Wsystkie publikacje

2023

Publikacja

Impaired iron recycling from erythrocytes is an early hallmark of aging.

Slusarczyk P, Mandal PK, Zurawska G, Niklewicz M, Chouhan K, Mahadeva R, Jończy A, Macias M, Szybinska A, Cybulska-Lubak M, Krawczyk O, Herman S, Mikula M, Serwa R, Lenartowicz M, Pokrzywa W, Mleczko-Sanecka K.

eLife. 2023

Preprint

Lysine-deficient proteome can be regulated through non-canonical ubiquitination and ubiquitin-independent proteasomal degradation.

Szulc NPiechota M, Thapa P, Pokrzywa W.

bioRxiv. 2023

Publikacja

xcore: an R package for inference of gene expression regulators.

Migdał M, Arakawa T, Takizawa S, Furuno M, Suzuki H, Arner E, Winata CL, Kaczkowski B.

BMC Bioinformatics.. 2023

Publikacja

The national burden of frailty and disproportionate distribution of its components-the predominance of slow gait speed: a 2018-19 face-to-face epidemiologic assessment representative of population of older Poles.

Piotrowicz K, Kujawska-Danecka H, Jagiełło K, Hajduk A, Skalska A, Mossakowska M, Zdrojewski T, Grodzicki T, Gąsowski J.

Aging Clin Exp Res.. 2023

Publikacja

Preparation of Caenorhabditis elegans for Scoring of Muscle-derived Exophers.

Banasiak K, Turek M, Pokrzywa W.

bio-protocol Journal. 2023

Publikacja

Clustered PHD domains in KMT2/MLL proteins are attracted by H3K4me3 and H3 acetylation-rich active promoters and enhancers.

Stroynowska-Czerwinska AM, Klimczak M, Pastor M, Kazrani AA, Misztal K, Bochtler M.

Cell Mol Life Sci. 2023

Publikacja

Divide-and-conquer approach to study protein tunnels in long molecular dynamics simulations.

Sequeiros-Borja CSurpeta B, Marchlewski IBrezovsky J.

MethodsX. 2023

Publikacja

NACDDB: Nucleic Acid Circular Dichroism Database.

Cappannini A, Mosca K, Mukherjee S, Moafinejad SN, Sinden RR, Arluison V, Bujnicki J, Wien F.

Nucleic Acids Res.. 2023

Publikacja

1D2DSimScore: A novel method for comparing contacts in biomacromolecules and their complexes.

Moafinejad SNPandaranadar Jeyeram IPN, Jaryani F, Shirvanizadeh N, Baulin EF, Bujnicki JM.

Protein Sci.. 2023

Measuring the tail: Methods for poly(A) tail profiling.

Brouze A, Krawczyk PS, Dziembowski A, Mroczek S.

Wiley Interdiscip Rev RNA.. 2023

2022

Publikacja

Zebrafish/Drosophila Dual System Model for Investigating Human Microcephaly.

Bartoszewski S, Dawidziuk M, Kasica N, Durak R, Jurek M, Podwysocka A, Guilbride DL, Podlasz P, Winata CL, Gawlinski PA.

Cells. 2022

Publikacja

Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish.

Uszczynska-Ratajczak B, Sugunan S, Kwiatkowska M, Migdal M, Carbonell-Sala S, Sokol A, Winata CL, Chacinska A.

Life Sci Alliance. 2022

Publikacja

Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.

Baranasic D, Hörtenhuber M, Balwierz PJ, Zehnder T, Mukarram AK, Nepal C, Várnai C, Hadzhiev Y, Jimenez-Gonzalez A, Li N, Wragg J, D'Orazio FM, Relic D, Pachkov M, Díaz N, Hernández-Rodríguez B, Chen Z, Stoiber M, Dong M, Stevens I, Ross SE, Eagle A, Martin R, Obasaju O, Rastegar S, McGarvey AC, Kopp W, Chambers E, Wang D, Kim HR, Acemel RD, Naranjo S, Łapiński M, Chong V, Mathavan S, Peers B, Sauka-Spengler T, Vingron M, Carninci P, Ohler U, Lacadie SA, Burgess SM, Winata C, van Eeden F, Vaquerizas JM, Gómez-Skarmeta JL, Onichtchouk D, Brown BJ, Bogdanovic O, van Nimwegen E, Westerfield M, Wardle FC, Daub CO, Lenhard B, Müller F.

Nat Genet.. 2022

Publikacja

Obesity in Caucasian Seniors on the Rise: Is It Truly Harmful? Results of the PolSenior2 Study.

Puzianowska-Kuznicka M, Kurylowicz A, Wierucki L, Owczarek AJ, Jagiello K, Mossakowska M, Zdrojewski T, Chudek J.

Nutrients.. 2022

Publikacja

TRIM25 mutation (p.C168*), coding for an E3 ubiquitin ligase, is a cause of early-onset autosomal dominant dementia with amyloid load and parkinsonism.

Gómez-Tortosa E, Baradaran-Heravi Y, Dillen L, Choudhury NR, Agüero Rabes P, Pérez-Pérez J, Kocoglu C, Sainz MJ, Ruiz González A, Téllez R, Cremades-Jimeno L, Cárdaba B; EU EOD Consortium, Van Broeckhoven C, Michlewski G, van der Zee J.

Alzheimers Dement.. 2022

Publikacja

Development of the brain ventricular system from a comparative perspective.

Korzh V.

Clin Anat.. 2022

Preprint

Pheromone-dependent olfaction bidirectionally regulates muscle extracellular vesicles formation.

Banasiak K, Szczepańska A, Kołodziejska K, Ibrahim AT, Pokrzywa W, Turek M.

bioRxiv. 2022

Publikacja

Electrostatic Interaction with the Bacterial Cell Envelope Tunes the Lytic Activity of Two Novel Peptidoglycan Hydrolases.

Wysocka A, Łężniak Ł, Jagielska E, Sabała I.

Microbiol Spectr. . 2022

Preprint

Dynactin interaction with AP-2 adaptor complex requires CLIP-170 and autophagy.

Tempes A, Bogusz K, Brzozowska A, Weslawski J, Macias M, Lew A, Calka-Kresa M, Bernas T, Szczepankiewicz AA, Bakun M, Rubel T, Malik AR, Jaworski J.

bioRxiv. 2022

Publikacja

Mitofusin 2 Integrates Mitochondrial Network Remodelling, Mitophagy and Renewal of Respiratory Chain Proteins in Neurons after Oxygen and Glucose Deprivation.

Wojtyniak P, Boratynska-Jasinska A, Serwach K, Gruszczynska-Biegala J, Zablocka B, Jaworski J, Kawalec M.

Mol Neurobiol. . 2022

Publikacja

Modeling the Structure, Dynamics, and Transformations of Proteins with the UNRES Force Field.

Sieradzan AK, Czaplewski C, Krupa P, Mozolewska MA, Karczyńska AS, Lipska AG, Lubecka EA, Gołaś E, Wirecki T, Makowski M, Ołdziej S, Liwo A.

Methods Mol Biol. . 2022

Publikacja

Computational Pipeline for Reference-Free Comparative Analysis of RNA 3D Structures Applied to SARS-CoV-2 UTR Models.

Gumna J, Antczak M, Adamiak RW, Bujnicki JM, Chen SJ, Ding F, Ghosh P, Li J, Mukherjee S, Nithin C, Pachulska-Wieczorek K, Ponce-Salvatierra A, Popenda M, Sarzynska J, Wirecki T, Zhang D, Zhang S, Zok T, Westhof E, Miao Z, Szachniuk M, Rybarczyk A.

Int J Mol Sci. . 2022

Publikacja

MicroRNA Expression Profile in TSC Cell Lines and the Impact of mTOR Inhibitor.

Pawlik B, Grabia S, Smyczyńska U, Fendler W, Dróżdż I, Liszewska E, Jaworski J, Kotulska K, Jóźwiak S, Młynarski W, Trelińska J.

Int J Mol Sci.. 2022

Publikacja

TENT5 cytoplasmic noncanonical poly(A) polymerases regulate the innate immune response in animals.

Liudkovska V, Krawczyk PS, Brouze A, Gumińska N, Wegierski T, Cysewski D, Mackiewicz Z, Ewbank JJ, Drabikowski K, Mroczek S, Dziembowski A.

Sci Adv.. 2022

Publikacja

Disrupting interaction between miR-132 and Mmp9 3'UTR improves synaptic plasticity and memory in mice.

Kuzniewska B, Rejmak K, Nowacka A, Ziółkowska M, Milek J, Magnowska M, Gruchota J, Gewartowska O, Borsuk E, Salamian A, Dziembowski A, Radwanska K, Dziembowska M.

Front Mol Neurosci.. 2022

Preprint

In silico analysis of the profilaggrin sequence indicates alterations in the stability, degradation route, and intracellular protein fate in filaggrin null mutation carriers. 

Argho A.P, Szulc N, Kobiela A, Brown SJ, Pokrzywa W, Gutowska-Owsiak D.

Research Square. 2022

Publikacja

Competition between electrostatic interactions and halogen bonding in the protein–ligand system: structural and thermodynamic studies of 5,6-dibromobenzotriazole-hCK2α complexes.

Winiewska‑Szajewska M, Czapinska H, Kaus‑Drobek M, Fricke A, Mieczkowska K, Dadlez M, Bochtler M, Poznański J.

Sci Rep.. 2022

Publikacja

A novel de novo FEM1C variant is linked to neurodevelopmental disorder with absent speech, pyramidal signs, and limb ataxia.

Dubey AA, Krygier M, Szulc NA, Rutkowska K, Kosińska J, Pollak A, Rydzanicz M, Kmieć T, Mazurkiewicz-Bełdzińska M, Pokrzywa W, Płoski R.

Human Molecular Genetics. 2022

Publikacja

The Prevalence of Anticitrullinated Protein Antibodies in Older Poles—Results from a Population-Based PolSenior Study

Chudek A, Kotyla P, Mossakowska M, Grodzicki T,
Zdrojewski T, Olszanecka-Glinianowicz M, Chudek J, Owczarek AJ.

Int. J. Environ. Res. Public Health. 2022

Publikacja

Evidence for a fragile X messenger ribonucleoprotein 1 (FMR1) mRNA gain-of-function toxicity mechanism contributing to the pathogenesis of fragile X-associated premature ovarian insufficiency.

Rosario R, Stewart HL, Choudhury NR, Michlewski G, Charlet-Berguerand N, Anderson RA.

FASEB J. 2022. 2022

Publikacja

Out-of-pocket expenses of patients with inflammatory bowel disease: a comparison of patient-reported outcomes across 12 European countries.

Holko P, Kawalec P, Sajak-Szczerba M, Avedano L, Mossakowska M.

Eur J Health Econ.. 2022

Publikacja

Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes.

Sekar R, Motzler K, Kwon Y, Novikoff A, Jülg J, Najafi B, Wang S, Warnke AL, Seitz S, Hass D, Gancheva S, Kahl S, Yang B, Finan B, Schwarz K, Okun JG, Roden M, Blüher M, Müller TD, Krahmer N, Behrends C, Plettenburg O, Miaczynska M, Herzig S, Zeigerer A.

Cell Metab.. 2022

Publikacja

Generation of three human iPSC lines from patients with Huntington’s disease with different CAG lengths and human control iPSC line from a healthy donor.

Latoszek E, Piechota M, Liszewska E, Hansíkova ́H, Klempír J,
Mühlback A, Landwehrmeyer GB, Kuznicki J, Czeredys M.

Stem Cell Res.. 2022

Publikacja

Prevalence and risk factors of untreated thyroid dysfunctions in the older Caucasian adults: Results of PolSenior 2 survey.

Kocełak P, Mossakowska M, Puzianowska-Kuźnicka M, Sworczak K, Wyszomirski A, Handzlik G, Stefański A, Zdrojewski T, Chudek J.

PLoS One. 2022

Publikacja

Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function.

Ravichandran M, Rafalski D, Davies CI, Ortega-Recalde O, Nan X, Glanfield CR, Kotter A, Misztal K, Wang AH, Wojciechowski M, Rażew M, Mayyas IM, Kardailsky O, Schwartz U, Zembrzycki K, Morison IM, Helm M, Weichenhan D, Jurkowska RZ, Krueger F, Plass C, Zacharias M, Bochtler M, Hore TA, Jurkowski TP.

Sci Adv.. 2022

Publikacja

The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells.

Oroń M, Grochowski M, Jaiswar A, Legierska J, Jastrzębski K, Nowak-Niezgoda M, Kołos M, Kaźmierczak W, Olesiński T, Lenarcik M, Cybulska M, Mikula M, Żylicz A, Miączyńska M, Zettl K, Wiśniewski JR, Walerych D.

Cell Rep.. 2022

Publikacja

Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish.

Niescierowicz K#, Pryszcz L#, Navarrete C#, Tralle E#, Sulej A#, Abu Nahia K, Kasprzyk ME, Misztal K, Pateria A, Pakuła A, Bochtler M, Winata C.

# Contributed equally

Nat Commun.. 2022

Publikacja

Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding.

Hyjek-Składanowska M, Anderson BA, Mykhaylyk V, Orr C, Wagner A, Poznański JT, Skowronek K, Seth P, Nowotny M.

Nucleic Acids Res.. 2022

Publikacja

miRNAs and isomiRs: Serum-Based Biomarkers for the Development of Intellectual Disability and Autism Spectrum Disorder in Tuberous Sclerosis Complex.

Scheper M, Romagnolo A, Besharat ZM, Iyer AM, Moavero R, Hertzberg C, Weschke B, Riney K, Feucht M, Scholl T, Petrak B, Maulisova A, Nabbout R, Jansen AC, Jansen FE, Lagae L, Urbanska M, Ferretti E, Tempes A, Blazejczyk M, Jaworski J, Kwiatkowski DJ, Jozwiak S, Kotulska K, Sadowski K, Borkowska J, Curatolo P, Mills JD, Aronica E, Epistop Consortium Members.

Biomedicines. 2022

Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.

Figiel M, Gapińska M, Czarnocki-Cieciura M, Zajko W, Sroka M, Skowronek K, Nowotny M.

Nucleic Acids Res.. 2022

SRF depletion in early life contributes to social interaction deficits in the adulthood.

Roszkowska M, Krysiak A, Majchrowicz L, Nader K, Beroun A, Michaluk P, Pekala M, Jaworski J, Kondrakiewicz L, Puścian A, Knapska E, Kaczmarek L, Kalita K.

Cell Mol Life Sci.. 2022

Mortality of older persons with and without abnormalities in the physical examination of arterial system.

Królczyk J, Piotrowicz K, Skalska A, Mossakowska M, Grodzicki T, Gąsowski J.

Aging Clin Exp Res. . 2022

A Dimer-Monomer Switch Controls CHIP-Dependent Substrate Ubiquitylation and Processing.

Balaji V, Müller L, Lorenz R, Kevei É, Zhang WH, Santiago U, Gebauer J, Llamas E, Vilchez D, Camacho CJ, Pokrzywa W, Hoppe T.

Mol Cell.. 2022

The Nε-rule for serine, but not cysteine catalytic triads.

Czapińska H, Bochtler M.

Angew Chem Int Ed Engl.. 2022

Loss of Unconventional Myosin VI Affects cAMP/PKA Signaling in Hindlimb Skeletal Muscle in an Age-Dependent Manner.

Lehka L, Wojton D, Topolewska M, Chumak V, Majewski Ł, Rędowicz MJ.

Front Physiol. 2022

Ferritin-mediated iron detoxification promotes hypothermia survival in Caenorhabditis elegans and murine neurons.

Pekec T, Lewandowski J, Komur AA, Sobańska D, Guo Y, Świtońska-Kurkowska K, Małecki JM, Dubey AA, Pokrzywa W, Frankowski M, Figiel M, Ciosk R.

Nat Commun.. 2022

Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.

Baranasic D et al. (Łapiński M.)

Nat Genet.. 2022

Indirect Costs of Inflammatory Bowel Diseases: A Comparison of Patient-Reported Outcomes Across 12 European Countries.

Holko P, Kawalec P, Sajak-Szczerba M, Avedano L, Mossakowska M.

Inflamm Bowel Dis.. 2022

Tollip-deficient zebrafish display no abnormalities in development, organ morphology or gene expression in response to lipopolysaccharide.

Wolińska-Nizioł L, Romaniuk K, Wojciechowska K, Surga K, Kamaszewski M, Szudrowicz H, Miączyńska M.

FEBS Open Bio.. 2022

A long noncoding RNA promotes parasite differentiation in African trypanosomes.

Guegan F, Rajan KS, Bento F, Pinto-Neves D, Sequeira M, Gumińska N, Mroczek S, Dziembowski A, Cohen-Chalamish S, Doniger T, Galili B, Estévez AM, Notredame C, Michaeli S, Figueiredo LM.

Sci Adv.. 2022

Higher ATM expression in lymphoblastoid cell lines from centenarian compared with younger women.

Hadar A, Voinsky I, Parkhomenko O, Puzianowska-Kuźnicka M, Kuźnicki J, Gozes I, Gurwitz D.

Drug Dev Res. . 2022

TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway.

*Choudhury NR, *Trus I, *Heikel G, Wolczyk M, Szymanski J, Bolembach A, Dos Santos Pinto RM, Smith N, Trubitsyna M, Gaunt E, Digard P, Michlewski G.

*joint first authors

Nucleic Acids Res.. 2022

Structural basis of transposon end recognition explains central features of Tn7 transposition systems.

Kaczmarska Z, Czarnocki-Cieciura M, Górecka-Minakowska KM, Wingo RJ, Jackiewicz J, Zajko W, Poznański JT, Rawski M, Grant T, Peters JE, Nowotny M.

Mol Cell.. 2022

fingeRNAt-A novel tool for high-throughput analysis of nucleic acid-ligand interactions.

Szulc NA, Mackiewicz Z, Bujnicki JM, Stefaniak F.

PLoS Comput Biol.. 2022

Molecular insights into RNA recognition and gene regulation by the TRIM-NHL protein Mei-P26.

Salerno-Kochan A, Horn A, Ghosh P, Nithin C, Kościelniak A, Meindl A, Strauss D, Krutyhołowa R, Rossbach O, Bujnicki JM, Gaik M, Medenbach J, Glatt S.

Life Sci Alliance. 2022

Endocytic trafficking of GAS6-AXL complexes is associated with sustained AKT activation.

Poświata A, Kozik K, Miączyńska M, Zdżalik-Bielecka D.

Cell Mol Life Sci.. 2022

DEGRONOPEDIA - a web server for proteome-wide inspection of degrons.

Szulc NA, Stefaniak F, Piechota M, Cappannini A, Bujnicki JM, Pokrzywa W.

bioRxiv preprint. 2022

CHIP ubiquitin ligase is involved in the nucleolar stress management.

Piechota M, Biriczova L, Kowalski K, Szulc NA, Pokrzywa W.

bioRxiv preprint. 2022

Common Dynamic Determinants Govern Quorum Quenching Activity in N-Terminal Serine Hydrolases.

Surpeta B, Grulich M, Palyzová A, Marešová H, Brezovsky J.

ACS Catal.. 2022

SRF depletion in early life contributes to social interaction deficits in the adulthood.

Roszkowska M, Krysiak A, Majchrowicz L, Nader K, Beroun A, Michaluk P, Pekala M, Jaworski J, Kondrakiewicz L, Puścian A, Knapska E, Kaczmarek L, Kalita K.

Cell Mol Life Sci.. 2022

Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities.

Corona A, Wycisk K, Talarico C, Manelfi C, Milia J, Cannalire R, Esposito F, Gribbon P, Zaliani A, Iaconis D, Beccari AR, Summa V, Nowotny M, Tramontano E.

ACS Pharmacol Transl Sci.. 2022

DNAzymeBuilder, a web application for in situ generation of RNA/DNA-cleaving deoxyribozymes.

Mohammadi-Arani R, Javadi-Zarnaghi F, Boccaletto P, Bujnicki JM, Ponce-Salvatierra A.

Nucleic Acids Res.. 2022

The Pet127 protein is a mitochondrial 5'-to-3' exoribonuclease from the PD-(D/E)XK superfamily involved in RNA maturation and intron degradation in yeasts.

Labedzka-Dmoch K, Razew M, Gapinska M, Piatkowski J, Kolondra A, Salmonowicz H, Wenda JM, Nowotny M, Golik P.

RNA. 2022

ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway.

Wróbel M, Cendrowski J, Szymańska E, Grębowicz-Maciukiewicz M, Budick-Harmelin N, Macias M, Szybińska A, Mazur M, Kolmus K, Goryca K, Dąbrowska M, Paziewska A, Mikula M, Miączyńska M.

Life Sci Alliance. 2022

Benchtop X-band electron paramagnetic resonance detection of melanin and Nitroxyl spin probe in zebrafish.

Makarova K, Zawada K, Wiweger M.

Free Radical Biology and Medicine. 2022

Siah‑1‑interacting protein regulates mutated huntingtin protein aggregation in Huntington’s disease models.

Latoszek E, Wiweger M, Ludwiczak J, Dunin‑Horkawicz S, Kuznicki J, Czeredys M.

Cell & Bioscience. 2022

Polypharmacy in Polish Older Adult Population-A Cross-Sectional Study: Results of the PolSenior Project.

Neumann-Podczaska A, Tobis S, Antimisiaris D, Mossakowska M, Puzianowska-Kuznicka M, Chudek J, Wierucki L, Merks P, Wizner B, Sobieszczanska M, Niemir ZI, Kaczmarek B, Wieczorowska-Tobis K.

Int J Environ Res Public Health.. 2022

TransportTools: a library for high-throughput analyses of internal voids in biomolecules and ligand transport through them.

Brezovsky J, Thirunavukarasu AS, Surpeta B, Sequeiros-Borja CE, Mandal N, Sarkar DK, Dongmo Foumthuim CJ, Agrawal N.

Bioinformatics. 2022

MODOMICS: a database of RNA modification pathways. 2021 update.

Boccaletto P, Stefaniak F, Ray A, Cappannini A, Mukherjee S, Purta E, Kurkowska M, Shirvanizadeh N, Destefanis E, Groza P, Avşar G, Romitelli A, Pir P, Dassi E, Conticello SG, Aguilo F, Bujnicki JM.

Nucleic Acids Res.. 2022

Bemcentinib and gilteritinib inhibit cell growth and impair the endo-lysosomal and autophagy systems in an AXL-independent manner.

Zdzalik-Bielecka D, Kozik K, Poswiata A, Jastrzebski K, Jakubik M, Miaczynska M.

Mol Cancer Res. . 2022

Disparate effects of ankle‑brachial index on mortality in the ‘very old’ and ‘younger old’ populations‑the PolSenior survey.

Królczyk  J, Skalska A, Piotrowicz K, Mossakowska M, Grodzicki T, Gąsowski J.

Heart Vessels. 2022

Publikacja

A heterotypic assembly mechanism regulates CHIP E3 ligase activity.

Das A, Thapa P, Santiago U, Shanmugam N, Banasiak K, Dabrowska K, Nolte H, Szulc NA, Gathungu RM, Cysewski D, Krüger M, Dadlez M, Nowotny M, Camacho CJ, Hoppe T, Pokrzywa W.

EMBO J. . 2022

2021

Socioeconomic Risk Factors of Poor Nutritional Status in Polish Elderly Population: The Results of PolSenior2 Study.

Krzymińska-Siemaszko R, Deskur-Śmielecka E, Kaluźniak-Szymanowska A, Kaczmarek B, Kujawska-Danecka H, Klich-Rączka A, Mossakowska M, Małgorzewicz S, Dworak LB, Kostka T, Chudek J, Wieczorowska-Tobis K.

Nutrients.. 2021

Constrained peptides mimic a viral suppressor of RNA silencing.

Kuepper A, McLoughlin NM, Neubacher S, Yeste-Vázquez A, Collado Camps E, Nithin C, Mukherjee S, Bethge L, Bujnicki JM, Brock R, Heinrichs S, Grossmann TN.

Nucleic Acids Res. . 2021

Annexin A3: a newly identified player in store‑operated calcium entry.

Dyrda A, Kuznicki J, Majewski L.

Acta Neurobiol Exp . 2021

Multi-omics analyses of early liver injury reveals cell-type-specific transcriptional and epigenomic shift.

Migdał M, Tralle E, Abu Nahia K, Bugajski Ł, Kędzierska KZ, Garbicz F, Piwocka K, Winata CL, Pawlak M.

BMC Genomics.. 2021

Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae.

Turtola M, Manav MC, Kumar A, Tudek A, Mroczek S, Krawczyk PS, Dziembowski A, Schmid M, Passmore LA, Casañal A, Jensen TH.

Genes Dev.. 2021

Chemotherapy of HER2- and MDM2-Enriched Breast Cancer Subtypes Induces Homologous Recombination DNA Repair and Chemoresistance.

Herok M, Wawrzynow B, Maluszek MJ, Olszewski MB, Zylicz A, Zylicz M.

Cancers (Basel). 2021

Modular self-assembly system for development of oligomeric, highly internalizing and potent cytotoxic conjugates targeting fibroblast growth factor receptors.

Poźniak M, Porębska N, Jastrzębski K, Krzyścik MA, Kucińska M, Zarzycka W, Barbach A, Zakrzewska M, Otlewski J, Miączyńska M, Opaliński Ł.

J Biomed Sci.. 2021

The Multiple Facets of Iron Recycling.

Slusarczyk P, Mleczko-Sanecka K.

Genes (Basel). 2021

The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis.

Scheer H, de Almeida C, Ferrier E, Simonnot Q, Poirier L, Pflieger D, Sement FM, Koechler S, Piermaria C, Krawczyk P, Mroczek S, Chicher J, Kuhn L, Dziembowski A, Hammann P, Zuber H, Gagliardi D.

Nat Commun.. 2021

Patterns of multimorbidity in 4588 older adults. Implications for non-geriatrician specialist.

Piotrowicz K, Pac A, Skalska A, Mossakowska M, Chudek J, Zdrojewski T, Więcek A, Grodzicki T, Gąsowski J.

Pol Arch Intern Med. 2021

Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae.

Tudek A, Krawczyk PS, Mroczek S, Tomecki R, Turtola M, Matylla-Kulińska K, Jensen TH, Dziembowski A.

Nat Commun. . 2021

Prevention of Epilepsy in Infants with Tuberous Sclerosis Complex in the EPISTOP Trial.

Kotulska K, Kwiatkowski DJ, Curatolo P, Weschke B, Riney K, Jansen F, Feucht M, Krsek P, Nabbout R, Jansen AC, Wojdan K, Sijko K, Głowacka-Walas J, Borkowska J, Sadowski K, Domańska-Pakieła D, Moavero R, Hertzberg C, Hulshof H, Scholl T, Benova B, Aronica E, de Ridder J, Lagae L, Jóźwiak S; EPISTOP Investigators (Jaworski J, Błażejczyk M, Tempes A, Urbańska M.)

Ann Neurol. 2021

Serum Uric Acid Is a Weak Independent Predictor of Overall Survival in Older Adults.

Winder M, Owczarek AJ, Mossakowska M, Holecki M, Broczek K, Grodzicki T, Zdrojewski T, Chudek J.

J Clin Med.. 2021

Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker.

Minhas R, Loeffler-Wirth H, Siddiqui YH, Obrębski T, Vashisht S, Abu Nahia K, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL.

BMC Genomics.. 2021

Two New M23 Peptidoglycan Hydrolases With Distinct Net Charge.

Wysocka A, Jagielska E, Łężniak Ł, Sabała I.

Front Microbiol.. 2021

Genomic and physiological analyses of the zebrafish atrioventricular canal reveal molecular building blocks of the secondary pacemaker region.

Abu Nahia K, Migdał M, Quinn TA, Poon KL, Łapiński M, Sulej A, Liu J, Mondal SS, Pawlak M, Bugajski Ł, Piwocka K, Brand T, Kohl P, Korzh V, Winata C.

Cell Mol Life Sci.. 2021

RNA pull-down confocal nanoscanning (RP-CONA) detects quercetin as pri-miR-7/HuR interaction inhibitor that decreases α-synuclein levels.

Zhu S, Choudhury NR, Rooney S, Pham NT, Koszela J, Kelly D, Spanos C, Rappsilber J, Auer M, Michlewski G.

Nucleic Acids Res.. 2021

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants.

NCD Risk Factor Collaboration (NCD-RisC) (Mossakowska M.)

Lancet. 2021

Maintaining proteostasis under mechanical stress.

Höhfeld J, Benzing T, Bloch W, Fürst DO, Gehlert S, Hesse M, Hoffmann B, Hoppe T, Huesgen PF, Köhn M, Kolanus W, Merkel R, Niessen CM, Pokrzywa W, Rinschen MM, Wachten D, Warscheid B.

EMBO Rep.. 2021

Causes of Anemia in Polish Older Population-Results from the PolSenior Study.

Styszyński A, Chudek J, Mossakowska M, Lewandowski K, Puzianowska-Kuźnicka M, Klich-Rączka A, Więcek A, Wieczorowska-Tobis K.

Cells. 2021

High behavioural variability mediated by altered neuronal excitability in auts2 mutant zebrafish.

Jha U, Kondrychyn I, Korzh V, Thirumalai V.

bioRxiv. 2021

Cardiac-specific β-catenin deletion dysregulates energetic metabolism and mitochondrial function in perinatal cardiomyocytes.

Balatskyi VV, Vaskivskyi VO, Myronova A, Avramets D, Nahia KA, Macewicz LL, Ruban TP, Kucherenko DY, Soldatkin OO, Lushnikova IV, Skibo GG, Winata CL, Dobrzyn P, Piven OO.

Mitochondrion.. 2021

Defining a novel domain that provides an essential contribution to site-specific interaction of Rep protein with DNA.

Wegrzyn K, Zabrocka E, Bury K, Tomiczek B, Wieczor M, Czub J, Uciechowska U, Moreno-Del Alamo M, Walkow U, Grochowina I, Dutkiewicz R, Bujnicki JM, Giraldo R, Konieczny I.

