Wsystkie publikacje


Czeredys M.

Dysregulation of Neuronal Calcium Signaling via Store-Operated Channels in Huntington’s Disease.

Front Cell Dev Biol.

Bochtler M, Fernandes H.

DNA adenine methylation in eukaryotes: Enzymatic mark or a form of DNA damage?


Maksymowicz M, Miączyńska M, Banach-Orłowska M.

Clathrin- and dynamin-dependent endocytosis limits canonical NF-κB signaling triggered by lymphotoxin β receptor.

Cell Commun Signal.

NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M & Slusarczyk P.

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants.


Kupisz-Urbańska M, Broczek K, Galus K, Mossakowska M, Marcinowska-Suchowierska E.

Age-related differences in vitamin D status in Polish centenarians compared with 65-year-olds.

Pol Arch Intern Med

Xu G-L, Bochtler M.

Reversal of nucleobase methylation by dioxygenases.

Nat Chem Biol

Cendrowski J, Miaczynska M.

Splicing variants of an endocytic regulator, BMP2K, differentially control autophagic degradation in erythroid cells.


Malik D, Kobyłecki K, Krawczyk P, Poznański J, Jakielaszek A, Napiórkowska A, Dziembowski A, Tomecki R, Nowotny M.

Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine..

Nucleic Acids Res.

Sojka DR, Gogler-Pigłowska A, Klarzyńska K, Klimczak M, Zylicz A, Głowala-Kosińska M, Krawczyk Z, Scieglinska D.

HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells.

Cancers (Basel)

Stawowczyk E, Kawalec P, Kowalska-Duplaga K, Mossakowska M.

Productivity Loss Among Parents of Children With Inflammatory Bowel Diseases in Relation to Disease Activity and Patient's Quality of Life.

J Pediatr Gastroenterol Nutr.

Mleczko-Sanecka K, Silvestri L.

Cell-type-specific insights into iron regulatory processes.

Am J Hematol

Albert M-C, Brinkmann K, Pokrzywa W, Günther SD, Krönke M, Hoppe T, Kashkar H.

CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage.

Cell Death & Disease

Yang S, Emelyanov A, You MS, Sin M, Korzh V.

Camel regulates development of the brain ventricular system.

Cell Tissue Res.

Gupta RK, Wasilewska I, Palchevska O, Kuźnicki J.

Knockout of stim2a Increases Calcium Oscillations in Neurons and Induces Hyperactive-Like Phenotype in Zebrafish Larvae.

Int. J. Mol. Sci.

Fricke T, Smalakyte D, Lapinski M, Pateria A, Weige C, Pastor M, Kolano A, Winata C, Siksnys V, Tamulaitis G, Bochtler M.

Targeted RNA Knockdown by a Type III CRISPR-Cas Complex in Zebrafish.


Cendrowski J, Kaczmarek M, Mazur M, Kuzmicz-Kowalska K, Jastrzebski K, Brewinska-Olchowik M, Kominek A, Piwocka K, Miaczynska M.

Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells.


Lutz T, Czapinska H, Fomenkov A, Potapov V, Heiter DF, Cao B, Dedon P, Bochtler M, Xu S.

Protein Domain Guided Screen for Sequence Specific and Phosphorothioate-Dependent Restriction Endonucleases.

Front. Microbiol.

Wirecki TK, Merdas K, Bernat A, Boniecki MJ, Bujnicki JM, Stefaniak F.

RNAProbe: a web server for normalization and analysis of RNA structure probing data.

Nucleic Acids Res.

Ogórek B, Hamieh L, Hulshof HM, Lasseter K, Klonowska K, Kuijf H, Moavero R, Hertzberg C, Weschke B, Riney K, Feucht M, Scholl T, Krsek P, Nabbout R, Jansen AC, Benova B, Aronica E, Lagae L, Curatolo P, Borkowska J, Sadowski K, Domańska-Pakieła D, Janson S, Kozlowski P, Urbanska M, Jaworski J, Jozwiak S, Jansen FE, Kotulska K; EPISTOP Consortium members, Kwiatkowski DJ.

TSC2 pathogenic variants are predictive of severe clinical manifestations in TSC infants: results of the EPISTOP study.

Genet Med.

Grabowska W, Achtabowska N, Klejman A, Skowronek K, Calka M, Bielak-Zmijewska A.

IQGAP1-dysfunction leads to induction of senescence in human vascular smooth muscle cells.

Mech Ageing Dev.

Chen L, Olszewski MB, Kruithof-de MJ, Snaar-Jagalska BE.

Zebrafish Microenvironment Elevates EMT and CSC-Like Phenotype of Engrafted Prostate Cancer Cells.


Korzh V, Kondrychyn I.

Origin and development of circumventricular organs in living vertebrate.

Semin Cell Dev Biol.

Sequeiros-Borja CE, Surpeta B, Brezovsky J.

Recent advances in user-friendly computational tools to engineer protein function.

Briefings in Bioinformatics

Kuzniewska B, Cysewski D, Wasilewski M, Sakowska P, Milek J, Kulinski TM, Winiarski M, Kozielewicz P, Knapska E, Dadlez M, Chacinska A, Dziembowski A, Dziembowska M.

Mitochondrial protein biogenesis in the synapse is supported by local translation.


Gupta RK, Kuznicki J.

Biological and Medical Importance of Cellular Heterogeneity Deciphered by Single-Cell RNA Sequencing.


NCD Risk Factor Collaboration (Mossakowska M and Ślusarczyk P)

Repositioning of the global epicentre of non-optimal cholesterol.


Turek M, Piechota M, Shanmugam N, Niklewicz M, Kowalski K, Chacińska A, Pokrzywa W.

Nutritional status and fecundity are synchronised by muscular exopheresis.


Wasilewska I, Gupta RK, Wojtaś B, Palchevska O, Kuźnicki J.

stim2b Knockout Induces Hyperactivity and Susceptibility to Seizures in Zebrafish Larvae.


Babkiewicz E, Bazała M, Urban P, Maszczyk P, Markowska M, Gliwicz M.

The effects of temperature on the proxies of visual detection of Danio rerio larvae: observations from the optic tectum.

Biology Open

Pozniak M, Sokolowska-Wedzina A, Jastrzebski K, Szymczyk J, Porebska N, Krzyscik MA, Zakrzewska M, Miaczynska M, Otlewski J, Opalinski L.

FGFR1 Clustering With Engineered Tetravalent Antibody Improves the Efficiency and Modifies the Mechanism of Receptor Internalization.

Mol Oncol.

NCD Risk Factor Collaboration (Mossakowska M and Ślusarczyk P)

National Trends in Total Cholesterol Obscure Heterogeneous Changes in HDL and non-HDL Cholesterol and total-to-HDL Cholesterol Ratio: A Pooled Analysis of 458 Population-Based Studies in Asian and Western Countries.

Int J Epidemiol.

Dey K, Bazala MA, Kuznicki J.

Targeting mitochondrial calcium pathways as a potential treatment against Parkinson’s disease.

Cell Calcium

Kisiala M, Kowalska M, Pastor M, Korza HJ, Czapinska H, Bochtler M.

Restriction endonucleases that cleave RNA/DNAheteroduplexes bind dsDNA in A-like conformation.

Nucleic Acids Res.

Fatima A, Irmak D, Noormohammadi A, Rinschen MM, Das A, Leidecker O, Schindler C, Sánchez-Gaya V, Wagle P, Pokrzywa W, Hoppe T, Rada-Iglesias A, Vilchez D.

The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells.

Commun Biol.

Skowronek KJ, Bochtler M.

In Vitro Directed Evolution of a Restriction Endonuclease With More Stringent Specificity.

J Vis Exp

Miao Z et al. (Boniecki MJ, Bujnicki JM, Joshi A, Magnus M, Piatkowski P, Pluta R.)

RNA-Puzzles Round IV: 3D Structure Predictions of Four Ribozymes and Two Aptamers.


Chorostecki U, Molina M, Pryszcz LP, Gabaldón T.

MetaPhOrs 2.0: Integrative, Phylogeny-Based Inference of Orthology and Paralogy Across the Tree of Life.

Nucleic Acids Res.

Lambert AR, Hallinan JP, Werther R, Głów D, Stoddard BL.

Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition.


Bilska A, Kusio-Kobiałka M, Krawczyk PS, Gewartowska OTarkowski B, Kobyłecki K, Nowis D, Golab J, Gruchota J, Borsuk E, Dziembowski A, Mroczek S.

Immunoglobulin Expression and the Humoral Immune Response Is Regulated by the Non-Canonical poly(A) Polymerase TENT5C.

Nat Commun.

Kaus-Drobek M, Mücke N, Szczepanowski RH, Wedig T, Czarnocki-Cieciura M, Polakowska M, Herrmann H, Wysłouch-Cieszyńska A, Dadlez M.

Vimentin S-glutathionylation at Cys328 Inhibits Filament Elongation and Induces Severing of Mature Filaments in Vitro.


Szewczyk M, Malik D, Borowski LS, Czarnomska SD, Kotrys AV, Klosowska-Kosicka K, Nowotny M, Szczesny RJ.

Human REXO2 Controls Short Mitochondrial RNAs Generated by mtRNA Processing and Decay Machinery to Prevent Accumulation of Double-Stranded RNA.

Nucleic Acids Res.

Cozzuto L, Liu H, Pryszcz LP, Pulido TH, Delgado-Tejedor A, Ponomarenko J, Novoa EM.

MasterOfPores: A Workflow for the Analysis of Oxford Nanopore Direct RNA Sequencing Datasets

Front Genet.

Surpeta B, Sequeiros-Borja CE, Brezovsky J.

Dynamics, a Powerful Component of Current and Future in Silico Approaches for Protein Design and Engineering.

Int J Mol Sci.

Hyjek-Składanowska M, Vickers T, Napiórkowska A, Anderson B, Tanowitz M, Crooke ST, Liang XH, Seth PP, Nowotny M.

Origins of the increased affinity of phosphorothioate-modified therapeutic nucleic acids for proteins.

J Am Chem Soc.

Adusumilli L, Facchinello N, Teh C, Busolin G, Le MT, Yang H, Beffagna G, Campanaro S, Tam WL, Argenton F, Lim B, Korzh V, Tiso N.

miR-7 Controls the Dopaminergic/Oligodendroglial Fate through Wnt/β-catenin Signaling Regulation.


Hamann L, Szwed M, Mossakowska M, Chudek J, Puzianowska-Kuznicka M.

First Evidence for STING SNP R293Q Being Protective Regarding Obesity-Associated Cardiovascular Disease in Age-Advanced Subjects - A Cohort Study.

Immun Ageing

Tempes A, Weslawski J, Brzozowska A, Jaworski J.

Role of dynein-dynactin complex, kinesins, motor adaptors and their phosphorylation in dendritogenesis.

J Neurochem.

Magnus M, Antczak M, Zok T, Wiedemann J, Lukasiak P, Cao Y, Bujnicki JM, Westhof E, Szachniuk M, Miao Z.

RNA-Puzzles toolkit: a computational resource of RNA 3D structure benchmark datasets, structure manipulation, and evaluation tools.

Nucleic Acids Res.

 Miaczynska M, Munson M.

Membrane Trafficking: Vesicle Formation, Cargo Sorting and Fusion.

Mol Biol Cell.

Kedra M, Banasiak K, Kisielewska K, Wolinska-Niziol L, Jaworski J, Zmorzynska J.

TrkB hyperactivity contributes to brain dysconnectivity, epileptogenesis, and anxiety in zebrafish model of Tuberous Sclerosis Complex.

Proc Natl Acad Sci U S A.

Macnar JM, Szulc N, Kryś JD, Badaczewska-Dawid AE, Gront D.

Article BioShell 3.0: Library for Processing Structural Biology Data.


Bochtler M.

Arrhenius-law-governed homo- and heteroduplex dissociation.

Phys Rev E

Majewski L, Maciąg F, Boguszewski PM, Kuznicki J.

Transgenic Mice Overexpressing Human STIM2 and ORAI1 in Neurons Exhibit Changes in Behavior and Calcium Homeostasis but Show No Signs of Neurodegeneration.

Int. J. Mol. Sci.

Gruszczynska-Biegala J, Strucinska K, Maciag F, Majewski L, Sladowska M, Kuznicki J.

STIM Protein-NMDA2 Receptor Interaction Decreases NMDA-Dependent Calcium Levels in Cortical Neurons.


Szymańska E, Nowak P, Kolmus K, Cybulska M, Goryca K, Derezińska-Wołek E, Szumera-Ciećkiewicz A, Brewińska-Olchowik M, Grochowska A, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miączyńska M.

Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer.

EMBO Mol Med.

Jaciuk M, Swuec P, Gaur V, Kasprzak JM, Renault L, Dobrychłop M, Nirwal S, Bujnicki JM, Costa A, Nowotny M.

A combined structural and biochemical approach reveals translocation and stalling of UvrB on the DNA lesion as a mechanism of damage verification in bacterial nucleotide excision repair.

DNA Repair (Amst).

Thapa P, Shanmugam N, Pokrzywa W.

Ubiquitin Signaling Regulates RNA Biogenesis, Processing, and Metabolism.



Mohanraj K, Wasilewski M, Benincá C, Cysewski D, Poznanski J, Sakowska P, Bugajska Z, Deckers M, Dennerlein S, Fernandez-Vizarra E, Rehling P, Dadlez M, Zeviani M, Chacinska A.

Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7.

EMBO Mol Med.

Monteuuis G, Miścicka A, Świrski M, Zenad L, Niemitalo O, Wrobel L, Alam J, Chacinska A, Kastaniotis AJ, Kufel J.

Non-canonical translation initiation in yeast generates a cryptic pool of mitochondrial proteins.

Nucleic Acids Res.

Bondarchuk TV, Lozhko DM, Shalak VF, Fatalska A, Szczepanowski RH, Dadlez M,
Negrutskii BS, El'skaya AV.

The protein-binding N-terminal domain of human translation elongation factor 1Bβ possesses a dynamic α-helical structural organization.

Int J Biol Macromol.

Moysa A, Hammerschmid D, Szczepanowski RH, Sobott F, Dadlez M.

Enhanced oligomerization of full-length RAGE by synergy of the interaction of its domains.

Sci Rep.

Mazur M, Dymek B, Koralewski R, Sklepkiewicz P, Olejniczak S, Mazurkiewicz M, Piotrowicz M, Salamon M, Jędrzejczak K, Zagozdzon A, Czestkowski W, Matyszewski K, Borek B, Bartoszewicz A, Pluta E, Rymaszewska A, Mozga W, Stefaniak F, Dobrzański P, Dzwonek K, Golab J, Golebiowski A, Olczak J.

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases.

J Med Chem.

Sulej AA

Improving selectivity of DNA-RNA binding zinc finger using directed evolution.

BMC Res Notes.

Nowacka M, Boccaletto P, Jankowska E, Jarzynka T, Bujnicki JM, Dunin-Horkawicz S.

RRMdb – an evolutionary-oriented database of RNA recognition motif sequences.


de Crecy-Lagard V, Boccaletto P, Mangleburg C, Sharma P, Lowe T, Leidel S, Bujnicki JM.

Matching tRNA modifications in humans to their known and predicted enzymes.

Nucleic Acids Res.

Stasiewicz J, Mukherjee S, Nithin C, Bujnicki JM.

QRNAS: software tool for refinement of nucleic acid structures.

BMC Struct Biol.

The RNAcentral Consortium (Bujnicki JM, Boccaletto P)

RNAcentral: a hub of information for non-coding RNA sequences.

Nucleic Acids Res.

Wyskida M, Owczarek AJ, Chełmecka E, Szczerbowska I, Mossakowska M, Grodzicki T, Puzianowska-Kuźnicka M, Olszanecka-Glinianowicz M, Chudek J.

Parathyroid hormone response to different vitamin D levels in population-based old and very-old Polish cohorts.

Exp Gerontol.

Banach-Orłowska M, Wyszyńska R, Pyrzyńska B, Maksymowicz M, Gołąb J, Miączyńska M.

Cholesterol restricts lymphotoxin β receptor-triggered NF-κB signaling.

Cell Commun Signal.

Slyvka A, Zagorskaitė E, Czapinska H, Sasnauskas G, Bochtler M.

Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.

Nucleic Acids Res.

Radom M, Machnicka MA, Krwawicz J, Bujnicki JM, Formanowicz P

Petri net-based model of the human DNA base excision repair pathway.

PLoS One

Magnus M, Kappel K, Das R, Bujnicki JM

RNA 3D structure prediction guided by independent folding of homologous sequences.

BMC Bioinformatics

Majewski L, Wojtas B, Maciąg F, Kuznicki J.

Changes in Calcium Homeostasis and Gene Expression Implicated in Epilepsy in Hippocampi of Mice Overexpressing ORAI1.

Int J Mol Sci.

Gonzalez-Delgado LS, Walters-Morgan H, Salamaga B, Robertson AJ, Hounslow AM, Jagielska E, Sabała I, Williamson MP, Lovering AL, Mesnage S.

Two-site recognition of Staphylococcus aureus peptidoglycan by lysostaphin SH3b.

Nat Chem Biol.

Pac A, Tobiasz-Adamczyk B, Błędowski P, Skalska A, Szybalska A, Zdrojewski T, Więcek A, Chudek J, Michel JP, Grodzicki T.

Influence of Sociodemographic, Behavioral and Other Health-Related Factors on Healthy Ageing Based on Three Operative Definitions.

J Nutr Health Aging.

Puzianowska-Kuznicka M, Kuryłowicz A, Walkiewicz D, Borkowska J, Owczarz M, Olszanecka-Glinianowicz M, Wieczorowska-Tobis K, Skalska A, Szybalska A, Mossakowska M.

Obesity Paradox in Caucasian Seniors: Results of the PolSenior Study.

J Nutr Health Aging.

Soman SK, Bazała M, Keatinge M, Bandmann O, Kuznicki J.

Restriction of mitochondrial calcium overload by mcu inactivation renders neuroprotective effect in Zebrafish models of Parkinson's disease.

Biol Open.

Jędrychowska J, Korzh V.

Kv2.1 voltage‐gated potassium channels in developmental perspective.

Dev Dyn.

Gaur V, Ziajko W, Nirwal S, Szlachcic A, Gapińska M, Nowotny M

Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease.

Nucleic Acids Res.

Górecka KM, Krepl M, Szlachcic A, Poznański J, Šponer J, Nowotny M.

RuvC uses dynamic probing of the Holliday junction substrate to achieve sequence specificity and efficient resolution.

Nat Commun.

Lutz T, Flodman K, Copelas A, Czapinska H, Mabuchi M, Fomenkov A, He X, Bochtler M, Xu S.

A protein architecture guided screen for modification dependent restriction endonucleases.

Nucleic Acids Res.

Khalil R, Lalai RA, Wiweger MI, Avramut CM, Koster AJ, Spaink HP, Bruijn JA, Hogendoorn PCW, Baelde HJ.

Glomerular permeability is not affected by heparan sulfate glycosaminoglycan deficiency in zebrafish embryos.

Am J Physiol Renal Physiol.

Bulska-Będkowska W, Chełmecka E, Owczarek AJ, Mizia-Stec K, Witek A, Szybalska A, Grodzicki T, Olszanecka-Glinianowicz M, Chudek J.

CA125 as a Marker of Heart Failure in the Older Women: Population-Based Analysis.

J Clin Med

Królczyk J, Piotrowicz K, Chudek J, Puzianowska-Kuźnicka M, Mossakowska M, Szybalska A, Grodzicki T, Skalska A, Gąsowski J.

Clinical examination of peripheral arterial disease and ankle-brachial index in a nationwide cohort of older subjects: practical implications.

Aging Clin Exp Res

NCD Risk Factor Collaboration (Mossakowska M and Ślusarczyk P)

National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries.

Int J Epidemiol

Hyjek M, Figiel M, Nowotny M.

RNases H: Structure and mechanism.

DNA Repair (Amst)

Minhas R, Paterek A, Łapiński M, Bazała M, Korzh V, Winata CL

A novel conserved enhancer at zebrafish zic3 and zic6 loci drives neural expression.

Dev Dyn.

NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M and Ślusarczyk P

Rising rural body-mass index is the main driver of the global obesity epidemic in adults.


Klimczak M, Biecek P, Zylicz A, Zylicz M.

Heat shock proteins create a signature to predict the clinical outcome in breast cancer.

Sci Rep.

Samluk L, Urbanska M, Kisielewska K, Mohanraj K, Kim MJ, Machnicka K, Liszewska E, Jaworski J, Chacinska A.

Cytosolic translational responses differ under conditions of severe short-term and long-term mitochondrial stress.

Mol Biol Cell.

Nowacka M, Fernandes H, Kiliszek A, Bernat A, Lach G, Bujnicki JM.

Specific interaction of zinc finger protein Com with RNA and the crystal structure of a self-complementary RNA duplex recognized by Com.

PLoS One

McIntyre J, Sobolewska A, Fedorowicz M, McLenigan MP, Macias M, Woodgate R, Sledziewska-Gojska E.

DNA polymerase ι is acetylated in response to SN2 alkylating agents.

Sci Rep.

Czapinska H, Siwek W, Szczepanowski RH, Bujnicki JM, Bochtler M, Skowronek KJ.

Crystal Structure and Directed Evolution of Specificity of NlaIV Restriction Endonuclease.

J Mol Biol.

Wasilewska I, Gupta RK, Palchevska O, Kuźnicki J.

Identification of Zebrafish Calcium Toolkit Genes and their Expression in the Brain.

Genes (Basel)

Rojek KO, Krzemień J, Doleżyczek H, Boguszewski PM, Kaczmarek L, Konopka W, Rylski M, Jaworski J, Holmgren L, Prószyński TJ.

Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice.

PLoS Biol.

Mitkowski P, Jagielska E, Nowak E, Bujnicki JM, Stefaniak F, Niedziałek D, Bochtler M, Sabała I.

Structural bases of peptidoglycan recognition by lysostaphin SH3b domain.

Sci Rep.

Ahuja G et al. (Dodzian J)

Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.


Tarkowski B, Kuchcinska K, Blazejczyk M, Jaworski J.

Pathological mTOR mutations impact cortical development.

Hum Mol Genet.

Deskur-Śmielecka E, Chudek J, Neumann-Podczaska A, Mossakowska M, Wizner B, Wieczorowska-Tobis K.

Use of renal risk drugs in a nation-wide Polish older adult population: an analysis of PolSenior database.

BMC Geriatr.

Bizzarri M, Cassanelli S, Bartolini L, Pryszcz LP, Dušková M, Sychrová H, Solieri L.

Interplay of Chimeric Mating-Type Loci Impairs Fertility Rescue and Accounts for Intra-Strain Variability in Zygosaccharomyces rouxii Interspecies Hybrid ATCC42981.

Front Genet.

Pawełkowicz M, Pryszcz L, Skarzyńska A, Wóycicki RK, Posyniak K, Rymuszka J, Przybecki Z, Pląder W.

Comparative transcriptome analysis reveals new molecular pathways for cucumber genes related to sex determination.

Plant Reprod.

Kampingaa HH et al. …. (Zylicz A, Zylicz M)

Function, evolution, and structure of J-domain proteins.

Cell Stress Chaperones.

Olszewski MB, Pruszko M, Snaar-Jagalska E, Zylicz A, Zylicz M.

Diverse and cancer type‑specific roles of the p53 R248Q gain‑of‑function mutation in cancer migration and invasiveness.

Int. J. Oncol.

Olczak E, Kuryłowicz A, Wicik Z, Kołodziej P, Cąkała-Jakimowicz M, Buyanovskaya O, Ślusarczyk P, Mossakowska M, Puzianowska-Kuźnicka M.

Glucocorticoid receptor (NR3C1) gene polymorphisms are associated with age and blood parameters in Polish Caucasian nonagenarians and centenarians.

Exp Gerontol.

Pawlak M, Kedzierska KZ, Migdal M, Nahia KA, Ramilowski JA, Bugajski L, Hashimoto K, Marconi A, Piwocka K, Carninci P, Winata CL.

Dynamics of cardiomyocyte transcriptome and chromatin landscape demarcates key events of heart development.

Genome Res.

Maciąg F, Majewski Ł, Boguszewski P.M, Gupta R.K, Wasilewska I, Wojtas B, Kuznicki J.

Behavioral and electrophysiological changes in female mice overexpressing ORAI1 in neurons.

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Ponce-Salvatierra A, Astha, Merdas K, Chandran N, Ghosh P, Mukherjee S, Bujnicki JM.

Computational modeling of RNA 3D structure based on experimental data.

Biosci Rep.

Urbanska M⁠⁠,⁠ Kazmierska-Grebowska⁠ P, Kowalczyk⁠ T., Caban B⁠, Nader⁠ K, Pijet⁠ B, Kalita ⁠K, Gozdz⁠ A, Devijver⁠e H, Lechat⁠e B, Jaworski T⁠, Grajkowska⁠ W, Sadowski⁠ K, Jozwiak⁠ S⁠,⁠ Kotulska⁠ K, Konopacki⁠ J, Van Leuven⁠ F, van Vliet⁠h E⁠, Aronica⁠ E⁠,⁠ Jaworski⁠ J.

GSK3β activity alleviates epileptogenesis and limits GluA1 phosphorylation.


Grzeczkowicz A, Gruszczynska-Biegala J, Czeredys M, Kwiatkowska A, Strawski M, Szklarczyk M, Koźbiał M, Kuźnicki J, Granicka LH.

Polyelectrolyte Membrane Scaffold Sustains Growth of Neuronal Cells.

J Biomed Mater Res A.

Hamann L, Ruiz-Moreno JS, Szwed M, Mossakowska M, Lundvall L, Schumann RR, Opitz B, Puzianowska-Kuznicka M.

STING SNP R293Q Is Associated with a Decreased Risk of Aging-Related Diseases.


Firkowska M, Macias M, Jaworski J.

ESCRT Proteins Control the Dendritic Morphology of Developing and Mature Hippocampal Neurons.

Mol Neurobiol.

Rydzanicz M, Wachowska M, Cook EC, Lisowski P, Kuźniewska B, Szymańska K, Diecke S, Prigione A, Szczałuba K, Szybińska A, Koppolu A, Murcia Pienkowski V, Kosińska J, Wiweger M, Kostrzewa G, Brzozowska M, Domańska-Pakieła D, Jurkiewicz E, Stawiński P, Gromadka A, Zielenkiewicz P, Demkow U, Dziembowska M, Kuźnicki J, Creamer TP, Płoski R.

Novel calcineurin A (PPP3CA) variant associated with epilepsy, constitutive enzyme activation and downregulation of protein expression.

Eur J Hum Genet.


Bizzarri M, Cassanelli S, Pryszcz LP, Gawor J, Gromadka R, Solieri L.

Draft Genome Sequences of the Highly Halotolerant Strain Zygosaccharomyces rouxii ATCC 42981 and the Novel Allodiploid Strain Zygosaccharomyces sapae ATB301T Obtained Using the MinION Platform.

Microbiol Resour Announc.

Saus E, Willis JR, Pryszcz LP, Hafez A, Llorens C, Himmelbauer H, Gabaldón T.

nextPARS: parallel probing of RNA structures in Illumina.


Mróz TL, Eves-van den Akker S, Bernat A, Skarzyńska A, Pryszcz L, Olberg M, Havey MJ, Bartoszewski G.

Transcriptome Analyses of Mosaic (MSC) Mitochondrial Mutants of Cucumber in a Highly Inbred Nuclear Background.


Figiel M, Krepl M, Park S, Poznański J, Skowronek K, Gołąb A, Ha T, Šponer J, Nowotny M.

Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase.

J Biol Chem

Budick-Harmelin N, Miaczynska M.

Integration of the Endocytic System into the Network of Cellular Functions.

Prog Mol Subcell Biol.

De Assis GG, Gasanov EV, de Sousa MBC, Kozacz A, Murawska-Cialowicz E. Brain derived neutrophic factor, a link of aerobic metabolism to neuroplasticity.

Brain derived neutrophic factor, a link of aerobic metabolism to neuroplasticity.

J Physiol Pharmacol.

Brendel M, Jaworska A, Overhoff F, Blume T, Probst F, Gildehaus FJ, Bartenstein P, Haass C, Bohrmann B, Herms J, Willem M, Rominger A.

Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional Aβ deposition rate and plaque burden at treatment initiation.


Kuzniewska B, Sadowski K, Urbanska K, Urbanska M, Kotulska K, Liszewska E, Grajkowska W, Jóźwiak S, Dziembowska M.

The level of microRNA 21 is upregulated by rapamycin in serum of tuberous sclerosis complex patients and subependymal giant cell astrocytoma (SEGA)-derived cell cultures.

Folia Neuropathol.

Liszewska E, Jaworski J.

Neural Stem Cell Dysfunction in Human Brain Disorders.

Results Probl Cell Differ.

Jaworski J, Kalita K, Knapska E.

c-Fos and neuronal plasticity: the aftermath of Kaczmarek's theory.

Acta Neurobiol Exp (Wars).

Mazur M, Bartoszewicz A, Dymek B, Salamon M, Andryianau G, Kowalski M, Olejniczak S, Matyszewski K, Pluta E, Borek B, Stefaniak F, Zagozdzon A, Mazurkiewicz M, Koralewski R, Czestkowski W, Piotrowicz M, Niedziejko P, Gruza MM, Dzwonek K, Golebiowski A, Golab J, Olczak J.

Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase.


Bennabi I, Quéguiner I, Kolano A, Boudier T, Mailly P, Verlhac MH, Terret ME.

Shifting meiotic to mitotic spindle assembly in oocytes disrupts chromosome alignment.


Bochtler M, Mizgalska D, Veillard F, Nowak ML, Houston J, Veith P, Reynolds EC, Potempa J.

The Bacteroidetes Q-Rule: Pyroglutamate in Signal Peptidase I Substrates.

Front Microbiol.

