All publications
2025
The cross-sectional relationship of physical frailty and cognitive impairment in older Poles: analysis of the PolSenior2 data.
Skalska A, Piotrowicz K, Kujawska-Danecka H, Jagiełło K, Rączka AK, Mossakowska M, Zdrojewski T, Grodzicki T, Gąsowski J.
Eur Geriatr Med. 2025
From discovery to potential application: engineering a novel M23 peptidase to combat Listeria monocytogenes.
Kaus-Drobek M, Nowacka M, Gewartowska M, Korzeniowska Nee Wiweger M, Jensen MR, Møretrø T, Heir E, Nowak E, Sabała I.
Sci Rep. 2025
Message hidden in α-helices-toward a better understanding of plant ABCG transporters' multispecificity.
Biała-Leonhard W, Bigos A, Brezovsky J, Jasiński M.
Plant Physiol. 2025
Pentraxin-3 and C-reactive protein plasma levels predict survival in older adults with or without metabolic syndrome – results of the PolSenior2 substudy.
Owczarek AJ, Ochman A, Chudek A, Mossakowska M, Puzianowska-Kuźnicka M, Kujawska-Danecka H, Zdrojewski T, Więcek A, Chudek J, Olszanecka-Glinianowicz M.
Immun Ageing. 2025
Activity and structure of human (d)CTP deaminase CDADC1.
Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M.
Proc Natl Acad Sci U S A. 2025
Determining the effects of pseudouridine incorporation on human tRNAs.
Biela AD, Nowak JS, Biela AP, Mukherjee S, Moafinejad SN, Maiti S, Chramiec-Głąbik A, Mehta R, Jeżowski J, Dobosz D, Dahate P, Arluison V, Wien F, Indyka P, Rawski M, Bujnicki JM, Lin TY, Glatt S.
EMBO J. 2025
Tailoring Alkyl Side Chains of Ionizable Amino-Polyesters for Enhanced In Vivo mRNA Delivery.
López Espinar A, Mulder LM, Elkhashab M, Khan Z, Czarnocki-Cieciura M, Aburto MR, Vucen S, Kowalski PS.
ACS Appl Bio Mater. 2025
Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines.
Krawczyk PS, Mazur M, Orzeł W, Gewartowska O, Jeleń S, Antczak W, Kasztelan K, Brouze A, Matylla-Kulińska K, Gumińska N, Tarkowski B, Owczarek EP, Affek K, Turowski P, Tudek A, Sroka M, Śpiewla T, Kusio-Kobiałka M, Wesołowska A, Nowis D, Golab J, Kowalska J, Jemielity J, Dziembowski A, Mroczek S.
Nature. 2025
Equivalent outcomes of human oocytes after vitrification or slow freezing with a modified rehydration protocol.
Papis K, Hardej K, Stachowiak E, Żyżyńska-Galeńska K, Lewandowski P, Kozioł K.
Reprod Biol Endocrinol. 2025
Structural and biochemical characterization of the 3'-5' tRNA splicing ligases.
Chamera S, Zajko W, Czarnocki-Cieciura M, Jaciuk M, Koziej Ł, Nowak J, Wycisk K, Sroka M, Chramiec-Głąbik A, Śmietański M, Gołębiowski F, Warmiński M, Jemielity J, Glatt S, Nowotny M.
J Biol Chem. 2025
Protein-RNA Docking Benchmark v3.0 Integrated With Binding Affinity.
Kant S, Nithin C, Mukherjee S, Maity A, Bahadur RP.
Proteins. 2025
Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin.
Domagala J, Grzywa TM, Baranowska I, Justyniarska M, Tannir R, Graczyk-Jarzynka A, Kusowska A, Lecka M, Poreba M, Fidyt K, Marhelava K, Pilch Z, Picard LK, Wegierski T, Jastrzebski K, Krawczyk M, Klopotowska M, Granica M, Urlaub D, Hajduk S, Neeser A, Moros S, Kozlowski P, Bobrowicz M, Miaczynska M, Ma L, Watzl C, Winiarska M.
Cancer Res. 2025
Protocol for the visualization of pRps6-positive cells in larval zebrafish brains using whole-mount immunofluorescence and light-sheet microscopy.
Doszyn O, Dulski T, Zmorzynska J.
STAR Protoc. 2025
A new insight into the fabrication of colloidal isotropic ZnO nanocrystals by an organometallic approach.
Wojewódzka A, Wolska-Pietkiewicz M, Szczepanowski RH, Jędrzejewska M, Zelga K, Lewiński J.
Nanoscale Adv. 2025
Exploring the impact of MDMA and oxytocin ligands on anxiety and social responses: A comprehensive behavioural and molecular study in the zebrafish model.
Maciag M, Doszyn O, Wnorowski A, Zmorzynska J, Budzynska B.
J Psychopharmacol. 2025
Direct profiling of non-adenosines in poly(A) tails of endogenous and therapeutic mRNAs with Ninetails.
Gumińska N, Matylla-Kulińska K, Krawczyk PS, Maj M, Orzeł W, Mackiewicz Z, Brouze A, Mroczek S, Dziembowski A.
Nat Commun. 2025
Terminal nucleotidyltransferase Tent2 microRNA A-tailing enzyme regulates excitatory/inhibitory balance in the hippocampus.
Wardaszka-Pianka P, Kuzniewska B, Guminska N, Hojka-Osinska A, Puchalska M, Milek J, Stawikowska A, Krawczyk P, Pauzin FP, Wojtowicz T, Radwanska K, Bramham CR, Dziembowski A, Dziembowska M.
RNA. 2025
Pentraxin-3 as a poor marker of fibrosis in metabolic dysfunction-associated steatotic liver disease among older adults: findings from the PolSenior2 substudy.
Owczarek AJ, Musialik J, Stefański A, Mossakowska M, Zięba K, Więcek A, Chudek J, Olszanecka-Glinianowicz M.
Front Med (Lausanne). 2025
Subclinical Thyroid Dysfunction and Mortality in an Older, Community-Dwelling Population-Results of the PolSenior Study.
Kocełak P, Owczarek AJ, Mossakowska M, Puzianowska-Kuźnicka M, Bolanowski M, Olszanecka-Glinianowicz M, Chudek J.
Clin Endocrinol (Oxf). 2025
Tmbim5 loss causes muscle atrophy in zebrafish without exacerbating mcu or slc8b1 knockout phenotypes.
Wasilewska I, Majewski Ł, Adamek-Urbańska D, Baranykova S, Macias M, Szybińska A, Methner A.
bioRxiv. 2025
p70S6 kinase-dependent phosphorylation of the μ2 subunit of the AP2 adaptor complex is needed for clathrin-mediated endocytosis.
Tempes A, Brzozowska A, Węgierski T, Olek K, Jastrzębski K, Liszewska E, Misztal K, Machnicka K, Macias M, Szybińska A, Sitkiewicz E, Gozdz A, Wróbel AG, Miaczynska M, Pokrzywa W, Jaworski J, Malik AR.
bioRxiv. 2025
Evaluating changes in dental status among Polish older adults over a decade: A comparative analysis of PolSenior (2009) and PolSenior2 (2019) surveys.
Dąbrowski W, Jagiełło K, Mossakowska M, Suligowska K, Zdrojewski TR, Chudek J, Górska R.
Dent Med Probl. 2025
DIS3L, cytoplasmic exosome catalytic subunit, is essential for development but not cell viability in mice.
Brouze M, Szpila M, Czerwińska AM, Antczak W, Mroczek S, Kuliński T, Hojka-Osińska AM, Cysewski D, Gewartowska O, Adamska D, Gruchota J, Borsuk E, Dziembowski A.
RNA. 2025
DesiRNA: structure-based design of RNA sequences with a replica exchange Monte Carlo approach.
Wirecki TK, Lach G, Badepally NG, Moafinejad SN, Jaryani F, Klaudel G, Nec K, Baulin EF, Bujnicki JM.
Nucleic Acids Res. 2025
Protocol for the preparation of zebrafish whole heart cell suspension for single-cell analyses.
Abu Nahia K, Winata CL.
STAR Protoc. 2025
CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3.
Kaushik V, Gessa L, Kumar N, Pinkas M, Czarnocki-Cieciura M, Palczewski K, Nováček J, Fernandes H.
Open Biol. 2025
Computational analysis of congenital heart disease associated SNPs: unveiling their impact on the gene regulatory system.
Vashisht S, Parisi C, Winata CL.
BMC Genomics. 2025
Anti-HBs Positivity Related to Past HBV Infection and Vaccination in Older Adults in Polish Population-Cohort-Based Study.
Zięba K, Jagiełło K, Musialik J, Wierucki Ł, Hajduk A, Mossakowska M, Chudek J.
Vaccines (Basel). 2025
Single-cell and spatial transcriptomics illuminate bat immunity and barrier tissue evolution.
Levinger R, Tussia-Cohen D, Friedman S, Lender Y, Nissan Y, Fraimovitch E, Gavriel Y, Tearle J, Kolodziejczyk AA, Moon KM, Gomes T, Kunowska N, Weinberg M, Donati G, Foster LJ, James KR, Yovel Y, Hagai T.
Mol Biol Evol. 2025
Effects of genetic ablation and pharmacological inhibition of HuR on gene expression, iron metabolism, and hormone levels.
Idlin N, Krishnamoorthy S, Wolczyk M, Fakhri M, Lechowski M, Stec N, Milek J, Mandal PK, Cendrowski J, Spanos C, Dziembowska M, Mleczko-Sanecka K, Rappsilber J, Michlewski G.
BMC Biol. 2025
A novel MAPK1 variant in a family with complex psychiatric and neurodegenerative clinical phenotype.
Dubey AA, Rydzanicz M, Barczak A, Szulc NA, Surpeta B, Kuzniewska B, Gaweda-Walerych K, Wężyk M, Berdyński M, Fichna JP, Kostrzewa G, Gasperowicz P, Stępniak I, Szymańska K, Szczałuba K, Brezovsky J, Dziembowska M, Pokrzywa W, Ploski R.
Research Square. 2025
Health status correlates of malnutrition diagnosed based on the GLIM criteria in older Polish adults-Results of the PolSenior 2 study.
Kaluźniak-Szymanowska A, Deskur-Śmielecka E, Krzymińska-Siemaszko R, Styszyński A, Tobis S, Lewandowicz M, Chudek J, Kostka T, Mossakowska M, Piotrowicz K, Kujawska-Danecka H, Wieczorowska-Tobis K.
PLoS One. 2025
Comprehensive analysis of poly(A) tails in mouse testes and ovaries using Nanopore Direct RNA Sequencing.
Czarnocka-Cieciura A, Brouze M, Gumińska N, Mroczek S, Gewartowska O, Krawczyk PS, Dziembowski A.
Sci Data. 2025
Protocol for microinjection of rapamycin into the zebrafish habenula.
Doszyn O, Dulski T, Zmorzynska J.
STAR Protoc. 2025
DEGRADATOR: A Gaming Expedition Into Targeted Protein Degradation Therapies.
Szulc NA, Olchowik A, Jaszczak P, Janiak B, Cup M, Tomaszewski J, Pokrzywa W.
J Chem Educ. 2025
5′ terminal nucleotide determines the immunogenicity of IVT RNAs.
Wolczyk M, Szymanski J, Trus I, Naz Z, Tame T, Bolembach A, Choudhury NR, Kasztelan K, Rappsilber J, Dziembowski A, Michlewski G.
Nucleic Acids Res. 2025
RNA-Puzzles Round V: blind predictions of 23 RNA structures.
Bu F, Adam Y, Adamiak RW, Antczak M, de Aquino BRH, Badepally NG, Batey RT, Baulin EF, Boinski P, Boniecki MJ, Bujnicki JM, Carpenter KA, Chacon J, Chen SJ, Chiu W, Cordero P, Das NK, Das R, Dawson WK, DiMaio F, Ding F, Dock-Bregeon AC, Dokholyan NV, Dror RO, Dunin-Horkawicz S, Eismann S, Ennifar E, Esmaeeli R, Farsani MA, Ferré-D'Amaré AR, Geniesse C, Ghanim GE, Guzman HV, Hood IV, Huang L, Jain DS, Jaryani F, Jin L, Joshi A, Karelina M, Kieft JS, Kladwang W, Kmiecik S, Koirala D, Kollmann M, Kretsch RC, Kurciński M, Li J, Li S, Magnus M, Masquida B, Moafinejad SN, Mondal A, Mukherjee S, Nguyen THD, Nikolaev G, Nithin C, Nye G, Pandaranadar Jeyeram IPN, Perez A, Pham P, Piccirilli JA, Pilla SP, Pluta R, Poblete S, Ponce-Salvatierra A, Popenda M, Popenda L, Pucci F, Rangan R, Ray A, Ren A, Sarzynska J, Sha CM, Stefaniak F, Su Z, Suddala KC, Szachniuk M, Townshend R, Trachman RJ 3rd, Wang J, Wang W, Watkins A, Wirecki TK, Xiao Y, Xiong P, Xiong Y, Yang J, Yesselman JD, Zhang J, Zhang Y, Zhang Z, Zhou Y, Zok T, Zhang D, Zhang S, Żyła A, Westhof E, Miao Z.
Nat Methods. 2025
Data storage based on the absence of nucleotides using a bacteriophage abortive infection system reverse transcriptase.
Bajc G, Pavlin A, Figiel M, Zajko W, Nowotny M, Butala M.
Lab Chip. 2025
Zebrafish in-vivo study reveals deleterious activity of human TBC1D24 genetic variants linked with autosomal dominant hearing loss.
Sarosiak A, Jędrychowska J, Oziębło D, Gan NS, Bałdyga N, Leja ML, Węgierski T, Cruz IA, Raible DW, Skarżyński H, Tylzanowski P, Korzh V, Ołdak M.
Biochim Biophys Acta Mol Basis Dis. 2025
CD71+ erythroid cells promote multiple myeloma progression and impair anti-bacterial immune response.
Czubak K, Grzywa TM, Sidor-Dzitkowska K, Pilch Z, Bielak K, Hoser G, Gewartowska O, Malecka-Gieldowska M, Barankiewicz J, Garbicz F, Ciepiela O, Juszczynski P, Owczarek A, Wegrzynowicz M, Skirecki T, Golab J, Nowis D.
Br J Haematol. 2025
Sci-ModoM: a quantitative database of transcriptome-wide high-throughput RNA modification sites.
Boileau E, Wilhelmi H, Busch A, Cappannini A, Hildebrand A, Bujnicki JM, Dieterich C.
Nucleic Acids Res . 2025
Zygotic activin a is dispensable for the mouse preimplantation embryo development and for the derivation and pluripotency of embryonic stem cells.
Winek E, Wolińska-Nizioł L, Szczepańska K, Szpakowska A, Gewartowska O, Wysocka I, Grzesiak M, Suwińska A.
Biol Reprod. 2025
How the technologies behind self-driving cars, social networks, ChatGPT, and DALL-E2 are changing structural biology.
Bochtler M.
Bioessays. 2025
NAIRDB: a database of Fourier transform infrared (FTIR) data for nucleic acids.
Balduzzi E, Geinguenaud F, Sordyl D, Maiti S, Farsani MA, Nikolaev G, Arluison V, Bujnicki JM.
Nucleic Acids Res. 2025
Ecological interactions in glacier environments: a review of studies on a model Alpine glacier.
Crosta A, Valle B, Caccianiga M, Gobbi M, Ficetola FG, Pittino F, Franzetti A, Azzoni RS, Lencioni V, Senese A, Corlatti L, Buda J, Poniecka E, Novotná Jaroměřská T, Zawierucha K, Ambrosini R.
Biol Rev. 2025
Autophagy at the postsynapse begins with Rab11 and does not end with dendritic spine pruning.
Janusz-Kaminska A, Jaworski J.
Autophagy Reports. 2025
Water Migration through Enzyme Tunnels Is Sensitive to the Choice of Explicit Water Model.
Thirunavukarasu AS, Szleper K, Tanriver G, Marchlewski I, Mitusinska K, Gora A, Brezovsky J.
J Chem Inf Model. 2025
2024
Factors Affecting Activity Patterns of the Whiskered Bat Myotis mystacinus (Kuhl, 1817) (Chiroptera: Vespertilionidae) in the Western Carpathians, Poland
Kurek K, Jędzrzejewsja B, Gewartowska O, Tołkacz K, Mysłajek RW.
Acta Zool Bulg. 2024
Role of Non-Canonical Stacking Interactions of Heterocyclic RNA Bases in Ribosome Function.
Metelev VG, Baulin EF, Bogdanov AA.
Biochemistry (Mosc). 2024
Prevalence of hypercholesterolemia in the elderly and very elderly members of the Polish population: results of a national cross‑sectional representative survey.
Chlebus K, Zdrojewski T, Jagiełło K, Mossakowska M, Chudek J, Więcek A, Grodzicki T.
Pol Arch Intern Med. 2024
Impact of water models on the structure and dynamics of enzyme tunnels.
Sethi A, Agrawal N, Brezovsky J.
Comput Struct Biotechnol J. 2024
Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants.
NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M.
Lancet. 2024
Proteomic Analyses Reveal the Role of Alpha-2-Macroglobulin in Canine Osteosarcoma Cell Migration.
Wilk SS, Michalak K, Owczarek EP, Winiarczyk S, Zabielska-Koczywąs KA.
Int J Mol Sci. 2024
NFκB and JNK pathways mediate metabolic adaptation upon ESCRT‑I deficiency.
Cendrowski J, Wrobel M, Mazur M, Jary B, Maurya R, Wang S, Korostynski M, Dziewulska A, Rohm M, Kuropka P, Pudelko‑Malik N, Mlynarz P, Dobrzyn A, Zeigerer A, Miaczynska M.
Cell Mol Life Sci. 2024
ATPase Valosin-Containing Protein (VCP) Is Involved During the Replication and Egress of Sialodacryoadenitis Virus (SDAV) in Neurons.
Bartak M, Krahel WD, Chodkowski M, Grel H, Walczak J, Pallepati A, Komorowski M, Cymerys J.
Int J Mol Sci. 2024
Endogenous ZAP is associated with altered Zika virus infection phenotype.
Le NPK, Singh PP, Sabir AJ, Trus I, Karniychuk U.
Virol J. 2024
Generation of four human induced pluripotent stem cell lines derived from patients with MPAN, subtype of NBIA, carrying the c.204_214del11 mutation in the C19orf12 gene.
Krogulec E, Dobosz AM, Liszewska E, Majchrowicz L, Dobrzyń A.
Stem Cell Res. 2024
Cryo-EM structure of raiA ncRNA from Clostridium reveals a new RNA 3D fold.
Goud Badepally N, Rocha de Moura T, Purta E, Baulin EF, Bujnicki JM.
J Mol Biol. 2024
The three YTHDF paralogs and VIRMA are strong cross-histotype tumor driver candidates among m6A core genes.
Destefanis E, Sighel D, Dalfovo D, Gilmozzi R, Broso F, Cappannini A, Bujnicki JM, Romanel A, Dassi E, Quattrone A.
NAR Cancer. 2024
Loss of Stim2 in zebrafish induces glaucoma-like phenotype.
Baranykova S, Gupta RK, Kajdasz A, Wasilewska I, Macias M, Szybinska A, Węgierski T, Nahia KA, Mondal SS, Winata CL, Kuźnicki J, Majewski L.
Sci Rep. 2024
The neuroprotective effect of short-chain fatty acids against hypoxia-reperfusion injury.
Harijan AK, Kalaiarasan R, Ghosh AK, Jain RP, Bera AK.
Mol Cell Neurosci. 2024
Modeling of mRNA deadenylation rates reveal a complex relationship between mRNA deadenylation and decay.
Czarnocka-Cieciura A, Poznański J, Turtola M, Tomecki R, Krawczyk PS, Mroczek S, Orzeł W, Saha U, Jensen TH, Dziembowski A, Tudek A.
EMBO J. 2024
HSP70 inhibits CHIP E3 ligase activity to maintain germline function in Caenorhabditis elegans.
Thapa P, Chikale RV, Szulc NA, Pandrea MT, Sztyler A, Jaggi K, Niklewicz M, Serwa RA, Hoppe T, Pokrzywa W.
J Biol Chem. 2024
Inflammation in Older Poles with Localized and Widespread Chronic Pain—Results from a Population-Based PolSenior Study.
Chudek A, Kotyla P, Kozak-Szkopek E, Mossakowska M, Wieczorowska-Tobis K, Sulicka-Grodzicka J, Olszanecka-Glinianowicz M, Chudek J, Owczarek AJ.
J Clin Med. 2024
Association between dietary variety and anthropometric parameters in community-dwelling older adults: results of a population-based PolSenior study.
Bylinowska J, Wierzbicka E, Białecka-Dębek A, Mossakowska M, Szybalska A, Pietruszka B.
Ann Agric Environ Med. 2024
The molecular dissection of TRIM25's RNA-binding mechanism provides key insights into its antiviral activity.
Álvarez L, Haubrich K, Iselin L, Gillioz L, Ruscica V, Lapouge K, Augsten S, Huppertz I, Choudhury NR, Simon B, Masiewicz P, Lethier M, Cusack S, Rittinger K, Gabel F, Leitner A, Michlewski G, Hentze MW, Allain FHT, Castello A, Hennig J.
Nat Commun. 2024
Transcriptome-Wide Analysis of mRNA Adenylation Status in Yeast Using Nanopore Sequencing.
Krawczyk PS, Tudek A, Mroczek S, Dziembowski A.
Methods Mol Biol. 2024
Advances in the field of RNA 3D structure prediction and modeling, with purely theoretical approaches, and with the use of experimental data.
Mukherjee S, Moafinejad SN, Badepally NG, Merdas K, Bujnicki JM.
Structure. 2024
Fibroblast growth factor 21 inversely correlates with survival in elderly population - the results of the Polsenior2 study.
Handzlik G, Owczarek AJ, Więcek A, Mossakowska M, Zdrojewski T, Chudek A, Olszanecka-Glinianowicz M, Chudek J.
Aging (Albany NY). 2024
Suitability of Adenosine Derivatives in Improving the Activity and Stability of Cytochrome c under Stress: Insights into the Effect of Phosphate Groups.
Bharadwaj P, Shet SM, Bisht M, Sarkar DK, Franklin G, Kotrappanavar NS, Mondal D.
J Phys Chem B. 2024
General and abdominal adiposity and hypertension in eight world regions: a pooled analysis of 837 population-based studies with 7·5 million participants.
NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M.
Lancet. 2024
Study of Biological Effects Induced in Solid Tumors by Shortened-Duration Thermal Ablation Using High-Intensity Focused Ultrasound.
Kaplińska-Kłosiewicz PM, Fura Ł, Kujawska T, Andrzejewski K, Kaczyńska K, Strzemecki D, Sulejczak M, Chrapusta SJ, Macias M, Sulejczak D.
Cancers (Basel). 2024
Whole-Exome Analysis for Polish Caucasian Patients with Retinal Dystrophies and the Creation of a Reference Genomic Database for the Polish Population.
Matczyńska E, Szymańczak R, Stradomska K, Łyszkiewicz P, Jędrzejowska M, Kamińska K, Beć-Gajowniczek M, Suchecka E, Zagulski M, Wiącek M, Wylęgała E, Machalińska A, Mossakowska M, Puzianowska-Kuźnicka M, Teper S, Boguszewska-Chachulska A.
Genes (Basel). 2024
Reinforcing Tunnel Network Exploration in Proteins Using Gaussian Accelerated Molecular Dynamics.
Mandal N, Surpeta B, Brezovsky J.
J Chem Inf Model. 2024
Optogenetic induction of mechanical muscle stress identifies myosin regulatory ubiquitin ligase NHL-1 in C. elegans.
Kutzner CE, Bauer KC, Lackmann JW, Acton RJ, Sarkar A, Pokrzywa W, Hoppe T.
Nat Commun. 2024
Floxuridine supports UPS independent of germline signaling and proteostasis regulators via involvement of detoxification in C. elegans.
Dubey AA, Sarkar A, Milcz K, Szulc NA, Thapa P, Piechota M, Serwa RA, Pokrzywa W.
PLoS Genet. 2024
Structural and biochemical characterization of cauliflower mosaic virus reverse transcriptase.
Prabaharan C, Figiel M, Szczepanowski RH, Skowronek K, Zajko W, Thangaraj V, Chamera S, Nowak E, Nowotny M.
J Biol Chem. 2024
Incorporating Prior Knowledge in the Seeds of Adaptive Sampling Molecular Dynamics Simulations of Ligand Transport in Enzymes with Buried Active Sites.
Sarkar DK, Surpeta B, Brezovsky J.
J Chem Theory Comput. 2024
Structural analysis of the BisI family of modification dependent restriction endonucleases.
Szafran K, Rafalski D, Skowronek K, Wojciechowski M, Kazrani AA, Gilski M, Xu SY, Bochtler M.
Nucleic Acids Res. 2024
Cytosine analogues as DNA methyltransferase substrates.
Wojciechowski M, Czapinska H, Krwawicz J, Rafalski D, Bochtler M.
Nucleic Acids Res. 2024
SARS-CoV-2 inhibitory potential of fish oil-derived 2-pyrone compounds by acquiring linoleic acid binding site on the spike protein.
Duragkar N, Chikhale R, Piechota M, Danta CC, Gandhale P, Itankar P, Chikhale S, Gurav N, Khan MS, Pokrzywa W, Thapa P, Bryce R, Gurav S.
Int J Biol Macromol. 2024
Hyperactive mTORC1 disrupts habenula function and light preference in zebrafish model of Tuberous sclerosis complex.
Doszyn O, Kedra M, Zmorzynska J.
iScience. 2024
Are there double knots in proteins? Prediction and in vitro verification based on TrmD-Tm1570 fusion from C. nitroreducens.
Perlinska AP, Nguyen ML, Pilla SP, Staszor E, Lewandowska I, Bernat A, Purta E, Augustyniak R, Bujnicki JM, Sulkowska JI.
Front Mol Biosci. 2024
TENT5-mediated polyadenylation of mRNAs encoding secreted proteins is essential for gametogenesis in mice.
Brouze M, Czarnocka-Cieciura A, Gewartowska O, Kusio-Kobiałka M, Jachacy K, Szpila M, Tarkowski B, Gruchota J, Krawczyk P, Mroczek S, Borsuk E, Dziembowski A.
Nat Commun. 2024
Computational analysis of congenital heart disease associated SNPs: Unveiling their impact on the gene regulatory system.
Vashisht S, Parisi C, Winata CL.
medRxiv. 2024
The molecular dissection of TRIM25‘s RNA-binding mechanism provides key insights into its antiviral activity.
Simon B, Castello A, Allain FHT, Hentze MW, Michlewski G, and 16 more authors
Research Square. 2024
The effect of infection with the entomopathogenic fungus Conidiobolus coronatus (Entomopthorales) on eighteen cytokine-like proteins in Galleria mellonella (Lepidoptera) larvae.
Wrońska AK, Kaczmarek A, Sobich J, Boguś MI.
Front Immunol. 2024
Autophagy initiation triggers p150Glued-AP-2β interaction on the lysosomes and facilitates their transport.
Tempes A, Bogusz K, Brzozowska A, Weslawski J, Macias M, Tkaczyk O, Orzoł K, Lew A, Calka-Kresa M, Bernas T, Szczepankiewicz AA, Mlostek M, Kumari S, Liszewska E, Machnicka K, Bakun M, Rubel T, Malik AR, Jaworski J.
Cell Mol Life Sci. 2024
SimRNAweb v2.0: a web server for RNA folding simulations and 3D structure modeling, with optional restraints and enhanced analysis of folding trajectories.
Moafinejad SN, de Aquino BRH, Boniecki MJ, Jeyeram IPNP, Nikolaev G, Magnus M, Farsani MA, Badepally NG, Wirecki TK, Stefaniak F, Bujnicki JM.
Nucleic Acids Res. 2024
Sex-specific relationships of inflammatory biomarkers with blood pressure in older adults.
Sulicka-Grodzicka J, Wizner B, Zdrojewski T, Mossakowska M, Puzianowska-Kuźnicka M, Chudek J, Więcek A, Korkosz M, Caiazzo E, Maffia P, Siedlinski M, Messerli FH, Guzik TJ.
Geroscience. 2024
Factors defining developmental competence of bovine oocytes collected for in vitro embryo production.
Pytel AT, Żyżyńska-Galeńska K, Gajewski Z, Papis K.
Biol Reprod. 2024
Characterization of winged helix domain fusion endonucleases as N6-methyladenine-dependent type IV restriction systems.
Helbrecht I, Heiter D, Yang W, Vincze T, Hanneman A, Lutz T, Ettwiller L, Bochtler M, Xu SY.
Front Microbiol. 2024
E3 ubiquitin ligase RNF2 protects polymerase ι from destabilization.
Fedorowicz M, Halas A, Macias M, Sledziewska-Gojska E, Woodgate R, McIntyre J.
Biochim Biophys Acta Mol Cell Res. 2024
Engineering of chimeric enzymes with expanded tolerance to ionic strength.
Mitkowski P, Jagielska E, Sabała I.
Microbiol Spectr. 2024
ARTEMIS: a method for topology-independent superposition of RNA 3D structures and structure-based sequence alignment.
Bohdan DR, Bujnicki JM, Baulin EF.
Nucleic Acids Res. 2024
Never-ending story of Brachyury: From short-tailed mice to tailless primates.
Korzh V.
Cells Dev. 2024
Structure-functional characterization of Lactococcus AbiA phage defense system.
Gapińska M, Zajko W, Skowronek K, Figiel M, Krawczyk PS, Egorov AA, Dziembowski A, Johansson MJO, Nowotny M.
Nucleic Acids Res. 2024
Circular extrachromosomal DNA in Euglena gracilis under normal and stress conditions.
Gumińska N, Hałakuc P, Zakryś B, Milanowski R.
Protist. 2024
AI is a viable alternative to high throughput screening: a 318-target study.
Participants of the Atomwise AIMS Program, including IIMCB researchers Stec N, Zhu S and Michlewski G.
Sci Rep. 2024
Targeting the EGFR pathway: An alternative strategy for the treatment of tuberous sclerosis complex?
Schachenhofer J, Gruber VE, Fehrer SV, Haider C, Glatter S, Liszewska E, Höftberger R, Aronica E, Rössler K, Jaworski J, Scholl T, Feucht M.
Neuropathol Appl Neurobiol. 2024
Diving into the zebrafish brain: exploring neuroscience frontiers with genetic tools, imaging techniques, and behavioral insights.
Doszyn O, Dulski T, Zmorzynska J.
Front Mol Neurosci. 2024
Pheromone-based communication influences the production of somatic extracellular vesicles in C. elegans
Szczepańska A, Olek K, Kołodziejska K, Yu J, Ibrahim AT, Adamkiewicz L, Schroeder FC, Pokrzywa W, Turek M.
Nat Commun. 2024
RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Di Zhang D, Czapinska H, Bochtler M, Wlodawer A, Lubkowski J.
Protein Sci. 2024
Despite the odds: formation of the SARS-CoV-2 methylation complex.
Matsuda A, Plewka J, Rawski M, Mourão A, Zajko W, Siebenmorgen T, Kresik L, Lis K, Jones AN, Pachota M, Karim A, Hartman K, Nirwal S, Sonani R, Chykunova Y, Minia I, Mak P, Landthaler M, Nowotny M, Dubin G, Sattler M, Suder P, Popowicz GM, Pyrć K, Czarna A.
Nucleic Acids Res. 2024
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 populationrepresentative studies with 222 million children, adolescents, and adults.
NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M.
Lancet. 2024
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex.
Kuzikov M, Reinshagen J, Wycisk K, Corona A, Esposito F, Malune P, Manelfi C, Iaconis D, Beccari A, Tramontano E, Nowotny M, Windshügel B, Gribbon P, Zaliani A.
Virus Res.. 2024
Mutant analysis of Kcng4b reveals how the different functional states of the voltage-gated potassium channel regulate ear development.
Jędrychowska J, Vardanyan V, Wieczor M, Marciniak A, Czub J, Amini R, Jain R, Shen H, Choi H, Kuznicki J, Korzh V.
Dev Biol. . 2024
Cryo-EM structure of rotavirus B NSP2 reveals its unique tertiary architecture.
Chamera S, Wycisk K, Czarnocki-Cieciura M, Nowotny M.
J Virol. 2024
Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1.
Czestkowski W, Krzemiński Ł, Piotrowicz MC, Mazur M, Pluta E, Andryianau G, Koralewski R, Matyszewski K, Olejniczak S, Kowalski M, Lisiecka K, Kozieł R, Piwowar K, Papiernik D, Nowotny M, Napiórkowska-Gromadzka A, Nowak E, Niedziałek D, Wieczorek G, Siwińska A, Rejczak T, Jędrzejczak K, Mulewski K, Olczak J, Zasłona Z, Gołębiowski A, Drzewicka K, Bartoszewicz A.
J Med Chem. 2024
Conserved structures and dynamics in 5'-proximal regions of Betacoronavirus RNA genomes.
de Moura TR, Purta E, Bernat A, Martín-Cuevas EM, Kurkowska M, Baulin EF, Mukherjee S, Nowak J, Biela AP, Rawski M, Glatt S, Moreno-Herrero F, Bujnicki JM.
Nucleic Acids Res.. 2024
Discovery of a trefoil knot in the RydC RNA: Challenging previous notions of RNA topology.
Niemyska W, Mukherjee S, Gren BA, Niewieczerzal S, Bujnicki JM, Sulkowska JI.
J Mol Biol.. 2024
MODOMICS: a database of RNA modifications and related information. 2023 update.
Cappannini A, Ray A, Purta E, Mukherjee S, Boccaletto P, Moafinejad SN, Lechner A, Barchet C, Klaholz BP, Stefaniak F, Bujnicki JM.
Nucleic Acids Res. . 2024
Iron-triggered signaling via ETS1 and the p38/JNK MAPK pathway regulates Bmp6 expression.
Zurawska G, Jończy A, Niklewicz M, Sas Z, Rumieńczyk I, Kulecka M, Piwocka K, Rygiel TP, Mikula M, Mleczko-Sanecka K.
Am J Hematol. 2024
Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner.
Janusz-Kaminska A, Brzozowska A, Tempes A, Urbanska M, Blazejczyk M, Miłek J, Kuzniewska B, Zeng J, Wesławski J, Kisielewska K, Bassell GJ, Jaworski J.
Mol Biol Cell.. 2024
Frailty and Survivability of Polish Caucasian Nonagenarians and Centenarians.
Skubiszewska A, Broczek K, Maruniak-Chudek I, Oledzka G, Jonas MI, Puzianowska-Kuznicka M, Mossakowska M.
Geriatrics. 2024
Mutation in the mitochondrial chaperone TRAP1 leads to autism with more severe symptoms in males.
Rydzanicz M, Kuzniewska B, Magnowska M, Wójtowicz T, Stawikowska A, Hojka A, Borsuk E, Meyza K, Gewartowska O, Gruchota J, Miłek J, Wardaszka P, Chojnicka I, Kondrakiewicz L, Dymkowska D, Puścian A, Knapska E, Dziembowski A, Płoski R, Dziembowska M.
EMBO Mol Med. 2024
Water will Find Its Way: Transport through Narrow Tunnels in Hydrolases.
Sequeiros-Borja C, Surpeta B, Thirunavukarasu AS, Dongmo Foumthuim CJ, Marchlewski I, Brezovsky J.
J Chem Inf Model. 2024
Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior.
Szewczyk LM, Lipiec MA, Liszewska E, Meyza K, Urban-Ciecko J, Kondrakiewicz L, Goncerzewicz A, Rafalko K, Krawczyk TG, Bogaj K, Vainchtein ID, Nakao-Inoue H, Puscian A, Knapska E, Sanders SJ, Jan Nowakowski T, Molofsky AV, Wisniewska MB.
Mol Psychiatry. 2024
scRNA-seq reveals the diversity of the developing cardiac cell lineage and molecular players in heart rhythm regulation.
Abu Nahia K, Sulej A, Migdał M, Ochocka N, Ho R, Kamińska B, Zagorski M, Winata CL.
iScience. 2024
DEGRONOPEDIA: a web server for proteome-wide inspection of degrons.
Szulc NA, Stefaniak F, Piechota M, Soszyńska A, Piórkowska G, Cappannini A, Bujnicki JM, Maniaci C, Pokrzywa W.
Nucleic Acids Res. 2024
2023
Dendritic arbor dynamics and stability in health and disease.
Mlostek M, Zeng J, Urbanska M, Jaworski J.
Acta Neurobiol Exp (Wars). 2023
Identification of cardiac-related serum miRNA in patients with type 2 diabetes mellitus and heart failure: Preliminary report.
Wrzosek M, Hojka-Osińska A, Klimczak-Tomaniak D, Żarek-Starzewska AK, Dyrla W, Rostek-Bogacka M, Wróblewski M, Kuch M, Kucia M.
Adv Clin Exp Med.. 2023
DesiRNA: structure-based design of RNA sequences with a Monte Carlo approach.
Wirecki T, Lach G, Jaryani F, Badepally NG, Moafinejad SN, Klaudel G, Bujnicki JM.
bioRxiv. 2023
SQUARNA - an RNA secondary structure prediction method based on a greedy stem formation model.
Bohdan DR, Nikolaev GI, Bujnicki JM, Baulin EF
bioRxiv. 2023
Multiple Myeloma associated DIS3 mutations drive AID-dependent IgH Translocations.
Kulinski TM, Gewartowska O, Mahe M, Kasztelan K, Durys J, Seraphin B, Dziembowski A.
bioRxiv. 2023
Rational engineering of binding pocket’s structure and dynamics in penicillin G acylase for selective degradation of bacterial signaling molecules.
Grulich M, Surpeta B, Palyzová A, Marešová H, Zahradník J, Brezovsky J.
bioRxiv. 2023
Impact of water models on structure and dynamics of ligand-transport tunnels in enzymes derived from molecular dynamics simulations.
Agrawal N, Brezovsky J.
bioRxiv. 2023
Spatial and single-cell transcriptomics illuminate bat immunity and barrier tissue evolution.
Levinger R, Tussia-Cohen D, Friedman S, Lender Y, Nissan Y, Fraimovitch E, Gavriel Y, Tearle J, Kolodziejczyk AA, Gomes T, Kunowska N, Weinberg M, Donati G, James KR, Yovel Y, Hagai T.
bioRxiv. 2023
Staphylococcus aureus sacculus mediates activities of M23 hydrolases.
Razew A, Laguri C, Vallet A, Bougault C, Kaus-Drobek M, Sabala I, Simorre JP.
Nat Commun. 2023
Ammonia inhibits antitumor activity of NK cells by decreasing mature perforin.
Domagala J, Grzywa TM, Baranowska I, Kusowska A, Fidyt K, Marhelava K, Pilch Z, Graczyk-Jarzynka A, Picard LK, Jastrzebski K, Granica M, Justyniarska M, Urlaub D, Bobrowicz M, Miaczynska M, Watzl C, Winiarska M.
bioRxiv. 2023
SAM, SAH and C. elegans longevity: insights from a partial AHCY deficiency model.
Thapa P, Olek K, Kowalska A, Serwa RA, Pokrzywa W.
NPJ Aging. 2023
Molecular EPISTOP, a comprehensive multi-omic analysis of blood from Tuberous Sclerosis Complex infants age birth to two years.
Huschner F, Głowacka-Walas J, Mills JD, Klonowska K, Lasseter K, Asara JM, Moavero R, Hertzberg C, Weschke B, Riney K, Feucht M, Scholl T, Krsek P, Nabbout R, Jansen AC, Petrák B, van Scheppingen J, Zamecnik J, Iyer A, Anink JJ, Mühlebner A, Mijnsbergen C, Lagae L, Curatolo P, Borkowska J, Sadowski K, Domańska-Pakieła D, Blazejczyk M, Jansen FE, Janson S, Urbanska M, Tempes A, Janssen B, Sijko K, Wojdan K, Jozwiak S, Kotulska K, Lehmann K, Aronica E, Jaworski J, Kwiatkowski DJ.
Nat Commun.. 2023
Modification of DNA by a viral enzyme and charged tRNA.
Silva RMB, Slyvka A, Lee Y-J, Guan C, Lund SR, Raleigh EA, Skowronek K, Bochtler M, Weigele PR.
bioRxiv. 2023
Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c.
NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M.
Nat Med.. 2023
mRNA decay can be uncoupled from deadenylation during stress response.
Czarnocka-Cieciura A, Turtola M, Tomecki R, Krawczyk P, Mroczek S, Orzeł W, Saha U, Jensen TH, Dziembowski A, Tudek A.
bioRxiv. 2023
Structure of human TRPM8 channel.