Nucleic Acids Res.. 2021

Muscle-derived exophers promote reproductive fitness.

Turek M, Banasiak K, Piechota M, Shanmugam N, Macias M, Śliwińska MA, Niklewicz M, Kowalski K, Nowak N, Chacinska A, Pokrzywa W.

EMBO Rep.. 2021

The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion.

Zdżalik-Bielecka D, Poświata A, Kozik K, Jastrzębski K, Schink KO, Brewińska-Olchowik M, Piwocka K, Stenmark H, Miączyńska M.

Proc Natl Acad Sci USA. 2021

Distinction between self and non-self in restriction modification: The mysterious case of type IIL enzymes.

Bochtler M.

Structure. 2021

Structures of substrate complexes of foamy viral protease-reverse transcriptase.

Nowacka M, Nowak E, Czarnocki-Cieciura M, Jackiewicz J, Skowronek K, Szczepanowski R, Wöhrl BM, Nowotny M.

J Virol.. 2021

Structural Characterization of EnpAD,L-Endopeptidase from Enterococcus faecalis Prophage Provides Insights into Substrate Specificity of M23Peptidases.

Małecki PH, Mitkowski P, Jagielska E, Trochimiak K, Mesnage S, Sabała I.

. 2021

Staphylococcus aureus Specific Electrospun Wound Dressings: Influence of Immobilization Technique on Antibacterial Efficiency of Novel Enzybiotic.

Urbanek O, Wysocka A, Nakielski P, Pierini F, Jagielska E, Sabała I.

Pharmaceutics. . 2021

The development of zebrafish pancreas affected by deficiency of Hedgehog signaling.

Korzh S, Winata CL, Gong Z, Korzh V.

Gene Expr Patterns.. 2021

G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.

Prentzell MT et al. (Jaworski J, Kedra M, Kopach A, Macias M, Zmorzynska J.)

Cell. 2021

Cytoplasmic polyadenylation by TENT5A is required for proper bone formation.

Gewartowska O, Aranaz-Novaliches G, Krawczyk PS, Mroczek S, Kusio-Kobiałka M, Tarkowski B, Spoutil F, Benada O, Kofroňová O, Szwedziak P, Cysewski D, Gruchota J, Szpila M, Chlebowski A, Sedlacek R, Prochazka J, Dziembowski A.

Cell Rep.. 2021

Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2.

Czapinska H, Winiewska-Szajewska M, Szymaniec-Rutkowska A, Piasecka A, Bochtler M, Poznański J.

J Phys Chem B.. 2021

AnnapuRNA: A scoring function for predicting RNA-small molecule binding poses.

Stefaniak F, Bujnicki JM.

PLoS Comput Biol.. 2021

RNA and DNA G-quadruplexes bind to human dicer and inhibit its activity.

Koralewska N, Szczepanska A, Ciechanowska K, Wojnicka M, Pokornowska M, Milewski MC, Gudanis D, Baranowski D, Nithin C, Bujnicki JM, Gdaniec Z, Figlerowicz M, Kurzynska-Kokorniak A.

Cell Mol Life Sci.. 2021

mTOR controls endoplasmic reticulum-Golgi apparatus trafficking of VSVg in specific cell types.

Koscielny A, Liszewska E, Machnicka K, Wezyk M, Kotulska K, Jaworski J.

Cell Mol Biol Lett.. 2021

Fish-Ing for Enhancers in the Heart.

Parisi C, Vashisht S, Winata CL.

J Mol Sci.. 2021

Functions and mechanisms of RNA tailing by metazoan terminal nucleotidyltransferases.

Liudkovska V, Dziembowski A.

Wiley Interdiscip Rev RNA.. 2021

Caffeine-Cyclodextrin Complexes as Solids: Synthesis, Biological and Physicochemical Characterization.

Szmeja S, Gubica T, Ostrowski A, Zalewska A, Szeleszczuk Ł, Zawada K, Zielińska-Pisklak M, Skowronek K, Wiweger M.

Int J Mol Sci.. 2021

npc2-Deficient Zebrafish Reproduce Neurological and Inflammatory Symptoms of Niemann-Pick Type C Disease.

Wiweger M, Majewski L, Adamek-Urbanska D, Wasilewska I, Kuznicki J.

Front Cell Neurosci.. 2021

Evolutionary context can clarify gene names: Teleosts as a case study.

Gasanov EV, Jędrychowska J, Kuźnicki J, Korzh V.

BioEssays. 2021

Molecular Components of Store-Operated Calcium Channels in the Regulation of Neural Stem Cell Physiology, Neurogenesis, and the Pathology of Huntington’s Disease.

Latoszek E, Czeredys M.

Front Cell Dev Biol.. 2021

Dissecting biological activities of fibroblast growth factor receptors by the coiled-coil-mediated oligomerization of FGF1.

Porebska N, Pozniaka M, Krzyscik MA, Knapika A, Czyrek A, Kucinska M, Jastrzebski K, Zakrzewska M, Otlewski J, Opalinski L.

Int J Biol Macromol.. 2021

Prevalence and socioeconomic predictors of diagnosed and undiagnosed diabetes in oldest-old and younger Caucasian seniors: results from the PolSenior study.

Puzianowska-Kuźnicka M, Januszkiewicz-Caulier J, Kuryłowicz A, Mossakowska M, Zdrojewski T, Szybalska A, Skalska A, Chudek J, Franek E.

Endokrynol Pol.. 2021

The Dose-Dependent Pleiotropic Effects of the UBB+1 Ubiquitin Mutant.

Banasiak K, Szulc NA, Pokrzywa W.

Front. Mol. Biosci. . 2021

Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight.

NCD Risk Factor Collaboration (Mossakowska M.)

eLife. . 2021

DNAmoreDB, a database of DNAzymes.

Ponce-Salvatierra A, Boccaletto P, Bujnicki JM.

Nucleic Acids Res.. 2021

Exploring Translational Control of Maternal mRNAs in Zebrafish.

Winata  CL, Łapiński  M, Ismail  H, Mathavan  S, Sampath P.

Methods Mol Biol.. 2021

Establishment of two hiPSC lines (IIMCBi001-A and IIMCBi002-A) from dermal fibroblasts of healthy donors and characterization of their cell cycle.

Liszewska E, Majchrowicz L, Krogulec E, Kotulska K, Kaczmarek L, Kalita K, Dobrzyń A, Jaworski J.

Stem Cell Res.. 2021

Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA.

Pastor M, Czapinska H, Helbrecht I, Krakowska K, Lutz T, Xu S, Bochtler M.

Nucleic Acids Res.. 2021

Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses.

Kolmus K, Erdenebat P, Szymańska E, Stewig B, Goryca K, Derezinska-Wolek E, Szumera-Cieckiewicz A, Brewinska-Olchowik M, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miaczynska M.

J Cell Sci.. 2021

Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect.

Warminski  M, Kowalska  J, Nowak E, Kubacka  D, Tibble  R, Kasprzyk  R, Sikorski  PJ, Gross  JD, Nowotny  M, Jemielity J.

ACS Chem Biol.. 2021

Prevalence of Hyperuricemia and the Use of Allopurinol in Older Poles-Results from a Population-Based PolSenior Study.

Winder M, Owczarek AJ, Mossakowska M, Broczek K, Grodzicki T, Wierucki Ł, Chudek J.

Int J Environ Res Public Health.. 2021

Kcnb1 plays a role in development of the inner ear.

Jedrychowska J, Gasanov EV, Korzh V.

Dev Biol.. 2021

An improved method for precise genome editing in zebrafish using CRISPR-Cas9 technique.

Gasanov EV, Jędrychowska J, Pastor M, Wiweger M, Methner A, Korzh VP.

Mol Biol Rep.. 2021

DNA adenine methylation in eukaryotes: Enzymatic mark or a form of DNA damage?

Bochtler M, Fernandes H.

BioEssays. 2021

Cell-type-specific insights into iron regulatory processes.

Mleczko-Sanecka K, Silvestri L.

Am J Hematol.. 2021

Camel regulates development of the brain ventricular system.

Yang S, Emelyanov A, You MS, Sin M, Korzh V.

Cell Tissue Res.. 2021

Recent advances in user-friendly computational tools to engineer protein function.

Sequeiros-Borja CE, Surpeta B, Brezovsky J.

Briefings in Bioinformatics. 2021

2020

Health status and its socio-economic covariates in the older population in Poland - the assumptions and methods of the nationwide, cross-sectional PolSenior2 survey.

Wierucki Ł, Kujawska-Danecka H, Mossakowska M, Grodzicki T, Błędowski P, Chudek J, Kostka T, Więcek A, Hajduk A, Bandosz P, Zagożdżon P, Wojtyniak B, Zdrojewski T.

Arch Med Sci.. 2020

Luciferase reporter assay for small-molecule inhibitors of MIR92b-3p function: Screening cyanopeptolins produced by Nostoc from the Baltic Sea.

Brzuzan P, Mazur-Marzec H, Florczyk M, Stefaniak F, Fidor A, Konkel R, Woźny M.

Toxicol In Vitro.. 2020

Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase.

Andryianau G, Kowalski M, Piotrowicz MC, Rajkiewicz AA, Dymek B, Sklepkiewicz PL, Pluta E, Stefaniak F, Czestkowski W, Olejniczak S, Mazur M, Niedziejko P, Koralewski R, Matyszewski K, Gruza M, Zagozdzon A, Salamon M, Rymaszewska A, Welzer M, Dzwonek K, Golab J, Olczak J, Bartoszewicz A, Golebiowski A.

ACS Med Chem Lett.. 2020

Blood Lipids and Cognitive Performance of Aging Polish Adults: A Case-Control Study Based on the PolSenior Project.

McFarlane O, Kozakiewicz M, Kędziora-Kornatowska K, Gębka D, Szybalska A, Szwed M, Klich-Rączka A.

Front Aging Neurosci.. 2020

β-Catenin Regulates Cardiac Energy Metabolism in Sedentary and Trained Mice.

Balatskyi VV, Palchevska OL, Bortnichuk L, Gan AM, Myronova A, Macewicz LL, Navrulin VO, Tumanovska LV, Olichwier A, Dobrzyn P, Piven OO.

Life (Basel). 2020

The zebrafish as a model for developmental and biomedical research in Poland and beyond.

Winata CL, Dodzian J, Bialek-Wyrzykowska U.

Dev Biol.. 2020

The expression of Rpb10, a small subunit common to RNA polymerases, is modulated by the R3H domain-containing Rbs1 protein and the Upf1 helicase.

Cieśla M, Turowski TW, Nowotny M, Tollervey D, Boguta M.

Nucleic Acids Res.. 2020

Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.

Koralewski R, Dymek B, Mazur M, Sklepkiewicz P, Olejniczak S, Czestkowski W, Matyszewski K, Andryianau G, Niedziejko P, Kowalski M, Gruza M, Borek B, Jedrzejczak K, Bartoszewicz A, Pluta E, Rymaszewska A, Kania M, Rejczak T, Piasecka S, Mlacki M, Mazurkiewicz M, Piotrowicz M, Salamon M, Zagozdzon A, Napiorkowska-Gromadzka A, Bartlomiejczak A, Mozga W, Dobrzański P, Dzwonek K, Golab J, Nowotny M, Olczak J, Golebiowski A.

J Med Chem.. 2020

Disulfide bridge cross-linking between protein and the RNA backbone as a tool to study RNase H1.

Hyjek-Składanowska M, Stasińska AR, Napiórkowska-Gromadzka A, Bartłomiejczak A, Seth PP, Chmielewski MK, Nowotny M.

Bioorg Med Chem. . 2020

Evolutionary History and Activity of RNase H1-Like Proteins in Arabidopsis thaliana.

Kuciński J, Chamera S, Kmera A, Rowley MJ, Fujii S, Khurana P, Nowotny M, Wierzbicki AT.

Plant Cell Physiol.. 2020

Facultative Parthenogenesis in a Diamondback Water Snake (Nerodia rhombifer).

Gasanov EV, Katz AV.

Russ J Herpetol.. 2020

BDNF Val66Met Polymorphism, the Allele-Specific Analysis by qRT-PCR - a Novel Protocol.

de Assis GG, Hoffman JR, Gasanov EV.

Int J Med Sci.. 2020

Respiratory Syndrome Coronavirus Infections: Possible Mechanisms of Neurological Implications-A Systematic Review.

de Assis GG, Murawska-Cialowicz E, Cieszczyk P, Gasanov EV.

Front Neurol.. 2020

Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions.

Veerapathiran S, Teh C, Zhu S, Kartigayen I, Korzh V, Matsudaira PT, Wohland T.

eLife. 2020

Dysregulation of Neuronal Calcium Signaling via Store-Operated Channels in Huntington’s Disease.

Czeredys M.

Front Cell Dev Biol.. 2020

Clathrin- and dynamin-dependent endocytosis limits canonical NF-κB signaling triggered by lymphotoxin β receptor.

Maksymowicz M, Miączyńska M, Banach-Orłowska M.

Cell Commun Signal.. 2020

Pathogenic Variants in the Myosin Chaperone UNC-45B Cause Progressive Myopathy with Eccentric Cores.

Donkervoort S, Kutzner CE, Hu Y, Lornage X, Rendu J, Stojkovic T, Baets J, Neuhaus SB, Tanboon J, Maroofian R, Bolduc V, Mroczek M, Conijn S, Kuntz NL, Töpf A, Monges S, Lubieniecki F, McCarty RM, Chao KR, Governali S, Böhm J, Boonyapisit K, Malfatti E, Sangruchi T, Horkayne-Szakaly I, Hedberg-Oldfors C, Efthymiou S, Noguchi S, Djeddi S, Iida A, di Rosa G, Fiorillo C, Salpietro V, Darin N, Faure´ J, Houlden H, Oldfors A, Nishino I, de Ridder W, Straub V, Pokrzywa W, Laporte J, Foley R, Romero NB, Ottenheijm C, Hoppe T, Bönnemann CG.

Am. J. Hum. Genet.. 2020

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants.

NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M & Slusarczyk P.

Lancet. 2020

Age-related differences in vitamin D status in Polish centenarians compared with 65-year-olds.

Kupisz-Urbańska M, Broczek K, Galus K, Mossakowska M, Marcinowska-Suchowierska E.

Pol Arch Intern Med. 2020

Reversal of nucleobase methylation by dioxygenases.

Xu G-L, Bochtler M.

Nat Chem Biol. 2020

Splicing variants of an endocytic regulator, BMP2K, differentially control autophagic degradation in erythroid cells.

Cendrowski J, Miaczynska M.

Autophagy. 2020

Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine..

Malik D, Kobyłecki K, Krawczyk P, Poznański J, Jakielaszek A, Napiórkowska A, Dziembowski A, Tomecki R, Nowotny M.

Nucleic Acids Res.. 2020

HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells.

Sojka DR, Gogler-Pigłowska A, Klarzyńska K, Klimczak M, Zylicz A, Głowala-Kosińska M, Krawczyk Z, Scieglinska D.

Cancers (Basel). 2020

Productivity Loss Among Parents of Children With Inflammatory Bowel Diseases in Relation to Disease Activity and Patient's Quality of Life.

Stawowczyk E, Kawalec P, Kowalska-Duplaga K, Mossakowska M.

J Pediatr Gastroenterol Nutr.. 2020

CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage.

Albert M-C, Brinkmann K, Pokrzywa W, Günther SD, Krönke M, Hoppe T, Kashkar H.

Cell Death & Disease. 2020

Knockout of stim2a Increases Calcium Oscillations in Neurons and Induces Hyperactive-Like Phenotype in Zebrafish Larvae.

Gupta RK, Wasilewska I, Palchevska O, Kuźnicki J.

Int. J. Mol. Sci.. 2020

Targeted RNA Knockdown by a Type III CRISPR-Cas Complex in Zebrafish.

Fricke T, Smalakyte D, Lapinski M, Pateria A, Weige C, Pastor M, Kolano A, Winata C, Siksnys V, Tamulaitis G, Bochtler M.

CRISPR J.. 2020

Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells.

Cendrowski J, Kaczmarek M, Mazur M, Kuzmicz-Kowalska K, Jastrzebski K, Brewinska-Olchowik M, Kominek A, Piwocka K, Miaczynska M.

eLife . 2020

Protein Domain Guided Screen for Sequence Specific and Phosphorothioate-Dependent Restriction Endonucleases.

Lutz T, Czapinska H, Fomenkov A, Potapov V, Heiter DF, Cao B, Dedon P, Bochtler M, Xu S.

Front. Microbiol.. 2020

RNAProbe: a web server for normalization and analysis of RNA structure probing data.

Wirecki TK, Merdas K, Bernat A, Boniecki MJ, Bujnicki JM, Stefaniak F.

Nucleic Acids Res. . 2020

TSC2 pathogenic variants are predictive of severe clinical manifestations in TSC infants: results of the EPISTOP study.

Ogórek B, Hamieh L, Hulshof HM, Lasseter K, Klonowska K, Kuijf H, Moavero R, Hertzberg C, Weschke B, Riney K, Feucht M, Scholl T, Krsek P, Nabbout R, Jansen AC, Benova B, Aronica E, Lagae L, Curatolo P, Borkowska J, Sadowski K, Domańska-Pakieła D, Janson S, Kozlowski P, Urbanska M, Jaworski J, Jozwiak S, Jansen FE, Kotulska K; EPISTOP Consortium members, Kwiatkowski DJ.

Genet Med. . 2020

IQGAP1-dysfunction leads to induction of senescence in human vascular smooth muscle cells.

Grabowska W, Achtabowska N, Klejman A, Skowronek K, Calka M, Bielak-Zmijewska A.

Mech Ageing Dev.. 2020

Zebrafish Microenvironment Elevates EMT and CSC-Like Phenotype of Engrafted Prostate Cancer Cells.

Chen L, Olszewski MB, Kruithof-de MJ, Snaar-Jagalska BE.

Cells. 2020

Origin and development of circumventricular organs in living vertebrate.

Korzh V, Kondrychyn I.

Semin Cell Dev Biol.. 2020

Mitochondrial protein biogenesis in the synapse is supported by local translation.

Kuzniewska B, Cysewski D, Wasilewski M, Sakowska P, Milek J, Kulinski TM, Winiarski M, Kozielewicz P, Knapska E, Dadlez M, Chacinska A, Dziembowski A, Dziembowska M.

EMBO Rep.. 2020

Biological and Medical Importance of Cellular Heterogeneity Deciphered by Single-Cell RNA Sequencing.

Gupta RK, Kuznicki J.

Cells. 2020

Repositioning of the global epicentre of non-optimal cholesterol.

NCD Risk Factor Collaboration (Mossakowska M and Ślusarczyk P)

Nature. 2020

Nutritional status and fecundity are synchronised by muscular exopheresis.

Turek M, Piechota M, Shanmugam N, Niklewicz M, Kowalski K, Chacińska A, Pokrzywa W.

bioRxiv. 2020

stim2b Knockout Induces Hyperactivity and Susceptibility to Seizures in Zebrafish Larvae.

Wasilewska I, Gupta RK, Wojtaś B, Palchevska O, Kuźnicki J.

Cells. 2020

The effects of temperature on the proxies of visual detection of Danio rerio larvae: observations from the optic tectum.

Babkiewicz E, Bazała M, Urban P, Maszczyk P, Markowska M, Gliwicz M.

Biology Open . 2020

FGFR1 Clustering With Engineered Tetravalent Antibody Improves the Efficiency and Modifies the Mechanism of Receptor Internalization.

Pozniak M, Sokolowska-Wedzina A, Jastrzebski K, Szymczyk J, Porebska N, Krzyscik MA, Zakrzewska M, Miaczynska M, Otlewski J, Opalinski L.

Mol Oncol. . 2020

National Trends in Total Cholesterol Obscure Heterogeneous Changes in HDL and non-HDL Cholesterol and total-to-HDL Cholesterol Ratio: A Pooled Analysis of 458 Population-Based Studies in Asian and Western Countries.

NCD Risk Factor Collaboration (Mossakowska M and Ślusarczyk P)

Int J Epidemiol.. 2020

Targeting mitochondrial calcium pathways as a potential treatment against Parkinson’s disease.

Dey K, Bazala MA, Kuznicki J.

Cell Calcium. 2020

Restriction endonucleases that cleave RNA/DNAheteroduplexes bind dsDNA in A-like conformation.

Kisiala M, Kowalska M, Pastor M, Korza HJ, Czapinska H, Bochtler M.

Nucleic Acids Res.. 2020

The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells.

Fatima A, Irmak D, Noormohammadi A, Rinschen MM, Das A, Leidecker O, Schindler C, Sánchez-Gaya V, Wagle P, Pokrzywa W, Hoppe T, Rada-Iglesias A, Vilchez D.

Commun Biol.. 2020

In Vitro Directed Evolution of a Restriction Endonuclease With More Stringent Specificity.

Skowronek KJ, Bochtler M.

J Vis Exp . 2020

RNA-Puzzles Round IV: 3D Structure Predictions of Four Ribozymes and Two Aptamers.

Miao Z et al. (Boniecki MJ, Bujnicki JM, Joshi A, Magnus M, Piatkowski P, Pluta R.)

RNA. 2020

MetaPhOrs 2.0: Integrative, Phylogeny-Based Inference of Orthology and Paralogy Across the Tree of Life.

Chorostecki U, Molina M, Pryszcz LP, Gabaldón T.

Nucleic Acids Res.. 2020

Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition.

Lambert AR, Hallinan JP, Werther R, Głów D, Stoddard BL.

Structure. 2020

Immunoglobulin Expression and the Humoral Immune Response Is Regulated by the Non-Canonical poly(A) Polymerase TENT5C.

Bilska A, Kusio-Kobiałka M, Krawczyk PS, Gewartowska OTarkowski B, Kobyłecki K, Nowis D, Golab J, Gruchota J, Borsuk E, Dziembowski A, Mroczek S.

Nat Commun.. 2020

Vimentin S-glutathionylation at Cys328 Inhibits Filament Elongation and Induces Severing of Mature Filaments in Vitro.

Kaus-Drobek M, Mücke N, Szczepanowski RH, Wedig T, Czarnocki-Cieciura M, Polakowska M, Herrmann H, Wysłouch-Cieszyńska A, Dadlez M.

FEBS J.. 2020

Human REXO2 Controls Short Mitochondrial RNAs Generated by mtRNA Processing and Decay Machinery to Prevent Accumulation of Double-Stranded RNA.

Szewczyk M, Malik D, Borowski LS, Czarnomska SD, Kotrys AV, Klosowska-Kosicka K, Nowotny M, Szczesny RJ.

Nucleic Acids Res.. 2020

MasterOfPores: A Workflow for the Analysis of Oxford Nanopore Direct RNA Sequencing Datasets

Cozzuto L, Liu H, Pryszcz LP, Pulido TH, Delgado-Tejedor A, Ponomarenko J, Novoa EM.

Front Genet.. 2020

Dynamics, a Powerful Component of Current and Future in Silico Approaches for Protein Design and Engineering.

Surpeta B, Sequeiros-Borja CE, Brezovsky J.

Int J Mol Sci.. 2020

Origins of the increased affinity of phosphorothioate-modified therapeutic nucleic acids for proteins.

Hyjek-Składanowska M, Vickers T, Napiórkowska A, Anderson B, Tanowitz M, Crooke ST, Liang XH, Seth PP, Nowotny M.

J Am Chem Soc.. 2020

miR-7 Controls the Dopaminergic/Oligodendroglial Fate through Wnt/β-catenin Signaling Regulation.

Adusumilli L, Facchinello N, Teh C, Busolin G, Le MT, Yang H, Beffagna G, Campanaro S, Tam WL, Argenton F, Lim B, Korzh V, Tiso N.

Cells . 2020

First Evidence for STING SNP R293Q Being Protective Regarding Obesity-Associated Cardiovascular Disease in Age-Advanced Subjects - A Cohort Study.

Hamann L, Szwed M, Mossakowska M, Chudek J, Puzianowska-Kuznicka M.

Immun Ageing . 2020

Role of dynein-dynactin complex, kinesins, motor adaptors and their phosphorylation in dendritogenesis.

Tempes A, Weslawski J, Brzozowska A, Jaworski J.

J Neurochem.. 2020

RNA-Puzzles toolkit: a computational resource of RNA 3D structure benchmark datasets, structure manipulation, and evaluation tools.

Magnus M, Antczak M, Zok T, Wiedemann J, Lukasiak P, Cao Y, Bujnicki JM, Westhof E, Szachniuk M, Miao Z.

Nucleic Acids Res.. 2020

Membrane Trafficking: Vesicle Formation, Cargo Sorting and Fusion.

 Miaczynska M, Munson M.

Mol Biol Cell. . 2020

TrkB hyperactivity contributes to brain dysconnectivity, epileptogenesis, and anxiety in zebrafish model of Tuberous Sclerosis Complex.

Kedra M, Banasiak K, Kisielewska K, Wolinska-Niziol L, Jaworski J, Zmorzynska J.

Proc Natl Acad Sci U S A. . 2020

Article BioShell 3.0: Library for Processing Structural Biology Data.

Macnar JM, Szulc N, Kryś JD, Badaczewska-Dawid AE, Gront D.

Biomolecules. 2020

Arrhenius-law-governed homo- and heteroduplex dissociation.

Bochtler M.

Phys Rev E. 2020

Transgenic Mice Overexpressing Human STIM2 and ORAI1 in Neurons Exhibit Changes in Behavior and Calcium Homeostasis but Show No Signs of Neurodegeneration.

Majewski L, Maciąg F, Boguszewski PM, Kuznicki J.

Int. J. Mol. Sci.. 2020

STIM Protein-NMDA2 Receptor Interaction Decreases NMDA-Dependent Calcium Levels in Cortical Neurons.

Gruszczynska-Biegala J, Strucinska K, Maciag F, Majewski L, Sladowska M, Kuznicki J.

Cells. 2020

Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer.

Szymańska E, Nowak P, Kolmus K, Cybulska M, Goryca K, Derezińska-Wołek E, Szumera-Ciećkiewicz A, Brewińska-Olchowik M, Grochowska A, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miączyńska M.

EMBO Mol Med.. 2020

A combined structural and biochemical approach reveals translocation and stalling of UvrB on the DNA lesion as a mechanism of damage verification in bacterial nucleotide excision repair.

Jaciuk M, Swuec P, Gaur V, Kasprzak JM, Renault L, Dobrychłop M, Nirwal S, Bujnicki JM, Costa A, Nowotny M.

DNA Repair (Amst).. 2020

Ubiquitin Signaling Regulates RNA Biogenesis, Processing, and Metabolism.

Thapa P, Shanmugam N, Pokrzywa W.

BioEssays. 2020

Two-site recognition of Staphylococcus aureus peptidoglycan by lysostaphin SH3b.

Gonzalez-Delgado LS, Walters-Morgan H, Salamaga B, Robertson AJ, Hounslow AM, Jagielska E, Sabała I, Williamson MP, Lovering AL, Mesnage S.

Nat Chem Biol.. 2020

2019

Crosslink and shield: protecting abasic sites from error-prone repair.

Nowotny M.

Nat Struct Mol Biol.. 2019

Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7.

Mohanraj K, Wasilewski M, Benincá C, Cysewski D, Poznanski J, Sakowska P, Bugajska Z, Deckers M, Dennerlein S, Fernandez-Vizarra E, Rehling P, Dadlez M, Zeviani M, Chacinska A.

EMBO Mol Med.. 2019

Non-canonical translation initiation in yeast generates a cryptic pool of mitochondrial proteins.

Monteuuis G, Miścicka A, Świrski M, Zenad L, Niemitalo O, Wrobel L, Alam J, Chacinska A, Kastaniotis AJ, Kufel J.

Nucleic Acids Res.. 2019

The protein-binding N-terminal domain of human translation elongation factor 1Bβ possesses a dynamic α-helical structural organization.

Bondarchuk TV, Lozhko DM, Shalak VF, Fatalska A, Szczepanowski RH, Dadlez M,
Negrutskii BS, El'skaya AV.

Int J Biol Macromol. . 2019

Enhanced oligomerization of full-length RAGE by synergy of the interaction of its domains.

Moysa A, Hammerschmid D, Szczepanowski RH, Sobott F, Dadlez M.

Sci Rep. . 2019

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases.

Mazur M, Dymek B, Koralewski R, Sklepkiewicz P, Olejniczak S, Mazurkiewicz M, Piotrowicz M, Salamon M, Jędrzejczak K, Zagozdzon A, Czestkowski W, Matyszewski K, Borek B, Bartoszewicz A, Pluta E, Rymaszewska A, Mozga W, Stefaniak F, Dobrzański P, Dzwonek K, Golab J, Golebiowski A, Olczak J.

J Med Chem. . 2019

Improving selectivity of DNA-RNA binding zinc finger using directed evolution.

Sulej AA

BMC Res Notes. . 2019

RRMdb – an evolutionary-oriented database of RNA recognition motif sequences.

Nowacka M, Boccaletto P, Jankowska E, Jarzynka T, Bujnicki JM, Dunin-Horkawicz S.

Database. 2019

Matching tRNA modifications in humans to their known and predicted enzymes.

de Crecy-Lagard V, Boccaletto P, Mangleburg C, Sharma P, Lowe T, Leidel S, Bujnicki JM.

Nucleic Acids Res.. 2019

QRNAS: software tool for refinement of nucleic acid structures.

Stasiewicz J, Mukherjee S, Nithin C, Bujnicki JM.

BMC Struct Biol. . 2019

RNAcentral: a hub of information for non-coding RNA sequences.

The RNAcentral Consortium (Bujnicki JM, Boccaletto P)

Nucleic Acids Res. . 2019

Parathyroid hormone response to different vitamin D levels in population-based old and very-old Polish cohorts.

Wyskida M, Owczarek AJ, Chełmecka E, Szczerbowska I, Mossakowska M, Grodzicki T, Puzianowska-Kuźnicka M, Olszanecka-Glinianowicz M, Chudek J.

