It was the commissioned project of the Ministry of Science and Higher Education entitled: "Advanced molecular methods in haematology. Work out and implementation of standards of minimal residual disease, posttransplant chimerism and marker translocations analysis." The project with the overall budget of about 3 mln PLN linked elements of pediatric and adult molecular haematology related to basic research and practical applications. The consortium was composed of the major Polish centers of molecular haematology in Poznan, Warsaw, Cracow, Lublin and Zabrze what constituted the core of reference laboratories network active in this area in Poland. Haematological disorders selected for the study by the consortium were: pediatric acute lymphoblastic leukemia (ALL), pediatric and adult acute myeloid leukemia (AML), chronic myeloid leukemia (CML) and non-Hodgkin lymphomas (NHL); they were chosen as model disorders being already analysed on a molecular level in some of the Polish centers. A posttransplant chimerism and a minimal residual disease (MRD) were being analysed in connection to the disorders listed above. The project also aimed at constructing the database linking available clinical and molecular data of patients recruited to the program and also on establishing the multicenter collection of relevant biological material. The program was initiated at IIMCB and was being conducted by Prof. Michal Witt and coordinated by Dr. Malgorzata Mossakowska. The project resulted in two monographs:
Hematologia molekularna. Patogeneza, patomechanizmy i metody badawcze. Witt M, Szczepanski T, Dawidowska M (red.), OWN Poznan , 2009 (in Polish)
Molecular aspects of hematological malignancies. Laboratory problems from a clinical perspective. Eds. M Witt, M Dawidowska, T Szczepanski, Springer Verlag (in preparation)