Palchevskyi S, Czarnocki-Cieciura M, Vistoli G, Gervasoni S, Nowak E, Beccari AR, Nowotny M, Talarico C.
Commun Biol.. 2023
The Bacteroidetes Q-rule and glutaminyl cyclase activity increase the stability of extracytoplasmic proteins.
Szczęśniak K, Veillard F, Scavenius C, Chudzik K, Ferenc K, Bochtler M, Potempa J, Mizgalska D.
mBio.. 2023
Liver sinusoidal endothelial cells constitute a major route for hemoglobin clearance.
Zurawska G, Sas Z, Jończy A, Slusarczyk P, Mahadeva R, Chwałek M, Kulecka M, Rumieńczyk I, Moulin M, Jastrzębski K, Mikula M, Etzerodt A, Miączyńska M, Rygiel TP, Mleczko-Sanecka K.
bioRxiv. 2023
Anemia, Iron Deficiency, and Iron Regulators in Pancreatic Ductal Adenocarcinoma Patients: A Comprehensive Analysis.
Osmola M, Gierej B, Mleczko-Sanecka K, Jończy A, Ciepiela O, Kraj L, Ziarkiewicz-Wróblewska B, Basak GW.
Curr Oncol.. 2023
Sterility-Independent Enhancement of Proteasome Function via Floxuridine-Triggered Detoxification in C. elegans.
Dubey AA, Szulc NA, Piechota M, Serwa RA, Pokrzywa W.
bioRxiv. 2023
Lysine deserts and cullin-RING ligase receptors: Navigating untrodden paths in proteostasis.
Szulc NA, Piechota M, Biriczova L, Thapa P, Pokrzywa W.
iScience. 2023
Nano-structured hydrotrope-caged cytochrome c with boosted stability in harsh environments: a molecular insight.
Bharadwaj P, Sarkar DK, Bisht M, Shet SM, Kotrappanavar NS, Lokesh V, Franklin G, Brezovsky J, Mondal D.
Green Chem.. 2023
Significant improvements in cataract treatment and persistent inequalities in access to cataract surgery among older Poles from 2009 to 2019: results of the PolSenior and PolSenior2 surveys.
Lange N, Kujawska-Danecka H, Wyszomirski A, Suligowska K, Lange A, Raczyńska D, Jędrychowska-Jamborska J, Mossakowska M.
Front. Public Health. 2023
Diminishing benefits of urban living for children and adolescents' growth and development.
NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M.
Nature. 2023
Toward an understanding of the conformational plasticity of S100A8 and S100A9 Ca2+-binding proteins.
Polakowska M, Steczkiewicz K, Szczepanowski RH, Wysłouch-Cieszyńska A.
J Biol Chem. 2023
Rep protein accommodates together dsDNA and ssDNA which enables a loop-back mechanism to plasmid DNA replication initiation.
Wegrzyn K, Oliwa M, Nowacka M, Zabrocka E, Bury K, Purzycki P, Czaplewska P, Pipka J, Giraldo R, Konieczny I.
Nucleic Acids Res.. 2023
RNA tertiary structure prediction in CASP15 by the GeneSilico group: Folding simulations based on statistical potentials and spatial restraints.
Baulin EF, Mukherjee S, Moafinejad SN, Wirecki TK, Badepally NG, Jaryani F, Stefaniak F, Amiri Farsani M, Ray A, Rocha de Moura T, Bujnicki JM.
Proteins. 2023
RNA 3D structure modeling by fragment assembly with small-angle X-ray scattering restraints.
Chojnowski G, Zaborowski R, Magnus M, Mukherjee S, Bujnicki JM.
Bioinformatics. 2023
RNA target highlights in CASP15: Evaluation of predicted models by structure providers.
Kretsch RC, Andersen ES, Bujnicki JM, Chiu W, Das R, Luo B, Masquida B, McRae EKS, Schroeder GM, Su Z, Wedekind JE, Xu L, Zhang K, Zheludev IN, Moult J, Kryshtafovych A.
Proteins. 2023
Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing.
Luo BN et al. with Bujnicki JM.
Nature Catalysis. 2023
A comprehensive survey of long-range tertiary interactions and motifs in non-coding RNA structures.
Bohdan DR, Voronina VV, Bujnicki JM, Baulin EF.
Nucleic Acids Res.. 2023
Generation of two human iPSC lines from dermal fibroblasts of adult- and juvenile-onset Huntington's disease patients and two healthy donors.
Piechota M, Latoszek E, Liszewska E, Hansíková H, Klempíř J, Mühlbäck A, Landwehrmeyer GB, Kuźnicki J, Czeredys M.
Stem Cell Res.. 2023
The prolyl isomerase Pin1 stabilizes NeuroD during differentiation of mechanoreceptors.
Zhao L, Fong S, Yang Q, Jiang YJ, Korzh V, Liou YC.
Front Cell Dev Biol. 2023
Lack of Stim2 Affects Vision-Dependent Behavior and Sensitivity to Hypoxia.
Wasilewska I, Majewski L, Adamek-Urbańska D, Mondal SS, Baranykova S, Gupta RK, Bielecki D, Winata CL, Kuznicki J.
Zebrafish. 2023
Comparison of antiviral responses in two bat species reveals conserved and divergent innate immune pathways.
Schneor L, Kaltenbach S, Friedman S, Tussia-Cohen D, Nissan Y, Shuler G, Fraimovitch E, Kolodziejczyk AA, Weinberg M, Donati G, Teeling EC, Yovel Y, Hagai T.
iScience. 2023
Bicarbonate Activation of the Monomeric Photosystem II-PsbS/Psb27 Complex.
Fantuzzi A, Haniewicz P, Farci D, Loi MC, Park K, Büchel C, Bochtler M, Rutherford AW, Piano D.
Plant Physiol.. 2023
Structural interaction fingerprints and machine learning for predicting and explaining binding of small molecule ligands to RNA.
Szulc NA, Mackiewicz Z, Bujnicki JM, Stefaniak F.
Brief Bioinform.. 2023
In silico analysis of the profilaggrin sequence indicates alterations in the stability, degradation route, and intracellular protein fate in filaggrin null mutation carriers.
Paul AA, Szulc NA, Kobiela A, Brown SJ, Pokrzywa W, Gutowska-Owsiak D.
Front. Mol. Biosci.. 2023
Mechanism of RecF–RecO–RecR cooperation in bacterial homologous recombination.
Nirwal S, Czarnocki-Cieciura M, Chaudhary A, Zajko W, Skowronek K, Chamera S, Figiel M, Nowotny M.
Nat Struct Mol Biol.. 2023
Arginase 1/2 inhibitor OATD-02: from discovery to first-in-man setup in cancer immunotherapy.
Borek B, Nowicka J, Gzik A, Dziegielewski M, Jedrzejczak K, Brzezinska J, Grzybowski M, Stanczak P, Pomper P, Zagozdzon A, Rejczak T, Matyszewski K, Golebiowski A, Olczak J, Lisiecki K, Tyszkiewicz M, Kania M, Piasecka S, Cabaj A, Dera P, Mulewski K, Chrzanowski J, Kusmirek D, Sobolewska E, Magdycz M, Mucha L, Masnyk M, Golab J, Nowotny M, Nowak E, Napiorkowska-Gromadzka A, Pikul S, Jazwiec R, Dzwonek K, Dobrzanski P, Meyring M, Skowronek K, Iwanowski P, Zaslona Z, Blaszczyk R.
Mol Cancer Ther.. 2023
Restriction of access to the central cavity is a major contributor to substrate selectivity in plant ABCG transporters.
Pakuła K, Sequeiros-Borja C, Biała-Leonhard W, Pawela A, Banasiak J, Bailly A, Radom M, Geisler M, Brezovsky J, Jasiński M.
Cell Mol Life Sci.. 2023
Structural basis of sRNA RsmZ regulation of Pseudomonas aeruginosa virulence.
Jia X, Pan Z, Yuan Y, Luo B, Luo Y, Mukherjee S, Jia G, Liu L, Ling X, Yang X, Miao Z, Wei X, Bujnicki JM, Zhao K, Su Z.
Cell Res.. 2023
Impaired iron recycling from erythrocytes is an early hallmark of aging.
Slusarczyk P, Mandal PK, Zurawska G, Niklewicz M, Chouhan K, Mahadeva R, Jończy A, Macias M, Szybinska A, Cybulska-Lubak M, Krawczyk O, Herman S, Mikula M, Serwa R, Lenartowicz M, Pokrzywa W, Mleczko-Sanecka K.
eLife. 2023
Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish.
Uszczynska-Ratajczak B, Sugunan S, Kwiatkowska M, Migdal M, Carbonell-Sala S, Sokol A, Winata CL, Chacinska A.
Life Sci Alliance. 2023
Lysine-deficient proteome can be regulated through non-canonical ubiquitination and ubiquitin-independent proteasomal degradation.
Szulc N, Piechota M, Thapa P, Pokrzywa W.
bioRxiv. 2023
xcore: an R package for inference of gene expression regulators.
Migdał M, Arakawa T, Takizawa S, Furuno M, Suzuki H, Arner E, Winata CL, Kaczkowski B.
BMC Bioinformatics.. 2023
The national burden of frailty and disproportionate distribution of its components-the predominance of slow gait speed: a 2018-19 face-to-face epidemiologic assessment representative of population of older Poles.
Piotrowicz K, Kujawska-Danecka H, Jagiełło K, Hajduk A, Skalska A, Mossakowska M, Zdrojewski T, Grodzicki T, Gąsowski J.
Aging Clin Exp Res.. 2023
Preparation of Caenorhabditis elegans for Scoring of Muscle-derived Exophers.
Banasiak K, Turek M, Pokrzywa W.
bio-protocol Journal. 2023
Clustered PHD domains in KMT2/MLL proteins are attracted by H3K4me3 and H3 acetylation-rich active promoters and enhancers.
Stroynowska-Czerwinska AM, Klimczak M, Pastor M, Kazrani AA, Misztal K, Bochtler M.
Cell Mol Life Sci. 2023
Divide-and-conquer approach to study protein tunnels in long molecular dynamics simulations.
Sequeiros-Borja C, Surpeta B, Marchlewski I, Brezovsky J.
MethodsX. 2023
TRIM25 mutation (p.C168*), coding for an E3 ubiquitin ligase, is a cause of early-onset autosomal dominant dementia with amyloid load and parkinsonism.
Gómez-Tortosa E, Baradaran-Heravi Y, Dillen L, Choudhury NR, Agüero Rabes P, Pérez-Pérez J, Kocoglu C, Sainz MJ, Ruiz González A, Téllez R, Cremades-Jimeno L, Cárdaba B; EU EOD Consortium, Van Broeckhoven C, Michlewski G, van der Zee J.
Alzheimers Dement.. 2023
Development of the brain ventricular system from a comparative perspective.
Korzh V.
Clin Anat.. 2023
NACDDB: Nucleic Acid Circular Dichroism Database.
Cappannini A, Mosca K, Mukherjee S, Moafinejad SN, Sinden RR, Arluison V, Bujnicki J, Wien F.
Nucleic Acids Res.. 2023
1D2DSimScore: A novel method for comparing contacts in biomacromolecules and their complexes.
Moafinejad SN,
Protein Sci.. 2023
A novel de novo FEM1C variant is linked to neurodevelopmental disorder with absent speech, pyramidal signs, and limb ataxia.
Dubey AA, Krygier M, Szulc NA, Rutkowska K, Kosińska J, Pollak A, Rydzanicz M, Kmieć T, Mazurkiewicz-Bełdzińska M, Pokrzywa W, Płoski R.
Hum Mol Genet.. 2023
Out-of-pocket expenses of patients with inflammatory bowel disease: a comparison of patient-reported outcomes across 12 European countries.
Holko P, Kawalec P, Sajak-Szczerba M, Avedano L, Mossakowska M.
Eur J Health Econ.. 2023
Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding.
Hyjek-Składanowska M, Anderson BA, Mykhaylyk V, Orr C, Wagner A, Poznański JT, Skowronek K, Seth P, Nowotny M.
Nucleic Acids Res.. 2023
Measuring the tail: Methods for poly(A) tail profiling.
Brouze A, Krawczyk PS, Dziembowski A, Mroczek S.
Wiley Interdiscip Rev RNA.. 2023
Indirect Costs of Inflammatory Bowel Diseases: A Comparison of Patient-Reported Outcomes Across 12 European Countries.
Holko P, Kawalec P, Sajak-Szczerba M, Avedano L, Mossakowska M.
Inflamm Bowel Dis.. 2023
2022
ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway
Wróbel M, Cendrowski J, Szymańska E, Grębowicz-Maciukiewicz M, Budick-Harmelin N, Macias M, Szybińska A, Mazur M, Kolmus K, Goryca K, Dąbrowska M, Paziewska A, Mikula M, Miączyńska M.
Life Sci Alliance. 2022
Quaternary organization of the human eEF1B complex reveals unique multi-GEF domain assembly.
Bondarchuk TV, Shalak VF, Lozhko DM, Fatalska A, Szczepanowski RH, Liudkovska V, Tsuvariev OY, Dadlez M, El'skaya AV, Negrutskii BS.
Nucleic Acids Res. 2022
Zebrafish/Drosophila Dual System Model for Investigating Human Microcephaly.
Bartoszewski S, Dawidziuk M, Kasica N, Durak R, Jurek M, Podwysocka A, Guilbride DL, Podlasz P, Winata CL, Gawlinski PA.
Cells. 2022
Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.
Baranasic D, Hörtenhuber M, Balwierz PJ, Zehnder T, Mukarram AK, Nepal C, Várnai C, Hadzhiev Y, Jimenez-Gonzalez A, Li N, Wragg J, D'Orazio FM, Relic D, Pachkov M, Díaz N, Hernández-Rodríguez B, Chen Z, Stoiber M, Dong M, Stevens I, Ross SE, Eagle A, Martin R, Obasaju O, Rastegar S, McGarvey AC, Kopp W, Chambers E, Wang D, Kim HR, Acemel RD, Naranjo S, Łapiński M, Chong V, Mathavan S, Peers B, Sauka-Spengler T, Vingron M, Carninci P, Ohler U, Lacadie SA, Burgess SM, Winata C, van Eeden F, Vaquerizas JM, Gómez-Skarmeta JL, Onichtchouk D, Brown BJ, Bogdanovic O, van Nimwegen E, Westerfield M, Wardle FC, Daub CO, Lenhard B, Müller F.
Nat Genet. 2022
Obesity in Caucasian Seniors on the Rise: Is It Truly Harmful? Results of the PolSenior2 Study.
Puzianowska-Kuznicka M, Kurylowicz A, Wierucki L, Owczarek AJ, Jagiello K, Mossakowska M, Zdrojewski T, Chudek J.
Nutrients. 2022
Pheromone-dependent olfaction bidirectionally regulates muscle extracellular vesicles formation.
Banasiak K, Szczepańska A, Kołodziejska K, Ibrahim AT, Pokrzywa W, Turek M.
bioRxiv. 2022
Electrostatic Interaction with the Bacterial Cell Envelope Tunes the Lytic Activity of Two Novel Peptidoglycan Hydrolases.
Wysocka A, Łężniak Ł, Jagielska E, Sabała I.
Microbiol Spectr. 2022
Dynactin interaction with AP-2 adaptor complex requires CLIP-170 and autophagy.
Tempes A, Bogusz K, Brzozowska A, Weslawski J, Macias M, Lew A, Calka-Kresa M, Bernas T, Szczepankiewicz AA, Bakun M, Rubel T, Malik AR, Jaworski J.
bioRxiv. 2022
Mitofusin 2 Integrates Mitochondrial Network Remodelling, Mitophagy and Renewal of Respiratory Chain Proteins in Neurons after Oxygen and Glucose Deprivation.
Wojtyniak P, Boratynska-Jasinska A, Serwach K, Gruszczynska-Biegala J, Zablocka B, Jaworski J, Kawalec M.
Mol Neurobiol. 2022
Modeling the Structure, Dynamics, and Transformations of Proteins with the UNRES Force Field.
Sieradzan AK, Czaplewski C, Krupa P, Mozolewska MA, Karczyńska AS, Lipska AG, Lubecka EA, Gołaś E, Wirecki T, Makowski M, Ołdziej S, Liwo A.
Methods Mol Biol. 2022
Computational Pipeline for Reference-Free Comparative Analysis of RNA 3D Structures Applied to SARS-CoV-2 UTR Models.
Gumna J, Antczak M, Adamiak RW, Bujnicki JM, Chen SJ, Ding F, Ghosh P, Li J, Mukherjee S, Nithin C, Pachulska-Wieczorek K, Ponce-Salvatierra A, Popenda M, Sarzynska J, Wirecki T, Zhang D, Zhang S, Zok T, Westhof E, Miao Z, Szachniuk M, Rybarczyk A.
Int J Mol Sci. 2022
MicroRNA Expression Profile in TSC Cell Lines and the Impact of mTOR Inhibitor.
Pawlik B, Grabia S, Smyczyńska U, Fendler W, Dróżdż I, Liszewska E, Jaworski J, Kotulska K, Jóźwiak S, Młynarski W, Trelińska J.
Int J Mol Sci. 2022
TENT5 cytoplasmic noncanonical poly(A) polymerases regulate the innate immune response in animals.
Liudkovska V, Krawczyk PS, Brouze A, Gumińska N, Wegierski T, Cysewski D, Mackiewicz Z, Ewbank JJ, Drabikowski K, Mroczek S, Dziembowski A.
Sci Adv. 2022
Disrupting interaction between miR-132 and Mmp9 3'UTR improves synaptic plasticity and memory in mice.
Kuzniewska B, Rejmak K, Nowacka A, Ziółkowska M, Milek J, Magnowska M, Gruchota J, Gewartowska O, Borsuk E, Salamian A, Dziembowski A, Radwanska K, Dziembowska M.
Front Mol Neurosci. 2022
Competition between electrostatic interactions and halogen bonding in the protein–ligand system: structural and thermodynamic studies of 5,6-dibromobenzotriazole-hCK2α complexes.
Winiewska‑Szajewska M, Czapinska H, Kaus‑Drobek M, Fricke A, Mieczkowska K, Dadlez M, Bochtler M, Poznański J.
Sci Rep. 2022
The Prevalence of Anticitrullinated Protein Antibodies in Older Poles—Results from a Population-Based PolSenior Study
Chudek A, Kotyla P, Mossakowska M, Grodzicki T,
Zdrojewski T, Olszanecka-Glinianowicz M, Chudek J, Owczarek AJ.
Int J Environ Res Public Health. 2022
Evidence for a fragile X messenger ribonucleoprotein 1 (FMR1) mRNA gain-of-function toxicity mechanism contributing to the pathogenesis of fragile X-associated premature ovarian insufficiency.
Rosario R, Stewart HL, Choudhury NR, Michlewski G, Charlet-Berguerand N, Anderson RA.
FASEB J. 2022
Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes.
Sekar R, Motzler K, Kwon Y, Novikoff A, Jülg J, Najafi B, Wang S, Warnke AL, Seitz S, Hass D, Gancheva S, Kahl S, Yang B, Finan B, Schwarz K, Okun JG, Roden M, Blüher M, Müller TD, Krahmer N, Behrends C, Plettenburg O, Miaczynska M, Herzig S, Zeigerer A.
Cell Metab. 2022
Generation of three human iPSC lines from patients with Huntington’s disease with different CAG lengths and human control iPSC line from a healthy donor.
Latoszek E, Piechota M, Liszewska E, Hansíkova ́H, Klempír J,
Mühlback A, Landwehrmeyer GB, Kuznicki J, Czeredys M.
Stem Cell Res. 2022
Prevalence and risk factors of untreated thyroid dysfunctions in the older Caucasian adults: Results of PolSenior 2 survey.
Kocełak P, Mossakowska M, Puzianowska-Kuźnicka M, Sworczak K, Wyszomirski A, Handzlik G, Stefański A, Zdrojewski T, Chudek J.
PLoS One. 2022
Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function.
Ravichandran M, Rafalski D, Davies CI, Ortega-Recalde O, Nan X, Glanfield CR, Kotter A, Misztal K, Wang AH, Wojciechowski M, Rażew M, Mayyas IM, Kardailsky O, Schwartz U, Zembrzycki K, Morison IM, Helm M, Weichenhan D, Jurkowska RZ, Krueger F, Plass C, Zacharias M, Bochtler M, Hore TA, Jurkowski TP.
Sci Adv. 2022
The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells.
Oroń M, Grochowski M, Jaiswar A, Legierska J, Jastrzębski K, Nowak-Niezgoda M, Kołos M, Kaźmierczak W, Olesiński T, Lenarcik M, Cybulska M, Mikula M, Żylicz A, Miączyńska M, Zettl K, Wiśniewski JR, Walerych D.
Cell Rep. 2022
Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish.
Niescierowicz K#, Pryszcz L#, Navarrete C#, Tralle E#, Sulej A#, Abu Nahia K, Kasprzyk ME, Misztal K, Pateria A, Pakuła A, Bochtler M, Winata C.
# Contributed equally
Nat Commun. 2022
miRNAs and isomiRs: Serum-Based Biomarkers for the Development of Intellectual Disability and Autism Spectrum Disorder in Tuberous Sclerosis Complex.
Scheper M, Romagnolo A, Besharat ZM, Iyer AM, Moavero R, Hertzberg C, Weschke B, Riney K, Feucht M, Scholl T, Petrak B, Maulisova A, Nabbout R, Jansen AC, Jansen FE, Lagae L, Urbanska M, Ferretti E, Tempes A, Blazejczyk M, Jaworski J, Kwiatkowski DJ, Jozwiak S, Kotulska K, Sadowski K, Borkowska J, Curatolo P, Mills JD, Aronica E, Epistop Consortium Members.
Biomedicines. 2022
Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Figiel M, Gapińska M, Czarnocki-Cieciura M, Zajko W, Sroka M, Skowronek K, Nowotny M.
Nucleic Acids Res. 2022
Mortality of older persons with and without abnormalities in the physical examination of arterial system.
Aging Clin Exp Res. . 2022
A Dimer-Monomer Switch Controls CHIP-Dependent Substrate Ubiquitylation and Processing.
Mol Cell. 2022
The Nε-rule for serine, but not cysteine catalytic triads.
Czapińska H, Bochtler M.
Angew Chem Int Ed Engl. 2022
Loss of Unconventional Myosin VI Affects cAMP/PKA Signaling in Hindlimb Skeletal Muscle in an Age-Dependent Manner.
Front Physiol. 2022
Ferritin-mediated iron detoxification promotes hypothermia survival in Caenorhabditis elegans and murine neurons.
Pekec T, Lewandowski J, Komur AA, Sobańska D, Guo Y, Świtońska-Kurkowska K, Małecki JM, Dubey AA, Pokrzywa W, Frankowski M, Figiel M, Ciosk R.
Nat Commun. 2022
Tollip-deficient zebrafish display no abnormalities in development, organ morphology or gene expression in response to lipopolysaccharide.
Wolińska-Nizioł L, Romaniuk K, Wojciechowska K, Surga K, Kamaszewski M, Szudrowicz H, Miączyńska M.
FEBS Open Bio. 2022
A long noncoding RNA promotes parasite differentiation in African trypanosomes.
Guegan F, Rajan KS, Bento F, Pinto-Neves D, Sequeira M, Gumińska N, Mroczek S, Dziembowski A, Cohen-Chalamish S, Doniger T, Galili B, Estévez AM, Notredame C, Michaeli S, Figueiredo LM.
Sci Adv. 2022
Higher ATM expression in lymphoblastoid cell lines from centenarian compared with younger women.
Hadar A, Voinsky I, Parkhomenko O, Puzianowska-Kuźnicka M, Kuźnicki J, Gozes I, Gurwitz D.
Drug Dev Res. 2022
TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway.
*Choudhury NR, *Trus I, *Heikel G, Wolczyk M, Szymanski J, Bolembach A, Dos Santos Pinto RM, Smith N, Trubitsyna M, Gaunt E, Digard P, Michlewski G.
*joint first authors
Nucleic Acids Res. 2022
Structural basis of transposon end recognition explains central features of Tn7 transposition systems.
Kaczmarska Z, Czarnocki-Cieciura M, Górecka-Minakowska KM, Wingo RJ, Jackiewicz J, Zajko W, Poznański JT, Rawski M, Grant T, Peters JE, Nowotny M.
Mol Cell.. 2022
fingeRNAt-A novel tool for high-throughput analysis of nucleic acid-ligand interactions.
Szulc NA, Mackiewicz Z, Bujnicki JM, Stefaniak F.
PLoS Comput Biol.. 2022
Molecular insights into RNA recognition and gene regulation by the TRIM-NHL protein Mei-P26.
Salerno-Kochan A, Horn A, Ghosh P, Nithin C, Kościelniak A, Meindl A, Strauss D, Krutyhołowa R, Rossbach O, Bujnicki JM, Gaik M, Medenbach J, Glatt S.
Life Sci Alliance. 2022
Endocytic trafficking of GAS6-AXL complexes is associated with sustained AKT activation.
Poświata A, Kozik K, Miączyńska M, Zdżalik-Bielecka D.
Cell Mol Life Sci. 2022
CHIP ubiquitin ligase is involved in the nucleolar stress management.
Piechota M, Biriczova L, Kowalski K, Szulc NA, Pokrzywa W.
bioRxiv preprint. 2022
Common Dynamic Determinants Govern Quorum Quenching Activity in N-Terminal Serine Hydrolases.
Surpeta B, Grulich M, Palyzová A, Marešová H, Brezovsky J.
ACS Catal. 2022
SRF depletion in early life contributes to social interaction deficits in the adulthood.
Roszkowska M, Krysiak A, Majchrowicz L, Nader K, Beroun A, Michaluk P, Pekala M, Jaworski J, Kondrakiewicz L, Puścian A, Knapska E, Kaczmarek L, Kalita K.
Cell Mol Life Sci. 2022
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities.
Corona A, Wycisk K, Talarico C, Manelfi C, Milia J, Cannalire R, Esposito F, Gribbon P, Zaliani A, Iaconis D, Beccari AR, Summa V, Nowotny M, Tramontano E.
ACS Pharmacol Transl Sci. 2022
DNAzymeBuilder, a web application for in situ generation of RNA/DNA-cleaving deoxyribozymes.
Mohammadi-Arani R, Javadi-Zarnaghi F, Boccaletto P, Bujnicki JM, Ponce-Salvatierra A.
Nucleic Acids Res. 2022
The Pet127 protein is a mitochondrial 5'-to-3' exoribonuclease from the PD-(D/E)XK superfamily involved in RNA maturation and intron degradation in yeasts.
Labedzka-Dmoch K, Razew M, Gapinska M, Piatkowski J, Kolondra A, Salmonowicz H, Wenda JM, Nowotny M, Golik P.
RNA. 2022
Benchtop X-band electron paramagnetic resonance detection of melanin and Nitroxyl spin probe in zebrafish.
Makarova K, Zawada K, Wiweger M.
Free Radical Biology and Medicine. 2022
Siah‑1‑interacting protein regulates mutated huntingtin protein aggregation in Huntington’s disease models.
Latoszek E, Wiweger M, Ludwiczak J, Dunin‑Horkawicz S, Kuznicki J, Czeredys M.
Cell & Bioscience. 2022
Polypharmacy in Polish Older Adult Population-A Cross-Sectional Study: Results of the PolSenior Project.
Neumann-Podczaska A, Tobis S, Antimisiaris D, Mossakowska M, Puzianowska-Kuznicka M, Chudek J, Wierucki L, Merks P, Wizner B, Sobieszczanska M, Niemir ZI, Kaczmarek B, Wieczorowska-Tobis K.
Int J Environ Res Public Health.. 2022
TransportTools: a library for high-throughput analyses of internal voids in biomolecules and ligand transport through them.
Bioinformatics. 2022
Bemcentinib and gilteritinib inhibit cell growth and impair the endo-lysosomal and autophagy systems in an AXL-independent manner.
Zdzalik-Bielecka D, Kozik K, Poswiata A, Jastrzebski K, Jakubik M, Miaczynska M.
Mol Cancer Res. . 2022
Disparate effects of ankle‑brachial index on mortality in the ‘very old’ and ‘younger old’ populations‑the PolSenior survey.
Królczyk J, Skalska A, Piotrowicz K, Mossakowska M, Grodzicki T, Gąsowski J.
Heart Vessels. 2022
A heterotypic assembly mechanism regulates CHIP E3 ligase activity.
Das A, Thapa P, Santiago U, Shanmugam N, Banasiak K, Dabrowska K, Nolte H, Szulc NA, Gathungu RM, Cysewski D, Krüger M, Dadlez M, Nowotny M, Camacho CJ, Hoppe T, Pokrzywa W.
EMBO J. . 2022
2021
Socioeconomic Risk Factors of Poor Nutritional Status in Polish Elderly Population: The Results of PolSenior2 Study.
Krzymińska-Siemaszko R, Deskur-Śmielecka E, Kaluźniak-Szymanowska A, Kaczmarek B, Kujawska-Danecka H, Klich-Rączka A, Mossakowska M, Małgorzewicz S, Dworak LB, Kostka T, Chudek J, Wieczorowska-Tobis K.
Nutrients.. 2021
Annexin A3: a newly identified player in store‑operated calcium entry.
Dyrda A, Kuznicki J, Majewski L.
Acta Neurobiol Exp . 2021
Multi-omics analyses of early liver injury reveals cell-type-specific transcriptional and epigenomic shift.
Migdał M, Tralle E, Abu Nahia K, Bugajski Ł, Kędzierska KZ, Garbicz F, Piwocka K, Winata CL, Pawlak M.
BMC Genomics.. 2021
Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae.
Turtola M, Manav MC, Kumar A, Tudek A, Mroczek S, Krawczyk PS, Dziembowski A, Schmid M, Passmore LA, Casañal A, Jensen TH.
Genes Dev.. 2021
Chemotherapy of HER2- and MDM2-Enriched Breast Cancer Subtypes Induces Homologous Recombination DNA Repair and Chemoresistance.
Herok M, Wawrzynow B, Maluszek MJ, Olszewski MB, Zylicz A, Zylicz M.
Cancers (Basel). 2021
Modular self-assembly system for development of oligomeric, highly internalizing and potent cytotoxic conjugates targeting fibroblast growth factor receptors.
Poźniak M, Porębska N, Jastrzębski K, Krzyścik MA, Kucińska M, Zarzycka W, Barbach A, Zakrzewska M, Otlewski J, Miączyńska M, Opaliński Ł.
J Biomed Sci.. 2021
The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis.
Scheer H, de Almeida C, Ferrier E, Simonnot Q, Poirier L, Pflieger D, Sement FM, Koechler S, Piermaria C, Krawczyk P, Mroczek S, Chicher J, Kuhn L, Dziembowski A, Hammann P, Zuber H, Gagliardi D.
Nat Commun.. 2021
Patterns of multimorbidity in 4588 older adults. Implications for non-geriatrician specialist.
Piotrowicz K, Pac A, Skalska A, Mossakowska M, Chudek J, Zdrojewski T, Więcek A, Grodzicki T, Gąsowski J.
Pol Arch Intern Med. 2021
Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae.
Tudek A, Krawczyk PS, Mroczek S, Tomecki R, Turtola M, Matylla-Kulińska K, Jensen TH, Dziembowski A.
Nat Commun. . 2021
Prevention of Epilepsy in Infants with Tuberous Sclerosis Complex in the EPISTOP Trial.
Kotulska K, Kwiatkowski DJ, Curatolo P, Weschke B, Riney K, Jansen F, Feucht M, Krsek P, Nabbout R, Jansen AC, Wojdan K, Sijko K, Głowacka-Walas J, Borkowska J, Sadowski K, Domańska-Pakieła D, Moavero R, Hertzberg C, Hulshof H, Scholl T, Benova B, Aronica E, de Ridder J, Lagae L, Jóźwiak S; EPISTOP Investigators (Jaworski J, Błażejczyk M, Tempes A, Urbańska M.)
Ann Neurol. 2021
Serum Uric Acid Is a Weak Independent Predictor of Overall Survival in Older Adults.
Winder M, Owczarek AJ, Mossakowska M, Holecki M, Broczek K, Grodzicki T, Zdrojewski T, Chudek J.
J Clin Med.. 2021
Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker.
Minhas R, Loeffler-Wirth H, Siddiqui YH, Obrębski T, Vashisht S, Abu Nahia K, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL.
BMC Genomics.. 2021
Two New M23 Peptidoglycan Hydrolases With Distinct Net Charge.
Wysocka A, Jagielska E, Łężniak Ł, Sabała I.
Front Microbiol.. 2021
Genomic and physiological analyses of the zebrafish atrioventricular canal reveal molecular building blocks of the secondary pacemaker region.
Abu Nahia K, Migdał M, Quinn TA, Poon KL, Łapiński M, Sulej A, Liu J, Mondal SS, Pawlak M, Bugajski Ł, Piwocka K, Brand T, Kohl P, Korzh V, Winata C.
Cell Mol Life Sci.. 2021
RNA pull-down confocal nanoscanning (RP-CONA) detects quercetin as pri-miR-7/HuR interaction inhibitor that decreases α-synuclein levels.
Zhu S, Choudhury NR, Rooney S, Pham NT, Koszela J, Kelly D, Spanos C, Rappsilber J, Auer M, Michlewski G.
Nucleic Acids Res.. 2021
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants.
NCD Risk Factor Collaboration (NCD-RisC) (Mossakowska M.)
Lancet. 2021
Causes of Anemia in Polish Older Population-Results from the PolSenior Study.
Styszyński A, Chudek J, Mossakowska M, Lewandowski K, Puzianowska-Kuźnicka M, Klich-Rączka A, Więcek A, Wieczorowska-Tobis K.
Cells. 2021
High Behavioral Variability Mediated by Altered Neuronal Excitability in auts2 Mutant Zebrafish.
Jha U, Kondrychyn I, Korzh V, Thirumalai V.
eNeuro. 2021
Cardiac-specific β-catenin deletion dysregulates energetic metabolism and mitochondrial function in perinatal cardiomyocytes.
Balatskyi VV, Vaskivskyi VO, Myronova A, Avramets D, Nahia KA, Macewicz LL, Ruban TP, Kucherenko DY, Soldatkin OO, Lushnikova IV, Skibo GG, Winata CL, Dobrzyn P, Piven OO.
Mitochondrion.. 2021
Defining a novel domain that provides an essential contribution to site-specific interaction of Rep protein with DNA.
Nucleic Acids Res.. 2021
Muscle-derived exophers promote reproductive fitness.
Turek M, Banasiak K, Piechota M, Shanmugam N, Macias M, Śliwińska MA, Niklewicz M, Kowalski K, Nowak N, Chacinska A, Pokrzywa W.
EMBO Rep.. 2021
The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion.
Zdżalik-Bielecka D, Poświata A, Kozik K, Jastrzębski K, Schink KO, Brewińska-Olchowik M, Piwocka K, Stenmark H, Miączyńska M.
Proc Natl Acad Sci USA. 2021
Distinction between self and non-self in restriction modification: The mysterious case of type IIL enzymes.
Bochtler M.
Structure. 2021
Structures of substrate complexes of foamy viral protease-reverse transcriptase.
Nowacka M, Nowak E, Czarnocki-Cieciura M, Jackiewicz J, Skowronek K, Szczepanowski R, Wöhrl BM, Nowotny M.
J Virol.. 2021
Structural Characterization of EnpAD,L-Endopeptidase from Enterococcus faecalis Prophage Provides Insights into Substrate Specificity of M23Peptidases.
Małecki PH, Mitkowski P, Jagielska E, Trochimiak K, Mesnage S, Sabała I.
. 2021
Staphylococcus aureus Specific Electrospun Wound Dressings: Influence of Immobilization Technique on Antibacterial Efficiency of Novel Enzybiotic.
Urbanek O, Wysocka A, Nakielski P, Pierini F, Jagielska E, Sabała I.
Pharmaceutics. . 2021
The development of zebrafish pancreas affected by deficiency of Hedgehog signaling.
Korzh S, Winata CL, Gong Z, Korzh V.
Gene Expr Patterns.. 2021
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Prentzell MT et al. (Jaworski J, Kedra M, Kopach A, Macias M, Zmorzynska J.)
Cell. 2021
Cytoplasmic polyadenylation by TENT5A is required for proper bone formation.
Gewartowska O, Aranaz-Novaliches G, Krawczyk PS, Mroczek S, Kusio-Kobiałka M, Tarkowski B, Spoutil F, Benada O, Kofroňová O, Szwedziak P, Cysewski D, Gruchota J, Szpila M, Chlebowski A, Sedlacek R, Prochazka J, Dziembowski A.
Cell Rep.. 2021
Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2.
Czapinska H, Winiewska-Szajewska M, Szymaniec-Rutkowska A, Piasecka A, Bochtler M, Poznański J.
J Phys Chem B.. 2021
AnnapuRNA: A scoring function for predicting RNA-small molecule binding poses.
Stefaniak F, Bujnicki JM.
PLoS Comput Biol.. 2021
RNA and DNA G-quadruplexes bind to human dicer and inhibit its activity.
Koralewska N, Szczepanska A, Ciechanowska K, Wojnicka M, Pokornowska M, Milewski MC, Gudanis D, Baranowski D, Nithin C, Bujnicki JM, Gdaniec Z, Figlerowicz M, Kurzynska-Kokorniak A.
Cell Mol Life Sci.. 2021
mTOR controls endoplasmic reticulum-Golgi apparatus trafficking of VSVg in specific cell types.
Koscielny A, Liszewska E, Machnicka K, Wezyk M, Kotulska K, Jaworski J.
Cell Mol Biol Lett.. 2021
Functions and mechanisms of RNA tailing by metazoan terminal nucleotidyltransferases.
Liudkovska V, Dziembowski A.
Wiley Interdiscip Rev RNA.. 2021
Caffeine-Cyclodextrin Complexes as Solids: Synthesis, Biological and Physicochemical Characterization.
Szmeja S, Gubica T, Ostrowski A, Zalewska A, Szeleszczuk Ł, Zawada K, Zielińska-Pisklak M, Skowronek K, Wiweger M.
Int J Mol Sci.. 2021
npc2-Deficient Zebrafish Reproduce Neurological and Inflammatory Symptoms of Niemann-Pick Type C Disease.
Wiweger M, Majewski L, Adamek-Urbanska D, Wasilewska I, Kuznicki J.
Front Cell Neurosci.. 2021
Evolutionary context can clarify gene names: Teleosts as a case study.
Gasanov EV, Jędrychowska J, Kuźnicki J, Korzh V.
BioEssays. 2021
Molecular Components of Store-Operated Calcium Channels in the Regulation of Neural Stem Cell Physiology, Neurogenesis, and the Pathology of Huntington’s Disease.
Latoszek E, Czeredys M.
Front Cell Dev Biol.. 2021
Dissecting biological activities of fibroblast growth factor receptors by the coiled-coil-mediated oligomerization of FGF1.
Porebska N, Pozniaka M, Krzyscik MA, Knapika A, Czyrek A, Kucinska M, Jastrzebski K, Zakrzewska M, Otlewski J, Opalinski L.
Int J Biol Macromol.. 2021
Prevalence and socioeconomic predictors of diagnosed and undiagnosed diabetes in oldest-old and younger Caucasian seniors: results from the PolSenior study.
Puzianowska-Kuźnicka M, Januszkiewicz-Caulier J, Kuryłowicz A, Mossakowska M, Zdrojewski T, Szybalska A, Skalska A, Chudek J, Franek E.
Endokrynol Pol.. 2021
The Dose-Dependent Pleiotropic Effects of the UBB+1 Ubiquitin Mutant.
Banasiak K, Szulc NA, Pokrzywa W.
Front. Mol. Biosci. . 2021
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight.
NCD Risk Factor Collaboration (Mossakowska M.)
eLife. . 2021
DNAmoreDB, a database of DNAzymes.
Ponce-Salvatierra A, Boccaletto P, Bujnicki JM.
Nucleic Acids Res.. 2021
Exploring Translational Control of Maternal mRNAs in Zebrafish.
Winata CL, Łapiński M, Ismail H, Mathavan S, Sampath P.
Methods Mol Biol.. 2021
Establishment of two hiPSC lines (IIMCBi001-A and IIMCBi002-A) from dermal fibroblasts of healthy donors and characterization of their cell cycle.
Liszewska E, Majchrowicz L, Krogulec E, Kotulska K, Kaczmarek L, Kalita K, Dobrzyń A, Jaworski J.
Stem Cell Res.. 2021
Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA.
Pastor M, Czapinska H, Helbrecht I, Krakowska K, Lutz T, Xu S, Bochtler M.
Nucleic Acids Res.. 2021
Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses.
Kolmus K, Erdenebat P, Szymańska E, Stewig B, Goryca K, Derezinska-Wolek E, Szumera-Cieckiewicz A, Brewinska-Olchowik M, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miaczynska M.