Exp Gerontol.. 2019

Cholesterol restricts lymphotoxin β receptor-triggered NF-κB signaling.

Banach-Orłowska M, Wyszyńska R, Pyrzyńska B, Maksymowicz M, Gołąb J, Miączyńska M.

Cell Commun Signal.. 2019

Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.

Slyvka A, Zagorskaitė E, Czapinska H, Sasnauskas G, Bochtler M.

Nucleic Acids Res.. 2019

Petri net-based model of the human DNA base excision repair pathway.

Radom M, Machnicka MA, Krwawicz J, Bujnicki JM, Formanowicz P

PLoS One. 2019

RNA 3D structure prediction guided by independent folding of homologous sequences.

Magnus M, Kappel K, Das R, Bujnicki JM

BMC Bioinformatics. 2019

Changes in Calcium Homeostasis and Gene Expression Implicated in Epilepsy in Hippocampi of Mice Overexpressing ORAI1.

Majewski L, Wojtas B, Maciąg F, Kuznicki J.

Int J Mol Sci. . 2019

Influence of Sociodemographic, Behavioral and Other Health-Related Factors on Healthy Ageing Based on Three Operative Definitions.

Pac A, Tobiasz-Adamczyk B, Błędowski P, Skalska A, Szybalska A, Zdrojewski T, Więcek A, Chudek J, Michel JP, Grodzicki T.

J Nutr Health Aging.. 2019

Obesity Paradox in Caucasian Seniors: Results of the PolSenior Study.

Puzianowska-Kuznicka M, Kuryłowicz A, Walkiewicz D, Borkowska J, Owczarz M, Olszanecka-Glinianowicz M, Wieczorowska-Tobis K, Skalska A, Szybalska A, Mossakowska M.

J Nutr Health Aging. . 2019

Restriction of mitochondrial calcium overload by mcu inactivation renders neuroprotective effect in Zebrafish models of Parkinson's disease.

Soman SK, Bazała M, Keatinge M, Bandmann O, Kuznicki J.

Biol Open.. 2019

Kv2.1 voltage‐gated potassium channels in developmental perspective.

Jędrychowska J, Korzh V.

Dev Dyn.. 2019

Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease.

Gaur V, Ziajko W, Nirwal S, Szlachcic A, Gapińska M, Nowotny M

Nucleic Acids Res.. 2019

RuvC uses dynamic probing of the Holliday junction substrate to achieve sequence specificity and efficient resolution.

Górecka KM, Krepl M, Szlachcic A, Poznański J, Šponer J, Nowotny M.

Nat Commun.. 2019

A protein architecture guided screen for modification dependent restriction endonucleases.

Lutz T, Flodman K, Copelas A, Czapinska H, Mabuchi M, Fomenkov A, He X, Bochtler M, Xu S.

Nucleic Acids Res.. 2019

Glomerular permeability is not affected by heparan sulfate glycosaminoglycan deficiency in zebrafish embryos.

Khalil R, Lalai RA, Wiweger MI, Avramut CM, Koster AJ, Spaink HP, Bruijn JA, Hogendoorn PCW, Baelde HJ.

Am J Physiol Renal Physiol.. 2019

CA125 as a Marker of Heart Failure in the Older Women: Population-Based Analysis.

Bulska-Będkowska W, Chełmecka E, Owczarek AJ, Mizia-Stec K, Witek A, Szybalska A, Grodzicki T, Olszanecka-Glinianowicz M, Chudek J.

J Clin Med. 2019

Clinical examination of peripheral arterial disease and ankle-brachial index in a nationwide cohort of older subjects: practical implications.

Królczyk J, Piotrowicz K, Chudek J, Puzianowska-Kuźnicka M, Mossakowska M, Szybalska A, Grodzicki T, Skalska A, Gąsowski J.

Aging Clin Exp Res. 2019

National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries.

NCD Risk Factor Collaboration (Mossakowska M and Ślusarczyk P)

Int J Epidemiol. 2019

RNases H: Structure and mechanism.

Hyjek M, Figiel M, Nowotny M.

DNA Repair (Amst). 2019

A novel conserved enhancer at zebrafish zic3 and zic6 loci drives neural expression.

Minhas R, Paterek A, Łapiński M, Bazała M, Korzh V, Winata CL

Dev Dyn. . 2019

Rising rural body-mass index is the main driver of the global obesity epidemic in adults.

NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M and Ślusarczyk P

Nature. 2019

Heat shock proteins create a signature to predict the clinical outcome in breast cancer.

Klimczak M, Biecek P, Zylicz A, Zylicz M.

Sci Rep. . 2019

Cytosolic translational responses differ under conditions of severe short-term and long-term mitochondrial stress.

Samluk L, Urbanska M, Kisielewska K, Mohanraj K, Kim MJ, Machnicka K, Liszewska E, Jaworski J, Chacinska A.

Mol Biol Cell.. 2019

Specific interaction of zinc finger protein Com with RNA and the crystal structure of a self-complementary RNA duplex recognized by Com.

Nowacka M, Fernandes H, Kiliszek A, Bernat A, Lach G, Bujnicki JM.

PLoS One. 2019

DNA polymerase ι is acetylated in response to SN2 alkylating agents.

McIntyre J, Sobolewska A, Fedorowicz M, McLenigan MP, Macias M, Woodgate R, Sledziewska-Gojska E.

Sci Rep.. 2019

Crystal Structure and Directed Evolution of Specificity of NlaIV Restriction Endonuclease.

Czapinska H, Siwek W, Szczepanowski RH, Bujnicki JM, Bochtler M, Skowronek KJ.

J Mol Biol.. 2019

Identification of Zebrafish Calcium Toolkit Genes and their Expression in the Brain.

Wasilewska I, Gupta RK, Palchevska O, Kuźnicki J.

Genes (Basel). 2019

Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice.

Rojek KO, Krzemień J, Doleżyczek H, Boguszewski PM, Kaczmarek L, Konopka W, Rylski M, Jaworski J, Holmgren L, Prószyński TJ.

PLoS Biol.. 2019

Structural bases of peptidoglycan recognition by lysostaphin SH3b domain.

Mitkowski P, Jagielska E, Nowak E, Bujnicki JM, Stefaniak F, Niedziałek D, Bochtler M, Sabała I.

Sci Rep.. 2019

Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.

Ahuja G et al. (Dodzian J)

EMBO Rep.. 2019

Pathological mTOR mutations impact cortical development.

Tarkowski B, Kuchcinska K, Blazejczyk M, Jaworski J.

Hum Mol Genet.. 2019

Use of renal risk drugs in a nation-wide Polish older adult population: an analysis of PolSenior database.

Deskur-Śmielecka E, Chudek J, Neumann-Podczaska A, Mossakowska M, Wizner B, Wieczorowska-Tobis K.

BMC Geriatr. . 2019

Interplay of Chimeric Mating-Type Loci Impairs Fertility Rescue and Accounts for Intra-Strain Variability in Zygosaccharomyces rouxii Interspecies Hybrid ATCC42981.

Bizzarri M, Cassanelli S, Bartolini L, Pryszcz LP, Dušková M, Sychrová H, Solieri L.

Front Genet.. 2019

Comparative transcriptome analysis reveals new molecular pathways for cucumber genes related to sex determination.

Pawełkowicz M, Pryszcz L, Skarzyńska A, Wóycicki RK, Posyniak K, Rymuszka J, Przybecki Z, Pląder W.

Plant Reprod. . 2019

Function, evolution, and structure of J-domain proteins.

Kampingaa HH et al. …. (Zylicz A, Zylicz M)

Cell Stress Chaperones.. 2019

Diverse and cancer type‑specific roles of the p53 R248Q gain‑of‑function mutation in cancer migration and invasiveness.

Olszewski MB, Pruszko M, Snaar-Jagalska E, Zylicz A, Zylicz M.

Int. J. Oncol.. 2019

Glucocorticoid receptor (NR3C1) gene polymorphisms are associated with age and blood parameters in Polish Caucasian nonagenarians and centenarians.

Olczak E, Kuryłowicz A, Wicik Z, Kołodziej P, Cąkała-Jakimowicz M, Buyanovskaya O, Ślusarczyk P, Mossakowska M, Puzianowska-Kuźnicka M.

Exp Gerontol. . 2019

Dynamics of cardiomyocyte transcriptome and chromatin landscape demarcates key events of heart development.

Pawlak M, Kedzierska KZ, Migdal M, Nahia KA, Ramilowski JA, Bugajski L, Hashimoto K, Marconi A, Piwocka K, Carninci P, Winata CL.

Genome Res.. 2019

Behavioral and electrophysiological changes in female mice overexpressing ORAI1 in neurons.

Maciąg F, Majewski Ł, Boguszewski P.M, Gupta R.K, Wasilewska I, Wojtas B, Kuznicki J.

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2019

Computational modeling of RNA 3D structure based on experimental data.

Ponce-Salvatierra A, Astha, Merdas K, Chandran N, Ghosh P, Mukherjee S, Bujnicki JM.

Biosci Rep. . 2019

GSK3β activity alleviates epileptogenesis and limits GluA1 phosphorylation.

Urbanska M⁠⁠,⁠ Kazmierska-Grebowska⁠ P, Kowalczyk⁠ T., Caban B⁠, Nader⁠ K, Pijet⁠ B, Kalita ⁠K, Gozdz⁠ A, Devijver⁠e H, Lechat⁠e B, Jaworski T⁠, Grajkowska⁠ W, Sadowski⁠ K, Jozwiak⁠ S⁠,⁠ Kotulska⁠ K, Konopacki⁠ J, Van Leuven⁠ F, van Vliet⁠h E⁠, Aronica⁠ E⁠,⁠ Jaworski⁠ J.

EBioMedicine. 2019

Polyelectrolyte Membrane Scaffold Sustains Growth of Neuronal Cells.

Grzeczkowicz A, Gruszczynska-Biegala J, Czeredys M, Kwiatkowska A, Strawski M, Szklarczyk M, Koźbiał M, Kuźnicki J, Granicka LH.

J Biomed Mater Res A.. 2019

STING SNP R293Q Is Associated with a Decreased Risk of Aging-Related Diseases.

Hamann L, Ruiz-Moreno JS, Szwed M, Mossakowska M, Lundvall L, Schumann RR, Opitz B, Puzianowska-Kuznicka M.

Gerontology.. 2019

ESCRT Proteins Control the Dendritic Morphology of Developing and Mature Hippocampal Neurons.

Firkowska M, Macias M, Jaworski J.

Mol Neurobiol.. 2019

Novel calcineurin A (PPP3CA) variant associated with epilepsy, constitutive enzyme activation and downregulation of protein expression.

Rydzanicz M, Wachowska M, Cook EC, Lisowski P, Kuźniewska B, Szymańska K, Diecke S, Prigione A, Szczałuba K, Szybińska A, Koppolu A, Murcia Pienkowski V, Kosińska J, Wiweger M, Kostrzewa G, Brzozowska M, Domańska-Pakieła D, Jurkiewicz E, Stawiński P, Gromadka A, Zielenkiewicz P, Demkow U, Dziembowska M, Kuźnicki J, Creamer TP, Płoski R.

Eur J Hum Genet.. 2019

2018

Draft Genome Sequences of the Highly Halotolerant Strain Zygosaccharomyces rouxii ATCC 42981 and the Novel Allodiploid Strain Zygosaccharomyces sapae ATB301T Obtained Using the MinION Platform.

Bizzarri M, Cassanelli S, Pryszcz LP, Gawor J, Gromadka R, Solieri L.

Microbiol Resour Announc.. 2018

nextPARS: parallel probing of RNA structures in Illumina.

Saus E, Willis JR, Pryszcz LP, Hafez A, Llorens C, Himmelbauer H, Gabaldón T.

RNA. 2018

Transcriptome Analyses of Mosaic (MSC) Mitochondrial Mutants of Cucumber in a Highly Inbred Nuclear Background.

Mróz TL, Eves-van den Akker S, Bernat A, Skarzyńska A, Pryszcz L, Olberg M, Havey MJ, Bartoszewski G.

G3 . 2018

Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase.

Figiel M, Krepl M, Park S, Poznański J, Skowronek K, Gołąb A, Ha T, Šponer J, Nowotny M.

J Biol Chem. 2018

Integration of the Endocytic System into the Network of Cellular Functions.

Budick-Harmelin N, Miaczynska M.

Prog Mol Subcell Biol.. 2018

Brain derived neutrophic factor, a link of aerobic metabolism to neuroplasticity.

De Assis GG, Gasanov EV, de Sousa MBC, Kozacz A, Murawska-Cialowicz E. Brain derived neutrophic factor, a link of aerobic metabolism to neuroplasticity.

J Physiol Pharmacol. . 2018

Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional Aβ deposition rate and plaque burden at treatment initiation.

Brendel M, Jaworska A, Overhoff F, Blume T, Probst F, Gildehaus FJ, Bartenstein P, Haass C, Bohrmann B, Herms J, Willem M, Rominger A.

Theranostics. 2018

The level of microRNA 21 is upregulated by rapamycin in serum of tuberous sclerosis complex patients and subependymal giant cell astrocytoma (SEGA)-derived cell cultures.

Kuzniewska B, Sadowski K, Urbanska K, Urbanska M, Kotulska K, Liszewska E, Grajkowska W, Jóźwiak S, Dziembowska M.

Folia Neuropathol. . 2018

Neural Stem Cell Dysfunction in Human Brain Disorders.

Liszewska E, Jaworski J.

Results Probl Cell Differ.. 2018

c-Fos and neuronal plasticity: the aftermath of Kaczmarek's theory.

Jaworski J, Kalita K, Knapska E.

Acta Neurobiol Exp (Wars). . 2018

Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase.

Mazur M, Bartoszewicz A, Dymek B, Salamon M, Andryianau G, Kowalski M, Olejniczak S, Matyszewski K, Pluta E, Borek B, Stefaniak F, Zagozdzon A, Mazurkiewicz M, Koralewski R, Czestkowski W, Piotrowicz M, Niedziejko P, Gruza MM, Dzwonek K, Golebiowski A, Golab J, Olczak J.

28(3). 2018

Shifting meiotic to mitotic spindle assembly in oocytes disrupts chromosome alignment.

Bennabi I, Quéguiner I, Kolano A, Boudier T, Mailly P, Verlhac MH, Terret ME.

EMBO Rep.. 2018

The Bacteroidetes Q-Rule: Pyroglutamate in Signal Peptidase I Substrates.

Bochtler M, Mizgalska D, Veillard F, Nowak ML, Houston J, Veith P, Reynolds EC, Potempa J.

Front Microbiol.. 2018

The OB-fold proteins of the Trypanosoma brucei editosome execute RNA-chaperone activity.

Voigt C, Dobrychlop M, Kruse E, Czerwoniec A, Kasprzak JM, Bytner P, Campo CD, Leeder WM, Bujnicki JM, Göringer HU.

Nucleic Acids Res.. 2018

Positioning Europe for the EPITRANSCRIPTOMICS challenge.

Jantsch MF et al. (Bujnicki J, Purta E)

RNA Biol.. 2018

Human RNA cap1 methyltransferase CMTr1 cooperates with RNA helicase DHX15 to modify RNAs with highly structured 5' termini.

Toczydlowska-Socha D, Zielinska MM, Kurkowska M, Astha, Almeida CF, Stefaniak F, Purta E, Bujnicki JM.

Philos Trans R Soc Lond B Biol Sci.. 2018

Phosphoproteomic insights into processes influenced by the kinase-like protein DIA1/C3orf58.

Hareza A, Bakun M, Świderska B, Dudkiewicz M, Koscielny A, Bajur A, Jaworski J, Dadlez M, Pawłowski K.

PeerJ.. 2018

Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish.

Sokol AM, Uszczynska-Ratajczak B, Collins MM, Bazala M, Topf U, Lundegaard PR, Sugunan S, Guenther S, Kuenne C, Graumann J, Chan SSL, Stainier DYR, Chacinska A.

PLoS Genet.. 2018

Unique mechanism of target recognition by PfoI restriction endonuclease of the CCGG-family.

Tamulaitiene G, Manakova E, Jovaisaite V, Tamulaitis G, Grazulis S, Bochtler M, Siksnys V.

Nucleic Acids Res.. 2018

Specificity of MLL1 and TET3 CXXC domains towards naturally occurring cytosine modifications.

Stroynowska-Czerwinska A, Piasecka A, Bochtler M.

Biochim Biophys Acta Gene Regul Mech.. 2018

Possible association of the TERT promoter polymorphisms rs2735940, rs7712562 and rs2853669 with diabetes mellitus in obese elderly Polish population: results from the national PolSenior study.

Gutmajster E, Chudek J, Augusciak-Duma A, Szwed M, Szybalska A, Mossakowska M, Puzianowska-Kuznicka M, Wiecek A, Sieron AL.

J Appl Genet. . 2018

Atrial fibrillation independently linked with depression in communitydwelling older population. Results from the nationwide PolSenior project.

Rewiuk K, Wizner B, Klich-Rączka A, Więcek A, Mossakowska M, Chudek J, Szybalska A, Broczek K, Zdrojewski T, Grodzicki T.

Exp Gerontol. . 2018

Zebrafish Zic Genes Mediate Developmental Signaling.

 

Winata CL, Korzh V.

Adv Exp Med Biol. . 2018

Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins.

Kowalski L, Bragoszewski P, Khmelinskii A, Glow E, Knop M, Chacinska A.

BMC Biol. . 2018

Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species.

Topf U, Suppanz I, Samluk L, Wrobel L, Böser A, Sakowska P, Knapp B, Pietrzyk MK, Chacinska A, Warscheid B.

Nat Commun. . 2018

The topology of lymphotoxin β receptor accumulated upon endolysosomal dysfunction dictates the NF-κB signaling outcome.

Banach-Orłowska M, Jastrzębski K, Cendrowski JMaksymowicz M, Wojciechowska K, Korostyński M, Moreau D, Gruenberg J, Miaczynska M.

J Cell Sci.. 2018

Huntingtin-Associated Protein 1A Regulates Store-Operated Calcium Entry in Medium Spiny Neurons From Transgenic YAC128 Mice, a Model of Huntington’s Disease.

Czeredys M, Vigont VA, Boeva VA, Mikoshiba K, Kaznacheyeva EV, Kuznicki J.

Front Cell Neurosci.. 2018

Crystal structure of human Acinus RNA recognition motif domain.

Fernandes H, Czapinska H, Grudziaz K, Bujnicki JM, Nowacka M.

PeerJ.. 2018

Bioinformatics Tools and Benchmarks for Computational Docking and 3D Structure Prediction of RNA-Protein Complexes.

Nithin C, Ghosh P, Bujnicki JM.

Genes (Basel). 2018

Prevalence of anemia in relation to socio-economic factors in elderly Polish population: the results of PolSenior study.

Styszynski A, Mossakowska M, Chudek J, Puzianowska-Kuznicka M, Klich-Raczka A, Neumann-Podczaska A, Szybalska A, Wieczorowska-Tobis K.

J Physiol Pharmacol.. 2018

Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanism.

Walerych D, Pruszko M, Zyla L, Wezyk M, Gaweda-Walerych K, Zylicz A.

Oncotarget. 2018

Dental status in the Polish senior population and its correlates-Results of the national survey PolSenior.

Mehr K, Olszanecka-Glinianowicz M, Chudek J, Szybalska A, Mossakowska M, Zejda J, Wieczorowska-Tobis K, Grodzicki T, Piotrowski P.

Gerodontology. 2018

Crystal structure of the modification-dependent SRA-HNH endonuclease TagI

Kisiala M, Copelas A, Czapinska H, Xu S, Bochtler M.

Nucleic Acids Res.. 2018

Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.

Kumari P, Aeschimann F, Gaidatzis D, Keusch JJ, Ghosh P, Neagu A, Pachulska-Wieczorek K, Bujnicki JM, Gut H, Großhans H, Ciosk R.

Nat Commun.. 2018

Novel inhibitors of the rRNA ErmC' methyltransferase to block resistance to macrolides, lincosamides, streptogramine B antibiotics.

Foik IP, Tuszynska I, Feder M, Purta E, Stefaniak F, Bujnicki JM.

Eur J Med Chem.. 2018

Activity and structure of EcoKMcrA.

Czapinska H, Kowalska M, Zagorskaite E, Manakova E, Slyvka A, Xu SY, Siksnys V, Sasnauskas G, Bochtler M.

Nucleic Acids Res.. 2018

Antisense and yet sensitive: Copy number control of rolling circle-replicating plasmids by small RNAs.

Pluta R, Espinosa M.

Wiley Interdiscip Rev RNA. 2018

Self-rated health and its association with all-cause mortality of older adults in Poland: The PolSenior project.

Szybalska A, Broczek K, Puzianowska-Kuznicka M, Slusarczyk P, Chudek J, Skalska A, Mossakowska M.

Arch Gerontol Geriatr.. 2018

Neuronal calcium signaling via store-operated channels in health and disease.

Wegierski T, Kuznicki J.

Cell Calcium.. 2018

The translational regulation of maternal mRNAs in time and space.

Winata CL, Korzh V.

FEBS Lett. . 2018

The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients.

Koyuncu S, Saez I, Lee HJ, Gutierrez-Garcia R, Pokrzywa W, Fatima A, Hoppe T, Vilchez D.

Nat Commun.. 2018

Plasma concentration of Retinol Binding Protein 4 (RBP4) in relation to nutritional status and kidney function in older population of PolSenior Study.

Kocełak P, Owczarek A, Bożentowicz-Wikarek M, Brzozowska A, Mossakowska M, Grodzicki T, Więcek A, Chudek J, Olszanecka-Glinianowicz M.

Adv Med Sci.. 2018

Plasma Level of Retinol-Binding Protein 4, N-Terminal proBNP and Renal Function in Older Patients Hospitalized for Heart Failure.

Majerczyk M, Choręza P, Mizia-Stec K, Bożentowicz-Wikarek M, Brzozowska A, Arabzada H, Owczarek AJ, Szybalska A, Grodzicki T, Więcek A, Olszanecka-Glinianowicz M, Chudek J.

Cardiorenal Med.. 2018

Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages.

Donzelli S, Milano E, Pruszko M, Sacconi A, Masciarelli S, Iosue I, Melucci E, Gallo E, Terrenato I, Mottolese M, Zylicz M, Zylicz A, Fazi F, Blandino G, Fontemaggi G.

Breast Cancer Res.. 2018

Utilization of medical rehabilitation services among older Poles: results of the PolSenior study.

Szybalska A, Broczek K, Slusarczyk P, Kozdron, Chudek J, Puzianowska‑Kuznicka M, Kostka T, Skalska A, Mossakowska M.

Eur Geriatr Med.. 2018

Decoding the Heart through Next Generation Sequencing Approaches.

Pawlak M, Niescierowicz K, Winata CL.

Genes (Basel). . 2018

SIRT1, miR-132 and miR-212 link human longevity to Alzheimer's Disease.

Hadar A, Milanesi E, Walczak M, Puzianowska-Kuźnicka M, Kuźnicki J, Squassina A, Niola P, Chillotti C, Attems J, Gozes I, Gurwitz D.

Sci Rep.. 2018

CAVER Analyst 2.0: Analysis and Visualization of Channels and Tunnels in Protein Structures and Molecular Dynamics Trajectories.

Jurcik A, Bednar D, Byska J, Marques SM, Furmanova K, Daniel L, Kokkonen P, Brezovsky J, Strnad O, Stourac J, Pavelka A, Manak M, Damborsky J, Kozlikova B.

Bioinformatics. 2018

5′-Phosphorothiolate Dinucleotide Cap Analogues: Reagents for Messenger RNA Modification and Potent Small-Molecular Inhibitors of Decapping Enzymes.

Wojtczak BA, Sikorski PJ, Fac-Dabrowska K, Nowicka A, Warminski M, Kubacka D, Nowak E, Nowotny M, Kowalska J, Jemielity J.

J Am Chem Soc.. 2018

A Protocol for Laboratory Housing of Turquoise Killifish (Nothobranchius furzeri).

Dodzian J, Kean S, Seidel J, Valenzano DR.

Journal of Visualized Experiments (JoVE). 2018

Quality of life related to oral, subcutaneous, and intravenous biologic treatment of inflammatory bowel disease: a time trade-off study.

Holko P, Kawalec P, Mossakowska M.

J Gastroenterol Hepatol. 2018

Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants.

NCD Risk Factor Collaboration (Mossakowska M and Slusarczyk P)

Int J Epidemiol. . 2018

The utilization of health resort treatment services by older people in Poland – results of the PolSenior study.

Szybalska A, Broczek K, Ślusarczyk P, Kozdroń E, Błędowski P, Chudek J, Mossakowska M.

Gerontologia Polska. 2018

Ubiquitylation Pathways In Insulin Signaling and Organismal Homeostasis.

Balaji V, Pokrzywa W, Hoppe T.

Bioessays. 2018

Chaperoning the guardian of the genome. The two-faced role of molecular chaperones in p53 tumor suppressor action.

Wawrzynow B, Zylicz A, Zylicz M.

BBA-Rev Cancer. 2018

Components of metabolic syndrome in relation to plasma levels of retinol binding protein 4 (RBP4) in a cohort of people aged 65 years and older.

Majerczyk M, Kocełak P, Choręza P, Arabzada H, Owczarek AJ, Bożentowicz-Wikarek M, Brzozowska A, Szybalska A, Puzianowska-Kuźnicka M, Grodzicki T, Więcek A, Olszanecka-Glinianowicz M, Chudek J.

J Endocrinol Invest.. 2018

The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers.

Piasecka A, Czapinska H, Vielberg MT, Szczepanowski RH, Kiefersauer R, Reed S, Groll M, Bochtler M.

J Mol Biol.. 2018

MODOMICS: a database of RNA modification pathways. 2017 update.

Boccaletto P, Machnicka MA, Purta E, Piatkowski P, Baginski B, Wirecki TK, de Crécy-Lagard V, Ross R, Limbach PA, Kotter A, Helm M, Bujnicki JM.

Nucleic Acids Res.. 2018

Socio-economic determinants of vitamin D deficiency in the older Polish population: results from the PolSenior study.

Wyskida M, Owczarek A, Szybalska A, Brzozowska A, Szczerbowska I, Wieczorowska-Tobis K, Puzianowska-Kuźnicka M, Franek E, Mossakowska M, Grodzicki T, Więcek A, Olszanecka-Glinianowicz M, Chudek J.

Public Health Nutr.. 2018

Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components.

Razew M, Warkocki Z, Taube M, Kolondra A, Czarnocki-Cieciura M, Nowak E, Labedzka-Dmoch K, Kawinska A, Piatkowski J, Golik P, Kozak M, Dziembowski A, Nowotny M.

Nat Commun.. 2018

Health status of older cancer survivors—results of the PolSenior study.

Sulicka J, Pac A, Puzianowska-Kuźnicka M, Zdrojewski T, Chudek J, Tobiasz-Adamczyk B, Mossakowska M, Skalska A, Więcek A, Grodzicki T.

Journal of Cancer Survivorship. 2018

Cytoplasmic polyadenylation-mediated translational control of maternal mRNAs directs maternal to zygotic transition.

Winata CL, Łapiński M, Pryszcz L, Vaz C, Bin Ismail MH, Nama S, Hajan HS, Lee SGP, Korzh V, Sampath P, Tanavde V, Mathavan S.

Development.. 2018

Novel role for the testis-enriched HSPA2 protein in regulating epidermal keratinocyte differentiation.

Gogler-Pigłowska A, Klarzyńska K, Sojka DR, Habryka A, Głowala-Kosińska M, Herok M, Kryj M, Halczok M, Krawczyk Z, Scieglinska D.

J Cell Physiol.. 2018

GSK3β Controls mTOR and Prosurvival Signaling in Neurons.

Urbanska M, Gozdz A, Macias M, Cymerman IA, Liszewska E, Kondratiuk I, Devijver H, Lechat B, Van Leuven F, Jaworski J.

Mol Neurobiol.. 2018

RNArchitecture: a database and a classification system of RNA families, with a focus on structural information.

Boccaletto P, Magnus M, Almeida C, Zyla A, Astha A, Pluta R, Baginski B, Jankowska E, Dunin-Horkawicz S, Wirecki TK, Boniecki MJ, Stefaniak F, Bujnicki JM.

Nucleic Acids Res.. 2018

Development of brain ventricular system

Korzh V

Cell Mol Life Sci. 2018

Blocking c-Fos Expression Reveals the Role of Auditory Cortex Plasticity in Sound Frequency Discrimination Learning

de Hoz L, Gierej D, Lioudyno V, Jaworski J, Blazejczyk M, Cruces-Solís H, Beroun A, Lebitko T, Nikolaev T, Knapska E, Nelken I, Kaczmarek L

Cereb Cortex. 2018

Adaptor Complex 2 Controls Dendrite Morphology via mTOR-Dependent Expression of GluA2

Koscielny A, Malik AR, Liszewska E, Zmorzynska J, Tempes A, Tarkowski B, Jaworski J

Mol Neurobiol. 2018

2017

Tight junction protein ZO-1 controls organic cation/carnitine transporter OCTN2 (SLC22A5) in a protein kinase C-dependent way.

Jurkiewicz  D, Michalec  K, Skowronek  K, Nałęcz  KA.

Biochim Biophys Acta Mol Cell Res.. 2017

Development of Circumventricular Organs in the Mirror of Zebrafish Enhancer-Trap Transgenics.

García-Lecea M, Gasanov E, Jedrychowska J, Kondrychyn I, Teh C, You MS, Korzh V.

Front Neuroanat. . 2017

ZnO@Gd2O3 core/shell nanoparticles for biomedical applications: Physicochemical, in vitro and in vivo characterization.

Woźniak A, Grześkowiak BF, Babayevska N, Zalewski T, Drobna M, Woźniak-Budych M, Wiweger M, Słomski R, Jurga S.

Mater Sci Eng C Mater Biol Appl. . 2017

Nei-like 1 (NEIL1) excises 5-carboxylcytosine directly and stimulates TDG-mediated 5-formyl and 5-carboxylcytosine excision.

