Publications

All publications

2017

Pasricha SR, Lim PJ, Duarte TL, Casu C, Oosterhuis D, Mleczko-Sanecka K, Suciu M, Da Silva AR, Al-Hourani K, Arezes J, McHugh K, Gooding S, Frost JN, Wray K, Santos A, Porto G, Repapi E, Gray N, Draper SJ, Ashley N, Soilleux E, Olinga P, Muckenthaler MU, Hughes JR, Rivella S, Milne TA, Armitage AE, Drakesmith H.

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

Nat Commun

Piven OO, Winata CL

The canonical way to make a heart: β-catenin and plakoglobin in heart development and remodeling

Experimental Biology and Medicine

Charbonnel C, Niazi AK, Elvira-Matelot E, Nowak E, Zytnicki M, de Bures A, Jobet E, Opsomer A, Shamandi N, Nowotny M, Carapito C, Reichheld J-P, Vaucheret H, Saez-Vasquez J.

The siRNA suppressor RTL1 is redox-regulated through glutathionylation of a conserved cysteine in the double-stranded-RNA-binding domain.

Nucleic Acids Res.

Rydzik AM, Warminski M, Sikorski PJ, Baranowski MR, Walczak S, Kowalska J, Zuberek J, Lukaszewicz M, Nowak E, W Claridge TD, Darzynkiewicz E, Nowotny M, Jemielity J.

mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.

Nucleic Acids Res.

Rydzik AM, Warminski M, Sikorski PJ, Baranowski MR, Walczak S, Kowalska J, Zuberek J, Lukaszewicz M, Nowak E, W Claridge TD, Darzynkiewicz E, Nowotny M, Jemielity J.

mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.

Nucleic Acids Res.

Szybinska A, Lesniak W

P53 Dysfunction in Neurodegenerative Diseases – The Cause or Effect of Pathological Changes?

Aging Dis.

Łabuz-Roszak B, Machowska-Majchrzak A, Skrzypek M, Mossakowska M, Chudek J, Więcek A, Wawrzyńczyk M, Łącka-Gaździk B, Pierzchała K

Antiplatelet and anticoagulant therapy in elderly people with type 2 diabetes mellitus in Poland (based on the PolSenior Study)

Arch Med Sci

Korzh V

Development of brain ventricular system

Cell Mol Life Sci

Shen H, Shin EM, Lee S, Mathavan S, Koh H, Osato M, Choi H, Tergaonkar V, Korzh V

Ikk2 regulates cytokinesis during vertebrate development

Sci Rep

Figiel M, Nowotny M

Chapter Six - Structural Studies of RNases H2 as an Example of Crystal Structure Determination of Protein–Nucleic Acid Complexes

Methods in Enzymology

Figiel M, Krepl M, Poznanski J, Golab A, Šponer J, Nowotny M

Coordination between the polymerase and RNase H activity of HIV-1 reverse transcriptase

Nucleic Acids Res.

Pokrzywa W, Lorenz R, Hoppe T

Chaperone-directed ubiquitylation maintains proteostasis at the expense of longevity.

Worm (in press)

Łabuz-Roszak B, Skrzypek M, Machowska-Majchrzak A, Mossakowska M, Chudek J, Więcek A, Pierzchała K, Łącka-Gaździk B, Grodzicki T

Pharmacological stroke prevention in the elderly with atrial fibrillation in Poland - Results of PolSenior study

Neurol Neurochir Pol

Klimczak M, Czerwińska P, Mazurek S, Sozańska B, Biecek P, Mackiewicz A, Wiznerowicz M

TRIM28 epigenetic corepressor is indispensable for stable induced pluripotent stem cell formation

Stem Cell Research

Mleczko-Sanecka K, da Silva AR, Call D, Neves J, Schmeer N, Damm G, Seehofer D, Muckenthaler MU

Imatinib and spironolactone suppress hepcidin expression

Haematologica

Gozdz A, Nikolaienko O, Urbanska M, Cymerman IA, Sitkiewicz E, Blazejczyk M, Dadlez M, Bramham CR, Jaworski J

GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation

Front Mol Neurosci

Kevei É, Pokrzywa W, Hoppe T

Repair or Destruction: An Intimate Liaison Between Ubiquitin Ligases and Molecular Chaperones in Proteostasis

FEBS Lett. doi:10.1002/1873-3468.12750.

Koh CH, Wu J, Chung YY, Liu Z, Zhang RR, Chong K, Korzh V, Ting S, Oh S, Shim W, Tian HY, Wei H

Identification of a Na+/K+-ATPase inhibition-independent proarrhythmic ionic mechanisms of cardiac glycosides

Sci Rep.

Tan SY, Teh C, Ang CY, Li M, Li P, Korzh V, Zhao Y

Responsive mesoporous silica nanoparticles for sensing of hydrogen peroxide and simultaneous treatment toward heart failure

Nanoscale

Owczarz M, Budzinska M, Domaszewska-Szostek A, Borkowska J, Polosak J, Gewartowska M, Slusarczyk P, Puzianowska-Kuznicka M

miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans

Experimental Biology and Medicine

Tracz-Gaszewska Z, Klimczak M, Biecek P, Herok M, Kosinski M, Olszewski MB, Czerwińska P, Wiech M, Wiznerowicz M, Zylicz A, Zylicz M, Wawrzynow B

Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation

Oncotarget

Pruszko M, Milano E, Forcato M, Donzelli S, Ganci F, Di Agostino S, De Panfilis S, Fazi F, Bates DO, Bicciato S, Zylicz M, Zylicz A, Blandino G, Fontemaggi G

The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1

EMBO Rep

Budzko L, Jackowiak P, Kamel K, Sarzynska J, Bujnicki JM, Figlerowicz M

Mutations in human AID differentially affect its ability to deaminate cytidine and 5-methylcytidine in ssDNA substrates in vitro

Sci Rep

Karlowicz A, Wegrzyn K, Gross M, Kaczynska D, Ropelewska M, Siemiątkowska M, Bujnicki JM, Konieczny I

Defining the crucial domain and amino acid residues in bacterial Lon protease for DNA binding and processing of DNA-interacting substrates

J Biol Chem

Miao Z, Adamiak RW, Antczak M, Batey RT, Becka A, Biesiada M, Boniecki MJ, Bujnicki JM, Chen S, Cheng CY, Chou F, Ferré-D'Amaré AR, Das R, Dawson WK, Ding F, Dokholyan NV, Dunin-Horkawicz S, Geniesse C, Kappel K, Kladwang W, Krokhotin A, Lach GE, Major F, Mann TH, Magnus M, Pachulska-Wieczorek K, Patel DJ, Piccirilli JA, Popenda M, Purzycka KJ, Ren A, Rice GM, Santalucia J Jr, Sarzynska J, Szachniuk M, Tandon A, Trausch JJ, Tian S, Wang J, Weeks KM, Williams B II, Xiao Y, Xu X, Zhang D, Zok T, Westhof E

RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme

RNA

Urbanska AS, Janusz-Kaminska A, Switon K, Hawthorne AL, Perycz M, Urbanska M, Bassell GJ, Jaworski J

ZBP1 phosphorylation at serine 181 regulates its dendritic transport and the development of dendritic trees of hippocampal neurons

Sci Rep

de Hoz L, Gierej D, Lioudyno V, Jaworski J, Blazejczyk M, Cruces-Solís H, Beroun A, Lebitko T, Nikolaev T, Knapska E, Nelken I, Kaczmarek L

Blocking c-Fos Expression Reveals the Role of Auditory Cortex Plasticity in Sound Frequency Discrimination Learning

Cereb Cortex

Kononenko NL, Claßen GA, Kuijpers M, Puchkov D, Maritzen T, Tempes A, Malik AR, Skalecka A, Bera S, Jaworski J, Haucke V

Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration

Nat Commun

Chacinska A.

Cell biology: Sort and destroy

Nature

Bragoszewski P, Turek M, Chacinska A.

Control of mitochondrial biogenesis and function by the ubiquitin-proteasome system

Open Biol

Koscielny A, Malik AR, Liszewska E, Zmorzynska J, Tempes A, Tarkowski B, Jaworski J

Adaptor Complex 2 Controls Dendrite Morphology via mTOR-Dependent Expression of GluA2

Mol Neurobiol

Aksoy I, Utami KH, Winata CL, Hillmer AM, Rouam SL, Briault S, Davila S, Stanton LW, Cacheux V

Personalized genome sequencing coupled with iPSC technology identifies GTDC1 as a gene involved in neurodevelopmental disorders

Hum Mol Genet

Kawalec P, Stawowczyk E, Mossakowska M, Pilc A

Disease activity, quality of life, and indirect costs of ulcerative colitis in Poland

Prz Gastroenterol

Nagaraj S, Laskowska-Kaszub K, Dębski KJ, Wojsiat J, Dąbrowski M, Gabryelewicz T, Kuźnicki J, Wojda U

Profile of 6 microRNA in blood plasma distinguish early stage Alzheimer's disease patients from non-demented subjects

Oncotarget

Brendel M, Kleinberger G, Probst F, Jaworska A, Overhoff F, Blume T, Albert NL, Carlsen J, Lindner S, Gildehaus FJ, Ozmen L, Suárez-Calvet M, Bartenstein P, Baumann K, Ewers M, Herms J, Haass C, Rominger A

Increase of TREM2 during Aging of an Alzheimer’s Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis

Front. Aging Neurosci.

Majerczyk M, Choręza P, Bożentowicz-Wikarek M, Brzozowska A, Arabzada H, Owczarek A, Mossakowska M, Grodzicki T, Zdrojewski T, Więcek A, Olszanecka-Glinianowicz M, Chudek J

Increased plasma RBP4 concentration in older hypertensives is related to the decreased kidney function and the number of antihypertensive drugs-results from the PolSenior substudy

J Am Soc Hypertens

The RNAcentral Consortium (Petrov AI et al within Bujnicki JM)

RNAcentral: a comprehensive database of non-coding RNA sequences

Nucleic Acids Res

NCD Risk Factor Collaboration (Zhou B, Bentham J, ......... M. Mossakowska and P. Ślusarczyk)

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

Lancet

Jastrzębski K, Zdżalik-Bielecka D, Mamińska A, Kalaidzidis Y, Hellberg C, Miaczynska M

Multiple routes of endocytic internalization of PDGFRβ contribute to PDGF-induced STAT3 signaling

J Cell Sci.

Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J

Molecular neurobiology of mTOR

Neuroscience

Bochtler M, Kolano A, Xu G-L

DNA demethylation pathways: Additional players and regulators

Bioessays

Soman S, Keatinge M, Moein M, DaCosta M, Mortiboys H, Skupin A, Sugunan S, Bazala M, Kuznicki J, Bandmann O.

Inhibition of the mitochondrial calcium uniporter (MCU) rescues dopaminergic neurons in pink1-/- zebrafish.

Eur J Neurosci.

Misztal K, Brozko N, Nagalski A, Szewczyk LM, Królak M, Brzozowska K, Kuznicki J, Wisniewska MB

TCF7L2 mediates the cellular and behavioral response to chronic lithium treatment in animal models

Neuropharmacology

Gross B, Pawlak M, Lefebvre P, Staels B.

PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD.

Nat Rev Endocrinol TEST

Magnus MM, Boniecki MJ, Dawson WK, Bujnicki JM

SimRNAweb: a web server for RNA 3D structure modeling with optional restraints

Nucleic Acids Res

Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M

ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors

Sci Signal

2016

Holko P, Kawalec P, Mossakowska M, Pilc A

Health-Related Quality of Life Impairment and Indirect Cost of Crohn's Disease: A Self-Report Study in Poland

PLoS One

Dawson WK, Maciejczyk M, Jankowska EJ, Bujnicki JM

Coarse-grained modeling of RNA 3D structure

Methods

Machnicka MA, Dunin-Horkawicz S, de Crécy-Lagard V, Bujnicki JM

tRNAmodpred: A computational method for predicting posttranscriptional modifications in tRNAs

Methods

Urulangodi M, Dhanaraju R, Gupta K, Roy RP, Bujnicki JM, Rao DN

Asymmetric DNA methylation by dimeric EcoP15I DNA methyltransferase

Biochimie

Pawlowski M, Kozlowski L, Kloczkowski A

MQAPsingle: A quasi single-model approach for estimation of the quality of individual protein structure models

Proteins

The RNAcentral Consortium (Petrov AI et al within Bujnicki JM)

RNAcentral: a comprehensive database of non-coding RNA sequences

Nucleic Acids Res

Iskierko Z, Sharma PS, Prochowicz D, Fronc K, D'Souza F, Toczydłowska D, Stefaniak F, Noworyta K

Molecularly Imprinted Polymer (MIP) Film with Improved Surface Area Developed by Using Metal-Organic Framework (MOF) for Sensitive Lipocalin (NGAL) Determination.

ACS Appl Mater Interfaces.

Glow D, Kurkowska M, Czarnecka J, Szczepaniak K, Pianka D, Kappert V, Bujnicki JM, Skowronek KJ

Identification of protein structural elements responsible for the diversity of sequence preferences among Mini-III RNases.

Sci Rep.

Kalisiak K, Kuliński TM, Tomecki R, Cysewski D, Pietras Z, Chlebowski A, Kowalska K, Dziembowski A

A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans

Nucleic Acids Res

Krzyminska-Siemaszko R, Chudek J, Suwalska A, Lewandowicz M, Mossakowska M, Kroll-Balcerzak R, Wizner B, Tobis S, Mehr K, Wieczorowska-Tobis K

Health status correlates of malnutrition in the polish elderly population - Results of the Polsenior Study

Eur Rev Med Pharmacol Sci

Budzinska M, Owczarz M, Pawlik-Pachucka E, Roszkowska-Gancarz M , Slusarczyk P, Puzianowska-Kuznicka M

miR-96, miR-145 and miR-9 expression increases, and IGF-1R and FOXO1 expression decreases in peripheral blood mononuclear cells of aging humans

BMC Geriatr

NCD Risk Factor Collaboration (Zhou B, Bentham J, ......... M. Mossakowska and P. Ślusarczyk)

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

Lancet

NCD Risk Factor Collaboration (793 Collaborators within M. Mossakowska and P. Ślusarczyk)

A century of trends in adult human height

Elife


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Grulich M, Brezovský J, Štěpánek V, Palyzová A, Marešová H, Zahradník J, Kyslíková E, Kyslík P

In-silico driven engineering of enantioselectivity of a penicillin G acylase towards active pharmaceutical ingredients

J Mol Catal B-Enzym

Patel T, Chojnowski G, Astha, Koul A, McKenna S, Bujnicki JM

Structural studies of RNA-protein complexes: A hybrid approach involving hydrodynamics, scattering and computational methods

Methods

Tudek B, Zdżalik-Bielecka D, Tudek A, Kosicki K, Fabisiewicz A, Speina E

Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes

Free Radic Biol Med

Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J

Molecular neurobiology of mTOR

Neuroscience

Bochtler M, Kolano A, Xu G-L

DNA demethylation pathways: Additional players and regulators

Bioessays

Jasińska M, Miłek J, Cymerman IA, Łęski S, Kaczmarek L, Dziembowska M

miR-132 Regulates Dendritic Spine Structure by Direct Targeting of Matrix Metalloproteinase 9 mRNA

Mol Neurobiol.

Szychowska M, Siwek W, Pawolski D, Kazrani AA, Pyrc K, Bochtler M

Type III CRISPR complexes from Thermus thermophilus

Acta Biochim Pol

Wasilewski M, Chojnacka K, Chacinska A

Protein trafficking at the crossroads to mitochondria

Biochim Biophys Acta

Wasilewski M, Chojnacka K, Chacinska A

Białka mitochondrialne – import, eksport, degradacja

Postępy Biochemii

Soman S, Keatinge M, Moein M, DaCosta M, Mortiboys H, Skupin A, Sugunan S, Bazala M, Kuznicki J, Bandmann O

Inhibition of the mitochondrial calcium uniporter (MCU) rescues dopaminergic neurons in pink1-/- zebrafish

Eur J Neurosci.

Stracy M, Jaciuk M, Uphoff S, Kapanidis AN, Nowotny M, Sherratt DJ, Zawadzki P

Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli

Nat Commun.

Misztal K, Brozko N, Nagalski A, Szewczyk LM, Królak M, Brzozowska K, Kuznicki J, Wisniewska MB

TCF7L2 mediates the cellular and behavioral response to chronic lithium treatment in animal models

Neuropharmacology

Piotrowicz K, Pac A, Skalska AB, Chudek J, Klich-Rączka A, Szybalska A, Michel JP, Grodzicki T

Clustering of geriatric deficits emerges to be an essential feature of ageing - results of a cross-sectional study in Poland

Aging (Albany NY)

Korzeniowski P, Wiweger M

Pseudoloma neurophilia (Microsporidia) – poważne zagrożenie dla hodowli laboratoryjnej danio pręgowanego (Danio rerio, Hamilton 1822)

Życie Weterynaryjne

Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J

Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches

IUBMB Life

Gruszczynska-Biegala J, Sladowska M, Kuznicki J

AMPA Receptors Are Involved in Store-Operated Calcium Entry and Interact with STIM Proteins in Rat Primary Cortical Neurons

Frontiers in Cellular Neuroscience

Nadrowski P, Chudek J, Skrzypek M, Puzianowska-Kuźnicka M, Mossakowska M, Więcek A, Zdrojewski T, Grodzicki T, Kozakiewicz K

Associations between cardiovascular disease risk factors and IL-6 and hsCRP levels in the elderly

Exp Gerontol

Callegari S, Richter F, Chojnacka K, Jans DC, Lorenzi I, Pacheu-Grau D, Jakobs S, Lenz C, Urlaub H, Dudek J, Chacinska A, Rehling P

TIM29 is a subunit of the human carrier translocase required for protein transport

FEBS Lett

Czeredys M, Maciag F, Methner A, Kuznicki J

Tetrahydrocarbazoles decrease elevated SOCE in medium spiny neurons from transgenic YAC128 mice, a model of Huntington's disease

Biochem Biophys Res Commun

Mikula M, Skrzypczak M, Goryca K, Paczkowska K, Ledwon JK, Statkiewicz M, Kulecka M, Grzelak M, Dabrowska M, Kuklinska U, Karczmarski J, Rumienczyk I, Jastrzebski K, Miaczynska M, Ginalski K, Bomsztyk K, Ostrowski J.

Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.