Voigt C, Dobrychlop M, Kruse E, Czerwoniec A, Kasprzak JM, Bytner P, Campo CD, Leeder WM, Bujnicki JM, Göringer HU.

The OB-fold proteins of the Trypanosoma brucei editosome execute RNA-chaperone activity.

Nucleic Acids Res.

Jantsch MF et al. (Bujnicki J, Purta E)

Positioning Europe for the EPITRANSCRIPTOMICS challenge.

RNA Biol.

Toczydlowska-Socha D, Zielinska MM, Kurkowska M, Astha, Almeida CF, Stefaniak F, Purta E, Bujnicki JM.

Human RNA cap1 methyltransferase CMTr1 cooperates with RNA helicase DHX15 to modify RNAs with highly structured 5' termini.

Philos Trans R Soc Lond B Biol Sci.

Hareza A, Bakun M, Świderska B, Dudkiewicz M, Koscielny A, Bajur A, Jaworski J, Dadlez M, Pawłowski K.

Phosphoproteomic insights into processes influenced by the kinase-like protein DIA1/C3orf58.


Sokol AM, Uszczynska-Ratajczak B, Collins MM, Bazala M, Topf U, Lundegaard PR, Sugunan S, Guenther S, Kuenne C, Graumann J, Chan SSL, Stainier DYR, Chacinska A.

Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish.

PLoS Genet.

Tamulaitiene G, Manakova E, Jovaisaite V, Tamulaitis G, Grazulis S, Bochtler M, Siksnys V.

Unique mechanism of target recognition by PfoI restriction endonuclease of the CCGG-family.

Nucleic Acids Res.

Stroynowska-Czerwinska A, Piasecka A, Bochtler M.

Specificity of MLL1 and TET3 CXXC domains towards naturally occurring cytosine modifications.

Biochim Biophys Acta Gene Regul Mech.

Gutmajster E, Chudek J, Augusciak-Duma A, Szwed M, Szybalska A, Mossakowska M, Puzianowska-Kuznicka M, Wiecek A, Sieron AL.

Possible association of the TERT promoter polymorphisms rs2735940, rs7712562 and rs2853669 with diabetes mellitus in obese elderly Polish population: results from the national PolSenior study.

J Appl Genet.

Rewiuk K, Wizner B, Klich-Rączka A, Więcek A, Mossakowska M, Chudek J, Szybalska A, Broczek K, Zdrojewski T, Grodzicki T.

Atrial fibrillation independently linked with depression in communitydwelling older population. Results from the nationwide PolSenior project.

Exp Gerontol.


Winata CL, Korzh V.

Zebrafish Zic Genes Mediate Developmental Signaling.

Adv Exp Med Biol.

Kowalski L, Bragoszewski P, Khmelinskii A, Glow E, Knop M, Chacinska A.

Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins.

BMC Biol.

Topf U, Suppanz I, Samluk L, Wrobel L, Böser A, Sakowska P, Knapp B, Pietrzyk MK, Chacinska A, Warscheid B.

Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species.

Nat Commun.

Banach-Orłowska M, Jastrzębski K, Cendrowski JMaksymowicz M, Wojciechowska K, Korostyński M, Moreau D, Gruenberg J, Miaczynska M.

The topology of lymphotoxin β receptor accumulated upon endolysosomal dysfunction dictates the NF-κB signaling outcome.

J Cell Sci.

Czeredys M, Vigont VA, Boeva VA, Mikoshiba K, Kaznacheyeva EV, Kuznicki J.

Huntingtin-Associated Protein 1A Regulates Store-Operated Calcium Entry in Medium Spiny Neurons From Transgenic YAC128 Mice, a Model of Huntington’s Disease.

Front Cell Neurosci.

Fernandes H, Czapinska H, Grudziaz K, Bujnicki JM, Nowacka M.

Crystal structure of human Acinus RNA recognition motif domain.


Nithin C, Ghosh P, Bujnicki JM.

Bioinformatics Tools and Benchmarks for Computational Docking and 3D Structure Prediction of RNA-Protein Complexes.

Genes (Basel)

Styszynski A, Mossakowska M, Chudek J, Puzianowska-Kuznicka M, Klich-Raczka A, Neumann-Podczaska A, Szybalska A, Wieczorowska-Tobis K.

Prevalence of anemia in relation to socio-economic factors in elderly Polish population: the results of PolSenior study.

J Physiol Pharmacol.

Walerych D, Pruszko M, Zyla L, Wezyk M, Gaweda-Walerych K, Zylicz A.

Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanism.


Mehr K, Olszanecka-Glinianowicz M, Chudek J, Szybalska A, Mossakowska M, Zejda J, Wieczorowska-Tobis K, Grodzicki T, Piotrowski P.

Dental status in the Polish senior population and its correlates-Results of the national survey PolSenior.


Kisiala M, Copelas A, Czapinska H, Xu S, Bochtler M.

Crystal structure of the modification-dependent SRA-HNH endonuclease TagI

Nucleic Acids Res.

Kumari P, Aeschimann F, Gaidatzis D, Keusch JJ, Ghosh P, Neagu A, Pachulska-Wieczorek K, Bujnicki JM, Gut H, Großhans H, Ciosk R.

Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.

Nat Commun.

Foik IP, Tuszynska I, Feder M, Purta E, Stefaniak F, Bujnicki JM.

Novel inhibitors of the rRNA ErmC' methyltransferase to block resistance to macrolides, lincosamides, streptogramine B antibiotics.

Eur J Med Chem.

Czapinska H, Kowalska M, Zagorskaite E, Manakova E, Slyvka A, Xu SY, Siksnys V, Sasnauskas G, Bochtler M.

Activity and structure of EcoKMcrA.

Nucleic Acids Res.

Pluta R, Espinosa M.

Antisense and yet sensitive: Copy number control of rolling circle-replicating plasmids by small RNAs.

Wiley Interdiscip Rev RNA

Szybalska A, Broczek K, Puzianowska-Kuznicka M, Slusarczyk P, Chudek J, Skalska A, Mossakowska M.

Self-rated health and its association with all-cause mortality of older adults in Poland: The PolSenior project.

Arch Gerontol Geriatr.

Wegierski T, Kuznicki J.

Neuronal calcium signaling via store-operated channels in health and disease.

Cell Calcium.

Winata CL, Korzh V.

The translational regulation of maternal mRNAs in time and space.

FEBS Lett.

Koyuncu S, Saez I, Lee HJ, Gutierrez-Garcia R, Pokrzywa W, Fatima A, Hoppe T, Vilchez D.

The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients.

Nat Commun.

Kocełak P, Owczarek A, Bożentowicz-Wikarek M, Brzozowska A, Mossakowska M, Grodzicki T, Więcek A, Chudek J, Olszanecka-Glinianowicz M.

Plasma concentration of Retinol Binding Protein 4 (RBP4) in relation to nutritional status and kidney function in older population of PolSenior Study.

Adv Med Sci.

Majerczyk M, Choręza P, Mizia-Stec K, Bożentowicz-Wikarek M, Brzozowska A, Arabzada H, Owczarek AJ, Szybalska A, Grodzicki T, Więcek A, Olszanecka-Glinianowicz M, Chudek J.

Plasma Level of Retinol-Binding Protein 4, N-Terminal proBNP and Renal Function in Older Patients Hospitalized for Heart Failure.

Cardiorenal Med.

Donzelli S, Milano E, Pruszko M, Sacconi A, Masciarelli S, Iosue I, Melucci E, Gallo E, Terrenato I, Mottolese M, Zylicz M, Zylicz A, Fazi F, Blandino G, Fontemaggi G.

Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages.

Breast Cancer Res.

Szybalska A, Broczek K, Slusarczyk P, Kozdron, Chudek J, Puzianowska‑Kuznicka M, Kostka T, Skalska A, Mossakowska M.

Utilization of medical rehabilitation services among older Poles: results of the PolSenior study.

Eur Geriatr Med.

Pawlak M, Niescierowicz K, Winata CL.

Decoding the Heart through Next Generation Sequencing Approaches.

Genes (Basel).

Hadar A, Milanesi E, Walczak M, Puzianowska-Kuźnicka M, Kuźnicki J, Squassina A, Niola P, Chillotti C, Attems J, Gozes I, Gurwitz D.

SIRT1, miR-132 and miR-212 link human longevity to Alzheimer's Disease.

Sci Rep.

Jurcik A, Bednar D, Byska J, Marques SM, Furmanova K, Daniel L, Kokkonen P, Brezovsky J, Strnad O, Stourac J, Pavelka A, Manak M, Damborsky J, Kozlikova B.

CAVER Analyst 2.0: Analysis and Visualization of Channels and Tunnels in Protein Structures and Molecular Dynamics Trajectories.


Wojtczak BA, Sikorski PJ, Fac-Dabrowska K, Nowicka A, Warminski M, Kubacka D, Nowak E, Nowotny M, Kowalska J, Jemielity J.

5′-Phosphorothiolate Dinucleotide Cap Analogues: Reagents for Messenger RNA Modification and Potent Small-Molecular Inhibitors of Decapping Enzymes.

J Am Chem Soc.

Dodzian J, Kean S, Seidel J, Valenzano DR.

A Protocol for Laboratory Housing of Turquoise Killifish (Nothobranchius furzeri).

Journal of Visualized Experiments (JoVE)

Holko P, Kawalec P, Mossakowska M.

Quality of life related to oral, subcutaneous, and intravenous biologic treatment of inflammatory bowel disease: a time trade-off study.

J Gastroenterol Hepatol

NCD Risk Factor Collaboration (Mossakowska M and Slusarczyk P)

Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants.

Int J Epidemiol.

Szybalska A, Broczek K, Ślusarczyk P, Kozdroń E, Błędowski P, Chudek J, Mossakowska M.

The utilization of health resort treatment services by older people in Poland – results of the PolSenior study.

Gerontologia Polska

Balaji V, Pokrzywa W, Hoppe T.

Ubiquitylation Pathways In Insulin Signaling and Organismal Homeostasis.


Wawrzynow B, Zylicz A, Zylicz M.

Chaperoning the guardian of the genome. The two-faced role of molecular chaperones in p53 tumor suppressor action.

BBA-Rev Cancer

Majerczyk M, Kocełak P, Choręza P, Arabzada H, Owczarek AJ, Bożentowicz-Wikarek M, Brzozowska A, Szybalska A, Puzianowska-Kuźnicka M, Grodzicki T, Więcek A, Olszanecka-Glinianowicz M, Chudek J.

Components of metabolic syndrome in relation to plasma levels of retinol binding protein 4 (RBP4) in a cohort of people aged 65 years and older.

J Endocrinol Invest.

Piasecka A, Czapinska H, Vielberg MT, Szczepanowski RH, Kiefersauer R, Reed S, Groll M, Bochtler M.

The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers.

J Mol Biol.

Boccaletto P, Machnicka MA, Purta E, Piatkowski P, Baginski B, Wirecki TK, de Crécy-Lagard V, Ross R, Limbach PA, Kotter A, Helm M, Bujnicki JM.

MODOMICS: a database of RNA modification pathways. 2017 update.

Nucleic Acids Res.

Wyskida M, Owczarek A, Szybalska A, Brzozowska A, Szczerbowska I, Wieczorowska-Tobis K, Puzianowska-Kuźnicka M, Franek E, Mossakowska M, Grodzicki T, Więcek A, Olszanecka-Glinianowicz M, Chudek J.

Socio-economic determinants of vitamin D deficiency in the older Polish population: results from the PolSenior study.

Public Health Nutr.

Razew M, Warkocki Z, Taube M, Kolondra A, Czarnocki-Cieciura M, Nowak E, Labedzka-Dmoch K, Kawinska A, Piatkowski J, Golik P, Kozak M, Dziembowski A, Nowotny M.

Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components.

Nat Commun.

Sulicka J, Pac A, Puzianowska-Kuźnicka M, Zdrojewski T, Chudek J, Tobiasz-Adamczyk B, Mossakowska M, Skalska A, Więcek A, Grodzicki T.

Health status of older cancer survivors—results of the PolSenior study.

Journal of Cancer Survivorship

Winata CL, Łapiński M, Pryszcz L, Vaz C, Bin Ismail MH, Nama S, Hajan HS, Lee SGP, Korzh V, Sampath P, Tanavde V, Mathavan S.

Cytoplasmic polyadenylation-mediated translational control of maternal mRNAs directs maternal to zygotic transition.


Gogler-Pigłowska A, Klarzyńska K, Sojka DR, Habryka A, Głowala-Kosińska M, Herok M, Kryj M, Halczok M, Krawczyk Z, Scieglinska D.

Novel role for the testis-enriched HSPA2 protein in regulating epidermal keratinocyte differentiation.

J Cell Physiol.

Urbanska M, Gozdz A, Macias M, Cymerman IA, Liszewska E, Kondratiuk I, Devijver H, Lechat B, Van Leuven F, Jaworski J.

GSK3β Controls mTOR and Prosurvival Signaling in Neurons.

Mol Neurobiol.

Boccaletto P, Magnus M, Almeida C, Zyla A, Astha A, Pluta R, Baginski B, Jankowska E, Dunin-Horkawicz S, Wirecki TK, Boniecki MJ, Stefaniak F, Bujnicki JM.

RNArchitecture: a database and a classification system of RNA families, with a focus on structural information.

Nucleic Acids Res.

Korzh V

Development of brain ventricular system

Cell Mol Life Sci

Koscielny A, Malik AR, Liszewska E, Zmorzynska J, Tempes A, Tarkowski B, Jaworski J

Adaptor Complex 2 Controls Dendrite Morphology via mTOR-Dependent Expression of GluA2

Mol Neurobiol


Jurkiewicz  D, Michalec  K, Skowronek  K, Nałęcz  KA.

Tight junction protein ZO-1 controls organic cation/carnitine transporter OCTN2 (SLC22A5) in a protein kinase C-dependent way.

Biochim Biophys Acta Mol Cell Res.

García-Lecea M, Gasanov E, Jedrychowska J, Kondrychyn I, Teh C, You MS, Korzh V.

Development of Circumventricular Organs in the Mirror of Zebrafish Enhancer-Trap Transgenics.

Front Neuroanat.

Woźniak A, Grześkowiak BF, Babayevska N, Zalewski T, Drobna M, Woźniak-Budych M, Wiweger M, Słomski R, Jurga S.

ZnO@Gd2O3 core/shell nanoparticles for biomedical applications: Physicochemical, in vitro and in vivo characterization.

Mater Sci Eng C Mater Biol Appl.

Slyvka A, Mierzejewska K, Bochtler M.

Nei-like 1 (NEIL1) excises 5-carboxylcytosine directly and stimulates TDG-mediated 5-formyl and 5-carboxylcytosine excision.

Sci Rep.

Gazda K, Bazała M, Węgierski T.

Mikroskopowe obrazowanie jonów wapnia za pomocą genetycznie kodowanych sond (Microscopic imaging of calcium ions with genetically encoded calcium indicators).

Postepy Biochem.

Dzananovic E, Astha, Chojnowski G, Deo S, Booy EP, Padilla-Meier P, McEleney K, Bujnicki JM, Patel TR, McKenna SA.

Impact of the structural integrity of the three-way junction of adenovirus VAI RNA on PKR inhibition.

PLoS One

Chawla M, Chermak E, Zhang Q, Bujnicki JM, Oliva R, Cavallo L.

Occurrence and stability of lone pair-π stacking interactions between ribose and nucleobases in functional RNAs.

Nucleic Acids Res.

Piątkowski P, Jabłońska J, Żyła A, Niedziałek, Matelska D, Jankowska E, Waleń T, Dawson WK, Bujnicki JM.

SupeRNAlign: a new tool for flexible superposition of homologous RNA structures and inference of accurate structure-based sequence alignments.

Nucleic Acids Res.

Mazurek T, Kobylecka M, Zielenkiewicz M, Kurek A, Kochman J, Filipiak KJ, Mazurek K, Huczek Z, Królicki L, Opolski G.

PET/CT evaluation of 18F-FDG uptake in pericoronary adipose tissue in patients with stable coronary artery disease: Independent predictor of atherosclerotic lesions' formation?

J Nucl Cardiol

Brendel M, Focke C, Blume T, Peters F, Deussing M, Probst F, Jaworska A, Overhoff F, Albert N, Lindner S, von Ungern-Sternberg B, Bartenstein P, Haass C, Kleinberger G, Herms J, Rominger A.

Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study.

J Nucl Med.

Majewski Ł, Maciąg F, Boguszewski PM, Wasilewska I, Wiera G, Wójtowicz T, Mozrzymas J, Kuznicki J.

Overexpression of STIM1 in neurons in mouse brain improves contextual learning and impairs long-term depression.

Biochim Biophys Acta

Gold VA, Chroscicki P, Bragoszewski P, Chacinska A.

Visualization of cytosolic ribosomes on the surface of mitochondria by electron cryo-tomography.


Szymanska E, Budick-Harmelin N, Miaczynska M.

Endosomal "sort" of signaling control: The role of ESCRT machinery in regulation of receptor-mediated signaling pathways.

Semin Cell Dev Biol.

Holko P, Kawalec P, Mossakowska M.

Quality of life related to oral, subcutaneous, and intravenous biologic treatment of inflammatory bowel disease: a time trade-off study.

Eur J Gastroenterol Hepatol.

Gazda K, Kuznicki J, Wegierski T.

Knockdown of amyloid precursor protein increases calcium levels in the endoplasmic reticulum.

Sci Rep

Pokrzywa W, Hoppe T.

CHIPped balance of proteostasis and longevity.


NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M & Slusarczyk P.

Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults.


Pasricha SR, Lim PJ, Duarte TL, Casu C, Oosterhuis D, Mleczko-Sanecka K, Suciu M, Da Silva AR, Al-Hourani K, Arezes J, McHugh K, Gooding S, Frost JN, Wray K, Santos A, Porto G, Repapi E, Gray N, Draper SJ, Ashley N, Soilleux E, Olinga P, Muckenthaler MU, Hughes JR, Rivella S, Milne TA, Armitage AE, Drakesmith H.

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

Nat Commun

Piven OO, Winata CL

The canonical way to make a heart: β-catenin and plakoglobin in heart development and remodeling

Experimental Biology and Medicine

Charbonnel C, Niazi AK, Elvira-Matelot E, Nowak E, Zytnicki M, de Bures A, Jobet E, Opsomer A, Shamandi N, Nowotny M, Carapito C, Reichheld J-P, Vaucheret H, Saez-Vasquez J.

The siRNA suppressor RTL1 is redox-regulated through glutathionylation of a conserved cysteine in the double-stranded-RNA-binding domain.

Nucleic Acids Res.

Rydzik AM, Warminski M, Sikorski PJ, Baranowski MR, Walczak S, Kowalska J, Zuberek J, Lukaszewicz M, Nowak E, W Claridge TD, Darzynkiewicz E, Nowotny M, Jemielity J.

mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.

Nucleic Acids Res.

Rydzik AM, Warminski M, Sikorski PJ, Baranowski MR, Walczak S, Kowalska J, Zuberek J, Lukaszewicz M, Nowak E, W Claridge TD, Darzynkiewicz E, Nowotny M, Jemielity J.

mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.

Nucleic Acids Res.

Szybinska A, Lesniak W

P53 Dysfunction in Neurodegenerative Diseases – The Cause or Effect of Pathological Changes?

Aging Dis.

Łabuz-Roszak B, Machowska-Majchrzak A, Skrzypek M, Mossakowska M, Chudek J, Więcek A, Wawrzyńczyk M, Łącka-Gaździk B, Pierzchała K

Antiplatelet and anticoagulant therapy in elderly people with type 2 diabetes mellitus in Poland (based on the PolSenior Study)

Arch Med Sci

Shen H, Shin EM, Lee S, Mathavan S, Koh H, Osato M, Choi H, Tergaonkar V, Korzh V

Ikk2 regulates cytokinesis during vertebrate development

Sci Rep

Figiel M, Nowotny M

Chapter Six - Structural Studies of RNases H2 as an Example of Crystal Structure Determination of Protein–Nucleic Acid Complexes

Methods in Enzymology

Figiel M, Krepl M, Poznanski J, Golab A, Šponer J, Nowotny M

Coordination between the polymerase and RNase H activity of HIV-1 reverse transcriptase

Nucleic Acids Res.

Pokrzywa W, Lorenz R, Hoppe T

Chaperone-directed ubiquitylation maintains proteostasis at the expense of longevity.

Worm (in press)

Łabuz-Roszak B, Skrzypek M, Machowska-Majchrzak A, Mossakowska M, Chudek J, Więcek A, Pierzchała K, Łącka-Gaździk B, Grodzicki T

Pharmacological stroke prevention in the elderly with atrial fibrillation in Poland - Results of PolSenior study

Neurol Neurochir Pol

Klimczak M, Czerwińska P, Mazurek S, Sozańska B, Biecek P, Mackiewicz A, Wiznerowicz M

TRIM28 epigenetic corepressor is indispensable for stable induced pluripotent stem cell formation

Stem Cell Research

Mleczko-Sanecka K, da Silva AR, Call D, Neves J, Schmeer N, Damm G, Seehofer D, Muckenthaler MU

Imatinib and spironolactone suppress hepcidin expression


Gozdz A, Nikolaienko O, Urbanska M, Cymerman IA, Sitkiewicz E, Blazejczyk M, Dadlez M, Bramham CR, Jaworski J

GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation

Front Mol Neurosci

Kevei É, Pokrzywa W, Hoppe T

Repair or Destruction: An Intimate Liaison Between Ubiquitin Ligases and Molecular Chaperones in Proteostasis

FEBS Lett. doi:10.1002/1873-3468.12750.

Koh CH, Wu J, Chung YY, Liu Z, Zhang RR, Chong K, Korzh V, Ting S, Oh S, Shim W, Tian HY, Wei H

Identification of a Na+/K+-ATPase inhibition-independent proarrhythmic ionic mechanisms of cardiac glycosides

Sci Rep.

Tan SY, Teh C, Ang CY, Li M, Li P, Korzh V, Zhao Y

Responsive mesoporous silica nanoparticles for sensing of hydrogen peroxide and simultaneous treatment toward heart failure


Owczarz M, Budzinska M, Domaszewska-Szostek A, Borkowska J, Polosak J, Gewartowska M, Slusarczyk P, Puzianowska-Kuznicka M

miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans

Experimental Biology and Medicine

Tracz-Gaszewska Z, Klimczak M, Biecek P, Herok M, Kosinski M, Olszewski MB, Czerwińska P, Wiech M, Wiznerowicz M, Zylicz A, Zylicz M, Wawrzynow B

Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation


Pruszko M, Milano E, Forcato M, Donzelli S, Ganci F, Di Agostino S, De Panfilis S, Fazi F, Bates DO, Bicciato S, Zylicz M, Zylicz A, Blandino G, Fontemaggi G

The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1


Budzko L, Jackowiak P, Kamel K, Sarzynska J, Bujnicki JM, Figlerowicz M

Mutations in human AID differentially affect its ability to deaminate cytidine and 5-methylcytidine in ssDNA substrates in vitro

Sci Rep

Karlowicz A, Wegrzyn K, Gross M, Kaczynska D, Ropelewska M, Siemiątkowska M, Bujnicki JM, Konieczny I

Defining the crucial domain and amino acid residues in bacterial Lon protease for DNA binding and processing of DNA-interacting substrates

J Biol Chem

Miao Z, Adamiak RW, Antczak M, Batey RT, Becka A, Biesiada M, Boniecki MJ, Bujnicki JM, Chen S, Cheng CY, Chou F, Ferré-D'Amaré AR, Das R, Dawson WK, Ding F, Dokholyan NV, Dunin-Horkawicz S, Geniesse C, Kappel K, Kladwang W, Krokhotin A, Lach GE, Major F, Mann TH, Magnus M, Pachulska-Wieczorek K, Patel DJ, Piccirilli JA, Popenda M, Purzycka KJ, Ren A, Rice GM, Santalucia J Jr, Sarzynska J, Szachniuk M, Tandon A, Trausch JJ, Tian S, Wang J, Weeks KM, Williams B II, Xiao Y, Xu X, Zhang D, Zok T, Westhof E

RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme


Urbanska AS, Janusz-Kaminska A, Switon K, Hawthorne AL, Perycz M, Urbanska M, Bassell GJ, Jaworski J

ZBP1 phosphorylation at serine 181 regulates its dendritic transport and the development of dendritic trees of hippocampal neurons

Sci Rep

de Hoz L, Gierej D, Lioudyno V, Jaworski J, Blazejczyk M, Cruces-Solís H, Beroun A, Lebitko T, Nikolaev T, Knapska E, Nelken I, Kaczmarek L

Blocking c-Fos Expression Reveals the Role of Auditory Cortex Plasticity in Sound Frequency Discrimination Learning

Cereb Cortex

Kononenko NL, Claßen GA, Kuijpers M, Puchkov D, Maritzen T, Tempes A, Malik AR, Skalecka A, Bera S, Jaworski J, Haucke V

Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration

Nat Commun

Chacinska A.

Cell biology: Sort and destroy


Bragoszewski P, Turek M, Chacinska A.

Control of mitochondrial biogenesis and function by the ubiquitin-proteasome system

Open Biol

Aksoy I, Utami KH, Winata CL, Hillmer AM, Rouam SL, Briault S, Davila S, Stanton LW, Cacheux V

Personalized genome sequencing coupled with iPSC technology identifies GTDC1 as a gene involved in neurodevelopmental disorders

Hum Mol Genet

Kawalec P, Stawowczyk E, Mossakowska M, Pilc A

Disease activity, quality of life, and indirect costs of ulcerative colitis in Poland

Prz Gastroenterol

Nagaraj S, Laskowska-Kaszub K, Dębski KJ, Wojsiat J, Dąbrowski M, Gabryelewicz T, Kuźnicki J, Wojda U

Profile of 6 microRNA in blood plasma distinguish early stage Alzheimer's disease patients from non-demented subjects


Brendel M, Kleinberger G, Probst F, Jaworska A, Overhoff F, Blume T, Albert NL, Carlsen J, Lindner S, Gildehaus FJ, Ozmen L, Suárez-Calvet M, Bartenstein P, Baumann K, Ewers M, Herms J, Haass C, Rominger A

Increase of TREM2 during Aging of an Alzheimer’s Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis

Front. Aging Neurosci.

Majerczyk M, Choręza P, Bożentowicz-Wikarek M, Brzozowska A, Arabzada H, Owczarek A, Mossakowska M, Grodzicki T, Zdrojewski T, Więcek A, Olszanecka-Glinianowicz M, Chudek J

Increased plasma RBP4 concentration in older hypertensives is related to the decreased kidney function and the number of antihypertensive drugs-results from the PolSenior substudy

J Am Soc Hypertens

NCD Risk Factor Collaboration (Mossakowska M and Slusarczyk P)

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants


Jastrzębski K, Zdżalik-Bielecka D, Mamińska A, Kalaidzidis Y, Hellberg C, Miaczynska M

Multiple routes of endocytic internalization of PDGFRβ contribute to PDGF-induced STAT3 signaling

J Cell Sci.

Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J

Molecular neurobiology of mTOR


Perycz M, Krwawicz J, Bochtler M.

A TALE-inspired computational screen for proteins that contain approximate tandem repeats.

PLoS One

Patel T, Chojnowski G, Astha, Koul A, McKenna S, Bujnicki JM

Structural studies of RNA-protein complexes: A hybrid approach involving hydrodynamics, scattering and computational methods


Soman S, Keatinge M, Moein M, DaCosta M, Mortiboys H, Skupin A, Sugunan S, Bazala M, Kuznicki J, Bandmann O

Inhibition of the mitochondrial calcium uniporter (MCU) rescues dopaminergic neurons in pink1-/- zebrafish

Eur J Neurosci.

Misztal K, Brozko N, Nagalski A, Szewczyk LM, Królak M, Brzozowska K, Kuznicki J, Wisniewska MB

TCF7L2 mediates the cellular and behavioral response to chronic lithium treatment in animal models


Gross B, Pawlak M, Lefebvre P, Staels B.


Nat Rev Endocrinol TEST

Czeredys M, Maciag F, Methner A, Kuznicki J

Tetrahydrocarbazoles decrease elevated SOCE in medium spiny neurons from transgenic YAC128 mice, a model of Huntington's disease

Biochem Biophys Res Commun

Szewczyk LM, Brozko N, Nagalski A, Rӧckle I, Werneburg S, Hildebrandt H, Wisniewska MB, Kuznicki J free access

ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons


Blazejczyk M, Macias M, Korostynski M, Firkowska M, Piechota M, Skalecka A, Tempes A, Koscielny A, Urbanska M, Przewlocki R, Jaworski J

Kainic Acid Induces mTORC1-Dependent Expression of Elmo1 in Hippocampal Neurons

Mol Neurobiol

Kondratiuk I, Łęski S, Urbańska M, Biecek P, Devijver H, Lechat B, Van Leuven F, Kaczmarek L, Jaworski T

GSK-3β and MMP-9 Cooperate in the Control of Dendritic Spine Morphology

Mol Neurobiol


Grulich M, Brezovský J, Štěpánek V, Palyzová A, Marešová H, Zahradník J, Kyslíková E, Kyslík P.

In-silico driven engineering of enantioselectivity of a penicillin G acylase towards active pharmaceutical ingredients.

J Mol Catal B Enzym

Głów D, Nowacka M, Skowronek KJ, Bujnicki JM.

Sequence-specific endoribonucleases.

Postępy Biochemii

Kędra M, Jaworski J, Zmorzyńska J.

Okiem ryby - nowe spojrzenie na rozwój sieci neuronalnych i choroby neurorozwojowe.


Olszewski M, Pruszko M.

Danio pręgowany jako organizm modelowy.


Pruszko M, Żylicz A.

Białka z rodziny ID w inicjacji i progresji nowotworów (Białka z rodziny ID w inicjacji i progresji nowotworów).

Postępy Biochemii

Goś D, Szymańska E, Białek-Wyrzykowska U, Wiweger M, Kuźnicki J.