Slyvka A, Mierzejewska K, Bochtler M.

Sci Rep.. 2017

Mikroskopowe obrazowanie jonów wapnia za pomocą genetycznie kodowanych sond (Microscopic imaging of calcium ions with genetically encoded calcium indicators).

Gazda K, Bazała M, Węgierski T.

Postepy Biochem.. 2017

Impact of the structural integrity of the three-way junction of adenovirus VAI RNA on PKR inhibition.

Dzananovic E, Astha, Chojnowski G, Deo S, Booy EP, Padilla-Meier P, McEleney K, Bujnicki JM, Patel TR, McKenna SA.

PLoS One. 2017

Occurrence and stability of lone pair-π stacking interactions between ribose and nucleobases in functional RNAs.

Chawla M, Chermak E, Zhang Q, Bujnicki JM, Oliva R, Cavallo L.

Nucleic Acids Res.. 2017

SupeRNAlign: a new tool for flexible superposition of homologous RNA structures and inference of accurate structure-based sequence alignments.

Piątkowski P, Jabłońska J, Żyła A, Niedziałek, Matelska D, Jankowska E, Waleń T, Dawson WK, Bujnicki JM.

Nucleic Acids Res.. 2017

PET/CT evaluation of 18F-FDG uptake in pericoronary adipose tissue in patients with stable coronary artery disease: Independent predictor of atherosclerotic lesions' formation?

Mazurek T, Kobylecka M, Zielenkiewicz M, Kurek A, Kochman J, Filipiak KJ, Mazurek K, Huczek Z, Królicki L, Opolski G.

J Nucl Cardiol. 2017

Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study.

Brendel M, Focke C, Blume T, Peters F, Deussing M, Probst F, Jaworska A, Overhoff F, Albert N, Lindner S, von Ungern-Sternberg B, Bartenstein P, Haass C, Kleinberger G, Herms J, Rominger A.

J Nucl Med.. 2017

Overexpression of STIM1 in neurons in mouse brain improves contextual learning and impairs long-term depression.

Majewski Ł, Maciąg F, Boguszewski PM, Wasilewska I, Wiera G, Wójtowicz T, Mozrzymas J, Kuznicki J.

Biochim Biophys Acta. 2017

Visualization of cytosolic ribosomes on the surface of mitochondria by electron cryo-tomography.

Gold VA, Chroscicki P, Bragoszewski P, Chacinska A.

EMBO Rep.. 2017

Endosomal "sort" of signaling control: The role of ESCRT machinery in regulation of receptor-mediated signaling pathways.

Szymanska E, Budick-Harmelin N, Miaczynska M.

Semin Cell Dev Biol.. 2017

Quality of life related to oral, subcutaneous, and intravenous biologic treatment of inflammatory bowel disease: a time trade-off study.

Holko P, Kawalec P, Mossakowska M.

Eur J Gastroenterol Hepatol.. 2017

Knockdown of amyloid precursor protein increases calcium levels in the endoplasmic reticulum.

Gazda K, Kuznicki J, Wegierski T.

Sci Rep. 2017

CHIPped balance of proteostasis and longevity.

Pokrzywa W, Hoppe T.

Oncotarget. 2017

Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults.

NCD Risk Factor Collaboration (NCD-RisC) within Mossakowska M & Slusarczyk P.

Lancet. 2017

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

Pasricha SR, Lim PJ, Duarte TL, Casu C, Oosterhuis D, Mleczko-Sanecka K, Suciu M, Da Silva AR, Al-Hourani K, Arezes J, McHugh K, Gooding S, Frost JN, Wray K, Santos A, Porto G, Repapi E, Gray N, Draper SJ, Ashley N, Soilleux E, Olinga P, Muckenthaler MU, Hughes JR, Rivella S, Milne TA, Armitage AE, Drakesmith H.

Nat Commun. 2017

The canonical way to make a heart: β-catenin and plakoglobin in heart development and remodeling

Piven OO, Winata CL

Experimental Biology and Medicine. 2017

The siRNA suppressor RTL1 is redox-regulated through glutathionylation of a conserved cysteine in the double-stranded-RNA-binding domain.

Charbonnel C, Niazi AK, Elvira-Matelot E, Nowak E, Zytnicki M, de Bures A, Jobet E, Opsomer A, Shamandi N, Nowotny M, Carapito C, Reichheld J-P, Vaucheret H, Saez-Vasquez J.

Nucleic Acids Res.. 2017

mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.

Rydzik AM, Warminski M, Sikorski PJ, Baranowski MR, Walczak S, Kowalska J, Zuberek J, Lukaszewicz M, Nowak E, W Claridge TD, Darzynkiewicz E, Nowotny M, Jemielity J.

Nucleic Acids Res.. 2017

mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.

Rydzik AM, Warminski M, Sikorski PJ, Baranowski MR, Walczak S, Kowalska J, Zuberek J, Lukaszewicz M, Nowak E, W Claridge TD, Darzynkiewicz E, Nowotny M, Jemielity J.

Nucleic Acids Res.. 2017

P53 Dysfunction in Neurodegenerative Diseases – The Cause or Effect of Pathological Changes?

Szybinska A, Lesniak W

Aging Dis.. 2017

Antiplatelet and anticoagulant therapy in elderly people with type 2 diabetes mellitus in Poland (based on the PolSenior Study)

Łabuz-Roszak B, Machowska-Majchrzak A, Skrzypek M, Mossakowska M, Chudek J, Więcek A, Wawrzyńczyk M, Łącka-Gaździk B, Pierzchała K

Arch Med Sci. 2017

Ikk2 regulates cytokinesis during vertebrate development

Shen H, Shin EM, Lee S, Mathavan S, Koh H, Osato M, Choi H, Tergaonkar V, Korzh V

Sci Rep. 2017

Chapter Six - Structural Studies of RNases H2 as an Example of Crystal Structure Determination of Protein–Nucleic Acid Complexes

Figiel M, Nowotny M

Methods in Enzymology. 2017

Coordination between the polymerase and RNase H activity of HIV-1 reverse transcriptase

Figiel M, Krepl M, Poznanski J, Golab A, Šponer J, Nowotny M

Nucleic Acids Res.. 2017

Chaperone-directed ubiquitylation maintains proteostasis at the expense of longevity.

Pokrzywa W, Lorenz R, Hoppe T

Worm. 2017

Pharmacological stroke prevention in the elderly with atrial fibrillation in Poland - Results of PolSenior study

Łabuz-Roszak B, Skrzypek M, Machowska-Majchrzak A, Mossakowska M, Chudek J, Więcek A, Pierzchała K, Łącka-Gaździk B, Grodzicki T

Neurol Neurochir Pol. 2017

TRIM28 epigenetic corepressor is indispensable for stable induced pluripotent stem cell formation

Klimczak M, Czerwińska P, Mazurek S, Sozańska B, Biecek P, Mackiewicz A, Wiznerowicz M

Stem Cell Research. 2017

Imatinib and spironolactone suppress hepcidin expression

Mleczko-Sanecka K, da Silva AR, Call D, Neves J, Schmeer N, Damm G, Seehofer D, Muckenthaler MU

Haematologica. 2017

GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation

Gozdz A, Nikolaienko O, Urbanska M, Cymerman IA, Sitkiewicz E, Blazejczyk M, Dadlez M, Bramham CR, Jaworski J

Front Mol Neurosci. 2017

Repair or Destruction: An Intimate Liaison Between Ubiquitin Ligases and Molecular Chaperones in Proteostasis

Kevei É, Pokrzywa W, Hoppe T

FEBS Lett. doi:10.1002/1873-3468.12750.. 2017

Identification of a Na+/K+-ATPase inhibition-independent proarrhythmic ionic mechanisms of cardiac glycosides

Koh CH, Wu J, Chung YY, Liu Z, Zhang RR, Chong K, Korzh V, Ting S, Oh S, Shim W, Tian HY, Wei H

Sci Rep.. 2017

Responsive mesoporous silica nanoparticles for sensing of hydrogen peroxide and simultaneous treatment toward heart failure

Tan SY, Teh C, Ang CY, Li M, Li P, Korzh V, Zhao Y

Nanoscale. 2017

miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans

Owczarz M, Budzinska M, Domaszewska-Szostek A, Borkowska J, Polosak J, Gewartowska M, Slusarczyk P, Puzianowska-Kuznicka M

Experimental Biology and Medicine. 2017

Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation

Tracz-Gaszewska Z, Klimczak M, Biecek P, Herok M, Kosinski M, Olszewski MB, Czerwińska P, Wiech M, Wiznerowicz M, Zylicz A, Zylicz M, Wawrzynow B

Oncotarget. 2017

The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1

Pruszko M, Milano E, Forcato M, Donzelli S, Ganci F, Di Agostino S, De Panfilis S, Fazi F, Bates DO, Bicciato S, Zylicz M, Zylicz A, Blandino G, Fontemaggi G

EMBO Rep. 2017

Mutations in human AID differentially affect its ability to deaminate cytidine and 5-methylcytidine in ssDNA substrates in vitro

Budzko L, Jackowiak P, Kamel K, Sarzynska J, Bujnicki JM, Figlerowicz M

Sci Rep. 2017

Defining the crucial domain and amino acid residues in bacterial Lon protease for DNA binding and processing of DNA-interacting substrates

Karlowicz A, Wegrzyn K, Gross M, Kaczynska D, Ropelewska M, Siemiątkowska M, Bujnicki JM, Konieczny I

J Biol Chem. 2017

RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme

Miao Z, Adamiak RW, Antczak M, Batey RT, Becka A, Biesiada M, Boniecki MJ, Bujnicki JM, Chen S, Cheng CY, Chou F, Ferré-D'Amaré AR, Das R, Dawson WK, Ding F, Dokholyan NV, Dunin-Horkawicz S, Geniesse C, Kappel K, Kladwang W, Krokhotin A, Lach GE, Major F, Mann TH, Magnus M, Pachulska-Wieczorek K, Patel DJ, Piccirilli JA, Popenda M, Purzycka KJ, Ren A, Rice GM, Santalucia J Jr, Sarzynska J, Szachniuk M, Tandon A, Trausch JJ, Tian S, Wang J, Weeks KM, Williams B II, Xiao Y, Xu X, Zhang D, Zok T, Westhof E

RNA. 2017

ZBP1 phosphorylation at serine 181 regulates its dendritic transport and the development of dendritic trees of hippocampal neurons

Urbanska AS, Janusz-Kaminska A, Switon K, Hawthorne AL, Perycz M, Urbanska M, Bassell GJ, Jaworski J

Sci Rep. 2017

Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration

Kononenko NL, Claßen GA, Kuijpers M, Puchkov D, Maritzen T, Tempes A, Malik AR, Skalecka A, Bera S, Jaworski J, Haucke V

Nat Commun. 2017

Cell biology: Sort and destroy

Chacinska A.

Nature. 2017

Control of mitochondrial biogenesis and function by the ubiquitin-proteasome system

Bragoszewski P, Turek M, Chacinska A.

Open Biol. 2017

Personalized genome sequencing coupled with iPSC technology identifies GTDC1 as a gene involved in neurodevelopmental disorders

Aksoy I, Utami KH, Winata CL, Hillmer AM, Rouam SL, Briault S, Davila S, Stanton LW, Cacheux V

Hum Mol Genet. 2017

Disease activity, quality of life, and indirect costs of ulcerative colitis in Poland

Kawalec P, Stawowczyk E, Mossakowska M, Pilc A

Prz Gastroenterol. 2017

Profile of 6 microRNA in blood plasma distinguish early stage Alzheimer's disease patients from non-demented subjects

Nagaraj S, Laskowska-Kaszub K, Dębski KJ, Wojsiat J, Dąbrowski M, Gabryelewicz T, Kuźnicki J, Wojda U

Oncotarget. 2017

Increase of TREM2 during Aging of an Alzheimer’s Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis

Brendel M, Kleinberger G, Probst F, Jaworska A, Overhoff F, Blume T, Albert NL, Carlsen J, Lindner S, Gildehaus FJ, Ozmen L, Suárez-Calvet M, Bartenstein P, Baumann K, Ewers M, Herms J, Haass C, Rominger A

Front. Aging Neurosci.. 2017

Increased plasma RBP4 concentration in older hypertensives is related to the decreased kidney function and the number of antihypertensive drugs-results from the PolSenior substudy

Majerczyk M, Choręza P, Bożentowicz-Wikarek M, Brzozowska A, Arabzada H, Owczarek A, Mossakowska M, Grodzicki T, Zdrojewski T, Więcek A, Olszanecka-Glinianowicz M, Chudek J

J Am Soc Hypertens. 2017

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

NCD Risk Factor Collaboration (Mossakowska M and Slusarczyk P)

Lancet. 2017

Multiple routes of endocytic internalization of PDGFRβ contribute to PDGF-induced STAT3 signaling

Jastrzębski K, Zdżalik-Bielecka D, Mamińska A, Kalaidzidis Y, Hellberg C, Miaczynska M

J Cell Sci.. 2017

Molecular neurobiology of mTOR

Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J

Neuroscience. 2017

A TALE-inspired computational screen for proteins that contain approximate tandem repeats.

Perycz M, Krwawicz J, Bochtler M.

PLoS One. 2017

Structural studies of RNA-protein complexes: A hybrid approach involving hydrodynamics, scattering and computational methods

Patel T, Chojnowski G, Astha, Koul A, McKenna S, Bujnicki JM

Methods. 2017

Inhibition of the mitochondrial calcium uniporter (MCU) rescues dopaminergic neurons in pink1-/- zebrafish

Soman S, Keatinge M, Moein M, DaCosta M, Mortiboys H, Skupin A, Sugunan S, Bazala M, Kuznicki J, Bandmann O

Eur J Neurosci.. 2017

TCF7L2 mediates the cellular and behavioral response to chronic lithium treatment in animal models

Misztal K, Brozko N, Nagalski A, Szewczyk LM, Królak M, Brzozowska K, Kuznicki J, Wisniewska MB

Neuropharmacology. 2017

PPARs PL

Gross B, Pawlak M, Lefebvre P, Staels B.

Nat Rev Endocrinol TEST. 2017

Tetrahydrocarbazoles decrease elevated SOCE in medium spiny neurons from transgenic YAC128 mice, a model of Huntington's disease

Czeredys M, Maciag F, Methner A, Kuznicki J

Biochem Biophys Res Commun. 2017

ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons

Szewczyk LM, Brozko N, Nagalski A, Rӧckle I, Werneburg S, Hildebrandt H, Wisniewska MB, Kuznicki J free access

Glia. 2017

Kainic Acid Induces mTORC1-Dependent Expression of Elmo1 in Hippocampal Neurons

Blazejczyk M, Macias M, Korostynski M, Firkowska M, Piechota M, Skalecka A, Tempes A, Koscielny A, Urbanska M, Przewlocki R, Jaworski J

Mol Neurobiol. 2017

GSK-3β and MMP-9 Cooperate in the Control of Dendritic Spine Morphology

Kondratiuk I, Łęski S, Urbańska M, Biecek P, Devijver H, Lechat B, Van Leuven F, Kaczmarek L, Jaworski T

Mol Neurobiol. 2017

2016

In-silico driven engineering of enantioselectivity of a penicillin G acylase towards active pharmaceutical ingredients.

Grulich M, Brezovský J, Štěpánek V, Palyzová A, Marešová H, Zahradník J, Kyslíková E, Kyslík P.

J Mol Catal B Enzym. 2016

Sequence-specific endoribonucleases.

Głów D, Nowacka M, Skowronek KJ, Bujnicki JM.

Postępy Biochemii. 2016

Okiem ryby - nowe spojrzenie na rozwój sieci neuronalnych i choroby neurorozwojowe.

Kędra M, Jaworski J, Zmorzyńska J.

Wszechświat . 2016

Danio pręgowany jako organizm modelowy.

Olszewski M, Pruszko M.

Wszechświat. 2016

Białka z rodziny ID w inicjacji i progresji nowotworów (Białka z rodziny ID w inicjacji i progresji nowotworów).

Pruszko M, Żylicz A.

Postępy Biochemii. 2016

Be Healthy as a Fish Educational Program at the International Institute of Molecular and Cell Biology in Warsaw, Poland.

Goś D, Szymańska E, Białek-Wyrzykowska U, Wiweger M, Kuźnicki J.

Zebrafish. 2016

Health-Related Quality of Life Impairment and Indirect Cost of Crohn's Disease: A Self-Report Study in Poland

Holko P, Kawalec P, Mossakowska M, Pilc A

PLoS One. 2016

Coarse-grained modeling of RNA 3D structure

Dawson WK, Maciejczyk M, Jankowska EJ, Bujnicki JM

Methods. 2016

tRNAmodpred: A computational method for predicting posttranscriptional modifications in tRNAs

Machnicka MA, Dunin-Horkawicz S, de Crécy-Lagard V, Bujnicki JM

Methods. 2016

Asymmetric DNA methylation by dimeric EcoP15I DNA methyltransferase

Urulangodi M, Dhanaraju R, Gupta K, Roy RP, Bujnicki JM, Rao DN

Biochimie. 2016

MQAPsingle: A quasi single-model approach for estimation of the quality of individual protein structure models

Pawlowski M, Kozlowski L, Kloczkowski A

Proteins. 2016

Molecularly Imprinted Polymer (MIP) Film with Improved Surface Area Developed by Using Metal-Organic Framework (MOF) for Sensitive Lipocalin (NGAL) Determination.

Iskierko Z, Sharma PS, Prochowicz D, Fronc K, D'Souza F, Toczydłowska D, Stefaniak F, Noworyta K

ACS Appl Mater Interfaces.. 2016

Identification of protein structural elements responsible for the diversity of sequence preferences among Mini-III RNases.

Glow D, Kurkowska M, Czarnecka J, Szczepaniak K, Pianka D, Kappert V, Bujnicki JM, Skowronek KJ

Sci Rep.. 2016

A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans

Kalisiak K, Kuliński TM, Tomecki R, Cysewski D, Pietras Z, Chlebowski A, Kowalska K, Dziembowski A

Nucleic Acids Res. 2016

Health status correlates of malnutrition in the polish elderly population - Results of the Polsenior Study

Krzyminska-Siemaszko R, Chudek J, Suwalska A, Lewandowicz M, Mossakowska M, Kroll-Balcerzak R, Wizner B, Tobis S, Mehr K, Wieczorowska-Tobis K

Eur Rev Med Pharmacol Sci. 2016

miR-96, miR-145 and miR-9 expression increases, and IGF-1R and FOXO1 expression decreases in peripheral blood mononuclear cells of aging humans

Budzinska M, Owczarz M, Pawlik-Pachucka E, Roszkowska-Gancarz M , Slusarczyk P, Puzianowska-Kuznicka M

BMC Geriatr. 2016

A century of trends in adult human height

NCD Risk Factor Collaboration (793 Collaborators within M. Mossakowska and P. Ślusarczyk)

Elife. 2016

In-silico driven engineering of enantioselectivity of a penicillin G acylase towards active pharmaceutical ingredients

Grulich M, Brezovský J, Štěpánek V, Palyzová A, Marešová H, Zahradník J, Kyslíková E, Kyslík P

J Mol Catal B-Enzym. 2016

Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes

Tudek B, Zdżalik-Bielecka D, Tudek A, Kosicki K, Fabisiewicz A, Speina E

Free Radic Biol Med. 2016

DNA demethylation pathways: Additional players and regulators

Bochtler M, Kolano A, Xu G-L

Bioessays. 2016

miR-132 Regulates Dendritic Spine Structure by Direct Targeting of Matrix Metalloproteinase 9 mRNA

Jasińska M, Miłek J, Cymerman IA, Łęski S, Kaczmarek L, Dziembowska M

Mol Neurobiol.. 2016

Type III CRISPR complexes from Thermus thermophilus

Szychowska M, Siwek W, Pawolski D, Kazrani AA, Pyrc K, Bochtler M

Acta Biochim Pol. 2016

Protein trafficking at the crossroads to mitochondria

Wasilewski M, Chojnacka K, Chacinska A

Biochim Biophys Acta. 2016

Białka mitochondrialne – import, eksport, degradacja

Wasilewski M, Chojnacka K, Chacinska A

Postępy Biochemii. 2016

Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli

Stracy M, Jaciuk M, Uphoff S, Kapanidis AN, Nowotny M, Sherratt DJ, Zawadzki P

Nat Commun.. 2016

Clustering of geriatric deficits emerges to be an essential feature of ageing - results of a cross-sectional study in Poland

Piotrowicz K, Pac A, Skalska AB, Chudek J, Klich-Rączka A, Szybalska A, Michel JP, Grodzicki T

Aging (Albany NY). 2016

Pseudoloma neurophilia (Microsporidia) – poważne zagrożenie dla hodowli laboratoryjnej danio pręgowanego (Danio rerio, Hamilton 1822)

Korzeniowski P, Wiweger M.

Życie Weterynaryjne. 2016

Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches

Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J

IUBMB Life. 2016

AMPA Receptors Are Involved in Store-Operated Calcium Entry and Interact with STIM Proteins in Rat Primary Cortical Neurons

Gruszczynska-Biegala J, Sladowska M, Kuznicki J

Frontiers in Cellular Neuroscience. 2016

Associations between cardiovascular disease risk factors and IL-6 and hsCRP levels in the elderly

Nadrowski P, Chudek J, Skrzypek M, Puzianowska-Kuźnicka M, Mossakowska M, Więcek A, Zdrojewski T, Grodzicki T, Kozakiewicz K

Exp Gerontol. 2016

TIM29 is a subunit of the human carrier translocase required for protein transport

Callegari S, Richter F, Chojnacka K, Jans DC, Lorenzi I, Pacheu-Grau D, Jakobs S, Lenz C, Urlaub H, Dudek J, Chacinska A, Rehling P

FEBS Lett. 2016

Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.

Mikula M, Skrzypczak M, Goryca K, Paczkowska K, Ledwon JK, Statkiewicz M, Kulecka M, Grzelak M, Dabrowska M, Kuklinska U, Karczmarski J, Rumienczyk I, Jastrzebski K, Miaczynska M, Ginalski K, Bomsztyk K, Ostrowski J.

Nucleic Acids Res. 2016

Microscopic analysis of Orai-mediated store-operated calcium entry in cells with experimentally altered levels of amyloid precursor protein

Wegierski T, Gazda K, Kuznicki J

Biochem Biophys Res Commun. 2016

Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue

Van Laer B, Roovers M, Wauters L, Kasprzak JM, Dyzma M, Deyaert E, Singh R, Feller A, Bujnicki JM, Droogmans L, Versées W

Nucleic Acids Res. 2016

Computational modeling of RNA 3D structures and interactions

Dawson WK, Bujnicki JM

Curr Opin Struct Biol. 2016

SimRNA: a coarse-grained method for RNA folding simulations and 3D structure prediction

Boniecki MJ, Lach G, Dawson WK, Tomala K, Lukasz P, Soltysinski T, Rother KM, Bujnicki JM

Nucleic Acids Res. 2016

The architecture of the Schizosaccharomyces pombe CCR4-NOT complex

Ukleja M, Cuellar J, Siwaszek A, Kasprzak JM, Czarnocki-Cieciura M, Bujnicki JM, Dziembowski A, Valpuesta J

Nature Commun. 2016

Loss of conserved non-coding RNAs in genomes of bacterial endosymbionts

Matelska D, Kurkowska M, Purta E, Bujnicki JM, Dunin-Horkawicz S

Genome Biol Evol. 2016

Genome-wide survey of codons under diversifying selection in a highly recombining bacterial species, Helicobacter pylori

Yahara K, Furuta Y, Morimoto S, Kikutake C, Komukai S, Matelska D, Dunin-Horkawicz S, Bujnicki JM, Uchiyama I, Kobayashi I

DNA Res. 2016

SimRNAweb: a web server for RNA 3D structure modeling with optional restraints

Magnus MM, Boniecki MJ, Dawson WK, Bujnicki JM

Nucleic Acids Res.. 2016

Haloferax volcanii UbaA, catalytic engine for sampylation and sulfur transfer

Bochtler M., Piasecka A

FEBS J. 2016

mTOR kinase is needed for the development and stabilization of dendritic arbors in newly born olfactory bulb neurons

Skałecka A, Liszewska E, Bilinski R, Gkogkas C, Khoutorsky A, Malik AR, Sonenberg N, Jaworski J

Dev Neurobiol. 2016

Endocytic regulation of cytokine receptor signaling

Cendrowski J, Mamińska A, Miaczynska M

Cytokine Growth Factor Rev. 2016

Expression of microRNAs miR21, miR146a, and miR155 in tuberous sclerosis complex cortical tubers and their regulation in human astrocytes and SEGA-derived cell cultures

van Scheppingen J, Iyer AM, Prabowo AS, Mühlebner A, Anink JJ, Scholl T, Feucht M, Jansen FE, Spliet WG, Krsek P, Zamecnik J, Buccoliero AM, Giordano F, Genitori L, Kotulska K, Jozwiak S, Jaworski J, Liszewska E, van Vliet EA, Aronica E

Glia. 2016

LytM Fusion with SH3b-Like Domain Expands Its Activity to Physiological Conditions

Jagielska E, Chojnacka O, Sabala I

Microb Drug Resist. 2016

Protein Import by the Mitochondrial Presequence Translocase in the Absence of a Membrane Potential

Turakhiya U, von der Malsburg K, Gold VA, Guiard B, Chacinska A, van der Laan M, Ieva R

J Mol Biol. 2016

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

Di Cesare M, … Mossakowska M, … Slusarczyk P, … - 756 collaborators (NCD-RisC)

Lancet. 2016

Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants

Zhou B, … Mossakowska M, … Slusarczyk P, … - 513 collaborators (NCD-RisC)

Lancet. 2016

Socioeconomic determinants of prostate-specific antigen testing and estimation of the prevalence of undiagnosed prostate cancer in an elderly Polish population based on the PolSenior study

Prajsner A, Chudek J, Szybalska A, Piotrowicz K, Zejda J, Więcek A

Arch Med Sci. 2016

Prevalence of chronic pain in the elderly Polish population – results of the PolSenior study

Kozak-Szkopek E, Broczek K, Slusarczyk P, Wieczorowska-Tobis K, Klich-Raczka A, Szybalska A, Mossakowska M

Arch Med Sci. 2016

The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly

Wrobel L, Sokol AM, Chojnacka M, Chacinska A

Sci Rep. 2016

Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study

Puzianowska-Kuznicka M, Owczarz M, Wieczorowska-Tobis K, Nadrowski P, Chudek J, Slusarczyk P, Skalska A, Jonas M, Franek E, Mossakowska M

Immunity & Ageing. 2016

On the role of steric clashes in methylation control of restriction endonuclease activity

Mierzejewska K, Bochtler M, Czapinska H

Nucleic Acids Res. 2016

Isolation of Plant Photosystem II Complexes by Fractional Solubilization

Haniewicz P, Floris D, Farci D, Kirkpatrick J, Loi MC, Büchel C, Bochtler M, Piano D

Front Plant Sci. 2016

Chatty Mitochondria: Keeping Balance in Cellular Protein Homeostasis

Topf U, Wrobel L, Chacinska A

Trends Cell Biol. 2016

TLR-6 SNP P249S is associated with healthy aging in nonsmoking Eastern European Caucasians - A cohort study

Hamann L, Bustami J, Iakoubov L, Szwed M, Mossakowska M, Schumann RR, Puzianowska-Kuznicka M

Immun Ageing. 2016

Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity

Kevenaar JT, Bianchi S, van Spronsen M, Olieric N, Lipka J,Frias CP, Mikhaylova M, Harterink M, Keijzer N, Wulf PS, Hilbert M, Kapitein LC, de Graaff E, Ahkmanova A, Steinmetz MO, Hoogenraad CC

Curr Biol. 2016

APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain

Song J, Mu Y, Li C, Bergh A, Miaczynska M, Heldin CH, Landström M

Oncotarget. 2016

ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors

Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M

Sci Signal. 2016

DANIO-CODE: Toward an Encyclopedia of DNA Elements in Zebrafish

Tan H, Onichtchouk D, Winata C

Zebrafish. 2016

Structure and mechanism of nucleases regulated by SLX4

Nowotny M, Gaur V

Curr Opin Struct Biol. 2016

Physical activity, body composition and general health status of physically active students of the University of the Third Age (U3A)

Zajac-Gawlak I, Pospiech D, Kroemeke A, Mossakowska M, Gába A, Pelclová J, Pridalová M, Kłapcinska B

Archives of Gerontology and Geriatrics. 2016

Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites

Lipka J, Kapitein LC, Jaworski J, Hoogenraad CC

EMBO J. 2016

Dextran Nanoparticle Synthesis and Properties

Wasiak I, Kulikowska A, Janczewska M, Michalak M, Cymerman IA, Nagalski A, Kallinger P, Szymanski WW, Ciach T

PLoS One. 2016

Prevalence, awareness, and control of hypertension in elderly and very elderly in Poland: results of a cross-sectional representative survey

Zdrojewski T, Wizner B, Więcek A, Ślusarczyk P, Chudek J, Mossakowska M, Bandosz P, Bobak M, Kozakiewicz K, Broda G, Wyrzykowski B, Grodzicki T

J Hypertens. 2016

Impaired dynamin 2 function leads to increased AP-1 transcriptional activity through the JNK/c-Jun pathway

Szymanska E, Skowronek A, Miaczynska M

Cell Signal. 2016

Molecular anatomy of the thalamic complex and the underlying transcription factors

Nagalski A, Puelles L, Dabrowski M, Wegierski T, Kuznicki J, Wisniewska MB

Brain Struct Funct. 2016

2015

Phylogenomics and sequence-structure-function relationships in the GmrSD family of Type IV restriction enzymes.

Machnicka AM, Kaminska KH, Dunin-Horkawicz S, Bujnicki JM.

BMC Bioinformatics. 2015

Molecular mechanisms of induced pluripotency.

