Postdoctoral Researcher positions in Laboratory of RNA-Protein Interactions - Dioscuri Centre

Laboratory of RNA-Protein Interactions - Dioscuri Centre https://shorturl.at/AHPW3 at the International Institute of Molecular and Cell Biology (IIMCB), Warsaw, headed by prof. dr hab. Gracjan Michlewski, is looking for a Postdoctoral Researcher.

You will join the project entitled You will join the project entitled “Biological control and pharmacological regulation of RNAs implicated in aetiology of Parkinson’s disease” carried out from 2024 to 2028 as the OPUS grant (UMO-2023/49/B/NZ1/02456) of the National Science Centre, Poland.

The primary aim of this project is to analyse and modulate the interactions between HuR (ELAVL1) and RNA, which play a crucial role in regulating the expression of alpha-Syn, a key protein linked to Parkinson's disease (PD) pathology. To achieve this objective, we are assembling a diverse team of researchers and collaborators who will utilize various human cells and well as novel C. elegans PD model.

As a Postdoctoral Researcher, you will be involved in characterizing the biological control and pharmacological regulation of HuR-RNA interactions in human neuronal cells, as well as in a C. elegans PD model incorporating a human alpha-Syn transgene. Additionally, you will share responsibility for assessing selected compounds against HuR and C. elegans exc-7 (HuR ortholog). Ultimately, these investigations will help to uncover novel pathways and therapeutic approaches in PD and other diseases linked to abnormal gene expression and RNA metabolism.

The ideal candidate should be able to pursue challenging tasks and achieve objectives and collaborate with other researchers. Candidates will be selected in an open competition, according to the procedure complying with the rules of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers as a part of HR Excellence in Research strategy https://shorturl.at/fvBO5

Requirements:

1. Holds a doctoral degree in biology, biochemistry, pharmacology, medicine or related field
2. Fulfils the formal criteria for the competition https://shorturl.at/tGPU6 in particular included on the pages 61 – 62
3. Possesses advanced knowledge in molecular and cell biology. While familiarity with elegans or iPSCs culture is not mandatory, it would be a significant advantage.
4. Demonstrates expertise and strong interest in cell biology, exhibits motivation for experimental work, and displays a genuine passion for science.
5. Has extensive laboratory experience.
6. Has well-documented research achievements, including publication record and active participation in conference presentations.
7. Exhibits a willingness to acquire new skills and embrace challenges, demonstrating the ability to work independently and in a team.
8. Possesses excellent English language communication and writing skills.
9. Mobility and prior research experience abroad would be advantageous but are not obligatory.

We offer:

• Full employment contract for one year, with the possibility of extension for the duration of the project
• The basic monthly gross salary starts at 8 700 PLN (the final monthly gross salary will be calculated individually during employment, considering the skills or length of experience). Additional bonuses such as Christmas bonus may supplement this salary.
• Position with 100% focus on research (no teaching obligations)
• Benefits including reduced-rate for an individual medical care package and membership
  in MultiSport programme
• Full technical, administrative and organizational support from professional English-speaking personnel
• Participation in courses, scientific training, support from peers, and academic mentoring

Deadline for applications is January 5th, 2024 (but can be prolonged if no suitable candidates are found). Job starting date is March 1, 2024, or later.

How to apply:

• Apply now to This email address is being protected from spambots. You need JavaScript enabled to view it.
• In the subject include "Postdoc_OPUS_GM" and your first and last name.
• Your application must be submitted in English and should contain a CV, a motivation letter, a description of your key achievements, and contact details at least two potential referees, including one of your supervisors
• Please include the following statement in your CV: “I hereby agree to the processing of my personal data, included in the application documents by the International Institute of Molecular and Cell Biology in Warsaw, 4 Księcia Trojdena Street, 02-109 Warsaw, for the purpose of carrying out the current recruitment process.” Your personal data will be processed for the purpose of the recruitment procedure by the International Institute of Molecular and Cell Biology in Warsaw.
  Full information is available under the link https://bit.ly/3UFWpY2
• The competition may be extended until a suitable candidate who fulfils all requirements is found.

Chcielibyśmy poinformować, że konkurs na stanowisko Postdoctroral Researcher został rozstrzygnięty. Wybraną kandydatką jest Justyna Sobich./We would like to inform that the competition for Postdoctoral Researcher has been closed. The selected candidate is Justyna Sobich.