Be Healthy as a Fish Educational Program at the International Institute of Molecular and Cell Biology in Warsaw, Poland.


Holko P, Kawalec P, Mossakowska M, Pilc A

Health-Related Quality of Life Impairment and Indirect Cost of Crohn's Disease: A Self-Report Study in Poland

PLoS One

Dawson WK, Maciejczyk M, Jankowska EJ, Bujnicki JM

Coarse-grained modeling of RNA 3D structure


Machnicka MA, Dunin-Horkawicz S, de Crécy-Lagard V, Bujnicki JM

tRNAmodpred: A computational method for predicting posttranscriptional modifications in tRNAs


Urulangodi M, Dhanaraju R, Gupta K, Roy RP, Bujnicki JM, Rao DN

Asymmetric DNA methylation by dimeric EcoP15I DNA methyltransferase


Pawlowski M, Kozlowski L, Kloczkowski A

MQAPsingle: A quasi single-model approach for estimation of the quality of individual protein structure models


Iskierko Z, Sharma PS, Prochowicz D, Fronc K, D'Souza F, Toczydłowska D, Stefaniak F, Noworyta K

Molecularly Imprinted Polymer (MIP) Film with Improved Surface Area Developed by Using Metal-Organic Framework (MOF) for Sensitive Lipocalin (NGAL) Determination.

ACS Appl Mater Interfaces.

Glow D, Kurkowska M, Czarnecka J, Szczepaniak K, Pianka D, Kappert V, Bujnicki JM, Skowronek KJ

Identification of protein structural elements responsible for the diversity of sequence preferences among Mini-III RNases.

Sci Rep.

Kalisiak K, Kuliński TM, Tomecki R, Cysewski D, Pietras Z, Chlebowski A, Kowalska K, Dziembowski A

A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans

Nucleic Acids Res

Krzyminska-Siemaszko R, Chudek J, Suwalska A, Lewandowicz M, Mossakowska M, Kroll-Balcerzak R, Wizner B, Tobis S, Mehr K, Wieczorowska-Tobis K

Health status correlates of malnutrition in the polish elderly population - Results of the Polsenior Study

Eur Rev Med Pharmacol Sci

Budzinska M, Owczarz M, Pawlik-Pachucka E, Roszkowska-Gancarz M , Slusarczyk P, Puzianowska-Kuznicka M

miR-96, miR-145 and miR-9 expression increases, and IGF-1R and FOXO1 expression decreases in peripheral blood mononuclear cells of aging humans

BMC Geriatr

NCD Risk Factor Collaboration (793 Collaborators within M. Mossakowska and P. Ślusarczyk)

A century of trends in adult human height


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Grulich M, Brezovský J, Štěpánek V, Palyzová A, Marešová H, Zahradník J, Kyslíková E, Kyslík P

In-silico driven engineering of enantioselectivity of a penicillin G acylase towards active pharmaceutical ingredients

J Mol Catal B-Enzym

Tudek B, Zdżalik-Bielecka D, Tudek A, Kosicki K, Fabisiewicz A, Speina E

Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes

Free Radic Biol Med

Bochtler M, Kolano A, Xu G-L

DNA demethylation pathways: Additional players and regulators


Jasińska M, Miłek J, Cymerman IA, Łęski S, Kaczmarek L, Dziembowska M

miR-132 Regulates Dendritic Spine Structure by Direct Targeting of Matrix Metalloproteinase 9 mRNA

Mol Neurobiol.

Szychowska M, Siwek W, Pawolski D, Kazrani AA, Pyrc K, Bochtler M

Type III CRISPR complexes from Thermus thermophilus

Acta Biochim Pol

Wasilewski M, Chojnacka K, Chacinska A

Protein trafficking at the crossroads to mitochondria

Biochim Biophys Acta

Wasilewski M, Chojnacka K, Chacinska A

Białka mitochondrialne – import, eksport, degradacja

Postępy Biochemii

Stracy M, Jaciuk M, Uphoff S, Kapanidis AN, Nowotny M, Sherratt DJ, Zawadzki P

Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli

Nat Commun.

Piotrowicz K, Pac A, Skalska AB, Chudek J, Klich-Rączka A, Szybalska A, Michel JP, Grodzicki T

Clustering of geriatric deficits emerges to be an essential feature of ageing - results of a cross-sectional study in Poland

Aging (Albany NY)

Korzeniowski P, Wiweger M.

Pseudoloma neurophilia (Microsporidia) – poważne zagrożenie dla hodowli laboratoryjnej danio pręgowanego (Danio rerio, Hamilton 1822)

Życie Weterynaryjne

Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J

Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches


Gruszczynska-Biegala J, Sladowska M, Kuznicki J

AMPA Receptors Are Involved in Store-Operated Calcium Entry and Interact with STIM Proteins in Rat Primary Cortical Neurons

Frontiers in Cellular Neuroscience

Nadrowski P, Chudek J, Skrzypek M, Puzianowska-Kuźnicka M, Mossakowska M, Więcek A, Zdrojewski T, Grodzicki T, Kozakiewicz K

Associations between cardiovascular disease risk factors and IL-6 and hsCRP levels in the elderly

Exp Gerontol

Callegari S, Richter F, Chojnacka K, Jans DC, Lorenzi I, Pacheu-Grau D, Jakobs S, Lenz C, Urlaub H, Dudek J, Chacinska A, Rehling P

TIM29 is a subunit of the human carrier translocase required for protein transport


Mikula M, Skrzypczak M, Goryca K, Paczkowska K, Ledwon JK, Statkiewicz M, Kulecka M, Grzelak M, Dabrowska M, Kuklinska U, Karczmarski J, Rumienczyk I, Jastrzebski K, Miaczynska M, Ginalski K, Bomsztyk K, Ostrowski J.

Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.

Nucleic Acids Res

Wegierski T, Gazda K, Kuznicki J

Microscopic analysis of Orai-mediated store-operated calcium entry in cells with experimentally altered levels of amyloid precursor protein

Biochem Biophys Res Commun

Van Laer B, Roovers M, Wauters L, Kasprzak JM, Dyzma M, Deyaert E, Singh R, Feller A, Bujnicki JM, Droogmans L, Versées W

Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue

Nucleic Acids Res

Dawson WK, Bujnicki JM

Computational modeling of RNA 3D structures and interactions

Curr Opin Struct Biol

Boniecki MJ, Lach G, Dawson WK, Tomala K, Lukasz P, Soltysinski T, Rother KM, Bujnicki JM

SimRNA: a coarse-grained method for RNA folding simulations and 3D structure prediction

Nucleic Acids Res

Ukleja M, Cuellar J, Siwaszek A, Kasprzak JM, Czarnocki-Cieciura M, Bujnicki JM, Dziembowski A, Valpuesta J

The architecture of the Schizosaccharomyces pombe CCR4-NOT complex

Nature Commun

Matelska D, Kurkowska M, Purta E, Bujnicki JM, Dunin-Horkawicz S

Loss of conserved non-coding RNAs in genomes of bacterial endosymbionts

Genome Biol Evol

Yahara K, Furuta Y, Morimoto S, Kikutake C, Komukai S, Matelska D, Dunin-Horkawicz S, Bujnicki JM, Uchiyama I, Kobayashi I

Genome-wide survey of codons under diversifying selection in a highly recombining bacterial species, Helicobacter pylori


Magnus MM, Boniecki MJ, Dawson WK, Bujnicki JM

SimRNAweb: a web server for RNA 3D structure modeling with optional restraints

Nucleic Acids Res.

Bochtler M., Piasecka A

Haloferax volcanii UbaA, catalytic engine for sampylation and sulfur transfer


Skałecka A, Liszewska E, Bilinski R, Gkogkas C, Khoutorsky A, Malik AR, Sonenberg N, Jaworski J

mTOR kinase is needed for the development and stabilization of dendritic arbors in newly born olfactory bulb neurons

Dev Neurobiol

Cendrowski J, Mamińska A, Miaczynska M

Endocytic regulation of cytokine receptor signaling

Cytokine Growth Factor Rev

van Scheppingen J, Iyer AM, Prabowo AS, Mühlebner A, Anink JJ, Scholl T, Feucht M, Jansen FE, Spliet WG, Krsek P, Zamecnik J, Buccoliero AM, Giordano F, Genitori L, Kotulska K, Jozwiak S, Jaworski J, Liszewska E, van Vliet EA, Aronica E

Expression of microRNAs miR21, miR146a, and miR155 in tuberous sclerosis complex cortical tubers and their regulation in human astrocytes and SEGA-derived cell cultures


Jagielska E, Chojnacka O, Sabala I

LytM Fusion with SH3b-Like Domain Expands Its Activity to Physiological Conditions

Microb Drug Resist

Turakhiya U, von der Malsburg K, Gold VA, Guiard B, Chacinska A, van der Laan M, Ieva R

Protein Import by the Mitochondrial Presequence Translocase in the Absence of a Membrane Potential

J Mol Biol

Di Cesare M, … Mossakowska M, … Slusarczyk P, … - 756 collaborators (NCD-RisC)

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants


Zhou B, … Mossakowska M, … Slusarczyk P, … - 513 collaborators (NCD-RisC)

Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants


Prajsner A, Chudek J, Szybalska A, Piotrowicz K, Zejda J, Więcek A

Socioeconomic determinants of prostate-specific antigen testing and estimation of the prevalence of undiagnosed prostate cancer in an elderly Polish population based on the PolSenior study

Arch Med Sci

Kozak-Szkopek E, Broczek K, Slusarczyk P, Wieczorowska-Tobis K, Klich-Raczka A, Szybalska A, Mossakowska M

Prevalence of chronic pain in the elderly Polish population – results of the PolSenior study

Arch Med Sci

Wrobel L, Sokol AM, Chojnacka M, Chacinska A

The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly

Sci Rep

Puzianowska-Kuznicka M, Owczarz M, Wieczorowska-Tobis K, Nadrowski P, Chudek J, Slusarczyk P, Skalska A, Jonas M, Franek E, Mossakowska M

Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study

Immunity & Ageing

Mierzejewska K, Bochtler M, Czapinska H

On the role of steric clashes in methylation control of restriction endonuclease activity

Nucleic Acids Res

Haniewicz P, Floris D, Farci D, Kirkpatrick J, Loi MC, Büchel C, Bochtler M, Piano D

Isolation of Plant Photosystem II Complexes by Fractional Solubilization

Front Plant Sci

Topf U, Wrobel L, Chacinska A

Chatty Mitochondria: Keeping Balance in Cellular Protein Homeostasis

Trends Cell Biol

Hamann L, Bustami J, Iakoubov L, Szwed M, Mossakowska M, Schumann RR, Puzianowska-Kuznicka M

TLR-6 SNP P249S is associated with healthy aging in nonsmoking Eastern European Caucasians - A cohort study

Immun Ageing

Kevenaar JT, Bianchi S, van Spronsen M, Olieric N, Lipka J,Frias CP, Mikhaylova M, Harterink M, Keijzer N, Wulf PS, Hilbert M, Kapitein LC, de Graaff E, Ahkmanova A, Steinmetz MO, Hoogenraad CC

Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity

Curr Biol

Song J, Mu Y, Li C, Bergh A, Miaczynska M, Heldin CH, Landström M

APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain


Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M

ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors

Sci Signal

Tan H, Onichtchouk D, Winata C

DANIO-CODE: Toward an Encyclopedia of DNA Elements in Zebrafish


Nowotny M, Gaur V

Structure and mechanism of nucleases regulated by SLX4

Curr Opin Struct Biol

Zajac-Gawlak I, Pospiech D, Kroemeke A, Mossakowska M, Gába A, Pelclová J, Pridalová M, Kłapcinska B

Physical activity, body composition and general health status of physically active students of the University of the Third Age (U3A)

Archives of Gerontology and Geriatrics

Lipka J, Kapitein LC, Jaworski J, Hoogenraad CC

Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites


Wasiak I, Kulikowska A, Janczewska M, Michalak M, Cymerman IA, Nagalski A, Kallinger P, Szymanski WW, Ciach T

Dextran Nanoparticle Synthesis and Properties

PLoS One

Zdrojewski T, Wizner B, Więcek A, Ślusarczyk P, Chudek J, Mossakowska M, Bandosz P, Bobak M, Kozakiewicz K, Broda G, Wyrzykowski B, Grodzicki T

Prevalence, awareness, and control of hypertension in elderly and very elderly in Poland: results of a cross-sectional representative survey

J Hypertens

Szymanska E, Skowronek A, Miaczynska M

Impaired dynamin 2 function leads to increased AP-1 transcriptional activity through the JNK/c-Jun pathway

Cell Signal

Nagalski A, Puelles L, Dabrowski M, Wegierski T, Kuznicki J, Wisniewska MB

Molecular anatomy of the thalamic complex and the underlying transcription factors

Brain Struct Funct


Machnicka AM, Kaminska KH, Dunin-Horkawicz S, Bujnicki JM.

Phylogenomics and sequence-structure-function relationships in the GmrSD family of Type IV restriction enzymes.

BMC Bioinformatics

Kulcenty K, Wróblewska J, Mazurek S, Liszewska E, Jaworski J.

Molecular mechanisms of induced pluripotency.

Contemp Oncol (Pozn)

Jorstad A, Nigro B, Cali C, Wawrzyniak M, Fua P, Knott G.

NeuroMorph: A Toolset for the Morphometric Analysis and Visualization of 3D Models Derived from Electron Microscopy Image Stacks.


Vassetzky Y, Gout I, Kuznicki J.

Research reforms: Ukrainian science needs elixir of youth.


The RNAcentral Consortium (Petrov AI et al within Bujnicki JM)

RNAcentral: a comprehensive database of non-coding RNA sequences

Nucleic Acids Res

Bocian-Ostrzycka KM, Łasica AM, Dunin-Horkawicz S, Grzeszczuk MJ, Drabik K, Dobosz AM, Godlewska R, Nowak E, Collet J-F, Jagusztyn-Krynicka EK

Functional and evolutionary analyses of Helicobacter pylori HP0231 (DsbK) protein with strong oxidative and chaperone activity characterized by a highly diverged dimerization domain

Frontiers in Microbiology

Kalaidzidis I, Miaczynska M, Brewińska-Olchowik M, Hupalowska A, Ferguson C, Parton RG, Kalaidzidis Y, Zerial M

APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments

J Cell Biol

Zheng H, Shabalin I, Handing K, Bujnicki JM, Minor M

Magnesium binding architectures in RNA crystal structures: validation binding preferences, classification, and motif detection

Nucleic Acids Res

Tuszynska I, Magnus M, Jonak K, Dawson W, Bujnicki JM

NPDock – a web server for protein-nucleic acid docking

Nucleic Acids Res

Plotka M, Kaczorowska AK, Morzywolek A, Makowska J, Kozlowski LP, Thorisdottir A, Skírnisdottir S, Hjörleifsdottir S, Fridjonsson OH, Hreggvidsson GO, Kristjansson JK, Dabrowski S, Bujnicki JM, Kaczorowski T

Biochemical Characterization and Validation of a Catalytic Site of a Highly Thermostable Ts2631 Endolysin from the Thermus scotoductus Phage vB_Tsc2631

PLoS One

Philips A, Lach G, Bujnicki JM

Computational methods for prediction of RNA interactions with metal ions and small organic ligands

Methods Enzymol

Miao Z, Adamiak RW, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cheng C, Chojnowski G, Chou FC, Cordero P, Cruz JA, Ferré-D'amaré AR, Das R, Ding F, Dokholyan NV, Dunin-Horkawicz S, Kladwang W, Krokhotin A, Lach G, Magnus M, Major F, Mann TH, Masquida B, Matelska D, Meyer M, Peselis A, Popenda M, Purzycka KJ, Serganov A, Stasiewicz J, Szachniuk M, Tandon A, Tian S, Wang J, Xiao Y, Xu X, Zhang J, Zhao P, Zok T, Westhof E

RNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures


Liu S, Mozaffari-Jovin S, Wollenhaupt J, Santos KF, Theuser M, Dunin-Horkawicz S, Fabrizio P, Bujnicki JM, Lührmann R, Wahl MC

A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing


Glow D, Pianka D, Sulej A, Kozlowski L, Czarnecka J, Chojnowski G, Skowronek KJ, Bujnicki JM

Sequence-specific cleavage of dsRNA by Mini-III RNase

Nucleic Acids Res

Deo S, Patel TR, Chojnowski G, Koul A, Dzananovic E, McEleney K, Bujnicki JM, McKenna SA

Characterization of the termini of the West Nile virus genome and their interactions with the small isoform of the 2' 5'-Oligoadenylate Synthetase family

J Struct Biol

Czerwoniec A, Kasprzak JM, Bytner P, Dobrychlop M, Bujnicki JM

Structure and intrinsic disorder of the proteins of the Trypanosoma brucei editosome


Chojnowski G, Walen T, Piatkowski P, Potrzebowski W, Bujnicki JM

Brickworx builds recurrent RNA and DNA structural motifs into medium and low-resolution electron density maps

Acta Crystallogr D Biol Crystallogr

Chawla M, Oliva R, Bujnicki JM, Cavallo L

An atlas of RNA base pairs involving modified nucleobases with optimal geometries and accurate energies

Nucleic Acids Res

Boekema C, Owens F, Love A, Li Z, Sakkaris P, Dawson WK

A magnetic origin of cuprate superconductivity? A MaxEnt-mu SR view

Int J Mod Phys B

Blatter M, Dunin-Horkawicz S, Grishina I, Maris C, Thore S, Maier T, Bindereif A, Bujnicki JM, Allain FHT

The signature of the five-stranded vRRM fold defined by functional, structural and computational analysis of the hnRNP L protein

J Mol Biol

Bocian-Ostrzycka KM, Łasica AM, Dunin-Horkawicz S, Grzeszczuk MJ, Drabik K, Dobosz AM, Godlewska R, Nowak E, Collet J-F, Jagusztyn-Krynicka EK

Functional and evolutionary analyses of Helicobacter pylori HP0231 (DsbK) protein with strong oxidative and chaperone activity characterized by a highly diverged dimerization domain

Frontiers in Microbiology

Grabowska M, Jagielska E, Czapinska H, Bochtler M, Sabala I

High resolution structure of an M23 peptidase with a substrate analogue

Sci Rep

Burmistrz M, Dudek B, Staniec D, Rodriguez Martinez JI, Bochtler M, Potempa J, Pyrc K

Functional Analysis of Porphyromonas gingivalis W83 CRISPR-Cas Systems

J Bacteriol

Keatinge M, Bui H, Menke A, Chen YC, Sokol AM, Bai Q, Ellett F, Da Costa M, Burke D, Gegg M, Trollope L, Payne T, McTighe A, Mortiboys H, de Jager S, Nuthall H, Kuo MS, Fleming A, Schapira AH, Renshaw SA, Highley JR, Chacinska A, Panula P, Burton EA, O'Neill MJ, Bandmann O

Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death

Hum Mol Genet

Trosiuk TV, Shalak VF, Szczepanowski RH , Negrutskii BS, El'skaya AV

Non-catalytic N-terminal domain negatively influences the nucleotide exchange activity of translation elongation factor 1Bα


Zhao H, Ghirlando R, Alfonso C, Arisaka F, Attali I, Bain DL, Bakhtina MM, Becker DF, Bedwell GJ, Bekdemir A, Besong TM, Birck C, Brautigam CA, Brennerman W, Byron O, Bzowska A, Chaires JB, Chaton CT, Cölfen H, Connaghan KD, Crowley KA, Curth U, Daviter T, Dean WL, Díez AI, Ebel C, Eckert DM, Eisele LE, Eisenstein E, England P, Escalante C, Fagan JA, ... Szczepanowski RH,.. Schuck P

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation

PLoS One

Esteves da Silva M, Adrian M, Schätzle P, Lipka J, Watanabe T, Cho S, Futai K, Wierenga CJ, Kapitein LC, Hoogenraad CC

Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture

Cell Rep

Sakowska P, Jans DC, Mohanraj K, Riedel D, Jakobs S, Chacinska A

The oxidation status of Mic19 regulates MICOS assembly

Mol Cell Biol

Malik AR, Liszewska E, Skalecka A, Urbanska M, Iyer AM, Swiech LJ, Perycz M, Parobczak K, Pietruszka P, Zarebska MM, Macias M, Kotulska K, Borkowska J, Grajkowska W, Tyburczy ME, Jozwiak S, Kwiatkowski DJ, Aronica E, Jaworski J

Tuberous sclerosis complex neuropathology requires glutamate-cysteine ligase

Acta Neuropathol Commun

Malik AR, Liszewska E, Jaworski J

Matricellular proteins of the Cyr61/CTGF/NOV (CCN) family and the nervous system

Front Cell Neurosci

Cymerman IA, Gozdz A, Urbanska M, Milek J, Dziembowska M, Jaworski J

Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3βMistargeted mitochondrial proteins activate a proteostatic response in the cytosol

PLoS One

Banach-Orlowska M, Szymanska E, Miaczynska M

APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription


Torun A, Szymańska E, Castanon I, Wolińska-Nizioł L, Bartosik A, Jastrzębski K, Miętkowska M, González-Gaitán M, Miaczynska M

Endocytic adaptor protein Tollip inhibits canonical Wnt signaling

PLoS One

Wrobel L, Topf U, Bragoszewski P , Wiese S, Sztolsztener ME , Oeljeklaus S, Varabyova A, Lirski M, Chroscicki P, Mroczek S, Januszewicz E, Dziembowski A, Koblowska M, Warscheid B, Chacinska A

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol


Karolczak J, Sobczak M, Skowronek K, Rędowicz MJ

A Kinase Anchoring Protein 9 Is a Novel Myosin VI Binding Partner That Links Myosin VI with the PKA Pathway in Myogenic Cells

Biomed Res Int.

Roszczenko P, Grzeszczuk M, Kobierecka P, Wywial E, Urbanowicz P, Wincek P, Nowak E, Jagusztyn-Krynicka EK

Helicobacter pylori HP0377, a member of the Dsb family, is an untypical multifunctional CcmG that cooperates with dimeric thioldisulfide oxidase HP0231

BMC Microbiol.

Kocełak P, Olszanecka-Glinianowicz M, Owczarek AJ, Krupa W, Obirek P, Bożentowicz-Wikarek M, Brzozowska A, Mossakowska M, Zdrojewski T, Skalska A, Więcek A, Chudek J

Plasma visfatin/nicotinamide phosphoribosyltransferase (visfatin/NAMPT) concentration in elderly subjects with metabolic syndrome

Pol Arch Med Wewn

Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K, Rominger A

Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment

Mol Psychiatry.

Bragoszewski P, Wasilewski M, Sakowska P, Gornicka A, Böttinger L, Qiu J, Wiedemann N, Chacinska A

Retro-translocation of mitochondrial intermembrane space proteins

Proc Natl Acad Sci U S A

Chojnacka M, Gornicka A, Oeljeklaus S, Warscheid B, Chacinska A

Cox17 is an auxiliary factor involved in the control of the mitochondrial contact site and cristae organizing system

J Biol Chem

Barchiesi A, Wasilewski M, Chacinska A, Tell G, Vascotto C

Mitochondrial translocation of APE1 relies on the MIA pathway

Nucleic Acids Res

Krzymińska-Siemaszko R, Mossakowska M, Skalska A, Klich-Rączka A, Tobis S, Szybalska A, Cylkowska-Nowak M, Olszanecka-Glinianowicz M, Chudek J, Wieczorowska-Tobis K.

Social and Economic Correlates of Malnutrition in Polish Elderly Population: The Results of PolSenior Study

J Nutr Health Aging

Holecki M, Jerzy C, Owczarek A, Olszanecka-Glinianowicz M, Bożentowicz-Wikarek M, Duława J, Mossakowska M, Zdrojewski T, Skalska A, Więcek A

Inflammation but not obesity or insulin resistance is associated with increased plasma fibroblast growth factor 23 concentration in the elderly

Clin Endocrinol (Oxf).

Laczmanski L, Lwow F, Mossakowska M, Puzianowska-Kuznicka M, Szwed M, Kolackov K, Krzyzanowska-Swiniarska B, Bar-Andziak E, Chudek J, Sloka N, Milewicz A

Association between vitamin D concentration and levels of sex hormones in an elderly Polish population with different genotypes of VDR polymorphisms (rs10735810, rs1544410, rs7975232, rs731236)


Bożentowicz-Wikarek M, Kocełak P, Owczarek A, Olszanecka-Glinianowicz M, Mossakowska M, Skalska A, Więcek A, Chudek J

Plasma fibroblast growth factor 23 concentration and iron status. Does the relationship exist in the elderly population?

Clin Biochem

Kocelak P, Olszanecka-Glinianowicz M, Owczarek A, Bożentowicz-Wikarek M, Brzozowska A, Mossakowska M, Zdrojewski T, Grodzicki T, Więcek A, Chudek J

Plasma visfatin/nicotinamide phosphoribosyltransferase levels in hypertensive elderly - results from the PolSenior substudy

J Am Soc Hypertens

Gaur V, Wyatt HDM, Komorowska W, Szczepanowski RH, de Sanctis D, Gorecka KM, West SC, Nowotny M

Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease

Cell Reports

Sochacka E, Szczepanowski RH, Cypryk M, Sobczak M, Janicka M, Kraszewska K, Bartos P, Chwialkowska A, Nawrot B

2-Thiouracil deprived of thiocarbonyl function preferentially base pairs with guanine rather than adenine in RNA and DNA duplexes

Nucleic Acids Res

Topolska-Woś AM, Shell SM, Kilańczyk E, Szczepanowski RH, Chazin WJ, Filipek A

Dimerization and phosphatase activity of calcyclin-binding protein/Siah-1 interacting protein: the influence of oxidative stress


Winata CL, Kondrychyn I, Korzh V

Changing Faces of Transcriptional Regulation Reflected by Zic3

Current Genomics

Majewski L, Kuznicki J

SOCE in neurons: Signaling or just refilling?

BBA-Mol Cell Res

Bednarska-Makaruk M, Rodo M, Szirkowiec W, Mossakowska M, Puzianowska-Kuźnicka M, Skalska A, Zdrojewski T, Ryglewicz D, Wehr H

Paraoxonase 1 activity and level of antibodies directed against oxidized low density lipoproteins in a group of an elderly population in Poland - PolSenior study.

Arch Gerontol Geriatr.

Prajsner A, Chudek J, Szybalska A, Piotrowicz K, Zejda J, Więcek A, PolSenior Study Group

Socioeconomic profile of elderly Polish men treated for benign prostate hyperplasia: Results of the population-based PolSenior study

European Geriatric Medicine

Iakoubov L, Mossakowska M, Szwed M, Puzianowska-Kuznicka M

A Common Copy Number Variation Polymorphism in the CNTNAP2 Gene: Sexual Dimorphism in Association with Healthy Aging and Disease


Kolanczyk M, Krawitz P, Hecht J, Hupalowska A, Miaczynska M, Marschner K, Schlack C, Emerich D, Kobus K, Kornak U, Robinson PN, Plecko B, Grangl G, Uhrig S, Mundlos S, Horn D

Missense variant in CCDC22 causes X-linked recessive intellectual disability with features of Ritscher-Schinzel/3C syndrome

Eur J Hum Genet

Roszkowska-Gancarz M, Jonas M, Owczarz M , Kurylowicz A, Polosak J, Franek E, Slusarczyk P, Mossakowska M, Puzianowska-Kuznicka M

Age-related changes of leptin and leptin receptor variants in healthy elderly and long-lived adults

Geriatr Gerontol Int

Grabowska M, Jagielska E, Czapinska H, Bochtler M, Sabala I

High resolution structure of an M23 peptidase with a substrate analogue

Sci Rep


Figiel M, Nowotny M.

Crystal structure of RNase H3-substrate complex reveals parallel evolution of RNA/DNA hybrid recognition.

Nucleic Acids Res.

Mathys H, Basquin J, Ozgur S, Czarnocki-Cieciura M, Bonneau F, Aartse A, Dziembowski A, Nowotny M, Conti E, Filipowicz W.

Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression.

Mol Cell.

Machnicka M, Olchowik A, Grosjean H, Bujnicki JM.

Distribution and frequencies of post-transcriptional modifications in tRNAs.

RNA Biol.

Byszewska M, Smietanski M, Purta E, Bujnicki JM.

RNA methyltransferases involved in 5' cap biosynthesis.

RNA Biol.

Gallagher JM, Yamak A, Kirilenko P, Black S, Bochtler M, Lefebvre C, Nemer M, Latinkić BV

Carboxy terminus of GATA4 transcription factor is required for its cardiogenic activity and interaction with CDK4

Mech Dev

Skubiszewska A, Wodzyńska K, Szybalska A, Ślusarczyk P, Broczek K, Puzianowska-Kuźnicka M, Olędzka G, Mossakowska M

Ocena sprawności funkcjonalnej warszawskich stulatków w zakresie podstawowych czynności życia codziennego – wyniki wstępne

Gerontologia Polska

Kocelak P, Olszanecka-Glinianowicz M, Owczarek A, Bozentowicz-Wikarek M, Brzozowska A, Mossakowska M, Skalska A, Wiecek A, Chudek J

Plasma visfatin/nicotinamide phosphoribosyltransferase (visfatin/NAMPT) concentration is not related to kidney function in elderly subjects

Clin Chem Lab Med.

Bovellan M, Romeo Y, Biro M, Boden A, Chugh P, Yonis A, Vaghela M, Fritzsche M, Moulding D, Thorogate R, Jégou A, Thrasher AJ, Romet-Lemonne G, Roux PP, Paluch EK, Charras G

Cellular control of cortical actin nucleation

Curr Biol

Ieva R, Schrempp SG, Opaliński L Wollweber F, Höß P, Heißwolf AK, Gebert M, Zhang Y, Guiard B, Rospert S, Becker T, Chacinska A, Pfanner N, van der Laan M

Mgr2 functions as lateral gatekeeper for preprotein sorting in the mitochondrial inner membrane

Mol Cell.

