Informacje na temat rekrutacji dostępne na BIP

1. 1 PhD student position - Laboratory of Prokaryotic Gene Regulation (NCN/SONATA BIS)

2. 1 PhD student position - Laboratory of Prokaryotic Gene Regulation (NCN/OPUS)

3. 1 PhD student position - Laboratory of Molecular and Cellular Neurobiology (NCN/OPUS)

4. 1 PhD student position - Laboratory of Protein Structure (NCN/OPUS)

5. 1 PhD student position - Laboratory of Cellular Proteostasis (NCN/SONATA BIS)

6. 1 PhD student position - Laboratory of Cellular Proteostasis (NCN/SONATA BIS)

7. 1 PhD student position - Laboratory of RNA Splicing (NCN/SONATA BIS)

Archive:

1. 1 PhD student position - Laboratory of Protein Structure

2. 1 PhD student position - Labolatory of Cellular Genomics

3. 1 PhD student position - Laboratory of Prokaryotic Gene Regulation

4. 2 PhD students positions - Laboratory o Iron Homeostasis

5. 2 PhD students positions - Laboratory of Molecular and Cellular Neurobiology

6. 2 PhD students positions - Laboratory of Prokaryotic Gene Regulation

Informacje na temat rekrutacji dostępne na BIP

Project Title:
Identification of Biomarkers of Metabolic Dysfunction–Associated Steatotic Liver Disease

Funding:
The project is funded under the National Recovery and Resilience Plan (Krajowy Plan Odbudowy i Zwiększania Odporności), Component D – Efficiency, accessibility, and quality of the healthcare system, Investment D3.1.1 – Comprehensive development of research in the field of medical and health sciences, from KPO funds distributed through the Medical Research Agency (Agencja Badań Medycznych) under the call for scientific institutions to conduct application-oriented biomedical research (2024/ABM/03/KPO).

Funding Amount:
PLN 5,244,375.00

Study Description:
The study focuses on identifying biomarkers of metabolic dysfunction–associated steatotic liver disease (MASLD) while accounting for patient metabotypes. MASLD is a complex condition currently diagnosed mainly through imaging techniques and clinical criteria. The metabolic diversity of patients makes it challenging to pinpoint molecular indicators of the disease. Therefore, the project incorporates advanced metabolic and microbiome-based stratification to address patient heterogeneity.

Project Objectives:

• Identification of molecular biomarkers of metabolic dysfunction–associated steatotic liver disease, considering patient metabotypes.

• Understanding the relationship between the presence or risk of MASLD and specific metabolic states.

• Stratification of the patient population based on metabolic status and gut microbiome composition.

• Integration of multi-omics data (metabolomics, metagenomics, metaproteomics) to identify biomarkers specific to defined metabotypes.

Methodology:
Study population: 400 individuals aged 35–65 years, residing in Warsaw.

Study stages:

1. Information meeting and collection of data on lifestyle, diet, medication use, etc.
2. Self-collection of a stool sample by the participant (transport under controlled conditions).
3. Venous blood sampling and liver elastography.
4. Medical consultation including interpretation of test results.

Milestones:
1. Establishing collaboration with enel-med for blood sample collection and result consultations with internal medicine specialists.
2. Establishing collaboration with the Ministry of Interior and Administration Hospital (MSWiA) for liver elastography procedures.
3. Recruitment of study participants.
4. Establishing collaboration with Biogenity and Metabolon.
5. Completion of biological material collection.
6. Shipment of samples to Denmark and the USA for multi-omics analyses.

More information: https://www.zbadaj-sie.pl/

Project Title 

Comprehensive support for international researchers at IIMCB — an essential element of conducting high-quality research
AGREEMENT NO. BPI/WTP/2024/1/00046/U/00001

Tasks and activities to be implemented under the project:

1. Organization of Polish Culture Days

2. Organization of a reporting and integration trip for all employees and doctoral students of IIMCB

3. Staff reinforcement of the support point for foreigners at IIMCB

4. Purchase of necessary IT equipment to furnish the support point for foreigners at IIMCB

5. Signage of the support point for foreigners at MIBMiK

6. Intercultural communication workshops for administrative staff

7. Intercultural team management workshops for managerial staff

8. English language course for administrative staff

9. Specialized training for administrative staff

10. Development of a film presenting the stories of three foreigners who received comprehensive integration support from IIMCB. The film will be shared on the Institute's website, social media, and internal newsletter.