J Cell Sci.. 2021
Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect.
Warminski M, Kowalska J, Nowak E, Kubacka D, Tibble R, Kasprzyk R, Sikorski PJ, Gross JD, Nowotny M, Jemielity J.
ACS Chem Biol.. 2021
Prevalence of Hyperuricemia and the Use of Allopurinol in Older Poles-Results from a Population-Based PolSenior Study.
Winder M, Owczarek AJ, Mossakowska M, Broczek K, Grodzicki T, Wierucki Ł, Chudek J.
Int J Environ Res Public Health.. 2021
Kcnb1 plays a role in development of the inner ear.
Jedrychowska J, Gasanov EV, Korzh V.
Dev Biol.. 2021
An improved method for precise genome editing in zebrafish using CRISPR-Cas9 technique.
Gasanov EV, Jędrychowska J, Pastor M, Wiweger M, Methner A, Korzh VP.
Mol Biol Rep.. 2021
DNA adenine methylation in eukaryotes: Enzymatic mark or a form of DNA damage?
Bochtler M, Fernandes H.
BioEssays. 2021
Cell-type-specific insights into iron regulatory processes.
Mleczko-Sanecka K, Silvestri L.
Am J Hematol.. 2021
Camel regulates development of the brain ventricular system.
Yang S, Emelyanov A, You MS, Sin M, Korzh V.
Cell Tissue Res.. 2021
Recent advances in user-friendly computational tools to engineer protein function.
Sequeiros-Borja CE, Surpeta B, Brezovsky J.
Briefings in Bioinformatics. 2021
2020
Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements.
Manfredonia I, Nithin C, Ponce-Salvatierra A, Ghosh P, Wirecki TK, Marinus T, Ogando NS, Snijder EJ, van Hemert MJ, Bujnicki JM, Incarnato D.
Nucleic Acids Res. 2020
Health status and its socio-economic covariates in the older population in Poland - the assumptions and methods of the nationwide, cross-sectional PolSenior2 survey.
Wierucki Ł, Kujawska-Danecka H, Mossakowska M, Grodzicki T, Błędowski P, Chudek J, Kostka T, Więcek A, Hajduk A, Bandosz P, Zagożdżon P, Wojtyniak B, Zdrojewski T.
Arch Med Sci.. 2020
Luciferase reporter assay for small-molecule inhibitors of MIR92b-3p function: Screening cyanopeptolins produced by Nostoc from the Baltic Sea.
Brzuzan P, Mazur-Marzec H, Florczyk M, Stefaniak F, Fidor A, Konkel R, Woźny M.
Toxicol In Vitro.. 2020
Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase.
Andryianau G, Kowalski M, Piotrowicz MC, Rajkiewicz AA, Dymek B, Sklepkiewicz PL, Pluta E, Stefaniak F, Czestkowski W, Olejniczak S, Mazur M, Niedziejko P, Koralewski R, Matyszewski K, Gruza M, Zagozdzon A, Salamon M, Rymaszewska A, Welzer M, Dzwonek K, Golab J, Olczak J, Bartoszewicz A, Golebiowski A.
ACS Med Chem Lett.. 2020
Blood Lipids and Cognitive Performance of Aging Polish Adults: A Case-Control Study Based on the PolSenior Project.
McFarlane O, Kozakiewicz M, Kędziora-Kornatowska K, Gębka D, Szybalska A, Szwed M, Klich-Rączka A.
Front Aging Neurosci.. 2020
β-Catenin Regulates Cardiac Energy Metabolism in Sedentary and Trained Mice.
Balatskyi VV, Palchevska OL, Bortnichuk L, Gan AM, Myronova A, Macewicz LL, Navrulin VO, Tumanovska LV, Olichwier A, Dobrzyn P, Piven OO.
Life (Basel). 2020
The zebrafish as a model for developmental and biomedical research in Poland and beyond.
Winata CL, Dodzian J, Bialek-Wyrzykowska U.
Dev Biol.. 2020
The expression of Rpb10, a small subunit common to RNA polymerases, is modulated by the R3H domain-containing Rbs1 protein and the Upf1 helicase.
Cieśla M, Turowski TW, Nowotny M, Tollervey D, Boguta M.
Nucleic Acids Res.. 2020
Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.
Koralewski R, Dymek B, Mazur M, Sklepkiewicz P, Olejniczak S, Czestkowski W, Matyszewski K, Andryianau G, Niedziejko P, Kowalski M, Gruza M, Borek B, Jedrzejczak K, Bartoszewicz A, Pluta E, Rymaszewska A, Kania M, Rejczak T, Piasecka S, Mlacki M, Mazurkiewicz M, Piotrowicz M, Salamon M, Zagozdzon A, Napiorkowska-Gromadzka A, Bartlomiejczak A, Mozga W, Dobrzański P, Dzwonek K, Golab J, Nowotny M, Olczak J, Golebiowski A.
J Med Chem.. 2020
Disulfide bridge cross-linking between protein and the RNA backbone as a tool to study RNase H1.
Hyjek-Składanowska M, Stasińska AR, Napiórkowska-Gromadzka A, Bartłomiejczak A, Seth PP, Chmielewski MK, Nowotny M.
Bioorg Med Chem. . 2020
Evolutionary History and Activity of RNase H1-Like Proteins in Arabidopsis thaliana.
Kuciński J, Chamera S, Kmera A, Rowley MJ, Fujii S, Khurana P, Nowotny M, Wierzbicki AT.
Plant Cell Physiol.. 2020
Facultative Parthenogenesis in a Diamondback Water Snake (Nerodia rhombifer).
Gasanov EV, Katz AV.
Russ J Herpetol.. 2020
BDNF Val66Met Polymorphism, the Allele-Specific Analysis by qRT-PCR - a Novel Protocol.
de Assis GG, Hoffman JR, Gasanov EV.
Int J Med Sci.. 2020
Respiratory Syndrome Coronavirus Infections: Possible Mechanisms of Neurological Implications-A Systematic Review.
de Assis GG, Murawska-Cialowicz E, Cieszczyk P, Gasanov EV.
Front Neurol.. 2020
Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions.
Veerapathiran S, Teh C, Zhu S, Kartigayen I, Korzh V, Matsudaira PT, Wohland T.
eLife. 2020
Dysregulation of Neuronal Calcium Signaling via Store-Operated Channels in Huntington’s Disease.
Czeredys M.
Front Cell Dev Biol.. 2020
Clathrin- and dynamin-dependent endocytosis limits canonical NF-κB signaling triggered by lymphotoxin β receptor.
Maksymowicz M, Miączyńska M, Banach-Orłowska M.
Cell Commun Signal.. 2020
Pathogenic Variants in the Myosin Chaperone UNC-45B Cause Progressive Myopathy with Eccentric Cores.
Donkervoort S, Kutzner CE, Hu Y, Lornage X, Rendu J, Stojkovic T, Baets J, Neuhaus SB, Tanboon J, Maroofian R, Bolduc V, Mroczek M, Conijn S, Kuntz NL, Töpf A, Monges S, Lubieniecki F, McCarty RM, Chao KR, Governali S, Böhm J, Boonyapisit K, Malfatti E, Sangruchi T, Horkayne-Szakaly I, Hedberg-Oldfors C, Efthymiou S, Noguchi S, Djeddi S, Iida A, di Rosa G, Fiorillo C, Salpietro V, Darin N, Faure´ J, Houlden H, Oldfors A, Nishino I, de Ridder W, Straub V, Pokrzywa W, Laporte J, Foley R, Romero NB, Ottenheijm C, Hoppe T, Bönnemann CG.
Am. J. Hum. Genet.. 2020
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants.
NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M & Slusarczyk P.
Lancet. 2020
Age-related differences in vitamin D status in Polish centenarians compared with 65-year-olds.
Kupisz-Urbańska M, Broczek K, Galus K, Mossakowska M, Marcinowska-Suchowierska E.
Pol Arch Intern Med. 2020
Splicing variants of an endocytic regulator, BMP2K, differentially control autophagic degradation in erythroid cells.
Autophagy. 2020
Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine..
Nucleic Acids Res.. 2020
HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells.
Cancers (Basel). 2020
Productivity Loss Among Parents of Children With Inflammatory Bowel Diseases in Relation to Disease Activity and Patient's Quality of Life.
Stawowczyk E, Kawalec P, Kowalska-Duplaga K, Mossakowska M.
J Pediatr Gastroenterol Nutr.. 2020
CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage.
Albert M-C, Brinkmann K, Pokrzywa W, Günther SD, Krönke M, Hoppe T, Kashkar H.
Cell Death & Disease. 2020
Knockout of stim2a Increases Calcium Oscillations in Neurons and Induces Hyperactive-Like Phenotype in Zebrafish Larvae.
Gupta RK, Wasilewska I, Palchevska O, Kuźnicki J.
Int. J. Mol. Sci.. 2020
Targeted RNA Knockdown by a Type III CRISPR-Cas Complex in Zebrafish.
Fricke T, Smalakyte D, Lapinski M, Pateria A, Weige C, Pastor M, Kolano A, Winata C, Siksnys V, Tamulaitis G, Bochtler M.
CRISPR J.. 2020
Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells.
Cendrowski J, Kaczmarek M, Mazur M, Kuzmicz-Kowalska K, Jastrzebski K, Brewinska-Olchowik M, Kominek A, Piwocka K, Miaczynska M.
eLife . 2020
Protein Domain Guided Screen for Sequence Specific and Phosphorothioate-Dependent Restriction Endonucleases.
Lutz T, Czapinska H, Fomenkov A, Potapov V, Heiter DF, Cao B, Dedon P, Bochtler M, Xu S.
Front. Microbiol.. 2020
RNAProbe: a web server for normalization and analysis of RNA structure probing data.
Wirecki TK, Merdas K, Bernat A, Boniecki MJ, Bujnicki JM, Stefaniak F.
Nucleic Acids Res. . 2020
TSC2 pathogenic variants are predictive of severe clinical manifestations in TSC infants: results of the EPISTOP study.
Ogórek B, Hamieh L, Hulshof HM, Lasseter K, Klonowska K, Kuijf H, Moavero R, Hertzberg C, Weschke B, Riney K, Feucht M, Scholl T, Krsek P, Nabbout R, Jansen AC, Benova B, Aronica E, Lagae L, Curatolo P, Borkowska J, Sadowski K, Domańska-Pakieła D, Janson S, Kozlowski P, Urbanska M, Jaworski J, Jozwiak S, Jansen FE, Kotulska K; EPISTOP Consortium members, Kwiatkowski DJ.
Genet Med. . 2020
IQGAP1-dysfunction leads to induction of senescence in human vascular smooth muscle cells.
Grabowska W, Achtabowska N, Klejman A, Skowronek K, Calka M, Bielak-Zmijewska A.
Mech Ageing Dev.. 2020
Zebrafish Microenvironment Elevates EMT and CSC-Like Phenotype of Engrafted Prostate Cancer Cells.
Chen L, Olszewski MB, Kruithof-de MJ, Snaar-Jagalska BE.
Cells. 2020
Origin and development of circumventricular organs in living vertebrate.
Korzh V, Kondrychyn I.
Semin Cell Dev Biol.. 2020
Mitochondrial protein biogenesis in the synapse is supported by local translation.
Kuzniewska B, Cysewski D, Wasilewski M, Sakowska P, Milek J, Kulinski TM, Winiarski M, Kozielewicz P, Knapska E, Dadlez M, Chacinska A, Dziembowski A, Dziembowska M.
EMBO Rep.. 2020
Biological and Medical Importance of Cellular Heterogeneity Deciphered by Single-Cell RNA Sequencing.
Gupta RK, Kuznicki J.
Cells. 2020
Repositioning of the global epicentre of non-optimal cholesterol.
NCD Risk Factor Collaboration (Mossakowska M and Ślusarczyk P)
Nature. 2020
Nutritional status and fecundity are synchronised by muscular exopheresis.
Turek M, Piechota M, Shanmugam N, Niklewicz M, Kowalski K, Chacińska A, Pokrzywa W.
bioRxiv. 2020
stim2b Knockout Induces Hyperactivity and Susceptibility to Seizures in Zebrafish Larvae.
Wasilewska I, Gupta RK, Wojtaś B, Palchevska O, Kuźnicki J.
Cells. 2020
The effects of temperature on the proxies of visual detection of Danio rerio larvae: observations from the optic tectum.
Babkiewicz E, Bazała M, Urban P, Maszczyk P, Markowska M, Gliwicz M.
Biology Open . 2020
FGFR1 Clustering With Engineered Tetravalent Antibody Improves the Efficiency and Modifies the Mechanism of Receptor Internalization.
Pozniak M, Sokolowska-Wedzina A, Jastrzebski K, Szymczyk J, Porebska N, Krzyscik MA, Zakrzewska M, Miaczynska M, Otlewski J, Opalinski L.
Mol Oncol. . 2020
National Trends in Total Cholesterol Obscure Heterogeneous Changes in HDL and non-HDL Cholesterol and total-to-HDL Cholesterol Ratio: A Pooled Analysis of 458 Population-Based Studies in Asian and Western Countries.
NCD Risk Factor Collaboration (Mossakowska M and Ślusarczyk P)
Int J Epidemiol.. 2020
Targeting mitochondrial calcium pathways as a potential treatment against Parkinson’s disease.
Dey K, Bazala MA, Kuznicki J.
Cell Calcium. 2020
Restriction endonucleases that cleave RNA/DNAheteroduplexes bind dsDNA in A-like conformation.
Kisiala M, Kowalska M, Pastor M, Korza HJ, Czapinska H, Bochtler M.
Nucleic Acids Res.. 2020
The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells.
Fatima A, Irmak D, Noormohammadi A, Rinschen MM, Das A, Leidecker O, Schindler C, Sánchez-Gaya V, Wagle P, Pokrzywa W, Hoppe T, Rada-Iglesias A, Vilchez D.
Commun Biol.. 2020
In Vitro Directed Evolution of a Restriction Endonuclease With More Stringent Specificity.
Skowronek KJ, Bochtler M.
J Vis Exp . 2020
RNA-Puzzles Round IV: 3D Structure Predictions of Four Ribozymes and Two Aptamers.
Miao Z et al. (Boniecki MJ, Bujnicki JM, Joshi A, Magnus M, Piatkowski P, Pluta R.)
RNA. 2020
MetaPhOrs 2.0: Integrative, Phylogeny-Based Inference of Orthology and Paralogy Across the Tree of Life.
Chorostecki U, Molina M, Pryszcz LP, Gabaldón T.
Nucleic Acids Res.. 2020
Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition.
Lambert AR, Hallinan JP, Werther R, Głów D, Stoddard BL.
Structure. 2020
Immunoglobulin Expression and the Humoral Immune Response Is Regulated by the Non-Canonical poly(A) Polymerase TENT5C.
Bilska A, Kusio-Kobiałka M, Krawczyk PS, Gewartowska O, Tarkowski B, Kobyłecki K, Nowis D, Golab J, Gruchota J, Borsuk E, Dziembowski A, Mroczek S.
Nat Commun.. 2020
Vimentin S-glutathionylation at Cys328 Inhibits Filament Elongation and Induces Severing of Mature Filaments in Vitro.
Kaus-Drobek M, Mücke N, Szczepanowski RH, Wedig T, Czarnocki-Cieciura M, Polakowska M, Herrmann H, Wysłouch-Cieszyńska A, Dadlez M.
FEBS J.. 2020
Human REXO2 Controls Short Mitochondrial RNAs Generated by mtRNA Processing and Decay Machinery to Prevent Accumulation of Double-Stranded RNA.
Szewczyk M, Malik D, Borowski LS, Czarnomska SD, Kotrys AV, Klosowska-Kosicka K, Nowotny M, Szczesny RJ.
Nucleic Acids Res.. 2020
MasterOfPores: A Workflow for the Analysis of Oxford Nanopore Direct RNA Sequencing Datasets
Cozzuto L, Liu H, Pryszcz LP, Pulido TH, Delgado-Tejedor A, Ponomarenko J, Novoa EM.
Front Genet.. 2020
Dynamics, a Powerful Component of Current and Future in Silico Approaches for Protein Design and Engineering.
Surpeta B, Sequeiros-Borja CE, Brezovsky J.
Int J Mol Sci.. 2020
Origins of the increased affinity of phosphorothioate-modified therapeutic nucleic acids for proteins.
Hyjek-Składanowska M, Vickers T, Napiórkowska A, Anderson B, Tanowitz M, Crooke ST, Liang XH, Seth PP, Nowotny M.
J Am Chem Soc.. 2020
miR-7 Controls the Dopaminergic/Oligodendroglial Fate through Wnt/β-catenin Signaling Regulation.
Adusumilli L, Facchinello N, Teh C, Busolin G, Le MT, Yang H, Beffagna G, Campanaro S, Tam WL, Argenton F, Lim B, Korzh V, Tiso N.
Cells . 2020
First Evidence for STING SNP R293Q Being Protective Regarding Obesity-Associated Cardiovascular Disease in Age-Advanced Subjects - A Cohort Study.
Hamann L, Szwed M, Mossakowska M, Chudek J, Puzianowska-Kuznicka M.
Immun Ageing . 2020
Role of dynein-dynactin complex, kinesins, motor adaptors and their phosphorylation in dendritogenesis.
Tempes A, Weslawski J, Brzozowska A, Jaworski J.
J Neurochem.. 2020
RNA-Puzzles toolkit: a computational resource of RNA 3D structure benchmark datasets, structure manipulation, and evaluation tools.
Magnus M, Antczak M, Zok T, Wiedemann J, Lukasiak P, Cao Y, Bujnicki JM, Westhof E, Szachniuk M, Miao Z.
Nucleic Acids Res.. 2020
Membrane Trafficking: Vesicle Formation, Cargo Sorting and Fusion.
Miaczynska M, Munson M.
Mol Biol Cell. . 2020
TrkB hyperactivity contributes to brain dysconnectivity, epileptogenesis, and anxiety in zebrafish model of Tuberous Sclerosis Complex.
Kedra M, Banasiak K, Kisielewska K, Wolinska-Niziol L, Jaworski J, Zmorzynska J.
Proc Natl Acad Sci U S A. . 2020
Article BioShell 3.0: Library for Processing Structural Biology Data.
Macnar JM, Szulc N, Kryś JD, Badaczewska-Dawid AE, Gront D.
Biomolecules. 2020
Transgenic Mice Overexpressing Human STIM2 and ORAI1 in Neurons Exhibit Changes in Behavior and Calcium Homeostasis but Show No Signs of Neurodegeneration.
Majewski L, Maciąg F, Boguszewski PM, Kuznicki J.
Int. J. Mol. Sci.. 2020
STIM Protein-NMDA2 Receptor Interaction Decreases NMDA-Dependent Calcium Levels in Cortical Neurons.
Gruszczynska-Biegala J, Strucinska K, Maciag F, Majewski L, Sladowska M, Kuznicki J.
Cells. 2020
Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer.
Szymańska E, Nowak P, Kolmus K, Cybulska M, Goryca K, Derezińska-Wołek E, Szumera-Ciećkiewicz A, Brewińska-Olchowik M, Grochowska A, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miączyńska M.
EMBO Mol Med.. 2020
A combined structural and biochemical approach reveals translocation and stalling of UvrB on the DNA lesion as a mechanism of damage verification in bacterial nucleotide excision repair.
Jaciuk M, Swuec P, Gaur V, Kasprzak JM, Renault L, Dobrychłop M, Nirwal S, Bujnicki JM, Costa A, Nowotny M.
DNA Repair (Amst).. 2020
Ubiquitin Signaling Regulates RNA Biogenesis, Processing, and Metabolism.
Thapa P, Shanmugam N, Pokrzywa W.
BioEssays. 2020
Two-site recognition of Staphylococcus aureus peptidoglycan by lysostaphin SH3b.
Gonzalez-Delgado LS, Walters-Morgan H, Salamaga B, Robertson AJ, Hounslow AM, Jagielska E, Sabała I, Williamson MP, Lovering AL, Mesnage S.
Nat Chem Biol.. 2020
2019
Crosslink and shield: protecting abasic sites from error-prone repair.
Nowotny M.
Nat Struct Mol Biol.. 2019
Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7.
Mohanraj K, Wasilewski M, Benincá C, Cysewski D, Poznanski J, Sakowska P, Bugajska Z, Deckers M, Dennerlein S, Fernandez-Vizarra E, Rehling P, Dadlez M, Zeviani M, Chacinska A.
EMBO Mol Med.. 2019
Non-canonical translation initiation in yeast generates a cryptic pool of mitochondrial proteins.
Monteuuis G, Miścicka A, Świrski M, Zenad L, Niemitalo O, Wrobel L, Alam J, Chacinska A, Kastaniotis AJ, Kufel J.
Nucleic Acids Res.. 2019
The protein-binding N-terminal domain of human translation elongation factor 1Bβ possesses a dynamic α-helical structural organization.
Bondarchuk TV, Lozhko DM, Shalak VF, Fatalska A, Szczepanowski RH, Dadlez M,
Negrutskii BS, El'skaya AV.
Int J Biol Macromol. . 2019
Enhanced oligomerization of full-length RAGE by synergy of the interaction of its domains.
Moysa A, Hammerschmid D, Szczepanowski RH, Sobott F, Dadlez M.
Sci Rep. . 2019
Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases.
Mazur M, Dymek B, Koralewski R, Sklepkiewicz P, Olejniczak S, Mazurkiewicz M, Piotrowicz M, Salamon M, Jędrzejczak K, Zagozdzon A, Czestkowski W, Matyszewski K, Borek B, Bartoszewicz A, Pluta E, Rymaszewska A, Mozga W, Stefaniak F, Dobrzański P, Dzwonek K, Golab J, Golebiowski A, Olczak J.
J Med Chem. . 2019
Improving selectivity of DNA-RNA binding zinc finger using directed evolution.
Sulej AA
BMC Res Notes. . 2019
RRMdb – an evolutionary-oriented database of RNA recognition motif sequences.
Nowacka M, Boccaletto P, Jankowska E, Jarzynka T, Bujnicki JM, Dunin-Horkawicz S.
Database. 2019
Matching tRNA modifications in humans to their known and predicted enzymes.
de Crecy-Lagard V, Boccaletto P, Mangleburg C, Sharma P, Lowe T, Leidel S, Bujnicki JM.
Nucleic Acids Res.. 2019
QRNAS: software tool for refinement of nucleic acid structures.
Stasiewicz J, Mukherjee S, Nithin C, Bujnicki JM.
BMC Struct Biol. . 2019
RNAcentral: a hub of information for non-coding RNA sequences.
The RNAcentral Consortium (Bujnicki JM, Boccaletto P)
Nucleic Acids Res. . 2019
Parathyroid hormone response to different vitamin D levels in population-based old and very-old Polish cohorts.
Wyskida M, Owczarek AJ, Chełmecka E, Szczerbowska I, Mossakowska M, Grodzicki T, Puzianowska-Kuźnicka M, Olszanecka-Glinianowicz M, Chudek J.
Exp Gerontol.. 2019
Cholesterol restricts lymphotoxin β receptor-triggered NF-κB signaling.
Banach-Orłowska M, Wyszyńska R, Pyrzyńska B, Maksymowicz M, Gołąb J, Miączyńska M.
Cell Commun Signal.. 2019
Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Slyvka A, Zagorskaitė E, Czapinska H, Sasnauskas G, Bochtler M.
Nucleic Acids Res.. 2019
Petri net-based model of the human DNA base excision repair pathway.
Radom M, Machnicka MA, Krwawicz J, Bujnicki JM, Formanowicz P
PLoS One. 2019
RNA 3D structure prediction guided by independent folding of homologous sequences.
Magnus M, Kappel K, Das R, Bujnicki JM
BMC Bioinformatics. 2019
Changes in Calcium Homeostasis and Gene Expression Implicated in Epilepsy in Hippocampi of Mice Overexpressing ORAI1.
Majewski L, Wojtas B, Maciąg F, Kuznicki J.
Int J Mol Sci. . 2019
Influence of Sociodemographic, Behavioral and Other Health-Related Factors on Healthy Ageing Based on Three Operative Definitions.
Pac A, Tobiasz-Adamczyk B, Błędowski P, Skalska A, Szybalska A, Zdrojewski T, Więcek A, Chudek J, Michel JP, Grodzicki T.
J Nutr Health Aging.. 2019
Obesity Paradox in Caucasian Seniors: Results of the PolSenior Study.
Puzianowska-Kuznicka M, Kuryłowicz A, Walkiewicz D, Borkowska J, Owczarz M, Olszanecka-Glinianowicz M, Wieczorowska-Tobis K, Skalska A, Szybalska A, Mossakowska M.
J Nutr Health Aging. . 2019
Restriction of mitochondrial calcium overload by mcu inactivation renders neuroprotective effect in Zebrafish models of Parkinson's disease.
Soman SK, Bazała M, Keatinge M, Bandmann O, Kuznicki J.
Biol Open.. 2019
Kv2.1 voltage‐gated potassium channels in developmental perspective.
Jędrychowska J, Korzh V.
Dev Dyn.. 2019
Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease.
Gaur V, Ziajko W, Nirwal S, Szlachcic A, Gapińska M, Nowotny M
Nucleic Acids Res.. 2019
RuvC uses dynamic probing of the Holliday junction substrate to achieve sequence specificity and efficient resolution.
Górecka KM, Krepl M, Szlachcic A, Poznański J, Šponer J, Nowotny M.
Nat Commun.. 2019
A protein architecture guided screen for modification dependent restriction endonucleases.
Lutz T, Flodman K, Copelas A, Czapinska H, Mabuchi M, Fomenkov A, He X, Bochtler M, Xu S.
Nucleic Acids Res.. 2019
Glomerular permeability is not affected by heparan sulfate glycosaminoglycan deficiency in zebrafish embryos.
Khalil R, Lalai RA, Wiweger MI, Avramut CM, Koster AJ, Spaink HP, Bruijn JA, Hogendoorn PCW, Baelde HJ.
Am J Physiol Renal Physiol.. 2019
CA125 as a Marker of Heart Failure in the Older Women: Population-Based Analysis.
Bulska-Będkowska W, Chełmecka E, Owczarek AJ, Mizia-Stec K, Witek A, Szybalska A, Grodzicki T, Olszanecka-Glinianowicz M, Chudek J.
J Clin Med. 2019
Clinical examination of peripheral arterial disease and ankle-brachial index in a nationwide cohort of older subjects: practical implications.
Królczyk J, Piotrowicz K, Chudek J, Puzianowska-Kuźnicka M, Mossakowska M, Szybalska A, Grodzicki T, Skalska A, Gąsowski J.
Aging Clin Exp Res. 2019
A novel conserved enhancer at zebrafish zic3 and zic6 loci drives neural expression.
Minhas R, Paterek A, Łapiński M, Bazała M, Korzh V, Winata CL
Dev Dyn. . 2019
Rising rural body-mass index is the main driver of the global obesity epidemic in adults.
NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M and Ślusarczyk P
Nature. 2019
Heat shock proteins create a signature to predict the clinical outcome in breast cancer.
Klimczak M, Biecek P, Zylicz A, Zylicz M.
Sci Rep. . 2019
Cytosolic translational responses differ under conditions of severe short-term and long-term mitochondrial stress.
Samluk L, Urbanska M, Kisielewska K, Mohanraj K, Kim MJ, Machnicka K, Liszewska E, Jaworski J, Chacinska A.
Mol Biol Cell.. 2019
Specific interaction of zinc finger protein Com with RNA and the crystal structure of a self-complementary RNA duplex recognized by Com.
Nowacka M, Fernandes H, Kiliszek A, Bernat A, Lach G, Bujnicki JM.
PLoS One. 2019
DNA polymerase ι is acetylated in response to SN2 alkylating agents.
McIntyre J, Sobolewska A, Fedorowicz M, McLenigan MP, Macias M, Woodgate R, Sledziewska-Gojska E.
Sci Rep.. 2019
Crystal Structure and Directed Evolution of Specificity of NlaIV Restriction Endonuclease.
Czapinska H, Siwek W, Szczepanowski RH, Bujnicki JM, Bochtler M, Skowronek KJ.
J Mol Biol.. 2019
Identification of Zebrafish Calcium Toolkit Genes and their Expression in the Brain.
Wasilewska I, Gupta RK, Palchevska O, Kuźnicki J.
Genes (Basel). 2019
Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice.
Rojek KO, Krzemień J, Doleżyczek H, Boguszewski PM, Kaczmarek L, Konopka W, Rylski M, Jaworski J, Holmgren L, Prószyński TJ.
PLoS Biol.. 2019
Structural bases of peptidoglycan recognition by lysostaphin SH3b domain.
Mitkowski P, Jagielska E, Nowak E, Bujnicki JM, Stefaniak F, Niedziałek D, Bochtler M, Sabała I.
Sci Rep.. 2019
Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.
Ahuja G et al. (Dodzian J)
EMBO Rep.. 2019
Pathological mTOR mutations impact cortical development.
Tarkowski B, Kuchcinska K, Blazejczyk M, Jaworski J.
Hum Mol Genet.. 2019
Use of renal risk drugs in a nation-wide Polish older adult population: an analysis of PolSenior database.
Deskur-Śmielecka E, Chudek J, Neumann-Podczaska A, Mossakowska M, Wizner B, Wieczorowska-Tobis K.
BMC Geriatr. . 2019
Interplay of Chimeric Mating-Type Loci Impairs Fertility Rescue and Accounts for Intra-Strain Variability in Zygosaccharomyces rouxii Interspecies Hybrid ATCC42981.
Bizzarri M, Cassanelli S, Bartolini L, Pryszcz LP, Dušková M, Sychrová H, Solieri L.
Front Genet.. 2019
Comparative transcriptome analysis reveals new molecular pathways for cucumber genes related to sex determination.
Pawełkowicz M, Pryszcz L, Skarzyńska A, Wóycicki RK, Posyniak K, Rymuszka J, Przybecki Z, Pląder W.
Plant Reprod. . 2019
Function, evolution, and structure of J-domain proteins.
Kampingaa HH et al. …. (Zylicz A, Zylicz M)
Cell Stress Chaperones.. 2019
Diverse and cancer type‑specific roles of the p53 R248Q gain‑of‑function mutation in cancer migration and invasiveness.
Olszewski MB, Pruszko M, Snaar-Jagalska E, Zylicz A, Zylicz M.
Int. J. Oncol.. 2019
Glucocorticoid receptor (NR3C1) gene polymorphisms are associated with age and blood parameters in Polish Caucasian nonagenarians and centenarians.
Olczak E, Kuryłowicz A, Wicik Z, Kołodziej P, Cąkała-Jakimowicz M, Buyanovskaya O, Ślusarczyk P, Mossakowska M, Puzianowska-Kuźnicka M.
Exp Gerontol. . 2019
Dynamics of cardiomyocyte transcriptome and chromatin landscape demarcates key events of heart development.
Pawlak M, Kedzierska KZ, Migdal M, Nahia KA, Ramilowski JA, Bugajski L, Hashimoto K, Marconi A, Piwocka K, Carninci P, Winata CL.
Genome Res.. 2019
Behavioral and electrophysiological changes in female mice overexpressing ORAI1 in neurons.
Maciąg F, Majewski Ł, Boguszewski P.M, Gupta R.K, Wasilewska I, Wojtas B, Kuznicki J.
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2019
Computational modeling of RNA 3D structure based on experimental data.
Ponce-Salvatierra A, Astha, Merdas K, Chandran N, Ghosh P, Mukherjee S, Bujnicki JM.
Biosci Rep. . 2019
GSK3β activity alleviates epileptogenesis and limits GluA1 phosphorylation.
Urbanska M, Kazmierska-Grebowska P, Kowalczyk T., Caban B, Nader K, Pijet B, Kalita K, Gozdz A, Devijvere H, Lechate B, Jaworski T, Grajkowska W, Sadowski K, Jozwiak S, Kotulska K, Konopacki J, Van Leuven F, van Vlieth E, Aronica E, Jaworski J.
EBioMedicine. 2019
Polyelectrolyte Membrane Scaffold Sustains Growth of Neuronal Cells.
Grzeczkowicz A, Gruszczynska-Biegala J, Czeredys M, Kwiatkowska A, Strawski M, Szklarczyk M, Koźbiał M, Kuźnicki J, Granicka LH.
J Biomed Mater Res A.. 2019
STING SNP R293Q Is Associated with a Decreased Risk of Aging-Related Diseases.
Hamann L, Ruiz-Moreno JS, Szwed M, Mossakowska M, Lundvall L, Schumann RR, Opitz B, Puzianowska-Kuznicka M.
Gerontology.. 2019
ESCRT Proteins Control the Dendritic Morphology of Developing and Mature Hippocampal Neurons.
Firkowska M, Macias M, Jaworski J.
Mol Neurobiol.. 2019
Novel calcineurin A (PPP3CA) variant associated with epilepsy, constitutive enzyme activation and downregulation of protein expression.
Rydzanicz M, Wachowska M, Cook EC, Lisowski P, Kuźniewska B, Szymańska K, Diecke S, Prigione A, Szczałuba K, Szybińska A, Koppolu A, Murcia Pienkowski V, Kosińska J, Wiweger M, Kostrzewa G, Brzozowska M, Domańska-Pakieła D, Jurkiewicz E, Stawiński P, Gromadka A, Zielenkiewicz P, Demkow U, Dziembowska M, Kuźnicki J, Creamer TP, Płoski R.
Eur J Hum Genet.. 2019
2018
Draft Genome Sequences of the Highly Halotolerant Strain Zygosaccharomyces rouxii ATCC 42981 and the Novel Allodiploid Strain Zygosaccharomyces sapae ATB301T Obtained Using the MinION Platform.
Bizzarri M, Cassanelli S, Pryszcz LP, Gawor J, Gromadka R, Solieri L.
Microbiol Resour Announc.. 2018
nextPARS: parallel probing of RNA structures in Illumina.
Saus E, Willis JR, Pryszcz LP, Hafez A, Llorens C, Himmelbauer H, Gabaldón T.
RNA. 2018
Transcriptome Analyses of Mosaic (MSC) Mitochondrial Mutants of Cucumber in a Highly Inbred Nuclear Background.
Mróz TL, Eves-van den Akker S, Bernat A, Skarzyńska A, Pryszcz L, Olberg M, Havey MJ, Bartoszewski G.
G3 . 2018
Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase.
Figiel M, Krepl M, Park S, Poznański J, Skowronek K, Gołąb A, Ha T, Šponer J, Nowotny M.
J Biol Chem. 2018
Integration of the Endocytic System into the Network of Cellular Functions.
Budick-Harmelin N, Miaczynska M.
Prog Mol Subcell Biol.. 2018
Brain derived neutrophic factor, a link of aerobic metabolism to neuroplasticity.
De Assis GG, Gasanov EV, de Sousa MBC, Kozacz A, Murawska-Cialowicz E. Brain derived neutrophic factor, a link of aerobic metabolism to neuroplasticity.
J Physiol Pharmacol. . 2018
Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional Aβ deposition rate and plaque burden at treatment initiation.
Brendel M, Jaworska A, Overhoff F, Blume T, Probst F, Gildehaus FJ, Bartenstein P, Haass C, Bohrmann B, Herms J, Willem M, Rominger A.
Theranostics. 2018
The level of microRNA 21 is upregulated by rapamycin in serum of tuberous sclerosis complex patients and subependymal giant cell astrocytoma (SEGA)-derived cell cultures.
Kuzniewska B, Sadowski K, Urbanska K, Urbanska M, Kotulska K, Liszewska E, Grajkowska W, Jóźwiak S, Dziembowska M.
Folia Neuropathol. . 2018
Neural Stem Cell Dysfunction in Human Brain Disorders.
Liszewska E, Jaworski J.
Results Probl Cell Differ.. 2018
c-Fos and neuronal plasticity: the aftermath of Kaczmarek's theory.
Jaworski J, Kalita K, Knapska E.
Acta Neurobiol Exp (Wars). . 2018
Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase.
Mazur M, Bartoszewicz A, Dymek B, Salamon M, Andryianau G, Kowalski M, Olejniczak S, Matyszewski K, Pluta E, Borek B, Stefaniak F, Zagozdzon A, Mazurkiewicz M, Koralewski R, Czestkowski W, Piotrowicz M, Niedziejko P, Gruza MM, Dzwonek K, Golebiowski A, Golab J, Olczak J.
28(3). 2018
Shifting meiotic to mitotic spindle assembly in oocytes disrupts chromosome alignment.
Bennabi I, Quéguiner I, Kolano A, Boudier T, Mailly P, Verlhac MH, Terret ME.
EMBO Rep.. 2018
The Bacteroidetes Q-Rule: Pyroglutamate in Signal Peptidase I Substrates.
Bochtler M, Mizgalska D, Veillard F, Nowak ML, Houston J, Veith P, Reynolds EC, Potempa J.
Front Microbiol.. 2018
The OB-fold proteins of the Trypanosoma brucei editosome execute RNA-chaperone activity.
Voigt C, Dobrychlop M, Kruse E, Czerwoniec A, Kasprzak JM, Bytner P, Campo CD, Leeder WM, Bujnicki JM, Göringer HU.
Nucleic Acids Res.. 2018
Positioning Europe for the EPITRANSCRIPTOMICS challenge.
Jantsch MF et al. (Bujnicki J, Purta E)
RNA Biol.. 2018
Human RNA cap1 methyltransferase CMTr1 cooperates with RNA helicase DHX15 to modify RNAs with highly structured 5' termini.
Toczydlowska-Socha D, Zielinska MM, Kurkowska M, Astha, Almeida CF, Stefaniak F, Purta E, Bujnicki JM.
Philos Trans R Soc Lond B Biol Sci.. 2018
Phosphoproteomic insights into processes influenced by the kinase-like protein DIA1/C3orf58.
Hareza A, Bakun M, Świderska B, Dudkiewicz M, Koscielny A, Bajur A, Jaworski J, Dadlez M, Pawłowski K.
PeerJ.. 2018
Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish.
Sokol AM, Uszczynska-Ratajczak B, Collins MM, Bazala M, Topf U, Lundegaard PR, Sugunan S, Guenther S, Kuenne C, Graumann J, Chan SSL, Stainier DYR, Chacinska A.
PLoS Genet.. 2018
Unique mechanism of target recognition by PfoI restriction endonuclease of the CCGG-family.
Tamulaitiene G, Manakova E, Jovaisaite V, Tamulaitis G, Grazulis S, Bochtler M, Siksnys V.
Nucleic Acids Res.. 2018
Specificity of MLL1 and TET3 CXXC domains towards naturally occurring cytosine modifications.
Stroynowska-Czerwinska A, Piasecka A, Bochtler M.
Biochim Biophys Acta Gene Regul Mech.. 2018
Possible association of the TERT promoter polymorphisms rs2735940, rs7712562 and rs2853669 with diabetes mellitus in obese elderly Polish population: results from the national PolSenior study.
Gutmajster E, Chudek J, Augusciak-Duma A, Szwed M, Szybalska A, Mossakowska M, Puzianowska-Kuznicka M, Wiecek A, Sieron AL.
J Appl Genet. . 2018
Atrial fibrillation independently linked with depression in communitydwelling older population. Results from the nationwide PolSenior project.
Rewiuk K, Wizner B, Klich-Rączka A, Więcek A, Mossakowska M, Chudek J, Szybalska A, Broczek K, Zdrojewski T, Grodzicki T.
Exp Gerontol. . 2018
Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins.
Kowalski L, Bragoszewski P, Khmelinskii A, Glow E, Knop M, Chacinska A.
BMC Biol. . 2018
Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species.
Topf U, Suppanz I, Samluk L, Wrobel L, Böser A, Sakowska P, Knapp B, Pietrzyk MK, Chacinska A, Warscheid B.
Nat Commun. . 2018
The topology of lymphotoxin β receptor accumulated upon endolysosomal dysfunction dictates the NF-κB signaling outcome.
Banach-Orłowska M, Jastrzębski K, Cendrowski J, Maksymowicz M, Wojciechowska K, Korostyński M, Moreau D, Gruenberg J, Miaczynska M.
J Cell Sci.. 2018
Huntingtin-Associated Protein 1A Regulates Store-Operated Calcium Entry in Medium Spiny Neurons From Transgenic YAC128 Mice, a Model of Huntington’s Disease.
Czeredys M, Vigont VA, Boeva VA, Mikoshiba K, Kaznacheyeva EV, Kuznicki J.
Front Cell Neurosci.. 2018
Crystal structure of human Acinus RNA recognition motif domain.
Fernandes H, Czapinska H, Grudziaz K, Bujnicki JM, Nowacka M.
PeerJ.. 2018
Bioinformatics Tools and Benchmarks for Computational Docking and 3D Structure Prediction of RNA-Protein Complexes.