Honarnejad K, Daschner A, Gehring AP, Szybinska A, Giese A, Kuznicki J, Bracher F, Herms J

Identification of tetrahydrocarbazoles as novel multifactorial drug candidates for treatment of Alzheimer's disease

Transl Psychiatry.

Szczepaniak K, Lach G, Bujnicki JM, Dunin-Horkawicz S

Designability landscape reveals sequence features that define axial helix rotation in four-helical homo-oligomeric antiparallel coiled-coil structures

J Struct Biol.

Grabowska AD, Wywiał E, Dunin-Horkawicz S , Lasica AM, Wösten MM, Nagy-Staroń A, Godlewska R, Bocian-Ostrzycka K, Pieńkowska K, Laniewski P, Bujnicki JM, van Putten JP, Jagusztyn-Krynicka EK

Functional and bioinformatics analysis of two Campylobacter jejuni homologs of the thiol-disulfide oxidoreductase, DsbA

PLoS One.

Walen T, Chojnowski G, Gierski P,Bujnicki JM,

ClaRNA: a classifier of contacts in RNA 3D structures based on a comparative analysis of various classification schemes

Nucleic Acids Res.

Ramos-Molina B, Lambertos A, Lopez-Contreras AJ, Kasprzak JM, Czerwoniec A, Bujnicki JM, Cremades A, Penafiel R

Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2

FEBS Open Bio.

Sierocka I, Kozlowski LP, Bujnicki JM, Jarmolowski A, Szweykowska-Kulinska Z

Female-specific gene expression in dioecious liverwort Pellia endiviifolia is developmentally regulated and connected to archegonia production

BMC Plant Biol.

Magnus M, Matelska D, Lach G, Chojnowski G, Boniecki MJ, Purta E, Dawson W, Dunin-Horkawicz S, Bujnicki JM

Computational modeling of RNA 3D structures, with the aid of experimental restraints

RNA Biol.

Rother K, Rother M, Skiba P, Bujnicki JM

Automated modeling of RNA 3D structure

Methods Mol Biol

Miętus M, Nowak E, Jaciuk M, Kustosz P, Studnicka J, Nowotny M

Crystal structure of the catalytic core of Rad2: insights into the mechanism of substrate binding

Nucleic Acids Res

Gornicka A, Bragoszewski P, Chroscicki P, Wenz LS, Schulz C, Rehling P, Chacinska A

A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria

Mol Biol Cell

Kurkowiak M, Ziętkiewicz E, Witt M

Recent advances in primary ciliary dyskinesia genetics

J Med Genet

Melin J, Schulz C, Wrobel L, Bernhard O, Chacinska A, Jahn O, Schmidt B, Rehling P

Presequence recognition by the tom40 channel contributes to precursor translocation into the mitochondrial matrix

Mol Cell Biol

Sokol AM, Sztolsztener ME, Wasilewski M, Heinz E, Chacinska A

Mitochondrial protein translocases for survival and wellbeing


Skalska A, Wizner B, Więcek A, Zdrojewski T, Chudek J, Klich-Rączka A, Piotrowicz K, Błędowski P, Mossakowska M, Michel JP, Grodzicki T

Reduced functionality in everyday activities of patients with self-reported heart failure hospitalization - Population-based study results

Int J Cardiol

Olszanecka-Glinianowicz M, Owczarek A, Bożentowicz-Wikarek M, Brzozowska A, Mossakowska M, Zdrojewski T, Grodzicki T, Więcek A, Chudek J

Relationship between circulating visfatin/NAMPT, nutritional status and insulin resistance in an elderly population - results from the PolSenior substudy


Sabala I, Jagielska E, Bardelang PT, Czapinska H, Dahms SO, Sharpe JA, James R, Than ME, Thomas NR, Bochtler M

Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans


Mierzejewska K, Siwek W, Czapinska H, Kaus-Drobek M, Radlinska M, Skowronek K, Bujnicki JM, Dadlez M, Bochtler M

Structural basis of the methylation specificity of R.DpnI

Nucleic Acids Res.

Wojciechowski M, Rafalski D, Kucharski R, Misztal K, Maleszka J, Bochtler M, Maleszka R

Insights into DNA hydroxymethylation in the honeybee from in-depth analyses of TET dioxygenase

Open Biol

Mills F, Bartlett TE, Dissing-Olesen L, Wisniewska MB, Kuznicki J, Macvicar BA, Wang YT, Bamji SX

Cognitive flexibility and long-term depression (LTD) are impaired following β-catenin stabilization in vivo

Proc Natl Acad Sci U S A.

Klich-Rączka A, Piotrowicz K, Mossakowska M, Skalska A, Wizner B, Broczek K, Wieczorowska-Tobis K, Grodzicki T

The assessment of cognitive impairment suspected of dementia in Polish elderly people: results of the population-based PolSenior Study

Exp Gerontol

Laczmanski L, Milewicz A, Puzianowska-Kuznicka M, Lwow F, Kolackov K, Mieszczanowicz U, Pawlak M, Krzyzanowska-Swiniarska B, Bar-Andziak E, Chudek J, Mossakowska M

Interrelation between genotypes of the vitamin D receptor gene and serum sex hormone concentrations in the Polish elderly population: the PolSenior study

Exp Gerontol

Labuz-Roszak B, Skrzypek M, Pierzchała K, Machowska-Majchrzak A, Mossakowska M, Chudek J, Mańka-Gaca I, Bartman W, Więcek A

Secondary prevention of stroke in elderly people in Poland-Results of PolSenior study

Neurol Neurochir Pol

Chudek J, Kocełak P, Owczarek A, Bozentowicz-Wikarek M, Mossakowska M, Olszanecka-Glinianowicz M, Wiecek A

Fibroblast growth factor 23 (FGF23) and early chronic kidney disease in the elderly

Nephrol Dial Transplant

Roszkowska-Gancarz M, Kurylowicz A, Polosak J, Mossakowska M, Franek E, Puzianowska-Kuźnicka M

Functional polymorphisms of the leptin and leptin receptor genes are associated with longevity and with the risk of myocardial infarction and of type 2 diabetes mellitus

Endokrynol Pol

Majorek KA, Dunin-Horkawicz S, Steczkiewicz K, Muszewska A, Nowotny M, Ginalski K, Bujnicki JM

The RNase H-like superfamily: new members, comparative structural analysis and evolutionary classification

Nucleic Acids Res.

Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J

Uniform nomenclature for the mitochondrial contact site and cristae organizing system

J Cell Biol.

Toczyłowska-Mamińska R, Olszewska A, Laskowski M, Bednarczyk P, Skowronek K, Szewczyk A

Potassium channel in the mitochondria of human keratinocytes

J Invest Dermatol

Sadowski Ł, Jastrzębski K, Purta E, Hellberg C, Miaczynska M

Labeling of platelet-derived growth factor by reversible biotinylation to visualize its endocytosis by microscopy

Methods Enzymol.

Tomecki R, Drazkowska K, Kucinski I, Stodus K, Szczesny RJ, Gruchota J, Owczarek EP, Kalisiak K, Dziembowski A

Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target

Nucleic Acids Res.

Crochemore M, Iliopoulos CS, Kubica M, Radoszewski J, Rytter W, Stencel K, Walen T

New simple efficient algorithms computing powers and runs in strings

Discrete Applied Mathematics

Kazrani AA, Kowalska M, Czapinska H, Bochtler M

Crystal structure of the 5hmC specific endonuclease PvuRts1I

Nucleic Acids Res.

Ziętkiewicz E, Rutkiewicz E, Pogorzelski A, Klimek B, Voelkel K, Witt M

CFTR Mutations Spectrum and the Efficiency of Molecular Diagnostics in Polish Cystic Fibrosis Patients

PLoS One

Nowak E, Miller JT, Bona MK, Studnicka J, Szczepanowski RH, Jurkowski J, Le Grice SFJ, Nowotny M

Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry

Nature Structural & Molecular Biology

Tarnowski K, Fituch K, Szczepanowski RH, Dadlez M, Kaus-Drobek M

Patterns of structural dynamics in RACK1 protein retained throughout evolution: A hydrogen-deuterium exchange study of three orthologs

Protein Sci

Geiger JC, Lipka J, Segura I, Hoyer S, Schlager MA, Wulf PS, Weinges S, Demmers J, Hoogenraad CC, Acker-Palmer A

The GRIP1/14-3-3 Pathway Coordinates Cargo Trafficking and Dendrite Development

Dev Cell

Mossakowska M , Broczek K, Wieczorowska-Tobis K, Klich-Raczka A, Jonas M, Pawlik-Pachucka E, Safranow K, Kuznicki J , Puzianowska-Kuznicka M

Cognitive Performance and Functional Status Are the Major Factors Predicting Survival of Centenarians in Poland

J Gerontol A Biol Sci Med Sci

Geremek M, Ziętkiewicz E, Bruinenberg M, Franke L, Pogorzelski A, Wijmenga C, Witt M

Ciliary genes are down-regulated in bronchial tissue of primary ciliary dyskinesia patients

PLoS One

Smietanski M, Werner M, Purta E, Kaminska KH, Stepinski J, Darzynkiewicz E, Nowotny M, Bujnicki JM

Structural analysis of human 2′-O-ribose methyltransferases involved in mRNA cap structure formation

Nat Commun

Chojnowski G, Walen T, Bujnicki JM

RNA Bricks - a database of RNA 3D motifs and their interactions

Nucleic Acids Res.

Dzananovic E, Patel TR, Chojnowski G, Boniecki MJ, Deo S, McEleney K, Harding SE, Bujnicki JM, McKenna SA

Solution conformation of Adenovirus Virus Associated RNA-I and its interaction with PKR

J Struct Biol

Plotka M, Kaczorowska AK, Stefanska A, Morzywolek A, Fridjonsson OH, Dunin-Horkawicz S, Kozlowski L, Hreggvidsson GO, Kristjansson JK, Dabrowski S, Bujnicki JM, Kaczorowski T

Novel Highly Thermostable Endolysin from Thermus scotoductus MAT2119 Bacteriophage Ph2119 with Amino Acid Sequence Similarity to Eukaryotic Peptidoglycan Recognition Proteins

Appl Environ Microbiol

Tuszynska I, Matelska D, Magnus M, Chojnowski G, Kasprzak JM, Kozlowski LP, Dunin-Horkawicz S, Bujnicki JM

Computational modeling of protein-RNA complex structures


Jaremko M, Jaremko L, Nowakowski M, Wojciechowski M, Szczepanowski RH, Panecka R, Zhukov I, Bochtler M, Ejchart A

NMR structural studies of the first catalytic half-domain of ubiquitin activating enzyme

J Struct Biol

Skupien A, Konopka A, Trzaskoma P, Labus J, Gorlewicz A, Swiech L, Babraj M, Dolezyczek H, Figiel I, Ponimaskin E, Wlodarczyk J, Jaworski J, Wilczynski GM, Dzwonek J

CD44 regulates dendrite morphogenesis through Src tyrosine kinase-dependent positioning of the Golgi

J Cell Sci


Madej D, Borowska K, Bylinowska J, Szybalska A, Pietruszka B

Dietary intakes of iron and zinc assessed in a selected group of the elderly: are they adequate

Rocz Panstw Zakl Hig

Jaworski J

Perceptible shape of memories

Biologia w szkole

Liszewska E, Jaworski J

Why do we need induced pluripotent stem cells in neurobiology?

Postepy Biochem

Wegierski T

Mikroskopowe metody rejestracji wewnątrzkomórkowych odpowiedzi wapniowych


Paluch EK, Raz E

The role and regulation of blebs in cell migration

Curr Opin Cell Biol

Xu C, Liu R, Mehta AK, Guerrero-Ferreira RC, Wright ER, Dunin-Horkawicz S, Morris K, Serpell LC, Zuo X, Wall JS, Conticello VP

Rational design of helical nanotubes from self-assembly of coiled-coil lock washers

J Am Chem Soc.

Górecka KM, Komorowska W, Nowotny M

Crystal structure of RuvC resolvase in complex with Holliday junction substrate

Nucleic Acids Res

Biro M, Romeo Y, Kroschwald S, Bovellan M, Boden A, Tcherkezian J, Roux PP, Charras G, Paluch EK

Cell cortex composition and homeostasis resolved by integrating proteomics and quantitative imaging

Cytoskeleton (Hoboken)

Haniewicz P, De Sanctis D, Büchel C, Schröder WP, Loi MC, Kieselbach T, Bochtler M, Piano D

Isolation of monomeric photosystem II that retains the subunit PsbS

Photosynth Res

Philips A, Milanowska K, Lach G, Bujnicki JM

LigandRNA: computational predictor of RNA-ligand interactions


Czeredys M, Samluk L, Michalec K, Tułodziecka K, Skowronek K, Nałęcz KA

Caveolin-1 - a novel interacting partner of organic cation/carnitine transporter (octn2): effect of protein kinase C on this interaction in rat astrocytes.

PLoS One

Gutmajster E, Witecka J, Wyskida M, Koscinska-Marczewska J, Szwed M, Owczarz M, Mossakowska M, Milewicz A, Puzianowska-Kuznicka M, Zejda J, Wiecek A, Chudek J, Sieron A.L

Telomere Length in Elderly Caucasians Weakly Correlates with Blood Cell Counts

The Scientific World Journal

Honarnejad K, Daschner A, Giese A, Zall A, Schmidt B, Szybinska A, Kuznicki J, Herms J

Development and Implementation of a High-Throughput Compound Screening Assay for Targeting Disrupted ER Calcium Homeostasis in Alzheimer's Disease

PLoS One

Czeredys M, Gruszczynska-Biegala J, Schacht T, Methner A, Kuznicki J

Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington’s disease

Front. Mol. Neurosci

Lipka J, Kuijpers M,Jaworski J, Hoogenraad CC

Mutations in cytoplasmic dynein and its regulators cause malformations of cortical development and neurodegenerative diseases

Biochem Soc Trans

Honarnejad K, Kirsch AK, Daschner A, Szybinska A, Kuznicki J, Herms J

FRET-Based Calcium Imaging: A Tool for High-Throughput/Content Phenotypic Drug Screening in Alzheimer Disease

J Biomol Screen

Janusz A, Milek J, Perycz M, Pacini L, Bagni C, Kaczmarek L, Dziembowska M

The fragile x mental retardation protein regulates matrix metalloproteinase 9 mRNA at synapses

J Neurosci

Iakoubov L, Mossakowska M, Szwed M, Duan Z, Sesti F, Puzianowska-Kuznicka M

A Common Copy Number Variation (CNV) Polymorphism in the CNTNAP4 Gene: Association with Aging in Females

PLoS One

Miaczynska M

Effects of membrane trafficking on signaling by receptor tyrosine kinases

Cold Spring Harb Perspect Biol.

Gruszczynska-Biegala J, Kuznicki J

Native STIM2 and ORAI1 proteins form a calcium-sensitive and thapsigargin-insensitive complex in cortical neurons

J Neurochem

Bedzhov I, Alotaibi H, Basilicata MF, Ahlborn K,Liszewska E, Brabletz T, Stemmler MP

Adhesion, but not a specific cadherin code, is indispensable for ES cell and induced pluripotency

Stem Cell Res

Matelska D, Purta E, Panek S, Boniecki MJ, Bujnicki JM, Dunin-Horkawicz S

S6:S18 ribosomal protein complex interacts with a structural motif present in its own mRNA


Dudzik J, Chang WC, Kannan AM, Filipek S, Viswanathan S, Li P, Renugopalakrishnan V, Audette GF

Cross-linked glucose oxidase clusters for biofuel cell anode catalysts


Clark AG, Dierkes K, Paluch EK

Monitoring actin cortex thickness in live cells

Biophys J

Wu Y, Yuan S, Chen S, Wu D, Chen J, Wu J

Enhancing the production of galacto-oligosaccharides by mutagenesis of Sulfolobus solfataricus β-galactosidase

Food Chem

Kubica M, Kulczyńskia T, Radoszewskia J, Rytter W,Walen T

A linear time algorithm for consecutive permutation pattern matching

Information Processing Letters

Bednarczyk P, Wieckowski MR, Broszkiewicz M, Skowronek K, Siemen D, Szewczyk A

Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain

PLoS One

Pulawski W, Filipek S, Zwolinska A, Debinski A, Krzysko K, Garduño-Juárez R, Viswanathan S, Renugopalakrishnan V

Low-temperature molecular dynamics simulations of horse heart cytochrome c and comparison with inelastic neutron scattering data

Eur Biophys J

Chon H, Sparks JL, Rychlik M, Nowotny M, Burgers PM, Crouch RJ, Cerritelli SM

RNase H2 roles in genome integrity revealed by unlinking its activities

Nucleic Acids Res

Crochemore M, Iliopoulos C.S, Kociumaka T, Kubica M, Pachocki J, Radoszewski J, Rytter W,Tyczyński W, Waleń T

A note on efficient computation of all Abelian periods in a string

Information Processing Letters

Latek D, Pasznik P, Carlomagno T, Filipek S

Towards Improved Quality of GPCR Models by Usage of Multiple Templates and Profile-Profile Comparison

PLoS One

Wojda U, Kuznicki J

Alzheimer's disease modeling: ups, downs, and perspectives for human induced pluripotent stem cells

J Alzheimers Dis

Maître JL, Berthoumieux H, Gabriel Krens SF, Salbreux G, Jülicher F, Paluch E, Heisenberg CP

Cell adhesion mechanics of zebrafish gastrulation


Qiu J, Wenz LS, Zerbes RM, Oeljeklaus S, Bohnert M, Stroud DA, Wirth C, Ellenrieder L, Thornton N, Kutik S, Wiese S, Schulze-Specking A, Zufall N, Chacinska A, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N, Wiedemann N, Becker T

Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation


Varabyova A, Topf U, Kwiatkowska P, Wrobel L, Kaus-Drobek M, Chacinska A

Mia40 and MINOS act in parallel with Ccs1 in the biogenesis of mitochondrial Sod1


Pawlowski M, Bogdanowicz A, Bujnicki JM

QA-RecombineIt: a server for quality assessment and recombination of protein models

Nucleic Acids Res

Lukasiak P, Antczak M, Ratajczak T, Bujnicki JM, Szachniuk M, Adamiak RW, Popenda M, Blazewicz J

RNAlyzer--novel approach for quality analysis of RNA structural models

Nucleic Acids Res

Bujnicki JM, Tiuryn J

Bioinformatics and computational biology in Poland

PLoS Comput Biol

Puton T, Kozlowski LP, Rother KM, Bujnicki JM

CompaRNA: a server for continuous benchmarking of automated methods for RNA secondary structure prediction

Nucleic Acids Res.

Nadrowski P, Chudek J, Grodzicki T, Mossakowska M, Skrzypek M, Wiecek A, Zdrojewski T, Kozakiewicz K

Plasma level of N-terminal pro brain natriuretic peptide (NT-proBNP) in elderly population in Poland - the PolSenior Study

Exp Gerontol.

Golanska E, Sieruta M, Corder E, Gresner SM, Pfeffer A, Chodakowska-Zebrowska M, Sobow TM, Klich I, Mossakowska M, Szybinska A, Barcikowska M, Liberski PP

The prion protein M129V polymorphism: Longevity and cognitive impairment among Polish centenarians


Macias M, Blazejczyk M, Kazmierska P, Caban B, Skalecka A, Tarkowski B, Rodo A, Konopacki J, Jaworski J

Spatiotemporal Characterization of mTOR Kinase Activity Following Kainic Acid Induced Status Epilepticus and Analysis of Rat Brain Response to Chronic Rapamycin Treatment

PLoS One

Kapitein LC, van Bergeijk P, Lipka J, Keijzer N, Wulf PS, Katrukha EA, Akhmanova A, Hoogenraad CC

Myosin-V Opposes Microtubule-Based Cargo Transport and Drives Directional Motility on Cortical Actin

Curr Biol

Sadowski L, Jastrzębski K, Kalaidzidis Y, Heldin CH, Hellberg C, Miaczynska M

Dynamin Inhibitors Impair Endocytosis and Mitogenic Signaling of PDGF


Bragoszewski P, Gornicka A, Sztolsztener ME, Chacinska A

The ubiquitin-proteasome system regulates mitochondrial intermembrane space proteins

Mol Cell Biol

Kuzniewska B, Rejmak E, Malik AR, Jaworski J, Kaczmarek L, Kalita K

Brain-derived neurotrophic factor induces matrix metalloproteinase-9 expression in neurons via serum response factor/c-Fos pathway

Mol Cell Biol

van Spronsen M, Mikhaylova M, Lipka J, Schlager MA, van den Heuvel DJ, Kuijpers M, Wulf PS, Keijzer N, Demmers J, Kapitein LC, Jaarsma D, Gerritsen HC, Akhmanova A, Hoogenraad CC

TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites


Jaworska A, Dzbek J, Styczynska M, Kuznicki J

Analysis of calcium homeostasis in fresh lymphocytes from patients with sporadic Alzheimer's disease or mild cognitive impairment

Biochim Biophys Acta

Bik W, Baranowska-Bik A, Wolinska-Witort E, Kalisz M, Broczek K, Mossakowska M, Baranowska B

Assessment of adiponectin and its isoforms in Polish centenarians

Exp Gerontol

Golanska E, Sieruta M, Gresner SM, Pfeffer A, Chodakowska-Zebrowska M, Sobow TM, Klich I, Mossakowska M, Szybinska A, Barcikowska M, Liberski PP

APBB2 genetic polymorphisms are associated with severe cognitive impairment in centenarians

Exp Gerontol

Wisniewska MB

Physiological Role of β-Catenin/TCF Signaling in Neurons of the Adult Brain

Neurochem Res

Nowak E, Potrzebowski W, Konarev PV, Rausch JW, Bona MK, Svergun DI, Bujnicki JM, Le Grice SF, Nowotny M

Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid

Nucleic Acids Res

Malik AR, Urbanska M, Gozdz A, Swiech LJ, Nagalski A, Perycz M, Blazejczyk M, Jaworski J

CYR61, a matricellular protein, is needed for dendritic arborization of hippocampal neurons

J Biol Chem

Wrobel L, Trojanowska A, Sztolsztener ME, Chacinska A

Mitochondrial protein import: Mia40 facilitates Tim22 translocation into the inner membrane of mitochondria

Mol Biol Cell

Varabyova A, Stojanovski D, Chacinska A

Mitochondrial protein homeostasis


Kapustian LL, Vigontina OA, Rozhko OT, Ryabenko DV, Michowski W, Lesniak W, Filipek A, Kroupskaya IV, Sidorik LL

Hsp90 and its co-chaperone, Sgt1, as autoantigens in dilated cardiomyopathy

Heart Vessels

Roszkowska-Gancarz M, Bartoszewicz Z, Polosak J, Kurylowicz A, Jonas M, Mossakowska M, Franek E, Puzianowska-Kuźnicka M

Total and high molecular weight adiponectin and level-modifying polymorphisms of ADIPOQ in centenarians

Endokrynologia Polska

Malik AR, Urbanska M, Macias M, Skalecka A, Jaworski J

Beyond control of protein translation: What we have learned about the non-canonical regulation and function of mammalian target of rapamycin (mTOR)

Biochim Biophys Acta

Esteras N, Alquézar C, Bermejo-Pareja F, Bialopiotrowicz E, Wojda U, Martín-Requero A

Downregulation of extracellular signal-regulated kinase 1/2 activity by calmodulin KII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer's disease patients

Neurobiol Aging

Milanowska K, Mikolajczak K, Lukasik A, Skorupski M, Balcer Z, Machnicka MA, Nowacka M, Rother KM, Bujnicki JM

RNApathwaysDB – a database of RNA maturation and decay pathways

Nucleic Acids Res

Machnicka MA, Milanowska K, Osman Oglou O, Purta E, Kurkowska M, Olchowik A, Januszewski W, Kalinowski S, Dunin-Horkawicz S, Rother KM, Helm M, Bujnicki JM, Grosjean H

MODOMICS: a database of RNA modification pathways: 2013 update

Nucleic Acids Res

Nagalski A, Irimia M, Szewczyk L, Ferran JL, Misztal K, Kuznicki J, Wisniewska MB

Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain

Brain Struct Funct

Wojciechowski M, Czapinska H, Bochtler M

CpG Underrepresentation and the Bacterial CpG Specific DNA Methyltransferase M.MpeI

Proc Natl Acad Sci U S A.

Sztolsztener ME, Brewinska A, Guiard B, Chacinska A

Disulfide bond formation: sulfhydryl oxidase ALR controls mitochondrial biogenesis of human MIA40


Pyrzynska B, Banach-Orlowska M, Teperek-Tkacz M, Miekus K, Drabik G, Majka M, Miaczynska M

Multifunctional protein APPL2 contributes to survival of human glioma cells

Mol Oncol.

Kraszewska MD, Dawidowska M, Kosmalska M, Sędek Ł, Grzeszczak W, Kowalczyk JR, Szczepański T, Witt M

BCL11B, FLT3, NOTCH1 and FBXW7 mutation status in T-cell Acute Lymphoblastic Leukemia patients

Blood Cells, Molecules and Diseases

Żylicz M.

Biologia syntetyczna: jak powstawało życie na Ziemi?



Pfeffer A, Chodakowska M, Czyżewski K, Gabryelewicz T, Łuczywek Ł, Mossakowska M, Broczek K, Barcikowska M

The Prevalence of Dementia in Warsaw Centenarians: a Population – Based Study

Postępy Nauk Medycznych

Kozlowski L, Orlowski J, Bujnicki JM

Structure prediction of alternatively spliced proteins In „Alternative pre-mRNA Splicing: Theory and Protocols: The Complete Guide for Biomedical Scientists”

Rother K, Rother M, Boniecki M, Puton T, Tomala K, Lukasz P, Bujnicki JM

Template-based and template-free modeling of RNA 3D structure: inspirations from protein structure modeling In "RNA Structure Prediction and Modelling"

Pulawski W, Ghoshdastider U, Andrisano V, Filipek S

Ubiquitous amyloids

Appl Biochem Biotechnol

Kozlowski LP, Bujnicki JM

MetaDisorder: A meta-server for the prediction of intrinsic disorder in proteins

BMC Bioinformatics

Kasprzak JM, Czerwoniec A, Bujnicki JM

Molecular evolution of dihydrouridine synthases

BMC Bioinformatics

Korneta I, Bujnicki JM

Intrinsic disorder in the human spliceosomal proteome

PLoS Comput Biol

Kusio-Kobialka M, Wolanin K, Podszywalow-Bartnicka P, Sikora E, Skowronek K, McKenna SL, Ghizzoni M, Dekker FJ, Piwocka K

Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage


Roszczenko P, Radomska KA, Wywial E, Collet JF, Jagusztyn-Krynicka EK

A novel insight into the oxidoreductase activity of Helicobacter pylori HP0231 protein

PLoS One

Al-Haggar M, Madej-Pilarczyk A, Kozlowski L, Bujnicki JM, Yahia S, Abdel-Hadi D, Shams A, Ahmad N, Hamed S, Puzianowska-Kuznicka M

A novel homozygous p.Arg527Leu LMNA mutation in two unrelated egyptian families causes overlapping mandibuloacral dysplasia and progeria syndrome

Eur J Hum Genet

Naldi M, Fiori J, Pistolozzi M, Drake AF, Bertucci C, Wu R, Mlynarczyk K, Filipek S, De Simone A, Andrisano V

Amyloid β-Peptide 25-35 Self-Assembly and Its Inhibition: A Model Undecapeptide System to Gain Atomistic and Secondary Structure Details of the Alzheimer's Disease Process and Treatment

ACS Chem Neurosci

Yuan S, Ghoshdastider U, Trzaskowski B, Latek D, Debinski A, Pulawski W, Wu R, Gerke V, Filipek S

The Role of Water in Activation Mechanism of Human N-Formyl Peptide Receptor 1 (FPR1) Based on Molecular Dynamics Simulations

PLoS One

Magnus M, Pawlowski M, Bujnicki JM

MetaLocGramN: A meta-predictor of protein subcellular localization for Gram-negative bacteria

Biochim Biophys Acta

Laczmanski L, Milewicz A, Lwow F, Puzianowska-Kuznicka M, Pawlak M, Kolackov K, Jedrzejuk D, Krzyzanowska-Swiniarska B, Bar-Andziak E, Chudek J, Mossakowska M

Vitamin D receptor gene polymorphism and cardiovascular risk variables in elderly Polish subjects

Gynecol Endocrinol

Skalska A, Wizner B, Piotrowicz K, Klich-Rączka A, Klimek E, Mossakowska M, Rowiński R, Kozak-Szkopek E, Jóźwiak A, Gąsowski J, Grodzicki T

The prevalence of falls and their relation to visual and hearing impairments among a nation-wide cohort of older Poles

Exp Gerontol

Skowronek K, Boniecki MJ, Kluge B, Bujnicki JM

Rational engineering of sequence specificity in R.MwoI restriction endonuclease

Nucleic Acids Res

Poleszak K, Kaminska KH, Dunin-Horkawicz S, Lupas A, Skowronek KJ, Bujnicki JM

Delineation of structural domains and identification of functionally important residues in DNA repair enzyme Exonuclease VII

Nucleic Acids Res

Korneta I, Magnus M, Bujnicki JM

Structural bioinformatics of the human spliceosomal proteome

Nucleic Acids Res

Drozdz M, Piekarowicz A, Bujnicki JM, Radlinska M

Novel non-specific DNA adenine methyltransferases

Nucleic Acids Res

Sulej AA, Tuszynska I, Skowronek KJ, Nowotny M, Bujnicki JM

Sequence-specific cleavage of the RNA strand in DNA-RNA hybrids by the fusion of ribonuclease H with a zinc finger

Nucleic Acids Res

Pawlowski M, Bujnicki JM

The utility of comparative models and the local model quality for protein crystal structure determination by Molecular Replacement

BMC Bioinformatics

Pietal MJ, Szostak N, Rother KM, Bujnicki JM

RNAmap2D -- calculation, visualization and analysis of contact and distance maps for RNA and protein-RNA complex structures

BMC Bioinformatics

Bochtler M

Structural basis of the TAL effector-DNA interaction

Biol Chem

Wiech M, Olszewski MB, Tracz-Gaszewska Z, Wawrzynow B, Zylicz M, Zylicz A

Molecular Mechanism of Mutant p53 Stabilization: The Role of HSP70 and MDM2

PLoS One

Wisniewska MB, Nagalski A, Dabrowski M, Misztal K, Kuznicki J

Novel beta-catenin target genes identified in thalamic neurons encode modulators of neuronal excitability

BMC Genomics

Sabala I, Jonsson IM, Tarkowski A, Bochtler M

Anti-staphylococcal activities of lysostaphin and LytM catalytic domain

BMC Microbiol

Siwek W, Czapinska H, Bochtler M, Bujnicki JM, Skowronek K

Crystal structure and mechanism of action of the N6-methyladenine dependent type IIM restriction endonuclease

Nucleic Acids Res

Bukowy-Bieryłło Z, Ziętkiewicz E, Loges NT, Wittmer M, Geremek M, Olbrich H, Fliegauf M, Voelkel K, Rutkiewicz E, Rutland J, Morgan L, Pogorzelski A, Martin J, Haan E, Berger W, Omran H, Witt M

RPGR mutations might cause reduced orientation of respiratory cilia

Pediatr Pulmonol.