Nucleic Acids Res

Wegierski T, Gazda K, Kuznicki J

Microscopic analysis of Orai-mediated store-operated calcium entry in cells with experimentally altered levels of amyloid precursor protein

Biochem Biophys Res Commun

Van Laer B, Roovers M, Wauters L, Kasprzak JM, Dyzma M, Deyaert E, Singh R, Feller A, Bujnicki JM, Droogmans L, Versées W

Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue

Nucleic Acids Res

Dawson WK, Bujnicki JM

Computational modeling of RNA 3D structures and interactions

Curr Opin Struct Biol

Boniecki MJ, Lach G, Dawson WK, Tomala K, Lukasz P, Soltysinski T, Rother KM, Bujnicki JM

SimRNA: a coarse-grained method for RNA folding simulations and 3D structure prediction

Nucleic Acids Res

Ukleja M, Cuellar J, Siwaszek A, Kasprzak JM, Czarnocki-Cieciura M, Bujnicki JM, Dziembowski A, Valpuesta J

The architecture of the Schizosaccharomyces pombe CCR4-NOT complex

Nature Commun

Matelska D, Kurkowska M, Purta E, Bujnicki JM, Dunin-Horkawicz S

Loss of conserved non-coding RNAs in genomes of bacterial endosymbionts

Genome Biol Evol

Yahara K, Furuta Y, Morimoto S, Kikutake C, Komukai S, Matelska D, Dunin-Horkawicz S, Bujnicki JM, Uchiyama I, Kobayashi I

Genome-wide survey of codons under diversifying selection in a highly recombining bacterial species, Helicobacter pylori

DNA Res

Bochtler M., Piasecka A

Haloferax volcanii UbaA, catalytic engine for sampylation and sulfur transfer

FEBS J

Skałecka A, Liszewska E, Bilinski R, Gkogkas C, Khoutorsky A, Malik AR, Sonenberg N, Jaworski J

mTOR kinase is needed for the development and stabilization of dendritic arbors in newly born olfactory bulb neurons

Dev Neurobiol

Szewczyk LM, Brozko N, Nagalski A, Rӧckle I, Werneburg S, Hildebrandt H, Wisniewska MB, Kuznicki J free access

ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons

Glia

Cendrowski J, Mamińska A, Miaczynska M

Endocytic regulation of cytokine receptor signaling

Cytokine Growth Factor Rev

van Scheppingen J, Iyer AM, Prabowo AS, Mühlebner A, Anink JJ, Scholl T, Feucht M, Jansen FE, Spliet WG, Krsek P, Zamecnik J, Buccoliero AM, Giordano F, Genitori L, Kotulska K, Jozwiak S, Jaworski J, Liszewska E, van Vliet EA, Aronica E

Expression of microRNAs miR21, miR146a, and miR155 in tuberous sclerosis complex cortical tubers and their regulation in human astrocytes and SEGA-derived cell cultures

Glia

Jagielska E, Chojnacka O, Sabala I

LytM Fusion with SH3b-Like Domain Expands Its Activity to Physiological Conditions

Microb Drug Resist

Turakhiya U, von der Malsburg K, Gold VA, Guiard B, Chacinska A, van der Laan M, Ieva R

Protein Import by the Mitochondrial Presequence Translocase in the Absence of a Membrane Potential

J Mol Biol

Di Cesare M, … Mossakowska M, … Slusarczyk P, … - 756 collaborators (NCD-RisC)

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

Lancet

Zhou B, … Mossakowska M, … Slusarczyk P, … - 513 collaborators (NCD-RisC)

Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants

Lancet

Prajsner A, Chudek J, Szybalska A, Piotrowicz K, Zejda J, Więcek A

Socioeconomic determinants of prostate-specific antigen testing and estimation of the prevalence of undiagnosed prostate cancer in an elderly Polish population based on the PolSenior study

Arch Med Sci

Kozak-Szkopek E, Broczek K, Slusarczyk P, Wieczorowska-Tobis K, Klich-Raczka A, Szybalska A, Mossakowska M

Prevalence of chronic pain in the elderly Polish population – results of the PolSenior study

Arch Med Sci

Wrobel L, Sokol AM, Chojnacka M, Chacinska A

The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly

Sci Rep

Puzianowska-Kuznicka M, Owczarz M, Wieczorowska-Tobis K, Nadrowski P, Chudek J, Slusarczyk P, Skalska A, Jonas M, Franek E, Mossakowska M

Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study

Immunity & Ageing

Mierzejewska K, Bochtler M, Czapinska H

On the role of steric clashes in methylation control of restriction endonuclease activity

Nucleic Acids Res

Haniewicz P, Floris D, Farci D, Kirkpatrick J, Loi MC, Büchel C, Bochtler M, Piano D

Isolation of Plant Photosystem II Complexes by Fractional Solubilization

Front Plant Sci

Topf U, Wrobel L, Chacinska A

Chatty Mitochondria: Keeping Balance in Cellular Protein Homeostasis

Trends Cell Biol

Hamann L, Bustami J, Iakoubov L, Szwed M, Mossakowska M, Schumann RR, Puzianowska-Kuznicka M

TLR-6 SNP P249S is associated with healthy aging in nonsmoking Eastern European Caucasians - A cohort study

Immun Ageing

Kevenaar JT, Bianchi S, van Spronsen M, Olieric N, Lipka J,Frias CP, Mikhaylova M, Harterink M, Keijzer N, Wulf PS, Hilbert M, Kapitein LC, de Graaff E, Ahkmanova A, Steinmetz MO, Hoogenraad CC

Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity

Curr Biol

Blazejczyk M, Macias M, Korostynski M, Firkowska M, Piechota M, Skalecka A, Tempes A, Koscielny A, Urbanska M, Przewlocki R, Jaworski J

Kainic Acid Induces mTORC1-Dependent Expression of Elmo1 in Hippocampal Neurons

Mol Neurobiol

Song J, Mu Y, Li C, Bergh A, Miaczynska M, Heldin CH, Landström M

APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain

Oncotarget

Tan H, Onichtchouk D, Winata C

DANIO-CODE: Toward an Encyclopedia of DNA Elements in Zebrafish

Zebrafish

Nowotny M, Gaur V

Structure and mechanism of nucleases regulated by SLX4

Curr Opin Struct Biol

Zajac-Gawlak I, Pospiech D, Kroemeke A, Mossakowska M, Gába A, Pelclová J, Pridalová M, Kłapcinska B

Physical activity, body composition and general health status of physically active students of the University of the Third Age (U3A)

Archives of Gerontology and Geriatrics

Lipka J, Kapitein LC, Jaworski J, Hoogenraad CC

Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites

EMBO J

Kondratiuk I, Łęski S, Urbańska M, Biecek P, Devijver H, Lechat B, Van Leuven F, Kaczmarek L, Jaworski T

GSK-3β and MMP-9 Cooperate in the Control of Dendritic Spine Morphology

Mol Neurobiol

Wasiak I, Kulikowska A, Janczewska M, Michalak M, Cymerman IA, Nagalski A, Kallinger P, Szymanski WW, Ciach T

Dextran Nanoparticle Synthesis and Properties

PLoS One

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Mossakowska M , Broczek K, Wieczorowska-Tobis K, Klich-Raczka A, Jonas M, Pawlik-Pachucka E, Safranow K, Kuznicki J , Puzianowska-Kuznicka M

Cognitive Performance and Functional Status Are the Major Factors Predicting Survival of Centenarians in Poland

J Gerontol A Biol Sci Med Sci

Geremek M, Ziętkiewicz E, Bruinenberg M, Franke L, Pogorzelski A, Wijmenga C, Witt M

Ciliary genes are down-regulated in bronchial tissue of primary ciliary dyskinesia patients

PLoS One

Smietanski M, Werner M, Purta E, Kaminska KH, Stepinski J, Darzynkiewicz E, Nowotny M, Bujnicki JM

Structural analysis of human 2′-O-ribose methyltransferases involved in mRNA cap structure formation

Nat Commun

Chojnowski G, Walen T, Bujnicki JM

RNA Bricks - a database of RNA 3D motifs and their interactions

Nucleic Acids Res.

Dzananovic E, Patel TR, Chojnowski G, Boniecki MJ, Deo S, McEleney K, Harding SE, Bujnicki JM, McKenna SA

Solution conformation of Adenovirus Virus Associated RNA-I and its interaction with PKR

J Struct Biol

Plotka M, Kaczorowska AK, Stefanska A, Morzywolek A, Fridjonsson OH, Dunin-Horkawicz S, Kozlowski L, Hreggvidsson GO, Kristjansson JK, Dabrowski S, Bujnicki JM, Kaczorowski T

Novel Highly Thermostable Endolysin from Thermus scotoductus MAT2119 Bacteriophage Ph2119 with Amino Acid Sequence Similarity to Eukaryotic Peptidoglycan Recognition Proteins

Appl Environ Microbiol

Tuszynska I, Matelska D, Magnus M, Chojnowski G, Kasprzak JM, Kozlowski LP, Dunin-Horkawicz S, Bujnicki JM

Computational modeling of protein-RNA complex structures

Methods

Jaremko M, Jaremko L, Nowakowski M, Wojciechowski M, Szczepanowski RH, Panecka R, Zhukov I, Bochtler M, Ejchart A

NMR structural studies of the first catalytic half-domain of ubiquitin activating enzyme

J Struct Biol

Skupien A, Konopka A, Trzaskoma P, Labus J, Gorlewicz A, Swiech L, Babraj M, Dolezyczek H, Figiel I, Ponimaskin E, Wlodarczyk J, Jaworski J, Wilczynski GM, Dzwonek J

CD44 regulates dendrite morphogenesis through Src tyrosine kinase-dependent positioning of the Golgi

J Cell Sci

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Madej D, Borowska K, Bylinowska J, Szybalska A, Pietruszka B

Dietary intakes of iron and zinc assessed in a selected group of the elderly: are they adequate

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Biologia w szkole

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Postepy Biochem

Wegierski T

Mikroskopowe metody rejestracji wewnątrzkomórkowych odpowiedzi wapniowych

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Paluch EK, Raz E

The role and regulation of blebs in cell migration

Curr Opin Cell Biol

Xu C, Liu R, Mehta AK, Guerrero-Ferreira RC, Wright ER, Dunin-Horkawicz S, Morris K, Serpell LC, Zuo X, Wall JS, Conticello VP

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Biro M, Romeo Y, Kroschwald S, Bovellan M, Boden A, Tcherkezian J, Roux PP, Charras G, Paluch EK

Cell cortex composition and homeostasis resolved by integrating proteomics and quantitative imaging

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Isolation of monomeric photosystem II that retains the subunit PsbS

Photosynth Res

Philips A, Milanowska K, Lach G, Bujnicki JM

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Czeredys M, Samluk L, Michalec K, Tułodziecka K, Skowronek K, Nałęcz KA

Caveolin-1 - a novel interacting partner of organic cation/carnitine transporter (octn2): effect of protein kinase C on this interaction in rat astrocytes.

PLoS One

Gutmajster E, Witecka J, Wyskida M, Koscinska-Marczewska J, Szwed M, Owczarz M, Mossakowska M, Milewicz A, Puzianowska-Kuznicka M, Zejda J, Wiecek A, Chudek J, Sieron A.L

Telomere Length in Elderly Caucasians Weakly Correlates with Blood Cell Counts

The Scientific World Journal

Honarnejad K, Daschner A, Giese A, Zall A, Schmidt B, Szybinska A, Kuznicki J, Herms J

Development and Implementation of a High-Throughput Compound Screening Assay for Targeting Disrupted ER Calcium Homeostasis in Alzheimer's Disease

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Czeredys M, Gruszczynska-Biegala J, Schacht T, Methner A, Kuznicki J

Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington’s disease

Front. Mol. Neurosci

Lipka J, Kuijpers M,Jaworski J, Hoogenraad CC

Mutations in cytoplasmic dynein and its regulators cause malformations of cortical development and neurodegenerative diseases

Biochem Soc Trans

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FRET-Based Calcium Imaging: A Tool for High-Throughput/Content Phenotypic Drug Screening in Alzheimer Disease

J Biomol Screen

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The fragile x mental retardation protein regulates matrix metalloproteinase 9 mRNA at synapses

J Neurosci

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A Common Copy Number Variation (CNV) Polymorphism in the CNTNAP4 Gene: Association with Aging in Females

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Native STIM2 and ORAI1 proteins form a calcium-sensitive and thapsigargin-insensitive complex in cortical neurons

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Bedzhov I, Alotaibi H, Basilicata MF, Ahlborn K,Liszewska E, Brabletz T, Stemmler MP

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Stem Cell Res

Matelska D, Purta E, Panek S, Boniecki MJ, Bujnicki JM, Dunin-Horkawicz S

S6:S18 ribosomal protein complex interacts with a structural motif present in its own mRNA

RNA

Dudzik J, Chang WC, Kannan AM, Filipek S, Viswanathan S, Li P, Renugopalakrishnan V, Audette GF

Cross-linked glucose oxidase clusters for biofuel cell anode catalysts

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Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain

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Eur Biophys J

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Crochemore M, Iliopoulos C.S, Kociumaka T, Kubica M, Pachocki J, Radoszewski J, Rytter W,Tyczyński W, Waleń T

A note on efficient computation of all Abelian periods in a string

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Towards Improved Quality of GPCR Models by Usage of Multiple Templates and Profile-Profile Comparison

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Wojda U, Kuznicki J

Alzheimer's disease modeling: ups, downs, and perspectives for human induced pluripotent stem cells

J Alzheimers Dis

Maître JL, Berthoumieux H, Gabriel Krens SF, Salbreux G, Jülicher F, Paluch E, Heisenberg CP

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Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation

Cell

Varabyova A, Topf U, Kwiatkowska P, Wrobel L, Kaus-Drobek M, Chacinska A

Mia40 and MINOS act in parallel with Ccs1 in the biogenesis of mitochondrial Sod1

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Pawlowski M, Bogdanowicz A, Bujnicki JM

QA-RecombineIt: a server for quality assessment and recombination of protein models

Nucleic Acids Res

Lukasiak P, Antczak M, Ratajczak T, Bujnicki JM, Szachniuk M, Adamiak RW, Popenda M, Blazewicz J

RNAlyzer--novel approach for quality analysis of RNA structural models

Nucleic Acids Res

Bujnicki JM, Tiuryn J

Bioinformatics and computational biology in Poland

PLoS Comput Biol

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CompaRNA: a server for continuous benchmarking of automated methods for RNA secondary structure prediction

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Nadrowski P, Chudek J, Grodzicki T, Mossakowska M, Skrzypek M, Wiecek A, Zdrojewski T, Kozakiewicz K

Plasma level of N-terminal pro brain natriuretic peptide (NT-proBNP) in elderly population in Poland - the PolSenior Study

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Golanska E, Sieruta M, Corder E, Gresner SM, Pfeffer A, Chodakowska-Zebrowska M, Sobow TM, Klich I, Mossakowska M, Szybinska A, Barcikowska M, Liberski PP

The prion protein M129V polymorphism: Longevity and cognitive impairment among Polish centenarians

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Macias M, Blazejczyk M, Kazmierska P, Caban B, Skalecka A, Tarkowski B, Rodo A, Konopacki J, Jaworski J

Spatiotemporal Characterization of mTOR Kinase Activity Following Kainic Acid Induced Status Epilepticus and Analysis of Rat Brain Response to Chronic Rapamycin Treatment

PLoS One

Kapitein LC, van Bergeijk P, Lipka J, Keijzer N, Wulf PS, Katrukha EA, Akhmanova A, Hoogenraad CC

Myosin-V Opposes Microtubule-Based Cargo Transport and Drives Directional Motility on Cortical Actin

Curr Biol

Sadowski L, Jastrzębski K, Kalaidzidis Y, Heldin CH, Hellberg C, Miaczynska M

Dynamin Inhibitors Impair Endocytosis and Mitogenic Signaling of PDGF

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The ubiquitin-proteasome system regulates mitochondrial intermembrane space proteins

Mol Cell Biol

Kuzniewska B, Rejmak E, Malik AR, Jaworski J, Kaczmarek L, Kalita K

Brain-derived neurotrophic factor induces matrix metalloproteinase-9 expression in neurons via serum response factor/c-Fos pathway

Mol Cell Biol

van Spronsen M, Mikhaylova M, Lipka J, Schlager MA, van den Heuvel DJ, Kuijpers M, Wulf PS, Keijzer N, Demmers J, Kapitein LC, Jaarsma D, Gerritsen HC, Akhmanova A, Hoogenraad CC

TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites

Neuron

Jaworska A, Dzbek J, Styczynska M, Kuznicki J

Analysis of calcium homeostasis in fresh lymphocytes from patients with sporadic Alzheimer's disease or mild cognitive impairment

Biochim Biophys Acta

Bik W, Baranowska-Bik A, Wolinska-Witort E, Kalisz M, Broczek K, Mossakowska M, Baranowska B

Assessment of adiponectin and its isoforms in Polish centenarians

Exp Gerontol

Golanska E, Sieruta M, Gresner SM, Pfeffer A, Chodakowska-Zebrowska M, Sobow TM, Klich I, Mossakowska M, Szybinska A, Barcikowska M, Liberski PP

APBB2 genetic polymorphisms are associated with severe cognitive impairment in centenarians

Exp Gerontol

Wisniewska MB

Physiological Role of β-Catenin/TCF Signaling in Neurons of the Adult Brain

Neurochem Res

Nowak E, Potrzebowski W, Konarev PV, Rausch JW, Bona MK, Svergun DI, Bujnicki JM, Le Grice SF, Nowotny M

Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid

Nucleic Acids Res

Malik AR, Urbanska M, Gozdz A, Swiech LJ, Nagalski A, Perycz M, Blazejczyk M, Jaworski J

CYR61, a matricellular protein, is needed for dendritic arborization of hippocampal neurons

J Biol Chem

Wrobel L, Trojanowska A, Sztolsztener ME, Chacinska A

Mitochondrial protein import: Mia40 facilitates Tim22 translocation into the inner membrane of mitochondria

Mol Biol Cell

Varabyova A, Stojanovski D, Chacinska A

Mitochondrial protein homeostasis

IUBMB Life

Kapustian LL, Vigontina OA, Rozhko OT, Ryabenko DV, Michowski W, Lesniak W, Filipek A, Kroupskaya IV, Sidorik LL

Hsp90 and its co-chaperone, Sgt1, as autoantigens in dilated cardiomyopathy

Heart Vessels

Roszkowska-Gancarz M, Bartoszewicz Z, Polosak J, Kurylowicz A, Jonas M, Mossakowska M, Franek E, Puzianowska-Kuźnicka M

Total and high molecular weight adiponectin and level-modifying polymorphisms of ADIPOQ in centenarians

Endokrynologia Polska

Malik AR, Urbanska M, Macias M, Skalecka A, Jaworski J

Beyond control of protein translation: What we have learned about the non-canonical regulation and function of mammalian target of rapamycin (mTOR)

Biochim Biophys Acta

Esteras N, Alquézar C, Bermejo-Pareja F, Bialopiotrowicz E, Wojda U, Martín-Requero A

Downregulation of extracellular signal-regulated kinase 1/2 activity by calmodulin KII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer's disease patients

Neurobiol Aging

Milanowska K, Mikolajczak K, Lukasik A, Skorupski M, Balcer Z, Machnicka MA, Nowacka M, Rother KM, Bujnicki JM

RNApathwaysDB – a database of RNA maturation and decay pathways

Nucleic Acids Res

Machnicka MA, Milanowska K, Osman Oglou O, Purta E, Kurkowska M, Olchowik A, Januszewski W, Kalinowski S, Dunin-Horkawicz S, Rother KM, Helm M, Bujnicki JM, Grosjean H

MODOMICS: a database of RNA modification pathways: 2013 update

Nucleic Acids Res

Nagalski A, Irimia M, Szewczyk L, Ferran JL, Misztal K, Kuznicki J, Wisniewska MB

Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain

Brain Struct Funct

Wojciechowski M, Czapinska H, Bochtler M

CpG Underrepresentation and the Bacterial CpG Specific DNA Methyltransferase M.MpeI

Proc Natl Acad Sci U S A.

