, Mühlebner A, Anink JJ, Scholl T, Feucht M, Jansen FE, Spliet WG, Krsek P, Zamecnik J, Buccoliero AM, Giordano F, Genitori L, Kotulska K, Jozwiak S, Jaworski J, Liszewska E, van Vliet EA, Aronica E

Expression of microRNAs miR21, miR146a, and miR155 in tuberous sclerosis complex cortical tubers and their regulation in human astrocytes and SEGA-derived cell cultures

Glia

Kevenaar JT, Bianchi S, van Spronsen M, Olieric N, Lipka J,Frias CP, Mikhaylova M, Harterink M, Keijzer N, Wulf PS, Hilbert M, Kapitein LC, de Graaff E, Ahkmanova A, Steinmetz MO, Hoogenraad CC

Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity

Curr Biol

Lipka J, Kapitein LC, Jaworski J, Hoogenraad CC

Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites

EMBO J

Wasiak I, Kulikowska A, Janczewska M, Michalak M, Cymerman IA, Nagalski A, Kallinger P, Szymanski WW, Ciach T

Dextran Nanoparticle Synthesis and Properties

PLoS One

2015

Kulcenty K, Wróblewska J, Mazurek S, Liszewska E, Jaworski J.

Molecular mechanisms of induced pluripotency.

Contemp Oncol (Pozn)

Esteves da Silva M, Adrian M, Schätzle P, Lipka J, Watanabe T, Cho S, Futai K, Wierenga CJ, Kapitein LC, Hoogenraad CC

Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture

Cell Rep

Malik AR, Liszewska E, Skalecka A, Urbanska M, Iyer AM, Swiech LJ, Perycz M, Parobczak K, Pietruszka P, Zarebska MM, Macias M, Kotulska K, Borkowska J, Grajkowska W, Tyburczy ME, Jozwiak S, Kwiatkowski DJ, Aronica E, Jaworski J

Tuberous sclerosis complex neuropathology requires glutamate-cysteine ligase

Acta Neuropathol Commun

Malik AR, Liszewska E, Jaworski J

Matricellular proteins of the Cyr61/CTGF/NOV (CCN) family and the nervous system

Front Cell Neurosci

Cymerman IA, Gozdz A, Urbanska M, Milek J, Dziembowska M, Jaworski J

Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3βMistargeted mitochondrial proteins activate a proteostatic response in the cytosol

PLoS One

2014

Geiger JC, Lipka J, Segura I, Hoyer S, Schlager MA, Wulf PS, Weinges S, Demmers J, Hoogenraad CC, Acker-Palmer A

The GRIP1/14-3-3 Pathway Coordinates Cargo Trafficking and Dendrite Development

Dev Cell

Skupien A, Konopka A, Trzaskoma P, Labus J, Gorlewicz A, Swiech L, Babraj M, Dolezyczek H, Figiel I, Ponimaskin E, Wlodarczyk J, Jaworski J, Wilczynski GM, Dzwonek J

CD44 regulates dendrite morphogenesis through Src tyrosine kinase-dependent positioning of the Golgi

J Cell Sci

2013

Jaworski J

Uchwytny kształt pamięci

Biologia w szkole

Liszewska E, Jaworski J

Why do we need induced pluripotent stem cells in neurobiology?

Postepy Biochem

Lipka J, Kuijpers M,Jaworski J, Hoogenraad CC

Mutations in cytoplasmic dynein and its regulators cause malformations of cortical development and neurodegenerative diseases

Biochem Soc Trans

Janusz A, Milek J, Perycz M, Pacini L, Bagni C, Kaczmarek L, Dziembowska M

The fragile x mental retardation protein regulates matrix metalloproteinase 9 mRNA at synapses

J Neurosci

Bedzhov I, Alotaibi H, Basilicata MF, Ahlborn K,Liszewska E, Brabletz T, Stemmler MP

Adhesion, but not a specific cadherin code, is indispensable for ES cell and induced pluripotency

Stem Cell Res

Macias M, Blazejczyk M, Kazmierska P, Caban B, Skalecka A, Tarkowski B, Rodo A, Konopacki J, Jaworski J

Spatiotemporal Characterization of mTOR Kinase Activity Following Kainic Acid Induced Status Epilepticus and Analysis of Rat Brain Response to Chronic Rapamycin Treatment

PLoS One

Kapitein LC, van Bergeijk P, Lipka J, Keijzer N, Wulf PS, Katrukha EA, Akhmanova A, Hoogenraad CC

Myosin-V Opposes Microtubule-Based Cargo Transport and Drives Directional Motility on Cortical Actin

Curr Biol

Kuzniewska B, Rejmak E, Malik AR, Jaworski J, Kaczmarek L, Kalita K

Brain-derived neurotrophic factor induces matrix metalloproteinase-9 expression in neurons via serum response factor/c-Fos pathway

Mol Cell Biol

van Spronsen M, Mikhaylova M, Lipka J, Schlager MA, van den Heuvel DJ, Kuijpers M, Wulf PS, Keijzer N, Demmers J, Kapitein LC, Jaarsma D, Gerritsen HC, Akhmanova A, Hoogenraad CC

TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites

Neuron

Malik AR, Urbanska M, Gozdz A, Swiech LJ, Nagalski A, Perycz M, Blazejczyk M, Jaworski J

CYR61, a matricellular protein, is needed for dendritic arborization of hippocampal neurons

J Biol Chem

Malik AR, Urbanska M, Macias M, Skalecka A, Jaworski J

Beyond control of protein translation: What we have learned about the non-canonical regulation and function of mammalian target of rapamycin (mTOR)

Biochim Biophys Acta

2012

Knapska E, Macias M, Mikosz M, Nowak A, Owczarek D, Wawrzyniak M, Pieprzyk M, Cymerman IA, Werka T, Sheng M, Maren S, Jaworski J, Kaczmarek L

Functional anatomy of neural circuits regulating fear and extinction

Proc. Natl. Acad. Sci.

Urbanska M, Gozdz A, Swiech LJ, Jaworski J

Mammalian target of rapamycin complex 1 (MTORC1) and 2 MTORC2) control the dendritic arbor morphology of hippocampal neurons

JBC

Urbanska M, Swiech L, Jaworski J

Developmental plasticity of the dendritic compartment: focus on the cytoskeleton

Adv Exp Med Biol

2011

Werner M, Purta E, Kaminska KH, Cymerman IA, Campbell DA, Mittra B, Zamudio JR, Sturm NR, Jaworski J, Bujnicki JM

2'-O-ribose methylation of cap2 in human: function and evolution in a horizontally mobile family

Nucleic Acids Res

Kapitein LC, Yau KW, Gouveia SM, van der Zwan WA, Wulf PS, Keijzer N, Demmers J, Jaworski J, Akhmanova A, Hoogenraad CC

NMDA Receptor Activation Suppresses Microtubule Growth and Spine Entry

J Neurosci

Perycz M, Urbanska AS, Krawczyk PS, Parobczak K, Jaworski J

Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neurons

J Neurosci

Swiech L, Blazejczyk M, Urbanska M, Pietruszka P, Dortland BR, Malik AR, Wulf PS, Hoogenraad CC, Jaworski J

CLIP-170 and IQGAP1 cooperatively regulate dendrite morphology

J Neurosci

Azoulay-Alfaguter I, Yaffe Y, Licht-Murava A, Urbanska M, Jaworski J, Pietrokovski S, Hirschberg K, Eldar-Finkelman H

Distinct molecular regulation of glycogen synthase kinase-3alpha isozyme controlled by its N-terminal region: functional role in calcium/calpain signaling

J Biol Chem

2010

Piechota M, Korostynski M, Solecki W, Gieryk A, Slezak M, Bilecki W, Ziolkowska B, Kostrzewa E, Cymerman I, Swiech L, Jaworski J, Przewlocki R

The dissection of transcriptional modules regulated by various drugs of abuse in the mouse striatum.

Genome Biol

Kieper J, Lauber C, Gimadutdinow O, Urbańska A, Cymerman I, Ghosh M, Szczesny B, Meiss G

Production and characterization of recombinant protein preparations of Endonuclease G-homologs from yeast, C. elegans and humans.

Protein Expr Purif

Stefaniuk M, Swiech L, Dzwonek J, Lukasiuk K

Expression of Ttyh1, a member of the Tweety family in neurons in vitro and in vivo and its potential role in brain pathology.

J Neurochem

2009

Jaworski J, Kapitein LC, Gouveia SM, Dortland BR, Wulf PS, Grigoriev I, Camera P, Spangler SA, Di Stefano P, Demmers J, Krugers H, Defilippi P, Akhmanova A, Hoogenraad CC

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity.

Neuron

Blazejczyk M, Sobczak A, Debowska K, Wisniewska MB, Kirilenko A, Pikula S, Jaworski J, Kuznicki J, Wojda U.

Biochemical characterization and expression analysis of a novel EF-hand Ca2+ binding protein calmyrin2 (Cib2) in brain indicates its function in NMDA receptor mediated Ca2+ signaling.

Arch Biochem Biophys

2008

Tomat E, Nolan EM, Jaworski J, Lippard SJ

Organelle-specific zinc detection using zinpyr-labeled fusion proteins in live cells

J Am Chem Soc

Rylski M, Amborska R, Zybura K, Mioduszewska B, Michaluk P, Jaworski J, Kaczmarek L

Yin Yang 1 is a critical repressor of matrix metalloproteinase-9 expression in brain neurons

J Biol Chem

Jaworski J, Hoogenraad CC, Akhmanova A

Microtubule plus-end tracking proteins in differentiated mammalian cells.

Int J Biochem Cell Biol

Swiech L, Perycz M, Malik A, Jaworski J

Role of mTOR in physiology and pathology of the nervous system

Biochim Biophys Acta

Macias M

Injury induced dendritic plasticity in the mature central nervous system.

Acta Neurobiol Exp (Wars)

Urbanska M, Blazejczyk M, Jaworski J

Molecular basis of dendritic arborization

Acta Neurobiol Exp (Wars)

Mioduszewska B, Jaworski J, Szklarczyk AW, Klejman A, Kaczmarek L

Inducible cAMP early repressor (ICER)-evoked delayed neuronal death in the organotypic hippocampal culture

J Neurosci Res

2007

Jaworski J

ARF6 in the nervous system.

Eur J Cell Biol

Michaluk P, Kolodziej L, Mioduszewska B, Wilczynski GM, Dzwonek J, Jaworski J, Gorecki DC, Ottersen OP, Kaczmarek L

Beta-dystroglycan as a target for MMP-9, in response to enhanced neuronal activity.

J Biol Chem

Okulski P, Jay TM, Jaworski J, Duniec K, Dzwonek J, Konopacki FA, Wilczynski GM, Sánchez-Capelo A, Mallet J, Kaczmarek L

TIMP-1 abolishes MMP-9-dependent long-lasting long-term potentiation in the prefrontal cortex.

Biol Psychiatry

2006

Jaworski J, Sheng M

The growing role of mTOR in neuronal development and plasticity

Mol Neurobiol

Nolan EM, Ryu JW, Jaworski J, Feazell RP, Sheng M, Lippard SJ

Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization.

J Am Chem Soc

Szymczak S, Kalita K, Jaworski J, Mioduszewska B, Savonenko A, Markowska A, Merchenthaler I, Kaczmarek L

Increased estrogen receptor beta expression correlates with decreased spine formation in the rat hippocampus

Hippocampus