11. Purchase of gadgets for welcome kits and their distribution among new Institute employees

Target Groups

1. Foreigners (over 50 individuals), including employees under employment contracts, doctoral students, and other IIMCB collaborators

2. Polish researchers at various career stages (Master's students, doctoral students, postdocs, researchers, and senior researchers), engineering and technical staff, as well as research and technical staff at IIMCB (approx. 150 individuals)

3. Administrative employees, including those working directly in laboratories as liaisons between science and formalities (approx. 50 individuals)

4. Lab Leaders and Core Facilities Managers (approx. 22 individuals)

Project Goals

Goal 1: Develop the competencies of administrative staff in working with and supporting foreign employees through the organization of specialist and language training 

Goal 2: Develop intercultural communication competencies among administrative and managerial staff through dedicated workshops

Goal 3: Improve the designated area for assisting and supporting foreigners by providing proper signage and purchasing IT equipment 

Goal 4: Expand professional support for foreigners by funding an increase in staff at the Welcome Point 

Goal 5: Promote IIMCB as a professional and foreigner-friendly place for education and scientific research by creating and publishing a film about support provided to three foreign nationals 

Goal 6: Strengthen the sense of engagement and belonging to the group and the institution by organizing integration events and purchasing IIMCB-branded gadgets

Project Outcomes and Results

1. Participation in integration events will allow ~50 foreigners to build closer relationships with Polish employees and other members of the international community, strengthening their sense of belonging to the institution and reducing cultural barriers through better understanding of Polish culture and the work environment. Additionally, the project will enhance international integration within the Institute. Implementation of Goal 6

2. Training of 60 administrative staff members in intercultural communication. As a result, they will gain skills to communicate more effectively with foreigners, taking into account language and cultural differences. Staff will learn to recognize and understand diverse needs and perspectives of foreign nationals, leading to friendlier and more effective relationships. They will also better handle the delivery of clear instructions and resolve foreigner-specific issues. Approximately 20 administrative employees will be funded for language courses, strengthening communication between researchers and administration. Implementation of Goals 1 and 2

3. Management staff (approx. 22 individuals) will gain knowledge and tools to build multicultural teams, improving collaboration and team dynamics. Managers will learn how to identify and effectively manage potential tensions arising from cultural differences, reducing conflicts and improving the work atmosphere. We assume that implementing more inclusive management methods will contribute to a stronger sense of belonging and workplace comfort among foreign staff. Implementation of Goal 2

4. As part of the project, a contact point for foreign employees and doctoral students will be marked, offering support for everyday challenges, making it easier for foreigners to quickly locate a place where they can get help and information. Additionally, 0.5 FTE for foreigner support will be funded. Implementation of Goals 3 and 4

5. The purchase of branded gadgets will strengthen the sense of team belonging, aiding adaptation and reducing stress at the start of employment. Small gifts with the IIMCB logo enhance organizational identity and also boost motivation and job satisfaction. 
   Implementation of Goal 6 

Project Value

PLN 544,408.00

Planned Support Schedule for Project Planned Support Schedule for Project Planned Support Schedule for Project Participants

Recruitment for Administrative Staff

Thapa P, Chikale RV, Szulc NA, Pandrea MT, Sztyler A, Jaggi K, Niklewicz M, Serwa RA, Hoppe T, Pokrzywa W. HSP70 inhibits CHIP E3 ligase activity to maintain germline function in Caenorhabditis elegans. J Biol Chem. 2024 Nov; 300(11):107864. doi: 10.1016/j.jbc.2024.107864
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Rydzanicz M, Kuzniewska B, Magnowska M, Wójtowicz T, Stawikowska A, Hojka A, Borsuk E, Meyza K, Gewartowska O, Gruchota J, Miłek J, Wardaszka P, Chojnicka I, Kondrakiewicz L, Dymkowska D, Puścian A, Knapska E, Dziembowski A, Płoski R, Dziembowska M. Mutation in the mitochondrial chaperone TRAP1 leads to autism with more severe symptoms in males. EMBO Mol Med. 2024 Nov;16(11):2976-3004. doi: 10.1038/s44321-024-00147-6
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https://academic.oup.com/nar/article/53/3/gkae1252/7929375?login=false

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The admissions process is conducted through the Doctoral School website system. The PhD student can apply to this specific project carried out as part of the Warsaw-4-PhD doctoral school via website https://shorturl.at/cJKQY (the application system will be activated from 25^th of July, 2025; deadline for sending application is 8^th August, 2025). For more information, please follow the link https://shorturl.at/mvxOR

1. Reconstructing cardiovascular cell lineage evolution, one cell at a time NCN/OPUS (Laboratory of Zebrafish Developmental Genomics, 1 position)
2. Dynamics of RNA-degrading complexes in bacteria NCN/SONATA BIS (Laboratory of Single-Molecule Biophysics, 1 position)
3. RNA-Protein Interactions in Human Health and Disease NCN/DIOSUCRI (Laboratory of RNA-Protein Interactions - Dioscuri Centre, 1 position)
4. Mechanistic and structural studies of adenoviral DNA replication NCN/OPUS (Laboratory of Protein Structure, 1 position)