Winiarska M, Nowis D, Bil J, Glodkowska-Mrowka E, Muchowicz A, Wanczyk M, Bojarczuk K, Dwojak M, Firczuk M, Wilczek E, Wachowska M, Roszczenko K, Miaczynska M, Chlebowska J, Basak GW, Golab J

Prenyltransferases Regulate CD20 Protein Levels and Influence Anti-CD20 Monoclonal Antibody-mediated Activation of Complement-dependent Cytotoxicity

J Biol Chem

Böttinger L*, Gornicka A*, Czerwik T, Bragoszewski P, Loniewska-Lwowska A, Schulze-Specking A, Truscott KN, Guiard B, Milenkovic D, Chacinska A, *equally contributing first author

In vivo evidence for cooperation of Mia40 and Erv1 in the oxidation of mitochondrial proteins

Mol Biol Cell

Voegtle FN, Burkhart JM, Rao S, Gerbeth C, Hinrichs J, Martinou JC, Chacinska A, Sickmann A, Zahedi RP, Meisinger C

Intermembrane space proteome of yeast mitochondria

Mol Cell Proteomics

Bohnert M, Wenz LS, Zerbes RM, Horvath SE, Stroud DA, von der Malsburg K, Müller JM, Oeljeklaus S, Perschil I, Warscheid B, Chacinska A, Veenhuis M, van der Klei IJ, Daum G, Wiedemann N, Becker T, Pfanner N, van der Laan M

Role of MINOS in protein biogenesis of the mitochondrial outer membrane

Mol Biol Cell.

Knapska E, Macias M, Mikosz M, Nowak A, Owczarek D, Wawrzyniak M, Pieprzyk M, Cymerman IA, Werka T, Sheng M, Maren S, Jaworski J, Kaczmarek L

Functional anatomy of neural circuits regulating fear and extinction

Proc. Natl. Acad. Sci.

Green RA,Paluch E, Oegema K

Cytokinesis in Animal Cells

Annu Rev Cell Dev Biol.

Salbreux G, Charras G, Paluch E

Actin cortex mechanics and cellular morphogenesis

Trends Cell Biol.

Maître JL, Berthoumieux H, Krens SF, Salbreux G, Jülicher F, Paluch E, Heisenberg CP

Adhesion Functions in Cell Sorting by Mechanically Coupling the Cortices of Adhering Cells


Bergert M, Chandradoss SD, Desai RA, Paluch E

Cell mechanics control rapid transitions between blebs and lamellipodia during migration

Proc Natl Acad Sci U S A

Zerrouqi A, Pyrzynska B, Febbraio M, Brat DJ, Van Meir EG

P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3

J Clin Invest.

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Sosnowski TR, Koliński M, Gradoń L

Alteration of surface properties of dipalmitoyl phosphatidylcholine by benzo[a]pyrene: a model of pulmonary effects of diesel exhaust inhalation

J Biomed Nanotechnol

Samluk L, Czeredys M, Skowronek K, Nałęcz KA

Protein kinase C regulates amino acid transporter ATB

Biochem Biophys Res Commun.

Malenda A, Skrobanska A, Issat T, Winiarska M, Bil J, Oleszczak B, Sinski M, Firczuk M, Bujnicki JM, Chlebowska J, Staruch AD, Glodkowska-Mrowka E, Kunikowska J, Krolicki L, Szablewski L, Gaciong Z, Koziak K, Jakobisiak M, Golab J, Nowis DA

Statins Impair Glucose Uptake in Tumor Cells


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Lammens W, Le Roy K, Yuan S, Vergauwen R, Rabijns A, Van Laere A, Strelkov SV, Van den Ende W

Crystal structure of 6-SST/6-SFT from Pachysandra terminalis, a plant fructan biosynthesizing enzyme in complex with its acceptor substrate 6-kestose

Plant J.

Lach G, DeKievet M, Jentschura UD

Einstein–Hopf drag, Doppler shift of thermal radiation and blackbody drag: Three perspectives on quantum friction

Cent. Eur. J. Phys.

Goudarzi M, Banisch TU, Mobin MB, Maghelli N, Tarbashevich K, Strate I, van den Berg J, Blaser H, Bandemer S, Paluch E, Bakkers J, Tolić-Nørrelykke IM, Raz E

Identification and Regulation of a Molecular Module for Bleb-Based Cell Motility

Dev Cell

Fislage M, Roovers M, Tuszynska I, Bujnicki JM, Droogmans L, Versées W

Crystal structures of the tRNA:m(2)G6 methyltransferase Trm14/TrmN from two domains of life

Nucleic Acids Res

Cruz JA, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cao S, Das R, Ding F, Dokholyan NV, Flores SC, Huang L, Lavender CA, Lisi V, Major F, Mikolajczak K, Patel DJ, Philips A, Puton T, Santalucia J, Sijenyi F, Hermann T, Rother K, Rother M, Serganov A, Skorupski M, Soltysinski T, Sripakdeevong P, Tuszynska I, Weeks KM, Waldsich C, Wildauer M, Leontis NB, Westhof E

RNA-Puzzles: A CASP-like evaluation of RNA three-dimensional structure prediction


Chojnowski G, Bujnicki JM, Bochtler M

RIBER/DIBER: a software suite for crystal content analysis in the studies of protein-nucleic acid complexes


Bialopiotrowicz E, Szybinska A, Kuzniewska B, Buizza L, Uberti D, Kuznicki J, Wojda U

Highly Pathogenic Alzheimer's Disease Presenilin 1 P117R Mutation Causes a specific Increase in p53 and p21 Protein Levels and Cell Cycle Dysregulation in Human Lymphocytes

J Alzheimers Dis

Urbanska M, Gozdz A, Swiech LJ, Jaworski J

Mammalian target of rapamycin complex 1 (MTORC1) and 2 MTORC2) control the dendritic arbor morphology of hippocampal neurons


Hupalowska A, Pyrzynska B, Miaczynska M

APPL1 regulates basal NF-κB activity by stabilizing NIK

J Cell Sci

Stojanovski D, Bragoszewski P, Chacinska A

The MIA pathway: A tight bond between protein transport and oxidative folding in mitochondria


Zylicz-Stachula A, Zolnierkiewicz O, Lubys A, Ramanauskaite D, Mitkaite G, Bujnicki JM, Skowron P

Related bifunctional restriction endonuclease-methyltransferase triplets: TspDTI, Tth111II/TthHB27I and TsoI with distinct specificities

BMC Mol Biol

Roovers M, Oudjama Y, Fislage M, Bujnicki JM, Versées W, Droogmans L

The open reading frame TTC1157 of Thermus thermophilus HB27 encodes the methyltransferase forming N2-methylguanosine at position 6 in tRNA


Nakagome S, Mano S, Kozlowski L, Bujnicki JM, Shibata H, Fukumaki Y, Kidd JR, Kidd KK, Kawamura S, Oota H

Crohn's Disease Risk Alleles on the NOD2 Locus Have Been Maintained by Natural Selection on Standing Variation

Mol Biol Evol

Puton T, Kozlowski L, Tuszynska I, Rother K, Bujnicki JM

Computational methods for prediction of protein-RNA interactions

J Struct Biol

Rother K, Potrzebowski W, Puton T, Rother M, Wywial E, Bujnicki JM

A toolbox for developing bioinformatics software

Brief Bioinform

Hupalowska A, Miaczynska M

The new faces of endocytosis in signaling


Kennaway CK, Taylor JE, Song CF, Potrzebowski W, Nicholson W, White JH, Swiderska A,Obarska-Kosinska A, Callow P, Cooper LP, Roberts GA, Artero JB,Bujnicki JM, Trinick J, Kneale GG, Dryden DT

Structure and operation of the DNA-translocating type I DNA restriction enzymes

Genes Dev

Philips A, Milanowska K, Lach G, Boniecki M, Rother K, Bujnicki JM

MetalionRNA: computational predictor of metal-binding sites in RNA structures


Tinevez JY, Salbreux G, Paluch E

The mechanics of the cellular division or how to split a sphere into two?

Med Sci (Paris)

Trzaskowski B, Latek D, Yuan S, Ghoshdastider U, Debinski A, Filipek S

Action of Molecular Switches in GPCRs - Theoretical and Experimental Studies

Curr Med Chem

Paluch E, El-Samad H

Modeling and simulation of cellular functions

Mol Biol Cell

Buizza L, Cenini G, Lanni C, Ferrari-Toninelli G, Prandelli C, Govoni S, Buoso E, Racchi M, Barcikowska M, Styczynska M, Szybinska A, Butterfield DA, Memo M, Uberti D

Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease

PLoS One

Ziętkiewicz E, Bukowy-Bieryłło Z, Voelkel K, Klimek B, Dmeńska H, Pogorzelski A, Sulikowska-Rowińska A, Rutkiewicz E, Witt M

Mutations in radial spoke head genes and ultrastructural cilia defects in East-European cohort of primary ciliary dyskinesia patients.

PLoS One

Urbanska M, Swiech L, Jaworski J

Developmental plasticity of the dendritic compartment: focus on the cytoskeleton

Adv Exp Med Biol

Kraszewska MD, Dawidowska M, Kosmalska M, Sędek L, Grzeszczak W, Szczepański T, Witt M

DNA methylation pattern is altered in childhood T-cell acute lymphoblastic leukemia patients as compared with normal thymic subsets: insights into CpG island methylator phenotype in T-ALL


Kraszewska MD, Dawidowska M, Szczepanski T, Witt M

T-cell acute lymphoblastic leukaemia: recent molecular biology findings

Br J Haematol

Kraszewska MD, Dawidowska M, Kosmalska M, Sędek L, Grzeszczak W, Szczepański T, Witt M

Immunoglobulin/T-cell receptor gene rearrangements in the diagnostic paradigm of pediatric T-cell acute lymphoblastic leukemia patients

Leukemia & Lymphoma

Ziętkiewicz E, Witt M, Daca P, Zebracka-Gala J, Goniewicz M, Jarząb B, Witt M

Current genetic methodologies in the identification of disaster victims and in forensic analysis

J Appl Genet.

Hokkanen S, Feldmann HM, Ding H, Jung CK, Bojarski L, Renner-Müller I, Schüller U, Kretzschmar H, Wolf E, Herms J

Lack of Pur-alpha alters postnatal brain development and causes megalencephaly

Hum Mol Genet.


Błędowski P, Mossakowska M, Szybalska A

Program badawczy PolSenior – cele i metoda

Zeszyty Naukowe Ochrony Zdrowia. Zdrowie Publiczne i Zarządzanie

Bielska E, Lucas X, Czerwoniec A, Kasprzak JM, Kaminska KH, Bujnicki JM

Virtual screening strategies in drug design - methods and applications


Audette GF, Lombardo S, Dudzik J, Arruda TM, Kolinski M, Filipek S, Mukerjee S, Kannan AM, Thavasi V, Ramakrishna S, Chin M, Somasundaran P, Viswanathan S, Keles RS, Renugopalakrishnan V

Modeling of ligand binding to G protein coupled receptors: cannabinoid CB(1), CB (2) and adrenergic β (2)AR.

Materials Today

Milczarski P, Bolibok-Brągoszewska H, Myśków B, Stojałowski S, Heller-Uszyńska K, Góralska M, Brągoszewski P, Uszyński G, Kilian A, Rakoczy-Trojanowska M

A high density consensus map of rye (Secale cereale L.) based on DArT markers

PLoS One

Sikorski K, Czerwoniec A, Bujnicki JM, Wesoly J, Bluyssen HAR

STAT1 as a novel therapeutical target in pro-atherogenic signal integration of IFNg, TLR4 and IL-6 in vascular disease

Cytokine Growth Factor Rev.

Rother M, Rother K, Puton T, Bujnicki JM

RNA tertiary structure prediction with ModeRNA

Brief Bioinform

Milanowska K, Rother K, Bujnicki JM

Databases and bioinformatics tools for the study of DNA repair

Mol Biol Int

Liu J, Ganapathy K, Wywial E, Bujnicki JM, Nwogwugwu CA, Nes WD

Effect of substrate features and mutagenesis of active site tyrosine residues on the reaction course catalysed by Trypanosoma brucei sterol C-24-methyltransferase

Biochem J

Czerwoniec A, Bujnicki JM

Identification and modeling of a phosphatase-like domain in a tRNA 2'-O-ribosyl phosphate transferase Rit1p

Cell Cycle

Bateman A, Agrawal S, Birney E, Bruford EA, Bujnicki JM, Cochrane G, Cole JR, Dinger ME, Enright AJ, Gardner PP, Gautheret D, Griffiths-Jones S, Harrow J, Herrero J, Holmes IH, Huang HD, Kelly KA, Kersey P, Kozomara A, Lowe TM, Marz M, Moxon S, Pruitt KD, Samuelsson T, Stadler PF, Vilella AJ, Vogel JH, Williams KP, Wright MW, Zwieb C

RNAcentral: A vision for an international database of RNA sequences


Steinbeck JA, Henke N, Opatz J, Gruszczynska-Biegala J, Schneider L, Theiss S, Hamacher N, Steinfarz B, Golz S, Brüstle O, Kuznicki J, Methner A

Store-operated calcium entry modulates neuronal network activity in a model of chronic epilepsy

Exp Neurol.

Schulz C, Lytovchenko O, Melin J, Chacinska A, Guiard B, Neumann P, Ficner R, Jahn O, Schmidt B, Rehling P

Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex

J Cell Biol.

von der Malsburg K, Müller JM, Bohnert M, Oeljeklaus S, Kwiatkowska P, Becker T, Loniewska-Lwowska A, Wiese S, Rao S, Milenkovic D, Hutu DP, Zerbes RM, Schulze-Specking A, Meyer HE, Martinou JC, Rospert S, Rehling P, Meisinger C, Veenhuis M et all

Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis

Dev Cell.

Antonczak AK, Simova Z, Yonemoto IT, Bochtler M, Piasecka A, Czapinska H, Brancale A, Tippmann EM

Importance of single molecular determinants in the fidelity of expanded genetic codes

Proc Natl Acad Sci U S A.

Figiel M, Chon H, Cerritelli SM, Cybulska M, Crouch RJ, Nowotny M

The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutières syndrome defects

J Biol Chem

Hageman J, van Waarde MA, Zylicz A, Walerych D, Kampinga HH

The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities

Biochem J

Rother M, Rother K, Puton T, Bujnicki JM

ModeRNA: a tool for comparative modeling of RNA 3D structure

Nucleic Acids Res

Braun S, Humphreys C, Fraser E, Brancale A, Bochtler M, Dale TC

Amyloid-associated nucleic acid hybridisation

PLoS One

Werner M, Purta E, Kaminska KH, Cymerman IA, Campbell DA, Mittra B, Zamudio JR, Sturm NR, Jaworski J, Bujnicki JM

2'-O-ribose methylation of cap2 in human: function and evolution in a horizontally mobile family

Nucleic Acids Res

Rosta E, Nowotny M, Yang W, Hummer G

Catalytic mechanism of RNA backbone cleavage by ribonuclease H from quantum mechanics/molecular mechanics simulations

J Am Chem Soc.

Bledowski P, Mossakowska M, Chudek J, Grodzicki T, Milewicz A, Szybalska A, Wieczorowska-Tobis K, Wiecek A, Bartoszek A, Dabrowski A, Zdrojewski T

Medical, psychological and socioeconomic aspects of aging in Poland Assumptions and objectives of the PolSenior project

Exp Gerontol

Rajska-Neumann A, Mossakowska M, Klich-Rączka A, Życzkowska J, Grześkowiak E, Shieh S, Wieczorowska-Tobis K

Drug consumption among Polish centenarians

Arch Gerontol Geriatr

Becker T, Wenz LS, Krüger V, Lehmann W, Müller JM, Goroncy L, Zufall N, Lithgow T, Guiard B, Chacinska A, Wagner R, Meisinger C, Pfanner N

The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins

J Cell Biol.

Tuszynska I, Bujnicki JM

DARS-RNP and QUASI-RNP: New statistical potentials for protein-RNA docking

BMC Bioinformatics

Sedzinski J, Biro M, Oswald A, Tinevez JY, Salbreux G, Paluch E

Polar actomyosin contractility destabilizes the position of the cytokinetic furrow


Urbanska A, Sadowski L, Kalaidzidis Y, Miaczynska M

Biochemical characterization of APPL endosomes: the role of annexin A2 in APPL membrane recruitment


Rother M, Milanowska K, Puton T, Jeleniewicz J, Rother K, Bujnicki JM

ModeRNA server: an online tool for modeling RNA 3D structures


Rother K, Rother M, Boniecki M, Puton T, Bujnicki JM

Rother K, Rother M, Boniecki M, Puton T, Bujnicki JM

J Mol Model.

Misztal K, Wisniewska MB, Ambrozkiewicz M, Nagalski A, Kuznicki J

WNT protein-independent constitutive nuclear localization of beta-catenin protein and its low degradation rate in thalamic neurons.

J Biol Chem.

Spears JL, Rubio MA, Gaston KW, Wywial E, Strikoudis A, Bujnicki JM, Papavasiliou FN, Alfonzo JD

A single zinc ion is sufficient for an active Trypanosoma brucei tRNA editing deaminase

J Biol Chem

Tesfazgi Mebrhatu M, Wywial E, Ghosh A, Michiels CW, Lindner AB, Taddei F, Bujnicki JM, Van Melderen L, Aertsen A

Evidence for an evolutionary antagonism between Mrr and Type III modification systems.

Nucleic Acids Res

Rother K, Rother M, Boniecki M, Puton T, Tomala K, Lukasz P, Bujnicki JM

Template-based and template-free modeling of RNA 3D structure: inspirations from protein structure modeling

RNA Structure Prediction and Modelling

Kozlowski L, Orlowski J, Bujnicki JM

Structure prediction of alternatively spliced proteins

RNA splicing: The complete guide

Bukowy Z, Ziętkiewicz E, Witt M

In vitro culturing of ciliary respiratory cells--a model for studies of genetic diseases

J Appl Genet

Geremek M, Bruinenberg M, Ziętkiewicz E, Pogorzelski A, Witt M, Wijmenga C

Gene expression studies in cells from primary ciliary dyskinesia patients identify 208 potential ciliary genes

Hum Genet

Kapitein LC, Yau KW, Gouveia SM, van der Zwan WA, Wulf PS, Keijzer N, Demmers J, Jaworski J, Akhmanova A, Hoogenraad CC

NMDA Receptor Activation Suppresses Microtubule Growth and Spine Entry

J Neurosci

Clark AG, Paluch E

Mechanics and regulation of cell shape during the cell cycle

Results Probl Cell Differ

Perycz M, Urbanska AS, Krawczyk PS, Parobczak K, Jaworski J

Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neurons

J Neurosci

Swiech L, Blazejczyk M, Urbanska M, Pietruszka P, Dortland BR, Malik AR, Wulf PS, Hoogenraad CC, Jaworski J

CLIP-170 and IQGAP1 cooperatively regulate dendrite morphology

J Neurosci

Azoulay-Alfaguter I, Yaffe Y, Licht-Murava A, Urbanska M, Jaworski J, Pietrokovski S, Hirschberg K, Eldar-Finkelman H

Distinct molecular regulation of glycogen synthase kinase-3alpha isozyme controlled by its N-terminal region: functional role in calcium/calpain signaling

J Biol Chem

Jaciuk M, Nowak E, Skowronek K, Tańska A, Nowotny M

Structure of UvrA nucleotide excision repair protein in complex with modified DNA.

Nat Struct Mol Biol

Pilecka I, Sadowski L, Kalaidzidis Y, Miaczynska M

Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment

Exp Cell Res

Latek D, Kolinski M, Ghoshdastider U, Debinski A, Bombolewski R, Plazinska A, Jozwiak K, Filipek S

Modeling of ligand binding to G protein coupled receptors: cannabinoid CB(1), CB (2) and adrenergic β (2)AR

J Mol Model

Koch R, Lipton AS, Filipek S, Renugopalakrishnan V

Arginine interactions with anatase TiO(2) (100) surface and the perturbation of (49)Ti NMR chemical shifts - a DFT investigation: relevance to Renu-Seeram bio solar cell

J Mol Model

Gruszczynska-Biegala J, Pomorski P, Wisniewska MB, Kuznicki J

Differential Roles for STIM1 and STIM2 in Store-Operated Calcium Entry in Rat Neurons

PLoS One

Sobczak A, Debowska K, Blazejczyk M, Kreutz MR, Kuznicki J, Wojda U

Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth

Biochim Biophys Acta

Bialopiotrowicz E, Kuzniewska B, Kachamakova-Trojanowska N, Barcikowska M, Kuznicki J, Wojda U

Cell cycle regulation distinguishes lymphocytes from sporadic and familial Alzheimer's disease patients

Neurobiol Aging

Firczuk M, Wojciechowski M, Czapinska H, Bochtler M

DNA intercalation without flipping in the specific ThaI-DNA complex

Nucleic Acids Res

Husain N, Obranic S, Koscinski L, Seetharaman J, Babic F, Bujnicki JM, Maravic-Vlahovicek G, Sivaraman J

Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit

Nucleic Acids Res

Abrahams JP, Apweiler R, Balling R, Bertero MG, Bujnicki JM, Chayen NE, Chène P, Corthals GL, Dyląg T, Förster F, Heck AJ, Henderson PJ, Herwig R, Jehenson P, Kokalj SJ, Laue E, Legrain P, Martens L, Migliorini C, Musacchio A, Podobnik M, Schertler GF, Sc

"4D Biology for health and disease" workshop report

N Biotechnol

Sokolowska M, Czapinska H, Bochtler M

Hpy188I-DNA pre- and post-cleavage complexes--snapshots of the GIY-YIG nuclease mediated catalysis

Nucleic Acids Res

Milanowska K, Krwawicz J, Papaj G, Kosinski J, Poleszak K, Lesiak J, Osinska E, Rother K, Bujnicki JM

REPAIRtoire-a database of DNA repair pathways

Nucleic Acids Res


Bhagat J, Tanoh F, Nzuobontane E, Laurent T, Orlowski J, Roos M, Wolstencroft K, Aleksejevs S, Stevens R, Pettifer S, Lopez R, Goble CA

BioCatalogue: a universal catalogue of web services for the life sciences

Nucleic Acids Res

Tkaczuk KL

Trm13p, the tRNA:Xm4 modification enzyme from Saccharomyces cerevisiae is a member of the Rossmann-fold MTase superfamily: prediction of structure and active site

J Mol Model.

Rother K, Hoffmann S, Bulik S, Hoppe A, Gasteiger J, Holzhütter HG

IGERS: inferring Gibbs energy changes of biochemical reactions from reaction similarities

Biophys J.

Zubrienė A, Gutkowska M, Matulienė J, Chaleckis R, Michailovienė V, Voroncova A, Venclovas C, Zylicz A, Zylicz M, Matulis D

Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms

Biophys Chem

Kvardova V, Hrstka R, Walerych D, Muller P, Matoulkova E, Hruskova V, Stelclova D, Sova P, Vojtesek B

The new platinum(IV) derivative LA-12 shows stronger inhibitory effect on Hsp90 function compared to cisplatin

Mol Cancer

Czarnecka AM, Krawczyk T, Plak K, Klemba A, Zdrozny M, Arnold RS, Kofler B, Golik P, Szybinska A, Lubinski J, Mossakowska M, Bartnik E, Petros JA

Mitochondrial genotype and breast cancer predisposition

Oncol Rep

Ziętkiewicz E, Nitka B, Voelkel K, Skrzypczak U, Bukowy Z, Rutkiewicz E, Humińska K, Przystałowska H, Pogorzelski A, Witt M

Population specificity of the DNAI1 gene mutation spectrum in primary ciliary dyskinesia (PCD)

Respir Res

Polosak J, Roszkowska-Gancarz M, Kurylowicz A, Owczarz M, Dobosz P, Mossakowska M, Szybinska A, Puzianowska-Kuznicka M

Decreased expression and the Lys751Gln polymorphism of the XPD gene are associated with extreme longevity


Adler G, Parczewski M, Czerska E, Loniewska B, Kaczmarczyk M, Gumprecht J, Grzeszczak W, Szybinska A, Mossakowska M, Ciechanowicz A

An age-related decrease in factor V Leiden frequency among Polish subjects

J Appl Genet

Klemba A, Kowalewska M, Kukwa W, Tonska K, Szybinska A, Mossakowska M, Scinska A, Golik P, Koper K, Radziszewski J, Kukwa A, Czarnecka AM, Bartnik E

Mitochondrial genotype in vulvar carcinoma - cuckoo in the nest

J Biomed Sci

Piechota M, Korostynski M, Solecki W, Gieryk A, Slezak M, Bilecki W, Ziolkowska B, Kostrzewa E, Cymerman I, Swiech L, Jaworski J, Przewlocki R

The dissection of transcriptional modules regulated by various drugs of abuse in the mouse striatum.

Genome Biol

Michowski W, Ferretti R, Wisniewska MB, Ambrozkiewicz M, Beresewicz M, Fusella F, Skibinska-Kijek A, Zablocka B, Brancaccio M, Tarone G, Kuznicki J.

Morgana/CHP-1 is a novel chaperone able to protect cells from stress.

Biochim Biophys Acta

Wisniewska MB, Misztal K, Michowski W, Szczot M, Purta E, Lesniak W, Klejman ME, Dabrowski M, Filipkowski RK, Nagalski A, Mozrzymas JW, Kuznicki J.

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain.

J Neurosci

Chojnowski G, Bochtler M

DIBER: protein, DNA or both?

Acta Crystallogr D Biol Crystallogr

Gentsch M, Kaczmarczyk A, van Leeuwen K, de Boer M, Kaus-Drobek M, Dagher MC, Kaiser P, Arkwright PD, Gahr M, Rösen-Wolff A, Bochtler M, Secord E, Britto-Williams P, Saifi GM, Maddalena A, Dbaibo G, Bustamante J, Casanova JL, Roos D, Roesler J

Alu-repeat-induced deletions within the NCF2 gene causing p67-phox-deficient chronic granulomatous disease (CGD)

Hum Mutat

Chojnowski G, Breer K, Narczyk M, Wielgus-Kutrowska B, Czapinska H, Hashimoto M, Hikishima S, Yokomatsu T, Bochtler M, Girstun A, Staroń K, Bzowska A

1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state

Biochem Biophys Res Commun

Diz-Muñoz A, Krieg M, Bergert M, Ibarlucea-Benitez I, Muller DJ, Paluch E, Heisenberg CP

Control of directed cell migration in vivo by membrane-to-cortex attachment.

PLoS Biol

Khan F, Furuta Y, Kawai M, Kaminska KH, Ishikawa K, Bujnicki JM, Kobayashi I

A putative mobile genetic element carrying a novel type IIF restriction-modification system (PluTI).

Nucleic Acids Res

Tuszynska I, Bujnicki JM

Predicting atomic details of the unfolding pathway for YibK, a knotted protein from the SPOUT superfamily

J Biomol Struct Dyn

Kaminska KH, Purta E, Hansen LH, Bujnicki JM, Vester B, Long KS

Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria.

Nucleic Acids Res

Zhou X, Chua TK, Tkaczuk KL, Bujnicki JM, Sivaraman J

The crystal structure of Escherichia coli spermidine synthase SpeE reveals a unique substrate-binding pocket.

J Struct Biol

Pukáncsik M, Békési A, Klement E, Hunyadi-Gulyás E, Medzihradszky KF, Kosinski J, Bujnicki JM, Alfonso C, Rivas G, Vértessy BG

Physiological truncation and domain organization of a novel uracil-DNA-degrading factor.


Zhang Z, Theler D, Kaminska KH, Hiller M, de la Grange P, Pudimat R, Rafalska I, Heinrich B, Bujnicki JM, Allain FH, Stamm S

The YTH domain is a novel RNA binding domain.

J Biol Chem

Pukszta S, Schilke B, Dutkiewicz R, Kominek J, Moczulska K, Stepien B, Reitenga KG, Bujnicki JM, Williams B, Craig EA, Marszalek J

Co-evolution-driven switch of J-protein specificity towards an Hsp70 partner.


Kempenaers M, Roovers M, Oudjama Y, Tkaczuk KL, Bujnicki JM, Droogmans L

New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA.

Nucleic Acids Res

Husain N, Tkaczuk KL, Tulsidas SR, Kaminska KH, Cubrilo S, Maravić-Vlahovicek G, Bujnicki JM, Sivaraman J

Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.

Nucleic Acids Res

Kosinski J, Hinrichsen I, Bujnicki JM, Friedhoff P, Plotz G

Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair.