Sztolsztener ME, Brewinska A, Guiard B, Chacinska A

Disulfide bond formation: sulfhydryl oxidase ALR controls mitochondrial biogenesis of human MIA40

Traffic

Pyrzynska B, Banach-Orlowska M, Teperek-Tkacz M, Miekus K, Drabik G, Majka M, Miaczynska M

Multifunctional protein APPL2 contributes to survival of human glioma cells

Mol Oncol.

Kraszewska MD, Dawidowska M, Kosmalska M, Sędek Ł, Grzeszczak W, Kowalczyk JR, Szczepański T, Witt M

BCL11B, FLT3, NOTCH1 and FBXW7 mutation status in T-cell Acute Lymphoblastic Leukemia patients

Blood Cells, Molecules and Diseases

Żylicz M.

Biologia syntetyczna: jak powstawało życie na Ziemi?

Nauka

2012

Pfeffer A, Chodakowska M, Czyżewski K, Gabryelewicz T, Łuczywek Ł, Mossakowska M, Broczek K, Barcikowska M

The Prevalence of Dementia in Warsaw Centenarians: a Population – Based Study

Postępy Nauk Medycznych

Kozlowski L, Orlowski J, Bujnicki JM

Structure prediction of alternatively spliced proteins In „Alternative pre-mRNA Splicing: Theory and Protocols: The Complete Guide for Biomedical Scientists”

Rother K, Rother M, Boniecki M, Puton T, Tomala K, Lukasz P, Bujnicki JM

Template-based and template-free modeling of RNA 3D structure: inspirations from protein structure modeling In "RNA Structure Prediction and Modelling"

Pulawski W, Ghoshdastider U, Andrisano V, Filipek S

Ubiquitous amyloids

Appl Biochem Biotechnol

Kozlowski LP, Bujnicki JM

MetaDisorder: A meta-server for the prediction of intrinsic disorder in proteins

BMC Bioinformatics

Kasprzak JM, Czerwoniec A, Bujnicki JM

Molecular evolution of dihydrouridine synthases

BMC Bioinformatics

Korneta I, Bujnicki JM

Intrinsic disorder in the human spliceosomal proteome

PLoS Comput Biol

Kusio-Kobialka M, Wolanin K, Podszywalow-Bartnicka P, Sikora E, Skowronek K, McKenna SL, Ghizzoni M, Dekker FJ, Piwocka K

Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage

Apoptosis

Roszczenko P, Radomska KA, Wywial E, Collet JF, Jagusztyn-Krynicka EK

A novel insight into the oxidoreductase activity of Helicobacter pylori HP0231 protein

PLoS One

Al-Haggar M, Madej-Pilarczyk A, Kozlowski L, Bujnicki JM, Yahia S, Abdel-Hadi D, Shams A, Ahmad N, Hamed S, Puzianowska-Kuznicka M

A novel homozygous p.Arg527Leu LMNA mutation in two unrelated egyptian families causes overlapping mandibuloacral dysplasia and progeria syndrome

Eur J Hum Genet

Naldi M, Fiori J, Pistolozzi M, Drake AF, Bertucci C, Wu R, Mlynarczyk K, Filipek S, De Simone A, Andrisano V

Amyloid β-Peptide 25-35 Self-Assembly and Its Inhibition: A Model Undecapeptide System to Gain Atomistic and Secondary Structure Details of the Alzheimer's Disease Process and Treatment

ACS Chem Neurosci

Yuan S, Ghoshdastider U, Trzaskowski B, Latek D, Debinski A, Pulawski W, Wu R, Gerke V, Filipek S

The Role of Water in Activation Mechanism of Human N-Formyl Peptide Receptor 1 (FPR1) Based on Molecular Dynamics Simulations

PLoS One

Magnus M, Pawlowski M, Bujnicki JM

MetaLocGramN: A meta-predictor of protein subcellular localization for Gram-negative bacteria

Biochim Biophys Acta

Laczmanski L, Milewicz A, Lwow F, Puzianowska-Kuznicka M, Pawlak M, Kolackov K, Jedrzejuk D, Krzyzanowska-Swiniarska B, Bar-Andziak E, Chudek J, Mossakowska M

Vitamin D receptor gene polymorphism and cardiovascular risk variables in elderly Polish subjects

Gynecol Endocrinol

Skalska A, Wizner B, Piotrowicz K, Klich-Rączka A, Klimek E, Mossakowska M, Rowiński R, Kozak-Szkopek E, Jóźwiak A, Gąsowski J, Grodzicki T

The prevalence of falls and their relation to visual and hearing impairments among a nation-wide cohort of older Poles

Exp Gerontol

Skowronek K, Boniecki MJ, Kluge B, Bujnicki JM

Rational engineering of sequence specificity in R.MwoI restriction endonuclease

Nucleic Acids Res

Poleszak K, Kaminska KH, Dunin-Horkawicz S, Lupas A, Skowronek KJ, Bujnicki JM

Delineation of structural domains and identification of functionally important residues in DNA repair enzyme Exonuclease VII

Nucleic Acids Res

Korneta I, Magnus M, Bujnicki JM

Structural bioinformatics of the human spliceosomal proteome

Nucleic Acids Res

Drozdz M, Piekarowicz A, Bujnicki JM, Radlinska M

Novel non-specific DNA adenine methyltransferases

Nucleic Acids Res

Sulej AA, Tuszynska I, Skowronek KJ, Nowotny M, Bujnicki JM

Sequence-specific cleavage of the RNA strand in DNA-RNA hybrids by the fusion of ribonuclease H with a zinc finger

Nucleic Acids Res

Pawlowski M, Bujnicki JM

The utility of comparative models and the local model quality for protein crystal structure determination by Molecular Replacement

BMC Bioinformatics

Pietal MJ, Szostak N, Rother KM, Bujnicki JM

RNAmap2D -- calculation, visualization and analysis of contact and distance maps for RNA and protein-RNA complex structures

BMC Bioinformatics

Bochtler M

Structural basis of the TAL effector-DNA interaction

Biol Chem

Wiech M, Olszewski MB, Tracz-Gaszewska Z, Wawrzynow B, Zylicz M, Zylicz A

Molecular Mechanism of Mutant p53 Stabilization: The Role of HSP70 and MDM2

PLoS One

Wisniewska MB, Nagalski A, Dabrowski M, Misztal K, Kuznicki J

Novel beta-catenin target genes identified in thalamic neurons encode modulators of neuronal excitability

BMC Genomics

Sabala I, Jonsson IM, Tarkowski A, Bochtler M

Anti-staphylococcal activities of lysostaphin and LytM catalytic domain

BMC Microbiol

Siwek W, Czapinska H, Bochtler M, Bujnicki JM, Skowronek K

Crystal structure and mechanism of action of the N6-methyladenine dependent type IIM restriction endonuclease

Nucleic Acids Res

Bukowy-Bieryłło Z, Ziętkiewicz E, Loges NT, Wittmer M, Geremek M, Olbrich H, Fliegauf M, Voelkel K, Rutkiewicz E, Rutland J, Morgan L, Pogorzelski A, Martin J, Haan E, Berger W, Omran H, Witt M

RPGR mutations might cause reduced orientation of respiratory cilia

Pediatr Pulmonol.

Winiarska M, Nowis D, Bil J, Glodkowska-Mrowka E, Muchowicz A, Wanczyk M, Bojarczuk K, Dwojak M, Firczuk M, Wilczek E, Wachowska M, Roszczenko K, Miaczynska M, Chlebowska J, Basak GW, Golab J

Prenyltransferases Regulate CD20 Protein Levels and Influence Anti-CD20 Monoclonal Antibody-mediated Activation of Complement-dependent Cytotoxicity

J Biol Chem

Böttinger L*, Gornicka A*, Czerwik T, Bragoszewski P, Loniewska-Lwowska A, Schulze-Specking A, Truscott KN, Guiard B, Milenkovic D, Chacinska A, *equally contributing first author

In vivo evidence for cooperation of Mia40 and Erv1 in the oxidation of mitochondrial proteins

Mol Biol Cell

Voegtle FN, Burkhart JM, Rao S, Gerbeth C, Hinrichs J, Martinou JC, Chacinska A, Sickmann A, Zahedi RP, Meisinger C

Intermembrane space proteome of yeast mitochondria

Mol Cell Proteomics

Bohnert M, Wenz LS, Zerbes RM, Horvath SE, Stroud DA, von der Malsburg K, Müller JM, Oeljeklaus S, Perschil I, Warscheid B, Chacinska A, Veenhuis M, van der Klei IJ, Daum G, Wiedemann N, Becker T, Pfanner N, van der Laan M

Role of MINOS in protein biogenesis of the mitochondrial outer membrane

Mol Biol Cell.

Knapska E, Macias M, Mikosz M, Nowak A, Owczarek D, Wawrzyniak M, Pieprzyk M, Cymerman IA, Werka T, Sheng M, Maren S, Jaworski J, Kaczmarek L

Functional anatomy of neural circuits regulating fear and extinction

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Green RA,Paluch E, Oegema K

Cytokinesis in Animal Cells

Annu Rev Cell Dev Biol.

Salbreux G, Charras G, Paluch E

Actin cortex mechanics and cellular morphogenesis

Trends Cell Biol.

Maître JL, Berthoumieux H, Krens SF, Salbreux G, Jülicher F, Paluch E, Heisenberg CP

Adhesion Functions in Cell Sorting by Mechanically Coupling the Cortices of Adhering Cells

Science

Bergert M, Chandradoss SD, Desai RA, Paluch E

Cell mechanics control rapid transitions between blebs and lamellipodia during migration

Proc Natl Acad Sci U S A

Zerrouqi A, Pyrzynska B, Febbraio M, Brat DJ, Van Meir EG

P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3

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Sosnowski TR, Koliński M, Gradoń L

Alteration of surface properties of dipalmitoyl phosphatidylcholine by benzo[a]pyrene: a model of pulmonary effects of diesel exhaust inhalation

J Biomed Nanotechnol

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Protein kinase C regulates amino acid transporter ATB

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Malenda A, Skrobanska A, Issat T, Winiarska M, Bil J, Oleszczak B, Sinski M, Firczuk M, Bujnicki JM, Chlebowska J, Staruch AD, Glodkowska-Mrowka E, Kunikowska J, Krolicki L, Szablewski L, Gaciong Z, Koziak K, Jakobisiak M, Golab J, Nowis DA

Statins Impair Glucose Uptake in Tumor Cells

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Lammens W, Le Roy K, Yuan S, Vergauwen R, Rabijns A, Van Laere A, Strelkov SV, Van den Ende W

Crystal structure of 6-SST/6-SFT from Pachysandra terminalis, a plant fructan biosynthesizing enzyme in complex with its acceptor substrate 6-kestose

Plant J.

Lach G, DeKievet M, Jentschura UD

Einstein–Hopf drag, Doppler shift of thermal radiation and blackbody drag: Three perspectives on quantum friction

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Goudarzi M, Banisch TU, Mobin MB, Maghelli N, Tarbashevich K, Strate I, van den Berg J, Blaser H, Bandemer S, Paluch E, Bakkers J, Tolić-Nørrelykke IM, Raz E

Identification and Regulation of a Molecular Module for Bleb-Based Cell Motility

Dev Cell

Fislage M, Roovers M, Tuszynska I, Bujnicki JM, Droogmans L, Versées W

Crystal structures of the tRNA:m(2)G6 methyltransferase Trm14/TrmN from two domains of life

Nucleic Acids Res

Cruz JA, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cao S, Das R, Ding F, Dokholyan NV, Flores SC, Huang L, Lavender CA, Lisi V, Major F, Mikolajczak K, Patel DJ, Philips A, Puton T, Santalucia J, Sijenyi F, Hermann T, Rother K, Rother M, Serganov A, Skorupski M, Soltysinski T, Sripakdeevong P, Tuszynska I, Weeks KM, Waldsich C, Wildauer M, Leontis NB, Westhof E

RNA-Puzzles: A CASP-like evaluation of RNA three-dimensional structure prediction

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Chojnowski G, Bujnicki JM, Bochtler M

RIBER/DIBER: a software suite for crystal content analysis in the studies of protein-nucleic acid complexes

Bioinformatics

Bialopiotrowicz E, Szybinska A, Kuzniewska B, Buizza L, Uberti D, Kuznicki J, Wojda U

Highly Pathogenic Alzheimer's Disease Presenilin 1 P117R Mutation Causes a specific Increase in p53 and p21 Protein Levels and Cell Cycle Dysregulation in Human Lymphocytes

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The MIA pathway: A tight bond between protein transport and oxidative folding in mitochondria

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BMC Mol Biol

Roovers M, Oudjama Y, Fislage M, Bujnicki JM, Versées W, Droogmans L

The open reading frame TTC1157 of Thermus thermophilus HB27 encodes the methyltransferase forming N2-methylguanosine at position 6 in tRNA

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Nakagome S, Mano S, Kozlowski L, Bujnicki JM, Shibata H, Fukumaki Y, Kidd JR, Kidd KK, Kawamura S, Oota H

Crohn's Disease Risk Alleles on the NOD2 Locus Have Been Maintained by Natural Selection on Standing Variation

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Structure and operation of the DNA-translocating type I DNA restriction enzymes

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MetalionRNA: computational predictor of metal-binding sites in RNA structures

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The mechanics of the cellular division or how to split a sphere into two?

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Mutations in radial spoke head genes and ultrastructural cilia defects in East-European cohort of primary ciliary dyskinesia patients

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Developmental plasticity of the dendritic compartment: focus on the cytoskeleton

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NMDA Receptor Activation Suppresses Microtubule Growth and Spine Entry

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Distinct molecular regulation of glycogen synthase kinase-3alpha isozyme controlled by its N-terminal region: functional role in calcium/calpain signaling

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Modeling of ligand binding to G protein coupled receptors: cannabinoid CB(1), CB (2) and adrenergic β (2)AR

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Arginine interactions with anatase TiO(2) (100) surface and the perturbation of (49)Ti NMR chemical shifts - a DFT investigation: relevance to Renu-Seeram bio solar cell

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Differential Roles for STIM1 and STIM2 in Store-Operated Calcium Entry in Rat Neurons

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Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth

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Bialopiotrowicz E, Kuzniewska B, Kachamakova-Trojanowska N, Barcikowska M, Kuznicki J, Wojda U

Cell cycle regulation distinguishes lymphocytes from sporadic and familial Alzheimer's disease patients

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Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit

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IGERS: inferring Gibbs energy changes of biochemical reactions from reaction similarities

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Kvardova V, Hrstka R, Walerych D, Muller P, Matoulkova E, Hruskova V, Stelclova D, Sova P, Vojtesek B

The new platinum(IV) derivative LA-12 shows stronger inhibitory effect on Hsp90 function compared to cisplatin

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Mitochondrial genotype and breast cancer predisposition

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Decreased expression and the Lys751Gln polymorphism of the XPD gene are associated with extreme longevity

Biogerontology

Adler G, Parczewski M, Czerska E, Loniewska B, Kaczmarczyk M, Gumprecht J, Grzeszczak W, Szybinska A, Mossakowska M, Ciechanowicz A

An age-related decrease in factor V Leiden frequency among Polish subjects

J Appl Genet

Klemba A, Kowalewska M, Kukwa W, Tonska K, Szybinska A, Mossakowska M, Scinska A, Golik P, Koper K, Radziszewski J, Kukwa A, Czarnecka AM, Bartnik E

Mitochondrial genotype in vulvar carcinoma - cuckoo in the nest

J Biomed Sci

Piechota M, Korostynski M, Solecki W, Gieryk A, Slezak M, Bilecki W, Ziolkowska B, Kostrzewa E, Cymerman I, Swiech L, Jaworski J, Przewlocki R

The dissection of transcriptional modules regulated by various drugs of abuse in the mouse striatum.

Genome Biol

Michowski W, Ferretti R, Wisniewska MB, Ambrozkiewicz M, Beresewicz M, Fusella F, Skibinska-Kijek A, Zablocka B, Brancaccio M, Tarone G, Kuznicki J

Morgana/CHP-1 is a novel chaperone able to protect cells from stress.

Biochim Biophys Acta

Wisniewska MB, Misztal K, Michowski W, Szczot M, Purta E, Lesniak W, Klejman ME, Dabrowski M, Filipkowski RK, Nagalski A, Mozrzymas JW, Kuznicki J

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain.

J Neurosci

Chojnowski G, Bochtler M

DIBER: protein, DNA or both?

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Alu-repeat-induced deletions within the NCF2 gene causing p67-phox-deficient chronic granulomatous disease (CGD)

Hum Mutat

Chojnowski G, Breer K, Narczyk M, Wielgus-Kutrowska B, Czapinska H, Hashimoto M, Hikishima S, Yokomatsu T, Bochtler M, Girstun A, Staroń K, Bzowska A

1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state

Biochem Biophys Res Commun

Diz-Muñoz A, Krieg M, Bergert M, Ibarlucea-Benitez I, Muller DJ, Paluch E, Heisenberg CP

Control of directed cell migration in vivo by membrane-to-cortex attachment.