Nithin C, Ghosh P, Bujnicki JM.
Genes (Basel). 2018
Prevalence of anemia in relation to socio-economic factors in elderly Polish population: the results of PolSenior study.
Styszynski A, Mossakowska M, Chudek J, Puzianowska-Kuznicka M, Klich-Raczka A, Neumann-Podczaska A, Szybalska A, Wieczorowska-Tobis K.
J Physiol Pharmacol.. 2018
Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanism.
Walerych D, Pruszko M, Zyla L, Wezyk M, Gaweda-Walerych K, Zylicz A.
Oncotarget. 2018
Dental status in the Polish senior population and its correlates-Results of the national survey PolSenior.
Mehr K, Olszanecka-Glinianowicz M, Chudek J, Szybalska A, Mossakowska M, Zejda J, Wieczorowska-Tobis K, Grodzicki T, Piotrowski P.
Gerodontology. 2018
Crystal structure of the modification-dependent SRA-HNH endonuclease TagI
Kisiala M, Copelas A, Czapinska H, Xu S, Bochtler M.
Nucleic Acids Res.. 2018
Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Kumari P, Aeschimann F, Gaidatzis D, Keusch JJ, Ghosh P, Neagu A, Pachulska-Wieczorek K, Bujnicki JM, Gut H, Großhans H, Ciosk R.
Nat Commun.. 2018
Novel inhibitors of the rRNA ErmC' methyltransferase to block resistance to macrolides, lincosamides, streptogramine B antibiotics.
Foik IP, Tuszynska I, Feder M, Purta E, Stefaniak F, Bujnicki JM.
Eur J Med Chem.. 2018
Activity and structure of EcoKMcrA.
Czapinska H, Kowalska M, Zagorskaite E, Manakova E, Slyvka A, Xu SY, Siksnys V, Sasnauskas G, Bochtler M.
Nucleic Acids Res.. 2018
Antisense and yet sensitive: Copy number control of rolling circle-replicating plasmids by small RNAs.
Pluta R, Espinosa M.
Wiley Interdiscip Rev RNA. 2018
Self-rated health and its association with all-cause mortality of older adults in Poland: The PolSenior project.
Szybalska A, Broczek K, Puzianowska-Kuznicka M, Slusarczyk P, Chudek J, Skalska A, Mossakowska M.
Arch Gerontol Geriatr.. 2018
Neuronal calcium signaling via store-operated channels in health and disease.
Wegierski T, Kuznicki J.
Cell Calcium.. 2018
The translational regulation of maternal mRNAs in time and space.
Winata CL, Korzh V.
FEBS Lett. . 2018
The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients.
Koyuncu S, Saez I, Lee HJ, Gutierrez-Garcia R, Pokrzywa W, Fatima A, Hoppe T, Vilchez D.
Nat Commun.. 2018
Plasma concentration of Retinol Binding Protein 4 (RBP4) in relation to nutritional status and kidney function in older population of PolSenior Study.
Kocełak P, Owczarek A, Bożentowicz-Wikarek M, Brzozowska A, Mossakowska M, Grodzicki T, Więcek A, Chudek J, Olszanecka-Glinianowicz M.
Adv Med Sci.. 2018
Plasma Level of Retinol-Binding Protein 4, N-Terminal proBNP and Renal Function in Older Patients Hospitalized for Heart Failure.
Majerczyk M, Choręza P, Mizia-Stec K, Bożentowicz-Wikarek M, Brzozowska A, Arabzada H, Owczarek AJ, Szybalska A, Grodzicki T, Więcek A, Olszanecka-Glinianowicz M, Chudek J.
Cardiorenal Med.. 2018
Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages.
Donzelli S, Milano E, Pruszko M, Sacconi A, Masciarelli S, Iosue I, Melucci E, Gallo E, Terrenato I, Mottolese M, Zylicz M, Zylicz A, Fazi F, Blandino G, Fontemaggi G.
Breast Cancer Res.. 2018
Utilization of medical rehabilitation services among older Poles: results of the PolSenior study.
Szybalska A, Broczek K, Slusarczyk P, Kozdron, Chudek J, Puzianowska‑Kuznicka M, Kostka T, Skalska A, Mossakowska M.
Eur Geriatr Med.. 2018
Decoding the Heart through Next Generation Sequencing Approaches.
Pawlak M, Niescierowicz K, Winata CL.
Genes (Basel). . 2018
SIRT1, miR-132 and miR-212 link human longevity to Alzheimer's Disease.
Hadar A, Milanesi E, Walczak M, Puzianowska-Kuźnicka M, Kuźnicki J, Squassina A, Niola P, Chillotti C, Attems J, Gozes I, Gurwitz D.
Sci Rep.. 2018
CAVER Analyst 2.0: Analysis and Visualization of Channels and Tunnels in Protein Structures and Molecular Dynamics Trajectories.
Jurcik A, Bednar D, Byska J, Marques SM, Furmanova K, Daniel L, Kokkonen P, Brezovsky J, Strnad O, Stourac J, Pavelka A, Manak M, Damborsky J, Kozlikova B.
Bioinformatics. 2018
5′-Phosphorothiolate Dinucleotide Cap Analogues: Reagents for Messenger RNA Modification and Potent Small-Molecular Inhibitors of Decapping Enzymes.
Wojtczak BA, Sikorski PJ, Fac-Dabrowska K, Nowicka A, Warminski M, Kubacka D, Nowak E, Nowotny M, Kowalska J, Jemielity J.
J Am Chem Soc.. 2018
A Protocol for Laboratory Housing of Turquoise Killifish (Nothobranchius furzeri).
Dodzian J, Kean S, Seidel J, Valenzano DR.
Journal of Visualized Experiments (JoVE). 2018
Quality of life related to oral, subcutaneous, and intravenous biologic treatment of inflammatory bowel disease: a time trade-off study.
Holko P, Kawalec P, Mossakowska M.
J Gastroenterol Hepatol. 2018
Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants.
NCD Risk Factor Collaboration (Mossakowska M and Slusarczyk P)
Int J Epidemiol. . 2018
The utilization of health resort treatment services by older people in Poland – results of the PolSenior study.
Szybalska A, Broczek K, Ślusarczyk P, Kozdroń E, Błędowski P, Chudek J, Mossakowska M.
Gerontologia Polska. 2018
Ubiquitylation Pathways In Insulin Signaling and Organismal Homeostasis.
Balaji V, Pokrzywa W, Hoppe T.
Bioessays. 2018
Chaperoning the guardian of the genome. The two-faced role of molecular chaperones in p53 tumor suppressor action.
Wawrzynow B, Zylicz A, Zylicz M.
BBA-Rev Cancer. 2018
Components of metabolic syndrome in relation to plasma levels of retinol binding protein 4 (RBP4) in a cohort of people aged 65 years and older.
Majerczyk M, Kocełak P, Choręza P, Arabzada H, Owczarek AJ, Bożentowicz-Wikarek M, Brzozowska A, Szybalska A, Puzianowska-Kuźnicka M, Grodzicki T, Więcek A, Olszanecka-Glinianowicz M, Chudek J.
J Endocrinol Invest.. 2018
The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers.
Piasecka A, Czapinska H, Vielberg MT, Szczepanowski RH, Kiefersauer R, Reed S, Groll M, Bochtler M.
J Mol Biol.. 2018
MODOMICS: a database of RNA modification pathways. 2017 update.
Boccaletto P, Machnicka MA, Purta E, Piatkowski P, Baginski B, Wirecki TK, de Crécy-Lagard V, Ross R, Limbach PA, Kotter A, Helm M, Bujnicki JM.
Nucleic Acids Res.. 2018
Socio-economic determinants of vitamin D deficiency in the older Polish population: results from the PolSenior study.
Wyskida M, Owczarek A, Szybalska A, Brzozowska A, Szczerbowska I, Wieczorowska-Tobis K, Puzianowska-Kuźnicka M, Franek E, Mossakowska M, Grodzicki T, Więcek A, Olszanecka-Glinianowicz M, Chudek J.
Public Health Nutr.. 2018
Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components.
Razew M, Warkocki Z, Taube M, Kolondra A, Czarnocki-Cieciura M, Nowak E, Labedzka-Dmoch K, Kawinska A, Piatkowski J, Golik P, Kozak M, Dziembowski A, Nowotny M.
Nat Commun.. 2018
Health status of older cancer survivors—results of the PolSenior study.
Sulicka J, Pac A, Puzianowska-Kuźnicka M, Zdrojewski T, Chudek J, Tobiasz-Adamczyk B, Mossakowska M, Skalska A, Więcek A, Grodzicki T.
Journal of Cancer Survivorship. 2018
Cytoplasmic polyadenylation-mediated translational control of maternal mRNAs directs maternal to zygotic transition.
Winata CL, Łapiński M, Pryszcz L, Vaz C, Bin Ismail MH, Nama S, Hajan HS, Lee SGP, Korzh V, Sampath P, Tanavde V, Mathavan S.
Development.. 2018
Novel role for the testis-enriched HSPA2 protein in regulating epidermal keratinocyte differentiation.
Gogler-Pigłowska A, Klarzyńska K, Sojka DR, Habryka A, Głowala-Kosińska M, Herok M, Kryj M, Halczok M, Krawczyk Z, Scieglinska D.
J Cell Physiol.. 2018
GSK3β Controls mTOR and Prosurvival Signaling in Neurons.
Urbanska M, Gozdz A, Macias M, Cymerman IA, Liszewska E, Kondratiuk I, Devijver H, Lechat B, Van Leuven F, Jaworski J.
Mol Neurobiol.. 2018
RNArchitecture: a database and a classification system of RNA families, with a focus on structural information.
Boccaletto P, Magnus M, Almeida C, Zyla A, Astha A, Pluta R, Baginski B, Jankowska E, Dunin-Horkawicz S, Wirecki TK, Boniecki MJ, Stefaniak F, Bujnicki JM.
Nucleic Acids Res.. 2018
Blocking c-Fos Expression Reveals the Role of Auditory Cortex Plasticity in Sound Frequency Discrimination Learning
de Hoz L, Gierej D, Lioudyno V, Jaworski J, Blazejczyk M, Cruces-Solís H, Beroun A, Lebitko T, Nikolaev T, Knapska E, Nelken I, Kaczmarek L
Cereb Cortex. 2018
Adaptor Complex 2 Controls Dendrite Morphology via mTOR-Dependent Expression of GluA2
Koscielny A, Malik AR, Liszewska E, Zmorzynska J, Tempes A, Tarkowski B, Jaworski J
Mol Neurobiol. 2018
2017
Tight junction protein ZO-1 controls organic cation/carnitine transporter OCTN2 (SLC22A5) in a protein kinase C-dependent way.
Jurkiewicz D, Michalec K, Skowronek K, Nałęcz KA.
Biochim Biophys Acta Mol Cell Res.. 2017
Development of Circumventricular Organs in the Mirror of Zebrafish Enhancer-Trap Transgenics.
García-Lecea M, Gasanov E, Jedrychowska J, Kondrychyn I, Teh C, You MS, Korzh V.
Front Neuroanat. . 2017
ZnO@Gd2O3 core/shell nanoparticles for biomedical applications: Physicochemical, in vitro and in vivo characterization.
Woźniak A, Grześkowiak BF, Babayevska N, Zalewski T, Drobna M, Woźniak-Budych M, Wiweger M, Słomski R, Jurga S.
Mater Sci Eng C Mater Biol Appl. . 2017
Nei-like 1 (NEIL1) excises 5-carboxylcytosine directly and stimulates TDG-mediated 5-formyl and 5-carboxylcytosine excision.
Slyvka A, Mierzejewska K, Bochtler M.
Sci Rep.. 2017
Mikroskopowe obrazowanie jonów wapnia za pomocą genetycznie kodowanych sond (Microscopic imaging of calcium ions with genetically encoded calcium indicators).
Gazda K, Bazała M, Węgierski T.
Postepy Biochem.. 2017
Impact of the structural integrity of the three-way junction of adenovirus VAI RNA on PKR inhibition.
Dzananovic E, Astha, Chojnowski G, Deo S, Booy EP, Padilla-Meier P, McEleney K, Bujnicki JM, Patel TR, McKenna SA.
PLoS One. 2017
Occurrence and stability of lone pair-π stacking interactions between ribose and nucleobases in functional RNAs.
Chawla M, Chermak E, Zhang Q, Bujnicki JM, Oliva R, Cavallo L.
Nucleic Acids Res.. 2017
SupeRNAlign: a new tool for flexible superposition of homologous RNA structures and inference of accurate structure-based sequence alignments.
Piątkowski P, Jabłońska J, Żyła A, Niedziałek, Matelska D, Jankowska E, Waleń T, Dawson WK, Bujnicki JM.
Nucleic Acids Res.. 2017
PET/CT evaluation of 18F-FDG uptake in pericoronary adipose tissue in patients with stable coronary artery disease: Independent predictor of atherosclerotic lesions' formation?
Mazurek T, Kobylecka M, Zielenkiewicz M, Kurek A, Kochman J, Filipiak KJ, Mazurek K, Huczek Z, Królicki L, Opolski G.
J Nucl Cardiol. 2017
Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study.
Brendel M, Focke C, Blume T, Peters F, Deussing M, Probst F, Jaworska A, Overhoff F, Albert N, Lindner S, von Ungern-Sternberg B, Bartenstein P, Haass C, Kleinberger G, Herms J, Rominger A.
J Nucl Med.. 2017
Overexpression of STIM1 in neurons in mouse brain improves contextual learning and impairs long-term depression.
Majewski Ł, Maciąg F, Boguszewski PM, Wasilewska I, Wiera G, Wójtowicz T, Mozrzymas J, Kuznicki J.
Biochim Biophys Acta. 2017
Visualization of cytosolic ribosomes on the surface of mitochondria by electron cryo-tomography.
Gold VA, Chroscicki P, Bragoszewski P, Chacinska A.
EMBO Rep.. 2017
Endosomal "sort" of signaling control: The role of ESCRT machinery in regulation of receptor-mediated signaling pathways.
Szymanska E, Budick-Harmelin N, Miaczynska M.
Semin Cell Dev Biol.. 2017
Knockdown of amyloid precursor protein increases calcium levels in the endoplasmic reticulum.
Gazda K, Kuznicki J, Wegierski T.
Sci Rep. 2017
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults.
NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M & Slusarczyk P.
Lancet. 2017
Hepcidin is regulated by promoter-associated histone acetylation and HDAC3
Pasricha SR, Lim PJ, Duarte TL, Casu C, Oosterhuis D, Mleczko-Sanecka K, Suciu M, Da Silva AR, Al-Hourani K, Arezes J, McHugh K, Gooding S, Frost JN, Wray K, Santos A, Porto G, Repapi E, Gray N, Draper SJ, Ashley N, Soilleux E, Olinga P, Muckenthaler MU, Hughes JR, Rivella S, Milne TA, Armitage AE, Drakesmith H.
Nat Commun. 2017
The canonical way to make a heart: β-catenin and plakoglobin in heart development and remodeling
Piven OO, Winata CL
Experimental Biology and Medicine. 2017
The siRNA suppressor RTL1 is redox-regulated through glutathionylation of a conserved cysteine in the double-stranded-RNA-binding domain.
Charbonnel C, Niazi AK, Elvira-Matelot E, Nowak E, Zytnicki M, de Bures A, Jobet E, Opsomer A, Shamandi N, Nowotny M, Carapito C, Reichheld J-P, Vaucheret H, Saez-Vasquez J.
Nucleic Acids Res.. 2017
mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.
Rydzik AM, Warminski M, Sikorski PJ, Baranowski MR, Walczak S, Kowalska J, Zuberek J, Lukaszewicz M, Nowak E, W Claridge TD, Darzynkiewicz E, Nowotny M, Jemielity J.
Nucleic Acids Res. 2017
P53 Dysfunction in Neurodegenerative Diseases – The Cause or Effect of Pathological Changes?
Szybinska A, Lesniak W
Aging Dis.. 2017
Antiplatelet and anticoagulant therapy in elderly people with type 2 diabetes mellitus in Poland (based on the PolSenior Study)
Łabuz-Roszak B, Machowska-Majchrzak A, Skrzypek M, Mossakowska M, Chudek J, Więcek A, Wawrzyńczyk M, Łącka-Gaździk B, Pierzchała K
Arch Med Sci. 2017
Ikk2 regulates cytokinesis during vertebrate development
Shen H, Shin EM, Lee S, Mathavan S, Koh H, Osato M, Choi H, Tergaonkar V, Korzh V
Sci Rep. 2017
Chapter Six - Structural Studies of RNases H2 as an Example of Crystal Structure Determination of Protein–Nucleic Acid Complexes
Figiel M, Nowotny M
Methods in Enzymology. 2017
Coordination between the polymerase and RNase H activity of HIV-1 reverse transcriptase
Figiel M, Krepl M, Poznanski J, Golab A, Šponer J, Nowotny M
Nucleic Acids Res.. 2017
Chaperone-directed ubiquitylation maintains proteostasis at the expense of longevity.
Pokrzywa W, Lorenz R, Hoppe T
Worm. 2017
Pharmacological stroke prevention in the elderly with atrial fibrillation in Poland - Results of PolSenior study
Łabuz-Roszak B, Skrzypek M, Machowska-Majchrzak A, Mossakowska M, Chudek J, Więcek A, Pierzchała K, Łącka-Gaździk B, Grodzicki T
Neurol Neurochir Pol. 2017
TRIM28 epigenetic corepressor is indispensable for stable induced pluripotent stem cell formation
Klimczak M, Czerwińska P, Mazurek S, Sozańska B, Biecek P, Mackiewicz A, Wiznerowicz M
Stem Cell Research. 2017
Imatinib and spironolactone suppress hepcidin expression
Mleczko-Sanecka K, da Silva AR, Call D, Neves J, Schmeer N, Damm G, Seehofer D, Muckenthaler MU
Haematologica. 2017
GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation
Gozdz A, Nikolaienko O, Urbanska M, Cymerman IA, Sitkiewicz E, Blazejczyk M, Dadlez M, Bramham CR, Jaworski J
Front Mol Neurosci. 2017
Repair or Destruction: An Intimate Liaison Between Ubiquitin Ligases and Molecular Chaperones in Proteostasis
Kevei É, Pokrzywa W, Hoppe T
FEBS Lett. doi:10.1002/1873-3468.12750.. 2017
Identification of a Na+/K+-ATPase inhibition-independent proarrhythmic ionic mechanisms of cardiac glycosides
Koh CH, Wu J, Chung YY, Liu Z, Zhang RR, Chong K, Korzh V, Ting S, Oh S, Shim W, Tian HY, Wei H
Sci Rep.. 2017
Responsive mesoporous silica nanoparticles for sensing of hydrogen peroxide and simultaneous treatment toward heart failure
Tan SY, Teh C, Ang CY, Li M, Li P, Korzh V, Zhao Y
Nanoscale. 2017
miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans
Owczarz M, Budzinska M, Domaszewska-Szostek A, Borkowska J, Polosak J, Gewartowska M, Slusarczyk P, Puzianowska-Kuznicka M
Experimental Biology and Medicine. 2017
Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation
Tracz-Gaszewska Z, Klimczak M, Biecek P, Herok M, Kosinski M, Olszewski MB, Czerwińska P, Wiech M, Wiznerowicz M, Zylicz A, Zylicz M, Wawrzynow B
Oncotarget. 2017
The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1
Pruszko M, Milano E, Forcato M, Donzelli S, Ganci F, Di Agostino S, De Panfilis S, Fazi F, Bates DO, Bicciato S, Zylicz M, Zylicz A, Blandino G, Fontemaggi G
EMBO Rep. 2017
Mutations in human AID differentially affect its ability to deaminate cytidine and 5-methylcytidine in ssDNA substrates in vitro
Budzko L, Jackowiak P, Kamel K, Sarzynska J, Bujnicki JM, Figlerowicz M
Sci Rep. 2017
Defining the crucial domain and amino acid residues in bacterial Lon protease for DNA binding and processing of DNA-interacting substrates
Karlowicz A, Wegrzyn K, Gross M, Kaczynska D, Ropelewska M, Siemiątkowska M, Bujnicki JM, Konieczny I
J Biol Chem. 2017
RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme
Miao Z, Adamiak RW, Antczak M, Batey RT, Becka A, Biesiada M, Boniecki MJ, Bujnicki JM, Chen S, Cheng CY, Chou F, Ferré-D'Amaré AR, Das R, Dawson WK, Ding F, Dokholyan NV, Dunin-Horkawicz S, Geniesse C, Kappel K, Kladwang W, Krokhotin A, Lach GE, Major F, Mann TH, Magnus M, Pachulska-Wieczorek K, Patel DJ, Piccirilli JA, Popenda M, Purzycka KJ, Ren A, Rice GM, Santalucia J Jr, Sarzynska J, Szachniuk M, Tandon A, Trausch JJ, Tian S, Wang J, Weeks KM, Williams B II, Xiao Y, Xu X, Zhang D, Zok T, Westhof E
RNA. 2017
ZBP1 phosphorylation at serine 181 regulates its dendritic transport and the development of dendritic trees of hippocampal neurons
Urbanska AS, Janusz-Kaminska A, Switon K, Hawthorne AL, Perycz M, Urbanska M, Bassell GJ, Jaworski J
Sci Rep. 2017
Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration
Kononenko NL, Claßen GA, Kuijpers M, Puchkov D, Maritzen T, Tempes A, Malik AR, Skalecka A, Bera S, Jaworski J, Haucke V
Nat Commun. 2017
Control of mitochondrial biogenesis and function by the ubiquitin-proteasome system
Bragoszewski P, Turek M, Chacinska A.
Open Biol. 2017
Personalized genome sequencing coupled with iPSC technology identifies GTDC1 as a gene involved in neurodevelopmental disorders
Aksoy I, Utami KH, Winata CL, Hillmer AM, Rouam SL, Briault S, Davila S, Stanton LW, Cacheux V
Hum Mol Genet. 2017
Disease activity, quality of life, and indirect costs of ulcerative colitis in Poland
Kawalec P, Stawowczyk E, Mossakowska M, Pilc A
Prz Gastroenterol. 2017
Profile of 6 microRNA in blood plasma distinguish early stage Alzheimer's disease patients from non-demented subjects
Nagaraj S, Laskowska-Kaszub K, Dębski KJ, Wojsiat J, Dąbrowski M, Gabryelewicz T, Kuźnicki J, Wojda U
Oncotarget. 2017
Increase of TREM2 during Aging of an Alzheimer’s Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis
Brendel M, Kleinberger G, Probst F, Jaworska A, Overhoff F, Blume T, Albert NL, Carlsen J, Lindner S, Gildehaus FJ, Ozmen L, Suárez-Calvet M, Bartenstein P, Baumann K, Ewers M, Herms J, Haass C, Rominger A
Front. Aging Neurosci.. 2017
Increased plasma RBP4 concentration in older hypertensives is related to the decreased kidney function and the number of antihypertensive drugs-results from the PolSenior substudy
Majerczyk M, Choręza P, Bożentowicz-Wikarek M, Brzozowska A, Arabzada H, Owczarek A, Mossakowska M, Grodzicki T, Zdrojewski T, Więcek A, Olszanecka-Glinianowicz M, Chudek J
J Am Soc Hypertens. 2017
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
NCD Risk Factor Collaboration (Mossakowska M and Slusarczyk P)
Lancet. 2017
Multiple routes of endocytic internalization of PDGFRβ contribute to PDGF-induced STAT3 signaling
Jastrzębski K, Zdżalik-Bielecka D, Mamińska A, Kalaidzidis Y, Hellberg C, Miaczynska M
J Cell Sci.. 2017
Molecular neurobiology of mTOR
Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J
Neuroscience. 2017
A TALE-inspired computational screen for proteins that contain approximate tandem repeats.
Perycz M, Krwawicz J, Bochtler M.
PLoS One. 2017
Structural studies of RNA-protein complexes: A hybrid approach involving hydrodynamics, scattering and computational methods
Patel T, Chojnowski G, Astha, Koul A, McKenna S, Bujnicki JM
Methods. 2017
Inhibition of the mitochondrial calcium uniporter (MCU) rescues dopaminergic neurons in pink1-/- zebrafish
Soman S, Keatinge M, Moein M, DaCosta M, Mortiboys H, Skupin A, Sugunan S, Bazala M, Kuznicki J, Bandmann O
Eur J Neurosci.. 2017
TCF7L2 mediates the cellular and behavioral response to chronic lithium treatment in animal models
Misztal K, Brozko N, Nagalski A, Szewczyk LM, Królak M, Brzozowska K, Kuznicki J, Wisniewska MB
Neuropharmacology. 2017
PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD.
Gross B, Pawlak M, Lefebvre P, Staels B.
Nat Rev Endocrinol TEST. 2017
Tetrahydrocarbazoles decrease elevated SOCE in medium spiny neurons from transgenic YAC128 mice, a model of Huntington's disease
Czeredys M, Maciag F, Methner A, Kuznicki J
Biochem Biophys Res Commun. 2017
ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons
Szewczyk LM, Brozko N, Nagalski A, Rӧckle I, Werneburg S, Hildebrandt H, Wisniewska MB, Kuznicki J free access
Glia. 2017
Kainic Acid Induces mTORC1-Dependent Expression of Elmo1 in Hippocampal Neurons
Blazejczyk M, Macias M, Korostynski M, Firkowska M, Piechota M, Skalecka A, Tempes A, Koscielny A, Urbanska M, Przewlocki R, Jaworski J
Mol Neurobiol. 2017
GSK-3β and MMP-9 Cooperate in the Control of Dendritic Spine Morphology
Kondratiuk I, Łęski S, Urbańska M, Biecek P, Devijver H, Lechat B, Van Leuven F, Kaczmarek L, Jaworski T
Mol Neurobiol. 2017
2016
In-silico driven engineering of enantioselectivity of a penicillin G acylase towards active pharmaceutical ingredients.
Grulich M, Brezovský J, Štěpánek V, Palyzová A, Marešová H, Zahradník J, Kyslíková E, Kyslík P.
J Mol Catal B Enzym. 2016
Sequence-specific endoribonucleases.
Głów D, Nowacka M, Skowronek KJ, Bujnicki JM.
Postępy Biochemii. 2016
Okiem ryby - nowe spojrzenie na rozwój sieci neuronalnych i choroby neurorozwojowe.
Kędra M, Jaworski J, Zmorzyńska J.
Wszechświat . 2016
Białka z rodziny ID w inicjacji i progresji nowotworów (Białka z rodziny ID w inicjacji i progresji nowotworów).
Pruszko M, Żylicz A.
Postępy Biochemii. 2016
Be Healthy as a Fish Educational Program at the International Institute of Molecular and Cell Biology in Warsaw, Poland.
Goś D, Szymańska E, Białek-Wyrzykowska U, Wiweger M, Kuźnicki J.
Zebrafish. 2016
Health-Related Quality of Life Impairment and Indirect Cost of Crohn's Disease: A Self-Report Study in Poland
Holko P, Kawalec P, Mossakowska M, Pilc A
PLoS One. 2016
Coarse-grained modeling of RNA 3D structure
Dawson WK, Maciejczyk M, Jankowska EJ, Bujnicki JM
Methods. 2016
tRNAmodpred: A computational method for predicting posttranscriptional modifications in tRNAs
Machnicka MA, Dunin-Horkawicz S, de Crécy-Lagard V, Bujnicki JM
Methods. 2016
Asymmetric DNA methylation by dimeric EcoP15I DNA methyltransferase
Urulangodi M, Dhanaraju R, Gupta K, Roy RP, Bujnicki JM, Rao DN
Biochimie. 2016
MQAPsingle: A quasi single-model approach for estimation of the quality of individual protein structure models
Pawlowski M, Kozlowski L, Kloczkowski A
Proteins. 2016
Molecularly Imprinted Polymer (MIP) Film with Improved Surface Area Developed by Using Metal-Organic Framework (MOF) for Sensitive Lipocalin (NGAL) Determination.
Iskierko Z, Sharma PS, Prochowicz D, Fronc K, D'Souza F, Toczydłowska D, Stefaniak F, Noworyta K
ACS Appl Mater Interfaces.. 2016
Identification of protein structural elements responsible for the diversity of sequence preferences among Mini-III RNases.
Glow D, Kurkowska M, Czarnecka J, Szczepaniak K, Pianka D, Kappert V, Bujnicki JM, Skowronek KJ
Sci Rep.. 2016
A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans
Kalisiak K, Kuliński TM, Tomecki R, Cysewski D, Pietras Z, Chlebowski A, Kowalska K, Dziembowski A
Nucleic Acids Res. 2016
Health status correlates of malnutrition in the polish elderly population - Results of the Polsenior Study
Krzyminska-Siemaszko R, Chudek J, Suwalska A, Lewandowicz M, Mossakowska M, Kroll-Balcerzak R, Wizner B, Tobis S, Mehr K, Wieczorowska-Tobis K
Eur Rev Med Pharmacol Sci. 2016
miR-96, miR-145 and miR-9 expression increases, and IGF-1R and FOXO1 expression decreases in peripheral blood mononuclear cells of aging humans
Budzinska M, Owczarz M, Pawlik-Pachucka E, Roszkowska-Gancarz M , Slusarczyk P, Puzianowska-Kuznicka M
BMC Geriatr. 2016
A century of trends in adult human height
NCD Risk Factor Collaboration (793 Collaborators within M. Mossakowska and P. Ślusarczyk)
Elife. 2016
Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes
Tudek B, Zdżalik-Bielecka D, Tudek A, Kosicki K, Fabisiewicz A, Speina E
Free Radic Biol Med. 2016
DNA demethylation pathways: Additional players and regulators
Bochtler M, Kolano A, Xu G-L
Bioessays. 2016
miR-132 Regulates Dendritic Spine Structure by Direct Targeting of Matrix Metalloproteinase 9 mRNA
Jasińska M, Miłek J, Cymerman IA, Łęski S, Kaczmarek L, Dziembowska M
Mol Neurobiol.. 2016
Type III CRISPR complexes from Thermus thermophilus
Szychowska M, Siwek W, Pawolski D, Kazrani AA, Pyrc K, Bochtler M
Acta Biochim Pol. 2016
Protein trafficking at the crossroads to mitochondria
Wasilewski M, Chojnacka K, Chacinska A
Biochim Biophys Acta. 2016
Białka mitochondrialne – import, eksport, degradacja
Wasilewski M, Chojnacka K, Chacinska A
Postępy Biochemii. 2016
Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
Stracy M, Jaciuk M, Uphoff S, Kapanidis AN, Nowotny M, Sherratt DJ, Zawadzki P
Nat Commun.. 2016
Clustering of geriatric deficits emerges to be an essential feature of ageing - results of a cross-sectional study in Poland
Piotrowicz K, Pac A, Skalska AB, Chudek J, Klich-Rączka A, Szybalska A, Michel JP, Grodzicki T
Aging (Albany NY). 2016
Pseudoloma neurophilia (Microsporidia) – poważne zagrożenie dla hodowli laboratoryjnej danio pręgowanego (Danio rerio, Hamilton 1822)
Korzeniowski P, Wiweger M.
Życie Weterynaryjne. 2016
Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches
Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J
IUBMB Life. 2016
AMPA Receptors Are Involved in Store-Operated Calcium Entry and Interact with STIM Proteins in Rat Primary Cortical Neurons
Gruszczynska-Biegala J, Sladowska M, Kuznicki J
Frontiers in Cellular Neuroscience. 2016
Associations between cardiovascular disease risk factors and IL-6 and hsCRP levels in the elderly
Nadrowski P, Chudek J, Skrzypek M, Puzianowska-Kuźnicka M, Mossakowska M, Więcek A, Zdrojewski T, Grodzicki T, Kozakiewicz K
Exp Gerontol. 2016
TIM29 is a subunit of the human carrier translocase required for protein transport
Callegari S, Richter F, Chojnacka K, Jans DC, Lorenzi I, Pacheu-Grau D, Jakobs S, Lenz C, Urlaub H, Dudek J, Chacinska A, Rehling P
FEBS Lett. 2016
Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.
Mikula M, Skrzypczak M, Goryca K, Paczkowska K, Ledwon JK, Statkiewicz M, Kulecka M, Grzelak M, Dabrowska M, Kuklinska U, Karczmarski J, Rumienczyk I, Jastrzebski K, Miaczynska M, Ginalski K, Bomsztyk K, Ostrowski J.
Nucleic Acids Res. 2016
Microscopic analysis of Orai-mediated store-operated calcium entry in cells with experimentally altered levels of amyloid precursor protein
Wegierski T, Gazda K, Kuznicki J
Biochem Biophys Res Commun. 2016
Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue
Van Laer B, Roovers M, Wauters L, Kasprzak JM, Dyzma M, Deyaert E, Singh R, Feller A, Bujnicki JM, Droogmans L, Versées W
Nucleic Acids Res. 2016
Computational modeling of RNA 3D structures and interactions
Dawson WK, Bujnicki JM
Curr Opin Struct Biol. 2016
SimRNA: a coarse-grained method for RNA folding simulations and 3D structure prediction
Boniecki MJ, Lach G, Dawson WK, Tomala K, Lukasz P, Soltysinski T, Rother KM, Bujnicki JM
Nucleic Acids Res. 2016
The architecture of the Schizosaccharomyces pombe CCR4-NOT complex
Ukleja M, Cuellar J, Siwaszek A, Kasprzak JM, Czarnocki-Cieciura M, Bujnicki JM, Dziembowski A, Valpuesta J
Nature Commun. 2016
Loss of conserved non-coding RNAs in genomes of bacterial endosymbionts
Matelska D, Kurkowska M, Purta E, Bujnicki JM, Dunin-Horkawicz S
Genome Biol Evol. 2016
Genome-wide survey of codons under diversifying selection in a highly recombining bacterial species, Helicobacter pylori
Yahara K, Furuta Y, Morimoto S, Kikutake C, Komukai S, Matelska D, Dunin-Horkawicz S, Bujnicki JM, Uchiyama I, Kobayashi I
DNA Res. 2016
SimRNAweb: a web server for RNA 3D structure modeling with optional restraints
Magnus MM, Boniecki MJ, Dawson WK, Bujnicki JM
Nucleic Acids Res.. 2016
Haloferax volcanii UbaA, catalytic engine for sampylation and sulfur transfer
Bochtler M., Piasecka A
FEBS J. 2016
mTOR kinase is needed for the development and stabilization of dendritic arbors in newly born olfactory bulb neurons
Skałecka A, Liszewska E, Bilinski R, Gkogkas C, Khoutorsky A, Malik AR, Sonenberg N, Jaworski J
Dev Neurobiol. 2016
Endocytic regulation of cytokine receptor signaling
Cendrowski J, Mamińska A, Miaczynska M
Cytokine Growth Factor Rev. 2016
Expression of microRNAs miR21, miR146a, and miR155 in tuberous sclerosis complex cortical tubers and their regulation in human astrocytes and SEGA-derived cell cultures
van Scheppingen J, Iyer AM, Prabowo AS, Mühlebner A, Anink JJ, Scholl T, Feucht M, Jansen FE, Spliet WG, Krsek P, Zamecnik J, Buccoliero AM, Giordano F, Genitori L, Kotulska K, Jozwiak S, Jaworski J, Liszewska E, van Vliet EA, Aronica E
Glia. 2016
LytM Fusion with SH3b-Like Domain Expands Its Activity to Physiological Conditions
Jagielska E, Chojnacka O, Sabala I
Microb Drug Resist. 2016
Protein Import by the Mitochondrial Presequence Translocase in the Absence of a Membrane Potential
Turakhiya U, von der Malsburg K, Gold VA, Guiard B, Chacinska A, van der Laan M, Ieva R
J Mol Biol. 2016
Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants
Di Cesare M, … Mossakowska M, … Slusarczyk P, … - 756 collaborators (NCD-RisC)
Lancet. 2016
Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants
Zhou B, … Mossakowska M, … Slusarczyk P, … - 513 collaborators (NCD-RisC)
Lancet. 2016
Socioeconomic determinants of prostate-specific antigen testing and estimation of the prevalence of undiagnosed prostate cancer in an elderly Polish population based on the PolSenior study
Prajsner A, Chudek J, Szybalska A, Piotrowicz K, Zejda J, Więcek A
Arch Med Sci. 2016
Prevalence of chronic pain in the elderly Polish population – results of the PolSenior study
Kozak-Szkopek E, Broczek K, Slusarczyk P, Wieczorowska-Tobis K, Klich-Raczka A, Szybalska A, Mossakowska M
Arch Med Sci. 2016
The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly
Wrobel L, Sokol AM, Chojnacka M, Chacinska A
Sci Rep. 2016
Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study
Puzianowska-Kuznicka M, Owczarz M, Wieczorowska-Tobis K, Nadrowski P, Chudek J, Slusarczyk P, Skalska A, Jonas M, Franek E, Mossakowska M
Immunity & Ageing. 2016
On the role of steric clashes in methylation control of restriction endonuclease activity
Mierzejewska K, Bochtler M, Czapinska H
Nucleic Acids Res. 2016
Isolation of Plant Photosystem II Complexes by Fractional Solubilization
Haniewicz P, Floris D, Farci D, Kirkpatrick J, Loi MC, Büchel C, Bochtler M, Piano D
Front Plant Sci. 2016
Chatty Mitochondria: Keeping Balance in Cellular Protein Homeostasis
Topf U, Wrobel L, Chacinska A
Trends Cell Biol. 2016
TLR-6 SNP P249S is associated with healthy aging in nonsmoking Eastern European Caucasians - A cohort study
Hamann L, Bustami J, Iakoubov L, Szwed M, Mossakowska M, Schumann RR, Puzianowska-Kuznicka M
Immun Ageing. 2016
Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity
Kevenaar JT, Bianchi S, van Spronsen M, Olieric N, Lipka J,Frias CP, Mikhaylova M, Harterink M, Keijzer N, Wulf PS, Hilbert M, Kapitein LC, de Graaff E, Ahkmanova A, Steinmetz MO, Hoogenraad CC
Curr Biol. 2016
APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain
Song J, Mu Y, Li C, Bergh A, Miaczynska M, Heldin CH, Landström M
Oncotarget. 2016
ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors
Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M
Sci Signal. 2016
DANIO-CODE: Toward an Encyclopedia of DNA Elements in Zebrafish
Tan H, Onichtchouk D, Winata C
Zebrafish. 2016
Structure and mechanism of nucleases regulated by SLX4
Nowotny M, Gaur V
Curr Opin Struct Biol. 2016
Physical activity, body composition and general health status of physically active students of the University of the Third Age (U3A)
Zajac-Gawlak I, Pospiech D, Kroemeke A, Mossakowska M, Gába A, Pelclová J, Pridalová M, Kłapcinska B
Archives of Gerontology and Geriatrics. 2016
Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites
Lipka J, Kapitein LC, Jaworski J, Hoogenraad CC
EMBO J. 2016
Dextran Nanoparticle Synthesis and Properties
Wasiak I, Kulikowska A, Janczewska M, Michalak M, Cymerman IA, Nagalski A, Kallinger P, Szymanski WW, Ciach T
PLoS One. 2016
Prevalence, awareness, and control of hypertension in elderly and very elderly in Poland: results of a cross-sectional representative survey
Zdrojewski T, Wizner B, Więcek A, Ślusarczyk P, Chudek J, Mossakowska M, Bandosz P, Bobak M, Kozakiewicz K, Broda G, Wyrzykowski B, Grodzicki T
J Hypertens. 2016
Impaired dynamin 2 function leads to increased AP-1 transcriptional activity through the JNK/c-Jun pathway
Szymanska E, Skowronek A, Miaczynska M
Cell Signal. 2016
Molecular anatomy of the thalamic complex and the underlying transcription factors
Nagalski A, Puelles L, Dabrowski M, Wegierski T, Kuznicki J, Wisniewska MB
Brain Struct Funct. 2016
2015
Phylogenomics and sequence-structure-function relationships in the GmrSD family of Type IV restriction enzymes.
Machnicka AM, Kaminska KH, Dunin-Horkawicz S, Bujnicki JM.
BMC Bioinformatics. 2015
Molecular mechanisms of induced pluripotency.
Kulcenty K, Wróblewska J, Mazurek S, Liszewska E, Jaworski J.
Contemp Oncol (Pozn). 2015
NeuroMorph: A Toolset for the Morphometric Analysis and Visualization of 3D Models Derived from Electron Microscopy Image Stacks.
Jorstad A, Nigro B, Cali C, Wawrzyniak M, Fua P, Knott G.
Neuroinformatics. 2015
Research reforms: Ukrainian science needs elixir of youth.
Vassetzky Y, Gout I, Kuznicki J.