Hum Mutat

Chua TK, Seetharaman J, Kasprzak JM, Ng C, Patel BK, Love C, Bujnicki JM, Sivaraman J

Crystal structure of a fructokinase homolog from Halothermothrix orenii

J Struct Biol

Gajda MJ, Tuszynska I, Kaczor M, Bakulina AY, Bujnicki JM

FILTREST3D: discrimination of structural models using restraints from experimental data.


Kieper J, Lauber C, Gimadutdinow O, Urbańska A, Cymerman I, Ghosh M, Szczesny B, Meiss G

Production and characterization of recombinant protein preparations of Endonuclease G-homologs from yeast, C. elegans and humans.

Protein Expr Purif

Stefaniuk M, Swiech L, Dzwonek J, Lukasiuk K

Expression of Ttyh1, a member of the Tweety family in neurons in vitro and in vivo and its potential role in brain pathology.

J Neurochem

Rychlik MP, Chon H, Cerritelli SM, Klimek P, Crouch RJ, Nowotny M

Crystal structures of RNase H2 in complex with nucleic acid reveal the mechanism of RNA-DNA junction recognition and cleavage.

Mol Cell

Miaczynska M, Bar-Sagi D

Signaling endosomes: seeing is believing

Curr Opin Cell Biol

Kolinski M, Filipek S

Study of a structurally similar kappa opioid receptor agonist and antagonist pair by molecular dynamics simulations.

J Mol Model

Nagalski A, Kiersztan A.

Physiology and molecular mechanism of glucocorticoid action.

Postepy Hig Med Dosw

Spooren A, Rondou P, Debowska K, Lintermans B, Vermeulen L, Samyn B, Skieterska K, Debyser G, Devreese B, Vanhoenacker P, Wojda U, Haegeman G, Van Craenenbroeck K.

Resistance of the dopamine D4 receptor to agonist-induced internalization and degradation.

Cell Signal

Uberti D, Cenini G, Bonini SA, Barcikowska M, Styczynska M, Szybinska A, Memo M.

Increased CD44 gene expression in lymphocytes derived from Alzheimer disease patients.

Neurodegener Dis

Bojarski L, Debowska K, Wojda U.

In vitro findings of alterations in intracellular calcium homeostasis in schizophrenia.

Prog Neuropsychopharmacol Biol Psychiatry

Piano D, El Alaoui S, Korza HJ, Filipek R, Sabala I, Haniewicz P, Buechel C, De Sanctis D, Bochtler M

Crystallization of the Photosystem II core complex and its chlorophyll binding subunit CP43 from transplastomic plants of Nicotiana tabacum

Photosynth Res

Kirkegaard T, Roth AG, Petersen NH, Mahalka AK, Olsen OD, Moilanen I, Zylicz A, Knudsen J, Sandhoff K, Arenz C, Kinnunen PK, Nylandsted J, Jäättelä M

Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.


Zurawska A, Urbanski J, Matuliene J, Baraniak J, Klejman MP, Filipek S, Matulis D, Bieganowski P

Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo.

Biochim Biophys Acta

Walerych D, Gutkowska M, Klejman MP, Wawrzynow B, Tracz Z, Wiech M, Zylicz M, Zylicz A

ATP binding to Hsp90 is sufficient for effective chaperoning of p53 protein.

J Biol Chem


Ohya T, Miaczynska M, Coskun U, Lommer B, Runge A, Drechsel D, Kalaidzidis Y, Zerial M

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.


Olchowik M, Miaczyńska M

[Effectors of GTPase Rab5 in endocytosis and signal transduction]

Postepy Biochem

Banach-Orlowska M, Pilecka I, Torun A, Pyrzynska B, Miaczynska M

Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex

Biochem J

Sadowski L, Pilecka I, Miaczynska M

Signaling from endosomes: location makes a difference.

Exp Cell Res

M. Kolinfski, S. Filipek

Studies of the Activation Steps Concurrent to Ligand Binding in δOR and κOR Opioid Receptors Based on Molecular Dynamics Simulations


Kilanczyk E, Filipek S, Jastrzebska B, Filipek A

CacyBP/SIP binds ERK1/2 and affects transcriptional activity of Elk-1

Biochem Biophys Res Commun

Austermann J, Nazmi AR, Heil A, Fritz G, Kolinski M, Filipek S, Gerke V

Generation and characterization of a novel, permanently active S100P mutant.

Biochim Biophys Acta

Thavasi V, Lazarova T, Filipek S, Kolinski M, Querol E, Kumar A, Ramakrishna S, Padrós E, Renugopalakrishnan V

Study on the feasibility of bacteriorhodopsin as bio-photosensitizer in excitonic solar cell: a first report.

J Nanosci Nanotechnol

Kannan AM, Renugopalakrishnan V, Filipek S, Li P, Audette GF, Munukutla L

Bio-batteries and bio-fuel cells: leveraging on electronic charge transfer proteins.

J Nanosci Nanotechnol

V. Renugopalakrishnan, A. M. Kannan, S. Srinivasan, V. Thavasi, S. Ramakrishna, P. Li, A. Mershin, S. Filipek, A. Kumar, J. Dutta, A. Jaya, L. Munukutla, S. Velumani, G. F. Audette

“Nanomaterials for Energy Convertion Applications”

\"Nanomaterials for Energy Storage Applications\"

S. Filipek

“Bioinformatyka strukturalna białek transbłonowych”


Klejman ME, Gruszczynska-Biegala J, Skibinska-Kijek A, Wisniewska MB, Misztal K, Blazejczyk M, Bojarski L, Kuznicki J.

Expression of STIM1 in brain and puncta-like co-localization of STIM1 and ORAI1 upon depletion of Ca(2+) store in neurons.

Neurochem Int

Skibinska-Kijek A, Wisniewska MB, Gruszczynska-Biegala J, Methner A, Kuznicki J

Immunolocalization of STIM1 in the mouse brain.

Acta Neurobiol Exp (Wars)

Bojarski L, Pomorski P, Szybinska A, Drab M, Skibinska-Kijek A, Gruszczynska-Biegala J, Kuznicki J

Presenilin-dependent expression of STIM proteins and dysregulation of capacitative Ca2+ entry in familial Alzheimer's disease.

Biochim Biophys Acta

Sokolowska M, Czapinska H, Bochtler M

Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA

Nucleic Acids Res

Majorek KA, Bujnicki JM

Modeling of Escherichia coli Endonuclease V structure in complex with DNA.

J Mol Model

Fink G, Hajdo L, Skowronek KJ, Reuther C, Kasprzak AA, Diez S

The mitotic kinesin-14 Ncd drives directional microtubule-microtubule sliding.

Nat Cell Biol

Czerwoniec A, Dunin-Horkawicz S, Purta E, Kaminska KH, Kasprzak JM, Bujnicki JM, Grosjean H, Rother K

MODOMICS: a database of RNA modification pathways. 2008 update

Nucleic Acids Res

Nakonieczna J, Kaczorowski T, Obarska-Kosinska A, Bujnicki JM

Functional analysis of MmeI from methanol utilizer Methylophilus methylotrophus, a subtype IIC restriction-modification enzyme related to type I enzymes.

Appl Environ Microbiol

Kennaway CK, Obarska-Kosinska A, White JH, Tuszynska I, Cooper LP, Bujnicki JM, Trinick J, Dryden DT

The structure of M.EcoKI Type I DNA methyltransferase with a DNA mimic antirestriction protein

Nucleic Acids Res

Pierechod M, Nowak A, Saari A, Purta E, Bujnicki JM, Konieczny I

Conformation of a plasmid replication initiator protein affects its proteolysis by ClpXP system

Protein Sci

Matsumoto Y, Oota H, Asaoka Y, Nishina H, Watanabe K, Bujnicki JM, Oda S, Kawamura S, Mitani H

Medaka: a promising model animal for comparative population genomics.

BMC Res Notes

Bauer RA, Rother K, Moor P, Reinert K, Steinke T, Bujnicki JM

Fast Structural Alignment of Biomolecules Using a Hash Table, N-Grams and String Descriptors


Purta E, O'Connor M, Bujnicki JM, Douthwaite S

YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA.

Mol Microbiol

Pawłowski M, Lasica AM, Jagusztyn-Krynicka EK, Bujnicki JM

AAN82231 protein from uropathogenic E. coli CFT073 is a close paralog of DsbB enzymes and does not belong to the DsbI family

Pol J Microbiol

Zylicz-Stachula A, Bujnicki JM, Skowron PM

Cloning and analysis of a bifunctional methyltransferase/restriction endonuclease TspGWI, the prototype of a Thermus sp. enzyme family.

BMC Mol Biol

Palfi Z, Jaé N, Preusser C, Kaminska KH, Bujnicki JM, Lee JH, Günzl A, Kambach C, Urlaub H, Bindereif A

SMN-assisted assembly of snRNP-specific Sm cores in trypanosomes.

Genes Dev

Pena V, Jovin SM, Fabrizio P, Orlowski J, Bujnicki JM, Lührmann R, Wahl MC

Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase.

Mol Cell

Kolmos E, Nowak M, Werner M, Fischer K, Schwarz G, Mathews S, Schoof H, Nagy F, Bujnicki JM, Davis SJ

Integrating ELF4 into the circadian system through combined structural and functional studies.


Leski TA, Caswell CC, Pawlowski M, Klinke DJ, Bujnicki JM, Hart SJ, Lukomski S

Identification and classification of bcl genes and proteins of Bacillus cereus group organisms and their application in Bacillus anthracis detection and fingerprinting.

Appl Environ Microbiol

Szymańska Z, Urbański J, Marciniak-Czochra A

Mathematical modelling of the influence of heat shock proteins on cancer invasion of tissue.

J Math Biol

Walerych D, Olszewski MB, Gutkowska M, Helwak A, Zylicz M, Zylicz A

Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions.


Narayan V, Eckert M, Zylicz A, Zylicz M, Ball KL

Cooperative regulation of the interferon regulatory factor-1 tumor suppressor protein by core components of the molecular chaperone machinery

J Biol Chem

Jaworski J, Kapitein LC, Gouveia SM, Dortland BR, Wulf PS, Grigoriev I, Camera P, Spangler SA, Di Stefano P, Demmers J, Krugers H, Defilippi P, Akhmanova A, Hoogenraad CC

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity.


Blazejczyk M, Sobczak A, Debowska K, Wisniewska MB, Kirilenko A, Pikula S, Jaworski J, Kuznicki J, Wojda U.

Biochemical characterization and expression analysis of a novel EF-hand Ca2+ binding protein calmyrin2 (Cib2) in brain indicates its function in NMDA receptor mediated Ca2+ signaling.

Arch Biochem Biophys

Nowotny M, Yang W

Structural and functional modules in RNA interference

Curr Opin Struct Biol

Nowotny M

Retroviral integrase superfamily: the structural perspective.


Rashid S, Pilecka I, Torun A, Olchowik M, Bielinska B, Miaczynska M

Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription.

J Biol Chem

Pyrzynska B, Pilecka I, Miaczynska M

Endocytic proteins in the regulation of nuclear signaling, transcription and tumorigenesis

Mol Oncol

Park PS, Sapra KT, Jastrzebska B, Maeda T, Maeda A, Pulawski W, Kono M, Lem J, Crouch RK, Filipek S, Müller DJ, Palczewski K

Modulation of molecular interactions and function by rhodopsin palmitylation


J.S. Jaworski, A. Kosson, S. Filipek, M. Kolinski, D. Kuck

Properties of Radical Anions of Triptindanones and Indanones: Electronic Communication and Stability of Ion Pairs Containing Lithium Cations

J. Phys. Chem. C

Puzianowska-Kuznicka M, Kuznicki J.

The ER and ageing II: calcium homeostasis.

Ageing Res Rev

Wawrzynow B, Pettersson S, Zylicz A, Bramham J, Worrall E, Hupp TR, Ball KL

A function for the RING finger domain in the allosteric control of MDM2 conformation and activity.

J Biol Chem

Szymańska Z, Zylicz M

Mathematical modeling of heat shock protein synthesis in response to temperature change.

J Theor Biol


Geremek M, Schoenmaker F, Zietkiewicz E, Pogorzelski A, Diehl S, Wijmenga C, Witt M

Sequence analysis of 21 genes located in the Kartagener syndrome linkage region on chromosome 15q

Eur J Hum Genet

Dawidowska M, Jółkowska J, Szczepański T, Derwich K, Wachowiak J, Witt M

Implementation of the standard strategy for identification of Ig/TCR targets for minimal residual disease diagnostics in B-cell precursor ALL pediatric patients: Polish experience

Arch Immunol Ther Exp (Warsz)

Tomat E, Nolan EM, Jaworski J, Lippard SJ

Organelle-specific zinc detection using zinpyr-labeled fusion proteins in live cells

J Am Chem Soc

Rylski M, Amborska R, Zybura K, Mioduszewska B, Michaluk P, Jaworski J, Kaczmarek L

Yin Yang 1 is a critical repressor of matrix metalloproteinase-9 expression in brain neurons

J Biol Chem

Jaworski J, Hoogenraad CC, Akhmanova A

Microtubule plus-end tracking proteins in differentiated mammalian cells.

Int J Biochem Cell Biol

Swiech L, Perycz M, Malik A, Jaworski J

Role of mTOR in physiology and pathology of the nervous system

Biochim Biophys Acta

Macias M

Injury induced dendritic plasticity in the mature central nervous system.

Acta Neurobiol Exp (Wars)

Urbanska M, Blazejczyk M, Jaworski J

Molecular basis of dendritic arborization

Acta Neurobiol Exp (Wars)

Mioduszewska B, Jaworski J, Szklarczyk AW, Klejman A, Kaczmarek L

Inducible cAMP early repressor (ICER)-evoked delayed neuronal death in the organotypic hippocampal culture

J Neurosci Res

Kubiak JZ, Ciemerych MA, Hupalowska A, Sikora-Polaczek M, Polanski Z

On the transition from the meiotic to mitotic cell cycle during early mouse development.

Int J Dev Biol

Miaczynska M, Stenmark H

Mechanisms and functions of endocytosis.

J Cell Biol

Kolinski M, Filipek S.

Molecular dynamics of mu opioid receptor complexes with agonists and antagonists

The Open Struct. Biol. J.

Jozwiak K, Krzysko KA, Bojarski L, Gacia M, Filipek S

Molecular models of the interface between anterior pharynx-defective protein 1 (APH-1) and presenilin involving GxxxG motifs


Bhatia P, Kolinski M, Moaddel R, Jozwiak K, Wainer IW

Determination and modelling of stereoselective interactions of ligands with drug transporters: a key dimension in the understanding of drug disposition


Stephen R, Filipek S, Palczewski K, Sousa MC

Ca2+ -dependent regulation of phototransduction.

Photochem Photobiol

Majewski T, Lee S, Jeong J, Yoon DS, Kram A, Kim MS, Tuziak T, Bondaruk J, Lee S, Park WS, Tang KS, Chung W, Shen L, Ahmed SS, Johnston DA, Grossman HB, Dinney CP, Zhou JH, Harris RA, Snyder C, Filipek S, Narod SA, Watson P, Lynch HT, Gazdar A, Bar-Eli M,

Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy.

Lab Invest

Erickson RP, Larson-Thomé K, Weberg L, Szybinska A, Mossakowska M, Styczynska M, Barcikowska M, Kuznicki J

Variation in NPC1, the gene encoding Niemann-Pick C1, a protein involved in intracellular cholesterol transport, is associated with Alzheimer disease and/or aging in the Polish population

Neurosci Lett

Winiarska M, Bil J, Wilczek E, Wilczynski GM, Lekka M, Engelberts PJ, Mackus WJ, Gorska E, Bojarski L, Stoklosa T, Nowis D, Kurzaj Z, Makowski M, Glodkowska E, Issat T, Mrowka P, Lasek W, Dabrowska-Iwanicka A, Basak GW, Wasik M, Warzocha K, Sinski M, Gaciong Z, Jakobisiak M, Parren PW, Golab J.

Statins impair antitumor effects of rituximab by inducing conformational changes of CD20.

PLoS Med

Mossakowska M, Barcikowska M, Broczek K, Grodzicki T, Klich-Raczka A, Kupisz-Urbanska M, Podsiadly-Marczykowska T, Sikora E, Szybinska A, Wieczorowska-Tobis K, Zyczkowska J, Kuznicki J

Polish Centenarians Programme. Multidisciplinary studies of successful ageing: aims, methods, and preliminary results

Exp Gerontol

Bojarski L, Herms J, Kuznicki J

Calcium dysregulation in Alzheimer's disease

Neurochem Int

Wojda U, Salinska E, Kuznicki J

Calcium ions in neuronal degeneration


Lanni C, Racchi M, Mazzini G, Ranzenigo A, Polotti R, Sinforiani E, Olivari L, Barcikowska M, Styczynska M, Kuznicki J, Szybinska A, Govoni S, Memo M, Uberti D

Conformationally altered p53: a novel Alzheimer's disease marker?

Mol Psychiatry

Zabka M, Leśniak W, Prus W, Kuźnicki J, Filipek A

Sgt1 has co-chaperone properties and is up-regulated by heat shock.

Biochem Biophys Res Commun

Filipek A, Michowski W, Kuznicki J

Involvement of S100A6 (calcyclin) and its binding partners in intracellular signaling pathways

Adv Enzyme Regul

Blazejczyk M, Wojda U

Factfile: Calmyrin 1 (review)

Calcium Binding Proteins

Szczepanowski RH, Carpenter MA, Czapinska H, Zaremba M, Tamulaitis G, Siksnys V, Bhagwat AS, Bochtler M

Central base pair flipping and discrimination by PspGI

Nucleic Acids Res

Tamulaitis G, Zaremba M, Szczepanowski RH, Bochtler M, Siksnys V

How PspGI, catalytic domain of EcoRII and Ecl18kI acquire specificities for different DNA targets

Nucleic Acids Res

Breer K, Wielgus-Kutrowska B, Hashimoto M, Hikishima S, Yokomatsu T, Szczepanowski RH, Bochtler M, Girstun A, Starón K, Bzowska A

Thermodynamic studies of interactions of calf spleen PNP with acyclic phosphonate inhibitors

Nucleic Acids Symp Ser (Oxf)

Sukackaite R, Grazulis S, Bochtler M, Siksnys V.

The recognition domain of the BpuJI restriction endonuclease in complex with cognate DNA at 1.3-A resolution

J Mol Biol

Lipka M, Filipek R, Bochtler M

Crystal structure and mechanism of the Staphylococcus cohnii virginiamycin B lyase (Vgb)


Maravić Vlahovicek G, Cubrilo S, Tkaczuk KL, Bujnicki JM

Modeling and experimental analyses reveal a two-domain structure and amino acids important for the activity of aminoglycoside resistance methyltransferase Sgm.

Biochim Biophys Acta

Vasu K, Saravanan M, Bujnicki JM, Nagaraja V

Structural integrity of the beta beta alpha-Metal finger motif is required for DNA binding and stable protein-DNA complex formation in R.KpnI.

Biochim Biophys Acta

Kaminska KH, Baraniak U, Boniecki M, Nowaczyk K, Czerwoniec A, Bujnicki JM

Structural bioinformatics analysis of enzymes involved in the biosynthesis pathway of the hypermodified nucleoside ms(2)io(6)A37 in tRNA.


Roovers M, Oudjama Y, Kaminska KH, Purta E, Caillet J, Droogmans L, Bujnicki JM

Sequence-structure-function analysis of the bifunctional enzyme MnmC that catalyses the last two steps in the biosynthesis of hypermodified nucleoside mnm5s2U in tRNA.


Kaminska KH, Bujnicki JM

Bacteriophage Mu Mom protein responsible for DNA modification is a new member of the acyltransferase superfamily.

Cell Cycle

Mittra B, Zamudio JR, Bujnicki JM, Stepinski J, Darzynkiewicz E, Campbell DA, Sturm NR

The TbMTr1 spliced leader RNA cap 1 2'-O-ribose methyltransferase from Trypanosoma brucei acts with substrate specificity

J Biol Chem

Feder M, Purta E, Koscinski L, Cubrilo S, Maravic Vlahovicek G, Bujnicki JM

Virtual screening and experimental verification to identify potential inhibitors of the ErmC methyltransferase responsible for bacterial resistance against macrolide antibiotics.


Bhagwat AS, Carpenter MA, Bujnicki JM

Is AID a monomer in solution?

DNA Repair (Amst)

Cymerman IA, Chung I, Beckmann BM, Bujnicki JM, Meiss G

EXOG, a novel paralog of Endonuclease G in higher eukaryotes.

Nucleic Acids Res

Sen TZ, Kloster M, Jernigan RL, Kolinski A, Bujnicki JM, Kloczkowski A

Predicting the complex structure and functional motions of the outer membrane transporter and signal transducer FecA.

Biophys J

Chua TK, Bujnicki JM, Tan TC, Huynh F, Patel BK, Sivaraman J

The structure of sucrose phosphate synthase from Halothermothrix orenii reveals its mechanism of action and binding mode.

Plant Cell

Roovers M, Kaminska KH, Tkaczuk KL, Gigot D, Droogmans L, Bujnicki JM

The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK).

Nucleic Acids Res

Orlowski J, Bujnicki JM

Structural and evolutionary classification of Type II restriction enzymes based on theoretical and experimental analyses.

Nucleic Acids Res

White J, Li Z, Sardana R, Bujnicki JM, Marcotte EM, Johnson AW

Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits.

Mol Cell Biol

Kosinski J, Plotz G, Guarné A, Bujnicki JM, Friedhoff P

The PMS2 subunit of human MutLalpha contains a metal ion binding domain of the iron-dependent repressor protein family.

J Mol Biol

Purta E, Kaminska KH, Kasprzak JM, Bujnicki JM, Douthwaite S

YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.


Pawlowski M, Gajda MJ, Matlak R, Bujnicki JM

MetaMQAP: a meta-server for the quality assessment of protein models.

BMC Bioinformatics

Sunita S, Tkaczuk KL, Purta E, Kasprzak JM, Douthwaite S, Bujnicki JM, Sivaraman J

Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes.

J Mol Biol

Obarska-Kosinska A, Taylor JE, Callow P, Orlowski J, Bujnicki JM, Kneale GG

HsdR subunit of the type I restriction-modification enzyme EcoR124I: biophysical characterisation and structural modelling.

J Mol Biol

Purta E, O\'Connor M, Bujnicki JM, Douthwaite S

YccW is the m5C methyltransferase specific for 23S rRNA nucleotide 1962

J Mol Biol

Gyrd-Hansen M, Darding M, Miasari M, Santoro MM, Zender L, Xue W, Tenev T, da Fonseca PC, Zvelebil M, Bujnicki JM, Lowe S, Silke J, Meier P

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis.

Nat Cell Biol

Orlowski J, Mebrhatu MT, Michiels CW, Bujnicki JM, Aertsen A

Mutational analysis and a structural model of methyl-directed restriction enzyme Mrr.

Biochem Biophys Res Commun

Guranowski A, Wojdyła AM, Pietrowska-Borek M, Bieganowski P, Khurs EN, Cliff MJ, Blackburn GM, Błaziak D, Stec WJ

Fhit proteins can also recognize substrates other than dinucleoside polyphosphates.


Sbroggiò M, Ferretti R, Percivalle E, Gutkowska M, Zylicz A, Michowski W, Kuznicki J, Accornero F, Pacchioni B, Lanfranchi G, Hamm J, Turco E, Silengo L, Tarone G, Brancaccio M.

The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1.


Stevens C, Pettersson S, Wawrzynow B, Wallace M, Ball K, Zylicz A, Hupp TR

ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1.


Zurawska A, Urbanski J, Bieganowski P

Hsp90n - An accidental product of a fortuitous chromosomal translocation rather than a regular Hsp90 family member of human proteome

Biochim Biophys Acta


Kołłajtis-Dołowy A, Pietruszka B, Kałuza J, Pawlińiska-Chmara R, Broczek K, Mossakowska M

The nutritional habits among centenarians living in Warsaw

Rocz Panstw Zakl Hig

Baranowska B, Wolinska-Witort E, Bik W, Baranowska-Bik A, Martynska L, Broczek K, Mossakowska M, Chmielowska M

Evaluation of neuroendocrine status in longevity

Neurobiol Aging

Wojda A, Zietkiewicz E, Witt M

Effects of age and gender on micronucleus and chromosome nondisjunction frequencies in centenarians and younger subjects


Jaworski J

ARF6 in the nervous system.

Eur J Cell Biol

Michaluk P, Kolodziej L, Mioduszewska B, Wilczynski GM, Dzwonek J, Jaworski J, Gorecki DC, Ottersen OP, Kaczmarek L

Beta-dystroglycan as a target for MMP-9, in response to enhanced neuronal activity.

J Biol Chem

Okulski P, Jay TM, Jaworski J, Duniec K, Dzwonek J, Konopacki FA, Wilczynski GM, Sánchez-Capelo A, Mallet J, Kaczmarek L

TIMP-1 abolishes MMP-9-dependent long-lasting long-term potentiation in the prefrontal cortex.

Biol Psychiatry

Pilecka I, Banach-Orlowska M, Miaczynska M

Nuclear functions of endocytic proteins

Eur J Cell Biol

Golan MP, Styczyńska M, Jóźwiak K, Walecki J, Maruszak A, Pniewski J, Lugiewicz R, Filipek S, Zekanowski C, Barcikowska M

Early-onset Alzheimer's disease with a de novo mutation in the presenilin 1 gene

Exp Neurol

Krzysko KA, Kolinski M, Filipek S.

Molecular modelling of the complex of oligomeric rhodopsin and its G protein.

J Phys Condens Matter

Lee S, Jeong J, Majewski T, Scherer SE, Kim MS, Tuziak T, Tang KS, Baggerly K, Grossman HB, Zhou JH, Shen L, Bondaruk J, Ahmed SS, Samanta S, Spiess P, Wu X, Filipek S, McConkey D, Bar-Eli M, Issa JP, Benedict WF, Czerniak B

Forerunner genes contiguous to RB1 contribute to the development of in situ neoplasia.

Proc Natl Acad Sci U S A

Park PS, Sapra KT, Koliński M, Filipek S, Palczewski K, Muller DJ

Stabilizing effect of Zn2+ in native bovine rhodopsin

J Biol Chem

Bojarski L, Lewandowicz A, Blazejczyk M, Sobczak A, Kuznicki J, Wojda U

Biochemical properties of endogenous presenilin 1 and presenilin 2 in cultured human B-lymphocytes

Clin Chem Lab Med

Leśniak W, Słomnicki ŁP, Kuźnicki J

Epigenetic control of the S100A6 (calcyclin) gene expression

J Invest Dermatol

Schneider G, Nieznanski K, Kilanczyk E,Bieganowski P, Kuznicki J, Filipek A

CacyBP/SIP interacts with tubulin in neuroblastoma NB2a cells and induces formation of globular tubulin assemblies

Biochim Biophys Acta

Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J,Filipek A

Hsp70 is a new target of Sgt1-an interaction modulated by S100A6

Biochem Biophys Res Commun

Wollmer MA, Sleegers K, Ingelsson M, Zekanowski C, Brouwers N, Maruszak A, Brunner F, Huynh KD, Kilander L, Brundin RM, Hedlund M, Giedraitis V, Glaser A, Engelborghs S, De Deyn PP, Kapaki E, Tsolaki M, Daniilidou M, Molyva D, Paraskevas GP, Thal DR, Barcikowska M, Kuznicki J, Lannfelt L, Van Broeckhoven C, Nitsch RM, Hock C, Papassotiropoulos A.

Association study of cholesterol-related genes in Alzheimer's disease


Bochtler M, Chojnowski G

The highest reflection intensity in a resolution shell

Acta Crystallogr A

Chojnowski G, Bochtler M

The statistics of the highest E value

Acta Crystallogr A

Firczuk M, Bochtler M

Folds and activities of peptidoglycan amidases

FEMS Microbiol Rev

Firczuk M, Bochtler M

Mutational analysis of peptidoglycan amidase MepA


Kaus-Drobek M, Czapinska H, Sokołowska M, Tamulaitis G, Szczepanowski RH, Urbanke C, Siksnys V, Bochtler M

Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically

Nucleic Acids Res

Sokolowska M, Kaus-Drobek M, Czapinska H, Tamulaitis G, Siksnys V, Bochtler M

Restriction endonucleases that resemble a component of the bacterial DNA repair machinery

Cell Mol Life Sci

Sokolowska M, Kaus-Drobek M, Czapinska H, Tamulaitis G, Szczepanowski RH, Urbanke C, Siksnys V, Bochtler M

Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA.

J Mol Biol

Tamulaitis G, Zaremba M, Szczepanowski RH, Bochtler M, Siksnys V

Nucleotide flipping by restriction enzymes analyzed by 2-aminopurine steady-state fluorescence

Nucleic Acids Res

Zamudio JR, Mittra B, Foldynová-Trantírková S, Zeiner GM, Lukes J, Bujnicki JM, Sturm NR, Campbell DA

The 2'-O-ribose methyltransferase for cap 1 of spliced leader RNA and U1 small nuclear RNA in Trypanosoma brucei

Mol Cell Biol

Tkaczuk KL, Dunin-Horkawicz S, Purta E, Bujnicki JM

Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.

BMC Bioinformatics

Sunita S, Purta E, Durawa M, Tkaczuk KL, Swaathi J, Bujnicki JM, Sivaraman J

Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC.

Nucleic Acids Res

Schäfer P, Cymerman IA, Bujnicki JM, Meiss G

Human lysosomal DNase IIalpha contains two requisite PLD-signature (HxK) motifs: evidence for a pseudodimeric structure of the active enzyme species.

Protein Sci

Sasin JM, Godzik A, Bujnicki JM

SURF'S UP! - protein classification by surface comparisons

J Biosci

Sabates-Bellver J, Van der Flier LG, de Palo M, Cattaneo E, Maake C, Rehrauer H, Laczko E, Kurowski MA, Bujnicki JM, Menigatti M, Luz J, Ranalli TV, Gomes V, Pastorelli A, Faggiani R, Anti M, Jiricny J, Clevers H, Marra G

Transcriptome profile of human colorectal adenomas.