PLoS Biol

Khan F, Furuta Y, Kawai M, Kaminska KH, Ishikawa K, Bujnicki JM, Kobayashi I

A putative mobile genetic element carrying a novel type IIF restriction-modification system (PluTI).

Nucleic Acids Res

Tuszynska I, Bujnicki JM

Predicting atomic details of the unfolding pathway for YibK, a knotted protein from the SPOUT superfamily

J Biomol Struct Dyn

Kaminska KH, Purta E, Hansen LH, Bujnicki JM, Vester B, Long KS

Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria.

Nucleic Acids Res

Zhou X, Chua TK, Tkaczuk KL, Bujnicki JM, Sivaraman J

The crystal structure of Escherichia coli spermidine synthase SpeE reveals a unique substrate-binding pocket.

J Struct Biol

Pukáncsik M, Békési A, Klement E, Hunyadi-Gulyás E, Medzihradszky KF, Kosinski J, Bujnicki JM, Alfonso C, Rivas G, Vértessy BG

Physiological truncation and domain organization of a novel uracil-DNA-degrading factor.

FEBS J

Zhang Z, Theler D, Kaminska KH, Hiller M, de la Grange P, Pudimat R, Rafalska I, Heinrich B, Bujnicki JM, Allain FH, Stamm S

The YTH domain is a novel RNA binding domain.

J Biol Chem

Pukszta S, Schilke B, Dutkiewicz R, Kominek J, Moczulska K, Stepien B, Reitenga KG, Bujnicki JM, Williams B, Craig EA, Marszalek J

Co-evolution-driven switch of J-protein specificity towards an Hsp70 partner.

EMBO Rep

Kempenaers M, Roovers M, Oudjama Y, Tkaczuk KL, Bujnicki JM, Droogmans L

New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA.

Nucleic Acids Res

Husain N, Tkaczuk KL, Tulsidas SR, Kaminska KH, Cubrilo S, Maravić-Vlahovicek G, Bujnicki JM, Sivaraman J

Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.

Nucleic Acids Res

Kosinski J, Hinrichsen I, Bujnicki JM, Friedhoff P, Plotz G

Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair.

Hum Mutat

Chua TK, Seetharaman J, Kasprzak JM, Ng C, Patel BK, Love C, Bujnicki JM, Sivaraman J

Crystal structure of a fructokinase homolog from Halothermothrix orenii

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Gajda MJ, Tuszynska I, Kaczor M, Bakulina AY, Bujnicki JM

FILTREST3D: discrimination of structural models using restraints from experimental data.

Bioinformatics

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Production and characterization of recombinant protein preparations of Endonuclease G-homologs from yeast, C. elegans and humans.

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Expression of Ttyh1, a member of the Tweety family in neurons in vitro and in vivo and its potential role in brain pathology.

J Neurochem

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Crystal structures of RNase H2 in complex with nucleic acid reveal the mechanism of RNA-DNA junction recognition and cleavage.

Mol Cell

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Signaling endosomes: seeing is believing

Curr Opin Cell Biol

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Study of a structurally similar kappa opioid receptor agonist and antagonist pair by molecular dynamics simulations.

J Mol Model

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Fizjologia i molekularny mechanizm działania glikokortykoidów

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Resistance of the dopamine D4 receptor to agonist-induced internalization and degradation.

Cell Signal

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Increased CD44 gene expression in lymphocytes derived from Alzheimer disease patients.

Neurodegener Dis

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In vitro findings of alterations in intracellular calcium homeostasis in schizophrenia.

Prog Neuropsychopharmacol Biol Psychiatry

Piano D, El Alaoui S, Korza HJ, Filipek R, Sabala I, Haniewicz P, Buechel C, De Sanctis D, Bochtler M

Crystallization of the Photosystem II core complex and its chlorophyll binding subunit CP43 from transplastomic plants of Nicotiana tabacum

Photosynth Res

Kirkegaard T, Roth AG, Petersen NH, Mahalka AK, Olsen OD, Moilanen I, Zylicz A, Knudsen J, Sandhoff K, Arenz C, Kinnunen PK, Nylandsted J, Jäättelä M

Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.

Nature

Zurawska A, Urbanski J, Matuliene J, Baraniak J, Klejman MP, Filipek S, Matulis D, Bieganowski P

Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo.

Biochim Biophys Acta

Walerych D, Gutkowska M, Klejman MP, Wawrzynow B, Tracz Z, Wiech M, Zylicz M, Zylicz A

ATP binding to Hsp90 is sufficient for effective chaperoning of p53 protein.

J Biol Chem

2009

Ohya T, Miaczynska M, Coskun U, Lommer B, Runge A, Drechsel D, Kalaidzidis Y, Zerial M

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.

Nature

Olchowik M, Miaczyńska M

[Effectors of GTPase Rab5 in endocytosis and signal transduction]

Postepy Biochem

Banach-Orlowska M, Pilecka I, Torun A, Pyrzynska B, Miaczynska M

Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex

Biochem J

Sadowski L, Pilecka I, Miaczynska M

Signaling from endosomes: location makes a difference.

Exp Cell Res

M. Kolinfski, S. Filipek

Studies of the Activation Steps Concurrent to Ligand Binding in δOR and κOR Opioid Receptors Based on Molecular Dynamics Simulations

TOSBJ

Kilanczyk E, Filipek S, Jastrzebska B, Filipek A

CacyBP/SIP binds ERK1/2 and affects transcriptional activity of Elk-1

Biochem Biophys Res Commun

Austermann J, Nazmi AR, Heil A, Fritz G, Kolinski M, Filipek S, Gerke V

Generation and characterization of a novel, permanently active S100P mutant.

Biochim Biophys Acta

Thavasi V, Lazarova T, Filipek S, Kolinski M, Querol E, Kumar A, Ramakrishna S, Padrós E, Renugopalakrishnan V

Study on the feasibility of bacteriorhodopsin as bio-photosensitizer in excitonic solar cell: a first report.

J Nanosci Nanotechnol

Kannan AM, Renugopalakrishnan V, Filipek S, Li P, Audette GF, Munukutla L

Bio-batteries and bio-fuel cells: leveraging on electronic charge transfer proteins.

J Nanosci Nanotechnol

V. Renugopalakrishnan, A. M. Kannan, S. Srinivasan, V. Thavasi, S. Ramakrishna, P. Li, A. Mershin, S. Filipek, A. Kumar, J. Dutta, A. Jaya, L. Munukutla, S. Velumani, G. F. Audette

“Nanomaterials for Energy Convertion Applications”

\"Nanomaterials for Energy Storage Applications\"

S. Filipek

“Bioinformatyka strukturalna białek transbłonowych”

Kosmos

Klejman ME, Gruszczynska-Biegala J, Skibinska-Kijek A, Wisniewska MB, Misztal K, Blazejczyk M, Bojarski L, Kuznicki J

Expression of STIM1 in brain and puncta-like co-localization of STIM1 and ORAI1 upon depletion of Ca(2+) store in neurons.

Neurochem Int

Skibinska-Kijek A, Wisniewska MB, Gruszczynska-Biegala J, Methner A, Kuznicki J

Immunolocalization of STIM1 in the mouse brain.

Acta Neurobiol Exp (Wars)

Bojarski L, Pomorski P, Szybinska A, Drab M, Skibinska-Kijek A, Gruszczynska-Biegala J, Kuznicki J

Presenilin-dependent expression of STIM proteins and dysregulation of capacitative Ca2+ entry in familial Alzheimer's disease.

Biochim Biophys Acta

Sokolowska M, Czapinska H, Bochtler M

Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA

Nucleic Acids Res

Majorek KA, Bujnicki JM

Modeling of Escherichia coli Endonuclease V structure in complex with DNA.

J Mol Model

Fink G, Hajdo L, Skowronek KJ, Reuther C, Kasprzak AA, Diez S

The mitotic kinesin-14 Ncd drives directional microtubule-microtubule sliding.

Nat Cell Biol

Czerwoniec A, Dunin-Horkawicz S, Purta E, Kaminska KH, Kasprzak JM, Bujnicki JM, Grosjean H, Rother K

MODOMICS: a database of RNA modification pathways. 2008 update

Nucleic Acids Res

Nakonieczna J, Kaczorowski T, Obarska-Kosinska A, Bujnicki JM

Functional analysis of MmeI from methanol utilizer Methylophilus methylotrophus, a subtype IIC restriction-modification enzyme related to type I enzymes.

Appl Environ Microbiol

Kennaway CK, Obarska-Kosinska A, White JH, Tuszynska I, Cooper LP, Bujnicki JM, Trinick J, Dryden DT

The structure of M.EcoKI Type I DNA methyltransferase with a DNA mimic antirestriction protein

Nucleic Acids Res

Pierechod M, Nowak A, Saari A, Purta E, Bujnicki JM, Konieczny I

Conformation of a plasmid replication initiator protein affects its proteolysis by ClpXP system

Protein Sci

Matsumoto Y, Oota H, Asaoka Y, Nishina H, Watanabe K, Bujnicki JM, Oda S, Kawamura S, Mitani H

Medaka: a promising model animal for comparative population genomics.

BMC Res Notes

Bauer RA, Rother K, Moor P, Reinert K, Steinke T, Bujnicki JM

Fast Structural Alignment of Biomolecules Using a Hash Table, N-Grams and String Descriptors

Algorithms

Purta E, O'Connor M, Bujnicki JM, Douthwaite S

YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA.

Mol Microbiol

Pawłowski M, Lasica AM, Jagusztyn-Krynicka EK, Bujnicki JM

AAN82231 protein from uropathogenic E. coli CFT073 is a close paralog of DsbB enzymes and does not belong to the DsbI family

Pol J Microbiol

Zylicz-Stachula A, Bujnicki JM, Skowron PM

Cloning and analysis of a bifunctional methyltransferase/restriction endonuclease TspGWI, the prototype of a Thermus sp. enzyme family.

BMC Mol Biol

Palfi Z, Jaé N, Preusser C, Kaminska KH, Bujnicki JM, Lee JH, Günzl A, Kambach C, Urlaub H, Bindereif A

SMN-assisted assembly of snRNP-specific Sm cores in trypanosomes.

Genes Dev

Pena V, Jovin SM, Fabrizio P, Orlowski J, Bujnicki JM, Lührmann R, Wahl MC

Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase.

Mol Cell

Kolmos E, Nowak M, Werner M, Fischer K, Schwarz G, Mathews S, Schoof H, Nagy F, Bujnicki JM, Davis SJ

Integrating ELF4 into the circadian system through combined structural and functional studies.

HFSP J

Leski TA, Caswell CC, Pawlowski M, Klinke DJ, Bujnicki JM, Hart SJ, Lukomski S

Identification and classification of bcl genes and proteins of Bacillus cereus group organisms and their application in Bacillus anthracis detection and fingerprinting.

Appl Environ Microbiol

Szymańska Z, Urbański J, Marciniak-Czochra A

Mathematical modelling of the influence of heat shock proteins on cancer invasion of tissue.

J Math Biol

Walerych D, Olszewski MB, Gutkowska M, Helwak A, Zylicz M, Zylicz A

Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions.

Oncogene

Narayan V, Eckert M, Zylicz A, Zylicz M, Ball KL

Cooperative regulation of the interferon regulatory factor-1 tumor suppressor protein by core components of the molecular chaperone machinery

J Biol Chem

Jaworski J, Kapitein LC, Gouveia SM, Dortland BR, Wulf PS, Grigoriev I, Camera P, Spangler SA, Di Stefano P, Demmers J, Krugers H, Defilippi P, Akhmanova A, Hoogenraad CC

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity.

Neuron

Blazejczyk M, Sobczak A, Debowska K, Wisniewska MB, Kirilenko A, Pikula S, Jaworski J, Kuznicki J, Wojda U

Biochemical characterization and expression analysis of a novel EF-hand Ca2+ binding protein calmyrin2 (Cib2) in brain indicates its function in NMDA receptor mediated Ca2+ signaling.

Arch Biochem Biophys

Nowotny M, Yang W

Structural and functional modules in RNA interference

Curr Opin Struct Biol

Nowotny M

Retroviral integrase superfamily: the structural perspective.

EMBO Rep

Rashid S, Pilecka I, Torun A, Olchowik M, Bielinska B, Miaczynska M

Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription.

J Biol Chem

Pyrzynska B, Pilecka I, Miaczynska M

Endocytic proteins in the regulation of nuclear signaling, transcription and tumorigenesis

Mol Oncol

Park PS, Sapra KT, Jastrzebska B, Maeda T, Maeda A, Pulawski W, Kono M, Lem J, Crouch RK, Filipek S, Müller DJ, Palczewski K

Modulation of molecular interactions and function by rhodopsin palmitylation

Biochemistry

J.S. Jaworski, A. Kosson, S. Filipek, M. Kolinski, D. Kuck

Properties of Radical Anions of Triptindanones and Indanones: Electronic Communication and Stability of Ion Pairs Containing Lithium Cations

J. Phys. Chem. C

Puzianowska-Kuznicka M, Kuznicki J.

The ER and ageing II: calcium homeostasis

Ageing Res Rev

Wawrzynow B, Pettersson S, Zylicz A, Bramham J, Worrall E, Hupp TR, Ball KL

A function for the RING finger domain in the allosteric control of MDM2 conformation and activity.

J Biol Chem

Szymańska Z, Zylicz M

Mathematical modeling of heat shock protein synthesis in response to temperature change.

J Theor Biol

2008

Geremek M, Schoenmaker F, Zietkiewicz E, Pogorzelski A, Diehl S, Wijmenga C, Witt M

Sequence analysis of 21 genes located in the Kartagener syndrome linkage region on chromosome 15q

Eur J Hum Genet

Dawidowska M, Jółkowska J, Szczepański T, Derwich K, Wachowiak J, Witt M

Implementation of the standard strategy for identification of Ig/TCR targets for minimal residual disease diagnostics in B-cell precursor ALL pediatric patients: Polish experience

Arch Immunol Ther Exp (Warsz)

Tomat E, Nolan EM, Jaworski J, Lippard SJ

Organelle-specific zinc detection using zinpyr-labeled fusion proteins in live cells

J Am Chem Soc

Rylski M, Amborska R, Zybura K, Mioduszewska B, Michaluk P, Jaworski J, Kaczmarek L

Yin Yang 1 is a critical repressor of matrix metalloproteinase-9 expression in brain neurons

J Biol Chem

Jaworski J, Hoogenraad CC, Akhmanova A

Microtubule plus-end tracking proteins in differentiated mammalian cells.

Int J Biochem Cell Biol

Swiech L, Perycz M, Malik A, Jaworski J

Role of mTOR in physiology and pathology of the nervous system

Biochim Biophys Acta

Macias M

Injury induced dendritic plasticity in the mature central nervous system.

Acta Neurobiol Exp (Wars)

Urbanska M, Blazejczyk M, Jaworski J

Molecular basis of dendritic arborization

Acta Neurobiol Exp (Wars)

Mioduszewska B, Jaworski J, Szklarczyk AW, Klejman A, Kaczmarek L

Inducible cAMP early repressor (ICER)-evoked delayed neuronal death in the organotypic hippocampal culture

J Neurosci Res

Kubiak JZ, Ciemerych MA, Hupalowska A, Sikora-Polaczek M, Polanski Z

On the transition from the meiotic to mitotic cell cycle during early mouse development.

Int J Dev Biol

Miaczynska M, Stenmark H

Mechanisms and functions of endocytosis.

J Cell Biol

Kolinski M, Filipek S.

Molecular dynamics of mu opioid receptor complexes with agonists and antagonists

The Open Struct. Biol. J.

Jozwiak K, Krzysko KA, Bojarski L, Gacia M, Filipek S

Molecular models of the interface between anterior pharynx-defective protein 1 (APH-1) and presenilin involving GxxxG motifs

ChemMedChem

Bhatia P, Kolinski M, Moaddel R, Jozwiak K, Wainer IW

Determination and modelling of stereoselective interactions of ligands with drug transporters: a key dimension in the understanding of drug disposition

Xenobiotica

Stephen R, Filipek S, Palczewski K, Sousa MC

Ca2+ -dependent regulation of phototransduction.

Photochem Photobiol

Majewski T, Lee S, Jeong J, Yoon DS, Kram A, Kim MS, Tuziak T, Bondaruk J, Lee S, Park WS, Tang KS, Chung W, Shen L, Ahmed SS, Johnston DA, Grossman HB, Dinney CP, Zhou JH, Harris RA, Snyder C, Filipek S, Narod SA, Watson P, Lynch HT, Gazdar A, Bar-Eli M,

Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy.

Lab Invest

Erickson RP, Larson-Thomé K, Weberg L, Szybinska A, Mossakowska M, Styczynska M, Barcikowska M, Kuznicki J

Variation in NPC1, the gene encoding Niemann-Pick C1, a protein involved in intracellular cholesterol transport, is associated with Alzheimer disease and/or aging in the Polish population

Neurosci Lett

Winiarska M, Bil J, Wilczek E, Wilczynski GM, Lekka M, Engelberts PJ, Mackus WJ, Gorska E, Bojarski L, Stoklosa T, Nowis D, Kurzaj Z, Makowski M, Glodkowska E, Issat T, Mrowka P, Lasek W, Dabrowska-Iwanicka A, Basak GW, Wasik M, Warzocha K, Sinski M, Gaci

Statins impair antitumor effects of rituximab by inducing conformational changes of CD20.

PLoS Med

Mossakowska M, Barcikowska M, Broczek K, Grodzicki T, Klich-Raczka A, Kupisz-Urbanska M, Podsiadly-Marczykowska T, Sikora E, Szybinska A, Wieczorowska-Tobis K, Zyczkowska J, Kuznicki J

Polish Centenarians Programme. Multidisciplinary studies of successful ageing: aims, methods, and preliminary results

Exp Gerontol

Bojarski L, Herms J, Kuznicki J

Calcium dysregulation in Alzheimer's disease

Neurochem Int

Wojda U, Salinska E, Kuznicki J

Calcium ions in neuronal degeneration

IUBMB Life

Lanni C, Racchi M, Mazzini G, Ranzenigo A, Polotti R, Sinforiani E, Olivari L, Barcikowska M, Styczynska M, Kuznicki J, Szybinska A, Govoni S, Memo M, Uberti D

Conformationally altered p53: a novel Alzheimer's disease marker?

Mol Psychiatry

Zabka M, Leśniak W, Prus W, Kuźnicki J, Filipek A

Sgt1 has co-chaperone properties and is up-regulated by heat shock.