Nature. 2015
RNAcentral: a comprehensive database of non-coding RNA sequences
The RNAcentral Consortium (Petrov AI et al within Bujnicki JM)
Nucleic Acids Res. 2015
Functional and evolutionary analyses of Helicobacter pylori HP0231 (DsbK) protein with strong oxidative and chaperone activity characterized by a highly diverged dimerization domain
Bocian-Ostrzycka KM, Łasica AM, Dunin-Horkawicz S, Grzeszczuk MJ, Drabik K, Dobosz AM, Godlewska R, Nowak E, Collet J-F, Jagusztyn-Krynicka EK
Frontiers in Microbiology. 2015
APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments
Kalaidzidis I, Miaczynska M, Brewińska-Olchowik M, Hupalowska A, Ferguson C, Parton RG, Kalaidzidis Y, Zerial M
J Cell Biol. 2015
Magnesium binding architectures in RNA crystal structures: validation binding preferences, classification, and motif detection
Zheng H, Shabalin I, Handing K, Bujnicki JM, Minor M
Nucleic Acids Res. 2015
NPDock – a web server for protein-nucleic acid docking
Tuszynska I, Magnus M, Jonak K, Dawson W, Bujnicki JM
Nucleic Acids Res. 2015
Biochemical Characterization and Validation of a Catalytic Site of a Highly Thermostable Ts2631 Endolysin from the Thermus scotoductus Phage vB_Tsc2631
Plotka M, Kaczorowska AK, Morzywolek A, Makowska J, Kozlowski LP, Thorisdottir A, Skírnisdottir S, Hjörleifsdottir S, Fridjonsson OH, Hreggvidsson GO, Kristjansson JK, Dabrowski S, Bujnicki JM, Kaczorowski T
PLoS One. 2015
Computational methods for prediction of RNA interactions with metal ions and small organic ligands
Philips A, Lach G, Bujnicki JM
Methods Enzymol. 2015
RNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures
Miao Z, Adamiak RW, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cheng C, Chojnowski G, Chou FC, Cordero P, Cruz JA, Ferré-D'amaré AR, Das R, Ding F, Dokholyan NV, Dunin-Horkawicz S, Kladwang W, Krokhotin A, Lach G, Magnus M, Major F, Mann TH, Masquida B, Matelska D, Meyer M, Peselis A, Popenda M, Purzycka KJ, Serganov A, Stasiewicz J, Szachniuk M, Tandon A, Tian S, Wang J, Xiao Y, Xu X, Zhang J, Zhao P, Zok T, Westhof E
RNA. 2015
A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing
Liu S, Mozaffari-Jovin S, Wollenhaupt J, Santos KF, Theuser M, Dunin-Horkawicz S, Fabrizio P, Bujnicki JM, Lührmann R, Wahl MC
eLife. 2015
Sequence-specific cleavage of dsRNA by Mini-III RNase
Glow D, Pianka D, Sulej A, Kozlowski L, Czarnecka J, Chojnowski G, Skowronek KJ, Bujnicki JM
Nucleic Acids Res. 2015
Characterization of the termini of the West Nile virus genome and their interactions with the small isoform of the 2' 5'-Oligoadenylate Synthetase family
Deo S, Patel TR, Chojnowski G, Koul A, Dzananovic E, McEleney K, Bujnicki JM, McKenna SA
J Struct Biol. 2015
Structure and intrinsic disorder of the proteins of the Trypanosoma brucei editosome
Czerwoniec A, Kasprzak JM, Bytner P, Dobrychlop M, Bujnicki JM
FEBS Lett. 2015
Brickworx builds recurrent RNA and DNA structural motifs into medium and low-resolution electron density maps
Chojnowski G, Walen T, Piatkowski P, Potrzebowski W, Bujnicki JM
Acta Crystallogr D Biol Crystallogr. 2015
An atlas of RNA base pairs involving modified nucleobases with optimal geometries and accurate energies
Chawla M, Oliva R, Bujnicki JM, Cavallo L
Nucleic Acids Res. 2015
A magnetic origin of cuprate superconductivity? A MaxEnt-mu SR view
Boekema C, Owens F, Love A, Li Z, Sakkaris P, Dawson WK
Int J Mod Phys B. 2015
The signature of the five-stranded vRRM fold defined by functional, structural and computational analysis of the hnRNP L protein
Blatter M, Dunin-Horkawicz S, Grishina I, Maris C, Thore S, Maier T, Bindereif A, Bujnicki JM, Allain FHT
J Mol Biol. 2015
Functional and evolutionary analyses of Helicobacter pylori HP0231 (DsbK) protein with strong oxidative and chaperone activity characterized by a highly diverged dimerization domain
Bocian-Ostrzycka KM, Łasica AM, Dunin-Horkawicz S, Grzeszczuk MJ, Drabik K, Dobosz AM, Godlewska R, Nowak E, Collet J-F, Jagusztyn-Krynicka EK
Frontiers in Microbiology. 2015
High resolution structure of an M23 peptidase with a substrate analogue
Grabowska M, Jagielska E, Czapinska H, Bochtler M, Sabala I
Sci Rep. 2015
Functional Analysis of Porphyromonas gingivalis W83 CRISPR-Cas Systems
Burmistrz M, Dudek B, Staniec D, Rodriguez Martinez JI, Bochtler M, Potempa J, Pyrc K
J Bacteriol. 2015
Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death
Keatinge M, Bui H, Menke A, Chen YC, Sokol AM, Bai Q, Ellett F, Da Costa M, Burke D, Gegg M, Trollope L, Payne T, McTighe A, Mortiboys H, de Jager S, Nuthall H, Kuo MS, Fleming A, Schapira AH, Renshaw SA, Highley JR, Chacinska A, Panula P, Burton EA, O'Neill MJ, Bandmann O
Hum Mol Genet. 2015
Non-catalytic N-terminal domain negatively influences the nucleotide exchange activity of translation elongation factor 1Bα
Trosiuk TV, Shalak VF, Szczepanowski RH , Negrutskii BS, El'skaya AV
FEBS J. 2015
A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation
Zhao H, Ghirlando R, Alfonso C, Arisaka F, Attali I, Bain DL, Bakhtina MM, Becker DF, Bedwell GJ, Bekdemir A, Besong TM, Birck C, Brautigam CA, Brennerman W, Byron O, Bzowska A, Chaires JB, Chaton CT, Cölfen H, Connaghan KD, Crowley KA, Curth U, Daviter T, Dean WL, Díez AI, Ebel C, Eckert DM, Eisele LE, Eisenstein E, England P, Escalante C, Fagan JA, ... Szczepanowski RH,.. Schuck P
PLoS One. 2015
Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture
Esteves da Silva M, Adrian M, Schätzle P, Lipka J, Watanabe T, Cho S, Futai K, Wierenga CJ, Kapitein LC, Hoogenraad CC
Cell Rep. 2015
The oxidation status of Mic19 regulates MICOS assembly
Sakowska P, Jans DC, Mohanraj K, Riedel D, Jakobs S, Chacinska A
Mol Cell Biol. 2015
Tuberous sclerosis complex neuropathology requires glutamate-cysteine ligase
Malik AR, Liszewska E, Skalecka A, Urbanska M, Iyer AM, Swiech LJ, Perycz M, Parobczak K, Pietruszka P, Zarebska MM, Macias M, Kotulska K, Borkowska J, Grajkowska W, Tyburczy ME, Jozwiak S, Kwiatkowski DJ, Aronica E, Jaworski J
Acta Neuropathol Commun. 2015
Matricellular proteins of the Cyr61/CTGF/NOV (CCN) family and the nervous system
Malik AR, Liszewska E, Jaworski J
Front Cell Neurosci. 2015
Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3βMistargeted mitochondrial proteins activate a proteostatic response in the cytosol
Cymerman IA, Gozdz A, Urbanska M, Milek J, Dziembowska M, Jaworski J
PLoS One. 2015
APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription
Banach-Orlowska M, Szymanska E, Miaczynska M
FEBS Lett. 2015
Endocytic adaptor protein Tollip inhibits canonical Wnt signaling
Torun A, Szymańska E, Castanon I, Wolińska-Nizioł L, Bartosik A, Jastrzębski K, Miętkowska M, González-Gaitán M, Miaczynska M
PLoS One. 2015
Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol
Wrobel L, Topf U, Bragoszewski P , Wiese S, Sztolsztener ME , Oeljeklaus S, Varabyova A, Lirski M, Chroscicki P, Mroczek S, Januszewicz E, Dziembowski A, Koblowska M, Warscheid B, Chacinska A
Nature. 2015
A Kinase Anchoring Protein 9 Is a Novel Myosin VI Binding Partner That Links Myosin VI with the PKA Pathway in Myogenic Cells
Karolczak J, Sobczak M, Skowronek K, Rędowicz MJ
Biomed Res Int.. 2015
Helicobacter pylori HP0377, a member of the Dsb family, is an untypical multifunctional CcmG that cooperates with dimeric thioldisulfide oxidase HP0231
Roszczenko P, Grzeszczuk M, Kobierecka P, Wywial E, Urbanowicz P, Wincek P, Nowak E, Jagusztyn-Krynicka EK
BMC Microbiol.. 2015
Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment
Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K, Rominger A
Mol Psychiatry.. 2015
Retro-translocation of mitochondrial intermembrane space proteins
Bragoszewski P, Wasilewski M, Sakowska P, Gornicka A, Böttinger L, Qiu J, Wiedemann N, Chacinska A
Proc Natl Acad Sci U S A. 2015
Cox17 is an auxiliary factor involved in the control of the mitochondrial contact site and cristae organizing system
Chojnacka M, Gornicka A, Oeljeklaus S, Warscheid B, Chacinska A
J Biol Chem. 2015
Mitochondrial translocation of APE1 relies on the MIA pathway
Barchiesi A, Wasilewski M, Chacinska A, Tell G, Vascotto C
Nucleic Acids Res. 2015
Social and Economic Correlates of Malnutrition in Polish Elderly Population: The Results of PolSenior Study
Krzymińska-Siemaszko R, Mossakowska M, Skalska A, Klich-Rączka A, Tobis S, Szybalska A, Cylkowska-Nowak M, Olszanecka-Glinianowicz M, Chudek J, Wieczorowska-Tobis K.
J Nutr Health Aging. 2015
Inflammation but not obesity or insulin resistance is associated with increased plasma fibroblast growth factor 23 concentration in the elderly
Holecki M, Jerzy C, Owczarek A, Olszanecka-Glinianowicz M, Bożentowicz-Wikarek M, Duława J, Mossakowska M, Zdrojewski T, Skalska A, Więcek A
Clin Endocrinol (Oxf).. 2015
Association between vitamin D concentration and levels of sex hormones in an elderly Polish population with different genotypes of VDR polymorphisms (rs10735810, rs1544410, rs7975232, rs731236)
Laczmanski L, Lwow F, Mossakowska M, Puzianowska-Kuznicka M, Szwed M, Kolackov K, Krzyzanowska-Swiniarska B, Bar-Andziak E, Chudek J, Sloka N, Milewicz A
Gene.. 2015
Plasma fibroblast growth factor 23 concentration and iron status. Does the relationship exist in the elderly population?
Bożentowicz-Wikarek M, Kocełak P, Owczarek A, Olszanecka-Glinianowicz M, Mossakowska M, Skalska A, Więcek A, Chudek J
Clin Biochem. 2015
Plasma visfatin/nicotinamide phosphoribosyltransferase levels in hypertensive elderly - results from the PolSenior substudy.
Kocelak P, Olszanecka-Glinianowicz M, Owczarek A, Bożentowicz-Wikarek M, Brzozowska A, Mossakowska M, Zdrojewski T, Grodzicki T, Więcek A, Chudek J.
J Am Soc Hypertens. 2015
Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease
Gaur V, Wyatt HDM, Komorowska W, Szczepanowski RH, de Sanctis D, Gorecka KM, West SC, Nowotny M
Cell Reports. 2015
2-Thiouracil deprived of thiocarbonyl function preferentially base pairs with guanine rather than adenine in RNA and DNA duplexes
Sochacka E, Szczepanowski RH, Cypryk M, Sobczak M, Janicka M, Kraszewska K, Bartos P, Chwialkowska A, Nawrot B
Nucleic Acids Res. 2015
Dimerization and phosphatase activity of calcyclin-binding protein/Siah-1 interacting protein: the influence of oxidative stress
Topolska-Woś AM, Shell SM, Kilańczyk E, Szczepanowski RH, Chazin WJ, Filipek A
FASEB J.. 2015
Changing Faces of Transcriptional Regulation Reflected by Zic3
Winata CL, Kondrychyn I, Korzh V
Current Genomics. 2015
Paraoxonase 1 activity and level of antibodies directed against oxidized low density lipoproteins in a group of an elderly population in Poland - PolSenior study.
Bednarska-Makaruk M, Rodo M, Szirkowiec W, Mossakowska M, Puzianowska-Kuźnicka M, Skalska A, Zdrojewski T, Ryglewicz D, Wehr H
Arch Gerontol Geriatr.. 2015
Socioeconomic profile of elderly Polish men treated for benign prostate hyperplasia: Results of the population-based PolSenior study
Prajsner A, Chudek J, Szybalska A, Piotrowicz K, Zejda J, Więcek A, PolSenior Study Group
European Geriatric Medicine. 2015
A Common Copy Number Variation Polymorphism in the CNTNAP2 Gene: Sexual Dimorphism in Association with Healthy Aging and Disease
Iakoubov L, Mossakowska M, Szwed M, Puzianowska-Kuznicka M
Gerontology. 2015
Missense variant in CCDC22 causes X-linked recessive intellectual disability with features of Ritscher-Schinzel/3C syndrome
Kolanczyk M, Krawitz P, Hecht J, Hupalowska A, Miaczynska M, Marschner K, Schlack C, Emerich D, Kobus K, Kornak U, Robinson PN, Plecko B, Grangl G, Uhrig S, Mundlos S, Horn D
Eur J Hum Genet. 2015
Age-related changes of leptin and leptin receptor variants in healthy elderly and long-lived adults
Roszkowska-Gancarz M, Jonas M, Owczarz M , Kurylowicz A, Polosak J, Franek E, Slusarczyk P, Mossakowska M, Puzianowska-Kuznicka M
Geriatr Gerontol Int. 2015
High resolution structure of an M23 peptidase with a substrate analogue
Grabowska M, Jagielska E, Czapinska H, Bochtler M, Sabala I
Sci Rep. 2015
2014
Crystal structure of RNase H3-substrate complex reveals parallel evolution of RNA/DNA hybrid recognition.
Figiel M, Nowotny M.
Nucleic Acids Res.. 2014
Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression.
Mathys H, Basquin J, Ozgur S, Czarnocki-Cieciura M, Bonneau F, Aartse A, Dziembowski A, Nowotny M, Conti E, Filipowicz W.
Mol Cell.. 2014
Distribution and frequencies of post-transcriptional modifications in tRNAs.
Machnicka M, Olchowik A, Grosjean H, Bujnicki JM.
RNA Biol.. 2014
RNA methyltransferases involved in 5' cap biosynthesis.
Byszewska M, Smietanski M, Purta E, Bujnicki JM.
RNA Biol.. 2014
Carboxy terminus of GATA4 transcription factor is required for its cardiogenic activity and interaction with CDK4
Gallagher JM, Yamak A, Kirilenko P, Black S, Bochtler M, Lefebvre C, Nemer M, Latinkić BV
Mech Dev. 2014
Ocena sprawności funkcjonalnej warszawskich stulatków w zakresie podstawowych czynności życia codziennego – wyniki wstępne
Skubiszewska A, Wodzyńska K, Szybalska A, Ślusarczyk P, Broczek K, Puzianowska-Kuźnicka M, Olędzka G, Mossakowska M
Gerontologia Polska. 2014
Cellular control of cortical actin nucleation
Bovellan M, Romeo Y, Biro M, Boden A, Chugh P, Yonis A, Vaghela M, Fritzsche M, Moulding D, Thorogate R, Jégou A, Thrasher AJ, Romet-Lemonne G, Roux PP, Paluch EK, Charras G
Curr Biol. 2014
Mgr2 functions as lateral gatekeeper for preprotein sorting in the mitochondrial inner membrane
Ieva R, Schrempp SG, Opaliński L Wollweber F, Höß P, Heißwolf AK, Gebert M, Zhang Y, Guiard B, Rospert S, Becker T, Chacinska A, Pfanner N, van der Laan M
Mol Cell.. 2014
Identification of tetrahydrocarbazoles as novel multifactorial drug candidates for treatment of Alzheimer's disease
Honarnejad K, Daschner A, Gehring AP, Szybinska A, Giese A, Kuznicki J, Bracher F, Herms J
Transl Psychiatry.. 2014
Designability landscape reveals sequence features that define axial helix rotation in four-helical homo-oligomeric antiparallel coiled-coil structures
Szczepaniak K, Lach G, Bujnicki JM, Dunin-Horkawicz S
J Struct Biol.. 2014
Functional and bioinformatics analysis of two Campylobacter jejuni homologs of the thiol-disulfide oxidoreductase, DsbA
Grabowska AD, Wywiał E, Dunin-Horkawicz S , Lasica AM, Wösten MM, Nagy-Staroń A, Godlewska R, Bocian-Ostrzycka K, Pieńkowska K, Laniewski P, Bujnicki JM, van Putten JP, Jagusztyn-Krynicka EK
PLoS One.. 2014
ClaRNA: a classifier of contacts in RNA 3D structures based on a comparative analysis of various classification schemes
Walen T, Chojnowski G, Gierski P,Bujnicki JM,
Nucleic Acids Res.. 2014
Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2
Ramos-Molina B, Lambertos A, Lopez-Contreras AJ, Kasprzak JM, Czerwoniec A, Bujnicki JM, Cremades A, Penafiel R
FEBS Open Bio.. 2014
Female-specific gene expression in dioecious liverwort Pellia endiviifolia is developmentally regulated and connected to archegonia production
Sierocka I, Kozlowski LP, Bujnicki JM, Jarmolowski A, Szweykowska-Kulinska Z
BMC Plant Biol.. 2014
Computational modeling of RNA 3D structures, with the aid of experimental restraints
Magnus M, Matelska D, Lach G, Chojnowski G, Boniecki MJ, Purta E, Dawson W, Dunin-Horkawicz S, Bujnicki JM
RNA Biol.. 2014
Automated modeling of RNA 3D structure
Rother K, Rother M, Skiba P, Bujnicki JM
Methods Mol Biol. 2014
Crystal structure of the catalytic core of Rad2: insights into the mechanism of substrate binding
Miętus M, Nowak E, Jaciuk M, Kustosz P, Studnicka J, Nowotny M
Nucleic Acids Res. 2014
A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria
Gornicka A, Bragoszewski P, Chroscicki P, Wenz LS, Schulz C, Rehling P, Chacinska A
Mol Biol Cell. 2014
Recent advances in primary ciliary dyskinesia genetics
Kurkowiak M, Ziętkiewicz E, Witt M
J Med Genet. 2014
Presequence recognition by the tom40 channel contributes to precursor translocation into the mitochondrial matrix
Melin J, Schulz C, Wrobel L, Bernhard O, Chacinska A, Jahn O, Schmidt B, Rehling P
Mol Cell Biol. 2014
Mitochondrial protein translocases for survival and wellbeing
Sokol AM, Sztolsztener ME, Wasilewski M, Heinz E, Chacinska A
FEBS Lett. 2014
Reduced functionality in everyday activities of patients with self-reported heart failure hospitalization - Population-based study results
Skalska A, Wizner B, Więcek A, Zdrojewski T, Chudek J, Klich-Rączka A, Piotrowicz K, Błędowski P, Mossakowska M, Michel JP, Grodzicki T
Int J Cardiol. 2014
Relationship between circulating visfatin/NAMPT, nutritional status and insulin resistance in an elderly population - results from the PolSenior substudy
Olszanecka-Glinianowicz M, Owczarek A, Bożentowicz-Wikarek M, Brzozowska A, Mossakowska M, Zdrojewski T, Grodzicki T, Więcek A, Chudek J
Metabolism. 2014
Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans
Sabala I, Jagielska E, Bardelang PT, Czapinska H, Dahms SO, Sharpe JA, James R, Than ME, Thomas NR, Bochtler M
FEBS J. 2014
Structural basis of the methylation specificity of R.DpnI
Mierzejewska K, Siwek W, Czapinska H, Kaus-Drobek M, Radlinska M, Skowronek K, Bujnicki JM, Dadlez M, Bochtler M
Nucleic Acids Res.. 2014
Insights into DNA hydroxymethylation in the honeybee from in-depth analyses of TET dioxygenase
Wojciechowski M, Rafalski D, Kucharski R, Misztal K, Maleszka J, Bochtler M, Maleszka R
Open Biol. 2014
Cognitive flexibility and long-term depression (LTD) are impaired following β-catenin stabilization in vivo
Mills F, Bartlett TE, Dissing-Olesen L, Wisniewska MB, Kuznicki J, Macvicar BA, Wang YT, Bamji SX
Proc Natl Acad Sci U S A.. 2014
The assessment of cognitive impairment suspected of dementia in Polish elderly people: results of the population-based PolSenior Study
Klich-Rączka A, Piotrowicz K, Mossakowska M, Skalska A, Wizner B, Broczek K, Wieczorowska-Tobis K, Grodzicki T
Exp Gerontol. 2014
Interrelation between genotypes of the vitamin D receptor gene and serum sex hormone concentrations in the Polish elderly population: the PolSenior study
Laczmanski L, Milewicz A, Puzianowska-Kuznicka M, Lwow F, Kolackov K, Mieszczanowicz U, Pawlak M, Krzyzanowska-Swiniarska B, Bar-Andziak E, Chudek J, Mossakowska M
Exp Gerontol. 2014
Secondary prevention of stroke in elderly people in Poland-Results of PolSenior study
Labuz-Roszak B, Skrzypek M, Pierzchała K, Machowska-Majchrzak A, Mossakowska M, Chudek J, Mańka-Gaca I, Bartman W, Więcek A
Neurol Neurochir Pol. 2014
Fibroblast growth factor 23 (FGF23) and early chronic kidney disease in the elderly
Chudek J, Kocełak P, Owczarek A, Bozentowicz-Wikarek M, Mossakowska M, Olszanecka-Glinianowicz M, Wiecek A
Nephrol Dial Transplant. 2014
Functional polymorphisms of the leptin and leptin receptor genes are associated with longevity and with the risk of myocardial infarction and of type 2 diabetes mellitus
Roszkowska-Gancarz M, Kurylowicz A, Polosak J, Mossakowska M, Franek E, Puzianowska-Kuźnicka M
Endokrynol Pol. 2014
The RNase H-like superfamily: new members, comparative structural analysis and evolutionary classification
Majorek KA, Dunin-Horkawicz S, Steczkiewicz K, Muszewska A, Nowotny M, Ginalski K, Bujnicki JM
Nucleic Acids Res.. 2014
Uniform nomenclature for the mitochondrial contact site and cristae organizing system
Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J
J Cell Biol.. 2014
Potassium channel in the mitochondria of human keratinocytes
Toczyłowska-Mamińska R, Olszewska A, Laskowski M, Bednarczyk P, Skowronek K, Szewczyk A
J Invest Dermatol. 2014
Labeling of platelet-derived growth factor by reversible biotinylation to visualize its endocytosis by microscopy
Sadowski Ł, Jastrzębski K, Purta E, Hellberg C, Miaczynska M
Methods Enzymol.. 2014
Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target
Tomecki R, Drazkowska K, Kucinski I, Stodus K, Szczesny RJ, Gruchota J, Owczarek EP, Kalisiak K, Dziembowski A
Nucleic Acids Res.. 2014
New simple efficient algorithms computing powers and runs in strings
Crochemore M, Iliopoulos CS, Kubica M, Radoszewski J, Rytter W, Stencel K, Walen T
Discrete Applied Mathematics. 2014
Crystal structure of the 5hmC specific endonuclease PvuRts1I
Kazrani AA, Kowalska M, Czapinska H, Bochtler M
Nucleic Acids Res.. 2014
CFTR Mutations Spectrum and the Efficiency of Molecular Diagnostics in Polish Cystic Fibrosis Patients
Ziętkiewicz E, Rutkiewicz E, Pogorzelski A, Klimek B, Voelkel K, Witt M
PLoS One. 2014
Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry
Nowak E, Miller JT, Bona MK, Studnicka J, Szczepanowski RH, Jurkowski J, Le Grice SFJ, Nowotny M
Nature Structural & Molecular Biology. 2014
Patterns of structural dynamics in RACK1 protein retained throughout evolution: A hydrogen-deuterium exchange study of three orthologs
Tarnowski K, Fituch K, Szczepanowski RH, Dadlez M, Kaus-Drobek M
Protein Sci. 2014
The GRIP1/14-3-3 Pathway Coordinates Cargo Trafficking and Dendrite Development
Geiger JC, Lipka J, Segura I, Hoyer S, Schlager MA, Wulf PS, Weinges S, Demmers J, Hoogenraad CC, Acker-Palmer A
Dev Cell. 2014
Cognitive Performance and Functional Status Are the Major Factors Predicting Survival of Centenarians in Poland
Mossakowska M , Broczek K, Wieczorowska-Tobis K, Klich-Raczka A, Jonas M, Pawlik-Pachucka E, Safranow K, Kuznicki J , Puzianowska-Kuznicka M
J Gerontol A Biol Sci Med Sci. 2014
Ciliary genes are down-regulated in bronchial tissue of primary ciliary dyskinesia patients
Geremek M, Ziętkiewicz E, Bruinenberg M, Franke L, Pogorzelski A, Wijmenga C, Witt M
PLoS One. 2014
Structural analysis of human 2′-O-ribose methyltransferases involved in mRNA cap structure formation
Smietanski M, Werner M, Purta E, Kaminska KH, Stepinski J, Darzynkiewicz E, Nowotny M, Bujnicki JM
Nat Commun. 2014
RNA Bricks - a database of RNA 3D motifs and their interactions
Chojnowski G, Walen T, Bujnicki JM
Nucleic Acids Res.. 2014
Solution conformation of Adenovirus Virus Associated RNA-I and its interaction with PKR
Dzananovic E, Patel TR, Chojnowski G, Boniecki MJ, Deo S, McEleney K, Harding SE, Bujnicki JM, McKenna SA
J Struct Biol. 2014
Novel Highly Thermostable Endolysin from Thermus scotoductus MAT2119 Bacteriophage Ph2119 with Amino Acid Sequence Similarity to Eukaryotic Peptidoglycan Recognition Proteins
Plotka M, Kaczorowska AK, Stefanska A, Morzywolek A, Fridjonsson OH, Dunin-Horkawicz S, Kozlowski L, Hreggvidsson GO, Kristjansson JK, Dabrowski S, Bujnicki JM, Kaczorowski T
Appl Environ Microbiol. 2014
Computational modeling of protein-RNA complex structures
Tuszynska I, Matelska D, Magnus M, Chojnowski G, Kasprzak JM, Kozlowski LP, Dunin-Horkawicz S, Bujnicki JM
Methods. 2014
NMR structural studies of the first catalytic half-domain of ubiquitin activating enzyme
Jaremko M, Jaremko L, Nowakowski M, Wojciechowski M, Szczepanowski RH, Panecka R, Zhukov I, Bochtler M, Ejchart A
J Struct Biol. 2014
CD44 regulates dendrite morphogenesis through Src tyrosine kinase-dependent positioning of the Golgi
Skupien A, Konopka A, Trzaskoma P, Labus J, Gorlewicz A, Swiech L, Babraj M, Dolezyczek H, Figiel I, Ponimaskin E, Wlodarczyk J, Jaworski J, Wilczynski GM, Dzwonek J
J Cell Sci. 2014
2013
Dietary intakes of iron and zinc assessed in a selected group of the elderly: are they adequate
Madej D, Borowska K, Bylinowska J, Szybalska A, Pietruszka B
Rocz Panstw Zakl Hig. 2013
Why do we need induced pluripotent stem cells in neurobiology?
Liszewska E, Jaworski J
Postepy Biochem. 2013
Rational design of helical nanotubes from self-assembly of coiled-coil lock washers
Xu C, Liu R, Mehta AK, Guerrero-Ferreira RC, Wright ER, Dunin-Horkawicz S, Morris K, Serpell LC, Zuo X, Wall JS, Conticello VP
J Am Chem Soc.. 2013
Crystal structure of RuvC resolvase in complex with Holliday junction substrate
Górecka KM, Komorowska W, Nowotny M
Nucleic Acids Res. 2013
Cell cortex composition and homeostasis resolved by integrating proteomics and quantitative imaging
Biro M, Romeo Y, Kroschwald S, Bovellan M, Boden A, Tcherkezian J, Roux PP, Charras G, Paluch EK
Cytoskeleton (Hoboken). 2013
Isolation of monomeric photosystem II that retains the subunit PsbS
Haniewicz P, De Sanctis D, Büchel C, Schröder WP, Loi MC, Kieselbach T, Bochtler M, Piano D
Photosynth Res. 2013
LigandRNA: computational predictor of RNA-ligand interactions
Philips A, Milanowska K, Lach G, Bujnicki JM
RNA. 2013
Caveolin-1 - a novel interacting partner of organic cation/carnitine transporter (octn2): effect of protein kinase C on this interaction in rat astrocytes.
Czeredys M, Samluk L, Michalec K, Tułodziecka K, Skowronek K, Nałęcz KA
PLoS One. 2013
Telomere Length in Elderly Caucasians Weakly Correlates with Blood Cell Counts
Gutmajster E, Witecka J, Wyskida M, Koscinska-Marczewska J, Szwed M, Owczarz M, Mossakowska M, Milewicz A, Puzianowska-Kuznicka M, Zejda J, Wiecek A, Chudek J, Sieron A.L
The Scientific World Journal. 2013
Development and Implementation of a High-Throughput Compound Screening Assay for Targeting Disrupted ER Calcium Homeostasis in Alzheimer's Disease
Honarnejad K, Daschner A, Giese A, Zall A, Schmidt B, Szybinska A, Kuznicki J, Herms J
PLoS One. 2013
Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington’s disease
Czeredys M, Gruszczynska-Biegala J, Schacht T, Methner A, Kuznicki J
Front. Mol. Neurosci. 2013
Mutations in cytoplasmic dynein and its regulators cause malformations of cortical development and neurodegenerative diseases
Lipka J, Kuijpers M,Jaworski J, Hoogenraad CC
Biochem Soc Trans. 2013
FRET-Based Calcium Imaging: A Tool for High-Throughput/Content Phenotypic Drug Screening in Alzheimer Disease
Honarnejad K, Kirsch AK, Daschner A, Szybinska A, Kuznicki J, Herms J
J Biomol Screen. 2013
The fragile x mental retardation protein regulates matrix metalloproteinase 9 mRNA at synapses
Janusz A, Milek J, Perycz M, Pacini L, Bagni C, Kaczmarek L, Dziembowska M
J Neurosci. 2013
A Common Copy Number Variation (CNV) Polymorphism in the CNTNAP4 Gene: Association with Aging in Females
Iakoubov L, Mossakowska M, Szwed M, Duan Z, Sesti F, Puzianowska-Kuznicka M
PLoS One. 2013
Effects of membrane trafficking on signaling by receptor tyrosine kinases
Miaczynska M
Cold Spring Harb Perspect Biol.. 2013
Native STIM2 and ORAI1 proteins form a calcium-sensitive and thapsigargin-insensitive complex in cortical neurons
Gruszczynska-Biegala J, Kuznicki J
J Neurochem. 2013
Adhesion, but not a specific cadherin code, is indispensable for ES cell and induced pluripotency
Bedzhov I, Alotaibi H, Basilicata MF, Ahlborn K,Liszewska E, Brabletz T, Stemmler MP
Stem Cell Res. 2013
S6:S18 ribosomal protein complex interacts with a structural motif present in its own mRNA
Matelska D, Purta E, Panek S, Boniecki MJ, Bujnicki JM, Dunin-Horkawicz S
RNA. 2013
Cross-linked glucose oxidase clusters for biofuel cell anode catalysts
Dudzik J, Chang WC, Kannan AM, Filipek S, Viswanathan S, Li P, Renugopalakrishnan V, Audette GF
Biofabrication. 2013
Enhancing the production of galacto-oligosaccharides by mutagenesis of Sulfolobus solfataricus β-galactosidase
Wu Y, Yuan S, Chen S, Wu D, Chen J, Wu J
Food Chem. 2013
A linear time algorithm for consecutive permutation pattern matching
Kubica M, Kulczyńskia T, Radoszewskia J, Rytter W,Walen T
Information Processing Letters. 2013
Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain
Bednarczyk P, Wieckowski MR, Broszkiewicz M, Skowronek K, Siemen D, Szewczyk A
PLoS One. 2013
Low-temperature molecular dynamics simulations of horse heart cytochrome c and comparison with inelastic neutron scattering data
Pulawski W, Filipek S, Zwolinska A, Debinski A, Krzysko K, Garduño-Juárez R, Viswanathan S, Renugopalakrishnan V
Eur Biophys J. 2013
RNase H2 roles in genome integrity revealed by unlinking its activities
Chon H, Sparks JL, Rychlik M, Nowotny M, Burgers PM, Crouch RJ, Cerritelli SM
Nucleic Acids Res. 2013
A note on efficient computation of all Abelian periods in a string
Crochemore M, Iliopoulos C.S, Kociumaka T, Kubica M, Pachocki J, Radoszewski J, Rytter W,Tyczyński W, Waleń T
Information Processing Letters. 2013
Towards Improved Quality of GPCR Models by Usage of Multiple Templates and Profile-Profile Comparison
Latek D, Pasznik P, Carlomagno T, Filipek S
PLoS One. 2013
Alzheimer's disease modeling: ups, downs, and perspectives for human induced pluripotent stem cells
Wojda U, Kuznicki J
J Alzheimers Dis. 2013
Cell adhesion mechanics of zebrafish gastrulation
Maître JL, Berthoumieux H, Gabriel Krens SF, Salbreux G, Jülicher F, Paluch E, Heisenberg CP
M S-MEDECINE SCIENCES. 2013
Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation
Qiu J, Wenz LS, Zerbes RM, Oeljeklaus S, Bohnert M, Stroud DA, Wirth C, Ellenrieder L, Thornton N, Kutik S, Wiese S, Schulze-Specking A, Zufall N, Chacinska A, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N, Wiedemann N, Becker T
Cell. 2013
Mia40 and MINOS act in parallel with Ccs1 in the biogenesis of mitochondrial Sod1
Varabyova A, Topf U, Kwiatkowska P, Wrobel L, Kaus-Drobek M, Chacinska A
FEBS J. 2013
QA-RecombineIt: a server for quality assessment and recombination of protein models
Pawlowski M, Bogdanowicz A, Bujnicki JM
Nucleic Acids Res. 2013
RNAlyzer--novel approach for quality analysis of RNA structural models
Lukasiak P, Antczak M, Ratajczak T, Bujnicki JM, Szachniuk M, Adamiak RW, Popenda M, Blazewicz J
Nucleic Acids Res. 2013
CompaRNA: a server for continuous benchmarking of automated methods for RNA secondary structure prediction
Puton T, Kozlowski LP, Rother KM, Bujnicki JM
Nucleic Acids Res.. 2013
Plasma level of N-terminal pro brain natriuretic peptide (NT-proBNP) in elderly population in Poland - the PolSenior Study
Nadrowski P, Chudek J, Grodzicki T, Mossakowska M, Skrzypek M, Wiecek A, Zdrojewski T, Kozakiewicz K
Exp Gerontol.. 2013
The prion protein M129V polymorphism: Longevity and cognitive impairment among Polish centenarians
Golanska E, Sieruta M, Corder E, Gresner SM, Pfeffer A, Chodakowska-Zebrowska M, Sobow TM, Klich I, Mossakowska M, Szybinska A, Barcikowska M, Liberski PP
Prion. 2013
Spatiotemporal Characterization of mTOR Kinase Activity Following Kainic Acid Induced Status Epilepticus and Analysis of Rat Brain Response to Chronic Rapamycin Treatment
Macias M, Blazejczyk M, Kazmierska P, Caban B, Skalecka A, Tarkowski B, Rodo A, Konopacki J, Jaworski J
PLoS One. 2013
Myosin-V Opposes Microtubule-Based Cargo Transport and Drives Directional Motility on Cortical Actin
Kapitein LC, van Bergeijk P, Lipka J, Keijzer N, Wulf PS, Katrukha EA, Akhmanova A, Hoogenraad CC
Curr Biol. 2013
Dynamin Inhibitors Impair Endocytosis and Mitogenic Signaling of PDGF
Sadowski L, Jastrzębski K, Kalaidzidis Y, Heldin CH, Hellberg C, Miaczynska M
Traffic. 2013
The ubiquitin-proteasome system regulates mitochondrial intermembrane space proteins
Bragoszewski P, Gornicka A, Sztolsztener ME, Chacinska A
Mol Cell Biol. 2013
Brain-derived neurotrophic factor induces matrix metalloproteinase-9 expression in neurons via serum response factor/c-Fos pathway
Kuzniewska B, Rejmak E, Malik AR, Jaworski J, Kaczmarek L, Kalita K
Mol Cell Biol. 2013
TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites
van Spronsen M, Mikhaylova M, Lipka J, Schlager MA, van den Heuvel DJ, Kuijpers M, Wulf PS, Keijzer N, Demmers J, Kapitein LC, Jaarsma D, Gerritsen HC, Akhmanova A, Hoogenraad CC
Neuron. 2013
Analysis of calcium homeostasis in fresh lymphocytes from patients with sporadic Alzheimer's disease or mild cognitive impairment
Jaworska A, Dzbek J, Styczynska M, Kuznicki J
Biochim Biophys Acta. 2013
Assessment of adiponectin and its isoforms in Polish centenarians
Bik W, Baranowska-Bik A, Wolinska-Witort E, Kalisz M, Broczek K, Mossakowska M, Baranowska B
Exp Gerontol. 2013
APBB2 genetic polymorphisms are associated with severe cognitive impairment in centenarians
Golanska E, Sieruta M, Gresner SM, Pfeffer A, Chodakowska-Zebrowska M, Sobow TM, Klich I, Mossakowska M, Szybinska A, Barcikowska M, Liberski PP
Exp Gerontol. 2013
Physiological Role of β-Catenin/TCF Signaling in Neurons of the Adult Brain
Wisniewska MB
Neurochem Res. 2013
Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid
Nowak E, Potrzebowski W, Konarev PV, Rausch JW, Bona MK, Svergun DI, Bujnicki JM, Le Grice SF, Nowotny M
Nucleic Acids Res. 2013
CYR61, a matricellular protein, is needed for dendritic arborization of hippocampal neurons
Malik AR, Urbanska M, Gozdz A, Swiech LJ, Nagalski A, Perycz M, Blazejczyk M, Jaworski J
J Biol Chem. 2013
Mitochondrial protein import: Mia40 facilitates Tim22 translocation into the inner membrane of mitochondria
Wrobel L, Trojanowska A, Sztolsztener ME, Chacinska A
Mol Biol Cell. 2013
Hsp90 and its co-chaperone, Sgt1, as autoantigens in dilated cardiomyopathy
Kapustian LL, Vigontina OA, Rozhko OT, Ryabenko DV, Michowski W, Lesniak W, Filipek A, Kroupskaya IV, Sidorik LL
Heart Vessels. 2013
Total and high molecular weight adiponectin and level-modifying polymorphisms of ADIPOQ in centenarians
Roszkowska-Gancarz M, Bartoszewicz Z, Polosak J, Kurylowicz A, Jonas M, Mossakowska M, Franek E, Puzianowska-Kuźnicka M
Endokrynologia Polska. 2013
Beyond control of protein translation: What we have learned about the non-canonical regulation and function of mammalian target of rapamycin (mTOR)
Malik AR, Urbanska M, Macias M, Skalecka A, Jaworski J
Biochim Biophys Acta. 2013
Downregulation of extracellular signal-regulated kinase 1/2 activity by calmodulin KII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer's disease patients
Esteras N, Alquézar C, Bermejo-Pareja F, Bialopiotrowicz E, Wojda U, Martín-Requero A
Neurobiol Aging. 2013
RNApathwaysDB – a database of RNA maturation and decay pathways
Milanowska K, Mikolajczak K, Lukasik A, Skorupski M, Balcer Z, Machnicka MA, Nowacka M, Rother KM, Bujnicki JM
Nucleic Acids Res. 2013
MODOMICS: a database of RNA modification pathways: 2013 update
Machnicka MA, Milanowska K, Osman Oglou O, Purta E, Kurkowska M, Olchowik A, Januszewski W, Kalinowski S, Dunin-Horkawicz S, Rother KM, Helm M, Bujnicki JM, Grosjean H
Nucleic Acids Res. 2013
Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain
Nagalski A, Irimia M, Szewczyk L, Ferran JL, Misztal K, Kuznicki J, Wisniewska MB
Brain Struct Funct. 2013
CpG Underrepresentation and the Bacterial CpG Specific DNA Methyltransferase M.MpeI
Wojciechowski M, Czapinska H, Bochtler M
Proc Natl Acad Sci U S A.. 2013
Disulfide bond formation: sulfhydryl oxidase ALR controls mitochondrial biogenesis of human MIA40
Sztolsztener ME, Brewinska A, Guiard B, Chacinska A
Traffic. 2013
Multifunctional protein APPL2 contributes to survival of human glioma cells
Pyrzynska B, Banach-Orlowska M, Teperek-Tkacz M, Miekus K, Drabik G, Majka M, Miaczynska M
Mol Oncol.. 2013
BCL11B, FLT3, NOTCH1 and FBXW7 mutation status in T-cell Acute Lymphoblastic Leukemia patients
Kraszewska MD, Dawidowska M, Kosmalska M, Sędek Ł, Grzeszczak W, Kowalczyk JR, Szczepański T, Witt M
Blood Cells, Molecules and Diseases. 2013
2012
The Prevalence of Dementia in Warsaw Centenarians: a Population – Based Study
Pfeffer A, Chodakowska M, Czyżewski K, Gabryelewicz T, Łuczywek Ł, Mossakowska M, Broczek K, Barcikowska M
Postępy Nauk Medycznych. 2012
Structure prediction of alternatively spliced proteins In „Alternative pre-mRNA Splicing: Theory and Protocols: The Complete Guide for Biomedical Scientists”
Kozlowski L, Orlowski J, Bujnicki JM
. 2012
Template-based and template-free modeling of RNA 3D structure: inspirations from protein structure modeling.
