Title
Rational discovery of therapeutic PAK1 allosteric activators.
Type
Publication
Author
He Y, Bae JSH, Nowak E, Outeiral C, Nissley DA, Tumber A, Berridge G, Salah E, Wang Y, He W, Zhang H, Chen T, Tusk S, Mathea S, Wang YJ, Grassam-Rowe A, Kukura P, Schofield CJ, O'Brien DP, Pierangelini A, Churchill GC, Lanyon-Hogg T, Ke Y, Xu C, Ye T, Watkins H, Ying L, Koschinski A, Solaro RJ, Tan X, Bolla JR, Wang X, Knapp S, Deane CM, Zaccolo M, Nowotny M, Lei M.
Year
2026
Journal
Cell
Volume
Epub ahead of print
DOI
10.1016/j.cell.2026.03.008