Biochem Biophys Res Commun

Filipek A, Michowski W, Kuznicki J

Involvement of S100A6 (calcyclin) and its binding partners in intracellular signaling pathways

Adv Enzyme Regul

Blazejczyk M, Wojda U

Factfile: Calmyrin 1 (review)

Calcium Binding Proteins

Szczepanowski RH, Carpenter MA, Czapinska H, Zaremba M, Tamulaitis G, Siksnys V, Bhagwat AS, Bochtler M

Central base pair flipping and discrimination by PspGI

Nucleic Acids Res

Tamulaitis G, Zaremba M, Szczepanowski RH, Bochtler M, Siksnys V

How PspGI, catalytic domain of EcoRII and Ecl18kI acquire specificities for different DNA targets

Nucleic Acids Res

Breer K, Wielgus-Kutrowska B, Hashimoto M, Hikishima S, Yokomatsu T, Szczepanowski RH, Bochtler M, Girstun A, Starón K, Bzowska A

Thermodynamic studies of interactions of calf spleen PNP with acyclic phosphonate inhibitors

Nucleic Acids Symp Ser (Oxf)

Sukackaite R, Grazulis S, Bochtler M, Siksnys V.

The recognition domain of the BpuJI restriction endonuclease in complex with cognate DNA at 1.3-A resolution

J Mol Biol

Lipka M, Filipek R, Bochtler M

Crystal structure and mechanism of the Staphylococcus cohnii virginiamycin B lyase (Vgb)

Biochemistry

Maravić Vlahovicek G, Cubrilo S, Tkaczuk KL, Bujnicki JM

Modeling and experimental analyses reveal a two-domain structure and amino acids important for the activity of aminoglycoside resistance methyltransferase Sgm.

Biochim Biophys Acta

Vasu K, Saravanan M, Bujnicki JM, Nagaraja V

Structural integrity of the beta beta alpha-Metal finger motif is required for DNA binding and stable protein-DNA complex formation in R.KpnI.

Biochim Biophys Acta

Kaminska KH, Baraniak U, Boniecki M, Nowaczyk K, Czerwoniec A, Bujnicki JM

Structural bioinformatics analysis of enzymes involved in the biosynthesis pathway of the hypermodified nucleoside ms(2)io(6)A37 in tRNA.

Proteins

Roovers M, Oudjama Y, Kaminska KH, Purta E, Caillet J, Droogmans L, Bujnicki JM

Sequence-structure-function analysis of the bifunctional enzyme MnmC that catalyses the last two steps in the biosynthesis of hypermodified nucleoside mnm5s2U in tRNA.

Proteins

Kaminska KH, Bujnicki JM

Bacteriophage Mu Mom protein responsible for DNA modification is a new member of the acyltransferase superfamily.

Cell Cycle

Mittra B, Zamudio JR, Bujnicki JM, Stepinski J, Darzynkiewicz E, Campbell DA, Sturm NR

The TbMTr1 spliced leader RNA cap 1 2'-O-ribose methyltransferase from Trypanosoma brucei acts with substrate specificity

J Biol Chem

Feder M, Purta E, Koscinski L, Cubrilo S, Maravic Vlahovicek G, Bujnicki JM

Virtual screening and experimental verification to identify potential inhibitors of the ErmC methyltransferase responsible for bacterial resistance against macrolide antibiotics.

ChemMedChem

Bhagwat AS, Carpenter MA, Bujnicki JM

Is AID a monomer in solution?

DNA Repair (Amst)

Cymerman IA, Chung I, Beckmann BM, Bujnicki JM, Meiss G

EXOG, a novel paralog of Endonuclease G in higher eukaryotes.

Nucleic Acids Res

Sen TZ, Kloster M, Jernigan RL, Kolinski A, Bujnicki JM, Kloczkowski A

Predicting the complex structure and functional motions of the outer membrane transporter and signal transducer FecA.

Biophys J

Chua TK, Bujnicki JM, Tan TC, Huynh F, Patel BK, Sivaraman J

The structure of sucrose phosphate synthase from Halothermothrix orenii reveals its mechanism of action and binding mode.

Plant Cell

Roovers M, Kaminska KH, Tkaczuk KL, Gigot D, Droogmans L, Bujnicki JM

The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK).

Nucleic Acids Res

Orlowski J, Bujnicki JM

Structural and evolutionary classification of Type II restriction enzymes based on theoretical and experimental analyses.

Nucleic Acids Res

White J, Li Z, Sardana R, Bujnicki JM, Marcotte EM, Johnson AW

Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits.

Mol Cell Biol

Kosinski J, Plotz G, Guarné A, Bujnicki JM, Friedhoff P

The PMS2 subunit of human MutLalpha contains a metal ion binding domain of the iron-dependent repressor protein family.

J Mol Biol

Purta E, Kaminska KH, Kasprzak JM, Bujnicki JM, Douthwaite S

YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.

RNA

Pawlowski M, Gajda MJ, Matlak R, Bujnicki JM

MetaMQAP: a meta-server for the quality assessment of protein models.

BMC Bioinformatics

Sunita S, Tkaczuk KL, Purta E, Kasprzak JM, Douthwaite S, Bujnicki JM, Sivaraman J

Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes.

J Mol Biol

Obarska-Kosinska A, Taylor JE, Callow P, Orlowski J, Bujnicki JM, Kneale GG

HsdR subunit of the type I restriction-modification enzyme EcoR124I: biophysical characterisation and structural modelling.

J Mol Biol

Purta E, O\'Connor M, Bujnicki JM, Douthwaite S

YccW is the m5C methyltransferase specific for 23S rRNA nucleotide 1962

J Mol Biol

Gyrd-Hansen M, Darding M, Miasari M, Santoro MM, Zender L, Xue W, Tenev T, da Fonseca PC, Zvelebil M, Bujnicki JM, Lowe S, Silke J, Meier P

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis.

Nat Cell Biol

Orlowski J, Mebrhatu MT, Michiels CW, Bujnicki JM, Aertsen A

Mutational analysis and a structural model of methyl-directed restriction enzyme Mrr.

Biochem Biophys Res Commun

Guranowski A, Wojdyła AM, Pietrowska-Borek M, Bieganowski P, Khurs EN, Cliff MJ, Blackburn GM, Błaziak D, Stec WJ

Fhit proteins can also recognize substrates other than dinucleoside polyphosphates.

FEBS Lett

Sbroggiò M, Ferretti R, Percivalle E, Gutkowska M, Zylicz A, Michowski W, Kuznicki J, Accornero F, Pacchioni B, Lanfranchi G, Hamm J, Turco E, Silengo L, Tarone G, Brancaccio M

The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1.

FEBS Lett

Stevens C, Pettersson S, Wawrzynow B, Wallace M, Ball K, Zylicz A, Hupp TR

ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1.

FEBS J

Zurawska A, Urbanski J, Bieganowski P

Hsp90n - An accidental product of a fortuitous chromosomal translocation rather than a regular Hsp90 family member of human proteome

Biochim Biophys Acta

2007

Kołłajtis-Dołowy A, Pietruszka B, Kałuza J, Pawlińiska-Chmara R, Broczek K, Mossakowska M

The nutritional habits among centenarians living in Warsaw

Rocz Panstw Zakl Hig

Baranowska B, Wolinska-Witort E, Bik W, Baranowska-Bik A, Martynska L, Broczek K, Mossakowska M, Chmielowska M

Evaluation of neuroendocrine status in longevity

Neurobiol Aging

Wojda A, Zietkiewicz E, Witt M

Effects of age and gender on micronucleus and chromosome nondisjunction frequencies in centenarians and younger subjects

Mutagenesis

Jaworski J

ARF6 in the nervous system.

Eur J Cell Biol

Michaluk P, Kolodziej L, Mioduszewska B, Wilczynski GM, Dzwonek J, Jaworski J, Gorecki DC, Ottersen OP, Kaczmarek L

Beta-dystroglycan as a target for MMP-9, in response to enhanced neuronal activity.

J Biol Chem

Okulski P, Jay TM, Jaworski J, Duniec K, Dzwonek J, Konopacki FA, Wilczynski GM, Sánchez-Capelo A, Mallet J, Kaczmarek L

TIMP-1 abolishes MMP-9-dependent long-lasting long-term potentiation in the prefrontal cortex.

Biol Psychiatry

Pilecka I, Banach-Orlowska M, Miaczynska M

Nuclear functions of endocytic proteins

Eur J Cell Biol

Golan MP, Styczyńska M, Jóźwiak K, Walecki J, Maruszak A, Pniewski J, Lugiewicz R, Filipek S, Zekanowski C, Barcikowska M

Early-onset Alzheimer's disease with a de novo mutation in the presenilin 1 gene

Exp Neurol

Krzysko KA, Kolinski M, Filipek S.

Molecular modelling of the complex of oligomeric rhodopsin and its G protein.

J Phys Condens Matter

Lee S, Jeong J, Majewski T, Scherer SE, Kim MS, Tuziak T, Tang KS, Baggerly K, Grossman HB, Zhou JH, Shen L, Bondaruk J, Ahmed SS, Samanta S, Spiess P, Wu X, Filipek S, McConkey D, Bar-Eli M, Issa JP, Benedict WF, Czerniak B

Forerunner genes contiguous to RB1 contribute to the development of in situ neoplasia.

Proc Natl Acad Sci U S A

Park PS, Sapra KT, Koliński M, Filipek S, Palczewski K, Muller DJ

Stabilizing effect of Zn2+ in native bovine rhodopsin

J Biol Chem

Bojarski L, Lewandowicz A, Blazejczyk M, Sobczak A, Kuznicki J, Wojda U

Biochemical properties of endogenous presenilin 1 and presenilin 2 in cultured human B-lymphocytes

Clin Chem Lab Med

Leśniak W, Słomnicki ŁP, Kuźnicki J

Epigenetic control of the S100A6 (calcyclin) gene expression

J Invest Dermatol

Schneider G, Nieznanski K, Kilanczyk E,Bieganowski P, Kuznicki J, Filipek A

CacyBP/SIP interacts with tubulin in neuroblastoma NB2a cells and induces formation of globular tubulin assemblies

Biochim Biophys Acta

Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J,Filipek A

Hsp70 is a new target of Sgt1-an interaction modulated by S100A6

Biochem Biophys Res Commun

Wollmer MA, Sleegers K, Ingelsson M, Zekanowski C, Brouwers N, Maruszak A, Brunner F, Huynh KD, Kilander L, Brundin RM, Hedlund M, Giedraitis V, Glaser A, Engelborghs S, De Deyn PP, Kapaki E, Tsolaki M, Daniilidou M, Molyva D, Paraskevas GP, Thal DR, Barc

Association study of cholesterol-related genes in Alzheimer's disease

Neurogenetics

Bochtler M, Chojnowski G

The highest reflection intensity in a resolution shell

Acta Crystallogr A

Chojnowski G, Bochtler M

The statistics of the highest E value

Acta Crystallogr A

Firczuk M, Bochtler M

Folds and activities of peptidoglycan amidases

FEMS Microbiol Rev

Firczuk M, Bochtler M

Mutational analysis of peptidoglycan amidase MepA

Biochemistry

Kaus-Drobek M, Czapinska H, Sokołowska M, Tamulaitis G, Szczepanowski RH, Urbanke C, Siksnys V, Bochtler M

Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically

Nucleic Acids Res

Sokolowska M, Kaus-Drobek M, Czapinska H, Tamulaitis G, Siksnys V, Bochtler M

Restriction endonucleases that resemble a component of the bacterial DNA repair machinery

Cell Mol Life Sci

Sokolowska M, Kaus-Drobek M, Czapinska H, Tamulaitis G, Szczepanowski RH, Urbanke C, Siksnys V, Bochtler M

Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA.

J Mol Biol

Tamulaitis G, Zaremba M, Szczepanowski RH, Bochtler M, Siksnys V

Nucleotide flipping by restriction enzymes analyzed by 2-aminopurine steady-state fluorescence

Nucleic Acids Res

Zamudio JR, Mittra B, Foldynová-Trantírková S, Zeiner GM, Lukes J, Bujnicki JM, Sturm NR, Campbell DA

The 2'-O-ribose methyltransferase for cap 1 of spliced leader RNA and U1 small nuclear RNA in Trypanosoma brucei

Mol Cell Biol

Tkaczuk KL, Dunin-Horkawicz S, Purta E, Bujnicki JM

Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.

BMC Bioinformatics

Sunita S, Purta E, Durawa M, Tkaczuk KL, Swaathi J, Bujnicki JM, Sivaraman J

Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC.

Nucleic Acids Res

Schäfer P, Cymerman IA, Bujnicki JM, Meiss G

Human lysosomal DNase IIalpha contains two requisite PLD-signature (HxK) motifs: evidence for a pseudodimeric structure of the active enzyme species.

Protein Sci

Sasin JM, Godzik A, Bujnicki JM

SURF'S UP! - protein classification by surface comparisons

J Biosci

Sabates-Bellver J, Van der Flier LG, de Palo M, Cattaneo E, Maake C, Rehrauer H, Laczko E, Kurowski MA, Bujnicki JM, Menigatti M, Luz J, Ranalli TV, Gomes V, Pastorelli A, Faggiani R, Anti M, Jiricny J, Clevers H, Marra G

Transcriptome profile of human colorectal adenomas.

Mol Cancer Res

Pietal MJ, Tuszynska I, Bujnicki JM

PROTMAP2D: visualization, comparison and analysis of 2D maps of protein structure.

Bioinformatics

Pena V, Liu S, Bujnicki JM, Lührmann R, Wahl MC

Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa.

Mol Cell

Ozanick SG, Bujnicki JM, Sem DS, Anderson JT

Conserved amino acids in each subunit of the heteroligomeric tRNA m1A58 Mtase from Saccharomyces cerevisiae contribute to tRNA binding.

Nucleic Acids Res

Orlowski J, Boniecki M, Bujnicki JM

I-Ssp6803I: the first homing endonuclease from the PD-(D/E)XK superfamily exhibits an unusual mode of DNA recognition

Bioinformatics

Miyazono K, Watanabe M, Kosinski J, Ishikawa K, Kamo M, Sawasaki T, Nagata K, Bujnicki JM, Endo Y, Tanokura M, Kobayashi I

Novel protein fold discovered in the PabI family of restriction enzymes.

Nucleic Acids Res

Liu Y, Li Z, Lin Q, Kosinski J, Seetharaman J, Bujnicki JM, Sivaraman J, Hew CL

Structure and evolutionary origin of Ca(2+)-dependent herring type II antifreeze protein.

PLoS One

Kudan EV, Brevnov MG, Subach OM, Rechkoblit OA, Buĭnitskiĭ IaM, Gromova ES

[Probing of contacts between EcoRII DNA methyltransferase and DNA using substrate analogs and molecular modeling].

Mol Biol (Mosk)

Kosinski J, Kubareva E, Bujnicki JM

A model of restriction endonuclease MvaI in complex with DNA: a template for interpretation of experimental data and a guide for specificity engineering.

Proteins

Koscinski L, Feder M, Bujnicki JM

Identification of a missing sequence and functionally important residues of 16S rRNA:m(1)A1408 methyltransferase KamB that causes bacterial resistance to aminoglycoside antibiotics.

Cell Cycle

Jakubauskas A, Giedriene J, Bujnicki JM, Janulaitis A

Identification of a single HNH active site in type IIS restriction endonuclease Eco31I

J Mol Biol

Ibryashkina EM, Zakharova MV, Baskunov VB, Bogdanova ES, Nagornykh MO, Den\'mukhamedov MM, Melnik BS, Kolinski A, Gront D, Feder M, Solonin AS, Bujnicki JM

Type II restriction endonuclease R.Eco29kI is a member of the GIY-YIG nuclease superfamily.

BMC Struct Biol

Chovancová E, Kosinski J, Bujnicki JM, Damborský J

Phylogenetic analysis of haloalkane dehalogenases.

Proteins

Schneider G, Nieznanski K, Kilanczyk E, Bieganowski P, Kuznicki J, Filipek A

CacyBP/SIP interacts with tubulin in neuroblastoma NB2a cells and induces formation of globular tubulin assemblies.

Biochim Biophys Acta

Wawrzynow B, Zylicz A, Wallace M, Hupp T, Zylicz M

MDM2 chaperones the p53 tumor suppressor.

J Biol Chem

Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J, Filipek A

Hsp70 is a new target of Sgt1--an interaction modulated by S100A6

Biochem Biophys Res Commun

Issat T, Nowis D, Legat M, Makowski M, Klejman MP, Urbanski J, Skierski J, Koronkiewicz M, Stoklosa T, Brzezinska A, Bil J, Gietka J, Jakóbisiak M, Golab J

Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.

Int J Oncol

Schneider G, Nieznanski K, Kilanczyk E, Bieganowski P, Kuznicki J, Filipek A

CacyBP/SIP interacts with tubulin in neuroblastoma NB2a cells and induces formation of globular tubulin assemblies.

Biochim Biophys Acta

Wawrzynow B, Zylicz A, Wallace M, Hupp T, Zylicz M

MDM2 chaperones the p53 tumor suppressor.

J Biol Chem

Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J, Filipek A

Hsp70 is a new target of Sgt1--an interaction modulated by S100A6.

Biochem Biophys Res Commun

Issat T, Nowis D, Legat M, Makowski M, Klejman MP, Urbanski J, Skierski J, Koronkiewicz M, Stoklosa T, Brzezinska A, Bil J, Gietka J, Jakóbisiak M, Golab J

Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.

Int J Oncol

2006

Kupisz-Urbańska M, Broczek K, Mossakowska M

Ocena sprawności ruchowej polskich stulatków – wybrane zagadnienia

Gerontologia Polska

Mossakowska M, Broczek K, Rajska-Neumann A, Wieczorowska-Tobis K

Jak często i jak dużo palili polscy stulatkowie

Przegląd Lekarski

Pawlinska-Chmara R, Mossakowska M

Ocena stanu uzębienia i użytkowych uzupełnień protetycznych polskich ludzi długowiecznych

Ann Univ M. Curie-Sklodowska

Podkówka-Sieczka R, Niemir Z, Mossakowska M, Sawiński K, Wieczorowska-Tobis K

Analiza leukocytów krwi obwodowej osób stuletnich

Przegląd Lekarski

Styczyński A, Wieczorowska-Tobis K, Niemir Z, Podkówka R, Mossakowska M

Czy istnieje związek między stężeniem w surowicy interleukiny-8 i zaburzeniami funkcji poznawczych u osób stuletnich?

Przegląd Lekarski

Wieczorowska-Tobis K, Niemir ZI, Podkówka R, Korybalska K, Mossakowska M, Breborowicz A

Can an increased level of circulating IL-8 be a predictor of human longevity?

Med Sci Monit

Wojda A, Zietkiewicz E, Mossakowska M, Pawłowski W, Skrzypczak K, Witt M

Correlation between the level of cytogenetic aberrations in cultured human lymphocytes and the age and gender of donors

J Gerontol A Biol Sci Med Sci

Pietruszka B, Kollajtis-Dolowy A, Szulc K, Kaluza J, Broczek K, Pawlinska-Chmara R, Mossakowska M

Characteristics of nutrition among centenarians living in Warsaw

Pol J Food Nutr Sci

Kempa K, Kłapcińska B, Mossakowska M, Broczek K, Sadowska-Krępa E, Derejczyk J, Kimsa E

Functional abilities and antioxidant defense status in female centenarians

Annales Universitatis Mariae Curie-Skłaodowska


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Wojcik M, Seidle HF, Bieganowski P, Brenner C

Glutamine-dependent NAD+ synthetase. How a two-domain, three-substrate enzyme avoids waste.

J Biol Chem

Jaworski J, Sheng M

The growing role of mTOR in neuronal development and plasticity

Mol Neurobiol

Nolan EM, Ryu JW, Jaworski J, Feazell RP, Sheng M, Lippard SJ

Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization.

J Am Chem Soc

Szymczak S, Kalita K, Jaworski J, Mioduszewska B, Savonenko A, Markowska A, Merchenthaler I, Kaczmarek L

Increased estrogen receptor beta expression correlates with decreased spine formation in the rat hippocampus

Hippocampus

Cieplak M, Filipek S, Janovjak H, Krzyśko KA

Pulling single bacteriorhodopsin out of a membrane: Comparison of simulation and experiment.

Biochim Biophys Acta

Jozwiak K, Zekanowski C, Filipek S

Linear patterns of Alzheimer's disease mutations along alpha-helices of presenilins as a tool for PS-1 model construction

J Neurochem

Modzelewska A, Filipek S, Palczewski K, Park PS

Arrestin interaction with rhodopsin: conceptual models.

Cell Biochem Biophys

Tanuj Sapra K, Park PS, Filipek S, Engel A, Müller DJ, Palczewski K

Detecting molecular interactions that stabilize native bovine rhodopsin

J Mol Biol

Zekanowski C, Golan MP, Krzyśko KA, Lipczyńska-Łojkowska W, Filipek S, Kowalska A, Rossa G, Pepłońska B, Styczyńska M, Maruszak A, Religa D, Wender M, Kulczycki J, Barcikowska M, Kuźnicki J

Two novel presenilin 1 gene mutations connected with frontotemporal dementia-like clinical phenotype: genetic and bioinformatic assessment.

Exp Neurol

Zhu L, Imanishi Y, Filipek S, Alekseev A, Jastrzebska B, Sun W, Saperstein DA, Palczewski K

Autosomal recessive retinitis pigmentosa and E150K mutation in the opsin gene.

J Biol Chem

Jaworski JS, Cembor M, Koliński M

Electrostatic model of bond dissociation energies in polyhalogen methanes

J Phys Org Chem

Groves P, Palczewska M, Kuznicki J

Calretinin, an EF-hand calcium-binding proteins, binds zinc and Cooper

Calcium Binding Proteins

Leśniak W, Kuźnicki J

Binding and functional characteristics of two E-box motifs within the S100A6 (calcyclin) gene promoter.

J Cell Biochem

Spiechowicz M, Bernstein HG, Dobrowolny H, Leśniak W, Mawrin C, Bogerts B, Kuźnicki J, Filipek A

Density of Sgt1-immunopositive neurons is decreased in the cerebral cortex of Alzheimer's disease brain.

Neurochem Int

Baranowska B, Bik W, Baranowska-Bik A, Wolinska-Witort E, Szybinska A, Martynska L, Chmielowska M

Neuroendocrine control of metabolic homeostasis in Polish centenarians

J Physiol Pharmacol

Bik W, Baranowska-Bik A, Wolinska-Witort E, Martynska L, Chmielowska M, Szybinska A, Broczek K, Baranowska B

The relationship between adiponectin levels and metabolic status in centenarian, early elderly, young and obese women

Neuro Endocrinol Lett

Blazejczyk M, Wojda U, Sobczak A, Spilker C, Bernstein HG, Gundelfinger ED, Kreutz MR, Kuznicki J

Ca2+-independent binding and cellular expression profiles question a significant role of calmyrin in transduction of Ca2+-signals to Alzheimer's disease-related presenilin 2 in forebrain

Biochim Biophys Acta

Bochtler M, Szczepanowski RH, Tamulaitis G, Grazulis S, Czapinska H, Manakova E, Siksnys V

Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease

EMBO J

Zegers I, Gigot D, van Vliet F, Tricot C, Aymerich S, Bujnicki JM, Kosinski J, Droogmans L

Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.

Nucleic Acids Res

Zamudio JR, Mittra B, Zeiner GM, Feder M, Bujnicki JM, Sturm NR, Campbell DA

Complete cap 4 formation is not required for viability in Trypanosoma brucei.

Eukaryot Cell

Tkaczuk KL, Obarska A, Bujnicki JM

Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis.

BMC Evol Biol

Skowronek KJ, Kosinski J, Bujnicki JM

Theoretical model of restriction endonuclease HpaI in complex with DNA, predicted by fold recognition and validated by site-directed mutagenesis.

Proteins

Sikora E, Bielak-Zmijewska A, Magalska A, Piwocka K, Mosieniak G, Kalinowska M, Widlak P, Cymerman IA, Bujnicki JM

Curcumin induces caspase-3-dependent apoptotic pathway but inhibits DNA fragmentation factor 40/caspase-activated DNase endonuclease in human Jurkat cells.

Mol Cancer Ther

Samaranayake M, Bujnicki JM, Carpenter M, Bhagwat AS

Evaluation of molecular models for the affinity maturation of antibodies: roles of cytosine deamination by AID and DNA repair.

Chem Rev

Purta E, van Vliet F, Tkaczuk KL, Dunin-Horkawicz S, Mori H, Droogmans L, Bujnicki JM

The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase.

BMC Mol Biol

Obarska A, Blundell A, Feder M, Vejsadová S, Sisáková E, Weiserová M, Bujnicki JM, Firman K

Structural model for the multisubunit Type IC restriction-modification DNA methyltransferase M.EcoR124I in complex with DNA.

Nucleic Acids Res

Mikula M, Karczmarski J, Dzwonek A, Rubel T, Hennig E, Dadlez M, Bujnicki JM, Bomsztyk K, Ostrowski J

Casein kinases phosphorylate multiple residues spanning the entire hnRNP K length.

Biochim Biophys Acta

Metz J, Wächter A, Schmidt B, Bujnicki JM, Schwappach B

The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol.

J Biol Chem

Klimek-Tomczak K, Mikula M, Dzwonek A, Paziewska A, Karczmarski J, Hennig E, Bujnicki JM, Bragoszewski P, Denisenko O, Bomsztyk K, Ostrowski J

Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa.

Br J Cancer

Han R, Caswell CC, Lukomska E, Keene DR, Pawlowski M, Bujnicki JM, Kim JK, Lukomski S

Binding of the low-density lipoprotein by streptococcal collagen-like protein Scl1 of Streptococcus pyogenes.

Mol Microbiol

Gros L, Renodon-Cornière A, de Saint Vincent BR, Feder M, Bujnicki JM, Jacquemin-Sablon A

Characterization of prmt7alpha and beta isozymes from Chinese hamster cells sensitive and resistant to topoisomerase II inhibitors.

Biochim Biophys Acta

Godlewska R, Dzwonek A, Mikuła M, Ostrowski J, Pawłowski M, Bujnicki JM, Jagusztyn-Krynicka EK

Helicobacter pylori protein oxidation influences the colonization process.

Int J Med Microbiol

Gabant G, Auxilien S, Tuszynska I, Locard M, Gajda MJ, Chaussinand G, Fernandez B, Dedieu A, Grosjean H, Golinelli-Pimpaneau B, Bujnicki JM, Armengaud J

THUMP from archaeal tRNA:m22G10 methyltransferase, a genuine autonomously folding domain.

Nucleic Acids Res

Dunin-Horkawicz S, Feder M, Bujnicki JM

Phylogenomic analysis of the GIY-YIG nuclease superfamily.

BMC Genomics

Cymerman IA, Obarska A, Skowronek KJ, Lubys A, Bujnicki JM

Identification of a new subfamily of HNH nucleases and experimental characterization of a representative member, HphI restriction endonuclease

Proteins

Chiang PK, Bujnicki JM, Su X, Lanar DE

Malaria: therapy, genes and vaccines.

Curr Mol Med

Carpenter M, Divvela P, Pingoud V, Bujnicki J, Bhagwat AS

Sequence-dependent enhancement of hydrolytic deamination of cytosines in DNA by the restriction enzyme PspGI.

Nucleic Acids Res

Bujnicki JM

Protein-structure prediction by recombination of fragments.

Chembiochem

Bheemanaik S, Bujnicki JM, Nagaraja V, Rao DN

Functional analysis of amino acid residues at the dimerisation interface of KpnI DNA methyltransferase.

Biol Chem

Dunin-Horkawicz S, Czerwoniec A, Gajda MJ, Feder M, Grosjean H, Bujnicki JM

MODOMICS: a database of RNA modification pathways.

Nucleic Acids Res

Kudla G, Lipinski L, Caffin F, Helwak A, Zylicz M

High guanine and cytosine content increases mRNA levels in mammalian cells

PLoS Biol

Galazka G, Stasiolek M, Walczak A, Jurewicz A, Zylicz A, Brosnan CF, Raine CS, Selmaj KW

Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis.

J Immunol

Bieganowski P, Seidle HF, Wojcik M, Brenner C

Synthetic lethal and biochemical analyses of NAD and NADH kinases in Saccharomyces cerevisiae establish separation of cellular functions.

J Biol Chem

Wojcik M, Seidle HF, Bieganowski P, Brenner C

Glutamine-dependent NAD+ synthetase. How a two-domain, three-substrate enzyme avoids waste.

J Biol Chem

Kudla G, Lipinski L, Caffin F, Helwak A, Zylicz M

High guanine and cytosine content increases mRNA levels in mammalian cells

PLoS Biol

Galazka G, Stasiolek M, Walczak A, Jurewicz A, Zylicz A, Brosnan CF, Raine CS, Selmaj KW

Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis.

J Immunol

2005

Jólkowska J, Pieczonka A, Strabel T, Boruczkowski D, Wachowiak J, Bader P, Witt M

Hematopoietic chimerism after allogeneic stem cell transplantation: a comparison of quantitative analysis by automated DNA sizing and fluorescent in situ hybridization

BMC Blood Disord

Broczek KM, Pawlińska-Chmara R, Kupisz-Urbańska M, Mossakowska M

Anthropometric chest structure of Polish centenarians

J Physiol Pharmacol

Filipek S

Organization of rhodopsin molecules in native membranes of rod cells--an old theoretical model compared to new experimental data.

J Mol Model

Filipek S, Modzelewska A, Krzysko KA

Functional oligomers of rhodopsin – a G protein-coupled receptor template

Joint Meeting on Medical Chemistry

Sokal I, Dupps WJ, Grassi MA, Brown J Jr, Affatigato LM, Roychowdhury N, Yang L, Filipek S, Palczewski K, Stone EM, Baehr W

A novel GCAP1 missense mutation (L151F) in a large family with autosomal dominant cone-rod dystrophy (adCORD)

Invest Ophthalmol Vis Sci

Bernstein HG, Blazejczyk M, Rudka T, Gundelfinger ED, Dobrowolny H, Bogerts B, Kreutz MR, Kuznicki J, Wojda U

The Alzheimer disease-related calcium-binding protein Calmyrin is present in human forebrain with an altered distribution in Alzheimer's as compared to normal ageing brains

Neuropathol Appl Neurobiol

Bhattacharya S, Lee YT, Michowski W, Jastrzebska B, Filipek A, Kuznicki J, Chazin WJ

The modular structure of SIP facilitates its role in stabilizing multiprotein assemblies

Biochemistry

Leśniak W, Szczepańska A, Kuźnicki J

Calcyclin (S100A6) expression is stimulated by agents evoking oxidative stress via the antioxidant response element.

Biochim Biophys Acta

Palczewska M, Batta G, Groves P, Linse S, Kuznicki J

Characterization of calretinin I-II as an EF-hand, Ca2+, H+-sensing domain

Protein Sci

Puzianowska-Kuznicka M, Kuznicki J

Genetic alterations in accelerated ageing syndromes. Do they play a role in natural ageing?

Int J Biochem Cell Biol

Sobczak A, Blazejczyk M, Piszczek G, Zhao G, Kuznicki J, Wojda U

Calcium-binding calmyrin forms stable covalent dimers in vitro, but in vivo is found in monomeric form.

Acta Biochim Pol

Zekanowski C, Religa D, Safranow K, Maruszak A, Dziedziejko V, Styczyńska M, Gacia M, Golan M, Pepłońska B, Chlubek D, Kuźnicki J, Barcikowska M

The -22c/t polymorphism in presenilin 1 gene is not connected with late-onset and early-onset familial Alzheimer's disease in Poland

J Neural Transm

Azim MK, Goehring W, Song HK, Ramachandran R, Bochtler M, Goettig P

Characterization of the HslU chaperone affinity for HslV protease

Protein Sci

Dandanell G,Szczepanowski RH, Kierdaszuk B, Shugar D, Bochtler M

Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene

J Mol Biol

Filipek R, Potempa J, Bochtler M

A comparison of staphostatin B with standard mechanism serine protease inhibitors

J Biol Chem

Firczuk M, Mucha A, Bochtler M

Crystal structures of active LytM

J Mol Biol

Grazulis S, Manakova E, Roessle M, Bochtler M, Tamulaitiene G, Huber R, Siksnys V

Structure of the metal-independent restriction enzyme BfiI reveals fusion of a specific DNA-binding domain with a nonspecific nuclease.

Proc Natl Acad Sci U S A

Groll M, Bochtler M, Brandstetter H, Clausen T, Huber R

Molecular machines for protein degradation.

Chembiochem

Korza HJ, Bochtler M

Pseudomonas aeruginosa LD-carboxypeptidase, a serine peptidase with a Ser-His-Glu triad and a nucleophilic elbow.

J Biol Chem

Odintsov SG, Sabała I, Bourenkov G, Rybin V, Bochtler M

Staphylococcus aureus aminopeptidase S is a founding member of a new peptidase clan

J Biol Chem

Odintsov SG, Sabała I, Bourenkov G, Rybin V, Bochtler M

Substrate access to the active sites in aminopeptidase T, a representative of a new metallopeptidase clan.

J Mol Biol

Szczepanowski RH, Filipek R, Bochtler M

Crystal structure of a fragment of mouse ubiquitin-activating enzyme.

J Biol Chem

Potempa J, Golonka E, Filipek R, Shaw LN

Fighting an enemy within: cytoplasmic inhibitors of bacterial cysteine proteases

Mol Microbiol

Marcyjaniak M, Odintsov SG, Sabala I, Bochtler M

Peptydoglycan amidase MepA is a LAS metallopeptidase

J Biol Chem

Radlińska M, Piekarowicz A, Galimand M, Bujnicki JM

Cloning and preliminary characterization of a GATC-specific beta2-class DNA:m6A methyltransferase encoded by transposon Tn1549 from Enterococcus spp.

Pol J Microbiol

Radlinska M, Kondrzycka-Dada A, Piekarowicz A, Bujnicki JM

Identification of amino acids important for target recognition by the DNA:m5C methyltransferase M.NgoPII by alanine-scanning mutagenesis of residues at the protein-DNA interface.

Proteins

Raczko AM, Bujnicki JM, Pawlowski M, Godlewska R, Lewandowska M, Jagusztyn-Krynicka EK

Characterization of new DsbB-like thiol-oxidoreductases of Campylobacter jejuni and Helicobacter pylori and classification of the DsbB family based on phylogenomic, structural and functional criteria.

Microbiology

Purushothaman SK, Bujnicki JM, Grosjean H, Lapeyre B

Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA.

Mol Cell Biol

Kosinski J, Steindorf I, Bujnicki JM, Giron-Monzon L, Friedhoff P

Analysis of the quaternary structure of the MutL C-terminal domain.

J Mol Biol

Kosinski J, Gajda MJ, Cymerman IA, Kurowski MA, Pawlowski M, Boniecki M, Obarska A, Papaj G, Sroczynska-Obuchowicz P, Tkaczuk KL, Sniezynska P, Sasin JM, Augustyn A, Bujnicki JM, Feder M

FRankenstein becomes a cyborg: the automatic recombination and realignment of fold recognition models in CASP6.

Proteins

Tkaczuk KL, Bujnicki JM, Bialkowska A, Bielecki S, Turkiewicz M, Cieslinski H, Kur J

Molecular modeling of a psychrophilic β-galactosidase

Biocatal Biotransform

Radlińska M, Piekarowicz A, Galimand M, Bujnicki JM

Cloning and preliminary characterization of a GATC-specific beta2-class DNA:m6A methyltransferase encoded by transposon Tn1549 from Enterococcus spp.

Pol J Microbiol

Radlinska M, Kondrzycka-Dada A, Piekarowicz A, Bujnicki JM

Identification of amino acids important for target recognition by the DNA:m5C methyltransferase M.NgoPII by alanine-scanning mutagenesis of residues at the protein-DNA interface.

Proteins

Raczko AM, Bujnicki JM, Pawlowski M, Godlewska R, Lewandowska M, Jagusztyn-Krynicka EK

Characterization of new DsbB-like thiol-oxidoreductases of Campylobacter jejuni and Helicobacter pylori and classification of the DsbB family based on phylogenomic, structural and functional criteria.

Microbiology

Purta E, van Vliet F, Tricot C, De Bie LG, Feder M, Skowronek K, Droogmans L, Bujnicki JM

Sequence-structure-function relationships of a tRNA (m7G46) methyltransferase studied by homology modeling and site-directed mutagenesis.

Proteins

Purushothaman SK, Bujnicki JM, Grosjean H, Lapeyre B

Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA.

Mol Cell Biol

Pingoud V, Sudina A, Geyer H, Bujnicki JM, Lurz R, Lüder G, Morgan R, Kubareva E, Pingoud A

Specificity changes in the evolution of type II restriction endonucleases: a biochemical and bioinformatic analysis of restriction enzymes that recognize unrelated sequences

J Biol Chem

Pingoud V, Geyer H, Geyer R, Kubareva E, Bujnicki JM, Pingoud A

Identification of base-specific contacts in protein-DNA complexes by photocrosslinking and mass spectrometry: a case study using the restriction endonuclease SsoII

Mol Biosyst

Pawlak SD, Radlinska M, Chmiel AA, Bujnicki JM, Skowronek KJ

Inference of relationships in the 'twilight zone' of homology using a combination of bioinformatics and site-directed mutagenesis: a case study of restriction endonucleases Bsp6I and PvuII

Nucleic Acids Res

Kosinski J, Steindorf I, Bujnicki JM, Giron-Monzon L, Friedhoff P

Analysis of the quaternary structure of the MutL C-terminal domain.

J Mol Biol

Kosinski J, Feder M, Bujnicki JM

The PD-(D/E)XK superfamily revisited: identification of new members among proteins involved in DNA metabolism and functional predictions for domains of (hitherto) unknown function.

BMC Bioinformatics

Koliński A, Bujnicki JM

Generalized protein structure prediction based on combination of fold-recognition with de novo folding and evaluation of models.

Proteins

Ishikawa K, Watanabe M, Kuroita T, Uchiyama I, Bujnicki JM, Kawakami B, Tanokura M, Kobayashi I

Discovery of a novel restriction endonuclease by genome comparison and application of a wheat-germ-based cell-free translation assay: PabI (5'-GTA/C) from the hyperthermophilic archaeon Pyrococcus abyssi

Nucleic Acids Res

Feder M, Bujnicki JM

Identification of a new family of putative PD-(D/E)XK nucleases with unusual phylogenomic distribution and a new type of the active site.

BMC Genomics

Cymerman IA, Meiss G, Bujnicki JM

DNase II is a member of the phospholipase D superfamily.

Bioinformatics

Chmiel AA, Radlinska M, Pawlak SD, Krowarsch D, Bujnicki JM, Skowronek KJ

A theoretical model of restriction endonuclease NlaIV in complex with DNA, predicted by fold recognition and validated by site-directed mutagenesis and circular dichroism spectroscopy.

Protein Eng Des Sel

Chmiel AA, Bujnicki JM, Skowronek KJ

A homology model of restriction endonuclease SfiI in complex with DNA

BMC Struct Biol

Bujnicki J.M.

Przewidywanie struktury bialek: Boltzmann i Darwin

Kosmos

Armalyte E, Bujnicki JM, Giedriene J, Gasiunas G, Kosiński J, Lubys A

Mva1269I: a monomeric type IIS restriction endonuclease from Micrococcus varians with two EcoRI- and FokI-like catalytic domains.

J Biol Chem

Klejman MP, Zhao X, van Schaik FM, Herr W, Timmers HT

Mutational analysis of BTAF1-TBP interaction: BTAF1 can rescue DNA-binding defective TBP mutants.

Nucleic Acids Res

Ilyushik E, Pryce DW, Walerych D, Riddell T, Wakeman JA, McInerny CJ, McFarlane RJ

Psc3 cohesin of Schizosaccharomyces pombe: cell cycle analysis and identification of three distinct isoforms.

Biol Chem

Bucko-Justyna M, Lipinski L, Burgering BM, Trzeciak L

Characterization of testis-specific serine-threonine kinase 3 and its activation by phosphoinositide-dependent kinase-1-dependent signalling.

FEBS J

2004

Geremek M, Witt M

Primary ciliary dyskinesia: genes, candidate genes and chromosomal regions

J Appl Genet

Krawczyński MR, Dmeńska H, Witt M

Apparent X-linked primary ciliary dyskinesia associated with retinitis pigmentosa and a hearing loss

J Appl Genet

Krawczyński MR, Witt M

PCD and RP: X-linked inheritance of both disorders?

Pediatr Pulmonol

Lubka M, Wojda A, Witt M

Mikrojądra w komórkach człowieka - powstawanie, zawartość oraz wykorzystanie diagnostyczne i prognostyczne

Postępy Biol Kom

Wieczorowska-Tobis K, Niemir ZI, Guzik P, Mossakowska M

Kidney function estimated with different formulas in centenarians

Rocz Akad Med Bialymst

Zyczkowska J, Klich-Raczka A, Mossakowska M, Gasowski J, Wieczorowska-Tobis K, Grodzicki T

Blood pressure in centenarians in Poland

J Hum Hypertens

Filipek S, Krzysko KA , Fotiadis D, Liang Y, Saperstein DA, Engel A, Palczewski K

A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface

Photochem Photobiol Sci

Fotiadis D, Liang Y, Filipek S, Saperstein DA, Engel A, Palczewski K

The G protein-coupled receptor rhodopsin in the native membrane

FEBS Lett

Imanishi Y, Yang L, Sokal I, Filipek S, Palczewski K, Baehr W

Diversity of guanylate cyclase-activating proteins (GCAPs) in teleost fish: characterization of three novel GCAPs (GCAP4, GCAP5, GCAP7) from zebrafish (Danio rerio) and prediction of eight GCAPs (GCAP1-8) in pufferfish (

J Mol Evol

Jastrzebska B, Maeda T, Zhu L, Fotiadis D, Filipek S, Engel A, Stenkamp RE, Palczewski K

Functional characterization of rhodopsin monomers and dimers in detergents

J Biol Chem

Liang Y, Fotiadis D, Maeda T, Maeda A, Modzelewska A, Filipek S, Saperstein DA, Engel A, Palczewski K

Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice

J Biol Chem

Park PS, Filipek S, Wells JW, Palczewski K

Oligomerization of G protein-coupled receptors: past, present, and future.

Biochemistry

Suda K, Filipek S, Palczewski K, Engel A, Fotiadis D

The supramolecular structure of the GPCR rhodopsin in solution and native disc membranes.

Mol Membr Biol

Zhu L, Jang GF, Jastrzebska B, Filipek S, Pearce-Kelling SE, Aguirre GD, Stenkamp RE, Acland GM, Palczewski K

A naturally occurring mutation of the opsin gene (T4R) in dogs affects glycosylation and stability of the G protein-coupled receptor.

J Biol Chem

Billing-Marczak K, Ziemińska E, Leśniak W, Łazarewicz JW, Kuźnicki J

Calretinin gene promoter activity is differently regulated in neurons and cancer cells. Role of AP2-like cis element and zinc ions

Biochim Biophys Acta

Lee YT, Jacob J, Michowski W, Nowotny M, Kuznicki J, Chazin WJ

Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain.

J Biol Chem

Wojda U

Gene therapy of hematopoietic cells: development of strategies and vectors. (in Polish)

Postepy Biol Kom

Zekanowski C, Pepłońska B, Styczyńska M, Religa D, Pfeffer A, Czyzewski K, Gabryelewicz T, Szybińska A, Kijanowska-Haładyna B, Kotapka-Minc S, Łuczywek E, Barczak A, Wasiak B, Chodakowska-Zebrowska M, Przekop I, Kuźnicki J, Barcikowska M

The E318G substitution in PSEN1 gene is not connected with Alzheimer's disease in a large Polish cohort.

Neurosci Lett

Zekanowski C, Religa D, Graff C, Filipek S, Kuźnicki J

Genetic aspects of Alzheimer's disease

Acta Neurobiol Exp (Wars)

Brzezińska A, Magalska A, Szybińska A, Sikora E

Proliferation and apoptosis of human CD8(+)CD28(+) and CD8(+)CD28(-) lymphocytes during aging

Exp Gerontol

Marcyjaniak M, Odintsov SG, Sabala I, Bochtler M

Peptidoglycan amidase MepA is a LAS metallopeptidase.

J Biol Chem

Bochtler M, Odintsov SG, Marcyjaniak M, Sabala I

Similar active sites in lysostaphins and D-Ala-D-Ala metallopeptidases.

Protein Sci

Filipek R, Szczepanowski R, Sabat A, Potempa J, Bochtler M

Prostaphopain B structure: a comparison of proregion-mediated and staphostatin-mediated protease inhibition

Biochemistry

Marcyjaniak M, Odintsov SG, Sabala I, Bochtler M

Peptidoglycan amidase MepA is a LAS metallopeptidase

J Biol Chem

Odintsov SG, Sabala I, Marcyjaniak M, Bochtler M

Latent LytM at 1.3A resolution

J Mol Biol

Golonka E, Filipek R, Sabat A, Sinczak A, Potempa J

Genetic characterization of staphopain genes in Staphylococcus aureus

Biol Chem

Ye X, O\'Neil PK, Foster AN, Gajda MJ, Kosinski J, Kurowski MA, Bujnicki JM, Friedman AM, Bailey-Kellogg C

Probabilistic cross-link analysis and experiment planning for high-throughput elucidation of protein structure.

Protein Sci

Schäfer P, Scholz SR, Gimadutdinow O, Cymerman IA, Bujnicki JM, Ruiz-Carrillo A, Pingoud A, Meiss G

Structural and functional characterization of mitochondrial EndoG, a sugar non-specific nuclease which plays an important role during apoptosis.

J Mol Biol

Sasin JM, Bujnicki JM

COLORADO3D, a web server for the visual analysis of protein structures.

Nucleic Acids Res

Saravanan M, Bujnicki JM, Cymerman IA, Rao DN, Nagaraja V

Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily.

Nucleic Acids Res

Roovers M, Wouters J, Bujnicki JM, Tricot C, Stalon V, Grosjean H, Droogmans L

A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase

Nucleic Acids Res

Potluri S, Khan AA, Kuzminykh A, Bujnicki JM, Friedman AM, Bailey-Kellogg C

Geometric analysis of cross-linkability for protein fold discrimination.

Pac Symp Biocomput

Paziewska A, Wyrwicz LS, Bujnicki JM, Bomsztyk K, Ostrowski J

Cooperative binding of the hnRNP K three KH domains to mRNA targets.

FEBS Lett

Nes WD, Jayasimha P, Zhou W, Kanagasabai R, Jin C, Jaradat TT, Shaw RW, Bujnicki JM

Sterol methyltransferase: functional analysis of highly conserved residues by site-directed mutagenesis.

Biochemistry

Maravić G, Bujnicki JM, Flögel M

Mutational analysis of basic residues in the N-terminus of the rRNA:m6A methyltransferase ErmC'

Folia Microbiol (Praha)

Koudan EV, Bujnicki JM, Gromova ES

Homology modeling of the CG-specific DNA methyltransferase SssI and its complexes with DNA and AdoHcy.

J Biomol Struct Dyn

Bujnicki JM, Oudjama Y, Roovers M, Owczarek S, Caillet J, Droogmans L

Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA.

RNA

Bujnicki JM, Feder M, Ayres CL, Redman KL

Sequence-structure-function studies of tRNA:m5C methyltransferase Trm4p and its relationship to DNA:m5C and RNA:m5U methyltransferases.

Nucleic Acids Res

Armengaud J, Urbonavicius J, Fernandez B, Chaussinand G, Bujnicki JM, Grosjean H

N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.

J Biol Chem

Koudan EV, Bujnicki JM, Gromova ES

Homology modeling of the CG-specific DNA methyltransferase SssI and its complexes with DNA and AdoHcy.

J Biomol Struct Dyn

Bujnicki JM, Oudjama Y, Roovers M, Owczarek S, Caillet J, Droogmans L

Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA.

RNA

Bujnicki JM, Feder M, Ayres CL, Redman KL

Sequence-structure-function studies of tRNA:m5C methyltransferase Trm4p and its relationship to DNA:m5C and RNA:m5U methyltransferases.

Nucleic Acids Res

Armengaud J, Urbonavicius J, Fernandez B, Chaussinand G, Bujnicki JM, Grosjean H

N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.

J Biol Chem

Mycko MP, Cwiklinska H, Szymanski J, Szymanska B, Kudla G, Kilianek L, Odyniec A, Brosnan CF, Selmaj KW

Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II.

J Immunol

Walerych D, Kudla G, Gutkowska M, Wawrzynow B, Muller L, King FW, Helwak A, Boros J, Zylicz A, Zylicz M

Hsp90 chaperones wild-type p53 tumor suppressor protein.

J Biol Chem

Jassem J, Jassem E, Jakóbkiewicz-Banecka J, Rzyman W, Badzio A, Dziadziuszko R, Kobierska-Gulida G, Szymanowska A, Skrzypski M, Zylicz M

P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma.

Cancer

Dworakowska D, Jassem E, Jassem J, Peters B, Dziadziuszko R, Zylicz M, Jakóbkiewicz-Banecka J, Kobierska-Gulida G, Szymanowska A, Skokowski J, Roessner A, Schneider-Stock R

MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC).

Lung Cancer

Mycko MP, Cwiklinska H, Szymanski J, Szymanska B, Kudla G, Kilianek L, Odyniec A, Brosnan CF, Selmaj KW

Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II.

J Immunol

Kudla G, Helwak A, Lipinski L

Gene conversion and GC-content evolution in mammalian Hsp70.

Mol Biol Evol

Walerych D, Kudla G, Gutkowska M, Wawrzynow B, Muller L, King FW, Helwak A, Boros J, Zylicz A, Zylicz M

Hsp90 chaperones wild-type p53 tumor suppressor protein.

J Biol Chem

Müller L, Schaupp A, Walerych D, Wegele H, Buchner J

Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures.

J Biol Chem

Jassem J, Jassem E, Jakóbkiewicz-Banecka J, Rzyman W, Badzio A, Dziadziuszko R, Kobierska-Gulida G, Szymanowska A, Skrzypski M, Zylicz M

P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma.

Cancer

Dworakowska D, Jassem E, Jassem J, Peters B, Dziadziuszko R, Zylicz M, Jakóbkiewicz-Banecka J, Kobierska-Gulida G, Szymanowska A, Skokowski J, Roessner A, Schneider-Stock R

MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC).

Lung Cancer

Lee YT, Jacob J, Michowski W, Nowotny M, Kuznicki J, Chazin WJ

Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain.

J Biol Chem

2003

Pruszynski J, Gross R, Mossakowska M, Barcikowska M, Czyzewski K, Derejczyk J, Galus K, Grodzicki T, Jedrkiewicz H, Klich-Raczka A, Kupsc W, Luczywek E, Pfeffer A, Puzianowska-Kuznicka M, Sosnowski M, Styczynska M, Wasiak B, Wieczorowska-Tobis K, Zyczkows

Functioning of Polish centenarians

Gerontologia

Wojda A, Witt M

Manifestations of ageing at the cytogenetic level

J Appl Genet

Wojda A, Wolnik-Brzozowska D, Lubka M, Mossakowska M, Witt M

The 102-year old woman with translocation (7;12) and infertility in anamnesis

J Appl Genet

Zyczkowska J, Klich-Raczka A, Wizner B, Mossakowska M, Wieczorowska-Tobis K, Grodzicki T

Hypertension and cognitive and functional performance in centenarians

New Medicine

Majka L, Goździk J, Witt M

Cystic fibrosis--a probable cause of Frédéric Chopin's suffering and death

J Appl Genet

Filipek S, Teller DC, Palczewski K, Stenkamp R

The crystallographic model of rhodopsin and its use in studies of other G protein-coupled receptors.

Annu Rev Biophys Biomol Struct

Fotiadis D, Liang Y, Filipek S, Saperstein DA, Engel A, Palczewski K

Atomic-force microscopy: Rhodopsin dimers in native disc membranes

Nature

Fritze O, Filipek S, Kuksa V, Palczewski K, Hofmann KP, Ernst OP

Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation.

Proc Natl Acad Sci U S A

Liang Y, Fotiadis D, Filipek S, Saperstein DA, Palczewski K, Engel A

Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes.

J Biol Chem

Liang Y, Fotiadis D, Filipek S, Saperstein DA, Palczewski K, Engel A

Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes

J Biol Chem

Maeda T, Van Hooser JP, Driessen CA, Filipek S, Janssen JJ, Palczewski K

Evaluation of the role of the retinal G protein-coupled receptor (RGR) in the vertebrate retina in vivo.

J Neurochem

Mirzadegan T, Benkö G, Filipek S, Palczewski K

Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin.

Biochemistry

Noorwez SM, Kuksa V, Imanishi Y, Zhu L, Filipek S, Palczewski K, Kaushal S

Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosa.

J Biol Chem

Schadel SA, Heck M, Maretzki D, Filipek S, Teller DC, Palczewski K, Hofmann KP

Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin.

J Biol Chem

Nowotny M, Spiechowicz M, Jastrzebska B, Filipek A, Kitagawa K, Kuznicki J

Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins

J Biol Chem

Palczewska M, Groves P, Batta G, Heise B, Kuźnicki J

Calretinin and calbindin D28k have different domain organizations

Protein Sci

Pepłońska B, Zekanowski C, Religa D, Czyzewski K, Styczyńska M, Pfeffer A, Gabryelewicz T, Gołebiowski M, Luczywek E, Wasiak B, Barczak A, Chodakowska M, Barcikowska M, Kuźnicki J

Strong association between Saitohin gene polymorphism and tau haplotype in the Polish population

Neurosci Lett

Zekanowski C, Styczyńska M, Pepłońska B, Gabryelewicz T, Religa D, Ilkowski J, Kijanowska-Haładyna B, Kotapka-Minc S, Mikkelsen S, Pfeffer A, Barczak A, Łuczywek E, Wasiak B, Chodakowska-Zebrowska M, Gustaw K, Łaczkowski J, Sobów T, Kuźnicki J, Barcikowsk

Mutations in presenilin 1, presenilin 2 and amyloid precursor protein genes in patients with early-onset Alzheimer's disease in Poland

Exp Neurol

Zekanowski C, Pepłońska B, Styczyńska M, Gustaw K, Kuźnicki J, Barcikowska M

Mutation screening of the MAPT and STH genes in Polish patients with clinically diagnosed frontotemporal dementia

Dement Geriatr Cogn Disord

Zekanowski C, Przyluska-Fiszer A, Barcikowska M

Alzheimer's disease: between diagnostic, economy and ethic (in Polish)

Choroby otępienne. Teoria i praktyka

Tighe O, Dunican D, O'Neill C, Bertorelle G, Beattie D, Graham C, Zschocke J, Cali F, Romano V, Hrabincova E, Kozak L, Nechyporenko M, Livshits L, Guldberg P, Jurkowska M, Zekanowski C, Perez B, Desviat LR, Ugarte M, Kucinskas V, Knappskog P, Treacy E, N

Genetic diversity within the R408W phenylketonuria mutation lineages in Europe

Hum Mutat

Zekanowski C

The sun, the genome, the internet… eugenics?

Gemellological Rev

Zekanowski C

Molecular diagnostics of Alzheimer's disease (in Polish)

Medycyna ogólna

Dubin G, Krajewski M, Popowicz G, Stec-Niemczyk J, Bochtler M, Potempa J, Dubin A, Holak TA

A novel class of cysteine protease inhibitors: solution structure of staphostatin A from Staphylococcus aureus.

Biochemistry

Filipek R, Rzychon M, Oleksy A, Gruca M, Dubin A, Potempa J, Bochtler M

The Staphostatin-staphopain complex: a forward binding inhibitor in complex with its target cysteine protease.

J Biol Chem

Rzychon M, Filipek R, Sabat A, Kosowska K, Dubin A, Potempa J, Bochtler M

Staphostatins resemble lipocalins, not cystatins in fold

Protein Sci

Scholz SR, Korn C, Bujnicki JM, Gimadutdinow O, Pingoud A, Meiss G

Experimental evidence for a beta beta alpha-Me-finger nuclease motif to represent the active site of the caspase-activated DNase.

Biochemistry

Sasin JM, Kurowski MA, Bujnicki JM

STRUCLA: a WWW meta-server for protein structure comparison and evolutionary classification.

Bioinformatics

Pingoud V, Conzelmann C, Kinzebach S, Sudina A, Metelev V, Kubareva E, Bujnicki JM, Lurz R, Lüder G, Xu SY, Pingoud A

PspGI, a type II restriction endonuclease from the extreme thermophile Pyrococcus sp.: structural and functional studies to investigate an evolutionary relationship with several mesophilic restriction enzymes

J Mol Biol

Mouaikel J, Bujnicki JM, Tazi J, Bordonné R

Sequence-structure-function relationships of Tgs1, the yeast snRNA/snoRNA cap hypermethylase

Nucleic Acids Res

Maravić G, Feder M, Pongor S, Flögel M, Bujnicki JM

Mutational analysis defines the roles of conserved amino acid residues in the predicted catalytic pocket of the rRNA:m6A methyltransferase ErmC'

J Mol Biol

Maravić G, Bujnicki JM, Feder M, Pongor S, Flögel M

Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions

Nucleic Acids Res

Kurowski MA, Sasin JM, Feder M, Debski J, Bujnicki JM

Characterization of the cofactor-binding site in the SPOUT-fold methyltransferases by computational docking of S-adenosylmethionine to three crystal structures.

BMC Bioinformatics

Kurowski MA, Bujnicki JM

GeneSilico protein structure prediction meta-server.

Nucleic Acids Res

Kurowski MA, Bhagwat AS, Papaj G, Bujnicki JM

Phylogenomic identification of five new human homologs of the DNA repair enzyme AlkB.

BMC Genomics

Kosinski J, Cymerman IA, Feder M, Kurowski MA, Sasin JM, Bujnicki JM

A "FRankenstein's monster" approach to comparative modeling: merging the finest fragments of Fold-Recognition models and iterative model refinement aided by 3D structure evaluation

Proteins

Gordon RK, Ginalski K, Rudnicki WR, Rychlewski L, Pankaskie MC, Bujnicki JM, Chiang PK

Anti-HIV-1 activity of 3-deaza-adenosine analogs. Inhibition of S-adenosylhomocysteine hydrolase and nucleotide congeners.

Eur J Biochem

Feder M, Pas J, Wyrwicz LS, Bujnicki JM

Molecular phylogenetics of the RrmJ/fibrillarin superfamily of ribose 2'-O-methyltransferases

Gene

Droogmans L, Roovers M, Bujnicki JM, Tricot C, Hartsch T, Stalon V, Grosjean H

Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures.

Nucleic Acids Res

De Bie LG, Roovers M, Oudjama Y, Wattiez R, Tricot C, Stalon V, Droogmans L, Bujnicki JM

The yggH gene of Escherichia coli encodes a tRNA (m7G46) methyltransferase.

J Bacteriol

Bujnicki JM, Prigge ST, Caridha D, Chiang PK

Structure, evolution, and inhibitor interaction of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.

Proteins

Bujnicki JM, Albert MA, Nelson DJ, Thurlow DL

Fold recognition, homology modeling, docking simulations, kinetics analysis and mutagenesis of ATP/CTP:tRNA nucleotidyltransferase from Methanococcus jannaschii.

Proteins

Bujnicki JM

Crystallographic and bioinformatic studies on restriction endonucleases: inference of evolutionary relationships in the "midnight zone" of homology

Curr Protein Pept Sci

Coker JA, Sheridan PP, Loveland-Curtze J, Gutshall KR, Auman AJ, Brenchley JE

Biochemical characterization of a beta-galactosidase with a low temperature optimum obtained from an Antarctic arthrobacter isolate.

J Bacteriol

Coker JA, Sheridan PP, Loveland-Curtze J, Gutshall KR, Auman AJ, Brenchley JE

Biochemical characterization of a beta-galactosidase with a low temperature optimum obtained from an Antarctic arthrobacter isolate.

J Bacteriol

Nowotny M, Spiechowicz M, Jastrzebska B, Filipek A, Kitagawa K, Kuznicki J

Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins

J Biol Chem.

2002

Wieczorowska-Tobis K, Mossakowska M, Niemir Z, Breborowicz A, Oreopoulos DG

Discrepancies in creatinine clearance in centenarians when calculated by two different mathematical formulas

Nephrol Dial Transplant

Wieczorowska-Tobis K, Niemir Z, Mossakowska M, Klich-Raczka A, Zyczkowska J

Anemia in centenarians

J Am Geriatr Soc

Billing-Marczak K, Buzanska L, Winsky L, Nowotny M, Rudka T, Isaacs K, Belin MF, Kuznicki J

AP2-like cis element is required for calretinin gene promoter activity in cells of neuronal phenotype differentiated from multipotent human cell line DEV.

Biochim Biophys Acta

Kuksa V, Bartl F, Maeda T, Jang GF, Ritter E, Heck M, Van Hooser JP, Liang Y, Filipek S, Gelb MH, Hofmann KP, Palczewski K

Biochemical and physiological properties of rhodopsin regenerated with 11-cis-6-ring- and 7-ring-retinals.

J Biol Chem

Billing-Marczak K, Buzanska L, Winsky L, Nowotny M, Rudka T, Isaacs K, Belin MF, Kuznicki J

AP2-like cis element is required for calretinin gene promoter activity in cells of neuronal phenotype differentiated from multipotent human cell line DEV

Biochim Biophys Acta

Filipek A, Jastrzebska B, Nowotny M, Kuznicki J

CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family

J Biol Chem

Filipek A, Jastrzebska B, Nowotny M, Kwiatkowska K, Hetman M, Surmacz L, Wyroba E,Kuznicki J

Ca2+-dependent translocation of the calcyclin-binding protein in neurons and neuroblastoma NB-2a cells

J Biol Chem

Cabalska B, Nowacka M, Nowaczewska I, Zekanowski C, Zorska K

Atypical PKU - treatment effectiveness

Medycyna Wieku Rozwojowego VI

Zekanowski C, Gizewska M, Nowacka M, Cabalska B

Novel PKU treatment methods

Medycyna Wieku Rozwojowego

Zekanowski C

Genetic aspects of Alzheimer’s disease

Medycyna Ogólna

Ramachandran R, Hartmann C, Song HK, Huber R, Bochtler M

Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY)

Proc Natl Acad Sci U S A

Zhang P, Nicholson DE, Bujnicki JM, Su X, Brendle JJ, Ferdig M, Kyle DE, Milhous WK, Chiang PK

Angiogenesis inhibitors specific for methionine aminopeptidase 2 as drugs for malaria and leishmaniasis

J Biomed Sci

Xu Y, Keene DR, Bujnicki JM, Höök M, Lukomski S

Streptococcal Scl1 and Scl2 proteins form collagen-like triple helices.

J Biol Chem

Pintard L, Lecointe F, Bujnicki JM, Bonnerot C, Grosjean H, Lapeyre B

Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop

EMBO J

Pintard L, Bujnicki JM, Lapeyre B, Bonnerot C

MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase

EMBO J

Pingoud V, Kubareva E, Stengel G, Friedhoff P, Bujnicki JM, Urbanke C, Sudina A, Pingoud A

Evolutionary relationship between different subgroups of restriction endonucleases.

J Biol Chem

Godlewska R, Bujnicki JM, Ostrowski J, Jagusztyn-Krynicka EK

The hppA gene of Helicobacter pylori encodes the class C acid phosphatase precursor

FEBS Lett

Bujnicki J, Rychlewski L, Fischer D

Fold-recognition detects an error in the Protein Data Bank

Bioinformatics

Bujnicki JM, Rychlewski L

In silico identification, structure prediction and phylogenetic analysis of the 2'-O-ribose (cap 1) methyltransferase domain in the large structural protein of ssRNA negative-strand viruses

Protein Eng

Bujnicki JM, Rychlewski L

RNA:(guanine-N2) methyltransferases RsmC/RsmD and their homologs revisited--bioinformatic analysis and prediction of the active site based on the uncharacterized Mj0882 protein structure

BMC Bioinformatics

Bujnicki JM, Rychlewski L

Fold-recognition analysis predicts that the Tag protein family shares a common domain with the helix-hairpin-helix DNA glycosylases

DNA Repair (Amst)

Bujnicki JM, Leach RA, Debski J, Rychlewski L

Bioinformatic analyses of the tRNA: (guanine 26, N2,N2)-dimethyltransferase (Trm1) family

J Mol Microbiol Biotechnol

Bujnicki JM, Feder M, Rychlewski L, Fischer D

Errors in the D. radiodurans large ribosomal subunit structure detected by protein fold-recognition and structure validation tools

FEBS Lett

Bujnicki JM, Feder M, Radlinska M, Blumenthal RM

Structure prediction and phylogenetic analysis of a functionally diverse family of proteins homologous to the MT-A70 subunit of the human mRNA:m(6)A methyltransferase

J Mol Evol

Bujnicki JM, Blumenthal RM, Rychlewski L

Sequence analysis and structure prediction of 23S rRNA:m1G methyltransferases reveals a conserved core augmented with a putative Zn-binding domain in the N-terminus and family-specific elaborations in the C-terminus

J Mol Microbiol Biotechnol

Bujnicki JM

Sequence permutations in the molecular evolution of DNA methyltransferases

BMC Evol Biol

Filipek A, Jastrzebska B, Nowotny M, Kwiatkowska K, Hetman M, Surmacz L, Wyroba E, Kuznicki J

Ca2+-dependent translocation of the calcyclin-binding protein in neurons and neuroblastoma NB-2a cells.

J Biol Chem

Filipek A, Jastrzebska B, Nowotny M, Kuznicki J

CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family

J Biol Chem

Billing-Marczak K, Buzanska L, Winsky L, Nowotny M, Rudka T, Isaacs K, Belin MF, Kuznicki J

AP2-like cis element is required for calretinin gene promoter activity in cells of neuronal phenotype differentiated from multipotent human cell line DEV.

Biochim Biophys Acta

2001

Wieczorowska-Tobis K, Mossakowska M, Niemir Z, Breborowicz A, Oreopoulos DG

Plasma creatine and sodium abnormalities in Polish centenarians

Ann Acad Med Gedan

Palczewska M, Groves P, Ambrus A, Kaleta A, Kövér KE, Batta G, Kuźnicki J

Structural and biochemical characterization of neuronal calretinin domain I-II (residues 1-100). Comparison to homologous calbindin D28k domain I-II (residues 1-93)

Eur J Biochem

Radlinska M, Bujnicki JM

Site-directed mutagenesis defines the catalytic aspartate in the active site of the atypical DNA: m4C methyltransferase M.NgoMXV

Acta Microbiol Pol

Radlinska M, Bujnicki JM

Cloning of enterohemorrhagic Escherichia coli phage VT-2 dam methyltransferase

Acta Microbiol Pol

Lundström J, Rychlewski L, Bujnicki J, Elofsson A

Pcons: a neural-network-based consensus predictor that improves fold recognition

Protein Sci

Bujnicki JM, Rychlewski L

The herpesvirus alkaline exonuclease belongs to the restriction endonuclease PD-(D/E)XK superfamily: insight from molecular modeling and phylogenetic analysis.

Virus Genes

Bujnicki JM, Rychlewski L

Grouping together highly diverged PD-(D/E)XK nucleases and identification of novel superfamily members using structure-guided alignment of sequence profiles.

J Mol Microbiol Biotechnol

Bujnicki JM, Rychlewski L

Reassignment of specificities of two cap methyltransferase domains in the reovirus lambda 2 protein

Genome Biol

Bujnicki JM, Rychlewski L

Unusual evolutionary history of the tRNA splicing endonuclease EndA: relationship to the LAGLIDADG and PD-(D/E)XK deoxyribonucleases.

Protein Sci

Bujnicki JM, Rychlewski L

Identification of a PD-(D/E)XK-like domain with a novel configuration of the endonuclease active site in the methyl-directed restriction enzyme Mrr and its homologs

Gene

Bujnicki JM, Rychlewski L

Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases

Acta Microbiol Pol

Bujnicki JM, Rotkiewicz P, Kolinski A, Rychlewski L

Three-dimensional modeling of the I-TevI homing endonuclease catalytic domain, a GIY-YIG superfamily member, using NMR restraints and Monte Carlo dynamics.

Protein Eng

Bujnicki JM, Radlinska M, Zaleski P, Piekarowicz A

Cloning of the Haemophilus influenzae Dam methyltransferase and analysis of its relationship to the Dam methyltransferase encoded by the HP1 phage

Acta Biochim Pol

Bujnicki JM, Radlinska M, Rychlewski L

Polyphyletic evolution of type II restriction enzymes revisited: two independent sources of second-hand folds revealed

Trends Biochem Sci

Bujnicki JM, Radlinska M

Cloning and characterization of M.LmoA118I, a novel DNA:m4C methyltransferase from the Listeria monocytogenes phage A118, a close homolog of M.NgoMXV

Acta Microbiol Pol

Bujnicki JM, Feder M, Radlinska M, Rychlewski L

mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships

BMC Bioinformatics

Bujnicki JM, Elofsson A, Fischer D, Rychlewski L

LiveBench-2: large-scale automated evaluation of protein structure prediction servers.

Proteins

Bujnicki JM, Elofsson A, Fischer D, Rychlewski L

LiveBench-1: continuous benchmarking of protein structure prediction servers

Protein Sci

Bujnicki JM, Elofsson A, Fischer D, Rychlewski L

Structure prediction meta server

Bioinformatics

Bujnicki JM

A model of structure and action of Sau3AI restriction endonuclease that comprises two MutH-like endonuclease domains within a single polypeptide.

Acta Microbiol Pol

Bujnicki JM

Understanding the evolution of restriction-modification systems: clues from sequence and structure comparisons.

Acta Biochim Pol

Bujnicki JM

In silico analysis of the tRNA:m1A58 methyltransferase family: homology-based fold prediction and identification of new members from Eubacteria and Archaea

FEBS Lett

Kaczanowski R, Trzeciak L, Kucharczyk K

Multitemperature single-strand conformation polymorphism.

Electrophoresis

Zylicz M, Wawrzynow A

Insights into the function of Hsp70 chaperones.

IUBMB Life

Zylicz M, King FW, Wawrzynow A

Hsp70 interactions with the p53 tumour suppressor protein

EMBO J

King FW, Wawrzynow A, Höhfeld J, Zylicz M

Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.

EMBO J

Jassem E, Nikliński J, Rosell R, Niklińska W, Jakóbkiewicz J, Monzo M, Chyczewski L, Kobierska G, Skokowski J, Zylicz M, Jassem J

Types and localisation of p53 gene mutations: a report on 332 non-small cell lung cancer patients.

Lung Cancer

Genevaux P, Wawrzynow A, Zylicz M, Georgopoulos C, Kelley WL

DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction.

J Biol Chem

Banecki B, Wawrzynow A, Puzewicz J, Georgopoulos C, Zylicz M

Structure-function analysis of the zinc-binding region of the Clpx molecular chaperone.

J Biol Chem

Kaczanowski R, Trzeciak L, Kucharczyk K

Multitemperature single-strand conformation polymorphism.

Electrophoresis

Zylicz M, Wawrzynow A

Insights into the function of Hsp70 chaperones.

IUBMB Life

Zylicz M, King FW, Wawrzynow A

Hsp70 interactions with the p53 tumour suppressor protein

EMBO J

King FW, Wawrzynow A, Höhfeld J, Zylicz M

Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.

EMBO J

Genevaux P, Wawrzynow A, Zylicz M, Georgopoulos C, Kelley WL

DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction.

J Biol Chem

Banecki B, Wawrzynow A, Puzewicz J, Georgopoulos C, Zylicz M

Structure-function analysis of the zinc-binding region of the Clpx molecular chaperone.

J Biol Chem

2000

Zekanowski C

Cloning - the crossroads of biology and culture

Gemellological Review

Mossakowska M, Puzianowska-Kuznicka M, Barcikowska M, Chiron-Jouan S, Czyzewski K, Derejczyk J, Franceschi C, Gabryelewicz T, Galus K, Grodzicki T, Gross R, Klich-Raczka A, Luczywek E, Passeri G, Pfeffer A, Pruszynski J, Radziszewska E, Sikora E, Sosnowski M, Styczynska M, Wasiak B, Wieczorowska-Tobis K, Zyczkowska J, Kuznicki J

Polish Centenarians Program “PolStu99” – search for longevity promoting factors (in Polish)

Gerontologia

Bujnicki JM, Rychlewski L

Prediction of a common fold for all four subunits of the yeast tRNA splicing endonuclease: implications for the evolution of the EndA/Sen family.

FEBS Lett

Bujnicki JM, Rychlewski L

Prediction of a novel RNA 2'-O-ribose methyltransferase subfamily encoded by the Escherichia coli YgdE open reading frame and its orthologs

Acta Microbiol Pol

Bujnicki JM, Radlinska M, Rychlewski L

Atomic model of the 5-methylcytosine-specific restriction enzyme McrA reveals an atypical zinc finger and structural similarity to betabetaalphaMe endonucleases

Mol Microbiol

Bujnicki JM

Sequence, structural, and evolutionary analysis of prokaryotic ribosomal protein L11 methyltransferases.

Acta Microbiol Pol

Bujnicki JM

Phylogenomic analysis of 16S rRNA:(guanine-N2) methyltransferases suggests new family members and reveals highly conserved motifs and a domain structure similar to other nucleic acid amino-methyltransferases.

FASEB J