Rother K, Rother M, Boniecki M, Puton T, Tomala K, Lukasz P, Bujnicki JM.
RNA 3D Structure Analysis and Prediction. 2012
Ubiquitous amyloids
Pulawski W, Ghoshdastider U, Andrisano V, Filipek S
Appl Biochem Biotechnol. 2012
MetaDisorder: A meta-server for the prediction of intrinsic disorder in proteins
Kozlowski LP, Bujnicki JM
BMC Bioinformatics. 2012
Molecular evolution of dihydrouridine synthases
Kasprzak JM, Czerwoniec A, Bujnicki JM
BMC Bioinformatics. 2012
Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage
Kusio-Kobialka M, Wolanin K, Podszywalow-Bartnicka P, Sikora E, Skowronek K, McKenna SL, Ghizzoni M, Dekker FJ, Piwocka K
Apoptosis. 2012
A novel insight into the oxidoreductase activity of Helicobacter pylori HP0231 protein
Roszczenko P, Radomska KA, Wywial E, Collet JF, Jagusztyn-Krynicka EK
PLoS One. 2012
A novel homozygous p.Arg527Leu LMNA mutation in two unrelated egyptian families causes overlapping mandibuloacral dysplasia and progeria syndrome
Al-Haggar M, Madej-Pilarczyk A, Kozlowski L, Bujnicki JM, Yahia S, Abdel-Hadi D, Shams A, Ahmad N, Hamed S, Puzianowska-Kuznicka M
Eur J Hum Genet. 2012
Amyloid β-Peptide 25-35 Self-Assembly and Its Inhibition: A Model Undecapeptide System to Gain Atomistic and Secondary Structure Details of the Alzheimer's Disease Process and Treatment
Naldi M, Fiori J, Pistolozzi M, Drake AF, Bertucci C, Wu R, Mlynarczyk K, Filipek S, De Simone A, Andrisano V
ACS Chem Neurosci. 2012
The Role of Water in Activation Mechanism of Human N-Formyl Peptide Receptor 1 (FPR1) Based on Molecular Dynamics Simulations
Yuan S, Ghoshdastider U, Trzaskowski B, Latek D, Debinski A, Pulawski W, Wu R, Gerke V, Filipek S
PLoS One. 2012
MetaLocGramN: A meta-predictor of protein subcellular localization for Gram-negative bacteria
Magnus M, Pawlowski M, Bujnicki JM
Biochim Biophys Acta. 2012
Vitamin D receptor gene polymorphism and cardiovascular risk variables in elderly Polish subjects
Laczmanski L, Milewicz A, Lwow F, Puzianowska-Kuznicka M, Pawlak M, Kolackov K, Jedrzejuk D, Krzyzanowska-Swiniarska B, Bar-Andziak E, Chudek J, Mossakowska M
Gynecol Endocrinol. 2012
The prevalence of falls and their relation to visual and hearing impairments among a nation-wide cohort of older Poles
Skalska A, Wizner B, Piotrowicz K, Klich-Rączka A, Klimek E, Mossakowska M, Rowiński R, Kozak-Szkopek E, Jóźwiak A, Gąsowski J, Grodzicki T
Exp Gerontol. 2012
Rational engineering of sequence specificity in R.MwoI restriction endonuclease
Skowronek K, Boniecki MJ, Kluge B, Bujnicki JM
Nucleic Acids Res. 2012
Delineation of structural domains and identification of functionally important residues in DNA repair enzyme Exonuclease VII
Poleszak K, Kaminska KH, Dunin-Horkawicz S, Lupas A, Skowronek KJ, Bujnicki JM
Nucleic Acids Res. 2012
Structural bioinformatics of the human spliceosomal proteome
Korneta I, Magnus M, Bujnicki JM
Nucleic Acids Res. 2012
Novel non-specific DNA adenine methyltransferases
Drozdz M, Piekarowicz A, Bujnicki JM, Radlinska M
Nucleic Acids Res. 2012
Sequence-specific cleavage of the RNA strand in DNA-RNA hybrids by the fusion of ribonuclease H with a zinc finger
Sulej AA, Tuszynska I, Skowronek KJ, Nowotny M, Bujnicki JM
Nucleic Acids Res. 2012
The utility of comparative models and the local model quality for protein crystal structure determination by Molecular Replacement
Pawlowski M, Bujnicki JM
BMC Bioinformatics. 2012
RNAmap2D -- calculation, visualization and analysis of contact and distance maps for RNA and protein-RNA complex structures
Pietal MJ, Szostak N, Rother KM, Bujnicki JM
BMC Bioinformatics. 2012
Molecular Mechanism of Mutant p53 Stabilization: The Role of HSP70 and MDM2
Wiech M, Olszewski MB, Tracz-Gaszewska Z, Wawrzynow B, Zylicz M, Zylicz A
PLoS One. 2012
Novel beta-catenin target genes identified in thalamic neurons encode modulators of neuronal excitability
Wisniewska MB, Nagalski A, Dabrowski M, Misztal K, Kuznicki J
BMC Genomics. 2012
Anti-staphylococcal activities of lysostaphin and LytM catalytic domain
Sabala I, Jonsson IM, Tarkowski A, Bochtler M
BMC Microbiol. 2012
Crystal structure and mechanism of action of the N6-methyladenine dependent type IIM restriction endonuclease
Siwek W, Czapinska H, Bochtler M, Bujnicki JM, Skowronek K
Nucleic Acids Res. 2012
RPGR mutations might cause reduced orientation of respiratory cilia
Bukowy-Bieryłło Z, Ziętkiewicz E, Loges NT, Wittmer M, Geremek M, Olbrich H, Fliegauf M, Voelkel K, Rutkiewicz E, Rutland J, Morgan L, Pogorzelski A, Martin J, Haan E, Berger W, Omran H, Witt M
Pediatr Pulmonol.. 2012
Prenyltransferases Regulate CD20 Protein Levels and Influence Anti-CD20 Monoclonal Antibody-mediated Activation of Complement-dependent Cytotoxicity
Winiarska M, Nowis D, Bil J, Glodkowska-Mrowka E, Muchowicz A, Wanczyk M, Bojarczuk K, Dwojak M, Firczuk M, Wilczek E, Wachowska M, Roszczenko K, Miaczynska M, Chlebowska J, Basak GW, Golab J
J Biol Chem. 2012
In vivo evidence for cooperation of Mia40 and Erv1 in the oxidation of mitochondrial proteins
Böttinger L*, Gornicka A*, Czerwik T, Bragoszewski P, Loniewska-Lwowska A, Schulze-Specking A, Truscott KN, Guiard B, Milenkovic D, Chacinska A, *equally contributing first author
Mol Biol Cell. 2012
Intermembrane space proteome of yeast mitochondria
Voegtle FN, Burkhart JM, Rao S, Gerbeth C, Hinrichs J, Martinou JC, Chacinska A, Sickmann A, Zahedi RP, Meisinger C
Mol Cell Proteomics. 2012
Role of MINOS in protein biogenesis of the mitochondrial outer membrane
Bohnert M, Wenz LS, Zerbes RM, Horvath SE, Stroud DA, von der Malsburg K, Müller JM, Oeljeklaus S, Perschil I, Warscheid B, Chacinska A, Veenhuis M, van der Klei IJ, Daum G, Wiedemann N, Becker T, Pfanner N, van der Laan M
Mol Biol Cell.. 2012
Functional anatomy of neural circuits regulating fear and extinction
Knapska E, Macias M, Mikosz M, Nowak A, Owczarek D, Wawrzyniak M, Pieprzyk M, Cymerman IA, Werka T, Sheng M, Maren S, Jaworski J, Kaczmarek L
Proc. Natl. Acad. Sci.. 2012
Actin cortex mechanics and cellular morphogenesis
Salbreux G, Charras G, Paluch E
Trends Cell Biol.. 2012
Adhesion Functions in Cell Sorting by Mechanically Coupling the Cortices of Adhering Cells
Maître JL, Berthoumieux H, Krens SF, Salbreux G, Jülicher F, Paluch E, Heisenberg CP
Science. 2012
Cell mechanics control rapid transitions between blebs and lamellipodia during migration
Bergert M, Chandradoss SD, Desai RA, Paluch E
Proc Natl Acad Sci U S A. 2012
P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3
Zerrouqi A, Pyrzynska B, Febbraio M, Brat DJ, Van Meir EG
J Clin Invest.. 2012
Alteration of surface properties of dipalmitoyl phosphatidylcholine by benzo[a]pyrene: a model of pulmonary effects of diesel exhaust inhalation
Sosnowski TR, Koliński M, Gradoń L
J Biomed Nanotechnol. 2012
Protein kinase C regulates amino acid transporter ATB
Samluk L, Czeredys M, Skowronek K, Nałęcz KA
Biochem Biophys Res Commun.. 2012
Statins Impair Glucose Uptake in Tumor Cells
Malenda A, Skrobanska A, Issat T, Winiarska M, Bil J, Oleszczak B, Sinski M, Firczuk M, Bujnicki JM, Chlebowska J, Staruch AD, Glodkowska-Mrowka E, Kunikowska J, Krolicki L, Szablewski L, Gaciong Z, Koziak K, Jakobisiak M, Golab J, Nowis DA
Neoplasia. 2012
Crystal structure of 6-SST/6-SFT from Pachysandra terminalis, a plant fructan biosynthesizing enzyme in complex with its acceptor substrate 6-kestose
Lammens W, Le Roy K, Yuan S, Vergauwen R, Rabijns A, Van Laere A, Strelkov SV, Van den Ende W
Plant J.. 2012
Einstein–Hopf drag, Doppler shift of thermal radiation and blackbody drag: Three perspectives on quantum friction
Lach G, DeKievet M, Jentschura UD
Cent. Eur. J. Phys.. 2012
Identification and Regulation of a Molecular Module for Bleb-Based Cell Motility
Goudarzi M, Banisch TU, Mobin MB, Maghelli N, Tarbashevich K, Strate I, van den Berg J, Blaser H, Bandemer S, Paluch E, Bakkers J, Tolić-Nørrelykke IM, Raz E
Dev Cell. 2012
Crystal structures of the tRNA:m(2)G6 methyltransferase Trm14/TrmN from two domains of life
Fislage M, Roovers M, Tuszynska I, Bujnicki JM, Droogmans L, Versées W
Nucleic Acids Res. 2012
RNA-Puzzles: A CASP-like evaluation of RNA three-dimensional structure prediction
Cruz JA, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cao S, Das R, Ding F, Dokholyan NV, Flores SC, Huang L, Lavender CA, Lisi V, Major F, Mikolajczak K, Patel DJ, Philips A, Puton T, Santalucia J, Sijenyi F, Hermann T, Rother K, Rother M, Serganov A, Skorupski M, Soltysinski T, Sripakdeevong P, Tuszynska I, Weeks KM, Waldsich C, Wildauer M, Leontis NB, Westhof E
RNA. 2012
RIBER/DIBER: a software suite for crystal content analysis in the studies of protein-nucleic acid complexes
Chojnowski G, Bujnicki JM, Bochtler M
Bioinformatics. 2012
Highly Pathogenic Alzheimer's Disease Presenilin 1 P117R Mutation Causes a specific Increase in p53 and p21 Protein Levels and Cell Cycle Dysregulation in Human Lymphocytes
Bialopiotrowicz E, Szybinska A, Kuzniewska B, Buizza L, Uberti D, Kuznicki J, Wojda U
J Alzheimers Dis. 2012
Mammalian target of rapamycin complex 1 (MTORC1) and 2 MTORC2) control the dendritic arbor morphology of hippocampal neurons
Urbanska M, Gozdz A, Swiech LJ, Jaworski J
JBC. 2012
APPL1 regulates basal NF-κB activity by stabilizing NIK
Hupalowska A, Pyrzynska B, Miaczynska M
J Cell Sci. 2012
The MIA pathway: A tight bond between protein transport and oxidative folding in mitochondria
Stojanovski D, Bragoszewski P, Chacinska A
BBA-MOL CELL RES. 2012
Related bifunctional restriction endonuclease-methyltransferase triplets: TspDTI, Tth111II/TthHB27I and TsoI with distinct specificities
Zylicz-Stachula A, Zolnierkiewicz O, Lubys A, Ramanauskaite D, Mitkaite G, Bujnicki JM, Skowron P
BMC Mol Biol. 2012
The open reading frame TTC1157 of Thermus thermophilus HB27 encodes the methyltransferase forming N2-methylguanosine at position 6 in tRNA
Roovers M, Oudjama Y, Fislage M, Bujnicki JM, Versées W, Droogmans L
RNA. 2012
Crohn's Disease Risk Alleles on the NOD2 Locus Have Been Maintained by Natural Selection on Standing Variation
Nakagome S, Mano S, Kozlowski L, Bujnicki JM, Shibata H, Fukumaki Y, Kidd JR, Kidd KK, Kawamura S, Oota H
Mol Biol Evol. 2012
Computational methods for prediction of protein-RNA interactions
Puton T, Kozlowski L, Tuszynska I, Rother K, Bujnicki JM
J Struct Biol. 2012
A toolbox for developing bioinformatics software
Rother K, Potrzebowski W, Puton T, Rother M, Wywial E, Bujnicki JM
Brief Bioinform. 2012
Structure and operation of the DNA-translocating type I DNA restriction enzymes
Kennaway CK, Taylor JE, Song CF, Potrzebowski W, Nicholson W, White JH, Swiderska A,Obarska-Kosinska A, Callow P, Cooper LP, Roberts GA, Artero JB,Bujnicki JM, Trinick J, Kneale GG, Dryden DT
Genes Dev. 2012
MetalionRNA: computational predictor of metal-binding sites in RNA structures
Philips A, Milanowska K, Lach G, Boniecki M, Rother K, Bujnicki JM
Bioinformatics. 2012
The mechanics of the cellular division or how to split a sphere into two?
Tinevez JY, Salbreux G, Paluch E
Med Sci (Paris). 2012
Action of Molecular Switches in GPCRs - Theoretical and Experimental Studies
Trzaskowski B, Latek D, Yuan S, Ghoshdastider U, Debinski A, Filipek S
Curr Med Chem. 2012
Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease
Buizza L, Cenini G, Lanni C, Ferrari-Toninelli G, Prandelli C, Govoni S, Buoso E, Racchi M, Barcikowska M, Styczynska M, Szybinska A, Butterfield DA, Memo M, Uberti D
PLoS One. 2012
Mutations in radial spoke head genes and ultrastructural cilia defects in East-European cohort of primary ciliary dyskinesia patients
Ziętkiewicz E, Bukowy-Bieryłło Z, Voelkel K, Klimek B, Dmeńska H, Pogorzelski A, Sulikowska-Rowińska A, Rutkiewicz E, Witt M
PLoS One. 2012
Developmental plasticity of the dendritic compartment: focus on the cytoskeleton
Urbanska M, Swiech L, Jaworski J
Adv Exp Med Biol. 2012
DNA methylation pattern is altered in childhood T-cell acute lymphoblastic leukemia patients as compared with normal thymic subsets: insights into CpG island methylator phenotype in T-ALL
Kraszewska MD, Dawidowska M, Kosmalska M, Sędek L, Grzeszczak W, Szczepański T, Witt M
Leukemia. 2012
T-cell acute lymphoblastic leukaemia: recent molecular biology findings
Kraszewska MD, Dawidowska M, Szczepanski T, Witt M
Br J Haematol. 2012
Immunoglobulin/T-cell receptor gene rearrangements in the diagnostic paradigm of pediatric T-cell acute lymphoblastic leukemia patients
Kraszewska MD, Dawidowska M, Kosmalska M, Sędek L, Grzeszczak W, Szczepański T, Witt M
Leukemia & Lymphoma. 2012
Current genetic methodologies in the identification of disaster victims and in forensic analysis
Ziętkiewicz E, Witt M, Daca P, Zebracka-Gala J, Goniewicz M, Jarząb B, Witt M
J Appl Genet.. 2012
Lack of Pur-alpha alters postnatal brain development and causes megalencephaly
Hokkanen S, Feldmann HM, Ding H, Jung CK, Bojarski L, Renner-Müller I, Schüller U, Kretzschmar H, Wolf E, Herms J
Hum Mol Genet.. 2012
2011
Program badawczy PolSenior – cele i metoda
Błędowski P, Mossakowska M, Szybalska A
Zeszyty Naukowe Ochrony Zdrowia. Zdrowie Publiczne i Zarządzanie. 2011
Virtual screening strategies in drug design - methods and applications
Bielska E, Lucas X, Czerwoniec A, Kasprzak JM, Kaminska KH, Bujnicki JM
BioTechnologia. 2011
Modeling of ligand binding to G protein coupled receptors: cannabinoid CB(1), CB (2) and adrenergic β (2)AR.
Latek D, Kolinski M, Ghoshdastider U, Debinski A, Bombolewski R, Plazinska A, Jozwiak K, Filipek S.
Materials Today. 2011
A high density consensus map of rye (Secale cereale L.) based on DArT markers
Milczarski P, Bolibok-Brągoszewska H, Myśków B, Stojałowski S, Heller-Uszyńska K, Góralska M, Brągoszewski P, Uszyński G, Kilian A, Rakoczy-Trojanowska M
PLoS One. 2011
STAT1 as a novel therapeutical target in pro-atherogenic signal integration of IFNg, TLR4 and IL-6 in vascular disease
Sikorski K, Czerwoniec A, Bujnicki JM, Wesoly J, Bluyssen HAR
Cytokine Growth Factor Rev.. 2011
RNA tertiary structure prediction with ModeRNA
Rother M, Rother K, Puton T, Bujnicki JM
Brief Bioinform. 2011
Databases and bioinformatics tools for the study of DNA repair
Milanowska K, Rother K, Bujnicki JM
Mol Biol Int. 2011
Effect of substrate features and mutagenesis of active site tyrosine residues on the reaction course catalysed by Trypanosoma brucei sterol C-24-methyltransferase
Liu J, Ganapathy K, Wywial E, Bujnicki JM, Nwogwugwu CA, Nes WD
Biochem J. 2011
Identification and modeling of a phosphatase-like domain in a tRNA 2'-O-ribosyl phosphate transferase Rit1p
Czerwoniec A, Bujnicki JM
Cell Cycle. 2011
RNAcentral: A vision for an international database of RNA sequences
Bateman A, Agrawal S, Birney E, Bruford EA, Bujnicki JM, Cochrane G, Cole JR, Dinger ME, Enright AJ, Gardner PP, Gautheret D, Griffiths-Jones S, Harrow J, Herrero J, Holmes IH, Huang HD, Kelly KA, Kersey P, Kozomara A, Lowe TM, Marz M, Moxon S, Pruitt KD, Samuelsson T, Stadler PF, Vilella AJ, Vogel JH, Williams KP, Wright MW, Zwieb C
RNA. 2011
Store-operated calcium entry modulates neuronal network activity in a model of chronic epilepsy
Steinbeck JA, Henke N, Opatz J, Gruszczynska-Biegala J, Schneider L, Theiss S, Hamacher N, Steinfarz B, Golz S, Brüstle O, Kuznicki J, Methner A
Exp Neurol.. 2011
Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex
Schulz C, Lytovchenko O, Melin J, Chacinska A, Guiard B, Neumann P, Ficner R, Jahn O, Schmidt B, Rehling P
J Cell Biol.. 2011
Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis
von der Malsburg K, Müller JM, Bohnert M, Oeljeklaus S, Kwiatkowska P, Becker T, Loniewska-Lwowska A, Wiese S, Rao S, Milenkovic D, Hutu DP, Zerbes RM, Schulze-Specking A, Meyer HE, Martinou JC, Rospert S, Rehling P, Meisinger C, Veenhuis M et all
Dev Cell.. 2011
Importance of single molecular determinants in the fidelity of expanded genetic codes
Antonczak AK, Simova Z, Yonemoto IT, Bochtler M, Piasecka A, Czapinska H, Brancale A, Tippmann EM
Proc Natl Acad Sci U S A.. 2011
The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutières syndrome defects
Figiel M, Chon H, Cerritelli SM, Cybulska M, Crouch RJ, Nowotny M
J Biol Chem. 2011
The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities
Hageman J, van Waarde MA, Zylicz A, Walerych D, Kampinga HH
Biochem J. 2011
ModeRNA: a tool for comparative modeling of RNA 3D structure
Rother M, Rother K, Puton T, Bujnicki JM
Nucleic Acids Res. 2011
Amyloid-associated nucleic acid hybridisation
Braun S, Humphreys C, Fraser E, Brancale A, Bochtler M, Dale TC
PLoS One. 2011
2'-O-ribose methylation of cap2 in human: function and evolution in a horizontally mobile family
Werner M, Purta E, Kaminska KH, Cymerman IA, Campbell DA, Mittra B, Zamudio JR, Sturm NR, Jaworski J, Bujnicki JM
Nucleic Acids Res. 2011
Catalytic mechanism of RNA backbone cleavage by ribonuclease H from quantum mechanics/molecular mechanics simulations
Rosta E, Nowotny M, Yang W, Hummer G
J Am Chem Soc.. 2011
Medical, psychological and socioeconomic aspects of aging in Poland Assumptions and objectives of the PolSenior project
Bledowski P, Mossakowska M, Chudek J, Grodzicki T, Milewicz A, Szybalska A, Wieczorowska-Tobis K, Wiecek A, Bartoszek A, Dabrowski A, Zdrojewski T
Exp Gerontol. 2011
Drug consumption among Polish centenarians
Rajska-Neumann A, Mossakowska M, Klich-Rączka A, Życzkowska J, Grześkowiak E, Shieh S, Wieczorowska-Tobis K
Arch Gerontol Geriatr. 2011
The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins
Becker T, Wenz LS, Krüger V, Lehmann W, Müller JM, Goroncy L, Zufall N, Lithgow T, Guiard B, Chacinska A, Wagner R, Meisinger C, Pfanner N
J Cell Biol.. 2011
DARS-RNP and QUASI-RNP: New statistical potentials for protein-RNA docking
Tuszynska I, Bujnicki JM
BMC Bioinformatics. 2011
Polar actomyosin contractility destabilizes the position of the cytokinetic furrow
Sedzinski J, Biro M, Oswald A, Tinevez JY, Salbreux G, Paluch E
Nature. 2011
Biochemical characterization of APPL endosomes: the role of annexin A2 in APPL membrane recruitment
Urbanska A, Sadowski L, Kalaidzidis Y, Miaczynska M
Traffic. 2011
ModeRNA server: an online tool for modeling RNA 3D structures
Rother M, Milanowska K, Puton T, Jeleniewicz J, Rother K, Bujnicki JM
Bioinformatics. 2011
RNA and protein 3D structure modeling: similarities and differences
Rother K, Rother M, Boniecki M, Puton T, Bujnicki JM
J Mol Model.. 2011
WNT protein-independent constitutive nuclear localization of beta-catenin protein and its low degradation rate in thalamic neurons.
Misztal K, Wisniewska MB, Ambrozkiewicz M, Nagalski A, Kuznicki J
J Biol Chem.. 2011
A single zinc ion is sufficient for an active Trypanosoma brucei tRNA editing deaminase
Spears JL, Rubio MA, Gaston KW, Wywial E, Strikoudis A, Bujnicki JM, Papavasiliou FN, Alfonzo JD
J Biol Chem. 2011
Evidence for an evolutionary antagonism between Mrr and Type III modification systems.
Tesfazgi Mebrhatu M, Wywial E, Ghosh A, Michiels CW, Lindner AB, Taddei F, Bujnicki JM, Van Melderen L, Aertsen A
Nucleic Acids Res. 2011
In vitro culturing of ciliary respiratory cells--a model for studies of genetic diseases
Bukowy Z, Ziętkiewicz E, Witt M
J Appl Genet. 2011
Gene expression studies in cells from primary ciliary dyskinesia patients identify 208 potential ciliary genes
Geremek M, Bruinenberg M, Ziętkiewicz E, Pogorzelski A, Witt M, Wijmenga C
Hum Genet. 2011
NMDA Receptor Activation Suppresses Microtubule Growth and Spine Entry
Kapitein LC, Yau KW, Gouveia SM, van der Zwan WA, Wulf PS, Keijzer N, Demmers J, Jaworski J, Akhmanova A, Hoogenraad CC
J Neurosci. 2011
Mechanics and regulation of cell shape during the cell cycle
Clark AG, Paluch E
Results Probl Cell Differ. 2011
Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neurons
Perycz M, Urbanska AS, Krawczyk PS, Parobczak K, Jaworski J
J Neurosci. 2011
CLIP-170 and IQGAP1 cooperatively regulate dendrite morphology
Swiech L, Blazejczyk M, Urbanska M, Pietruszka P, Dortland BR, Malik AR, Wulf PS, Hoogenraad CC, Jaworski J
J Neurosci. 2011
Distinct molecular regulation of glycogen synthase kinase-3alpha isozyme controlled by its N-terminal region: functional role in calcium/calpain signaling
Azoulay-Alfaguter I, Yaffe Y, Licht-Murava A, Urbanska M, Jaworski J, Pietrokovski S, Hirschberg K, Eldar-Finkelman H
J Biol Chem. 2011
Structure of UvrA nucleotide excision repair protein in complex with modified DNA.
Jaciuk M, Nowak E, Skowronek K, Tańska A, Nowotny M
Nat Struct Mol Biol. 2011
Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment
Pilecka I, Sadowski L, Kalaidzidis Y, Miaczynska M
Exp Cell Res. 2011
Arginine interactions with anatase TiO(2) (100) surface and the perturbation of (49)Ti NMR chemical shifts - a DFT investigation: relevance to Renu-Seeram bio solar cell
Koch R, Lipton AS, Filipek S, Renugopalakrishnan V
J Mol Model. 2011
Differential Roles for STIM1 and STIM2 in Store-Operated Calcium Entry in Rat Neurons
Gruszczynska-Biegala J, Pomorski P, Wisniewska MB, Kuznicki J
PLoS One. 2011
Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth
Sobczak A, Debowska K, Blazejczyk M, Kreutz MR, Kuznicki J, Wojda U
Biochim Biophys Acta. 2011
Cell cycle regulation distinguishes lymphocytes from sporadic and familial Alzheimer's disease patients
Bialopiotrowicz E, Kuzniewska B, Kachamakova-Trojanowska N, Barcikowska M, Kuznicki J, Wojda U
Neurobiol Aging. 2011
DNA intercalation without flipping in the specific ThaI-DNA complex
Firczuk M, Wojciechowski M, Czapinska H, Bochtler M
Nucleic Acids Res. 2011
Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit
Husain N, Obranic S, Koscinski L, Seetharaman J, Babic F, Bujnicki JM, Maravic-Vlahovicek G, Sivaraman J
Nucleic Acids Res. 2011
"4D Biology for health and disease" workshop report
Abrahams JP, Apweiler R, Balling R, Bertero MG, Bujnicki JM, Chayen NE, Chène P, Corthals GL, Dyląg T, Förster F, Heck AJ, Henderson PJ, Herwig R, Jehenson P, Kokalj SJ, Laue E, Legrain P, Martens L, Migliorini C, Musacchio A, Podobnik M, Schertler GF, Sc
N Biotechnol. 2011
Hpy188I-DNA pre- and post-cleavage complexes--snapshots of the GIY-YIG nuclease mediated catalysis
Sokolowska M, Czapinska H, Bochtler M
Nucleic Acids Res. 2011
REPAIRtoire-a database of DNA repair pathways
Milanowska K, Krwawicz J, Papaj G, Kosinski J, Poleszak K, Lesiak J, Osinska E, Rother K, Bujnicki JM
Nucleic Acids Res. 2011
2010
BioCatalogue: a universal catalogue of web services for the life sciences
Bhagat J, Tanoh F, Nzuobontane E, Laurent T, Orlowski J, Roos M, Wolstencroft K, Aleksejevs S, Stevens R, Pettifer S, Lopez R, Goble CA
Nucleic Acids Res. 2010
Trm13p, the tRNA:Xm4 modification enzyme from Saccharomyces cerevisiae is a member of the Rossmann-fold MTase superfamily: prediction of structure and active site
Tkaczuk KL
J Mol Model.. 2010
IGERS: inferring Gibbs energy changes of biochemical reactions from reaction similarities
Rother K, Hoffmann S, Bulik S, Hoppe A, Gasteiger J, Holzhütter HG
Biophys J.. 2010
Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms
Zubrienė A, Gutkowska M, Matulienė J, Chaleckis R, Michailovienė V, Voroncova A, Venclovas C, Zylicz A, Zylicz M, Matulis D
Biophys Chem. 2010
The new platinum(IV) derivative LA-12 shows stronger inhibitory effect on Hsp90 function compared to cisplatin
Kvardova V, Hrstka R, Walerych D, Muller P, Matoulkova E, Hruskova V, Stelclova D, Sova P, Vojtesek B
Mol Cancer. 2010
Mitochondrial genotype and breast cancer predisposition
Czarnecka AM, Krawczyk T, Plak K, Klemba A, Zdrozny M, Arnold RS, Kofler B, Golik P, Szybinska A, Lubinski J, Mossakowska M, Bartnik E, Petros JA
Oncol Rep. 2010
Population specificity of the DNAI1 gene mutation spectrum in primary ciliary dyskinesia (PCD)
Ziętkiewicz E, Nitka B, Voelkel K, Skrzypczak U, Bukowy Z, Rutkiewicz E, Humińska K, Przystałowska H, Pogorzelski A, Witt M
Respir Res. 2010
Decreased expression and the Lys751Gln polymorphism of the XPD gene are associated with extreme longevity
Polosak J, Roszkowska-Gancarz M, Kurylowicz A, Owczarz M, Dobosz P, Mossakowska M, Szybinska A, Puzianowska-Kuznicka M
Biogerontology. 2010
An age-related decrease in factor V Leiden frequency among Polish subjects
Adler G, Parczewski M, Czerska E, Loniewska B, Kaczmarczyk M, Gumprecht J, Grzeszczak W, Szybinska A, Mossakowska M, Ciechanowicz A
J Appl Genet. 2010
Mitochondrial genotype in vulvar carcinoma - cuckoo in the nest
Klemba A, Kowalewska M, Kukwa W, Tonska K, Szybinska A, Mossakowska M, Scinska A, Golik P, Koper K, Radziszewski J, Kukwa A, Czarnecka AM, Bartnik E
J Biomed Sci. 2010
The dissection of transcriptional modules regulated by various drugs of abuse in the mouse striatum.
Piechota M, Korostynski M, Solecki W, Gieryk A, Slezak M, Bilecki W, Ziolkowska B, Kostrzewa E, Cymerman I, Swiech L, Jaworski J, Przewlocki R
Genome Biol. 2010
Morgana/CHP-1 is a novel chaperone able to protect cells from stress.
Michowski W, Ferretti R, Wisniewska MB, Ambrozkiewicz M, Beresewicz M, Fusella F, Skibinska-Kijek A, Zablocka B, Brancaccio M, Tarone G, Kuznicki J.
Biochim Biophys Acta. 2010
LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain.
Wisniewska MB, Misztal K, Michowski W, Szczot M, Purta E, Lesniak W, Klejman ME, Dabrowski M, Filipkowski RK, Nagalski A, Mozrzymas JW, Kuznicki J.
J Neurosci. 2010
Alu-repeat-induced deletions within the NCF2 gene causing p67-phox-deficient chronic granulomatous disease (CGD)
Gentsch M, Kaczmarczyk A, van Leeuwen K, de Boer M, Kaus-Drobek M, Dagher MC, Kaiser P, Arkwright PD, Gahr M, Rösen-Wolff A, Bochtler M, Secord E, Britto-Williams P, Saifi GM, Maddalena A, Dbaibo G, Bustamante J, Casanova JL, Roos D, Roesler J
Hum Mutat. 2010
1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state
Chojnowski G, Breer K, Narczyk M, Wielgus-Kutrowska B, Czapinska H, Hashimoto M, Hikishima S, Yokomatsu T, Bochtler M, Girstun A, Staroń K, Bzowska A
Biochem Biophys Res Commun. 2010
Control of directed cell migration in vivo by membrane-to-cortex attachment.
Diz-Muñoz A, Krieg M, Bergert M, Ibarlucea-Benitez I, Muller DJ, Paluch E, Heisenberg CP
PLoS Biol. 2010
A putative mobile genetic element carrying a novel type IIF restriction-modification system (PluTI).
Khan F, Furuta Y, Kawai M, Kaminska KH, Ishikawa K, Bujnicki JM, Kobayashi I
Nucleic Acids Res. 2010
Predicting atomic details of the unfolding pathway for YibK, a knotted protein from the SPOUT superfamily
Tuszynska I, Bujnicki JM
J Biomol Struct Dyn. 2010
Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria.
Kaminska KH, Purta E, Hansen LH, Bujnicki JM, Vester B, Long KS
Nucleic Acids Res. 2010
The crystal structure of Escherichia coli spermidine synthase SpeE reveals a unique substrate-binding pocket.
Zhou X, Chua TK, Tkaczuk KL, Bujnicki JM, Sivaraman J
J Struct Biol. 2010
Physiological truncation and domain organization of a novel uracil-DNA-degrading factor.
Pukáncsik M, Békési A, Klement E, Hunyadi-Gulyás E, Medzihradszky KF, Kosinski J, Bujnicki JM, Alfonso C, Rivas G, Vértessy BG
FEBS J. 2010
The YTH domain is a novel RNA binding domain.
Zhang Z, Theler D, Kaminska KH, Hiller M, de la Grange P, Pudimat R, Rafalska I, Heinrich B, Bujnicki JM, Allain FH, Stamm S
J Biol Chem. 2010
Co-evolution-driven switch of J-protein specificity towards an Hsp70 partner.
Pukszta S, Schilke B, Dutkiewicz R, Kominek J, Moczulska K, Stepien B, Reitenga KG, Bujnicki JM, Williams B, Craig EA, Marszalek J
EMBO Rep. 2010
New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA.
Kempenaers M, Roovers M, Oudjama Y, Tkaczuk KL, Bujnicki JM, Droogmans L
Nucleic Acids Res. 2010
Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.
Husain N, Tkaczuk KL, Tulsidas SR, Kaminska KH, Cubrilo S, Maravić-Vlahovicek G, Bujnicki JM, Sivaraman J
Nucleic Acids Res. 2010
Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair.
Kosinski J, Hinrichsen I, Bujnicki JM, Friedhoff P, Plotz G
Hum Mutat. 2010
Crystal structure of a fructokinase homolog from Halothermothrix orenii
Chua TK, Seetharaman J, Kasprzak JM, Ng C, Patel BK, Love C, Bujnicki JM, Sivaraman J
J Struct Biol. 2010
FILTREST3D: discrimination of structural models using restraints from experimental data.
Gajda MJ, Tuszynska I, Kaczor M, Bakulina AY, Bujnicki JM
Bioinformatics. 2010
Production and characterization of recombinant protein preparations of Endonuclease G-homologs from yeast, C. elegans and humans.
Kieper J, Lauber C, Gimadutdinow O, Urbańska A, Cymerman I, Ghosh M, Szczesny B, Meiss G
Protein Expr Purif. 2010
Expression of Ttyh1, a member of the Tweety family in neurons in vitro and in vivo and its potential role in brain pathology.
Stefaniuk M, Swiech L, Dzwonek J, Lukasiuk K
J Neurochem. 2010
Crystal structures of RNase H2 in complex with nucleic acid reveal the mechanism of RNA-DNA junction recognition and cleavage.
Rychlik MP, Chon H, Cerritelli SM, Klimek P, Crouch RJ, Nowotny M
Mol Cell. 2010
Study of a structurally similar kappa opioid receptor agonist and antagonist pair by molecular dynamics simulations.
Kolinski M, Filipek S
J Mol Model. 2010
Fizjologia i molekularny mechanizm działania glikokortykoidów.
Nagalski A, Kiersztan A.
Postepy Hig Med Dosw. 2010
Resistance of the dopamine D4 receptor to agonist-induced internalization and degradation.
Spooren A, Rondou P, Debowska K, Lintermans B, Vermeulen L, Samyn B, Skieterska K, Debyser G, Devreese B, Vanhoenacker P, Wojda U, Haegeman G, Van Craenenbroeck K.
Cell Signal. 2010
Increased CD44 gene expression in lymphocytes derived from Alzheimer disease patients.
Uberti D, Cenini G, Bonini SA, Barcikowska M, Styczynska M, Szybinska A, Memo M.
Neurodegener Dis. 2010
In vitro findings of alterations in intracellular calcium homeostasis in schizophrenia.
Bojarski L, Debowska K, Wojda U.
Prog Neuropsychopharmacol Biol Psychiatry. 2010
Crystallization of the Photosystem II core complex and its chlorophyll binding subunit CP43 from transplastomic plants of Nicotiana tabacum
Piano D, El Alaoui S, Korza HJ, Filipek R, Sabala I, Haniewicz P, Buechel C, De Sanctis D, Bochtler M
Photosynth Res. 2010
Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.
Kirkegaard T, Roth AG, Petersen NH, Mahalka AK, Olsen OD, Moilanen I, Zylicz A, Knudsen J, Sandhoff K, Arenz C, Kinnunen PK, Nylandsted J, Jäättelä M
Nature. 2010
Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo.
Zurawska A, Urbanski J, Matuliene J, Baraniak J, Klejman MP, Filipek S, Matulis D, Bieganowski P
Biochim Biophys Acta. 2010
ATP binding to Hsp90 is sufficient for effective chaperoning of p53 protein.
Walerych D, Gutkowska M, Klejman MP, Wawrzynow B, Tracz Z, Wiech M, Zylicz M, Zylicz A
J Biol Chem. 2010
2009
Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.
Ohya T, Miaczynska M, Coskun U, Lommer B, Runge A, Drechsel D, Kalaidzidis Y, Zerial M
Nature. 2009
[Effectors of GTPase Rab5 in endocytosis and signal transduction]
Olchowik M, Miaczyńska M
Postepy Biochem. 2009
Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex
Banach-Orlowska M, Pilecka I, Torun A, Pyrzynska B, Miaczynska M
Biochem J. 2009
Signaling from endosomes: location makes a difference.
Sadowski L, Pilecka I, Miaczynska M
Exp Cell Res. 2009
Studies of the Activation Steps Concurrent to Ligand Binding in δOR and κOR Opioid Receptors Based on Molecular Dynamics Simulations
M. Kolinfski, S. Filipek
TOSBJ. 2009
CacyBP/SIP binds ERK1/2 and affects transcriptional activity of Elk-1
Kilanczyk E, Filipek S, Jastrzebska B, Filipek A
Biochem Biophys Res Commun. 2009
Generation and characterization of a novel, permanently active S100P mutant.
Austermann J, Nazmi AR, Heil A, Fritz G, Kolinski M, Filipek S, Gerke V
Biochim Biophys Acta. 2009
Study on the feasibility of bacteriorhodopsin as bio-photosensitizer in excitonic solar cell: a first report.
