The scientists from the Laboratory of Protein Structure collaborated with Joe Peters group from Cornell University to study the structure of mechanism of prototypic E. coli Tn7 TnsB. The findings are avaiable in the recent publication Molecular Cell.
A workshop for representatives of Polish DIOSCURI Centers was held in Munich at the headquarters of the Max Planck Society on July 11-12.
Zebrafish, a popular organism for studying embryonic development and modeling human diseases - already has a functional annotation program similar to that in other animal models.
IIMCB researchers from the Laboratory of Protein Structure studied the structures of DNA polymerases AbiK and Abi-P2 that are involved in the defense of bacteria against invading viruses. The structures revealed a very unusual hexameric and trimeric architecture of these enzymes. Based on the set of structures and accompanying biochemical and biophysical analyses, the molecular mechanism of the Abi polymerases was explained.