Mol Cancer Res

Pietal MJ, Tuszynska I, Bujnicki JM

PROTMAP2D: visualization, comparison and analysis of 2D maps of protein structure.


Pena V, Liu S, Bujnicki JM, Lührmann R, Wahl MC

Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa.

Mol Cell

Ozanick SG, Bujnicki JM, Sem DS, Anderson JT

Conserved amino acids in each subunit of the heteroligomeric tRNA m1A58 Mtase from Saccharomyces cerevisiae contribute to tRNA binding.

Nucleic Acids Res

Orlowski J, Boniecki M, Bujnicki JM

I-Ssp6803I: the first homing endonuclease from the PD-(D/E)XK superfamily exhibits an unusual mode of DNA recognition


Miyazono K, Watanabe M, Kosinski J, Ishikawa K, Kamo M, Sawasaki T, Nagata K, Bujnicki JM, Endo Y, Tanokura M, Kobayashi I

Novel protein fold discovered in the PabI family of restriction enzymes.

Nucleic Acids Res

Liu Y, Li Z, Lin Q, Kosinski J, Seetharaman J, Bujnicki JM, Sivaraman J, Hew CL

Structure and evolutionary origin of Ca(2+)-dependent herring type II antifreeze protein.

PLoS One

Kudan EV, Brevnov MG, Subach OM, Rechkoblit OA, Buĭnitskiĭ IaM, Gromova ES

[Probing of contacts between EcoRII DNA methyltransferase and DNA using substrate analogs and molecular modeling].

Mol Biol (Mosk)

Kosinski J, Kubareva E, Bujnicki JM

A model of restriction endonuclease MvaI in complex with DNA: a template for interpretation of experimental data and a guide for specificity engineering.


Koscinski L, Feder M, Bujnicki JM

Identification of a missing sequence and functionally important residues of 16S rRNA:m(1)A1408 methyltransferase KamB that causes bacterial resistance to aminoglycoside antibiotics.

Cell Cycle

Jakubauskas A, Giedriene J, Bujnicki JM, Janulaitis A

Identification of a single HNH active site in type IIS restriction endonuclease Eco31I

J Mol Biol

Ibryashkina EM, Zakharova MV, Baskunov VB, Bogdanova ES, Nagornykh MO, Den\'mukhamedov MM, Melnik BS, Kolinski A, Gront D, Feder M, Solonin AS, Bujnicki JM

Type II restriction endonuclease R.Eco29kI is a member of the GIY-YIG nuclease superfamily.

BMC Struct Biol

Chovancová E, Kosinski J, Bujnicki JM, Damborský J

Phylogenetic analysis of haloalkane dehalogenases.


Schneider G, Nieznanski K, Kilanczyk E, Bieganowski P, Kuznicki J, Filipek A

CacyBP/SIP interacts with tubulin in neuroblastoma NB2a cells and induces formation of globular tubulin assemblies.

Biochim Biophys Acta

Wawrzynow B, Zylicz A, Wallace M, Hupp T, Zylicz M

MDM2 chaperones the p53 tumor suppressor.

J Biol Chem

Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J, Filipek A

Hsp70 is a new target of Sgt1--an interaction modulated by S100A6

Biochem Biophys Res Commun

Issat T, Nowis D, Legat M, Makowski M, Klejman MP, Urbanski J, Skierski J, Koronkiewicz M, Stoklosa T, Brzezinska A, Bil J, Gietka J, Jakóbisiak M, Golab J

Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.

Int J Oncol

Schneider G, Nieznanski K, Kilanczyk E, Bieganowski P, Kuznicki J, Filipek A

CacyBP/SIP interacts with tubulin in neuroblastoma NB2a cells and induces formation of globular tubulin assemblies.

Biochim Biophys Acta

Wawrzynow B, Zylicz A, Wallace M, Hupp T, Zylicz M

MDM2 chaperones the p53 tumor suppressor.

J Biol Chem

Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J, Filipek A

Hsp70 is a new target of Sgt1--an interaction modulated by S100A6.

Biochem Biophys Res Commun

Issat T, Nowis D, Legat M, Makowski M, Klejman MP, Urbanski J, Skierski J, Koronkiewicz M, Stoklosa T, Brzezinska A, Bil J, Gietka J, Jakóbisiak M, Golab J

Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.

Int J Oncol


Kupisz-Urbańska M, Broczek K, Mossakowska M

Physical activity in Polish centenarians

Gerontologia Polska

Mossakowska M, Broczek K, Rajska-Neumann A, Wieczorowska-Tobis K

How often and how much have Polish centenarians smoked?

Przegląd Lekarski

Pawlinska-Chmara R, Mossakowska M

Evaluation of teeth and dentures state of Polish centenarians

Ann Univ M. Curie-Sklodowska

Podkówka-Sieczka R, Niemir Z, Mossakowska M, Sawiński K, Wieczorowska-Tobis K

The analysis of the peripheral blood leukocytes in centenarians

Przegląd Lekarski

Styczyński A, Wieczorowska-Tobis K, Niemir Z, Podkówka R, Mossakowska M

Is there a link between the level of circulating IL-8 and cognitive impairment in centenarians?

Przegląd Lekarski

Wieczorowska-Tobis K, Niemir ZI, Podkówka R, Korybalska K, Mossakowska M, Breborowicz A

Can an increased level of circulating IL-8 be a predictor of human longevity?

Med Sci Monit

Wojda A, Zietkiewicz E, Mossakowska M, Pawłowski W, Skrzypczak K, Witt M

Correlation between the level of cytogenetic aberrations in cultured human lymphocytes and the age and gender of donors

J Gerontol A Biol Sci Med Sci

Pietruszka B, Kollajtis-Dolowy A, Szulc K, Kaluza J, Broczek K, Pawlinska-Chmara R, Mossakowska M

Characteristics of nutrition among centenarians living in Warsaw

Pol J Food Nutr Sci

Kempa K, Kłapcińska B, Mossakowska M, Broczek K, Sadowska-Krępa E, Derejczyk J, Kimsa E

Functional abilities and antioxidant defense status in female centenarians

Annales Universitatis Mariae Curie-Skłaodowska

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Wojcik M, Seidle HF, Bieganowski P, Brenner C

Glutamine-dependent NAD+ synthetase. How a two-domain, three-substrate enzyme avoids waste.

J Biol Chem

Jaworski J, Sheng M

The growing role of mTOR in neuronal development and plasticity

Mol Neurobiol

Nolan EM, Ryu JW, Jaworski J, Feazell RP, Sheng M, Lippard SJ

Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization.

J Am Chem Soc

Szymczak S, Kalita K, Jaworski J, Mioduszewska B, Savonenko A, Markowska A, Merchenthaler I, Kaczmarek L

Increased estrogen receptor beta expression correlates with decreased spine formation in the rat hippocampus


Cieplak M, Filipek S, Janovjak H, Krzyśko KA

Pulling single bacteriorhodopsin out of a membrane: Comparison of simulation and experiment.

Biochim Biophys Acta

Jozwiak K, Zekanowski C, Filipek S

Linear patterns of Alzheimer's disease mutations along alpha-helices of presenilins as a tool for PS-1 model construction

J Neurochem

Modzelewska A, Filipek S, Palczewski K, Park PS

Arrestin interaction with rhodopsin: conceptual models.

Cell Biochem Biophys

Tanuj Sapra K, Park PS, Filipek S, Engel A, Müller DJ, Palczewski K

Detecting molecular interactions that stabilize native bovine rhodopsin

J Mol Biol

Zekanowski C, Golan MP, Krzyśko KA, Lipczyńska-Łojkowska W, Filipek S, Kowalska A, Rossa G, Pepłońska B, Styczyńska M, Maruszak A, Religa D, Wender M, Kulczycki J, Barcikowska M, Kuźnicki J.

Two novel presenilin 1 gene mutations connected with frontotemporal dementia-like clinical phenotype: genetic and bioinformatic assessment.

Exp Neurol.

Zhu L, Imanishi Y, Filipek S, Alekseev A, Jastrzebska B, Sun W, Saperstein DA, Palczewski K

Autosomal recessive retinitis pigmentosa and E150K mutation in the opsin gene.

J Biol Chem

Jaworski JS, Cembor M, Koliński M

Electrostatic model of bond dissociation energies in polyhalogen methanes

J Phys Org Chem

Groves P, Palczewska M, Kuznicki J

Calretinin, an EF-hand calcium-binding proteins, binds zinc and Cooper

Calcium Binding Proteins

Leśniak W, Kuźnicki J

Binding and functional characteristics of two E-box motifs within the S100A6 (calcyclin) gene promoter.

J Cell Biochem

Spiechowicz M, Bernstein HG, Dobrowolny H, Leśniak W, Mawrin C, Bogerts B, Kuźnicki J, Filipek A

Density of Sgt1-immunopositive neurons is decreased in the cerebral cortex of Alzheimer's disease brain.

Neurochem Int

Baranowska B, Bik W, Baranowska-Bik A, Wolinska-Witort E, Szybinska A, Martynska L, Chmielowska M

Neuroendocrine control of metabolic homeostasis in Polish centenarians

J Physiol Pharmacol

Bik W, Baranowska-Bik A, Wolinska-Witort E, Martynska L, Chmielowska M, Szybinska A, Broczek K, Baranowska B

The relationship between adiponectin levels and metabolic status in centenarian, early elderly, young and obese women

Neuro Endocrinol Lett

Blazejczyk M, Wojda U, Sobczak A, Spilker C, Bernstein HG, Gundelfinger ED, Kreutz MR, Kuznicki J

Ca2+-independent binding and cellular expression profiles question a significant role of calmyrin in transduction of Ca2+-signals to Alzheimer's disease-related presenilin 2 in forebrain

Biochim Biophys Acta

Bochtler M, Szczepanowski RH, Tamulaitis G, Grazulis S, Czapinska H, Manakova E, Siksnys V

Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease


Zegers I, Gigot D, van Vliet F, Tricot C, Aymerich S, Bujnicki JM, Kosinski J, Droogmans L

Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.

Nucleic Acids Res

Zamudio JR, Mittra B, Zeiner GM, Feder M, Bujnicki JM, Sturm NR, Campbell DA

Complete cap 4 formation is not required for viability in Trypanosoma brucei.

Eukaryot Cell

Tkaczuk KL, Obarska A, Bujnicki JM

Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis.

BMC Evol Biol

Skowronek KJ, Kosinski J, Bujnicki JM

Theoretical model of restriction endonuclease HpaI in complex with DNA, predicted by fold recognition and validated by site-directed mutagenesis.


Sikora E, Bielak-Zmijewska A, Magalska A, Piwocka K, Mosieniak G, Kalinowska M, Widlak P, Cymerman IA, Bujnicki JM

Curcumin induces caspase-3-dependent apoptotic pathway but inhibits DNA fragmentation factor 40/caspase-activated DNase endonuclease in human Jurkat cells.

Mol Cancer Ther

Samaranayake M, Bujnicki JM, Carpenter M, Bhagwat AS

Evaluation of molecular models for the affinity maturation of antibodies: roles of cytosine deamination by AID and DNA repair.

Chem Rev

Purta E, van Vliet F, Tkaczuk KL, Dunin-Horkawicz S, Mori H, Droogmans L, Bujnicki JM

The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase.

BMC Mol Biol

Obarska A, Blundell A, Feder M, Vejsadová S, Sisáková E, Weiserová M, Bujnicki JM, Firman K

Structural model for the multisubunit Type IC restriction-modification DNA methyltransferase M.EcoR124I in complex with DNA.

Nucleic Acids Res

Mikula M, Karczmarski J, Dzwonek A, Rubel T, Hennig E, Dadlez M, Bujnicki JM, Bomsztyk K, Ostrowski J

Casein kinases phosphorylate multiple residues spanning the entire hnRNP K length.

Biochim Biophys Acta

Metz J, Wächter A, Schmidt B, Bujnicki JM, Schwappach B

The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol.

J Biol Chem

Klimek-Tomczak K, Mikula M, Dzwonek A, Paziewska A, Karczmarski J, Hennig E, Bujnicki JM, Bragoszewski P, Denisenko O, Bomsztyk K, Ostrowski J

Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa.

Br J Cancer

Han R, Caswell CC, Lukomska E, Keene DR, Pawlowski M, Bujnicki JM, Kim JK, Lukomski S

Binding of the low-density lipoprotein by streptococcal collagen-like protein Scl1 of Streptococcus pyogenes.

Mol Microbiol

Gros L, Renodon-Cornière A, de Saint Vincent BR, Feder M, Bujnicki JM, Jacquemin-Sablon A

Characterization of prmt7alpha and beta isozymes from Chinese hamster cells sensitive and resistant to topoisomerase II inhibitors.

Biochim Biophys Acta

Godlewska R, Dzwonek A, Mikuła M, Ostrowski J, Pawłowski M, Bujnicki JM, Jagusztyn-Krynicka EK

Helicobacter pylori protein oxidation influences the colonization process.

Int J Med Microbiol

Gabant G, Auxilien S, Tuszynska I, Locard M, Gajda MJ, Chaussinand G, Fernandez B, Dedieu A, Grosjean H, Golinelli-Pimpaneau B, Bujnicki JM, Armengaud J

THUMP from archaeal tRNA:m22G10 methyltransferase, a genuine autonomously folding domain.

Nucleic Acids Res

Dunin-Horkawicz S, Feder M, Bujnicki JM

Phylogenomic analysis of the GIY-YIG nuclease superfamily.

BMC Genomics

Cymerman IA, Obarska A, Skowronek KJ, Lubys A, Bujnicki JM

Identification of a new subfamily of HNH nucleases and experimental characterization of a representative member, HphI restriction endonuclease


Chiang PK, Bujnicki JM, Su X, Lanar DE

Malaria: therapy, genes and vaccines.

Curr Mol Med

Carpenter M, Divvela P, Pingoud V, Bujnicki J, Bhagwat AS

Sequence-dependent enhancement of hydrolytic deamination of cytosines in DNA by the restriction enzyme PspGI.

Nucleic Acids Res

Bujnicki JM

Protein-structure prediction by recombination of fragments.


Bheemanaik S, Bujnicki JM, Nagaraja V, Rao DN

Functional analysis of amino acid residues at the dimerisation interface of KpnI DNA methyltransferase.

Biol Chem

Dunin-Horkawicz S, Czerwoniec A, Gajda MJ, Feder M, Grosjean H, Bujnicki JM

MODOMICS: a database of RNA modification pathways.

Nucleic Acids Res

Kudla G, Lipinski L, Caffin F, Helwak A, Zylicz M

High guanine and cytosine content increases mRNA levels in mammalian cells

PLoS Biol

Galazka G, Stasiolek M, Walczak A, Jurewicz A, Zylicz A, Brosnan CF, Raine CS, Selmaj KW

Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis.

J Immunol

Bieganowski P, Seidle HF, Wojcik M, Brenner C

Synthetic lethal and biochemical analyses of NAD and NADH kinases in Saccharomyces cerevisiae establish separation of cellular functions.

J Biol Chem

Wojcik M, Seidle HF, Bieganowski P, Brenner C

Glutamine-dependent NAD+ synthetase. How a two-domain, three-substrate enzyme avoids waste.

J Biol Chem

Kudla G, Lipinski L, Caffin F, Helwak A, Zylicz M

High guanine and cytosine content increases mRNA levels in mammalian cells

PLoS Biol

Galazka G, Stasiolek M, Walczak A, Jurewicz A, Zylicz A, Brosnan CF, Raine CS, Selmaj KW

Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis.

J Immunol


Jólkowska J, Pieczonka A, Strabel T, Boruczkowski D, Wachowiak J, Bader P, Witt M

Hematopoietic chimerism after allogeneic stem cell transplantation: a comparison of quantitative analysis by automated DNA sizing and fluorescent in situ hybridization

BMC Blood Disord

Broczek KM, Pawlińska-Chmara R, Kupisz-Urbańska M, Mossakowska M

Anthropometric chest structure of Polish centenarians

J Physiol Pharmacol

Filipek S

Organization of rhodopsin molecules in native membranes of rod cells--an old theoretical model compared to new experimental data.

J Mol Model

Filipek S, Modzelewska A, Krzysko KA

Functional oligomers of rhodopsin – a G protein-coupled receptor template

Joint Meeting on Medical Chemistry

Sokal I, Dupps WJ, Grassi MA, Brown J Jr, Affatigato LM, Roychowdhury N, Yang L, Filipek S, Palczewski K, Stone EM, Baehr W

A novel GCAP1 missense mutation (L151F) in a large family with autosomal dominant cone-rod dystrophy (adCORD)

Invest Ophthalmol Vis Sci

Bernstein HG, Blazejczyk M, Rudka T, Gundelfinger ED, Dobrowolny H, Bogerts B, Kreutz MR, Kuznicki J, Wojda U

The Alzheimer disease-related calcium-binding protein Calmyrin is present in human forebrain with an altered distribution in Alzheimer's as compared to normal ageing brains

Neuropathol Appl Neurobiol

Bhattacharya S, Lee YT, Michowski W, Jastrzebska B, Filipek A, Kuznicki J, Chazin WJ

The modular structure of SIP facilitates its role in stabilizing multiprotein assemblies


Leśniak W, Szczepańska A, Kuźnicki J.

Calcyclin (S100A6) expression is stimulated by agents evoking oxidative stress via the antioxidant response element.

Biochim Biophys Acta

Palczewska M, Batta G, Groves P, Linse S, Kuznicki J

Characterization of calretinin I-II as an EF-hand, Ca2+, H+-sensing domain

Protein Sci

Puzianowska-Kuznicka M, Kuznicki J.

Genetic alterations in accelerated ageing syndromes. Do they play a role in natural ageing?

Int J Biochem Cell Biol

Sobczak A, Blazejczyk M, Piszczek G, Zhao G, Kuznicki J, Wojda U.

Calcium-binding calmyrin forms stable covalent dimers in vitro, but in vivo is found in monomeric form.

Acta Biochim Pol

Zekanowski C, Religa D, Safranow K, Maruszak A, Dziedziejko V, Styczyńska M, Gacia M, Golan M, Pepłońska B, Chlubek D, Kuźnicki J, Barcikowska M

The -22c/t polymorphism in presenilin 1 gene is not connected with late-onset and early-onset familial Alzheimer's disease in Poland

J Neural Transm

Azim MK, Goehring W, Song HK, Ramachandran R, Bochtler M, Goettig P

Characterization of the HslU chaperone affinity for HslV protease

Protein Sci

Dandanell G,Szczepanowski RH, Kierdaszuk B, Shugar D, Bochtler M

Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene

J Mol Biol

Filipek R, Potempa J, Bochtler M

A comparison of staphostatin B with standard mechanism serine protease inhibitors

J Biol Chem

Firczuk M, Mucha A, Bochtler M

Crystal structures of active LytM

J Mol Biol

Grazulis S, Manakova E, Roessle M, Bochtler M, Tamulaitiene G, Huber R, Siksnys V

Structure of the metal-independent restriction enzyme BfiI reveals fusion of a specific DNA-binding domain with a nonspecific nuclease.

Proc Natl Acad Sci U S A

Groll M, Bochtler M, Brandstetter H, Clausen T, Huber R

Molecular machines for protein degradation.


Korza HJ, Bochtler M

Pseudomonas aeruginosa LD-carboxypeptidase, a serine peptidase with a Ser-His-Glu triad and a nucleophilic elbow.

J Biol Chem

Odintsov SG, Sabała I, Bourenkov G, Rybin V, Bochtler M

Staphylococcus aureus aminopeptidase S is a founding member of a new peptidase clan

J Biol Chem

Odintsov SG, Sabała I, Bourenkov G, Rybin V, Bochtler M

Substrate access to the active sites in aminopeptidase T, a representative of a new metallopeptidase clan.

J Mol Biol

Szczepanowski RH, Filipek R, Bochtler M

Crystal structure of a fragment of mouse ubiquitin-activating enzyme.

J Biol Chem

Potempa J, Golonka E, Filipek R, Shaw LN

Fighting an enemy within: cytoplasmic inhibitors of bacterial cysteine proteases

Mol Microbiol

Marcyjaniak M, Odintsov SG, Sabala I, Bochtler M

Peptydoglycan amidase MepA is a LAS metallopeptidase

J Biol Chem

Radlińska M, Piekarowicz A, Galimand M, Bujnicki JM

Cloning and preliminary characterization of a GATC-specific beta2-class DNA:m6A methyltransferase encoded by transposon Tn1549 from Enterococcus spp.

Pol J Microbiol

Radlinska M, Kondrzycka-Dada A, Piekarowicz A, Bujnicki JM

Identification of amino acids important for target recognition by the DNA:m5C methyltransferase M.NgoPII by alanine-scanning mutagenesis of residues at the protein-DNA interface.


Raczko AM, Bujnicki JM, Pawlowski M, Godlewska R, Lewandowska M, Jagusztyn-Krynicka EK

Characterization of new DsbB-like thiol-oxidoreductases of Campylobacter jejuni and Helicobacter pylori and classification of the DsbB family based on phylogenomic, structural and functional criteria.


Purushothaman SK, Bujnicki JM, Grosjean H, Lapeyre B

Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA.

Mol Cell Biol

Kosinski J, Steindorf I, Bujnicki JM, Giron-Monzon L, Friedhoff P

Analysis of the quaternary structure of the MutL C-terminal domain.

J Mol Biol

Kosinski J, Gajda MJ, Cymerman IA, Kurowski MA, Pawlowski M, Boniecki M, Obarska A, Papaj G, Sroczynska-Obuchowicz P, Tkaczuk KL, Sniezynska P, Sasin JM, Augustyn A, Bujnicki JM, Feder M

FRankenstein becomes a cyborg: the automatic recombination and realignment of fold recognition models in CASP6.


Tkaczuk KL, Bujnicki JM, Bialkowska A, Bielecki S, Turkiewicz M, Cieslinski H, Kur J

Molecular modeling of a psychrophilic β-galactosidase

Biocatal Biotransform

Radlińska M, Piekarowicz A, Galimand M, Bujnicki JM

Cloning and preliminary characterization of a GATC-specific beta2-class DNA:m6A methyltransferase encoded by transposon Tn1549 from Enterococcus spp.

Pol J Microbiol

Radlinska M, Kondrzycka-Dada A, Piekarowicz A, Bujnicki JM

Identification of amino acids important for target recognition by the DNA:m5C methyltransferase M.NgoPII by alanine-scanning mutagenesis of residues at the protein-DNA interface.


Raczko AM, Bujnicki JM, Pawlowski M, Godlewska R, Lewandowska M, Jagusztyn-Krynicka EK

Characterization of new DsbB-like thiol-oxidoreductases of Campylobacter jejuni and Helicobacter pylori and classification of the DsbB family based on phylogenomic, structural and functional criteria.


Purta E, van Vliet F, Tricot C, De Bie LG, Feder M, Skowronek K, Droogmans L, Bujnicki JM

Sequence-structure-function relationships of a tRNA (m7G46) methyltransferase studied by homology modeling and site-directed mutagenesis.


Purushothaman SK, Bujnicki JM, Grosjean H, Lapeyre B

Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA.

Mol Cell Biol

Pingoud V, Sudina A, Geyer H, Bujnicki JM, Lurz R, Lüder G, Morgan R, Kubareva E, Pingoud A

Specificity changes in the evolution of type II restriction endonucleases: a biochemical and bioinformatic analysis of restriction enzymes that recognize unrelated sequences

J Biol Chem

Pingoud V, Geyer H, Geyer R, Kubareva E, Bujnicki JM, Pingoud A

Identification of base-specific contacts in protein-DNA complexes by photocrosslinking and mass spectrometry: a case study using the restriction endonuclease SsoII

Mol Biosyst

Pawlak SD, Radlinska M, Chmiel AA, Bujnicki JM, Skowronek KJ

Inference of relationships in the 'twilight zone' of homology using a combination of bioinformatics and site-directed mutagenesis: a case study of restriction endonucleases Bsp6I and PvuII

Nucleic Acids Res

Kosinski J, Steindorf I, Bujnicki JM, Giron-Monzon L, Friedhoff P

Analysis of the quaternary structure of the MutL C-terminal domain.

J Mol Biol

Kosinski J, Feder M, Bujnicki JM

The PD-(D/E)XK superfamily revisited: identification of new members among proteins involved in DNA metabolism and functional predictions for domains of (hitherto) unknown function.

BMC Bioinformatics

Koliński A, Bujnicki JM

Generalized protein structure prediction based on combination of fold-recognition with de novo folding and evaluation of models.


Ishikawa K, Watanabe M, Kuroita T, Uchiyama I, Bujnicki JM, Kawakami B, Tanokura M, Kobayashi I

Discovery of a novel restriction endonuclease by genome comparison and application of a wheat-germ-based cell-free translation assay: PabI (5'-GTA/C) from the hyperthermophilic archaeon Pyrococcus abyssi

Nucleic Acids Res

Feder M, Bujnicki JM

Identification of a new family of putative PD-(D/E)XK nucleases with unusual phylogenomic distribution and a new type of the active site.

BMC Genomics

Cymerman IA, Meiss G, Bujnicki JM

DNase II is a member of the phospholipase D superfamily.


Chmiel AA, Radlinska M, Pawlak SD, Krowarsch D, Bujnicki JM, Skowronek KJ

A theoretical model of restriction endonuclease NlaIV in complex with DNA, predicted by fold recognition and validated by site-directed mutagenesis and circular dichroism spectroscopy.

Protein Eng Des Sel

Chmiel AA, Bujnicki JM, Skowronek KJ

A homology model of restriction endonuclease SfiI in complex with DNA

BMC Struct Biol

Bujnicki J.M.

Protein structure prediction: Boltzmann and Darwin (in Polish)


Armalyte E, Bujnicki JM, Giedriene J, Gasiunas G, Kosiński J, Lubys A

Mva1269I: a monomeric type IIS restriction endonuclease from Micrococcus varians with two EcoRI- and FokI-like catalytic domains.

J Biol Chem

Klejman MP, Zhao X, van Schaik FM, Herr W, Timmers HT

Mutational analysis of BTAF1-TBP interaction: BTAF1 can rescue DNA-binding defective TBP mutants.

Nucleic Acids Res

Ilyushik E, Pryce DW, Walerych D, Riddell T, Wakeman JA, McInerny CJ, McFarlane RJ

Psc3 cohesin of Schizosaccharomyces pombe: cell cycle analysis and identification of three distinct isoforms.

Biol Chem

Bucko-Justyna M, Lipinski L, Burgering BM, Trzeciak L

Characterization of testis-specific serine-threonine kinase 3 and its activation by phosphoinositide-dependent kinase-1-dependent signalling.



Geremek M, Witt M

Primary ciliary dyskinesia: genes, candidate genes and chromosomal regions

J Appl Genet

Krawczyński MR, Dmeńska H, Witt M

Apparent X-linked primary ciliary dyskinesia associated with retinitis pigmentosa and a hearing loss

J Appl Genet

Krawczyński MR, Witt M

PCD and RP: X-linked inheritance of both disorders?

Pediatr Pulmonol

Lubka M, Wojda A, Witt M

Micronuclei in human cells – formation, contents, diagnostic and prognostic application

Postępy Biol Kom

Wieczorowska-Tobis K, Niemir ZI, Guzik P, Mossakowska M

Kidney function estimated with different formulas in centenarians

Rocz Akad Med Bialymst

Zyczkowska J, Klich-Raczka A, Mossakowska M, Gasowski J, Wieczorowska-Tobis K, Grodzicki T

Blood pressure in centenarians in Poland

J Hum Hypertens

Filipek S, Krzysko KA , Fotiadis D, Liang Y, Saperstein DA, Engel A, Palczewski K

A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface

Photochem Photobiol Sci

Fotiadis D, Liang Y, Filipek S, Saperstein DA, Engel A, Palczewski K

The G protein-coupled receptor rhodopsin in the native membrane


Imanishi Y, Yang L, Sokal I, Filipek S, Palczewski K, Baehr W

Diversity of guanylate cyclase-activating proteins (GCAPs) in teleost fish: characterization of three novel GCAPs (GCAP4, GCAP5, GCAP7) from zebrafish (Danio rerio) and prediction of eight GCAPs (GCAP1-8) in pufferfish (

J Mol Evol

Jastrzebska B, Maeda T, Zhu L, Fotiadis D, Filipek S, Engel A, Stenkamp RE, Palczewski K

Functional characterization of rhodopsin monomers and dimers in detergents

J Biol Chem

Liang Y, Fotiadis D, Maeda T, Maeda A, Modzelewska A, Filipek S, Saperstein DA, Engel A, Palczewski K

Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice

J Biol Chem

Park PS, Filipek S, Wells JW, Palczewski K

Oligomerization of G protein-coupled receptors: past, present, and future.


Suda K, Filipek S, Palczewski K, Engel A, Fotiadis D

The supramolecular structure of the GPCR rhodopsin in solution and native disc membranes.

Mol Membr Biol

Zhu L, Jang GF, Jastrzebska B, Filipek S, Pearce-Kelling SE, Aguirre GD, Stenkamp RE, Acland GM, Palczewski K

A naturally occurring mutation of the opsin gene (T4R) in dogs affects glycosylation and stability of the G protein-coupled receptor.

J Biol Chem

Billing-Marczak K, Ziemińska E, Leśniak W, Łazarewicz JW, Kuźnicki J

Calretinin gene promoter activity is differently regulated in neurons and cancer cells. Role of AP2-like cis element and zinc ions

Biochim Biophys Acta

Lee YT, Jacob J, Michowski W, Nowotny M, Kuznicki J, Chazin WJ.

Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain.

J Biol Chem.

Wojda U.