Thavasi V, Lazarova T, Filipek S, Kolinski M, Querol E, Kumar A, Ramakrishna S, Padrós E, Renugopalakrishnan V
J Nanosci Nanotechnol. 2009
Bio-batteries and bio-fuel cells: leveraging on electronic charge transfer proteins.
Kannan AM, Renugopalakrishnan V, Filipek S, Li P, Audette GF, Munukutla L
J Nanosci Nanotechnol. 2009
“Nanomaterials for Energy Convertion Applications”
V. Renugopalakrishnan, A. M. Kannan, S. Srinivasan, V. Thavasi, S. Ramakrishna, P. Li, A. Mershin, S. Filipek, A. Kumar, J. Dutta, A. Jaya, L. Munukutla, S. Velumani, G. F. Audette
\"Nanomaterials for Energy Storage Applications\". 2009
Expression of STIM1 in brain and puncta-like co-localization of STIM1 and ORAI1 upon depletion of Ca(2+) store in neurons.
Klejman ME, Gruszczynska-Biegala J, Skibinska-Kijek A, Wisniewska MB, Misztal K, Blazejczyk M, Bojarski L, Kuznicki J.
Neurochem Int. 2009
Immunolocalization of STIM1 in the mouse brain.
Skibinska-Kijek A, Wisniewska MB, Gruszczynska-Biegala J, Methner A, Kuznicki J
Acta Neurobiol Exp (Wars). 2009
Presenilin-dependent expression of STIM proteins and dysregulation of capacitative Ca2+ entry in familial Alzheimer's disease.
Bojarski L, Pomorski P, Szybinska A, Drab M, Skibinska-Kijek A, Gruszczynska-Biegala J, Kuznicki J
Biochim Biophys Acta. 2009
Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA
Sokolowska M, Czapinska H, Bochtler M
Nucleic Acids Res. 2009
Modeling of Escherichia coli Endonuclease V structure in complex with DNA.
Majorek KA, Bujnicki JM
J Mol Model. 2009
The mitotic kinesin-14 Ncd drives directional microtubule-microtubule sliding.
Fink G, Hajdo L, Skowronek KJ, Reuther C, Kasprzak AA, Diez S
Nat Cell Biol. 2009
MODOMICS: a database of RNA modification pathways. 2008 update
Czerwoniec A, Dunin-Horkawicz S, Purta E, Kaminska KH, Kasprzak JM, Bujnicki JM, Grosjean H, Rother K
Nucleic Acids Res. 2009
Functional analysis of MmeI from methanol utilizer Methylophilus methylotrophus, a subtype IIC restriction-modification enzyme related to type I enzymes.
Nakonieczna J, Kaczorowski T, Obarska-Kosinska A, Bujnicki JM
Appl Environ Microbiol. 2009
The structure of M.EcoKI Type I DNA methyltransferase with a DNA mimic antirestriction protein
Kennaway CK, Obarska-Kosinska A, White JH, Tuszynska I, Cooper LP, Bujnicki JM, Trinick J, Dryden DT
Nucleic Acids Res. 2009
Conformation of a plasmid replication initiator protein affects its proteolysis by ClpXP system
Pierechod M, Nowak A, Saari A, Purta E, Bujnicki JM, Konieczny I
Protein Sci. 2009
Medaka: a promising model animal for comparative population genomics.
Matsumoto Y, Oota H, Asaoka Y, Nishina H, Watanabe K, Bujnicki JM, Oda S, Kawamura S, Mitani H
BMC Res Notes. 2009
Fast Structural Alignment of Biomolecules Using a Hash Table, N-Grams and String Descriptors
Bauer RA, Rother K, Moor P, Reinert K, Steinke T, Bujnicki JM
Algorithms. 2009
YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA.
Purta E, O'Connor M, Bujnicki JM, Douthwaite S
Mol Microbiol. 2009
AAN82231 protein from uropathogenic E. coli CFT073 is a close paralog of DsbB enzymes and does not belong to the DsbI family
Pawłowski M, Lasica AM, Jagusztyn-Krynicka EK, Bujnicki JM
Pol J Microbiol. 2009
Cloning and analysis of a bifunctional methyltransferase/restriction endonuclease TspGWI, the prototype of a Thermus sp. enzyme family.
Zylicz-Stachula A, Bujnicki JM, Skowron PM
BMC Mol Biol. 2009
SMN-assisted assembly of snRNP-specific Sm cores in trypanosomes.
Palfi Z, Jaé N, Preusser C, Kaminska KH, Bujnicki JM, Lee JH, Günzl A, Kambach C, Urlaub H, Bindereif A
Genes Dev. 2009
Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase.
Pena V, Jovin SM, Fabrizio P, Orlowski J, Bujnicki JM, Lührmann R, Wahl MC
Mol Cell. 2009
Integrating ELF4 into the circadian system through combined structural and functional studies.
Kolmos E, Nowak M, Werner M, Fischer K, Schwarz G, Mathews S, Schoof H, Nagy F, Bujnicki JM, Davis SJ
HFSP J. 2009
Identification and classification of bcl genes and proteins of Bacillus cereus group organisms and their application in Bacillus anthracis detection and fingerprinting.
Leski TA, Caswell CC, Pawlowski M, Klinke DJ, Bujnicki JM, Hart SJ, Lukomski S
Appl Environ Microbiol. 2009
Mathematical modelling of the influence of heat shock proteins on cancer invasion of tissue.
Szymańska Z, Urbański J, Marciniak-Czochra A.
J Math Biol. 2009
Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions.
Walerych D, Olszewski MB, Gutkowska M, Helwak A, Zylicz M, Zylicz A
Oncogene. 2009
Cooperative regulation of the interferon regulatory factor-1 tumor suppressor protein by core components of the molecular chaperone machinery
Narayan V, Eckert M, Zylicz A, Zylicz M, Ball KL
J Biol Chem. 2009
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity.
Jaworski J, Kapitein LC, Gouveia SM, Dortland BR, Wulf PS, Grigoriev I, Camera P, Spangler SA, Di Stefano P, Demmers J, Krugers H, Defilippi P, Akhmanova A, Hoogenraad CC
Neuron. 2009
Biochemical characterization and expression analysis of a novel EF-hand Ca2+ binding protein calmyrin2 (Cib2) in brain indicates its function in NMDA receptor mediated Ca2+ signaling.
Blazejczyk M, Sobczak A, Debowska K, Wisniewska MB, Kirilenko A, Pikula S, Jaworski J, Kuznicki J, Wojda U.
Arch Biochem Biophys. 2009
Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription.
Rashid S, Pilecka I, Torun A, Olchowik M, Bielinska B, Miaczynska M
J Biol Chem. 2009
Endocytic proteins in the regulation of nuclear signaling, transcription and tumorigenesis
Pyrzynska B, Pilecka I, Miaczynska M
Mol Oncol. 2009
Modulation of molecular interactions and function by rhodopsin palmitylation
Park PS, Sapra KT, Jastrzebska B, Maeda T, Maeda A, Pulawski W, Kono M, Lem J, Crouch RK, Filipek S, Müller DJ, Palczewski K
Biochemistry. 2009
Properties of Radical Anions of Triptindanones and Indanones: Electronic Communication and Stability of Ion Pairs Containing Lithium Cations
J.S. Jaworski, A. Kosson, S. Filipek, M. Kolinski, D. Kuck
J. Phys. Chem. C. 2009
A function for the RING finger domain in the allosteric control of MDM2 conformation and activity.
Wawrzynow B, Pettersson S, Zylicz A, Bramham J, Worrall E, Hupp TR, Ball KL
J Biol Chem. 2009
2008
Sequence analysis of 21 genes located in the Kartagener syndrome linkage region on chromosome 15q
Geremek M, Schoenmaker F, Zietkiewicz E, Pogorzelski A, Diehl S, Wijmenga C, Witt M
Eur J Hum Genet. 2008
Implementation of the standard strategy for identification of Ig/TCR targets for minimal residual disease diagnostics in B-cell precursor ALL pediatric patients: Polish experience
Dawidowska M, Jółkowska J, Szczepański T, Derwich K, Wachowiak J, Witt M
Arch Immunol Ther Exp (Warsz). 2008
Organelle-specific zinc detection using zinpyr-labeled fusion proteins in live cells
Tomat E, Nolan EM, Jaworski J, Lippard SJ
J Am Chem Soc. 2008
Yin Yang 1 is a critical repressor of matrix metalloproteinase-9 expression in brain neurons
Rylski M, Amborska R, Zybura K, Mioduszewska B, Michaluk P, Jaworski J, Kaczmarek L
J Biol Chem. 2008
Microtubule plus-end tracking proteins in differentiated mammalian cells.
Jaworski J, Hoogenraad CC, Akhmanova A
Int J Biochem Cell Biol. 2008
Role of mTOR in physiology and pathology of the nervous system
Swiech L, Perycz M, Malik A, Jaworski J
Biochim Biophys Acta. 2008
Injury induced dendritic plasticity in the mature central nervous system.
Macias M
Acta Neurobiol Exp (Wars). 2008
Molecular basis of dendritic arborization
Urbanska M, Blazejczyk M, Jaworski J
Acta Neurobiol Exp (Wars). 2008
Inducible cAMP early repressor (ICER)-evoked delayed neuronal death in the organotypic hippocampal culture
Mioduszewska B, Jaworski J, Szklarczyk AW, Klejman A, Kaczmarek L
J Neurosci Res. 2008
On the transition from the meiotic to mitotic cell cycle during early mouse development.
Kubiak JZ, Ciemerych MA, Hupalowska A, Sikora-Polaczek M, Polanski Z
Int J Dev Biol. 2008
Molecular dynamics of mu opioid receptor complexes with agonists and antagonists
Kolinski M, Filipek S.
The Open Struct. Biol. J.. 2008
Molecular models of the interface between anterior pharynx-defective protein 1 (APH-1) and presenilin involving GxxxG motifs
Jozwiak K, Krzysko KA, Bojarski L, Gacia M, Filipek S
ChemMedChem. 2008
Determination and modelling of stereoselective interactions of ligands with drug transporters: a key dimension in the understanding of drug disposition
Bhatia P, Kolinski M, Moaddel R, Jozwiak K, Wainer IW
Xenobiotica. 2008
Ca2+ -dependent regulation of phototransduction.
Stephen R, Filipek S, Palczewski K, Sousa MC
Photochem Photobiol. 2008
Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy.
Majewski T, Lee S, Jeong J, Yoon DS, Kram A, Kim MS, Tuziak T, Bondaruk J, Lee S, Park WS, Tang KS, Chung W, Shen L, Ahmed SS, Johnston DA, Grossman HB, Dinney CP, Zhou JH, Harris RA, Snyder C, Filipek S, Narod SA, Watson P, Lynch HT, Gazdar A, Bar-Eli M,
Lab Invest. 2008
Variation in NPC1, the gene encoding Niemann-Pick C1, a protein involved in intracellular cholesterol transport, is associated with Alzheimer disease and/or aging in the Polish population
Erickson RP, Larson-Thomé K, Weberg L, Szybinska A, Mossakowska M, Styczynska M, Barcikowska M, Kuznicki J
Neurosci Lett. 2008
Statins impair antitumor effects of rituximab by inducing conformational changes of CD20.
Winiarska M, Bil J, Wilczek E, Wilczynski GM, Lekka M, Engelberts PJ, Mackus WJ, Gorska E, Bojarski L, Stoklosa T, Nowis D, Kurzaj Z, Makowski M, Glodkowska E, Issat T, Mrowka P, Lasek W, Dabrowska-Iwanicka A, Basak GW, Wasik M, Warzocha K, Sinski M, Gaciong Z, Jakobisiak M, Parren PW, Golab J.
PLoS Med. 2008
Polish Centenarians Programme. Multidisciplinary studies of successful ageing: aims, methods, and preliminary results
Mossakowska M, Barcikowska M, Broczek K, Grodzicki T, Klich-Raczka A, Kupisz-Urbanska M, Podsiadly-Marczykowska T, Sikora E, Szybinska A, Wieczorowska-Tobis K, Zyczkowska J, Kuznicki J
Exp Gerontol. 2008
Conformationally altered p53: a novel Alzheimer's disease marker?
Lanni C, Racchi M, Mazzini G, Ranzenigo A, Polotti R, Sinforiani E, Olivari L, Barcikowska M, Styczynska M, Kuznicki J, Szybinska A, Govoni S, Memo M, Uberti D
Mol Psychiatry. 2008
Sgt1 has co-chaperone properties and is up-regulated by heat shock.
Zabka M, Leśniak W, Prus W, Kuźnicki J, Filipek A
Biochem Biophys Res Commun. 2008
Involvement of S100A6 (calcyclin) and its binding partners in intracellular signaling pathways
Filipek A, Michowski W, Kuznicki J
Adv Enzyme Regul. 2008
Central base pair flipping and discrimination by PspGI
Szczepanowski RH, Carpenter MA, Czapinska H, Zaremba M, Tamulaitis G, Siksnys V, Bhagwat AS, Bochtler M
Nucleic Acids Res. 2008
How PspGI, catalytic domain of EcoRII and Ecl18kI acquire specificities for different DNA targets
Tamulaitis G, Zaremba M, Szczepanowski RH, Bochtler M, Siksnys V
Nucleic Acids Res. 2008
Thermodynamic studies of interactions of calf spleen PNP with acyclic phosphonate inhibitors
Breer K, Wielgus-Kutrowska B, Hashimoto M, Hikishima S, Yokomatsu T, Szczepanowski RH, Bochtler M, Girstun A, Starón K, Bzowska A
Nucleic Acids Symp Ser (Oxf). 2008
The recognition domain of the BpuJI restriction endonuclease in complex with cognate DNA at 1.3-A resolution
Sukackaite R, Grazulis S, Bochtler M, Siksnys V.
J Mol Biol. 2008
Crystal structure and mechanism of the Staphylococcus cohnii virginiamycin B lyase (Vgb)
Lipka M, Filipek R, Bochtler M
Biochemistry. 2008
Modeling and experimental analyses reveal a two-domain structure and amino acids important for the activity of aminoglycoside resistance methyltransferase Sgm.
Maravić Vlahovicek G, Cubrilo S, Tkaczuk KL, Bujnicki JM
Biochim Biophys Acta. 2008
Structural integrity of the beta beta alpha-Metal finger motif is required for DNA binding and stable protein-DNA complex formation in R.KpnI.
Vasu K, Saravanan M, Bujnicki JM, Nagaraja V
Biochim Biophys Acta. 2008
Structural bioinformatics analysis of enzymes involved in the biosynthesis pathway of the hypermodified nucleoside ms(2)io(6)A37 in tRNA.
Kaminska KH, Baraniak U, Boniecki M, Nowaczyk K, Czerwoniec A, Bujnicki JM
Proteins. 2008
Sequence-structure-function analysis of the bifunctional enzyme MnmC that catalyses the last two steps in the biosynthesis of hypermodified nucleoside mnm5s2U in tRNA.
Roovers M, Oudjama Y, Kaminska KH, Purta E, Caillet J, Droogmans L, Bujnicki JM
Proteins. 2008
Bacteriophage Mu Mom protein responsible for DNA modification is a new member of the acyltransferase superfamily.
Kaminska KH, Bujnicki JM
Cell Cycle. 2008
The TbMTr1 spliced leader RNA cap 1 2'-O-ribose methyltransferase from Trypanosoma brucei acts with substrate specificity
Mittra B, Zamudio JR, Bujnicki JM, Stepinski J, Darzynkiewicz E, Campbell DA, Sturm NR
J Biol Chem. 2008
Virtual screening and experimental verification to identify potential inhibitors of the ErmC methyltransferase responsible for bacterial resistance against macrolide antibiotics.
Feder M, Purta E, Koscinski L, Cubrilo S, Maravic Vlahovicek G, Bujnicki JM
ChemMedChem. 2008
EXOG, a novel paralog of Endonuclease G in higher eukaryotes.
Cymerman IA, Chung I, Beckmann BM, Bujnicki JM, Meiss G
Nucleic Acids Res. 2008
Predicting the complex structure and functional motions of the outer membrane transporter and signal transducer FecA.
Sen TZ, Kloster M, Jernigan RL, Kolinski A, Bujnicki JM, Kloczkowski A
Biophys J. 2008
The structure of sucrose phosphate synthase from Halothermothrix orenii reveals its mechanism of action and binding mode.
Chua TK, Bujnicki JM, Tan TC, Huynh F, Patel BK, Sivaraman J
Plant Cell. 2008
The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK).
Roovers M, Kaminska KH, Tkaczuk KL, Gigot D, Droogmans L, Bujnicki JM
Nucleic Acids Res. 2008
Structural and evolutionary classification of Type II restriction enzymes based on theoretical and experimental analyses.
Orlowski J, Bujnicki JM
Nucleic Acids Res. 2008
Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits.
White J, Li Z, Sardana R, Bujnicki JM, Marcotte EM, Johnson AW
Mol Cell Biol. 2008
The PMS2 subunit of human MutLalpha contains a metal ion binding domain of the iron-dependent repressor protein family.
Kosinski J, Plotz G, Guarné A, Bujnicki JM, Friedhoff P
J Mol Biol. 2008
YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.
Purta E, Kaminska KH, Kasprzak JM, Bujnicki JM, Douthwaite S
RNA. 2008
MetaMQAP: a meta-server for the quality assessment of protein models.
Pawlowski M, Gajda MJ, Matlak R, Bujnicki JM
BMC Bioinformatics. 2008
Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes.
Sunita S, Tkaczuk KL, Purta E, Kasprzak JM, Douthwaite S, Bujnicki JM, Sivaraman J
J Mol Biol. 2008
HsdR subunit of the type I restriction-modification enzyme EcoR124I: biophysical characterisation and structural modelling.
Obarska-Kosinska A, Taylor JE, Callow P, Orlowski J, Bujnicki JM, Kneale GG
J Mol Biol. 2008
YccW is the m5C methyltransferase specific for 23S rRNA nucleotide 1962
Purta E, O\'Connor M, Bujnicki JM, Douthwaite S
J Mol Biol. 2008
IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis.
Gyrd-Hansen M, Darding M, Miasari M, Santoro MM, Zender L, Xue W, Tenev T, da Fonseca PC, Zvelebil M, Bujnicki JM, Lowe S, Silke J, Meier P
Nat Cell Biol. 2008
Mutational analysis and a structural model of methyl-directed restriction enzyme Mrr.
Orlowski J, Mebrhatu MT, Michiels CW, Bujnicki JM, Aertsen A
Biochem Biophys Res Commun. 2008
Fhit proteins can also recognize substrates other than dinucleoside polyphosphates.
Guranowski A, Wojdyła AM, Pietrowska-Borek M, Bieganowski P, Khurs EN, Cliff MJ, Blackburn GM, Błaziak D, Stec WJ
FEBS Lett. 2008
The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1.
Sbroggiò M, Ferretti R, Percivalle E, Gutkowska M, Zylicz A, Michowski W, Kuznicki J, Accornero F, Pacchioni B, Lanfranchi G, Hamm J, Turco E, Silengo L, Tarone G, Brancaccio M.
FEBS Lett. 2008
ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1.
Stevens C, Pettersson S, Wawrzynow B, Wallace M, Ball K, Zylicz A, Hupp TR
FEBS J. 2008
Hsp90n - An accidental product of a fortuitous chromosomal translocation rather than a regular Hsp90 family member of human proteome
Zurawska A, Urbanski J, Bieganowski P
Biochim Biophys Acta. 2008
2007
The nutritional habits among centenarians living in Warsaw
Kołłajtis-Dołowy A, Pietruszka B, Kałuza J, Pawlińiska-Chmara R, Broczek K, Mossakowska M
Rocz Panstw Zakl Hig. 2007
Evaluation of neuroendocrine status in longevity
Baranowska B, Wolinska-Witort E, Bik W, Baranowska-Bik A, Martynska L, Broczek K, Mossakowska M, Chmielowska M
Neurobiol Aging. 2007
Effects of age and gender on micronucleus and chromosome nondisjunction frequencies in centenarians and younger subjects
Wojda A, Zietkiewicz E, Witt M
Mutagenesis. 2007
Beta-dystroglycan as a target for MMP-9, in response to enhanced neuronal activity.
Michaluk P, Kolodziej L, Mioduszewska B, Wilczynski GM, Dzwonek J, Jaworski J, Gorecki DC, Ottersen OP, Kaczmarek L
J Biol Chem. 2007
TIMP-1 abolishes MMP-9-dependent long-lasting long-term potentiation in the prefrontal cortex.
Okulski P, Jay TM, Jaworski J, Duniec K, Dzwonek J, Konopacki FA, Wilczynski GM, Sánchez-Capelo A, Mallet J, Kaczmarek L
Biol Psychiatry. 2007
Nuclear functions of endocytic proteins
Pilecka I, Banach-Orlowska M, Miaczynska M
Eur J Cell Biol. 2007
Early-onset Alzheimer's disease with a de novo mutation in the presenilin 1 gene
Golan MP, Styczyńska M, Jóźwiak K, Walecki J, Maruszak A, Pniewski J, Lugiewicz R, Filipek S, Zekanowski C, Barcikowska M
Exp Neurol. 2007
Molecular modelling of the complex of oligomeric rhodopsin and its G protein.
Krzysko KA, Kolinski M, Filipek S.
J Phys Condens Matter. 2007
Forerunner genes contiguous to RB1 contribute to the development of in situ neoplasia.
Lee S, Jeong J, Majewski T, Scherer SE, Kim MS, Tuziak T, Tang KS, Baggerly K, Grossman HB, Zhou JH, Shen L, Bondaruk J, Ahmed SS, Samanta S, Spiess P, Wu X, Filipek S, McConkey D, Bar-Eli M, Issa JP, Benedict WF, Czerniak B
Proc Natl Acad Sci U S A. 2007
Stabilizing effect of Zn2+ in native bovine rhodopsin
Park PS, Sapra KT, Koliński M, Filipek S, Palczewski K, Muller DJ
J Biol Chem. 2007
Biochemical properties of endogenous presenilin 1 and presenilin 2 in cultured human B-lymphocytes
Bojarski L, Lewandowicz A, Blazejczyk M, Sobczak A, Kuznicki J, Wojda U
Clin Chem Lab Med. 2007
Epigenetic control of the S100A6 (calcyclin) gene expression
Leśniak W, Słomnicki ŁP, Kuźnicki J
J Invest Dermatol. 2007
CacyBP/SIP interacts with tubulin in neuroblastoma NB2a cells and induces formation of globular tubulin assemblies
Schneider G, Nieznanski K, Kilanczyk E, Bieganowski P, Kuznicki J, Filipek A
Biochim Biophys Acta. 2007
Hsp70 is a new target of Sgt1-an interaction modulated by S100A6.
Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J,Filipek A.
Biochem Biophys Res Commun. 2007
Association study of cholesterol-related genes in Alzheimer's disease
Wollmer MA, Sleegers K, Ingelsson M, Zekanowski C, Brouwers N, Maruszak A, Brunner F, Huynh KD, Kilander L, Brundin RM, Hedlund M, Giedraitis V, Glaser A, Engelborghs S, De Deyn PP, Kapaki E, Tsolaki M, Daniilidou M, Molyva D, Paraskevas GP, Thal DR, Barcikowska M, Kuznicki J, Lannfelt L, Van Broeckhoven C, Nitsch RM, Hock C, Papassotiropoulos A.
Neurogenetics. 2007
The highest reflection intensity in a resolution shell
Bochtler M, Chojnowski G
Acta Crystallogr A. 2007
Mutational analysis of peptidoglycan amidase MepA
Firczuk M, Bochtler M.
Biochemistry. 2007
Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically
Kaus-Drobek M, Czapinska H, Sokołowska M, Tamulaitis G, Szczepanowski RH, Urbanke C, Siksnys V, Bochtler M
Nucleic Acids Res. 2007
Restriction endonucleases that resemble a component of the bacterial DNA repair machinery
Sokolowska M, Kaus-Drobek M, Czapinska H, Tamulaitis G, Siksnys V, Bochtler M
Cell Mol Life Sci. 2007
Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA.
Sokolowska M, Kaus-Drobek M, Czapinska H, Tamulaitis G, Szczepanowski RH, Urbanke C, Siksnys V, Bochtler M
J Mol Biol. 2007
Nucleotide flipping by restriction enzymes analyzed by 2-aminopurine steady-state fluorescence
Tamulaitis G, Zaremba M, Szczepanowski RH, Bochtler M, Siksnys V
Nucleic Acids Res. 2007
The 2'-O-ribose methyltransferase for cap 1 of spliced leader RNA and U1 small nuclear RNA in Trypanosoma brucei
Zamudio JR, Mittra B, Foldynová-Trantírková S, Zeiner GM, Lukes J, Bujnicki JM, Sturm NR, Campbell DA
Mol Cell Biol. 2007
Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.
Tkaczuk KL, Dunin-Horkawicz S, Purta E, Bujnicki JM
BMC Bioinformatics. 2007
Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC.
Sunita S, Purta E, Durawa M, Tkaczuk KL, Swaathi J, Bujnicki JM, Sivaraman J
Nucleic Acids Res. 2007
Human lysosomal DNase IIalpha contains two requisite PLD-signature (HxK) motifs: evidence for a pseudodimeric structure of the active enzyme species.
Schäfer P, Cymerman IA, Bujnicki JM, Meiss G
Protein Sci. 2007
SURF'S UP! - protein classification by surface comparisons
Sasin JM, Godzik A, Bujnicki JM
J Biosci. 2007
Transcriptome profile of human colorectal adenomas.
Sabates-Bellver J, Van der Flier LG, de Palo M, Cattaneo E, Maake C, Rehrauer H, Laczko E, Kurowski MA, Bujnicki JM, Menigatti M, Luz J, Ranalli TV, Gomes V, Pastorelli A, Faggiani R, Anti M, Jiricny J, Clevers H, Marra G
Mol Cancer Res. 2007
PROTMAP2D: visualization, comparison and analysis of 2D maps of protein structure.
Pietal MJ, Tuszynska I, Bujnicki JM
Bioinformatics. 2007
Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa.
Pena V, Liu S, Bujnicki JM, Lührmann R, Wahl MC
Mol Cell. 2007
Conserved amino acids in each subunit of the heteroligomeric tRNA m1A58 Mtase from Saccharomyces cerevisiae contribute to tRNA binding.
Ozanick SG, Bujnicki JM, Sem DS, Anderson JT
Nucleic Acids Res. 2007
I-Ssp6803I: the first homing endonuclease from the PD-(D/E)XK superfamily exhibits an unusual mode of DNA recognition
Orlowski J, Boniecki M, Bujnicki JM
Bioinformatics. 2007
Novel protein fold discovered in the PabI family of restriction enzymes.
Miyazono K, Watanabe M, Kosinski J, Ishikawa K, Kamo M, Sawasaki T, Nagata K, Bujnicki JM, Endo Y, Tanokura M, Kobayashi I
Nucleic Acids Res. 2007
Structure and evolutionary origin of Ca(2+)-dependent herring type II antifreeze protein.
Liu Y, Li Z, Lin Q, Kosinski J, Seetharaman J, Bujnicki JM, Sivaraman J, Hew CL
PLoS One. 2007
[Probing of contacts between EcoRII DNA methyltransferase and DNA using substrate analogs and molecular modeling].
Kudan EV, Brevnov MG, Subach OM, Rechkoblit OA, Buĭnitskiĭ IaM, Gromova ES
Mol Biol (Mosk). 2007
A model of restriction endonuclease MvaI in complex with DNA: a template for interpretation of experimental data and a guide for specificity engineering.
Kosinski J, Kubareva E, Bujnicki JM
Proteins. 2007
Identification of a missing sequence and functionally important residues of 16S rRNA:m(1)A1408 methyltransferase KamB that causes bacterial resistance to aminoglycoside antibiotics.
Koscinski L, Feder M, Bujnicki JM
Cell Cycle. 2007
Identification of a single HNH active site in type IIS restriction endonuclease Eco31I
Jakubauskas A, Giedriene J, Bujnicki JM, Janulaitis A
J Mol Biol. 2007
Type II restriction endonuclease R.Eco29kI is a member of the GIY-YIG nuclease superfamily.
Ibryashkina EM, Zakharova MV, Baskunov VB, Bogdanova ES, Nagornykh MO, Den\'mukhamedov MM, Melnik BS, Kolinski A, Gront D, Feder M, Solonin AS, Bujnicki JM
BMC Struct Biol. 2007
Phylogenetic analysis of haloalkane dehalogenases.
Chovancová E, Kosinski J, Bujnicki JM, Damborský J
Proteins. 2007
Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.
Issat T, Nowis D, Legat M, Makowski M, Klejman MP, Urbanski J, Skierski J, Koronkiewicz M, Stoklosa T, Brzezinska A, Bil J, Gietka J, Jakóbisiak M, Golab J
Int J Oncol. 2007
MDM2 chaperones the p53 tumor suppressor.
Wawrzynow B, Zylicz A, Wallace M, Hupp T, Zylicz M.
J Biol Chem. 2007
Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.
Issat T, Nowis D, Legat M, Makowski M, Klejman MP, Urbanski J, Skierski J, Koronkiewicz M, Stoklosa T, Brzezinska A, Bil J, Gietka J, Jakóbisiak M, Golab J
Int J Oncol. 2007
2006
Ocena sprawności ruchowej polskich stulatków – wybrane zagadnienia
Kupisz-Urbańska M, Broczek K, Mossakowska M
Gerontologia Polska. 2006
Jak często i jak dużo palili polscy stulatkowie
Mossakowska M, Broczek K, Rajska-Neumann A, Wieczorowska-Tobis K
Przegląd Lekarski. 2006
Ocena stanu uzębienia i użytkowych uzupełnień protetycznych polskich ludzi długowiecznych
Pawlinska-Chmara R, Mossakowska M
Ann Univ M. Curie-Sklodowska. 2006
Analiza leukocytów krwi obwodowej osób stuletnich
Podkówka-Sieczka R, Niemir Z, Mossakowska M, Sawiński K, Wieczorowska-Tobis K
Przegląd Lekarski. 2006
Czy istnieje związek między stężeniem w surowicy interleukiny-8 i zaburzeniami funkcji poznawczych u osób stuletnich?
Styczyński A, Wieczorowska-Tobis K, Niemir Z, Podkówka R, Mossakowska M
Przegląd Lekarski. 2006
Can an increased level of circulating IL-8 be a predictor of human longevity?
Wieczorowska-Tobis K, Niemir ZI, Podkówka R, Korybalska K, Mossakowska M, Breborowicz A
Med Sci Monit. 2006
Correlation between the level of cytogenetic aberrations in cultured human lymphocytes and the age and gender of donors
Wojda A, Zietkiewicz E, Mossakowska M, Pawłowski W, Skrzypczak K, Witt M
J Gerontol A Biol Sci Med Sci. 2006
Characteristics of nutrition among centenarians living in Warsaw
Pietruszka B, Kollajtis-Dolowy A, Szulc K, Kaluza J, Broczek K, Pawlinska-Chmara R, Mossakowska M
Pol J Food Nutr Sci. 2006
Functional abilities and antioxidant defense status in female centenarians
Kempa K, Kłapcińska B, Mossakowska M, Broczek K, Sadowska-Krępa E, Derejczyk J, Kimsa E
Annales Universitatis Mariae Curie-Skłaodowska. 2006
Glutamine-dependent NAD+ synthetase. How a two-domain, three-substrate enzyme avoids waste.
Wojcik M, Seidle HF, Bieganowski P, Brenner C
J Biol Chem. 2006
The growing role of mTOR in neuronal development and plasticity
Jaworski J, Sheng M
Mol Neurobiol. 2006
Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization.
Nolan EM, Ryu JW, Jaworski J, Feazell RP, Sheng M, Lippard SJ
J Am Chem Soc. 2006
Increased estrogen receptor beta expression correlates with decreased spine formation in the rat hippocampus
Szymczak S, Kalita K, Jaworski J, Mioduszewska B, Savonenko A, Markowska A, Merchenthaler I, Kaczmarek L
Hippocampus. 2006
Pulling single bacteriorhodopsin out of a membrane: Comparison of simulation and experiment.
Cieplak M, Filipek S, Janovjak H, Krzyśko KA
Biochim Biophys Acta. 2006
Linear patterns of Alzheimer's disease mutations along alpha-helices of presenilins as a tool for PS-1 model construction
Jozwiak K, Zekanowski C, Filipek S
J Neurochem. 2006
Arrestin interaction with rhodopsin: conceptual models.
Modzelewska A, Filipek S, Palczewski K, Park PS
Cell Biochem Biophys. 2006
Detecting molecular interactions that stabilize native bovine rhodopsin
Tanuj Sapra K, Park PS, Filipek S, Engel A, Müller DJ, Palczewski K
J Mol Biol. 2006
Two novel presenilin 1 gene mutations connected with frontotemporal dementia-like clinical phenotype: genetic and bioinformatic assessment.
Zekanowski C, Golan MP, Krzyśko KA, Lipczyńska-Łojkowska W, Filipek S, Kowalska A, Rossa G, Pepłońska B, Styczyńska M, Maruszak A, Religa D, Wender M, Kulczycki J, Barcikowska M, Kuźnicki J.
Exp Neurol.. 2006
Autosomal recessive retinitis pigmentosa and E150K mutation in the opsin gene.
Zhu L, Imanishi Y, Filipek S, Alekseev A, Jastrzebska B, Sun W, Saperstein DA, Palczewski K
J Biol Chem. 2006
Electrostatic model of bond dissociation energies in polyhalogen methanes
Jaworski JS, Cembor M, Koliński M
J Phys Org Chem. 2006
Calretinin, an EF-hand calcium-binding proteins, binds zinc and Cooper
Groves P, Palczewska M, Kuznicki J
Calcium Binding Proteins. 2006
Binding and functional characteristics of two E-box motifs within the S100A6 (calcyclin) gene promoter.
Leśniak W, Kuźnicki J
J Cell Biochem. 2006
Density of Sgt1-immunopositive neurons is decreased in the cerebral cortex of Alzheimer's disease brain.
Spiechowicz M, Bernstein HG, Dobrowolny H, Leśniak W, Mawrin C, Bogerts B, Kuźnicki J, Filipek A
Neurochem Int. 2006
Neuroendocrine control of metabolic homeostasis in Polish centenarians
Baranowska B, Bik W, Baranowska-Bik A, Wolinska-Witort E, Szybinska A, Martynska L, Chmielowska M
J Physiol Pharmacol. 2006
The relationship between adiponectin levels and metabolic status in centenarian, early elderly, young and obese women
Bik W, Baranowska-Bik A, Wolinska-Witort E, Martynska L, Chmielowska M, Szybinska A, Broczek K, Baranowska B
Neuro Endocrinol Lett. 2006
Ca2+-independent binding and cellular expression profiles question a significant role of calmyrin in transduction of Ca2+-signals to Alzheimer's disease-related presenilin 2 in forebrain
Blazejczyk M, Wojda U, Sobczak A, Spilker C, Bernstein HG, Gundelfinger ED, Kreutz MR, Kuznicki J
Biochim Biophys Acta. 2006
Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease
Bochtler M, Szczepanowski RH, Tamulaitis G, Grazulis S, Czapinska H, Manakova E, Siksnys V
EMBO J. 2006
Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.
Zegers I, Gigot D, van Vliet F, Tricot C, Aymerich S, Bujnicki JM, Kosinski J, Droogmans L
Nucleic Acids Res. 2006
Complete cap 4 formation is not required for viability in Trypanosoma brucei.
Zamudio JR, Mittra B, Zeiner GM, Feder M, Bujnicki JM, Sturm NR, Campbell DA
Eukaryot Cell. 2006
Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis.
Tkaczuk KL, Obarska A, Bujnicki JM
BMC Evol Biol. 2006
Theoretical model of restriction endonuclease HpaI in complex with DNA, predicted by fold recognition and validated by site-directed mutagenesis.
Skowronek KJ, Kosinski J, Bujnicki JM
Proteins. 2006
Curcumin induces caspase-3-dependent apoptotic pathway but inhibits DNA fragmentation factor 40/caspase-activated DNase endonuclease in human Jurkat cells.
Sikora E, Bielak-Zmijewska A, Magalska A, Piwocka K, Mosieniak G, Kalinowska M, Widlak P, Cymerman IA, Bujnicki JM
Mol Cancer Ther. 2006
Evaluation of molecular models for the affinity maturation of antibodies: roles of cytosine deamination by AID and DNA repair.
Samaranayake M, Bujnicki JM, Carpenter M, Bhagwat AS
Chem Rev. 2006
The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase.
Purta E, van Vliet F, Tkaczuk KL, Dunin-Horkawicz S, Mori H, Droogmans L, Bujnicki JM
BMC Mol Biol. 2006
Structural model for the multisubunit Type IC restriction-modification DNA methyltransferase M.EcoR124I in complex with DNA.
Obarska A, Blundell A, Feder M, Vejsadová S, Sisáková E, Weiserová M, Bujnicki JM, Firman K
Nucleic Acids Res. 2006
Casein kinases phosphorylate multiple residues spanning the entire hnRNP K length.
Mikula M, Karczmarski J, Dzwonek A, Rubel T, Hennig E, Dadlez M, Bujnicki JM, Bomsztyk K, Ostrowski J
Biochim Biophys Acta. 2006
The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol.
Metz J, Wächter A, Schmidt B, Bujnicki JM, Schwappach B
J Biol Chem. 2006
Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa.
Klimek-Tomczak K, Mikula M, Dzwonek A, Paziewska A, Karczmarski J, Hennig E, Bujnicki JM, Bragoszewski P, Denisenko O, Bomsztyk K, Ostrowski J
Br J Cancer. 2006
Binding of the low-density lipoprotein by streptococcal collagen-like protein Scl1 of Streptococcus pyogenes.
Han R, Caswell CC, Lukomska E, Keene DR, Pawlowski M, Bujnicki JM, Kim JK, Lukomski S
Mol Microbiol. 2006
Characterization of prmt7alpha and beta isozymes from Chinese hamster cells sensitive and resistant to topoisomerase II inhibitors.
Gros L, Renodon-Cornière A, de Saint Vincent BR, Feder M, Bujnicki JM, Jacquemin-Sablon A
Biochim Biophys Acta. 2006
Helicobacter pylori protein oxidation influences the colonization process.
Godlewska R, Dzwonek A, Mikuła M, Ostrowski J, Pawłowski M, Bujnicki JM, Jagusztyn-Krynicka EK
Int J Med Microbiol. 2006
THUMP from archaeal tRNA:m22G10 methyltransferase, a genuine autonomously folding domain.
Gabant G, Auxilien S, Tuszynska I, Locard M, Gajda MJ, Chaussinand G, Fernandez B, Dedieu A, Grosjean H, Golinelli-Pimpaneau B, Bujnicki JM, Armengaud J
Nucleic Acids Res. 2006
Phylogenomic analysis of the GIY-YIG nuclease superfamily.
Dunin-Horkawicz S, Feder M, Bujnicki JM
BMC Genomics. 2006
Identification of a new subfamily of HNH nucleases and experimental characterization of a representative member, HphI restriction endonuclease
Cymerman IA, Obarska A, Skowronek KJ, Lubys A, Bujnicki JM
Proteins. 2006
Sequence-dependent enhancement of hydrolytic deamination of cytosines in DNA by the restriction enzyme PspGI.
Carpenter M, Divvela P, Pingoud V, Bujnicki J, Bhagwat AS
Nucleic Acids Res. 2006
Functional analysis of amino acid residues at the dimerisation interface of KpnI DNA methyltransferase.
Bheemanaik S, Bujnicki JM, Nagaraja V, Rao DN
Biol Chem. 2006
MODOMICS: a database of RNA modification pathways.
Dunin-Horkawicz S, Czerwoniec A, Gajda MJ, Feder M, Grosjean H, Bujnicki JM
Nucleic Acids Res. 2006
Synthetic lethal and biochemical analyses of NAD and NADH kinases in Saccharomyces cerevisiae establish separation of cellular functions.
Bieganowski P, Seidle HF, Wojcik M, Brenner C
J Biol Chem. 2006
Glutamine-dependent NAD+ synthetase. How a two-domain, three-substrate enzyme avoids waste.
Wojcik M, Seidle HF, Bieganowski P, Brenner C
J Biol Chem. 2006
High guanine and cytosine content increases mRNA levels in mammalian cells.
Kudla G, Lipinski L, Caffin F, Helwak A, Zylicz M.
PLoS Biol. 2006
Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis.
Galazka G, Stasiolek M, Walczak A, Jurewicz A, Zylicz A, Brosnan CF, Raine CS, Selmaj KW
J Immunol. 2006
2005
Hematopoietic chimerism after allogeneic stem cell transplantation: a comparison of quantitative analysis by automated DNA sizing and fluorescent in situ hybridization
Jólkowska J, Pieczonka A, Strabel T, Boruczkowski D, Wachowiak J, Bader P, Witt M
BMC Blood Disord. 2005
Anthropometric chest structure of Polish centenarians
Broczek KM, Pawlińska-Chmara R, Kupisz-Urbańska M, Mossakowska M
J Physiol Pharmacol. 2005
Organization of rhodopsin molecules in native membranes of rod cells--an old theoretical model compared to new experimental data.