Kulcenty K, Wróblewska J, Mazurek S, Liszewska E, Jaworski J.

Contemp Oncol (Pozn). 2015

NeuroMorph: A Toolset for the Morphometric Analysis and Visualization of 3D Models Derived from Electron Microscopy Image Stacks.

Jorstad A, Nigro B, Cali C, Wawrzyniak M, Fua P, Knott G.

Neuroinformatics. 2015

Research reforms: Ukrainian science needs elixir of youth.

Vassetzky Y, Gout I, Kuznicki J.

Nature. 2015

RNAcentral: a comprehensive database of non-coding RNA sequences

The RNAcentral Consortium (Petrov AI et al within Bujnicki JM)

Nucleic Acids Res. 2015

Functional and evolutionary analyses of Helicobacter pylori HP0231 (DsbK) protein with strong oxidative and chaperone activity characterized by a highly diverged dimerization domain

Bocian-Ostrzycka KM, Łasica AM, Dunin-Horkawicz S, Grzeszczuk MJ, Drabik K, Dobosz AM, Godlewska R, Nowak E, Collet J-F, Jagusztyn-Krynicka EK

Frontiers in Microbiology. 2015

APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments

Kalaidzidis I, Miaczynska M, Brewińska-Olchowik M, Hupalowska A, Ferguson C, Parton RG, Kalaidzidis Y, Zerial M

J Cell Biol. 2015

Magnesium binding architectures in RNA crystal structures: validation binding preferences, classification, and motif detection

Zheng H, Shabalin I, Handing K, Bujnicki JM, Minor M

Nucleic Acids Res. 2015

NPDock – a web server for protein-nucleic acid docking

Tuszynska I, Magnus M, Jonak K, Dawson W, Bujnicki JM

Nucleic Acids Res. 2015

Biochemical Characterization and Validation of a Catalytic Site of a Highly Thermostable Ts2631 Endolysin from the Thermus scotoductus Phage vB_Tsc2631

Plotka M, Kaczorowska AK, Morzywolek A, Makowska J, Kozlowski LP, Thorisdottir A, Skírnisdottir S, Hjörleifsdottir S, Fridjonsson OH, Hreggvidsson GO, Kristjansson JK, Dabrowski S, Bujnicki JM, Kaczorowski T

PLoS One. 2015

Computational methods for prediction of RNA interactions with metal ions and small organic ligands

Philips A, Lach G, Bujnicki JM

Methods Enzymol. 2015

RNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures

Miao Z, Adamiak RW, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cheng C, Chojnowski G, Chou FC, Cordero P, Cruz JA, Ferré-D'amaré AR, Das R, Ding F, Dokholyan NV, Dunin-Horkawicz S, Kladwang W, Krokhotin A, Lach G, Magnus M, Major F, Mann TH, Masquida B, Matelska D, Meyer M, Peselis A, Popenda M, Purzycka KJ, Serganov A, Stasiewicz J, Szachniuk M, Tandon A, Tian S, Wang J, Xiao Y, Xu X, Zhang J, Zhao P, Zok T, Westhof E

RNA. 2015

A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing

Liu S, Mozaffari-Jovin S, Wollenhaupt J, Santos KF, Theuser M, Dunin-Horkawicz S, Fabrizio P, Bujnicki JM, Lührmann R, Wahl MC

eLife. 2015

Sequence-specific cleavage of dsRNA by Mini-III RNase

Glow D, Pianka D, Sulej A, Kozlowski L, Czarnecka J, Chojnowski G, Skowronek KJ, Bujnicki JM

Nucleic Acids Res. 2015

Characterization of the termini of the West Nile virus genome and their interactions with the small isoform of the 2' 5'-Oligoadenylate Synthetase family

Deo S, Patel TR, Chojnowski G, Koul A, Dzananovic E, McEleney K, Bujnicki JM, McKenna SA

J Struct Biol. 2015

Structure and intrinsic disorder of the proteins of the Trypanosoma brucei editosome

Czerwoniec A, Kasprzak JM, Bytner P, Dobrychlop M, Bujnicki JM

FEBS Lett. 2015

Brickworx builds recurrent RNA and DNA structural motifs into medium and low-resolution electron density maps

Chojnowski G, Walen T, Piatkowski P, Potrzebowski W, Bujnicki JM

Acta Crystallogr D Biol Crystallogr. 2015

An atlas of RNA base pairs involving modified nucleobases with optimal geometries and accurate energies

Chawla M, Oliva R, Bujnicki JM, Cavallo L

Nucleic Acids Res. 2015

A magnetic origin of cuprate superconductivity? A MaxEnt-mu SR view

Boekema C, Owens F, Love A, Li Z, Sakkaris P, Dawson WK

Int J Mod Phys B. 2015

The signature of the five-stranded vRRM fold defined by functional, structural and computational analysis of the hnRNP L protein

Blatter M, Dunin-Horkawicz S, Grishina I, Maris C, Thore S, Maier T, Bindereif A, Bujnicki JM, Allain FHT

J Mol Biol. 2015

Functional and evolutionary analyses of Helicobacter pylori HP0231 (DsbK) protein with strong oxidative and chaperone activity characterized by a highly diverged dimerization domain

Bocian-Ostrzycka KM, Łasica AM, Dunin-Horkawicz S, Grzeszczuk MJ, Drabik K, Dobosz AM, Godlewska R, Nowak E, Collet J-F, Jagusztyn-Krynicka EK

Frontiers in Microbiology. 2015

High resolution structure of an M23 peptidase with a substrate analogue

Grabowska M, Jagielska E, Czapinska H, Bochtler M, Sabala I

Sci Rep. 2015

Functional Analysis of Porphyromonas gingivalis W83 CRISPR-Cas Systems

Burmistrz M, Dudek B, Staniec D, Rodriguez Martinez JI, Bochtler M, Potempa J, Pyrc K

J Bacteriol. 2015

Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death

Keatinge M, Bui H, Menke A, Chen YC, Sokol AM, Bai Q, Ellett F, Da Costa M, Burke D, Gegg M, Trollope L, Payne T, McTighe A, Mortiboys H, de Jager S, Nuthall H, Kuo MS, Fleming A, Schapira AH, Renshaw SA, Highley JR, Chacinska A, Panula P, Burton EA, O'Neill MJ, Bandmann O

Hum Mol Genet. 2015

Non-catalytic N-terminal domain negatively influences the nucleotide exchange activity of translation elongation factor 1Bα

Trosiuk TV, Shalak VF, Szczepanowski RH , Negrutskii BS, El'skaya AV

FEBS J. 2015

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation

Zhao H, Ghirlando R, Alfonso C, Arisaka F, Attali I, Bain DL, Bakhtina MM, Becker DF, Bedwell GJ, Bekdemir A, Besong TM, Birck C, Brautigam CA, Brennerman W, Byron O, Bzowska A, Chaires JB, Chaton CT, Cölfen H, Connaghan KD, Crowley KA, Curth U, Daviter T, Dean WL, Díez AI, Ebel C, Eckert DM, Eisele LE, Eisenstein E, England P, Escalante C, Fagan JA, ... Szczepanowski RH,.. Schuck P

PLoS One. 2015

Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture

Esteves da Silva M, Adrian M, Schätzle P, Lipka J, Watanabe T, Cho S, Futai K, Wierenga CJ, Kapitein LC, Hoogenraad CC

Cell Rep. 2015

The oxidation status of Mic19 regulates MICOS assembly

Sakowska P, Jans DC, Mohanraj K, Riedel D, Jakobs S, Chacinska A

Mol Cell Biol. 2015

Tuberous sclerosis complex neuropathology requires glutamate-cysteine ligase

Malik AR, Liszewska E, Skalecka A, Urbanska M, Iyer AM, Swiech LJ, Perycz M, Parobczak K, Pietruszka P, Zarebska MM, Macias M, Kotulska K, Borkowska J, Grajkowska W, Tyburczy ME, Jozwiak S, Kwiatkowski DJ, Aronica E, Jaworski J

Acta Neuropathol Commun. 2015

Matricellular proteins of the Cyr61/CTGF/NOV (CCN) family and the nervous system

Malik AR, Liszewska E, Jaworski J

Front Cell Neurosci. 2015

Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3βMistargeted mitochondrial proteins activate a proteostatic response in the cytosol

Cymerman IA, Gozdz A, Urbanska M, Milek J, Dziembowska M, Jaworski J

PLoS One. 2015

APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription

Banach-Orlowska M, Szymanska E, Miaczynska M

FEBS Lett. 2015

Endocytic adaptor protein Tollip inhibits canonical Wnt signaling

Torun A, Szymańska E, Castanon I, Wolińska-Nizioł L, Bartosik A, Jastrzębski K, Miętkowska M, González-Gaitán M, Miaczynska M

PLoS One. 2015

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol

Wrobel L, Topf U, Bragoszewski P , Wiese S, Sztolsztener ME , Oeljeklaus S, Varabyova A, Lirski M, Chroscicki P, Mroczek S, Januszewicz E, Dziembowski A, Koblowska M, Warscheid B, Chacinska A

Nature. 2015

A Kinase Anchoring Protein 9 Is a Novel Myosin VI Binding Partner That Links Myosin VI with the PKA Pathway in Myogenic Cells

Karolczak J, Sobczak M, Skowronek K, Rędowicz MJ

Biomed Res Int.. 2015

Helicobacter pylori HP0377, a member of the Dsb family, is an untypical multifunctional CcmG that cooperates with dimeric thioldisulfide oxidase HP0231

Roszczenko P, Grzeszczuk M, Kobierecka P, Wywial E, Urbanowicz P, Wincek P, Nowak E, Jagusztyn-Krynicka EK

BMC Microbiol.. 2015

Plasma visfatin/nicotinamide phosphoribosyltransferase (visfatin/NAMPT) concentration in elderly subjects with metabolic syndrome

Kocełak P, Olszanecka-Glinianowicz M, Owczarek AJ, Krupa W, Obirek P, Bożentowicz-Wikarek M, Brzozowska A, Mossakowska M, Zdrojewski T, Skalska A, Więcek A, Chudek J

Pol Arch Med Wewn. 2015

Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment

Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K, Rominger A

Mol Psychiatry.. 2015

Retro-translocation of mitochondrial intermembrane space proteins

Bragoszewski P, Wasilewski M, Sakowska P, Gornicka A, Böttinger L, Qiu J, Wiedemann N, Chacinska A

Proc Natl Acad Sci U S A. 2015

Cox17 is an auxiliary factor involved in the control of the mitochondrial contact site and cristae organizing system

Chojnacka M, Gornicka A, Oeljeklaus S, Warscheid B, Chacinska A

J Biol Chem. 2015

Mitochondrial translocation of APE1 relies on the MIA pathway

Barchiesi A, Wasilewski M, Chacinska A, Tell G, Vascotto C

Nucleic Acids Res. 2015

Social and Economic Correlates of Malnutrition in Polish Elderly Population: The Results of PolSenior Study

Krzymińska-Siemaszko R, Mossakowska M, Skalska A, Klich-Rączka A, Tobis S, Szybalska A, Cylkowska-Nowak M, Olszanecka-Glinianowicz M, Chudek J, Wieczorowska-Tobis K.

J Nutr Health Aging. 2015

Inflammation but not obesity or insulin resistance is associated with increased plasma fibroblast growth factor 23 concentration in the elderly

Holecki M, Jerzy C, Owczarek A, Olszanecka-Glinianowicz M, Bożentowicz-Wikarek M, Duława J, Mossakowska M, Zdrojewski T, Skalska A, Więcek A

Clin Endocrinol (Oxf).. 2015

Association between vitamin D concentration and levels of sex hormones in an elderly Polish population with different genotypes of VDR polymorphisms (rs10735810, rs1544410, rs7975232, rs731236)

Laczmanski L, Lwow F, Mossakowska M, Puzianowska-Kuznicka M, Szwed M, Kolackov K, Krzyzanowska-Swiniarska B, Bar-Andziak E, Chudek J, Sloka N, Milewicz A

Gene.. 2015

Plasma fibroblast growth factor 23 concentration and iron status. Does the relationship exist in the elderly population?

Bożentowicz-Wikarek M, Kocełak P, Owczarek A, Olszanecka-Glinianowicz M, Mossakowska M, Skalska A, Więcek A, Chudek J

Clin Biochem. 2015

Plasma visfatin/nicotinamide phosphoribosyltransferase levels in hypertensive elderly - results from the PolSenior substudy

Kocelak P, Olszanecka-Glinianowicz M, Owczarek A, Bożentowicz-Wikarek M, Brzozowska A, Mossakowska M, Zdrojewski T, Grodzicki T, Więcek A, Chudek J

J Am Soc Hypertens. 2015

Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease

Gaur V, Wyatt HDM, Komorowska W, Szczepanowski RH, de Sanctis D, Gorecka KM, West SC, Nowotny M

Cell Reports. 2015

2-Thiouracil deprived of thiocarbonyl function preferentially base pairs with guanine rather than adenine in RNA and DNA duplexes

Sochacka E, Szczepanowski RH, Cypryk M, Sobczak M, Janicka M, Kraszewska K, Bartos P, Chwialkowska A, Nawrot B

Nucleic Acids Res. 2015

Dimerization and phosphatase activity of calcyclin-binding protein/Siah-1 interacting protein: the influence of oxidative stress

Topolska-Woś AM, Shell SM, Kilańczyk E, Szczepanowski RH, Chazin WJ, Filipek A

FASEB J.. 2015

Changing Faces of Transcriptional Regulation Reflected by Zic3

Winata CL, Kondrychyn I, Korzh V

Current Genomics. 2015

SOCE in neurons: Signaling or just refilling?

Majewski L, Kuznicki J

BBA-Mol Cell Res. 2015

Paraoxonase 1 activity and level of antibodies directed against oxidized low density lipoproteins in a group of an elderly population in Poland - PolSenior study.

Bednarska-Makaruk M, Rodo M, Szirkowiec W, Mossakowska M, Puzianowska-Kuźnicka M, Skalska A, Zdrojewski T, Ryglewicz D, Wehr H

Arch Gerontol Geriatr.. 2015

Socioeconomic profile of elderly Polish men treated for benign prostate hyperplasia: Results of the population-based PolSenior study

Prajsner A, Chudek J, Szybalska A, Piotrowicz K, Zejda J, Więcek A, PolSenior Study Group

European Geriatric Medicine. 2015

A Common Copy Number Variation Polymorphism in the CNTNAP2 Gene: Sexual Dimorphism in Association with Healthy Aging and Disease

Iakoubov L, Mossakowska M, Szwed M, Puzianowska-Kuznicka M

Gerontology. 2015

Missense variant in CCDC22 causes X-linked recessive intellectual disability with features of Ritscher-Schinzel/3C syndrome

Kolanczyk M, Krawitz P, Hecht J, Hupalowska A, Miaczynska M, Marschner K, Schlack C, Emerich D, Kobus K, Kornak U, Robinson PN, Plecko B, Grangl G, Uhrig S, Mundlos S, Horn D

Eur J Hum Genet. 2015

Age-related changes of leptin and leptin receptor variants in healthy elderly and long-lived adults

Roszkowska-Gancarz M, Jonas M, Owczarz M , Kurylowicz A, Polosak J, Franek E, Slusarczyk P, Mossakowska M, Puzianowska-Kuznicka M

Geriatr Gerontol Int. 2015

High resolution structure of an M23 peptidase with a substrate analogue

Grabowska M, Jagielska E, Czapinska H, Bochtler M, Sabala I

Sci Rep. 2015

2014

Crystal structure of RNase H3-substrate complex reveals parallel evolution of RNA/DNA hybrid recognition.

Figiel M, Nowotny M.

Nucleic Acids Res.. 2014

Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression.

Mathys H, Basquin J, Ozgur S, Czarnocki-Cieciura M, Bonneau F, Aartse A, Dziembowski A, Nowotny M, Conti E, Filipowicz W.

Mol Cell.. 2014

Distribution and frequencies of post-transcriptional modifications in tRNAs.

Machnicka M, Olchowik A, Grosjean H, Bujnicki JM.

RNA Biol.. 2014

RNA methyltransferases involved in 5' cap biosynthesis.

Byszewska M, Smietanski M, Purta E, Bujnicki JM.

RNA Biol.. 2014

Carboxy terminus of GATA4 transcription factor is required for its cardiogenic activity and interaction with CDK4

Gallagher JM, Yamak A, Kirilenko P, Black S, Bochtler M, Lefebvre C, Nemer M, Latinkić BV

Mech Dev. 2014

Ocena sprawności funkcjonalnej warszawskich stulatków w zakresie podstawowych czynności życia codziennego – wyniki wstępne

Skubiszewska A, Wodzyńska K, Szybalska A, Ślusarczyk P, Broczek K, Puzianowska-Kuźnicka M, Olędzka G, Mossakowska M

Gerontologia Polska. 2014

Plasma visfatin/nicotinamide phosphoribosyltransferase (visfatin/NAMPT) concentration is not related to kidney function in elderly subjects

Kocelak P, Olszanecka-Glinianowicz M, Owczarek A, Bozentowicz-Wikarek M, Brzozowska A, Mossakowska M, Skalska A, Wiecek A, Chudek J

Clin Chem Lab Med.. 2014

Cellular control of cortical actin nucleation

Bovellan M, Romeo Y, Biro M, Boden A, Chugh P, Yonis A, Vaghela M, Fritzsche M, Moulding D, Thorogate R, Jégou A, Thrasher AJ, Romet-Lemonne G, Roux PP, Paluch EK, Charras G

Curr Biol. 2014

Mgr2 functions as lateral gatekeeper for preprotein sorting in the mitochondrial inner membrane

Ieva R, Schrempp SG, Opaliński L Wollweber F, Höß P, Heißwolf AK, Gebert M, Zhang Y, Guiard B, Rospert S, Becker T, Chacinska A, Pfanner N, van der Laan M

Mol Cell.. 2014

Identification of tetrahydrocarbazoles as novel multifactorial drug candidates for treatment of Alzheimer's disease

Honarnejad K, Daschner A, Gehring AP, Szybinska A, Giese A, Kuznicki J, Bracher F, Herms J

Transl Psychiatry.. 2014

Designability landscape reveals sequence features that define axial helix rotation in four-helical homo-oligomeric antiparallel coiled-coil structures

Szczepaniak K, Lach G, Bujnicki JM, Dunin-Horkawicz S

J Struct Biol.. 2014

Functional and bioinformatics analysis of two Campylobacter jejuni homologs of the thiol-disulfide oxidoreductase, DsbA

Grabowska AD, Wywiał E, Dunin-Horkawicz S , Lasica AM, Wösten MM, Nagy-Staroń A, Godlewska R, Bocian-Ostrzycka K, Pieńkowska K, Laniewski P, Bujnicki JM, van Putten JP, Jagusztyn-Krynicka EK

PLoS One.. 2014

ClaRNA: a classifier of contacts in RNA 3D structures based on a comparative analysis of various classification schemes

Walen T, Chojnowski G, Gierski P,Bujnicki JM,

Nucleic Acids Res.. 2014

Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2

Ramos-Molina B, Lambertos A, Lopez-Contreras AJ, Kasprzak JM, Czerwoniec A, Bujnicki JM, Cremades A, Penafiel R

FEBS Open Bio.. 2014

Female-specific gene expression in dioecious liverwort Pellia endiviifolia is developmentally regulated and connected to archegonia production

Sierocka I, Kozlowski LP, Bujnicki JM, Jarmolowski A, Szweykowska-Kulinska Z

BMC Plant Biol.. 2014

Computational modeling of RNA 3D structures, with the aid of experimental restraints

Magnus M, Matelska D, Lach G, Chojnowski G, Boniecki MJ, Purta E, Dawson W, Dunin-Horkawicz S, Bujnicki JM

RNA Biol.. 2014

Automated modeling of RNA 3D structure

Rother K, Rother M, Skiba P, Bujnicki JM

Methods Mol Biol. 2014

Crystal structure of the catalytic core of Rad2: insights into the mechanism of substrate binding

Miętus M, Nowak E, Jaciuk M, Kustosz P, Studnicka J, Nowotny M

Nucleic Acids Res. 2014

A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria

Gornicka A, Bragoszewski P, Chroscicki P, Wenz LS, Schulz C, Rehling P, Chacinska A

Mol Biol Cell. 2014

Recent advances in primary ciliary dyskinesia genetics

Kurkowiak M, Ziętkiewicz E, Witt M

J Med Genet. 2014

Presequence recognition by the tom40 channel contributes to precursor translocation into the mitochondrial matrix

Melin J, Schulz C, Wrobel L, Bernhard O, Chacinska A, Jahn O, Schmidt B, Rehling P

Mol Cell Biol. 2014

Mitochondrial protein translocases for survival and wellbeing

Sokol AM, Sztolsztener ME, Wasilewski M, Heinz E, Chacinska A

FEBS Lett. 2014

Reduced functionality in everyday activities of patients with self-reported heart failure hospitalization - Population-based study results

Skalska A, Wizner B, Więcek A, Zdrojewski T, Chudek J, Klich-Rączka A, Piotrowicz K, Błędowski P, Mossakowska M, Michel JP, Grodzicki T

Int J Cardiol. 2014

Relationship between circulating visfatin/NAMPT, nutritional status and insulin resistance in an elderly population - results from the PolSenior substudy

Olszanecka-Glinianowicz M, Owczarek A, Bożentowicz-Wikarek M, Brzozowska A, Mossakowska M, Zdrojewski T, Grodzicki T, Więcek A, Chudek J

Metabolism. 2014

Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans

Sabala I, Jagielska E, Bardelang PT, Czapinska H, Dahms SO, Sharpe JA, James R, Than ME, Thomas NR, Bochtler M

FEBS J. 2014

Structural basis of the methylation specificity of R.DpnI

Mierzejewska K, Siwek W, Czapinska H, Kaus-Drobek M, Radlinska M, Skowronek K, Bujnicki JM, Dadlez M, Bochtler M

Nucleic Acids Res.. 2014

Insights into DNA hydroxymethylation in the honeybee from in-depth analyses of TET dioxygenase

Wojciechowski M, Rafalski D, Kucharski R, Misztal K, Maleszka J, Bochtler M, Maleszka R

Open Biol. 2014

Cognitive flexibility and long-term depression (LTD) are impaired following β-catenin stabilization in vivo

Mills F, Bartlett TE, Dissing-Olesen L, Wisniewska MB, Kuznicki J, Macvicar BA, Wang YT, Bamji SX

Proc Natl Acad Sci U S A.. 2014

The assessment of cognitive impairment suspected of dementia in Polish elderly people: results of the population-based PolSenior Study

Klich-Rączka A, Piotrowicz K, Mossakowska M, Skalska A, Wizner B, Broczek K, Wieczorowska-Tobis K, Grodzicki T

Exp Gerontol. 2014

Interrelation between genotypes of the vitamin D receptor gene and serum sex hormone concentrations in the Polish elderly population: the PolSenior study

Laczmanski L, Milewicz A, Puzianowska-Kuznicka M, Lwow F, Kolackov K, Mieszczanowicz U, Pawlak M, Krzyzanowska-Swiniarska B, Bar-Andziak E, Chudek J, Mossakowska M

Exp Gerontol. 2014

Secondary prevention of stroke in elderly people in Poland-Results of PolSenior study

Labuz-Roszak B, Skrzypek M, Pierzchała K, Machowska-Majchrzak A, Mossakowska M, Chudek J, Mańka-Gaca I, Bartman W, Więcek A

Neurol Neurochir Pol. 2014

Fibroblast growth factor 23 (FGF23) and early chronic kidney disease in the elderly

Chudek J, Kocełak P, Owczarek A, Bozentowicz-Wikarek M, Mossakowska M, Olszanecka-Glinianowicz M, Wiecek A

Nephrol Dial Transplant. 2014

Functional polymorphisms of the leptin and leptin receptor genes are associated with longevity and with the risk of myocardial infarction and of type 2 diabetes mellitus

Roszkowska-Gancarz M, Kurylowicz A, Polosak J, Mossakowska M, Franek E, Puzianowska-Kuźnicka M

Endokrynol Pol. 2014

The RNase H-like superfamily: new members, comparative structural analysis and evolutionary classification

Majorek KA, Dunin-Horkawicz S, Steczkiewicz K, Muszewska A, Nowotny M, Ginalski K, Bujnicki JM

Nucleic Acids Res.. 2014

Uniform nomenclature for the mitochondrial contact site and cristae organizing system

Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J

J Cell Biol.. 2014

Potassium channel in the mitochondria of human keratinocytes

Toczyłowska-Mamińska R, Olszewska A, Laskowski M, Bednarczyk P, Skowronek K, Szewczyk A

J Invest Dermatol. 2014

Labeling of platelet-derived growth factor by reversible biotinylation to visualize its endocytosis by microscopy

Sadowski Ł, Jastrzębski K, Purta E, Hellberg C, Miaczynska M

Methods Enzymol.. 2014

Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target

Tomecki R, Drazkowska K, Kucinski I, Stodus K, Szczesny RJ, Gruchota J, Owczarek EP, Kalisiak K, Dziembowski A

Nucleic Acids Res.. 2014

New simple efficient algorithms computing powers and runs in strings

Crochemore M, Iliopoulos CS, Kubica M, Radoszewski J, Rytter W, Stencel K, Walen T

Discrete Applied Mathematics. 2014

Crystal structure of the 5hmC specific endonuclease PvuRts1I

Kazrani AA, Kowalska M, Czapinska H, Bochtler M

Nucleic Acids Res.. 2014

CFTR Mutations Spectrum and the Efficiency of Molecular Diagnostics in Polish Cystic Fibrosis Patients

Ziętkiewicz E, Rutkiewicz E, Pogorzelski A, Klimek B, Voelkel K, Witt M

PLoS One. 2014

Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry

Nowak E, Miller JT, Bona MK, Studnicka J, Szczepanowski RH, Jurkowski J, Le Grice SFJ, Nowotny M

Nature Structural & Molecular Biology. 2014

Patterns of structural dynamics in RACK1 protein retained throughout evolution: A hydrogen-deuterium exchange study of three orthologs

Tarnowski K, Fituch K, Szczepanowski RH, Dadlez M, Kaus-Drobek M

Protein Sci. 2014

The GRIP1/14-3-3 Pathway Coordinates Cargo Trafficking and Dendrite Development

Geiger JC, Lipka J, Segura I, Hoyer S, Schlager MA, Wulf PS, Weinges S, Demmers J, Hoogenraad CC, Acker-Palmer A

Dev Cell. 2014

Cognitive Performance and Functional Status Are the Major Factors Predicting Survival of Centenarians in Poland

Mossakowska M , Broczek K, Wieczorowska-Tobis K, Klich-Raczka A, Jonas M, Pawlik-Pachucka E, Safranow K, Kuznicki J , Puzianowska-Kuznicka M

J Gerontol A Biol Sci Med Sci. 2014

Ciliary genes are down-regulated in bronchial tissue of primary ciliary dyskinesia patients

Geremek M, Ziętkiewicz E, Bruinenberg M, Franke L, Pogorzelski A, Wijmenga C, Witt M

PLoS One. 2014

Structural analysis of human 2′-O-ribose methyltransferases involved in mRNA cap structure formation

Smietanski M, Werner M, Purta E, Kaminska KH, Stepinski J, Darzynkiewicz E, Nowotny M, Bujnicki JM

Nat Commun. 2014

RNA Bricks - a database of RNA 3D motifs and their interactions

Chojnowski G, Walen T, Bujnicki JM

Nucleic Acids Res.. 2014

Solution conformation of Adenovirus Virus Associated RNA-I and its interaction with PKR

Dzananovic E, Patel TR, Chojnowski G, Boniecki MJ, Deo S, McEleney K, Harding SE, Bujnicki JM, McKenna SA

J Struct Biol. 2014

Novel Highly Thermostable Endolysin from Thermus scotoductus MAT2119 Bacteriophage Ph2119 with Amino Acid Sequence Similarity to Eukaryotic Peptidoglycan Recognition Proteins

Plotka M, Kaczorowska AK, Stefanska A, Morzywolek A, Fridjonsson OH, Dunin-Horkawicz S, Kozlowski L, Hreggvidsson GO, Kristjansson JK, Dabrowski S, Bujnicki JM, Kaczorowski T

Appl Environ Microbiol. 2014

Computational modeling of protein-RNA complex structures

Tuszynska I, Matelska D, Magnus M, Chojnowski G, Kasprzak JM, Kozlowski LP, Dunin-Horkawicz S, Bujnicki JM

Methods. 2014

NMR structural studies of the first catalytic half-domain of ubiquitin activating enzyme

Jaremko M, Jaremko L, Nowakowski M, Wojciechowski M, Szczepanowski RH, Panecka R, Zhukov I, Bochtler M, Ejchart A

J Struct Biol. 2014

CD44 regulates dendrite morphogenesis through Src tyrosine kinase-dependent positioning of the Golgi

Skupien A, Konopka A, Trzaskoma P, Labus J, Gorlewicz A, Swiech L, Babraj M, Dolezyczek H, Figiel I, Ponimaskin E, Wlodarczyk J, Jaworski J, Wilczynski GM, Dzwonek J

J Cell Sci. 2014

2013

Dietary intakes of iron and zinc assessed in a selected group of the elderly: are they adequate

Madej D, Borowska K, Bylinowska J, Szybalska A, Pietruszka B

Rocz Panstw Zakl Hig. 2013

Perceptible shape of memories

Jaworski J

Biologia w szkole. 2013

Why do we need induced pluripotent stem cells in neurobiology?