Gene therapy of hematopoietic cells: development of strategies and vectors. (in Polish)

Postepy Biol Kom

Zekanowski C, Pepłońska B, Styczyńska M, Religa D, Pfeffer A, Czyzewski K, Gabryelewicz T, Szybińska A, Kijanowska-Haładyna B, Kotapka-Minc S, Łuczywek E, Barczak A, Wasiak B, Chodakowska-Zebrowska M, Przekop I, Kuźnicki J, Barcikowska M

The E318G substitution in PSEN1 gene is not connected with Alzheimer's disease in a large Polish cohort.

Neurosci Lett

Zekanowski C, Religa D, Graff C, Filipek S, Kuźnicki J

Genetic aspects of Alzheimer's disease

Acta Neurobiol Exp (Wars)

Brzezińska A, Magalska A, Szybińska A, Sikora E

Proliferation and apoptosis of human CD8(+)CD28(+) and CD8(+)CD28(-) lymphocytes during aging

Exp Gerontol

Marcyjaniak M, Odintsov SG, Sabala I, Bochtler M

Peptidoglycan amidase MepA is a LAS metallopeptidase.

J Biol Chem

Bochtler M, Odintsov SG, Marcyjaniak M, Sabala I

Similar active sites in lysostaphins and D-Ala-D-Ala metallopeptidases.

Protein Sci

Filipek R, Szczepanowski R, Sabat A, Potempa J, Bochtler M

Prostaphopain B structure: a comparison of proregion-mediated and staphostatin-mediated protease inhibition


Marcyjaniak M, Odintsov SG, Sabala I, Bochtler M

Peptidoglycan amidase MepA is a LAS metallopeptidase

J Biol Chem

Odintsov SG, Sabala I, Marcyjaniak M, Bochtler M

Latent LytM at 1.3A resolution

J Mol Biol

Golonka E, Filipek R, Sabat A, Sinczak A, Potempa J

Genetic characterization of staphopain genes in Staphylococcus aureus

Biol Chem

Ye X, O\'Neil PK, Foster AN, Gajda MJ, Kosinski J, Kurowski MA, Bujnicki JM, Friedman AM, Bailey-Kellogg C

Probabilistic cross-link analysis and experiment planning for high-throughput elucidation of protein structure.

Protein Sci

Schäfer P, Scholz SR, Gimadutdinow O, Cymerman IA, Bujnicki JM, Ruiz-Carrillo A, Pingoud A, Meiss G

Structural and functional characterization of mitochondrial EndoG, a sugar non-specific nuclease which plays an important role during apoptosis.

J Mol Biol

Sasin JM, Bujnicki JM

COLORADO3D, a web server for the visual analysis of protein structures.

Nucleic Acids Res

Saravanan M, Bujnicki JM, Cymerman IA, Rao DN, Nagaraja V

Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily.

Nucleic Acids Res

Roovers M, Wouters J, Bujnicki JM, Tricot C, Stalon V, Grosjean H, Droogmans L

A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase

Nucleic Acids Res

Potluri S, Khan AA, Kuzminykh A, Bujnicki JM, Friedman AM, Bailey-Kellogg C

Geometric analysis of cross-linkability for protein fold discrimination.

Pac Symp Biocomput

Paziewska A, Wyrwicz LS, Bujnicki JM, Bomsztyk K, Ostrowski J

Cooperative binding of the hnRNP K three KH domains to mRNA targets.


Nes WD, Jayasimha P, Zhou W, Kanagasabai R, Jin C, Jaradat TT, Shaw RW, Bujnicki JM

Sterol methyltransferase: functional analysis of highly conserved residues by site-directed mutagenesis.


Maravić G, Bujnicki JM, Flögel M

Mutational analysis of basic residues in the N-terminus of the rRNA:m6A methyltransferase ErmC'

Folia Microbiol (Praha)

Koudan EV, Bujnicki JM, Gromova ES

Homology modeling of the CG-specific DNA methyltransferase SssI and its complexes with DNA and AdoHcy.

J Biomol Struct Dyn

Bujnicki JM, Oudjama Y, Roovers M, Owczarek S, Caillet J, Droogmans L

Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA.


Bujnicki JM, Feder M, Ayres CL, Redman KL

Sequence-structure-function studies of tRNA:m5C methyltransferase Trm4p and its relationship to DNA:m5C and RNA:m5U methyltransferases.

Nucleic Acids Res

Armengaud J, Urbonavicius J, Fernandez B, Chaussinand G, Bujnicki JM, Grosjean H

N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.

J Biol Chem

Koudan EV, Bujnicki JM, Gromova ES

Homology modeling of the CG-specific DNA methyltransferase SssI and its complexes with DNA and AdoHcy.

J Biomol Struct Dyn

Bujnicki JM, Oudjama Y, Roovers M, Owczarek S, Caillet J, Droogmans L

Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA.


Bujnicki JM, Feder M, Ayres CL, Redman KL

Sequence-structure-function studies of tRNA:m5C methyltransferase Trm4p and its relationship to DNA:m5C and RNA:m5U methyltransferases.

Nucleic Acids Res

Armengaud J, Urbonavicius J, Fernandez B, Chaussinand G, Bujnicki JM, Grosjean H

N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.

J Biol Chem

Mycko MP, Cwiklinska H, Szymanski J, Szymanska B, Kudla G, Kilianek L, Odyniec A, Brosnan CF, Selmaj KW

Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II.

J Immunol

Walerych D, Kudla G, Gutkowska M, Wawrzynow B, Muller L, King FW, Helwak A, Boros J, Zylicz A, Zylicz M

Hsp90 chaperones wild-type p53 tumor suppressor protein.

J Biol Chem

Jassem J, Jassem E, Jakóbkiewicz-Banecka J, Rzyman W, Badzio A, Dziadziuszko R, Kobierska-Gulida G, Szymanowska A, Skrzypski M, Zylicz M

P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma.


Dworakowska D, Jassem E, Jassem J, Peters B, Dziadziuszko R, Zylicz M, Jakóbkiewicz-Banecka J, Kobierska-Gulida G, Szymanowska A, Skokowski J, Roessner A, Schneider-Stock R

MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC).

Lung Cancer

Mycko MP, Cwiklinska H, Szymanski J, Szymanska B, Kudla G, Kilianek L, Odyniec A, Brosnan CF, Selmaj KW

Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II.

J Immunol

Kudla G, Helwak A, Lipinski L

Gene conversion and GC-content evolution in mammalian Hsp70.

Mol Biol Evol

Walerych D, Kudla G, Gutkowska M, Wawrzynow B, Muller L, King FW, Helwak A, Boros J, Zylicz A, Zylicz M

Hsp90 chaperones wild-type p53 tumor suppressor protein.

J Biol Chem

Müller L, Schaupp A, Walerych D, Wegele H, Buchner J

Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures.

J Biol Chem

Jassem J, Jassem E, Jakóbkiewicz-Banecka J, Rzyman W, Badzio A, Dziadziuszko R, Kobierska-Gulida G, Szymanowska A, Skrzypski M, Zylicz M

P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma.


Dworakowska D, Jassem E, Jassem J, Peters B, Dziadziuszko R, Zylicz M, Jakóbkiewicz-Banecka J, Kobierska-Gulida G, Szymanowska A, Skokowski J, Roessner A, Schneider-Stock R

MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC).

Lung Cancer


Pruszynski J, Gross R, Mossakowska M, Barcikowska M, Czyzewski K, Derejczyk J, Galus K, Grodzicki T, Jedrkiewicz H, Klich-Raczka A, Kupsc W, Luczywek E, Pfeffer A, Puzianowska-Kuznicka M, Sosnowski M, Styczynska M, Wasiak B, Wieczorowska-Tobis K, Zyczkows

Functioning of Polish centenarians


Wojda A, Witt M

Manifestations of ageing at the cytogenetic level

J Appl Genet

Wojda A, Wolnik-Brzozowska D, Lubka M, Mossakowska M, Witt M

The 102-year old woman with translocation (7;12) and infertility in anamnesis

J Appl Genet

Zyczkowska J, Klich-Raczka A, Wizner B, Mossakowska M, Wieczorowska-Tobis K, Grodzicki T

Hypertension and cognitive and functional performance in centenarians

New Medicine

Majka L, Goździk J, Witt M

Cystic fibrosis--a probable cause of Frédéric Chopin's suffering and death

J Appl Genet

Filipek S, Teller DC, Palczewski K, Stenkamp R

The crystallographic model of rhodopsin and its use in studies of other G protein-coupled receptors.

Annu Rev Biophys Biomol Struct

Fotiadis D, Liang Y, Filipek S, Saperstein DA, Engel A, Palczewski K

Atomic-force microscopy: Rhodopsin dimers in native disc membranes


Fritze O, Filipek S, Kuksa V, Palczewski K, Hofmann KP, Ernst OP

Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation.

Proc Natl Acad Sci U S A

Liang Y, Fotiadis D, Filipek S, Saperstein DA, Palczewski K, Engel A

Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes.

J Biol Chem

Liang Y, Fotiadis D, Filipek S, Saperstein DA, Palczewski K, Engel A

Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes

J Biol Chem

Maeda T, Van Hooser JP, Driessen CA, Filipek S, Janssen JJ, Palczewski K

Evaluation of the role of the retinal G protein-coupled receptor (RGR) in the vertebrate retina in vivo.

J Neurochem

Mirzadegan T, Benkö G, Filipek S, Palczewski K

Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin.


Noorwez SM, Kuksa V, Imanishi Y, Zhu L, Filipek S, Palczewski K, Kaushal S

Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosa.

J Biol Chem

Schadel SA, Heck M, Maretzki D, Filipek S, Teller DC, Palczewski K, Hofmann KP

Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin.

J Biol Chem

Nowotny M, Spiechowicz M, Jastrzebska B, Filipek A, Kitagawa K, Kuznicki J

Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins

J Biol Chem

Palczewska M, Groves P, Batta G, Heise B, Kuźnicki J

Calretinin and calbindin D28k have different domain organizations

Protein Sci

Pepłońska B, Zekanowski C, Religa D, Czyzewski K, Styczyńska M, Pfeffer A, Gabryelewicz T, Gołebiowski M, Luczywek E, Wasiak B, Barczak A, Chodakowska M, Barcikowska M, Kuźnicki J

Strong association between Saitohin gene polymorphism and tau haplotype in the Polish population

Neurosci Lett

Zekanowski C, Styczyńska M, Pepłońska B, Gabryelewicz T, Religa D, Ilkowski J, Kijanowska-Haładyna B, Kotapka-Minc S, Mikkelsen S, Pfeffer A, Barczak A, Łuczywek E, Wasiak B, Chodakowska-Zebrowska M, Gustaw K, Łaczkowski J, Sobów T, Kuźnicki J, Barcikowsk

Mutations in presenilin 1, presenilin 2 and amyloid precursor protein genes in patients with early-onset Alzheimer's disease in Poland

Exp Neurol

Zekanowski C, Pepłońska B, Styczyńska M, Gustaw K, Kuźnicki J, Barcikowska M

Mutation screening of the MAPT and STH genes in Polish patients with clinically diagnosed frontotemporal dementia

Dement Geriatr Cogn Disord

Zekanowski C, Przyluska-Fiszer A, Barcikowska M

Alzheimer's disease: between diagnostic, economy and ethic (in Polish)

Choroby otępienne. Teoria i praktyka

Tighe O, Dunican D, O'Neill C, Bertorelle G, Beattie D, Graham C, Zschocke J, Cali F, Romano V, Hrabincova E, Kozak L, Nechyporenko M, Livshits L, Guldberg P, Jurkowska M, Zekanowski C, Perez B, Desviat LR, Ugarte M, Kucinskas V, Knappskog P, Treacy E, N

Genetic diversity within the R408W phenylketonuria mutation lineages in Europe

Hum Mutat

Zekanowski C

The sun, the genome, the internet… eugenics?

Gemellological Rev

Zekanowski C

Molecular diagnostics of Alzheimer's disease (in Polish)

Medycyna ogólna

Dubin G, Krajewski M, Popowicz G, Stec-Niemczyk J, Bochtler M, Potempa J, Dubin A, Holak TA

A novel class of cysteine protease inhibitors: solution structure of staphostatin A from Staphylococcus aureus.


Filipek R, Rzychon M, Oleksy A, Gruca M, Dubin A, Potempa J, Bochtler M

The Staphostatin-staphopain complex: a forward binding inhibitor in complex with its target cysteine protease.

J Biol Chem

Rzychon M, Filipek R, Sabat A, Kosowska K, Dubin A, Potempa J, Bochtler M

Staphostatins resemble lipocalins, not cystatins in fold

Protein Sci

Scholz SR, Korn C, Bujnicki JM, Gimadutdinow O, Pingoud A, Meiss G

Experimental evidence for a beta beta alpha-Me-finger nuclease motif to represent the active site of the caspase-activated DNase.


Sasin JM, Kurowski MA, Bujnicki JM

STRUCLA: a WWW meta-server for protein structure comparison and evolutionary classification.


Pingoud V, Conzelmann C, Kinzebach S, Sudina A, Metelev V, Kubareva E, Bujnicki JM, Lurz R, Lüder G, Xu SY, Pingoud A

PspGI, a type II restriction endonuclease from the extreme thermophile Pyrococcus sp.: structural and functional studies to investigate an evolutionary relationship with several mesophilic restriction enzymes

J Mol Biol

Mouaikel J, Bujnicki JM, Tazi J, Bordonné R

Sequence-structure-function relationships of Tgs1, the yeast snRNA/snoRNA cap hypermethylase

Nucleic Acids Res

Maravić G, Feder M, Pongor S, Flögel M, Bujnicki JM

Mutational analysis defines the roles of conserved amino acid residues in the predicted catalytic pocket of the rRNA:m6A methyltransferase ErmC'

J Mol Biol

Maravić G, Bujnicki JM, Feder M, Pongor S, Flögel M

Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions

Nucleic Acids Res

Kurowski MA, Sasin JM, Feder M, Debski J, Bujnicki JM

Characterization of the cofactor-binding site in the SPOUT-fold methyltransferases by computational docking of S-adenosylmethionine to three crystal structures.

BMC Bioinformatics

Kurowski MA, Bujnicki JM

GeneSilico protein structure prediction meta-server.

Nucleic Acids Res

Kurowski MA, Bhagwat AS, Papaj G, Bujnicki JM

Phylogenomic identification of five new human homologs of the DNA repair enzyme AlkB.

BMC Genomics

Kosinski J, Cymerman IA, Feder M, Kurowski MA, Sasin JM, Bujnicki JM

A "FRankenstein's monster" approach to comparative modeling: merging the finest fragments of Fold-Recognition models and iterative model refinement aided by 3D structure evaluation


Gordon RK, Ginalski K, Rudnicki WR, Rychlewski L, Pankaskie MC, Bujnicki JM, Chiang PK

Anti-HIV-1 activity of 3-deaza-adenosine analogs. Inhibition of S-adenosylhomocysteine hydrolase and nucleotide congeners.

Eur J Biochem

Feder M, Pas J, Wyrwicz LS, Bujnicki JM

Molecular phylogenetics of the RrmJ/fibrillarin superfamily of ribose 2'-O-methyltransferases


Droogmans L, Roovers M, Bujnicki JM, Tricot C, Hartsch T, Stalon V, Grosjean H

Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures.

Nucleic Acids Res

De Bie LG, Roovers M, Oudjama Y, Wattiez R, Tricot C, Stalon V, Droogmans L, Bujnicki JM

The yggH gene of Escherichia coli encodes a tRNA (m7G46) methyltransferase.

J Bacteriol

Bujnicki JM, Prigge ST, Caridha D, Chiang PK

Structure, evolution, and inhibitor interaction of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.


Bujnicki JM, Albert MA, Nelson DJ, Thurlow DL

Fold recognition, homology modeling, docking simulations, kinetics analysis and mutagenesis of ATP/CTP:tRNA nucleotidyltransferase from Methanococcus jannaschii.


Bujnicki JM

Crystallographic and bioinformatic studies on restriction endonucleases: inference of evolutionary relationships in the "midnight zone" of homology

Curr Protein Pept Sci

Coker JA, Sheridan PP, Loveland-Curtze J, Gutshall KR, Auman AJ, Brenchley JE

Biochemical characterization of a beta-galactosidase with a low temperature optimum obtained from an Antarctic arthrobacter isolate.

J Bacteriol

Coker JA, Sheridan PP, Loveland-Curtze J, Gutshall KR, Auman AJ, Brenchley JE

Biochemical characterization of a beta-galactosidase with a low temperature optimum obtained from an Antarctic arthrobacter isolate.

J Bacteriol

Nowotny M, Spiechowicz M, Jastrzebska B, Filipek A, Kitagawa K, Kuznicki J

Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins

J Biol Chem.


Wieczorowska-Tobis K, Mossakowska M, Niemir Z, Breborowicz A, Oreopoulos DG

Discrepancies in creatinine clearance in centenarians when calculated by two different mathematical formulas

Nephrol Dial Transplant

Wieczorowska-Tobis K, Niemir Z, Mossakowska M, Klich-Raczka A, Zyczkowska J

Anemia in centenarians

J Am Geriatr Soc

Kuksa V, Bartl F, Maeda T, Jang GF, Ritter E, Heck M, Van Hooser JP, Liang Y, Filipek S, Gelb MH, Hofmann KP, Palczewski K

Biochemical and physiological properties of rhodopsin regenerated with 11-cis-6-ring- and 7-ring-retinals.

J Biol Chem

Billing-Marczak K, Buzanska L, Winsky L, Nowotny M, Rudka T, Isaacs K, Belin MF, Kuznicki J

AP2-like cis element is required for calretinin gene promoter activity in cells of neuronal phenotype differentiated from multipotent human cell line DEV

Biochim Biophys Acta

Filipek A, Jastrzebska B, Nowotny M, Kuznicki J

CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family

J Biol Chem

Filipek A, Jastrzebska B, Nowotny M, Kwiatkowska K, Hetman M, Surmacz L, Wyroba E,Kuznicki J

Ca2+-dependent translocation of the calcyclin-binding protein in neurons and neuroblastoma NB-2a cells

J Biol Chem

Cabalska B, Nowacka M, Nowaczewska I, Zekanowski C, Zorska K

Atypical PKU - treatment effectiveness

Medycyna Wieku Rozwojowego VI

Zekanowski C, Gizewska M, Nowacka M, Cabalska B

Novel PKU treatment methods

Medycyna Wieku Rozwojowego

Zekanowski C

Genetic aspects of Alzheimer’s disease

Medycyna Ogólna

Ramachandran R, Hartmann C, Song HK, Huber R, Bochtler M

Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY)

Proc Natl Acad Sci U S A

Zhang P, Nicholson DE, Bujnicki JM, Su X, Brendle JJ, Ferdig M, Kyle DE, Milhous WK, Chiang PK

Angiogenesis inhibitors specific for methionine aminopeptidase 2 as drugs for malaria and leishmaniasis

J Biomed Sci

Xu Y, Keene DR, Bujnicki JM, Höök M, Lukomski S

Streptococcal Scl1 and Scl2 proteins form collagen-like triple helices.

J Biol Chem

Pintard L, Lecointe F, Bujnicki JM, Bonnerot C, Grosjean H, Lapeyre B

Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop


Pintard L, Bujnicki JM, Lapeyre B, Bonnerot C

MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase


Pingoud V, Kubareva E, Stengel G, Friedhoff P, Bujnicki JM, Urbanke C, Sudina A, Pingoud A

Evolutionary relationship between different subgroups of restriction endonucleases.

J Biol Chem

Godlewska R, Bujnicki JM, Ostrowski J, Jagusztyn-Krynicka EK

The hppA gene of Helicobacter pylori encodes the class C acid phosphatase precursor


Bujnicki J, Rychlewski L, Fischer D

Fold-recognition detects an error in the Protein Data Bank


Bujnicki JM, Rychlewski L

In silico identification, structure prediction and phylogenetic analysis of the 2'-O-ribose (cap 1) methyltransferase domain in the large structural protein of ssRNA negative-strand viruses

Protein Eng

Bujnicki JM, Rychlewski L

RNA:(guanine-N2) methyltransferases RsmC/RsmD and their homologs revisited--bioinformatic analysis and prediction of the active site based on the uncharacterized Mj0882 protein structure

BMC Bioinformatics

Bujnicki JM, Rychlewski L

Fold-recognition analysis predicts that the Tag protein family shares a common domain with the helix-hairpin-helix DNA glycosylases

DNA Repair (Amst)

Bujnicki JM, Leach RA, Debski J, Rychlewski L

Bioinformatic analyses of the tRNA: (guanine 26, N2,N2)-dimethyltransferase (Trm1) family

J Mol Microbiol Biotechnol

Bujnicki JM, Feder M, Rychlewski L, Fischer D

Errors in the D. radiodurans large ribosomal subunit structure detected by protein fold-recognition and structure validation tools


Bujnicki JM, Feder M, Radlinska M, Blumenthal RM

Structure prediction and phylogenetic analysis of a functionally diverse family of proteins homologous to the MT-A70 subunit of the human mRNA:m(6)A methyltransferase

J Mol Evol

Bujnicki JM, Blumenthal RM, Rychlewski L

Sequence analysis and structure prediction of 23S rRNA:m1G methyltransferases reveals a conserved core augmented with a putative Zn-binding domain in the N-terminus and family-specific elaborations in the C-terminus

J Mol Microbiol Biotechnol

Bujnicki JM

Sequence permutations in the molecular evolution of DNA methyltransferases

BMC Evol Biol

Filipek A, Jastrzebska B, Nowotny M, Kwiatkowska K, Hetman M, Surmacz L, Wyroba E, Kuznicki J

Ca2+-dependent translocation of the calcyclin-binding protein in neurons and neuroblastoma NB-2a cells.

J Biol Chem

Filipek A, Jastrzebska B, Nowotny M, Kuznicki J

CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family

J Biol Chem

Billing-Marczak K, Buzanska L, Winsky L, Nowotny M, Rudka T, Isaacs K, Belin MF, Kuznicki J.

AP2-like cis element is required for calretinin gene promoter activity in cells of neuronal phenotype differentiated from multipotent human cell line DEV.

Biochim Biophys Acta


Wieczorowska-Tobis K, Mossakowska M, Niemir Z, Breborowicz A, Oreopoulos DG

Plasma creatine and sodium abnormalities in Polish centenarians

Ann Acad Med Gedan

Palczewska M, Groves P, Ambrus A, Kaleta A, Kövér KE, Batta G, Kuźnicki J.

Structural and biochemical characterization of neuronal calretinin domain I-II (residues 1-100). Comparison to homologous calbindin D28k domain I-II (residues 1-93)

Eur J Biochem.

Radlinska M, Bujnicki JM

Site-directed mutagenesis defines the catalytic aspartate in the active site of the atypical DNA: m4C methyltransferase M.NgoMXV

Acta Microbiol Pol

Radlinska M, Bujnicki JM

Cloning of enterohemorrhagic Escherichia coli phage VT-2 dam methyltransferase

Acta Microbiol Pol

Lundström J, Rychlewski L, Bujnicki J, Elofsson A

Pcons: a neural-network-based consensus predictor that improves fold recognition

Protein Sci

Bujnicki JM, Rychlewski L

The herpesvirus alkaline exonuclease belongs to the restriction endonuclease PD-(D/E)XK superfamily: insight from molecular modeling and phylogenetic analysis.

Virus Genes

Bujnicki JM, Rychlewski L

Grouping together highly diverged PD-(D/E)XK nucleases and identification of novel superfamily members using structure-guided alignment of sequence profiles.

J Mol Microbiol Biotechnol

Bujnicki JM, Rychlewski L

Reassignment of specificities of two cap methyltransferase domains in the reovirus lambda 2 protein

Genome Biol

Bujnicki JM, Rychlewski L

Unusual evolutionary history of the tRNA splicing endonuclease EndA: relationship to the LAGLIDADG and PD-(D/E)XK deoxyribonucleases.

Protein Sci

Bujnicki JM, Rychlewski L

Identification of a PD-(D/E)XK-like domain with a novel configuration of the endonuclease active site in the methyl-directed restriction enzyme Mrr and its homologs


Bujnicki JM, Rychlewski L

Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases

Acta Microbiol Pol

Bujnicki JM, Rotkiewicz P, Kolinski A, Rychlewski L

Three-dimensional modeling of the I-TevI homing endonuclease catalytic domain, a GIY-YIG superfamily member, using NMR restraints and Monte Carlo dynamics.

Protein Eng

Bujnicki JM, Radlinska M, Zaleski P, Piekarowicz A

Cloning of the Haemophilus influenzae Dam methyltransferase and analysis of its relationship to the Dam methyltransferase encoded by the HP1 phage

Acta Biochim Pol

Bujnicki JM, Radlinska M, Rychlewski L

Polyphyletic evolution of type II restriction enzymes revisited: two independent sources of second-hand folds revealed

Trends Biochem Sci

Bujnicki JM, Radlinska M

Cloning and characterization of M.LmoA118I, a novel DNA:m4C methyltransferase from the Listeria monocytogenes phage A118, a close homolog of M.NgoMXV

Acta Microbiol Pol

Bujnicki JM, Feder M, Radlinska M, Rychlewski L

mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships

BMC Bioinformatics

Bujnicki JM, Elofsson A, Fischer D, Rychlewski L

LiveBench-2: large-scale automated evaluation of protein structure prediction servers.


Bujnicki JM, Elofsson A, Fischer D, Rychlewski L

LiveBench-1: continuous benchmarking of protein structure prediction servers

Protein Sci

Bujnicki JM, Elofsson A, Fischer D, Rychlewski L

Structure prediction meta server


Bujnicki JM

A model of structure and action of Sau3AI restriction endonuclease that comprises two MutH-like endonuclease domains within a single polypeptide.

Acta Microbiol Pol

Bujnicki JM

Understanding the evolution of restriction-modification systems: clues from sequence and structure comparisons.

Acta Biochim Pol

Bujnicki JM

In silico analysis of the tRNA:m1A58 methyltransferase family: homology-based fold prediction and identification of new members from Eubacteria and Archaea


Kaczanowski R, Trzeciak L, Kucharczyk K

Multitemperature single-strand conformation polymorphism.


Zylicz M, Wawrzynow A

Insights into the function of Hsp70 chaperones.


Zylicz M, King FW, Wawrzynow A

Hsp70 interactions with the p53 tumour suppressor protein


King FW, Wawrzynow A, Höhfeld J, Zylicz M

Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.


Jassem E, Nikliński J, Rosell R, Niklińska W, Jakóbkiewicz J, Monzo M, Chyczewski L, Kobierska G, Skokowski J, Zylicz M, Jassem J

Types and localisation of p53 gene mutations: a report on 332 non-small cell lung cancer patients.

Lung Cancer

Genevaux P, Wawrzynow A, Zylicz M, Georgopoulos C, Kelley WL

DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction.

J Biol Chem

Banecki B, Wawrzynow A, Puzewicz J, Georgopoulos C, Zylicz M

Structure-function analysis of the zinc-binding region of the Clpx molecular chaperone.

J Biol Chem

Kaczanowski R, Trzeciak L, Kucharczyk K

Multitemperature single-strand conformation polymorphism.


Zylicz M, Wawrzynow A

Insights into the function of Hsp70 chaperones.


Zylicz M, King FW, Wawrzynow A

Hsp70 interactions with the p53 tumour suppressor protein


King FW, Wawrzynow A, Höhfeld J, Zylicz M

Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.


Genevaux P, Wawrzynow A, Zylicz M, Georgopoulos C, Kelley WL

DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction.

J Biol Chem

Banecki B, Wawrzynow A, Puzewicz J, Georgopoulos C, Zylicz M

Structure-function analysis of the zinc-binding region of the Clpx molecular chaperone.

J Biol Chem


Nowotny M, Bhattacharya S, Filipek A, Krezel AM, Chazin W, Kuznicki J.

Characterization of the interaction of calcyclin (S100A6) and calcyclin-binding protein.

J Biol Chem.

Jastrzebska B, Filipek A, Nowicka D, Kaczmarek L, Kuznicki J.

Calcyclin (S100A6) binding protein (CacyBP) is highly expressed in brain neurons.

J Histochem Cytochem.

Leśniak W, Jezierska A, Kuźnicki J.

Upstream stimulatory factor is involved in the regulation of the human calcyclin (S100A6) gene.

Biochim Biophys Acta.

Leśniak W, Swart GW, Bloemers HP, Kuźnicki J.

Regulation of cell specific expression of calcyclin (S100A6) in nerve cells and other tissues.

Acta Neurobiol Exp (Wars).

Zekanowski C

Cloning - the crossroads of biology and culture

Gemellological Review

Mossakowska M, Puzianowska-Kuznicka M, Barcikowska M, Chiron-Jouan S, Czyzewski K, Derejczyk J, Franceschi C, Gabryelewicz T, Galus K, Grodzicki T, Gross R, Klich-Raczka A, Luczywek E, Passeri G, Pfeffer A, Pruszynski J, Radziszewska E, Sikora E, Sosnowski M, Styczynska M, Wasiak B, Wieczorowska-Tobis K, Zyczkowska J, Kuznicki J

Polish Centenarians Program “PolStu99” – search for longevity promoting factors (in Polish)


Bujnicki JM, Rychlewski L

Prediction of a common fold for all four subunits of the yeast tRNA splicing endonuclease: implications for the evolution of the EndA/Sen family.


Bujnicki JM, Rychlewski L

Prediction of a novel RNA 2'-O-ribose methyltransferase subfamily encoded by the Escherichia coli YgdE open reading frame and its orthologs

Acta Microbiol Pol

Bujnicki JM, Radlinska M, Rychlewski L

Atomic model of the 5-methylcytosine-specific restriction enzyme McrA reveals an atypical zinc finger and structural similarity to betabetaalphaMe endonucleases

Mol Microbiol

Bujnicki JM

Sequence, structural, and evolutionary analysis of prokaryotic ribosomal protein L11 methyltransferases.

Acta Microbiol Pol

Bujnicki JM

Phylogenomic analysis of 16S rRNA:(guanine-N2) methyltransferases suggests new family members and reveals highly conserved motifs and a domain structure similar to other nucleic acid amino-methyltransferases.