Filipek S
J Mol Model. 2005
Functional oligomers of rhodopsin – a G protein-coupled receptor template
Filipek S, Modzelewska A, Krzysko KA
Joint Meeting on Medical Chemistry. 2005
A novel GCAP1 missense mutation (L151F) in a large family with autosomal dominant cone-rod dystrophy (adCORD)
Sokal I, Dupps WJ, Grassi MA, Brown J Jr, Affatigato LM, Roychowdhury N, Yang L, Filipek S, Palczewski K, Stone EM, Baehr W
Invest Ophthalmol Vis Sci. 2005
The Alzheimer disease-related calcium-binding protein Calmyrin is present in human forebrain with an altered distribution in Alzheimer's as compared to normal ageing brains
Bernstein HG, Blazejczyk M, Rudka T, Gundelfinger ED, Dobrowolny H, Bogerts B, Kreutz MR, Kuznicki J, Wojda U
Neuropathol Appl Neurobiol. 2005
The modular structure of SIP facilitates its role in stabilizing multiprotein assemblies
Bhattacharya S, Lee YT, Michowski W, Jastrzebska B, Filipek A, Kuznicki J, Chazin WJ
Biochemistry. 2005
Calcyclin (S100A6) expression is stimulated by agents evoking oxidative stress via the antioxidant response element.
Leśniak W, Szczepańska A, Kuźnicki J.
Biochim Biophys Acta. 2005
Characterization of calretinin I-II as an EF-hand, Ca2+, H+-sensing domain
Palczewska M, Batta G, Groves P, Linse S, Kuznicki J
Protein Sci. 2005
Genetic alterations in accelerated ageing syndromes. Do they play a role in natural ageing?
Puzianowska-Kuznicka M, Kuznicki J.
Int J Biochem Cell Biol. 2005
Calcium-binding calmyrin forms stable covalent dimers in vitro, but in vivo is found in monomeric form.
Sobczak A, Blazejczyk M, Piszczek G, Zhao G, Kuznicki J, Wojda U.
Acta Biochim Pol. 2005
The -22c/t polymorphism in presenilin 1 gene is not connected with late-onset and early-onset familial Alzheimer's disease in Poland
Zekanowski C, Religa D, Safranow K, Maruszak A, Dziedziejko V, Styczyńska M, Gacia M, Golan M, Pepłońska B, Chlubek D, Kuźnicki J, Barcikowska M
J Neural Transm. 2005
Characterization of the HslU chaperone affinity for HslV protease
Azim MK, Goehring W, Song HK, Ramachandran R, Bochtler M, Goettig P
Protein Sci. 2005
Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene
Dandanell G,Szczepanowski RH, Kierdaszuk B, Shugar D, Bochtler M
J Mol Biol. 2005
A comparison of staphostatin B with standard mechanism serine protease inhibitors
Filipek R, Potempa J, Bochtler M
J Biol Chem. 2005
Structure of the metal-independent restriction enzyme BfiI reveals fusion of a specific DNA-binding domain with a nonspecific nuclease.
Grazulis S, Manakova E, Roessle M, Bochtler M, Tamulaitiene G, Huber R, Siksnys V
Proc Natl Acad Sci U S A. 2005
Molecular machines for protein degradation.
Groll M, Bochtler M, Brandstetter H, Clausen T, Huber R
Chembiochem. 2005
Pseudomonas aeruginosa LD-carboxypeptidase, a serine peptidase with a Ser-His-Glu triad and a nucleophilic elbow.
Korza HJ, Bochtler M
J Biol Chem. 2005
Staphylococcus aureus aminopeptidase S is a founding member of a new peptidase clan
Odintsov SG, Sabała I, Bourenkov G, Rybin V, Bochtler M
J Biol Chem. 2005
Substrate access to the active sites in aminopeptidase T, a representative of a new metallopeptidase clan.
Odintsov SG, Sabała I, Bourenkov G, Rybin V, Bochtler M
J Mol Biol. 2005
Crystal structure of a fragment of mouse ubiquitin-activating enzyme.
Szczepanowski RH, Filipek R, Bochtler M
J Biol Chem. 2005
Fighting an enemy within: cytoplasmic inhibitors of bacterial cysteine proteases
Potempa J, Golonka E, Filipek R, Shaw LN
Mol Microbiol. 2005
Peptydoglycan amidase MepA is a LAS metallopeptidase
Marcyjaniak M, Odintsov SG, Sabala I, Bochtler M
J Biol Chem. 2005
Cloning and preliminary characterization of a GATC-specific beta2-class DNA:m6A methyltransferase encoded by transposon Tn1549 from Enterococcus spp.
Radlińska M, Piekarowicz A, Galimand M, Bujnicki JM
Pol J Microbiol. 2005
Analysis of the quaternary structure of the MutL C-terminal domain.
Kosinski J, Steindorf I, Bujnicki JM, Giron-Monzon L, Friedhoff P
J Mol Biol. 2005
FRankenstein becomes a cyborg: the automatic recombination and realignment of fold recognition models in CASP6.
Kosinski J, Gajda MJ, Cymerman IA, Kurowski MA, Pawlowski M, Boniecki M, Obarska A, Papaj G, Sroczynska-Obuchowicz P, Tkaczuk KL, Sniezynska P, Sasin JM, Augustyn A, Bujnicki JM, Feder M
Proteins. 2005
Molecular modeling of a psychrophilic β-galactosidase
Tkaczuk KL, Bujnicki JM, Bialkowska A, Bielecki S, Turkiewicz M, Cieslinski H, Kur J
Biocatal Biotransform. 2005
Identification of amino acids important for target recognition by the DNA:m5C methyltransferase M.NgoPII by alanine-scanning mutagenesis of residues at the protein-DNA interface.
Radlinska M, Kondrzycka-Dada A, Piekarowicz A, Bujnicki JM.
Proteins. 2005
Characterization of new DsbB-like thiol-oxidoreductases of Campylobacter jejuni and Helicobacter pylori and classification of the DsbB family based on phylogenomic, structural and functional criteria.
Raczko AM, Bujnicki JM, Pawlowski M, Godlewska R, Lewandowska M, Jagusztyn-Krynicka EK
Microbiology. 2005
Sequence-structure-function relationships of a tRNA (m7G46) methyltransferase studied by homology modeling and site-directed mutagenesis.
Purta E, van Vliet F, Tricot C, De Bie LG, Feder M, Skowronek K, Droogmans L, Bujnicki JM
Proteins. 2005
Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA.
Purushothaman SK, Bujnicki JM, Grosjean H, Lapeyre B.
Mol Cell Biol. 2005
Specificity changes in the evolution of type II restriction endonucleases: a biochemical and bioinformatic analysis of restriction enzymes that recognize unrelated sequences
Pingoud V, Sudina A, Geyer H, Bujnicki JM, Lurz R, Lüder G, Morgan R, Kubareva E, Pingoud A
J Biol Chem. 2005
Identification of base-specific contacts in protein-DNA complexes by photocrosslinking and mass spectrometry: a case study using the restriction endonuclease SsoII
Pingoud V, Geyer H, Geyer R, Kubareva E, Bujnicki JM, Pingoud A
Mol Biosyst. 2005
Inference of relationships in the 'twilight zone' of homology using a combination of bioinformatics and site-directed mutagenesis: a case study of restriction endonucleases Bsp6I and PvuII
Pawlak SD, Radlinska M, Chmiel AA, Bujnicki JM, Skowronek KJ
Nucleic Acids Res. 2005
Analysis of the quaternary structure of the MutL C-terminal domain.
Kosinski J, Steindorf I, Bujnicki JM, Giron-Monzon L, Friedhoff P
J Mol Biol. 2005
The PD-(D/E)XK superfamily revisited: identification of new members among proteins involved in DNA metabolism and functional predictions for domains of (hitherto) unknown function.
Kosinski J, Feder M, Bujnicki JM
BMC Bioinformatics. 2005
Generalized protein structure prediction based on combination of fold-recognition with de novo folding and evaluation of models.
Koliński A, Bujnicki JM
Proteins. 2005
Discovery of a novel restriction endonuclease by genome comparison and application of a wheat-germ-based cell-free translation assay: PabI (5'-GTA/C) from the hyperthermophilic archaeon Pyrococcus abyssi
Ishikawa K, Watanabe M, Kuroita T, Uchiyama I, Bujnicki JM, Kawakami B, Tanokura M, Kobayashi I
Nucleic Acids Res. 2005
Identification of a new family of putative PD-(D/E)XK nucleases with unusual phylogenomic distribution and a new type of the active site.
Feder M, Bujnicki JM
BMC Genomics. 2005
DNase II is a member of the phospholipase D superfamily.
Cymerman IA, Meiss G, Bujnicki JM
Bioinformatics. 2005
A theoretical model of restriction endonuclease NlaIV in complex with DNA, predicted by fold recognition and validated by site-directed mutagenesis and circular dichroism spectroscopy.
Chmiel AA, Radlinska M, Pawlak SD, Krowarsch D, Bujnicki JM, Skowronek KJ
Protein Eng Des Sel. 2005
A homology model of restriction endonuclease SfiI in complex with DNA
Chmiel AA, Bujnicki JM, Skowronek KJ
BMC Struct Biol. 2005
Mva1269I: a monomeric type IIS restriction endonuclease from Micrococcus varians with two EcoRI- and FokI-like catalytic domains.
Armalyte E, Bujnicki JM, Giedriene J, Gasiunas G, Kosiński J, Lubys A
J Biol Chem. 2005
Mutational analysis of BTAF1-TBP interaction: BTAF1 can rescue DNA-binding defective TBP mutants.
Klejman MP, Zhao X, van Schaik FM, Herr W, Timmers HT
Nucleic Acids Res. 2005
Psc3 cohesin of Schizosaccharomyces pombe: cell cycle analysis and identification of three distinct isoforms.
Ilyushik E, Pryce DW, Walerych D, Riddell T, Wakeman JA, McInerny CJ, McFarlane RJ
Biol Chem. 2005
Characterization of testis-specific serine-threonine kinase 3 and its activation by phosphoinositide-dependent kinase-1-dependent signalling.
Bucko-Justyna M, Lipinski L, Burgering BM, Trzeciak L
FEBS J. 2005
2004
Primary ciliary dyskinesia: genes, candidate genes and chromosomal regions
Geremek M, Witt M
J Appl Genet. 2004
Apparent X-linked primary ciliary dyskinesia associated with retinitis pigmentosa and a hearing loss
Krawczyński MR, Dmeńska H, Witt M
J Appl Genet. 2004
Mikrojądra w komórkach człowieka - powstawanie, zawartość oraz wykorzystanie diagnostyczne i prognostyczne
Lubka M, Wojda A, Witt M
Postępy Biol Kom. 2004
Kidney function estimated with different formulas in centenarians
Wieczorowska-Tobis K, Niemir ZI, Guzik P, Mossakowska M
Rocz Akad Med Bialymst. 2004
Blood pressure in centenarians in Poland
Zyczkowska J, Klich-Raczka A, Mossakowska M, Gasowski J, Wieczorowska-Tobis K, Grodzicki T
J Hum Hypertens. 2004
A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface
Filipek S, Krzysko KA , Fotiadis D, Liang Y, Saperstein DA, Engel A, Palczewski K
Photochem Photobiol Sci. 2004
The G protein-coupled receptor rhodopsin in the native membrane
Fotiadis D, Liang Y, Filipek S, Saperstein DA, Engel A, Palczewski K
FEBS Lett. 2004
Diversity of guanylate cyclase-activating proteins (GCAPs) in teleost fish: characterization of three novel GCAPs (GCAP4, GCAP5, GCAP7) from zebrafish (Danio rerio) and prediction of eight GCAPs (GCAP1-8) in pufferfish (
Imanishi Y, Yang L, Sokal I, Filipek S, Palczewski K, Baehr W
J Mol Evol. 2004
Functional characterization of rhodopsin monomers and dimers in detergents
Jastrzebska B, Maeda T, Zhu L, Fotiadis D, Filipek S, Engel A, Stenkamp RE, Palczewski K
J Biol Chem. 2004
Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice
Liang Y, Fotiadis D, Maeda T, Maeda A, Modzelewska A, Filipek S, Saperstein DA, Engel A, Palczewski K
J Biol Chem. 2004
Oligomerization of G protein-coupled receptors: past, present, and future.
Park PS, Filipek S, Wells JW, Palczewski K
Biochemistry. 2004
The supramolecular structure of the GPCR rhodopsin in solution and native disc membranes.
Suda K, Filipek S, Palczewski K, Engel A, Fotiadis D
Mol Membr Biol. 2004
A naturally occurring mutation of the opsin gene (T4R) in dogs affects glycosylation and stability of the G protein-coupled receptor.
Zhu L, Jang GF, Jastrzebska B, Filipek S, Pearce-Kelling SE, Aguirre GD, Stenkamp RE, Acland GM, Palczewski K
J Biol Chem. 2004
Calretinin gene promoter activity is differently regulated in neurons and cancer cells. Role of AP2-like cis element and zinc ions
Billing-Marczak K, Ziemińska E, Leśniak W, Łazarewicz JW, Kuźnicki J
Biochim Biophys Acta. 2004
Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain.
Lee YT, Jacob J, Michowski W, Nowotny M, Kuznicki J, Chazin WJ.
J Biol Chem.. 2004
Gene therapy of hematopoietic cells: development of strategies and vectors. (in Polish)
Wojda U.
Postepy Biol Kom. 2004
The E318G substitution in PSEN1 gene is not connected with Alzheimer's disease in a large Polish cohort.
Zekanowski C, Pepłońska B, Styczyńska M, Religa D, Pfeffer A, Czyzewski K, Gabryelewicz T, Szybińska A, Kijanowska-Haładyna B, Kotapka-Minc S, Łuczywek E, Barczak A, Wasiak B, Chodakowska-Zebrowska M, Przekop I, Kuźnicki J, Barcikowska M
Neurosci Lett. 2004
Genetic aspects of Alzheimer's disease
Zekanowski C, Religa D, Graff C, Filipek S, Kuźnicki J
Acta Neurobiol Exp (Wars). 2004
Proliferation and apoptosis of human CD8(+)CD28(+) and CD8(+)CD28(-) lymphocytes during aging
Brzezińska A, Magalska A, Szybińska A, Sikora E
Exp Gerontol. 2004
Similar active sites in lysostaphins and D-Ala-D-Ala metallopeptidases.
Bochtler M, Odintsov SG, Marcyjaniak M, Sabala I
Protein Sci. 2004
Prostaphopain B structure: a comparison of proregion-mediated and staphostatin-mediated protease inhibition
Filipek R, Szczepanowski R, Sabat A, Potempa J, Bochtler M
Biochemistry. 2004
Peptidoglycan amidase MepA is a LAS metallopeptidase
Marcyjaniak M, Odintsov SG, Sabala I, Bochtler M.
J Biol Chem. 2004
Genetic characterization of staphopain genes in Staphylococcus aureus
Golonka E, Filipek R, Sabat A, Sinczak A, Potempa J
Biol Chem. 2004
Probabilistic cross-link analysis and experiment planning for high-throughput elucidation of protein structure.
Ye X, O\'Neil PK, Foster AN, Gajda MJ, Kosinski J, Kurowski MA, Bujnicki JM, Friedman AM, Bailey-Kellogg C
Protein Sci. 2004
Structural and functional characterization of mitochondrial EndoG, a sugar non-specific nuclease which plays an important role during apoptosis.
Schäfer P, Scholz SR, Gimadutdinow O, Cymerman IA, Bujnicki JM, Ruiz-Carrillo A, Pingoud A, Meiss G
J Mol Biol. 2004
COLORADO3D, a web server for the visual analysis of protein structures.
Sasin JM, Bujnicki JM
Nucleic Acids Res. 2004
Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily.
Saravanan M, Bujnicki JM, Cymerman IA, Rao DN, Nagaraja V
Nucleic Acids Res. 2004
A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase
Roovers M, Wouters J, Bujnicki JM, Tricot C, Stalon V, Grosjean H, Droogmans L
Nucleic Acids Res. 2004
Geometric analysis of cross-linkability for protein fold discrimination.
Potluri S, Khan AA, Kuzminykh A, Bujnicki JM, Friedman AM, Bailey-Kellogg C
Pac Symp Biocomput. 2004
Cooperative binding of the hnRNP K three KH domains to mRNA targets.
Paziewska A, Wyrwicz LS, Bujnicki JM, Bomsztyk K, Ostrowski J
FEBS Lett. 2004
Sterol methyltransferase: functional analysis of highly conserved residues by site-directed mutagenesis.
Nes WD, Jayasimha P, Zhou W, Kanagasabai R, Jin C, Jaradat TT, Shaw RW, Bujnicki JM
Biochemistry. 2004
Mutational analysis of basic residues in the N-terminus of the rRNA:m6A methyltransferase ErmC'
Maravić G, Bujnicki JM, Flögel M
Folia Microbiol (Praha). 2004
Homology modeling of the CG-specific DNA methyltransferase SssI and its complexes with DNA and AdoHcy.
Koudan EV, Bujnicki JM, Gromova ES
J Biomol Struct Dyn. 2004
Homology modeling of the CG-specific DNA methyltransferase SssI and its complexes with DNA and AdoHcy.
Koudan EV, Bujnicki JM, Gromova ES
J Biomol Struct Dyn. 2004
Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA.
Bujnicki JM, Oudjama Y, Roovers M, Owczarek S, Caillet J, Droogmans L.
RNA. 2004
Sequence-structure-function studies of tRNA:m5C methyltransferase Trm4p and its relationship to DNA:m5C and RNA:m5U methyltransferases.
Bujnicki JM, Feder M, Ayres CL, Redman KL
Nucleic Acids Res. 2004
N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.
Armengaud J, Urbonavicius J, Fernandez B, Chaussinand G, Bujnicki JM, Grosjean H
J Biol Chem. 2004
Hsp90 chaperones wild-type p53 tumor suppressor protein.
Walerych D, Kudla G, Gutkowska M, Wawrzynow B, Muller L, King FW, Helwak A, Boros J, Zylicz A, Zylicz M.
J Biol Chem. 2004
Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II.
Mycko MP, Cwiklinska H, Szymanski J, Szymanska B, Kudla G, Kilianek L, Odyniec A, Brosnan CF, Selmaj KW.
J Immunol. 2004
Gene conversion and GC-content evolution in mammalian Hsp70.
Kudla G, Helwak A, Lipinski L
Mol Biol Evol. 2004
Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures.
Müller L, Schaupp A, Walerych D, Wegele H, Buchner J
J Biol Chem. 2004
P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma.
Jassem J, Jassem E, Jakóbkiewicz-Banecka J, Rzyman W, Badzio A, Dziadziuszko R, Kobierska-Gulida G, Szymanowska A, Skrzypski M, Zylicz M.
Cancer. 2004
MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC).
Dworakowska D, Jassem E, Jassem J, Peters B, Dziadziuszko R, Zylicz M, Jakóbkiewicz-Banecka J, Kobierska-Gulida G, Szymanowska A, Skokowski J, Roessner A, Schneider-Stock R
Lung Cancer. 2004
2003
Functioning of Polish centenarians
Pruszynski J, Gross R, Mossakowska M, Barcikowska M, Czyzewski K, Derejczyk J, Galus K, Grodzicki T, Jedrkiewicz H, Klich-Raczka A, Kupsc W, Luczywek E, Pfeffer A, Puzianowska-Kuznicka M, Sosnowski M, Styczynska M, Wasiak B, Wieczorowska-Tobis K, Zyczkows
Gerontologia. 2003
The 102-year old woman with translocation (7;12) and infertility in anamnesis
Wojda A, Wolnik-Brzozowska D, Lubka M, Mossakowska M, Witt M
J Appl Genet. 2003
Hypertension and cognitive and functional performance in centenarians
Zyczkowska J, Klich-Raczka A, Wizner B, Mossakowska M, Wieczorowska-Tobis K, Grodzicki T
New Medicine. 2003
Cystic fibrosis--a probable cause of Frédéric Chopin's suffering and death
Majka L, Goździk J, Witt M
J Appl Genet. 2003
The crystallographic model of rhodopsin and its use in studies of other G protein-coupled receptors.
Filipek S, Teller DC, Palczewski K, Stenkamp R
Annu Rev Biophys Biomol Struct. 2003
Atomic-force microscopy: Rhodopsin dimers in native disc membranes
Fotiadis D, Liang Y, Filipek S, Saperstein DA, Engel A, Palczewski K
Nature. 2003
Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation.
Fritze O, Filipek S, Kuksa V, Palczewski K, Hofmann KP, Ernst OP
Proc Natl Acad Sci U S A. 2003
Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes
Liang Y, Fotiadis D, Filipek S, Saperstein DA, Palczewski K, Engel A
J Biol Chem. 2003
Evaluation of the role of the retinal G protein-coupled receptor (RGR) in the vertebrate retina in vivo.
Maeda T, Van Hooser JP, Driessen CA, Filipek S, Janssen JJ, Palczewski K
J Neurochem. 2003
Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin.
Mirzadegan T, Benkö G, Filipek S, Palczewski K
Biochemistry. 2003
Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosa.
Noorwez SM, Kuksa V, Imanishi Y, Zhu L, Filipek S, Palczewski K, Kaushal S
J Biol Chem. 2003
Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin.
Schadel SA, Heck M, Maretzki D, Filipek S, Teller DC, Palczewski K, Hofmann KP
J Biol Chem. 2003
Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins.
Nowotny M, Spiechowicz M, Jastrzebska B, Filipek A, Kitagawa K, Kuznicki J
J Biol Chem. 2003
Calretinin and calbindin D28k have different domain organizations
Palczewska M, Groves P, Batta G, Heise B, Kuźnicki J
Protein Sci. 2003
Strong association between Saitohin gene polymorphism and tau haplotype in the Polish population
Pepłońska B, Zekanowski C, Religa D, Czyzewski K, Styczyńska M, Pfeffer A, Gabryelewicz T, Gołebiowski M, Luczywek E, Wasiak B, Barczak A, Chodakowska M, Barcikowska M, Kuźnicki J
Neurosci Lett. 2003
Mutations in presenilin 1, presenilin 2 and amyloid precursor protein genes in patients with early-onset Alzheimer's disease in Poland
Zekanowski C, Styczyńska M, Pepłońska B, Gabryelewicz T, Religa D, Ilkowski J, Kijanowska-Haładyna B, Kotapka-Minc S, Mikkelsen S, Pfeffer A, Barczak A, Łuczywek E, Wasiak B, Chodakowska-Zebrowska M, Gustaw K, Łaczkowski J, Sobów T, Kuźnicki J, Barcikowsk
Exp Neurol. 2003
Mutation screening of the MAPT and STH genes in Polish patients with clinically diagnosed frontotemporal dementia
Zekanowski C, Pepłońska B, Styczyńska M, Gustaw K, Kuźnicki J, Barcikowska M
Dement Geriatr Cogn Disord. 2003
Alzheimer's disease: between diagnostic, economy and ethic (in Polish)
Zekanowski C, Przyluska-Fiszer A, Barcikowska M
Choroby otępienne. Teoria i praktyka. 2003
Genetic diversity within the R408W phenylketonuria mutation lineages in Europe
Tighe O, Dunican D, O'Neill C, Bertorelle G, Beattie D, Graham C, Zschocke J, Cali F, Romano V, Hrabincova E, Kozak L, Nechyporenko M, Livshits L, Guldberg P, Jurkowska M, Zekanowski C, Perez B, Desviat LR, Ugarte M, Kucinskas V, Knappskog P, Treacy E, N
Hum Mutat. 2003
A novel class of cysteine protease inhibitors: solution structure of staphostatin A from Staphylococcus aureus.
Dubin G, Krajewski M, Popowicz G, Stec-Niemczyk J, Bochtler M, Potempa J, Dubin A, Holak TA
Biochemistry. 2003
The Staphostatin-staphopain complex: a forward binding inhibitor in complex with its target cysteine protease.
Filipek R, Rzychon M, Oleksy A, Gruca M, Dubin A, Potempa J, Bochtler M
J Biol Chem. 2003
Staphostatins resemble lipocalins, not cystatins in fold
Rzychon M, Filipek R, Sabat A, Kosowska K, Dubin A, Potempa J, Bochtler M
Protein Sci. 2003
Experimental evidence for a beta beta alpha-Me-finger nuclease motif to represent the active site of the caspase-activated DNase.
Scholz SR, Korn C, Bujnicki JM, Gimadutdinow O, Pingoud A, Meiss G
Biochemistry. 2003
STRUCLA: a WWW meta-server for protein structure comparison and evolutionary classification.
Sasin JM, Kurowski MA, Bujnicki JM
Bioinformatics. 2003
PspGI, a type II restriction endonuclease from the extreme thermophile Pyrococcus sp.: structural and functional studies to investigate an evolutionary relationship with several mesophilic restriction enzymes
Pingoud V, Conzelmann C, Kinzebach S, Sudina A, Metelev V, Kubareva E, Bujnicki JM, Lurz R, Lüder G, Xu SY, Pingoud A
J Mol Biol. 2003
Sequence-structure-function relationships of Tgs1, the yeast snRNA/snoRNA cap hypermethylase
Mouaikel J, Bujnicki JM, Tazi J, Bordonné R
Nucleic Acids Res. 2003
Mutational analysis defines the roles of conserved amino acid residues in the predicted catalytic pocket of the rRNA:m6A methyltransferase ErmC'
Maravić G, Feder M, Pongor S, Flögel M, Bujnicki JM
J Mol Biol. 2003
Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions
Maravić G, Bujnicki JM, Feder M, Pongor S, Flögel M
Nucleic Acids Res. 2003
Characterization of the cofactor-binding site in the SPOUT-fold methyltransferases by computational docking of S-adenosylmethionine to three crystal structures.
Kurowski MA, Sasin JM, Feder M, Debski J, Bujnicki JM
BMC Bioinformatics. 2003
GeneSilico protein structure prediction meta-server.
Kurowski MA, Bujnicki JM
Nucleic Acids Res. 2003
Phylogenomic identification of five new human homologs of the DNA repair enzyme AlkB.
Kurowski MA, Bhagwat AS, Papaj G, Bujnicki JM
BMC Genomics. 2003
A "FRankenstein's monster" approach to comparative modeling: merging the finest fragments of Fold-Recognition models and iterative model refinement aided by 3D structure evaluation
Kosinski J, Cymerman IA, Feder M, Kurowski MA, Sasin JM, Bujnicki JM
Proteins. 2003
Anti-HIV-1 activity of 3-deaza-adenosine analogs. Inhibition of S-adenosylhomocysteine hydrolase and nucleotide congeners.
Gordon RK, Ginalski K, Rudnicki WR, Rychlewski L, Pankaskie MC, Bujnicki JM, Chiang PK
Eur J Biochem. 2003
Molecular phylogenetics of the RrmJ/fibrillarin superfamily of ribose 2'-O-methyltransferases
Feder M, Pas J, Wyrwicz LS, Bujnicki JM
Gene. 2003
Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures.
Droogmans L, Roovers M, Bujnicki JM, Tricot C, Hartsch T, Stalon V, Grosjean H
Nucleic Acids Res. 2003
The yggH gene of Escherichia coli encodes a tRNA (m7G46) methyltransferase.
De Bie LG, Roovers M, Oudjama Y, Wattiez R, Tricot C, Stalon V, Droogmans L, Bujnicki JM
J Bacteriol. 2003
Structure, evolution, and inhibitor interaction of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.
Bujnicki JM, Prigge ST, Caridha D, Chiang PK
Proteins. 2003
Fold recognition, homology modeling, docking simulations, kinetics analysis and mutagenesis of ATP/CTP:tRNA nucleotidyltransferase from Methanococcus jannaschii.
Bujnicki JM, Albert MA, Nelson DJ, Thurlow DL
Proteins. 2003
Crystallographic and bioinformatic studies on restriction endonucleases: inference of evolutionary relationships in the "midnight zone" of homology
Bujnicki JM
Curr Protein Pept Sci. 2003
2002
Discrepancies in creatinine clearance in centenarians when calculated by two different mathematical formulas
Wieczorowska-Tobis K, Mossakowska M, Niemir Z, Breborowicz A, Oreopoulos DG
Nephrol Dial Transplant. 2002
Anemia in centenarians
Wieczorowska-Tobis K, Niemir Z, Mossakowska M, Klich-Raczka A, Zyczkowska J
J Am Geriatr Soc. 2002
Biochemical and physiological properties of rhodopsin regenerated with 11-cis-6-ring- and 7-ring-retinals.
Kuksa V, Bartl F, Maeda T, Jang GF, Ritter E, Heck M, Van Hooser JP, Liang Y, Filipek S, Gelb MH, Hofmann KP, Palczewski K
J Biol Chem. 2002
CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family
Filipek A, Jastrzebska B, Nowotny M, Kuznicki J.
J Biol Chem. 2002
Ca2+-dependent translocation of the calcyclin-binding protein in neurons and neuroblastoma NB-2a cells
Filipek A, Jastrzebska B, Nowotny M, Kwiatkowska K, Hetman M, Surmacz L, Wyroba E,Kuznicki J
J Biol Chem. 2002
Atypical PKU - treatment effectiveness
Cabalska B, Nowacka M, Nowaczewska I, Zekanowski C, Zorska K
Medycyna Wieku Rozwojowego VI. 2002
Novel PKU treatment methods
Zekanowski C, Gizewska M, Nowacka M, Cabalska B
Medycyna Wieku Rozwojowego. 2002
Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY)
Ramachandran R, Hartmann C, Song HK, Huber R, Bochtler M
Proc Natl Acad Sci U S A. 2002
Angiogenesis inhibitors specific for methionine aminopeptidase 2 as drugs for malaria and leishmaniasis
Zhang P, Nicholson DE, Bujnicki JM, Su X, Brendle JJ, Ferdig M, Kyle DE, Milhous WK, Chiang PK
J Biomed Sci. 2002
Streptococcal Scl1 and Scl2 proteins form collagen-like triple helices.
Xu Y, Keene DR, Bujnicki JM, Höök M, Lukomski S
J Biol Chem. 2002
Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop
Pintard L, Lecointe F, Bujnicki JM, Bonnerot C, Grosjean H, Lapeyre B
EMBO J. 2002
MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase
Pintard L, Bujnicki JM, Lapeyre B, Bonnerot C
EMBO J. 2002
Evolutionary relationship between different subgroups of restriction endonucleases.
Pingoud V, Kubareva E, Stengel G, Friedhoff P, Bujnicki JM, Urbanke C, Sudina A, Pingoud A
J Biol Chem. 2002
The hppA gene of Helicobacter pylori encodes the class C acid phosphatase precursor
Godlewska R, Bujnicki JM, Ostrowski J, Jagusztyn-Krynicka EK
FEBS Lett. 2002
Fold-recognition detects an error in the Protein Data Bank
Bujnicki J, Rychlewski L, Fischer D
Bioinformatics. 2002
In silico identification, structure prediction and phylogenetic analysis of the 2'-O-ribose (cap 1) methyltransferase domain in the large structural protein of ssRNA negative-strand viruses
Bujnicki JM, Rychlewski L
Protein Eng. 2002
RNA:(guanine-N2) methyltransferases RsmC/RsmD and their homologs revisited--bioinformatic analysis and prediction of the active site based on the uncharacterized Mj0882 protein structure
Bujnicki JM, Rychlewski L
BMC Bioinformatics. 2002
Fold-recognition analysis predicts that the Tag protein family shares a common domain with the helix-hairpin-helix DNA glycosylases
Bujnicki JM, Rychlewski L
DNA Repair (Amst). 2002
Bioinformatic analyses of the tRNA: (guanine 26, N2,N2)-dimethyltransferase (Trm1) family
Bujnicki JM, Leach RA, Debski J, Rychlewski L
J Mol Microbiol Biotechnol. 2002
Errors in the D. radiodurans large ribosomal subunit structure detected by protein fold-recognition and structure validation tools
Bujnicki JM, Feder M, Rychlewski L, Fischer D
FEBS Lett. 2002
Structure prediction and phylogenetic analysis of a functionally diverse family of proteins homologous to the MT-A70 subunit of the human mRNA:m(6)A methyltransferase
Bujnicki JM, Feder M, Radlinska M, Blumenthal RM
J Mol Evol. 2002
Sequence analysis and structure prediction of 23S rRNA:m1G methyltransferases reveals a conserved core augmented with a putative Zn-binding domain in the N-terminus and family-specific elaborations in the C-terminus
Bujnicki JM, Blumenthal RM, Rychlewski L
J Mol Microbiol Biotechnol. 2002
Sequence permutations in the molecular evolution of DNA methyltransferases
Bujnicki JM
BMC Evol Biol. 2002
AP2-like cis element is required for calretinin gene promoter activity in cells of neuronal phenotype differentiated from multipotent human cell line DEV.
Billing-Marczak K, Buzanska L, Winsky L, Nowotny M, Rudka T, Isaacs K, Belin MF, Kuznicki J.
Biochim Biophys Acta. 2002
2001
Plasma creatine and sodium abnormalities in Polish centenarians
Wieczorowska-Tobis K, Mossakowska M, Niemir Z, Breborowicz A, Oreopoulos DG
Ann Acad Med Gedan. 2001
Structural and biochemical characterization of neuronal calretinin domain I-II (residues 1-100). Comparison to homologous calbindin D28k domain I-II (residues 1-93)
Palczewska M, Groves P, Ambrus A, Kaleta A, Kövér KE, Batta G, Kuźnicki J.
Eur J Biochem.. 2001
Site-directed mutagenesis defines the catalytic aspartate in the active site of the atypical DNA: m4C methyltransferase M.NgoMXV
Radlinska M, Bujnicki JM
Acta Microbiol Pol. 2001
Cloning of enterohemorrhagic Escherichia coli phage VT-2 dam methyltransferase
Radlinska M, Bujnicki JM
Acta Microbiol Pol. 2001
Pcons: a neural-network-based consensus predictor that improves fold recognition
Lundström J, Rychlewski L, Bujnicki J, Elofsson A
Protein Sci. 2001
The herpesvirus alkaline exonuclease belongs to the restriction endonuclease PD-(D/E)XK superfamily: insight from molecular modeling and phylogenetic analysis.
Bujnicki JM, Rychlewski L
Virus Genes. 2001
Grouping together highly diverged PD-(D/E)XK nucleases and identification of novel superfamily members using structure-guided alignment of sequence profiles.
Bujnicki JM, Rychlewski L
J Mol Microbiol Biotechnol. 2001
Reassignment of specificities of two cap methyltransferase domains in the reovirus lambda 2 protein
Bujnicki JM, Rychlewski L
Genome Biol. 2001
Unusual evolutionary history of the tRNA splicing endonuclease EndA: relationship to the LAGLIDADG and PD-(D/E)XK deoxyribonucleases.
Bujnicki JM, Rychlewski L
Protein Sci. 2001
Identification of a PD-(D/E)XK-like domain with a novel configuration of the endonuclease active site in the methyl-directed restriction enzyme Mrr and its homologs
Bujnicki JM, Rychlewski L
Gene. 2001
Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases
Bujnicki JM, Rychlewski L
Acta Microbiol Pol. 2001
Three-dimensional modeling of the I-TevI homing endonuclease catalytic domain, a GIY-YIG superfamily member, using NMR restraints and Monte Carlo dynamics.
Bujnicki JM, Rotkiewicz P, Kolinski A, Rychlewski L
Protein Eng. 2001
Cloning of the Haemophilus influenzae Dam methyltransferase and analysis of its relationship to the Dam methyltransferase encoded by the HP1 phage
Bujnicki JM, Radlinska M, Zaleski P, Piekarowicz A
Acta Biochim Pol. 2001
Polyphyletic evolution of type II restriction enzymes revisited: two independent sources of second-hand folds revealed
Bujnicki JM, Radlinska M, Rychlewski L
Trends Biochem Sci. 2001
Cloning and characterization of M.LmoA118I, a novel DNA:m4C methyltransferase from the Listeria monocytogenes phage A118, a close homolog of M.NgoMXV
Bujnicki JM, Radlinska M
Acta Microbiol Pol. 2001
mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships
Bujnicki JM, Feder M, Radlinska M, Rychlewski L
BMC Bioinformatics. 2001
LiveBench-2: large-scale automated evaluation of protein structure prediction servers.
Bujnicki JM, Elofsson A, Fischer D, Rychlewski L
Proteins. 2001
LiveBench-1: continuous benchmarking of protein structure prediction servers
Bujnicki JM, Elofsson A, Fischer D, Rychlewski L
Protein Sci. 2001
Structure prediction meta server
Bujnicki JM, Elofsson A, Fischer D, Rychlewski L
Bioinformatics. 2001
A model of structure and action of Sau3AI restriction endonuclease that comprises two MutH-like endonuclease domains within a single polypeptide.
Bujnicki JM
Acta Microbiol Pol. 2001
Understanding the evolution of restriction-modification systems: clues from sequence and structure comparisons.
Bujnicki JM
Acta Biochim Pol. 2001
In silico analysis of the tRNA:m1A58 methyltransferase family: homology-based fold prediction and identification of new members from Eubacteria and Archaea
Bujnicki JM
FEBS Lett. 2001
Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.
King FW, Wawrzynow A, Höhfeld J, Zylicz M.
EMBO J. 2001
Types and localisation of p53 gene mutations: a report on 332 non-small cell lung cancer patients.
Jassem E, Nikliński J, Rosell R, Niklińska W, Jakóbkiewicz J, Monzo M, Chyczewski L, Kobierska G, Skokowski J, Zylicz M, Jassem J
Lung Cancer. 2001
DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction.
Genevaux P, Wawrzynow A, Zylicz M, Georgopoulos C, Kelley WL
J Biol Chem. 2001
Multitemperature single-strand conformation polymorphism.
Kaczanowski R, Trzeciak L, Kucharczyk K
Electrophoresis. 2001
Hsp70 interactions with the p53 tumour suppressor protein.
Zylicz M, King FW, Wawrzynow A.
EMBO J. 2001
DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction.
Genevaux P, Wawrzynow A, Zylicz M, Georgopoulos C, Kelley WL
J Biol Chem. 2001
Structure-function analysis of the zinc-binding region of the Clpx molecular chaperone.
Banecki B, Wawrzynow A, Puzewicz J, Georgopoulos C, Zylicz M.
J Biol Chem. 2001
2000
Characterization of the interaction of calcyclin (S100A6) and calcyclin-binding protein.
Nowotny M, Bhattacharya S, Filipek A, Krezel AM, Chazin W, Kuznicki J.
J Biol Chem.. 2000
Calcyclin (S100A6) binding protein (CacyBP) is highly expressed in brain neurons.
Jastrzebska B, Filipek A, Nowicka D, Kaczmarek L, Kuznicki J.
J Histochem Cytochem.. 2000
Upstream stimulatory factor is involved in the regulation of the human calcyclin (S100A6) gene.
Leśniak W, Jezierska A, Kuźnicki J.
Biochim Biophys Acta.. 2000
Regulation of cell specific expression of calcyclin (S100A6) in nerve cells and other tissues.
Leśniak W, Swart GW, Bloemers HP, Kuźnicki J.
Acta Neurobiol Exp (Wars). . 2000
Polish Centenarians Program “PolStu99” – search for longevity promoting factors (in Polish)
Mossakowska M, Puzianowska-Kuznicka M, Barcikowska M, Chiron-Jouan S, Czyzewski K, Derejczyk J, Franceschi C, Gabryelewicz T, Galus K, Grodzicki T, Gross R, Klich-Raczka A, Luczywek E, Passeri G, Pfeffer A, Pruszynski J, Radziszewska E, Sikora E, Sosnowski M, Styczynska M, Wasiak B, Wieczorowska-Tobis K, Zyczkowska J, Kuznicki J
Gerontologia. 2000
Prediction of a common fold for all four subunits of the yeast tRNA splicing endonuclease: implications for the evolution of the EndA/Sen family.
Bujnicki JM, Rychlewski L
FEBS Lett. 2000
Prediction of a novel RNA 2'-O-ribose methyltransferase subfamily encoded by the Escherichia coli YgdE open reading frame and its orthologs
Bujnicki JM, Rychlewski L
Acta Microbiol Pol. 2000
Atomic model of the 5-methylcytosine-specific restriction enzyme McrA reveals an atypical zinc finger and structural similarity to betabetaalphaMe endonucleases
Bujnicki JM, Radlinska M, Rychlewski L
Mol Microbiol. 2000