Liszewska E, Jaworski J

Postepy Biochem. 2013

Mikroskopowe metody rejestracji wewnątrzkomórkowych odpowiedzi wapniowych

Wegierski T

Kosmos. 2013

The role and regulation of blebs in cell migration

Paluch EK, Raz E

Curr Opin Cell Biol. 2013

Rational design of helical nanotubes from self-assembly of coiled-coil lock washers

Xu C, Liu R, Mehta AK, Guerrero-Ferreira RC, Wright ER, Dunin-Horkawicz S, Morris K, Serpell LC, Zuo X, Wall JS, Conticello VP

J Am Chem Soc.. 2013

Crystal structure of RuvC resolvase in complex with Holliday junction substrate

Górecka KM, Komorowska W, Nowotny M

Nucleic Acids Res. 2013

Cell cortex composition and homeostasis resolved by integrating proteomics and quantitative imaging

Biro M, Romeo Y, Kroschwald S, Bovellan M, Boden A, Tcherkezian J, Roux PP, Charras G, Paluch EK

Cytoskeleton (Hoboken). 2013

Isolation of monomeric photosystem II that retains the subunit PsbS

Haniewicz P, De Sanctis D, Büchel C, Schröder WP, Loi MC, Kieselbach T, Bochtler M, Piano D

Photosynth Res. 2013

LigandRNA: computational predictor of RNA-ligand interactions

Philips A, Milanowska K, Lach G, Bujnicki JM

RNA. 2013

Caveolin-1 - a novel interacting partner of organic cation/carnitine transporter (octn2): effect of protein kinase C on this interaction in rat astrocytes.

Czeredys M, Samluk L, Michalec K, Tułodziecka K, Skowronek K, Nałęcz KA

PLoS One. 2013

Telomere Length in Elderly Caucasians Weakly Correlates with Blood Cell Counts

Gutmajster E, Witecka J, Wyskida M, Koscinska-Marczewska J, Szwed M, Owczarz M, Mossakowska M, Milewicz A, Puzianowska-Kuznicka M, Zejda J, Wiecek A, Chudek J, Sieron A.L

The Scientific World Journal. 2013

Development and Implementation of a High-Throughput Compound Screening Assay for Targeting Disrupted ER Calcium Homeostasis in Alzheimer's Disease

Honarnejad K, Daschner A, Giese A, Zall A, Schmidt B, Szybinska A, Kuznicki J, Herms J

PLoS One. 2013

Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington’s disease

Czeredys M, Gruszczynska-Biegala J, Schacht T, Methner A, Kuznicki J

Front. Mol. Neurosci. 2013

Mutations in cytoplasmic dynein and its regulators cause malformations of cortical development and neurodegenerative diseases

Lipka J, Kuijpers M,Jaworski J, Hoogenraad CC

Biochem Soc Trans. 2013

FRET-Based Calcium Imaging: A Tool for High-Throughput/Content Phenotypic Drug Screening in Alzheimer Disease

Honarnejad K, Kirsch AK, Daschner A, Szybinska A, Kuznicki J, Herms J

J Biomol Screen. 2013

The fragile x mental retardation protein regulates matrix metalloproteinase 9 mRNA at synapses

Janusz A, Milek J, Perycz M, Pacini L, Bagni C, Kaczmarek L, Dziembowska M

J Neurosci. 2013

A Common Copy Number Variation (CNV) Polymorphism in the CNTNAP4 Gene: Association with Aging in Females

Iakoubov L, Mossakowska M, Szwed M, Duan Z, Sesti F, Puzianowska-Kuznicka M

PLoS One. 2013

Effects of membrane trafficking on signaling by receptor tyrosine kinases

Miaczynska M

Cold Spring Harb Perspect Biol.. 2013

Native STIM2 and ORAI1 proteins form a calcium-sensitive and thapsigargin-insensitive complex in cortical neurons

Gruszczynska-Biegala J, Kuznicki J

J Neurochem. 2013

Adhesion, but not a specific cadherin code, is indispensable for ES cell and induced pluripotency

Bedzhov I, Alotaibi H, Basilicata MF, Ahlborn K,Liszewska E, Brabletz T, Stemmler MP

Stem Cell Res. 2013

S6:S18 ribosomal protein complex interacts with a structural motif present in its own mRNA

Matelska D, Purta E, Panek S, Boniecki MJ, Bujnicki JM, Dunin-Horkawicz S

RNA. 2013

Cross-linked glucose oxidase clusters for biofuel cell anode catalysts

Dudzik J, Chang WC, Kannan AM, Filipek S, Viswanathan S, Li P, Renugopalakrishnan V, Audette GF

Biofabrication. 2013

Monitoring actin cortex thickness in live cells

Clark AG, Dierkes K, Paluch EK

Biophys J. 2013

Enhancing the production of galacto-oligosaccharides by mutagenesis of Sulfolobus solfataricus β-galactosidase

Wu Y, Yuan S, Chen S, Wu D, Chen J, Wu J

Food Chem. 2013

A linear time algorithm for consecutive permutation pattern matching

Kubica M, Kulczyńskia T, Radoszewskia J, Rytter W,Walen T

Information Processing Letters. 2013

Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain

Bednarczyk P, Wieckowski MR, Broszkiewicz M, Skowronek K, Siemen D, Szewczyk A

PLoS One. 2013

Low-temperature molecular dynamics simulations of horse heart cytochrome c and comparison with inelastic neutron scattering data

Pulawski W, Filipek S, Zwolinska A, Debinski A, Krzysko K, Garduño-Juárez R, Viswanathan S, Renugopalakrishnan V

Eur Biophys J. 2013

RNase H2 roles in genome integrity revealed by unlinking its activities

Chon H, Sparks JL, Rychlik M, Nowotny M, Burgers PM, Crouch RJ, Cerritelli SM

Nucleic Acids Res. 2013

A note on efficient computation of all Abelian periods in a string

Crochemore M, Iliopoulos C.S, Kociumaka T, Kubica M, Pachocki J, Radoszewski J, Rytter W,Tyczyński W, Waleń T

Information Processing Letters. 2013

Towards Improved Quality of GPCR Models by Usage of Multiple Templates and Profile-Profile Comparison

Latek D, Pasznik P, Carlomagno T, Filipek S

PLoS One. 2013

Alzheimer's disease modeling: ups, downs, and perspectives for human induced pluripotent stem cells

Wojda U, Kuznicki J

J Alzheimers Dis. 2013

Cell adhesion mechanics of zebrafish gastrulation

Maître JL, Berthoumieux H, Gabriel Krens SF, Salbreux G, Jülicher F, Paluch E, Heisenberg CP

M S-MEDECINE SCIENCES. 2013

Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation

Qiu J, Wenz LS, Zerbes RM, Oeljeklaus S, Bohnert M, Stroud DA, Wirth C, Ellenrieder L, Thornton N, Kutik S, Wiese S, Schulze-Specking A, Zufall N, Chacinska A, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N, Wiedemann N, Becker T

Cell. 2013

Mia40 and MINOS act in parallel with Ccs1 in the biogenesis of mitochondrial Sod1

Varabyova A, Topf U, Kwiatkowska P, Wrobel L, Kaus-Drobek M, Chacinska A

FEBS J. 2013

QA-RecombineIt: a server for quality assessment and recombination of protein models

Pawlowski M, Bogdanowicz A, Bujnicki JM

Nucleic Acids Res. 2013

RNAlyzer--novel approach for quality analysis of RNA structural models

Lukasiak P, Antczak M, Ratajczak T, Bujnicki JM, Szachniuk M, Adamiak RW, Popenda M, Blazewicz J

Nucleic Acids Res. 2013

Bioinformatics and computational biology in Poland

Bujnicki JM, Tiuryn J

PLoS Comput Biol. 2013

CompaRNA: a server for continuous benchmarking of automated methods for RNA secondary structure prediction

Puton T, Kozlowski LP, Rother KM, Bujnicki JM

Nucleic Acids Res.. 2013

Plasma level of N-terminal pro brain natriuretic peptide (NT-proBNP) in elderly population in Poland - the PolSenior Study

Nadrowski P, Chudek J, Grodzicki T, Mossakowska M, Skrzypek M, Wiecek A, Zdrojewski T, Kozakiewicz K

Exp Gerontol.. 2013

The prion protein M129V polymorphism: Longevity and cognitive impairment among Polish centenarians

Golanska E, Sieruta M, Corder E, Gresner SM, Pfeffer A, Chodakowska-Zebrowska M, Sobow TM, Klich I, Mossakowska M, Szybinska A, Barcikowska M, Liberski PP

Prion. 2013

Spatiotemporal Characterization of mTOR Kinase Activity Following Kainic Acid Induced Status Epilepticus and Analysis of Rat Brain Response to Chronic Rapamycin Treatment

Macias M, Blazejczyk M, Kazmierska P, Caban B, Skalecka A, Tarkowski B, Rodo A, Konopacki J, Jaworski J

PLoS One. 2013

Myosin-V Opposes Microtubule-Based Cargo Transport and Drives Directional Motility on Cortical Actin

Kapitein LC, van Bergeijk P, Lipka J, Keijzer N, Wulf PS, Katrukha EA, Akhmanova A, Hoogenraad CC

Curr Biol. 2013

Dynamin Inhibitors Impair Endocytosis and Mitogenic Signaling of PDGF

Sadowski L, Jastrzębski K, Kalaidzidis Y, Heldin CH, Hellberg C, Miaczynska M

Traffic. 2013

The ubiquitin-proteasome system regulates mitochondrial intermembrane space proteins

Bragoszewski P, Gornicka A, Sztolsztener ME, Chacinska A

Mol Cell Biol. 2013

Brain-derived neurotrophic factor induces matrix metalloproteinase-9 expression in neurons via serum response factor/c-Fos pathway

Kuzniewska B, Rejmak E, Malik AR, Jaworski J, Kaczmarek L, Kalita K

Mol Cell Biol. 2013

TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites

van Spronsen M, Mikhaylova M, Lipka J, Schlager MA, van den Heuvel DJ, Kuijpers M, Wulf PS, Keijzer N, Demmers J, Kapitein LC, Jaarsma D, Gerritsen HC, Akhmanova A, Hoogenraad CC

Neuron. 2013

Analysis of calcium homeostasis in fresh lymphocytes from patients with sporadic Alzheimer's disease or mild cognitive impairment

Jaworska A, Dzbek J, Styczynska M, Kuznicki J

Biochim Biophys Acta. 2013

Assessment of adiponectin and its isoforms in Polish centenarians

Bik W, Baranowska-Bik A, Wolinska-Witort E, Kalisz M, Broczek K, Mossakowska M, Baranowska B

Exp Gerontol. 2013

APBB2 genetic polymorphisms are associated with severe cognitive impairment in centenarians

Golanska E, Sieruta M, Gresner SM, Pfeffer A, Chodakowska-Zebrowska M, Sobow TM, Klich I, Mossakowska M, Szybinska A, Barcikowska M, Liberski PP

Exp Gerontol. 2013

Physiological Role of β-Catenin/TCF Signaling in Neurons of the Adult Brain

Wisniewska MB

Neurochem Res. 2013

Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid

Nowak E, Potrzebowski W, Konarev PV, Rausch JW, Bona MK, Svergun DI, Bujnicki JM, Le Grice SF, Nowotny M

Nucleic Acids Res. 2013

CYR61, a matricellular protein, is needed for dendritic arborization of hippocampal neurons

Malik AR, Urbanska M, Gozdz A, Swiech LJ, Nagalski A, Perycz M, Blazejczyk M, Jaworski J

J Biol Chem. 2013

Mitochondrial protein import: Mia40 facilitates Tim22 translocation into the inner membrane of mitochondria

Wrobel L, Trojanowska A, Sztolsztener ME, Chacinska A

Mol Biol Cell. 2013

Mitochondrial protein homeostasis

Varabyova A, Stojanovski D, Chacinska A

IUBMB Life. 2013

Hsp90 and its co-chaperone, Sgt1, as autoantigens in dilated cardiomyopathy

Kapustian LL, Vigontina OA, Rozhko OT, Ryabenko DV, Michowski W, Lesniak W, Filipek A, Kroupskaya IV, Sidorik LL

Heart Vessels. 2013

Total and high molecular weight adiponectin and level-modifying polymorphisms of ADIPOQ in centenarians

Roszkowska-Gancarz M, Bartoszewicz Z, Polosak J, Kurylowicz A, Jonas M, Mossakowska M, Franek E, Puzianowska-Kuźnicka M

Endokrynologia Polska. 2013

Beyond control of protein translation: What we have learned about the non-canonical regulation and function of mammalian target of rapamycin (mTOR)

Malik AR, Urbanska M, Macias M, Skalecka A, Jaworski J

Biochim Biophys Acta. 2013

Downregulation of extracellular signal-regulated kinase 1/2 activity by calmodulin KII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer's disease patients

Esteras N, Alquézar C, Bermejo-Pareja F, Bialopiotrowicz E, Wojda U, Martín-Requero A

Neurobiol Aging. 2013

RNApathwaysDB – a database of RNA maturation and decay pathways

Milanowska K, Mikolajczak K, Lukasik A, Skorupski M, Balcer Z, Machnicka MA, Nowacka M, Rother KM, Bujnicki JM

Nucleic Acids Res. 2013

MODOMICS: a database of RNA modification pathways: 2013 update

Machnicka MA, Milanowska K, Osman Oglou O, Purta E, Kurkowska M, Olchowik A, Januszewski W, Kalinowski S, Dunin-Horkawicz S, Rother KM, Helm M, Bujnicki JM, Grosjean H

Nucleic Acids Res. 2013

Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain

Nagalski A, Irimia M, Szewczyk L, Ferran JL, Misztal K, Kuznicki J, Wisniewska MB

Brain Struct Funct. 2013

CpG Underrepresentation and the Bacterial CpG Specific DNA Methyltransferase M.MpeI

Wojciechowski M, Czapinska H, Bochtler M

Proc Natl Acad Sci U S A.. 2013

Disulfide bond formation: sulfhydryl oxidase ALR controls mitochondrial biogenesis of human MIA40

Sztolsztener ME, Brewinska A, Guiard B, Chacinska A

Traffic. 2013

Multifunctional protein APPL2 contributes to survival of human glioma cells

Pyrzynska B, Banach-Orlowska M, Teperek-Tkacz M, Miekus K, Drabik G, Majka M, Miaczynska M

Mol Oncol.. 2013

BCL11B, FLT3, NOTCH1 and FBXW7 mutation status in T-cell Acute Lymphoblastic Leukemia patients

Kraszewska MD, Dawidowska M, Kosmalska M, Sędek Ł, Grzeszczak W, Kowalczyk JR, Szczepański T, Witt M

Blood Cells, Molecules and Diseases. 2013

Biologia syntetyczna: jak powstawało życie na Ziemi?

Żylicz M.

Nauka. 2013

2012

The Prevalence of Dementia in Warsaw Centenarians: a Population – Based Study

Pfeffer A, Chodakowska M, Czyżewski K, Gabryelewicz T, Łuczywek Ł, Mossakowska M, Broczek K, Barcikowska M

Postępy Nauk Medycznych. 2012

Structure prediction of alternatively spliced proteins In „Alternative pre-mRNA Splicing: Theory and Protocols: The Complete Guide for Biomedical Scientists”

Kozlowski L, Orlowski J, Bujnicki JM

. 2012

Template-based and template-free modeling of RNA 3D structure: inspirations from protein structure modeling In "RNA Structure Prediction and Modelling"

Rother K, Rother M, Boniecki M, Puton T, Tomala K, Lukasz P, Bujnicki JM

. 2012

Ubiquitous amyloids

Pulawski W, Ghoshdastider U, Andrisano V, Filipek S

Appl Biochem Biotechnol. 2012

MetaDisorder: A meta-server for the prediction of intrinsic disorder in proteins

Kozlowski LP, Bujnicki JM

BMC Bioinformatics. 2012

Molecular evolution of dihydrouridine synthases

Kasprzak JM, Czerwoniec A, Bujnicki JM

BMC Bioinformatics. 2012

Intrinsic disorder in the human spliceosomal proteome

Korneta I, Bujnicki JM

PLoS Comput Biol. 2012

Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage

Kusio-Kobialka M, Wolanin K, Podszywalow-Bartnicka P, Sikora E, Skowronek K, McKenna SL, Ghizzoni M, Dekker FJ, Piwocka K

Apoptosis. 2012

A novel insight into the oxidoreductase activity of Helicobacter pylori HP0231 protein

Roszczenko P, Radomska KA, Wywial E, Collet JF, Jagusztyn-Krynicka EK

PLoS One. 2012

A novel homozygous p.Arg527Leu LMNA mutation in two unrelated egyptian families causes overlapping mandibuloacral dysplasia and progeria syndrome

Al-Haggar M, Madej-Pilarczyk A, Kozlowski L, Bujnicki JM, Yahia S, Abdel-Hadi D, Shams A, Ahmad N, Hamed S, Puzianowska-Kuznicka M

Eur J Hum Genet. 2012

Amyloid β-Peptide 25-35 Self-Assembly and Its Inhibition: A Model Undecapeptide System to Gain Atomistic and Secondary Structure Details of the Alzheimer's Disease Process and Treatment

Naldi M, Fiori J, Pistolozzi M, Drake AF, Bertucci C, Wu R, Mlynarczyk K, Filipek S, De Simone A, Andrisano V

ACS Chem Neurosci. 2012

The Role of Water in Activation Mechanism of Human N-Formyl Peptide Receptor 1 (FPR1) Based on Molecular Dynamics Simulations

Yuan S, Ghoshdastider U, Trzaskowski B, Latek D, Debinski A, Pulawski W, Wu R, Gerke V, Filipek S

PLoS One. 2012

MetaLocGramN: A meta-predictor of protein subcellular localization for Gram-negative bacteria

Magnus M, Pawlowski M, Bujnicki JM

Biochim Biophys Acta. 2012

Vitamin D receptor gene polymorphism and cardiovascular risk variables in elderly Polish subjects

Laczmanski L, Milewicz A, Lwow F, Puzianowska-Kuznicka M, Pawlak M, Kolackov K, Jedrzejuk D, Krzyzanowska-Swiniarska B, Bar-Andziak E, Chudek J, Mossakowska M

Gynecol Endocrinol. 2012

The prevalence of falls and their relation to visual and hearing impairments among a nation-wide cohort of older Poles

Skalska A, Wizner B, Piotrowicz K, Klich-Rączka A, Klimek E, Mossakowska M, Rowiński R, Kozak-Szkopek E, Jóźwiak A, Gąsowski J, Grodzicki T

Exp Gerontol. 2012

Rational engineering of sequence specificity in R.MwoI restriction endonuclease

Skowronek K, Boniecki MJ, Kluge B, Bujnicki JM

Nucleic Acids Res. 2012

Delineation of structural domains and identification of functionally important residues in DNA repair enzyme Exonuclease VII

Poleszak K, Kaminska KH, Dunin-Horkawicz S, Lupas A, Skowronek KJ, Bujnicki JM

Nucleic Acids Res. 2012

Structural bioinformatics of the human spliceosomal proteome

Korneta I, Magnus M, Bujnicki JM

Nucleic Acids Res. 2012

Novel non-specific DNA adenine methyltransferases

Drozdz M, Piekarowicz A, Bujnicki JM, Radlinska M

Nucleic Acids Res. 2012

Sequence-specific cleavage of the RNA strand in DNA-RNA hybrids by the fusion of ribonuclease H with a zinc finger

Sulej AA, Tuszynska I, Skowronek KJ, Nowotny M, Bujnicki JM

Nucleic Acids Res. 2012

The utility of comparative models and the local model quality for protein crystal structure determination by Molecular Replacement

Pawlowski M, Bujnicki JM

BMC Bioinformatics. 2012

RNAmap2D -- calculation, visualization and analysis of contact and distance maps for RNA and protein-RNA complex structures

Pietal MJ, Szostak N, Rother KM, Bujnicki JM

BMC Bioinformatics. 2012

Structural basis of the TAL effector-DNA interaction

Bochtler M

Biol Chem. 2012

Molecular Mechanism of Mutant p53 Stabilization: The Role of HSP70 and MDM2

Wiech M, Olszewski MB, Tracz-Gaszewska Z, Wawrzynow B, Zylicz M, Zylicz A

PLoS One. 2012

Novel beta-catenin target genes identified in thalamic neurons encode modulators of neuronal excitability

Wisniewska MB, Nagalski A, Dabrowski M, Misztal K, Kuznicki J

BMC Genomics. 2012

Anti-staphylococcal activities of lysostaphin and LytM catalytic domain

Sabala I, Jonsson IM, Tarkowski A, Bochtler M

BMC Microbiol. 2012

Crystal structure and mechanism of action of the N6-methyladenine dependent type IIM restriction endonuclease

Siwek W, Czapinska H, Bochtler M, Bujnicki JM, Skowronek K

Nucleic Acids Res. 2012

RPGR mutations might cause reduced orientation of respiratory cilia

Bukowy-Bieryłło Z, Ziętkiewicz E, Loges NT, Wittmer M, Geremek M, Olbrich H, Fliegauf M, Voelkel K, Rutkiewicz E, Rutland J, Morgan L, Pogorzelski A, Martin J, Haan E, Berger W, Omran H, Witt M

Pediatr Pulmonol.. 2012

Prenyltransferases Regulate CD20 Protein Levels and Influence Anti-CD20 Monoclonal Antibody-mediated Activation of Complement-dependent Cytotoxicity

Winiarska M, Nowis D, Bil J, Glodkowska-Mrowka E, Muchowicz A, Wanczyk M, Bojarczuk K, Dwojak M, Firczuk M, Wilczek E, Wachowska M, Roszczenko K, Miaczynska M, Chlebowska J, Basak GW, Golab J

J Biol Chem. 2012

In vivo evidence for cooperation of Mia40 and Erv1 in the oxidation of mitochondrial proteins

Böttinger L*, Gornicka A*, Czerwik T, Bragoszewski P, Loniewska-Lwowska A, Schulze-Specking A, Truscott KN, Guiard B, Milenkovic D, Chacinska A, *equally contributing first author

Mol Biol Cell. 2012

Intermembrane space proteome of yeast mitochondria

Voegtle FN, Burkhart JM, Rao S, Gerbeth C, Hinrichs J, Martinou JC, Chacinska A, Sickmann A, Zahedi RP, Meisinger C

Mol Cell Proteomics. 2012

Role of MINOS in protein biogenesis of the mitochondrial outer membrane

Bohnert M, Wenz LS, Zerbes RM, Horvath SE, Stroud DA, von der Malsburg K, Müller JM, Oeljeklaus S, Perschil I, Warscheid B, Chacinska A, Veenhuis M, van der Klei IJ, Daum G, Wiedemann N, Becker T, Pfanner N, van der Laan M

Mol Biol Cell.. 2012

Functional anatomy of neural circuits regulating fear and extinction

Knapska E, Macias M, Mikosz M, Nowak A, Owczarek D, Wawrzyniak M, Pieprzyk M, Cymerman IA, Werka T, Sheng M, Maren S, Jaworski J, Kaczmarek L

Proc. Natl. Acad. Sci.. 2012

Cytokinesis in Animal Cells

Green RA,Paluch E, Oegema K

Annu Rev Cell Dev Biol.. 2012

Actin cortex mechanics and cellular morphogenesis

Salbreux G, Charras G, Paluch E

Trends Cell Biol.. 2012

Adhesion Functions in Cell Sorting by Mechanically Coupling the Cortices of Adhering Cells

Maître JL, Berthoumieux H, Krens SF, Salbreux G, Jülicher F, Paluch E, Heisenberg CP

Science. 2012

Cell mechanics control rapid transitions between blebs and lamellipodia during migration

Bergert M, Chandradoss SD, Desai RA, Paluch E

Proc Natl Acad Sci U S A. 2012

P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3

Zerrouqi A, Pyrzynska B, Febbraio M, Brat DJ, Van Meir EG

J Clin Invest.. 2012

Alteration of surface properties of dipalmitoyl phosphatidylcholine by benzo[a]pyrene: a model of pulmonary effects of diesel exhaust inhalation

Sosnowski TR, Koliński M, Gradoń L

J Biomed Nanotechnol. 2012

Protein kinase C regulates amino acid transporter ATB

Samluk L, Czeredys M, Skowronek K, Nałęcz KA

Biochem Biophys Res Commun.. 2012

Statins Impair Glucose Uptake in Tumor Cells

Malenda A, Skrobanska A, Issat T, Winiarska M, Bil J, Oleszczak B, Sinski M, Firczuk M, Bujnicki JM, Chlebowska J, Staruch AD, Glodkowska-Mrowka E, Kunikowska J, Krolicki L, Szablewski L, Gaciong Z, Koziak K, Jakobisiak M, Golab J, Nowis DA

Neoplasia. 2012

Crystal structure of 6-SST/6-SFT from Pachysandra terminalis, a plant fructan biosynthesizing enzyme in complex with its acceptor substrate 6-kestose

Lammens W, Le Roy K, Yuan S, Vergauwen R, Rabijns A, Van Laere A, Strelkov SV, Van den Ende W

Plant J.. 2012

Einstein–Hopf drag, Doppler shift of thermal radiation and blackbody drag: Three perspectives on quantum friction

Lach G, DeKievet M, Jentschura UD

Cent. Eur. J. Phys.. 2012

Identification and Regulation of a Molecular Module for Bleb-Based Cell Motility

Goudarzi M, Banisch TU, Mobin MB, Maghelli N, Tarbashevich K, Strate I, van den Berg J, Blaser H, Bandemer S, Paluch E, Bakkers J, Tolić-Nørrelykke IM, Raz E

Dev Cell. 2012

Crystal structures of the tRNA:m(2)G6 methyltransferase Trm14/TrmN from two domains of life

Fislage M, Roovers M, Tuszynska I, Bujnicki JM, Droogmans L, Versées W

Nucleic Acids Res. 2012

RNA-Puzzles: A CASP-like evaluation of RNA three-dimensional structure prediction

Cruz JA, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cao S, Das R, Ding F, Dokholyan NV, Flores SC, Huang L, Lavender CA, Lisi V, Major F, Mikolajczak K, Patel DJ, Philips A, Puton T, Santalucia J, Sijenyi F, Hermann T, Rother K, Rother M, Serganov A, Skorupski M, Soltysinski T, Sripakdeevong P, Tuszynska I, Weeks KM, Waldsich C, Wildauer M, Leontis NB, Westhof E

RNA. 2012

RIBER/DIBER: a software suite for crystal content analysis in the studies of protein-nucleic acid complexes

Chojnowski G, Bujnicki JM, Bochtler M

Bioinformatics. 2012

Highly Pathogenic Alzheimer's Disease Presenilin 1 P117R Mutation Causes a specific Increase in p53 and p21 Protein Levels and Cell Cycle Dysregulation in Human Lymphocytes

Bialopiotrowicz E, Szybinska A, Kuzniewska B, Buizza L, Uberti D, Kuznicki J, Wojda U

J Alzheimers Dis. 2012

Mammalian target of rapamycin complex 1 (MTORC1) and 2 MTORC2) control the dendritic arbor morphology of hippocampal neurons

Urbanska M, Gozdz A, Swiech LJ, Jaworski J

JBC. 2012

APPL1 regulates basal NF-κB activity by stabilizing NIK

Hupalowska A, Pyrzynska B, Miaczynska M

J Cell Sci. 2012

The MIA pathway: A tight bond between protein transport and oxidative folding in mitochondria

Stojanovski D, Bragoszewski P, Chacinska A

BBA-MOL CELL RES. 2012

Related bifunctional restriction endonuclease-methyltransferase triplets: TspDTI, Tth111II/TthHB27I and TsoI with distinct specificities

Zylicz-Stachula A, Zolnierkiewicz O, Lubys A, Ramanauskaite D, Mitkaite G, Bujnicki JM, Skowron P

BMC Mol Biol. 2012

The open reading frame TTC1157 of Thermus thermophilus HB27 encodes the methyltransferase forming N2-methylguanosine at position 6 in tRNA

Roovers M, Oudjama Y, Fislage M, Bujnicki JM, Versées W, Droogmans L

RNA. 2012

Crohn's Disease Risk Alleles on the NOD2 Locus Have Been Maintained by Natural Selection on Standing Variation

Nakagome S, Mano S, Kozlowski L, Bujnicki JM, Shibata H, Fukumaki Y, Kidd JR, Kidd KK, Kawamura S, Oota H

Mol Biol Evol. 2012

Computational methods for prediction of protein-RNA interactions

Puton T, Kozlowski L, Tuszynska I, Rother K, Bujnicki JM

J Struct Biol. 2012

A toolbox for developing bioinformatics software

Rother K, Potrzebowski W, Puton T, Rother M, Wywial E, Bujnicki JM

Brief Bioinform. 2012

The new faces of endocytosis in signaling

Hupalowska A, Miaczynska M

Traffic. 2012

Structure and operation of the DNA-translocating type I DNA restriction enzymes

Kennaway CK, Taylor JE, Song CF, Potrzebowski W, Nicholson W, White JH, Swiderska A,Obarska-Kosinska A, Callow P, Cooper LP, Roberts GA, Artero JB,Bujnicki JM, Trinick J, Kneale GG, Dryden DT

Genes Dev. 2012

MetalionRNA: computational predictor of metal-binding sites in RNA structures

Philips A, Milanowska K, Lach G, Boniecki M, Rother K, Bujnicki JM

Bioinformatics. 2012

The mechanics of the cellular division or how to split a sphere into two?

Tinevez JY, Salbreux G, Paluch E

Med Sci (Paris). 2012

Action of Molecular Switches in GPCRs - Theoretical and Experimental Studies

Trzaskowski B, Latek D, Yuan S, Ghoshdastider U, Debinski A, Filipek S

Curr Med Chem. 2012

Modeling and simulation of cellular functions

Paluch E, El-Samad H

Mol Biol Cell. 2012

Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease

Buizza L, Cenini G, Lanni C, Ferrari-Toninelli G, Prandelli C, Govoni S, Buoso E, Racchi M, Barcikowska M, Styczynska M, Szybinska A, Butterfield DA, Memo M, Uberti D

PLoS One. 2012

Mutations in radial spoke head genes and ultrastructural cilia defects in East-European cohort of primary ciliary dyskinesia patients.

Ziętkiewicz E, Bukowy-Bieryłło Z, Voelkel K, Klimek B, Dmeńska H, Pogorzelski A, Sulikowska-Rowińska A, Rutkiewicz E, Witt M

PLoS One. 2012

Developmental plasticity of the dendritic compartment: focus on the cytoskeleton

Urbanska M, Swiech L, Jaworski J

Adv Exp Med Biol. 2012

DNA methylation pattern is altered in childhood T-cell acute lymphoblastic leukemia patients as compared with normal thymic subsets: insights into CpG island methylator phenotype in T-ALL

Kraszewska MD, Dawidowska M, Kosmalska M, Sędek L, Grzeszczak W, Szczepański T, Witt M

Leukemia. 2012

T-cell acute lymphoblastic leukaemia: recent molecular biology findings

Kraszewska MD, Dawidowska M, Szczepanski T, Witt M

Br J Haematol. 2012

Immunoglobulin/T-cell receptor gene rearrangements in the diagnostic paradigm of pediatric T-cell acute lymphoblastic leukemia patients

Kraszewska MD, Dawidowska M, Kosmalska M, Sędek L, Grzeszczak W, Szczepański T, Witt M

Leukemia & Lymphoma. 2012

Current genetic methodologies in the identification of disaster victims and in forensic analysis

Ziętkiewicz E, Witt M, Daca P, Zebracka-Gala J, Goniewicz M, Jarząb B, Witt M

J Appl Genet.. 2012

Lack of Pur-alpha alters postnatal brain development and causes megalencephaly

Hokkanen S, Feldmann HM, Ding H, Jung CK, Bojarski L, Renner-Müller I, Schüller U, Kretzschmar H, Wolf E, Herms J

Hum Mol Genet.. 2012

2011

Program badawczy PolSenior – cele i metoda

Błędowski P, Mossakowska M, Szybalska A

Zeszyty Naukowe Ochrony Zdrowia. Zdrowie Publiczne i Zarządzanie. 2011

Virtual screening strategies in drug design - methods and applications

Bielska E, Lucas X, Czerwoniec A, Kasprzak JM, Kaminska KH, Bujnicki JM

BioTechnologia. 2011

Modeling of ligand binding to G protein coupled receptors: cannabinoid CB(1), CB (2) and adrenergic β (2)AR.

Audette GF, Lombardo S, Dudzik J, Arruda TM, Kolinski M, Filipek S, Mukerjee S, Kannan AM, Thavasi V, Ramakrishna S, Chin M, Somasundaran P, Viswanathan S, Keles RS, Renugopalakrishnan V

Materials Today. 2011

A high density consensus map of rye (Secale cereale L.) based on DArT markers

Milczarski P, Bolibok-Brągoszewska H, Myśków B, Stojałowski S, Heller-Uszyńska K, Góralska M, Brągoszewski P, Uszyński G, Kilian A, Rakoczy-Trojanowska M

PLoS One. 2011

STAT1 as a novel therapeutical target in pro-atherogenic signal integration of IFNg, TLR4 and IL-6 in vascular disease

Sikorski K, Czerwoniec A, Bujnicki JM, Wesoly J, Bluyssen HAR

Cytokine Growth Factor Rev.. 2011

RNA tertiary structure prediction with ModeRNA

Rother M, Rother K, Puton T, Bujnicki JM

Brief Bioinform. 2011

Databases and bioinformatics tools for the study of DNA repair

Milanowska K, Rother K, Bujnicki JM

Mol Biol Int. 2011

Effect of substrate features and mutagenesis of active site tyrosine residues on the reaction course catalysed by Trypanosoma brucei sterol C-24-methyltransferase

Liu J, Ganapathy K, Wywial E, Bujnicki JM, Nwogwugwu CA, Nes WD

Biochem J. 2011

Identification and modeling of a phosphatase-like domain in a tRNA 2'-O-ribosyl phosphate transferase Rit1p

Czerwoniec A, Bujnicki JM

Cell Cycle. 2011

RNAcentral: A vision for an international database of RNA sequences

Bateman A, Agrawal S, Birney E, Bruford EA, Bujnicki JM, Cochrane G, Cole JR, Dinger ME, Enright AJ, Gardner PP, Gautheret D, Griffiths-Jones S, Harrow J, Herrero J, Holmes IH, Huang HD, Kelly KA, Kersey P, Kozomara A, Lowe TM, Marz M, Moxon S, Pruitt KD, Samuelsson T, Stadler PF, Vilella AJ, Vogel JH, Williams KP, Wright MW, Zwieb C

RNA. 2011

Store-operated calcium entry modulates neuronal network activity in a model of chronic epilepsy

Steinbeck JA, Henke N, Opatz J, Gruszczynska-Biegala J, Schneider L, Theiss S, Hamacher N, Steinfarz B, Golz S, Brüstle O, Kuznicki J, Methner A

Exp Neurol.. 2011

Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex

Schulz C, Lytovchenko O, Melin J, Chacinska A, Guiard B, Neumann P, Ficner R, Jahn O, Schmidt B, Rehling P

J Cell Biol.. 2011

Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis

von der Malsburg K, Müller JM, Bohnert M, Oeljeklaus S, Kwiatkowska P, Becker T, Loniewska-Lwowska A, Wiese S, Rao S, Milenkovic D, Hutu DP, Zerbes RM, Schulze-Specking A, Meyer HE, Martinou JC, Rospert S, Rehling P, Meisinger C, Veenhuis M et all

Dev Cell.. 2011

Importance of single molecular determinants in the fidelity of expanded genetic codes

Antonczak AK, Simova Z, Yonemoto IT, Bochtler M, Piasecka A, Czapinska H, Brancale A, Tippmann EM

Proc Natl Acad Sci U S A.. 2011

The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutières syndrome defects

Figiel M, Chon H, Cerritelli SM, Cybulska M, Crouch RJ, Nowotny M

J Biol Chem. 2011

The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities

Hageman J, van Waarde MA, Zylicz A, Walerych D, Kampinga HH

Biochem J. 2011

ModeRNA: a tool for comparative modeling of RNA 3D structure

Rother M, Rother K, Puton T, Bujnicki JM

Nucleic Acids Res. 2011

Amyloid-associated nucleic acid hybridisation

Braun S, Humphreys C, Fraser E, Brancale A, Bochtler M, Dale TC

PLoS One. 2011

2'-O-ribose methylation of cap2 in human: function and evolution in a horizontally mobile family

Werner M, Purta E, Kaminska KH, Cymerman IA, Campbell DA, Mittra B, Zamudio JR, Sturm NR, Jaworski J, Bujnicki JM

Nucleic Acids Res. 2011

Catalytic mechanism of RNA backbone cleavage by ribonuclease H from quantum mechanics/molecular mechanics simulations

Rosta E, Nowotny M, Yang W, Hummer G

J Am Chem Soc.. 2011

Medical, psychological and socioeconomic aspects of aging in Poland Assumptions and objectives of the PolSenior project

Bledowski P, Mossakowska M, Chudek J, Grodzicki T, Milewicz A, Szybalska A, Wieczorowska-Tobis K, Wiecek A, Bartoszek A, Dabrowski A, Zdrojewski T

Exp Gerontol. 2011

Drug consumption among Polish centenarians

Rajska-Neumann A, Mossakowska M, Klich-Rączka A, Życzkowska J, Grześkowiak E, Shieh S, Wieczorowska-Tobis K

Arch Gerontol Geriatr. 2011

The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins

Becker T, Wenz LS, Krüger V, Lehmann W, Müller JM, Goroncy L, Zufall N, Lithgow T, Guiard B, Chacinska A, Wagner R, Meisinger C, Pfanner N

J Cell Biol.. 2011

DARS-RNP and QUASI-RNP: New statistical potentials for protein-RNA docking

Tuszynska I, Bujnicki JM

BMC Bioinformatics. 2011

Polar actomyosin contractility destabilizes the position of the cytokinetic furrow

Sedzinski J, Biro M, Oswald A, Tinevez JY, Salbreux G, Paluch E

Nature. 2011

Biochemical characterization of APPL endosomes: the role of annexin A2 in APPL membrane recruitment

Urbanska A, Sadowski L, Kalaidzidis Y, Miaczynska M

Traffic. 2011

ModeRNA server: an online tool for modeling RNA 3D structures

Rother M, Milanowska K, Puton T, Jeleniewicz J, Rother K, Bujnicki JM

Bioinformatics. 2011

Rother K, Rother M, Boniecki M, Puton T, Bujnicki JM

Rother K, Rother M, Boniecki M, Puton T, Bujnicki JM

J Mol Model.. 2011

WNT protein-independent constitutive nuclear localization of beta-catenin protein and its low degradation rate in thalamic neurons.

Misztal K, Wisniewska MB, Ambrozkiewicz M, Nagalski A, Kuznicki J

J Biol Chem.. 2011

A single zinc ion is sufficient for an active Trypanosoma brucei tRNA editing deaminase

Spears JL, Rubio MA, Gaston KW, Wywial E, Strikoudis A, Bujnicki JM, Papavasiliou FN, Alfonzo JD

J Biol Chem. 2011

Evidence for an evolutionary antagonism between Mrr and Type III modification systems.

Tesfazgi Mebrhatu M, Wywial E, Ghosh A, Michiels CW, Lindner AB, Taddei F, Bujnicki JM, Van Melderen L, Aertsen A

Nucleic Acids Res. 2011

Template-based and template-free modeling of RNA 3D structure: inspirations from protein structure modeling

Rother K, Rother M, Boniecki M, Puton T, Tomala K, Lukasz P, Bujnicki JM

RNA Structure Prediction and Modelling. 2011

Structure prediction of alternatively spliced proteins

Kozlowski L, Orlowski J, Bujnicki JM

RNA splicing: The complete guide. 2011

In vitro culturing of ciliary respiratory cells--a model for studies of genetic diseases

Bukowy Z, Ziętkiewicz E, Witt M

J Appl Genet. 2011

Gene expression studies in cells from primary ciliary dyskinesia patients identify 208 potential ciliary genes

Geremek M, Bruinenberg M, Ziętkiewicz E, Pogorzelski A, Witt M, Wijmenga C

Hum Genet. 2011

NMDA Receptor Activation Suppresses Microtubule Growth and Spine Entry

Kapitein LC, Yau KW, Gouveia SM, van der Zwan WA, Wulf PS, Keijzer N, Demmers J, Jaworski J, Akhmanova A, Hoogenraad CC

J Neurosci. 2011

Mechanics and regulation of cell shape during the cell cycle

Clark AG, Paluch E

Results Probl Cell Differ. 2011

Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neurons

Perycz M, Urbanska AS, Krawczyk PS, Parobczak K, Jaworski J

J Neurosci. 2011

CLIP-170 and IQGAP1 cooperatively regulate dendrite morphology

Swiech L, Blazejczyk M, Urbanska M, Pietruszka P, Dortland BR, Malik AR, Wulf PS, Hoogenraad CC, Jaworski J

J Neurosci. 2011

Distinct molecular regulation of glycogen synthase kinase-3alpha isozyme controlled by its N-terminal region: functional role in calcium/calpain signaling

Azoulay-Alfaguter I, Yaffe Y, Licht-Murava A, Urbanska M, Jaworski J, Pietrokovski S, Hirschberg K, Eldar-Finkelman H

J Biol Chem. 2011

Structure of UvrA nucleotide excision repair protein in complex with modified DNA.

Jaciuk M, Nowak E, Skowronek K, Tańska A, Nowotny M

Nat Struct Mol Biol. 2011

Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment

Pilecka I, Sadowski L, Kalaidzidis Y, Miaczynska M

Exp Cell Res. 2011

Modeling of ligand binding to G protein coupled receptors: cannabinoid CB(1), CB (2) and adrenergic β (2)AR

Latek D, Kolinski M, Ghoshdastider U, Debinski A, Bombolewski R, Plazinska A, Jozwiak K, Filipek S

J Mol Model. 2011

Arginine interactions with anatase TiO(2) (100) surface and the perturbation of (49)Ti NMR chemical shifts - a DFT investigation: relevance to Renu-Seeram bio solar cell

Koch R, Lipton AS, Filipek S, Renugopalakrishnan V

J Mol Model. 2011

Differential Roles for STIM1 and STIM2 in Store-Operated Calcium Entry in Rat Neurons

Gruszczynska-Biegala J, Pomorski P, Wisniewska MB, Kuznicki J

PLoS One. 2011

Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth

Sobczak A, Debowska K, Blazejczyk M, Kreutz MR, Kuznicki J, Wojda U

Biochim Biophys Acta. 2011

Cell cycle regulation distinguishes lymphocytes from sporadic and familial Alzheimer's disease patients

Bialopiotrowicz E, Kuzniewska B, Kachamakova-Trojanowska N, Barcikowska M, Kuznicki J, Wojda U

Neurobiol Aging. 2011

DNA intercalation without flipping in the specific ThaI-DNA complex

Firczuk M, Wojciechowski M, Czapinska H, Bochtler M

Nucleic Acids Res. 2011

Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit

Husain N, Obranic S, Koscinski L, Seetharaman J, Babic F, Bujnicki JM, Maravic-Vlahovicek G, Sivaraman J

Nucleic Acids Res. 2011

"4D Biology for health and disease" workshop report

Abrahams JP, Apweiler R, Balling R, Bertero MG, Bujnicki JM, Chayen NE, Chène P, Corthals GL, Dyląg T, Förster F, Heck AJ, Henderson PJ, Herwig R, Jehenson P, Kokalj SJ, Laue E, Legrain P, Martens L, Migliorini C, Musacchio A, Podobnik M, Schertler GF, Sc

N Biotechnol. 2011

Hpy188I-DNA pre- and post-cleavage complexes--snapshots of the GIY-YIG nuclease mediated catalysis

Sokolowska M, Czapinska H, Bochtler M

Nucleic Acids Res. 2011

REPAIRtoire-a database of DNA repair pathways

Milanowska K, Krwawicz J, Papaj G, Kosinski J, Poleszak K, Lesiak J, Osinska E, Rother K, Bujnicki JM

Nucleic Acids Res. 2011

2010

BioCatalogue: a universal catalogue of web services for the life sciences

Bhagat J, Tanoh F, Nzuobontane E, Laurent T, Orlowski J, Roos M, Wolstencroft K, Aleksejevs S, Stevens R, Pettifer S, Lopez R, Goble CA

Nucleic Acids Res. 2010

Trm13p, the tRNA:Xm4 modification enzyme from Saccharomyces cerevisiae is a member of the Rossmann-fold MTase superfamily: prediction of structure and active site

Tkaczuk KL

J Mol Model.. 2010

IGERS: inferring Gibbs energy changes of biochemical reactions from reaction similarities

Rother K, Hoffmann S, Bulik S, Hoppe A, Gasteiger J, Holzhütter HG

Biophys J.. 2010

Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms

Zubrienė A, Gutkowska M, Matulienė J, Chaleckis R, Michailovienė V, Voroncova A, Venclovas C, Zylicz A, Zylicz M, Matulis D

Biophys Chem. 2010

The new platinum(IV) derivative LA-12 shows stronger inhibitory effect on Hsp90 function compared to cisplatin

Kvardova V, Hrstka R, Walerych D, Muller P, Matoulkova E, Hruskova V, Stelclova D, Sova P, Vojtesek B

Mol Cancer. 2010

Mitochondrial genotype and breast cancer predisposition

Czarnecka AM, Krawczyk T, Plak K, Klemba A, Zdrozny M, Arnold RS, Kofler B, Golik P, Szybinska A, Lubinski J, Mossakowska M, Bartnik E, Petros JA

Oncol Rep. 2010

Population specificity of the DNAI1 gene mutation spectrum in primary ciliary dyskinesia (PCD)

Ziętkiewicz E, Nitka B, Voelkel K, Skrzypczak U, Bukowy Z, Rutkiewicz E, Humińska K, Przystałowska H, Pogorzelski A, Witt M

Respir Res. 2010

Decreased expression and the Lys751Gln polymorphism of the XPD gene are associated with extreme longevity

Polosak J, Roszkowska-Gancarz M, Kurylowicz A, Owczarz M, Dobosz P, Mossakowska M, Szybinska A, Puzianowska-Kuznicka M

Biogerontology. 2010

An age-related decrease in factor V Leiden frequency among Polish subjects

Adler G, Parczewski M, Czerska E, Loniewska B, Kaczmarczyk M, Gumprecht J, Grzeszczak W, Szybinska A, Mossakowska M, Ciechanowicz A

J Appl Genet. 2010

Mitochondrial genotype in vulvar carcinoma - cuckoo in the nest

Klemba A, Kowalewska M, Kukwa W, Tonska K, Szybinska A, Mossakowska M, Scinska A, Golik P, Koper K, Radziszewski J, Kukwa A, Czarnecka AM, Bartnik E

J Biomed Sci. 2010

The dissection of transcriptional modules regulated by various drugs of abuse in the mouse striatum.

Piechota M, Korostynski M, Solecki W, Gieryk A, Slezak M, Bilecki W, Ziolkowska B, Kostrzewa E, Cymerman I, Swiech L, Jaworski J, Przewlocki R

Genome Biol. 2010

Morgana/CHP-1 is a novel chaperone able to protect cells from stress.

Michowski W, Ferretti R, Wisniewska MB, Ambrozkiewicz M, Beresewicz M, Fusella F, Skibinska-Kijek A, Zablocka B, Brancaccio M, Tarone G, Kuznicki J.

Biochim Biophys Acta. 2010

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain.

Wisniewska MB, Misztal K, Michowski W, Szczot M, Purta E, Lesniak W, Klejman ME, Dabrowski M, Filipkowski RK, Nagalski A, Mozrzymas JW, Kuznicki J.

J Neurosci. 2010

DIBER: protein, DNA or both?

Chojnowski G, Bochtler M

Acta Crystallogr D Biol Crystallogr. 2010

Alu-repeat-induced deletions within the NCF2 gene causing p67-phox-deficient chronic granulomatous disease (CGD)

Gentsch M, Kaczmarczyk A, van Leeuwen K, de Boer M, Kaus-Drobek M, Dagher MC, Kaiser P, Arkwright PD, Gahr M, Rösen-Wolff A, Bochtler M, Secord E, Britto-Williams P, Saifi GM, Maddalena A, Dbaibo G, Bustamante J, Casanova JL, Roos D, Roesler J

Hum Mutat. 2010

1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state

Chojnowski G, Breer K, Narczyk M, Wielgus-Kutrowska B, Czapinska H, Hashimoto M, Hikishima S, Yokomatsu T, Bochtler M, Girstun A, Staroń K, Bzowska A

Biochem Biophys Res Commun. 2010

Control of directed cell migration in vivo by membrane-to-cortex attachment.

Diz-Muñoz A, Krieg M, Bergert M, Ibarlucea-Benitez I, Muller DJ, Paluch E, Heisenberg CP

PLoS Biol. 2010

A putative mobile genetic element carrying a novel type IIF restriction-modification system (PluTI).

Khan F, Furuta Y, Kawai M, Kaminska KH, Ishikawa K, Bujnicki JM, Kobayashi I

Nucleic Acids Res. 2010

Predicting atomic details of the unfolding pathway for YibK, a knotted protein from the SPOUT superfamily

Tuszynska I, Bujnicki JM

J Biomol Struct Dyn. 2010

Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria.

Kaminska KH, Purta E, Hansen LH, Bujnicki JM, Vester B, Long KS

Nucleic Acids Res. 2010

The crystal structure of Escherichia coli spermidine synthase SpeE reveals a unique substrate-binding pocket.

Zhou X, Chua TK, Tkaczuk KL, Bujnicki JM, Sivaraman J

J Struct Biol. 2010

Physiological truncation and domain organization of a novel uracil-DNA-degrading factor.

Pukáncsik M, Békési A, Klement E, Hunyadi-Gulyás E, Medzihradszky KF, Kosinski J, Bujnicki JM, Alfonso C, Rivas G, Vértessy BG

FEBS J. 2010

The YTH domain is a novel RNA binding domain.

Zhang Z, Theler D, Kaminska KH, Hiller M, de la Grange P, Pudimat R, Rafalska I, Heinrich B, Bujnicki JM, Allain FH, Stamm S

J Biol Chem. 2010

Co-evolution-driven switch of J-protein specificity towards an Hsp70 partner.

Pukszta S, Schilke B, Dutkiewicz R, Kominek J, Moczulska K, Stepien B, Reitenga KG, Bujnicki JM, Williams B, Craig EA, Marszalek J

EMBO Rep. 2010

New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA.

Kempenaers M, Roovers M, Oudjama Y, Tkaczuk KL, Bujnicki JM, Droogmans L

Nucleic Acids Res. 2010

Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.

Husain N, Tkaczuk KL, Tulsidas SR, Kaminska KH, Cubrilo S, Maravić-Vlahovicek G, Bujnicki JM, Sivaraman J

Nucleic Acids Res. 2010

Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair.

Kosinski J, Hinrichsen I, Bujnicki JM, Friedhoff P, Plotz G

Hum Mutat. 2010

Crystal structure of a fructokinase homolog from Halothermothrix orenii

Chua TK, Seetharaman J, Kasprzak JM, Ng C, Patel BK, Love C, Bujnicki JM, Sivaraman J

J Struct Biol. 2010

FILTREST3D: discrimination of structural models using restraints from experimental data.

Gajda MJ, Tuszynska I, Kaczor M, Bakulina AY, Bujnicki JM

Bioinformatics. 2010

Production and characterization of recombinant protein preparations of Endonuclease G-homologs from yeast, C. elegans and humans.

Kieper J, Lauber C, Gimadutdinow O, Urbańska A, Cymerman I, Ghosh M, Szczesny B, Meiss G

Protein Expr Purif. 2010

Expression of Ttyh1, a member of the Tweety family in neurons in vitro and in vivo and its potential role in brain pathology.

Stefaniuk M, Swiech L, Dzwonek J, Lukasiuk K

J Neurochem. 2010

Crystal structures of RNase H2 in complex with nucleic acid reveal the mechanism of RNA-DNA junction recognition and cleavage.

Rychlik MP, Chon H, Cerritelli SM, Klimek P, Crouch RJ, Nowotny M

Mol Cell. 2010

Signaling endosomes: seeing is believing

Miaczynska M, Bar-Sagi D

Curr Opin Cell Biol. 2010

Study of a structurally similar kappa opioid receptor agonist and antagonist pair by molecular dynamics simulations.

Kolinski M, Filipek S

J Mol Model. 2010

Physiology and molecular mechanism of glucocorticoid action.

Nagalski A, Kiersztan A.

Postepy Hig Med Dosw. 2010

Resistance of the dopamine D4 receptor to agonist-induced internalization and degradation.

Spooren A, Rondou P, Debowska K, Lintermans B, Vermeulen L, Samyn B, Skieterska K, Debyser G, Devreese B, Vanhoenacker P, Wojda U, Haegeman G, Van Craenenbroeck K.

Cell Signal. 2010

Increased CD44 gene expression in lymphocytes derived from Alzheimer disease patients.

Uberti D, Cenini G, Bonini SA, Barcikowska M, Styczynska M, Szybinska A, Memo M.

Neurodegener Dis. 2010

In vitro findings of alterations in intracellular calcium homeostasis in schizophrenia.

Bojarski L, Debowska K, Wojda U.

Prog Neuropsychopharmacol Biol Psychiatry. 2010

Crystallization of the Photosystem II core complex and its chlorophyll binding subunit CP43 from transplastomic plants of Nicotiana tabacum

Piano D, El Alaoui S, Korza HJ, Filipek R, Sabala I, Haniewicz P, Buechel C, De Sanctis D, Bochtler M

Photosynth Res. 2010

Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.

Kirkegaard T, Roth AG, Petersen NH, Mahalka AK, Olsen OD, Moilanen I, Zylicz A, Knudsen J, Sandhoff K, Arenz C, Kinnunen PK, Nylandsted J, Jäättelä M

Nature. 2010

Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo.

Zurawska A, Urbanski J, Matuliene J, Baraniak J, Klejman MP, Filipek S, Matulis D, Bieganowski P

Biochim Biophys Acta. 2010

ATP binding to Hsp90 is sufficient for effective chaperoning of p53 protein.

Walerych D, Gutkowska M, Klejman MP, Wawrzynow B, Tracz Z, Wiech M, Zylicz M, Zylicz A

J Biol Chem. 2010

2009

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.

Ohya T, Miaczynska M, Coskun U, Lommer B, Runge A, Drechsel D, Kalaidzidis Y, Zerial M

Nature. 2009

[Effectors of GTPase Rab5 in endocytosis and signal transduction]

Olchowik M, Miaczyńska M

Postepy Biochem. 2009

Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex

Banach-Orlowska M, Pilecka I, Torun A, Pyrzynska B, Miaczynska M

Biochem J. 2009

Signaling from endosomes: location makes a difference.

Sadowski L, Pilecka I, Miaczynska M

Exp Cell Res. 2009

Studies of the Activation Steps Concurrent to Ligand Binding in δOR and κOR Opioid Receptors Based on Molecular Dynamics Simulations

M. Kolinfski, S. Filipek

TOSBJ. 2009

CacyBP/SIP binds ERK1/2 and affects transcriptional activity of Elk-1

Kilanczyk E, Filipek S, Jastrzebska B, Filipek A

Biochem Biophys Res Commun. 2009

Generation and characterization of a novel, permanently active S100P mutant.

Austermann J, Nazmi AR, Heil A, Fritz G, Kolinski M, Filipek S, Gerke V

Biochim Biophys Acta. 2009

Study on the feasibility of bacteriorhodopsin as bio-photosensitizer in excitonic solar cell: a first report.

Thavasi V, Lazarova T, Filipek S, Kolinski M, Querol E, Kumar A, Ramakrishna S, Padrós E, Renugopalakrishnan V

J Nanosci Nanotechnol. 2009

Bio-batteries and bio-fuel cells: leveraging on electronic charge transfer proteins.

Kannan AM, Renugopalakrishnan V, Filipek S, Li P, Audette GF, Munukutla L

J Nanosci Nanotechnol. 2009

“Nanomaterials for Energy Convertion Applications”

V. Renugopalakrishnan, A. M. Kannan, S. Srinivasan, V. Thavasi, S. Ramakrishna, P. Li, A. Mershin, S. Filipek, A. Kumar, J. Dutta, A. Jaya, L. Munukutla, S. Velumani, G. F. Audette

\"Nanomaterials for Energy Storage Applications\". 2009

“Bioinformatyka strukturalna białek transbłonowych”

S. Filipek

Kosmos. 2009

Expression of STIM1 in brain and puncta-like co-localization of STIM1 and ORAI1 upon depletion of Ca(2+) store in neurons.

Klejman ME, Gruszczynska-Biegala J, Skibinska-Kijek A, Wisniewska MB, Misztal K, Blazejczyk M, Bojarski L, Kuznicki J.

Neurochem Int. 2009

Immunolocalization of STIM1 in the mouse brain.

Skibinska-Kijek A, Wisniewska MB, Gruszczynska-Biegala J, Methner A, Kuznicki J

Acta Neurobiol Exp (Wars). 2009

Presenilin-dependent expression of STIM proteins and dysregulation of capacitative Ca2+ entry in familial Alzheimer's disease.

Bojarski L, Pomorski P, Szybinska A, Drab M, Skibinska-Kijek A, Gruszczynska-Biegala J, Kuznicki J

Biochim Biophys Acta. 2009

Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA

Sokolowska M, Czapinska H, Bochtler M

Nucleic Acids Res. 2009

Modeling of Escherichia coli Endonuclease V structure in complex with DNA.

Majorek KA, Bujnicki JM

J Mol Model. 2009

The mitotic kinesin-14 Ncd drives directional microtubule-microtubule sliding.

Fink G, Hajdo L, Skowronek KJ, Reuther C, Kasprzak AA, Diez S

Nat Cell Biol. 2009

MODOMICS: a database of RNA modification pathways. 2008 update

Czerwoniec A, Dunin-Horkawicz S, Purta E, Kaminska KH, Kasprzak JM, Bujnicki JM, Grosjean H, Rother K

Nucleic Acids Res. 2009

Functional analysis of MmeI from methanol utilizer Methylophilus methylotrophus, a subtype IIC restriction-modification enzyme related to type I enzymes.

Nakonieczna J, Kaczorowski T, Obarska-Kosinska A, Bujnicki JM

Appl Environ Microbiol. 2009

The structure of M.EcoKI Type I DNA methyltransferase with a DNA mimic antirestriction protein

Kennaway CK, Obarska-Kosinska A, White JH, Tuszynska I, Cooper LP, Bujnicki JM, Trinick J, Dryden DT

Nucleic Acids Res. 2009

Conformation of a plasmid replication initiator protein affects its proteolysis by ClpXP system

Pierechod M, Nowak A, Saari A, Purta E, Bujnicki JM, Konieczny I

Protein Sci. 2009

Medaka: a promising model animal for comparative population genomics.

Matsumoto Y, Oota H, Asaoka Y, Nishina H, Watanabe K, Bujnicki JM, Oda S, Kawamura S, Mitani H

BMC Res Notes. 2009

Fast Structural Alignment of Biomolecules Using a Hash Table, N-Grams and String Descriptors

Bauer RA, Rother K, Moor P, Reinert K, Steinke T, Bujnicki JM

Algorithms. 2009

YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA.

Purta E, O'Connor M, Bujnicki JM, Douthwaite S

Mol Microbiol. 2009

AAN82231 protein from uropathogenic E. coli CFT073 is a close paralog of DsbB enzymes and does not belong to the DsbI family

Pawłowski M, Lasica AM, Jagusztyn-Krynicka EK, Bujnicki JM

Pol J Microbiol. 2009

Cloning and analysis of a bifunctional methyltransferase/restriction endonuclease TspGWI, the prototype of a Thermus sp. enzyme family.

Zylicz-Stachula A, Bujnicki JM, Skowron PM

BMC Mol Biol. 2009

SMN-assisted assembly of snRNP-specific Sm cores in trypanosomes.

Palfi Z, Jaé N, Preusser C, Kaminska KH, Bujnicki JM, Lee JH, Günzl A, Kambach C, Urlaub H, Bindereif A

Genes Dev. 2009

Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase.

Pena V, Jovin SM, Fabrizio P, Orlowski J, Bujnicki JM, Lührmann R, Wahl MC

Mol Cell. 2009

Integrating ELF4 into the circadian system through combined structural and functional studies.

Kolmos E, Nowak M, Werner M, Fischer K, Schwarz G, Mathews S, Schoof H, Nagy F, Bujnicki JM, Davis SJ

HFSP J. 2009

Identification and classification of bcl genes and proteins of Bacillus cereus group organisms and their application in Bacillus anthracis detection and fingerprinting.

Leski TA, Caswell CC, Pawlowski M, Klinke DJ, Bujnicki JM, Hart SJ, Lukomski S

Appl Environ Microbiol. 2009

Mathematical modelling of the influence of heat shock proteins on cancer invasion of tissue.

Szymańska Z, Urbański J, Marciniak-Czochra A

J Math Biol. 2009

Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions.

Walerych D, Olszewski MB, Gutkowska M, Helwak A, Zylicz M, Zylicz A

Oncogene. 2009

Cooperative regulation of the interferon regulatory factor-1 tumor suppressor protein by core components of the molecular chaperone machinery

Narayan V, Eckert M, Zylicz A, Zylicz M, Ball KL

J Biol Chem. 2009

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity.

Jaworski J, Kapitein LC, Gouveia SM, Dortland BR, Wulf PS, Grigoriev I, Camera P, Spangler SA, Di Stefano P, Demmers J, Krugers H, Defilippi P, Akhmanova A, Hoogenraad CC

Neuron. 2009

Biochemical characterization and expression analysis of a novel EF-hand Ca2+ binding protein calmyrin2 (Cib2) in brain indicates its function in NMDA receptor mediated Ca2+ signaling.

Blazejczyk M, Sobczak A, Debowska K, Wisniewska MB, Kirilenko A, Pikula S, Jaworski J, Kuznicki J, Wojda U.

Arch Biochem Biophys. 2009

Structural and functional modules in RNA interference

Nowotny M, Yang W

Curr Opin Struct Biol. 2009

Retroviral integrase superfamily: the structural perspective.

Nowotny M

EMBO Rep. 2009

Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription.

Rashid S, Pilecka I, Torun A, Olchowik M, Bielinska B, Miaczynska M

J Biol Chem. 2009

Endocytic proteins in the regulation of nuclear signaling, transcription and tumorigenesis

Pyrzynska B, Pilecka I, Miaczynska M

Mol Oncol. 2009

Modulation of molecular interactions and function by rhodopsin palmitylation

Park PS, Sapra KT, Jastrzebska B, Maeda T, Maeda A, Pulawski W, Kono M, Lem J, Crouch RK, Filipek S, Müller DJ, Palczewski K

Biochemistry. 2009

Properties of Radical Anions of Triptindanones and Indanones: Electronic Communication and Stability of Ion Pairs Containing Lithium Cations

J.S. Jaworski, A. Kosson, S. Filipek, M. Kolinski, D. Kuck

J. Phys. Chem. C. 2009

The ER and ageing II: calcium homeostasis.

Puzianowska-Kuznicka M, Kuznicki J.

Ageing Res Rev. 2009

A function for the RING finger domain in the allosteric control of MDM2 conformation and activity.

Wawrzynow B, Pettersson S, Zylicz A, Bramham J, Worrall E, Hupp TR, Ball KL

J Biol Chem. 2009

Mathematical modeling of heat shock protein synthesis in response to temperature change.

Szymańska Z, Zylicz M

J Theor Biol. 2009

2008

Sequence analysis of 21 genes located in the Kartagener syndrome linkage region on chromosome 15q

Geremek M, Schoenmaker F, Zietkiewicz E, Pogorzelski A, Diehl S, Wijmenga C, Witt M

Eur J Hum Genet. 2008

Implementation of the standard strategy for identification of Ig/TCR targets for minimal residual disease diagnostics in B-cell precursor ALL pediatric patients: Polish experience

Dawidowska M, Jółkowska J, Szczepański T, Derwich K, Wachowiak J, Witt M

Arch Immunol Ther Exp (Warsz). 2008

Organelle-specific zinc detection using zinpyr-labeled fusion proteins in live cells

Tomat E, Nolan EM, Jaworski J, Lippard SJ

J Am Chem Soc. 2008

Yin Yang 1 is a critical repressor of matrix metalloproteinase-9 expression in brain neurons

Rylski M, Amborska R, Zybura K, Mioduszewska B, Michaluk P, Jaworski J, Kaczmarek L

J Biol Chem. 2008

Microtubule plus-end tracking proteins in differentiated mammalian cells.

Jaworski J, Hoogenraad CC, Akhmanova A

Int J Biochem Cell Biol. 2008

Role of mTOR in physiology and pathology of the nervous system

Swiech L, Perycz M, Malik A, Jaworski J

Biochim Biophys Acta. 2008

Injury induced dendritic plasticity in the mature central nervous system.

Macias M

Acta Neurobiol Exp (Wars). 2008

Molecular basis of dendritic arborization

Urbanska M, Blazejczyk M, Jaworski J

Acta Neurobiol Exp (Wars). 2008

Inducible cAMP early repressor (ICER)-evoked delayed neuronal death in the organotypic hippocampal culture

Mioduszewska B, Jaworski J, Szklarczyk AW, Klejman A, Kaczmarek L

J Neurosci Res. 2008

On the transition from the meiotic to mitotic cell cycle during early mouse development.

Kubiak JZ, Ciemerych MA, Hupalowska A, Sikora-Polaczek M, Polanski Z

Int J Dev Biol. 2008

Mechanisms and functions of endocytosis.

Miaczynska M, Stenmark H

J Cell Biol. 2008

Molecular dynamics of mu opioid receptor complexes with agonists and antagonists

Kolinski M, Filipek S.

The Open Struct. Biol. J.. 2008

Molecular models of the interface between anterior pharynx-defective protein 1 (APH-1) and presenilin involving GxxxG motifs

Jozwiak K, Krzysko KA, Bojarski L, Gacia M, Filipek S

ChemMedChem. 2008

Determination and modelling of stereoselective interactions of ligands with drug transporters: a key dimension in the understanding of drug disposition

Bhatia P, Kolinski M, Moaddel R, Jozwiak K, Wainer IW

Xenobiotica. 2008

Ca2+ -dependent regulation of phototransduction.

Stephen R, Filipek S, Palczewski K, Sousa MC

Photochem Photobiol. 2008

Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy.

Majewski T, Lee S, Jeong J, Yoon DS, Kram A, Kim MS, Tuziak T, Bondaruk J, Lee S, Park WS, Tang KS, Chung W, Shen L, Ahmed SS, Johnston DA, Grossman HB, Dinney CP, Zhou JH, Harris RA, Snyder C, Filipek S, Narod SA, Watson P, Lynch HT, Gazdar A, Bar-Eli M,

Lab Invest. 2008

Variation in NPC1, the gene encoding Niemann-Pick C1, a protein involved in intracellular cholesterol transport, is associated with Alzheimer disease and/or aging in the Polish population

Erickson RP, Larson-Thomé K, Weberg L, Szybinska A, Mossakowska M, Styczynska M, Barcikowska M, Kuznicki J

Neurosci Lett. 2008

Statins impair antitumor effects of rituximab by inducing conformational changes of CD20.

Winiarska M, Bil J, Wilczek E, Wilczynski GM, Lekka M, Engelberts PJ, Mackus WJ, Gorska E, Bojarski L, Stoklosa T, Nowis D, Kurzaj Z, Makowski M, Glodkowska E, Issat T, Mrowka P, Lasek W, Dabrowska-Iwanicka A, Basak GW, Wasik M, Warzocha K, Sinski M, Gaciong Z, Jakobisiak M, Parren PW, Golab J.

PLoS Med. 2008

Polish Centenarians Programme. Multidisciplinary studies of successful ageing: aims, methods, and preliminary results

Mossakowska M, Barcikowska M, Broczek K, Grodzicki T, Klich-Raczka A, Kupisz-Urbanska M, Podsiadly-Marczykowska T, Sikora E, Szybinska A, Wieczorowska-Tobis K, Zyczkowska J, Kuznicki J

Exp Gerontol. 2008

Calcium dysregulation in Alzheimer's disease

Bojarski L, Herms J, Kuznicki J

Neurochem Int. 2008

Calcium ions in neuronal degeneration

Wojda U, Salinska E, Kuznicki J

IUBMB Life. 2008

Conformationally altered p53: a novel Alzheimer's disease marker?

Lanni C, Racchi M, Mazzini G, Ranzenigo A, Polotti R, Sinforiani E, Olivari L, Barcikowska M, Styczynska M, Kuznicki J, Szybinska A, Govoni S, Memo M, Uberti D

Mol Psychiatry. 2008

Sgt1 has co-chaperone properties and is up-regulated by heat shock.

Zabka M, Leśniak W, Prus W, Kuźnicki J, Filipek A

Biochem Biophys Res Commun. 2008

Involvement of S100A6 (calcyclin) and its binding partners in intracellular signaling pathways

Filipek A, Michowski W, Kuznicki J

Adv Enzyme Regul. 2008

Factfile: Calmyrin 1 (review)

Blazejczyk M, Wojda U

Calcium Binding Proteins. 2008

Central base pair flipping and discrimination by PspGI

Szczepanowski RH, Carpenter MA, Czapinska H, Zaremba M, Tamulaitis G, Siksnys V, Bhagwat AS, Bochtler M

Nucleic Acids Res. 2008

How PspGI, catalytic domain of EcoRII and Ecl18kI acquire specificities for different DNA targets

Tamulaitis G, Zaremba M, Szczepanowski RH, Bochtler M, Siksnys V

Nucleic Acids Res. 2008

Thermodynamic studies of interactions of calf spleen PNP with acyclic phosphonate inhibitors

Breer K, Wielgus-Kutrowska B, Hashimoto M, Hikishima S, Yokomatsu T, Szczepanowski RH, Bochtler M, Girstun A, Starón K, Bzowska A

Nucleic Acids Symp Ser (Oxf). 2008

The recognition domain of the BpuJI restriction endonuclease in complex with cognate DNA at 1.3-A resolution

Sukackaite R, Grazulis S, Bochtler M, Siksnys V.

J Mol Biol. 2008

Crystal structure and mechanism of the Staphylococcus cohnii virginiamycin B lyase (Vgb)

Lipka M, Filipek R, Bochtler M

Biochemistry. 2008

Modeling and experimental analyses reveal a two-domain structure and amino acids important for the activity of aminoglycoside resistance methyltransferase Sgm.

Maravić Vlahovicek G, Cubrilo S, Tkaczuk KL, Bujnicki JM

Biochim Biophys Acta. 2008

Structural integrity of the beta beta alpha-Metal finger motif is required for DNA binding and stable protein-DNA complex formation in R.KpnI.

Vasu K, Saravanan M, Bujnicki JM, Nagaraja V

Biochim Biophys Acta. 2008

Structural bioinformatics analysis of enzymes involved in the biosynthesis pathway of the hypermodified nucleoside ms(2)io(6)A37 in tRNA.

Kaminska KH, Baraniak U, Boniecki M, Nowaczyk K, Czerwoniec A, Bujnicki JM

Proteins. 2008

Sequence-structure-function analysis of the bifunctional enzyme MnmC that catalyses the last two steps in the biosynthesis of hypermodified nucleoside mnm5s2U in tRNA.

Roovers M, Oudjama Y, Kaminska KH, Purta E, Caillet J, Droogmans L, Bujnicki JM

Proteins. 2008

Bacteriophage Mu Mom protein responsible for DNA modification is a new member of the acyltransferase superfamily.

Kaminska KH, Bujnicki JM

Cell Cycle. 2008

The TbMTr1 spliced leader RNA cap 1 2'-O-ribose methyltransferase from Trypanosoma brucei acts with substrate specificity

Mittra B, Zamudio JR, Bujnicki JM, Stepinski J, Darzynkiewicz E, Campbell DA, Sturm NR

J Biol Chem. 2008

Virtual screening and experimental verification to identify potential inhibitors of the ErmC methyltransferase responsible for bacterial resistance against macrolide antibiotics.

Feder M, Purta E, Koscinski L, Cubrilo S, Maravic Vlahovicek G, Bujnicki JM

ChemMedChem. 2008

Is AID a monomer in solution?

Bhagwat AS, Carpenter MA, Bujnicki JM

DNA Repair (Amst). 2008

EXOG, a novel paralog of Endonuclease G in higher eukaryotes.

Cymerman IA, Chung I, Beckmann BM, Bujnicki JM, Meiss G

Nucleic Acids Res. 2008

Predicting the complex structure and functional motions of the outer membrane transporter and signal transducer FecA.

Sen TZ, Kloster M, Jernigan RL, Kolinski A, Bujnicki JM, Kloczkowski A

Biophys J. 2008

The structure of sucrose phosphate synthase from Halothermothrix orenii reveals its mechanism of action and binding mode.

Chua TK, Bujnicki JM, Tan TC, Huynh F, Patel BK, Sivaraman J

Plant Cell. 2008

The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK).

Roovers M, Kaminska KH, Tkaczuk KL, Gigot D, Droogmans L, Bujnicki JM

Nucleic Acids Res. 2008

Structural and evolutionary classification of Type II restriction enzymes based on theoretical and experimental analyses.

Orlowski J, Bujnicki JM

Nucleic Acids Res. 2008

Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits.

White J, Li Z, Sardana R, Bujnicki JM, Marcotte EM, Johnson AW

Mol Cell Biol. 2008

The PMS2 subunit of human MutLalpha contains a metal ion binding domain of the iron-dependent repressor protein family.

Kosinski J, Plotz G, Guarné A, Bujnicki JM, Friedhoff P

J Mol Biol. 2008

YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.

Purta E, Kaminska KH, Kasprzak JM, Bujnicki JM, Douthwaite S

RNA. 2008

MetaMQAP: a meta-server for the quality assessment of protein models.

Pawlowski M, Gajda MJ, Matlak R, Bujnicki JM

BMC Bioinformatics. 2008

Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes.

Sunita S, Tkaczuk KL, Purta E, Kasprzak JM, Douthwaite S, Bujnicki JM, Sivaraman J

J Mol Biol. 2008

HsdR subunit of the type I restriction-modification enzyme EcoR124I: biophysical characterisation and structural modelling.

Obarska-Kosinska A, Taylor JE, Callow P, Orlowski J, Bujnicki JM, Kneale GG

J Mol Biol. 2008

YccW is the m5C methyltransferase specific for 23S rRNA nucleotide 1962

Purta E, O\'Connor M, Bujnicki JM, Douthwaite S

J Mol Biol. 2008

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis.

Gyrd-Hansen M, Darding M, Miasari M, Santoro MM, Zender L, Xue W, Tenev T, da Fonseca PC, Zvelebil M, Bujnicki JM, Lowe S, Silke J, Meier P

Nat Cell Biol. 2008

Mutational analysis and a structural model of methyl-directed restriction enzyme Mrr.

Orlowski J, Mebrhatu MT, Michiels CW, Bujnicki JM, Aertsen A

Biochem Biophys Res Commun. 2008

Fhit proteins can also recognize substrates other than dinucleoside polyphosphates.

Guranowski A, Wojdyła AM, Pietrowska-Borek M, Bieganowski P, Khurs EN, Cliff MJ, Blackburn GM, Błaziak D, Stec WJ

FEBS Lett. 2008

The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1.

Sbroggiò M, Ferretti R, Percivalle E, Gutkowska M, Zylicz A, Michowski W, Kuznicki J, Accornero F, Pacchioni B, Lanfranchi G, Hamm J, Turco E, Silengo L, Tarone G, Brancaccio M.

FEBS Lett. 2008

ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1.

Stevens C, Pettersson S, Wawrzynow B, Wallace M, Ball K, Zylicz A, Hupp TR

FEBS J. 2008

Hsp90n - An accidental product of a fortuitous chromosomal translocation rather than a regular Hsp90 family member of human proteome

Zurawska A, Urbanski J, Bieganowski P

Biochim Biophys Acta. 2008

2007

The nutritional habits among centenarians living in Warsaw

Kołłajtis-Dołowy A, Pietruszka B, Kałuza J, Pawlińiska-Chmara R, Broczek K, Mossakowska M

Rocz Panstw Zakl Hig. 2007

Evaluation of neuroendocrine status in longevity

Baranowska B, Wolinska-Witort E, Bik W, Baranowska-Bik A, Martynska L, Broczek K, Mossakowska M, Chmielowska M

Neurobiol Aging. 2007

Effects of age and gender on micronucleus and chromosome nondisjunction frequencies in centenarians and younger subjects

Wojda A, Zietkiewicz E, Witt M

Mutagenesis. 2007

ARF6 in the nervous system.

Jaworski J

Eur J Cell Biol. 2007

Beta-dystroglycan as a target for MMP-9, in response to enhanced neuronal activity.

Michaluk P, Kolodziej L, Mioduszewska B, Wilczynski GM, Dzwonek J, Jaworski J, Gorecki DC, Ottersen OP, Kaczmarek L

J Biol Chem. 2007

TIMP-1 abolishes MMP-9-dependent long-lasting long-term potentiation in the prefrontal cortex.

Okulski P, Jay TM, Jaworski J, Duniec K, Dzwonek J, Konopacki FA, Wilczynski GM, Sánchez-Capelo A, Mallet J, Kaczmarek L

Biol Psychiatry. 2007

Nuclear functions of endocytic proteins

Pilecka I, Banach-Orlowska M, Miaczynska M

Eur J Cell Biol. 2007

Early-onset Alzheimer's disease with a de novo mutation in the presenilin 1 gene

Golan MP, Styczyńska M, Jóźwiak K, Walecki J, Maruszak A, Pniewski J, Lugiewicz R, Filipek S, Zekanowski C, Barcikowska M

Exp Neurol. 2007

Molecular modelling of the complex of oligomeric rhodopsin and its G protein.

Krzysko KA, Kolinski M, Filipek S.

J Phys Condens Matter. 2007

Forerunner genes contiguous to RB1 contribute to the development of in situ neoplasia.

Lee S, Jeong J, Majewski T, Scherer SE, Kim MS, Tuziak T, Tang KS, Baggerly K, Grossman HB, Zhou JH, Shen L, Bondaruk J, Ahmed SS, Samanta S, Spiess P, Wu X, Filipek S, McConkey D, Bar-Eli M, Issa JP, Benedict WF, Czerniak B

Proc Natl Acad Sci U S A. 2007

Stabilizing effect of Zn2+ in native bovine rhodopsin

Park PS, Sapra KT, Koliński M, Filipek S, Palczewski K, Muller DJ

J Biol Chem. 2007

Biochemical properties of endogenous presenilin 1 and presenilin 2 in cultured human B-lymphocytes

Bojarski L, Lewandowicz A, Blazejczyk M, Sobczak A, Kuznicki J, Wojda U

Clin Chem Lab Med. 2007

Epigenetic control of the S100A6 (calcyclin) gene expression

Leśniak W, Słomnicki ŁP, Kuźnicki J

J Invest Dermatol. 2007

CacyBP/SIP interacts with tubulin in neuroblastoma NB2a cells and induces formation of globular tubulin assemblies

Schneider G, Nieznanski K, Kilanczyk E,Bieganowski P, Kuznicki J, Filipek A

Biochim Biophys Acta. 2007

Hsp70 is a new target of Sgt1-an interaction modulated by S100A6

Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J,Filipek A

Biochem Biophys Res Commun. 2007

Association study of cholesterol-related genes in Alzheimer's disease

Wollmer MA, Sleegers K, Ingelsson M, Zekanowski C, Brouwers N, Maruszak A, Brunner F, Huynh KD, Kilander L, Brundin RM, Hedlund M, Giedraitis V, Glaser A, Engelborghs S, De Deyn PP, Kapaki E, Tsolaki M, Daniilidou M, Molyva D, Paraskevas GP, Thal DR, Barcikowska M, Kuznicki J, Lannfelt L, Van Broeckhoven C, Nitsch RM, Hock C, Papassotiropoulos A.

Neurogenetics. 2007

The highest reflection intensity in a resolution shell

Bochtler M, Chojnowski G

Acta Crystallogr A. 2007

The statistics of the highest E value

Chojnowski G, Bochtler M

Acta Crystallogr A. 2007

Folds and activities of peptidoglycan amidases

Firczuk M, Bochtler M

FEMS Microbiol Rev. 2007

Mutational analysis of peptidoglycan amidase MepA

Firczuk M, Bochtler M

Biochemistry. 2007

Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically

Kaus-Drobek M, Czapinska H, Sokołowska M, Tamulaitis G, Szczepanowski RH, Urbanke C, Siksnys V, Bochtler M

Nucleic Acids Res. 2007

Restriction endonucleases that resemble a component of the bacterial DNA repair machinery

Sokolowska M, Kaus-Drobek M, Czapinska H, Tamulaitis G, Siksnys V, Bochtler M

Cell Mol Life Sci. 2007

Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA.

Sokolowska M, Kaus-Drobek M, Czapinska H, Tamulaitis G, Szczepanowski RH, Urbanke C, Siksnys V, Bochtler M

J Mol Biol. 2007

Nucleotide flipping by restriction enzymes analyzed by 2-aminopurine steady-state fluorescence

Tamulaitis G, Zaremba M, Szczepanowski RH, Bochtler M, Siksnys V

Nucleic Acids Res. 2007

The 2'-O-ribose methyltransferase for cap 1 of spliced leader RNA and U1 small nuclear RNA in Trypanosoma brucei

Zamudio JR, Mittra B, Foldynová-Trantírková S, Zeiner GM, Lukes J, Bujnicki JM, Sturm NR, Campbell DA

Mol Cell Biol. 2007

Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.

Tkaczuk KL, Dunin-Horkawicz S, Purta E, Bujnicki JM

BMC Bioinformatics. 2007

Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC.

Sunita S, Purta E, Durawa M, Tkaczuk KL, Swaathi J, Bujnicki JM, Sivaraman J

Nucleic Acids Res. 2007

Human lysosomal DNase IIalpha contains two requisite PLD-signature (HxK) motifs: evidence for a pseudodimeric structure of the active enzyme species.

Schäfer P, Cymerman IA, Bujnicki JM, Meiss G

Protein Sci. 2007

SURF'S UP! - protein classification by surface comparisons

Sasin JM, Godzik A, Bujnicki JM

J Biosci. 2007

Transcriptome profile of human colorectal adenomas.

Sabates-Bellver J, Van der Flier LG, de Palo M, Cattaneo E, Maake C, Rehrauer H, Laczko E, Kurowski MA, Bujnicki JM, Menigatti M, Luz J, Ranalli TV, Gomes V, Pastorelli A, Faggiani R, Anti M, Jiricny J, Clevers H, Marra G

Mol Cancer Res. 2007

PROTMAP2D: visualization, comparison and analysis of 2D maps of protein structure.

Pietal MJ, Tuszynska I, Bujnicki JM

Bioinformatics. 2007

Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa.

Pena V, Liu S, Bujnicki JM, Lührmann R, Wahl MC

Mol Cell. 2007

Conserved amino acids in each subunit of the heteroligomeric tRNA m1A58 Mtase from Saccharomyces cerevisiae contribute to tRNA binding.

Ozanick SG, Bujnicki JM, Sem DS, Anderson JT

Nucleic Acids Res. 2007

I-Ssp6803I: the first homing endonuclease from the PD-(D/E)XK superfamily exhibits an unusual mode of DNA recognition

Orlowski J, Boniecki M, Bujnicki JM

Bioinformatics. 2007

Novel protein fold discovered in the PabI family of restriction enzymes.

Miyazono K, Watanabe M, Kosinski J, Ishikawa K, Kamo M, Sawasaki T, Nagata K, Bujnicki JM, Endo Y, Tanokura M, Kobayashi I

Nucleic Acids Res. 2007

Structure and evolutionary origin of Ca(2+)-dependent herring type II antifreeze protein.

Liu Y, Li Z, Lin Q, Kosinski J, Seetharaman J, Bujnicki JM, Sivaraman J, Hew CL

PLoS One. 2007

[Probing of contacts between EcoRII DNA methyltransferase and DNA using substrate analogs and molecular modeling].

Kudan EV, Brevnov MG, Subach OM, Rechkoblit OA, Buĭnitskiĭ IaM, Gromova ES

Mol Biol (Mosk). 2007

A model of restriction endonuclease MvaI in complex with DNA: a template for interpretation of experimental data and a guide for specificity engineering.

Kosinski J, Kubareva E, Bujnicki JM

Proteins. 2007

Identification of a missing sequence and functionally important residues of 16S rRNA:m(1)A1408 methyltransferase KamB that causes bacterial resistance to aminoglycoside antibiotics.

Koscinski L, Feder M, Bujnicki JM

Cell Cycle. 2007

Identification of a single HNH active site in type IIS restriction endonuclease Eco31I

Jakubauskas A, Giedriene J, Bujnicki JM, Janulaitis A

J Mol Biol. 2007

Type II restriction endonuclease R.Eco29kI is a member of the GIY-YIG nuclease superfamily.

Ibryashkina EM, Zakharova MV, Baskunov VB, Bogdanova ES, Nagornykh MO, Den\'mukhamedov MM, Melnik BS, Kolinski A, Gront D, Feder M, Solonin AS, Bujnicki JM

BMC Struct Biol. 2007

Phylogenetic analysis of haloalkane dehalogenases.

Chovancová E, Kosinski J, Bujnicki JM, Damborský J

Proteins. 2007

CacyBP/SIP interacts with tubulin in neuroblastoma NB2a cells and induces formation of globular tubulin assemblies.

Schneider G, Nieznanski K, Kilanczyk E, Bieganowski P, Kuznicki J, Filipek A

Biochim Biophys Acta. 2007

MDM2 chaperones the p53 tumor suppressor.

Wawrzynow B, Zylicz A, Wallace M, Hupp T, Zylicz M

J Biol Chem. 2007

Hsp70 is a new target of Sgt1--an interaction modulated by S100A6

Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J, Filipek A

Biochem Biophys Res Commun. 2007

Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.

Issat T, Nowis D, Legat M, Makowski M, Klejman MP, Urbanski J, Skierski J, Koronkiewicz M, Stoklosa T, Brzezinska A, Bil J, Gietka J, Jakóbisiak M, Golab J

Int J Oncol. 2007

CacyBP/SIP interacts with tubulin in neuroblastoma NB2a cells and induces formation of globular tubulin assemblies.

Schneider G, Nieznanski K, Kilanczyk E, Bieganowski P, Kuznicki J, Filipek A

Biochim Biophys Acta. 2007

MDM2 chaperones the p53 tumor suppressor.

Wawrzynow B, Zylicz A, Wallace M, Hupp T, Zylicz M

J Biol Chem. 2007

Hsp70 is a new target of Sgt1--an interaction modulated by S100A6.

Spiechowicz M, Zylicz A, Bieganowski P, Kuznicki J, Filipek A

Biochem Biophys Res Commun. 2007

Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.

Issat T, Nowis D, Legat M, Makowski M, Klejman MP, Urbanski J, Skierski J, Koronkiewicz M, Stoklosa T, Brzezinska A, Bil J, Gietka J, Jakóbisiak M, Golab J

Int J Oncol. 2007

2006

Physical activity in Polish centenarians

Kupisz-Urbańska M, Broczek K, Mossakowska M

Gerontologia Polska. 2006

How often and how much have Polish centenarians smoked?

Mossakowska M, Broczek K, Rajska-Neumann A, Wieczorowska-Tobis K

Przegląd Lekarski. 2006

Evaluation of teeth and dentures state of Polish centenarians

Pawlinska-Chmara R, Mossakowska M

Ann Univ M. Curie-Sklodowska. 2006

The analysis of the peripheral blood leukocytes in centenarians

Podkówka-Sieczka R, Niemir Z, Mossakowska M, Sawiński K, Wieczorowska-Tobis K

Przegląd Lekarski. 2006

Is there a link between the level of circulating IL-8 and cognitive impairment in centenarians?

Styczyński A, Wieczorowska-Tobis K, Niemir Z, Podkówka R, Mossakowska M

Przegląd Lekarski. 2006

Can an increased level of circulating IL-8 be a predictor of human longevity?

Wieczorowska-Tobis K, Niemir ZI, Podkówka R, Korybalska K, Mossakowska M, Breborowicz A

Med Sci Monit. 2006

Correlation between the level of cytogenetic aberrations in cultured human lymphocytes and the age and gender of donors

Wojda A, Zietkiewicz E, Mossakowska M, Pawłowski W, Skrzypczak K, Witt M

J Gerontol A Biol Sci Med Sci. 2006

Characteristics of nutrition among centenarians living in Warsaw

Pietruszka B, Kollajtis-Dolowy A, Szulc K, Kaluza J, Broczek K, Pawlinska-Chmara R, Mossakowska M

Pol J Food Nutr Sci. 2006

Functional abilities and antioxidant defense status in female centenarians

Kempa K, Kłapcińska B, Mossakowska M, Broczek K, Sadowska-Krępa E, Derejczyk J, Kimsa E

Annales Universitatis Mariae Curie-Skłaodowska. 2006

Glutamine-dependent NAD+ synthetase. How a two-domain, three-substrate enzyme avoids waste.

Wojcik M, Seidle HF, Bieganowski P, Brenner C

J Biol Chem. 2006

The growing role of mTOR in neuronal development and plasticity

Jaworski J, Sheng M

Mol Neurobiol. 2006

Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization.

Nolan EM, Ryu JW, Jaworski J, Feazell RP, Sheng M, Lippard SJ

J Am Chem Soc. 2006

Increased estrogen receptor beta expression correlates with decreased spine formation in the rat hippocampus

Szymczak S, Kalita K, Jaworski J, Mioduszewska B, Savonenko A, Markowska A, Merchenthaler I, Kaczmarek L

Hippocampus. 2006

Pulling single bacteriorhodopsin out of a membrane: Comparison of simulation and experiment.

Cieplak M, Filipek S, Janovjak H, