Publications

All publications

2018

Sokol AM, Uszczynska-Ratajczak B, Collins MM, Bazala M, Topf U, Lundegaard PR, Sugunan S, Guenther S, Kuenne C, Graumann J, Chan SSL, Stainier DYR, Chacinska A.

Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish.

PLoS Genet.

Kowalski L, Bragoszewski P, Khmelinskii A, Glow E, Knop M, Chacinska A.

Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins.

BMC Biol.

Topf U, Suppanz I, Samluk L, Wrobel L, Böser A, Sakowska P, Knapp B, Pietrzyk MK, Chacinska A, Warscheid B.

Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species.

Nat Commun.

2017

Gold VA, Chroscicki P, Bragoszewski P, Chacinska A.

Visualization of cytosolic ribosomes on the surface of mitochondria by electron cryo-tomography.

EMBO Rep.

Chacinska A.

Cell biology: Sort and destroy

Nature

Bragoszewski P, Turek M, Chacinska A.

Control of mitochondrial biogenesis and function by the ubiquitin-proteasome system

Open Biol

2016

Wasilewski M, Chojnacka K, Chacinska A

Protein trafficking at the crossroads to mitochondria

Biochim Biophys Acta

Wasilewski M, Chojnacka K, Chacinska A

Białka mitochondrialne – import, eksport, degradacja

Postępy Biochemii

Callegari S, Richter F, Chojnacka K, Jans DC, Lorenzi I, Pacheu-Grau D, Jakobs S, Lenz C, Urlaub H, Dudek J, Chacinska A, Rehling P

TIM29 is a subunit of the human carrier translocase required for protein transport

FEBS Lett

Turakhiya U, von der Malsburg K, Gold VA, Guiard B, Chacinska A, van der Laan M, Ieva R

Protein Import by the Mitochondrial Presequence Translocase in the Absence of a Membrane Potential

J Mol Biol

Wrobel L, Sokol AM, Chojnacka M, Chacinska A

The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly

Sci Rep

Topf U, Wrobel L, Chacinska A

Chatty Mitochondria: Keeping Balance in Cellular Protein Homeostasis

Trends Cell Biol

2015

Keatinge M, Bui H, Menke A, Chen YC, Sokol AM, Bai Q, Ellett F, Da Costa M, Burke D, Gegg M, Trollope L, Payne T, McTighe A, Mortiboys H, de Jager S, Nuthall H, Kuo MS, Fleming A, Schapira AH, Renshaw SA, Highley JR, Chacinska A, Panula P, Burton EA, O'Neill MJ, Bandmann O

Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death

Hum Mol Genet

Sakowska P, Jans DC, Mohanraj K, Riedel D, Jakobs S, Chacinska A

The oxidation status of Mic19 regulates MICOS assembly

Mol Cell Biol

Wrobel L, Topf U, Bragoszewski P , Wiese S, Sztolsztener ME , Oeljeklaus S, Varabyova A, Lirski M, Chroscicki P, Mroczek S, Januszewicz E, Dziembowski A, Koblowska M, Warscheid B, Chacinska A

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol

Nature

Bragoszewski P, Wasilewski M, Sakowska P, Gornicka A, Böttinger L, Qiu J, Wiedemann N, Chacinska A

Retro-translocation of mitochondrial intermembrane space proteins

Proc Natl Acad Sci U S A

Chojnacka M, Gornicka A, Oeljeklaus S, Warscheid B, Chacinska A

Cox17 is an auxiliary factor involved in the control of the mitochondrial contact site and cristae organizing system

J Biol Chem

Barchiesi A, Wasilewski M, Chacinska A, Tell G, Vascotto C

Mitochondrial translocation of APE1 relies on the MIA pathway

Nucleic Acids Res

2014

Ieva R, Schrempp SG, Opaliński L Wollweber F, Höß P, Heißwolf AK, Gebert M, Zhang Y, Guiard B, Rospert S, Becker T, Chacinska A, Pfanner N, van der Laan M

Mgr2 functions as lateral gatekeeper for preprotein sorting in the mitochondrial inner membrane

Mol Cell.

Gornicka A, Bragoszewski P, Chroscicki P, Wenz LS, Schulz C, Rehling P, Chacinska A

A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria

Mol Biol Cell

Melin J, Schulz C, Wrobel L, Bernhard O, Chacinska A, Jahn O, Schmidt B, Rehling P

Presequence recognition by the tom40 channel contributes to precursor translocation into the mitochondrial matrix

Mol Cell Biol

Sokol AM, Sztolsztener ME, Wasilewski M, Heinz E, Chacinska A

Mitochondrial protein translocases for survival and wellbeing

FEBS Lett

Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J

Uniform nomenclature for the mitochondrial contact site and cristae organizing system

J Cell Biol.

2013

Qiu J, Wenz LS, Zerbes RM, Oeljeklaus S, Bohnert M, Stroud DA, Wirth C, Ellenrieder L, Thornton N, Kutik S, Wiese S, Schulze-Specking A, Zufall N, Chacinska A, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N, Wiedemann N, Becker T

Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation

Cell

Varabyova A, Topf U, Kwiatkowska P, Wrobel L, Kaus-Drobek M, Chacinska A

Mia40 and MINOS act in parallel with Ccs1 in the biogenesis of mitochondrial Sod1

FEBS J

Bragoszewski P, Gornicka A, Sztolsztener ME, Chacinska A

The ubiquitin-proteasome system regulates mitochondrial intermembrane space proteins

Mol Cell Biol

Wrobel L, Trojanowska A, Sztolsztener ME, Chacinska A

Mitochondrial protein import: Mia40 facilitates Tim22 translocation into the inner membrane of mitochondria

Mol Biol Cell

Varabyova A, Stojanovski D, Chacinska A

Mitochondrial protein homeostasis

IUBMB Life

Sztolsztener ME, Brewinska A, Guiard B, Chacinska A

Disulfide bond formation: sulfhydryl oxidase ALR controls mitochondrial biogenesis of human MIA40

Traffic

2012

Böttinger L*, Gornicka A*, Czerwik T, Bragoszewski P, Loniewska-Lwowska A, Schulze-Specking A, Truscott KN, Guiard B, Milenkovic D, Chacinska A, *equally contributing first author

In vivo evidence for cooperation of Mia40 and Erv1 in the oxidation of mitochondrial proteins

Mol Biol Cell

Voegtle FN, Burkhart JM, Rao S, Gerbeth C, Hinrichs J, Martinou JC, Chacinska A, Sickmann A, Zahedi RP, Meisinger C

Intermembrane space proteome of yeast mitochondria

Mol Cell Proteomics

Bohnert M, Wenz LS, Zerbes RM, Horvath SE, Stroud DA, von der Malsburg K, Müller JM, Oeljeklaus S, Perschil I, Warscheid B, Chacinska A, Veenhuis M, van der Klei IJ, Daum G, Wiedemann N, Becker T, Pfanner N, van der Laan M

Role of MINOS in protein biogenesis of the mitochondrial outer membrane

Mol Biol Cell.

Stojanovski D, Bragoszewski P, Chacinska A

The MIA pathway: A tight bond between protein transport and oxidative folding in mitochondria

BBA-MOL CELL RES

2011

Milczarski P, Bolibok-Brągoszewska H, Myśków B, Stojałowski S, Heller-Uszyńska K, Góralska M, Brągoszewski P, Uszyński G, Kilian A, Rakoczy-Trojanowska M

A high density consensus map of rye (Secale cereale L.) based on DArT markers

PLoS One

Schulz C, Lytovchenko O, Melin J, Chacinska A, Guiard B, Neumann P, Ficner R, Jahn O, Schmidt B, Rehling P

Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex

J Cell Biol.

von der Malsburg K, Müller JM, Bohnert M, Oeljeklaus S, Kwiatkowska P, Becker T, Loniewska-Lwowska A, Wiese S, Rao S, Milenkovic D, Hutu DP, Zerbes RM, Schulze-Specking A, Meyer HE, Martinou JC, Rospert S, Rehling P, Meisinger C, Veenhuis M et all

Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis

Dev Cell.

Becker T, Wenz LS, Krüger V, Lehmann W, Müller JM, Goroncy L, Zufall N, Lithgow T, Guiard B, Chacinska A, Wagner R, Meisinger C, Pfanner N

The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins

J Cell Biol.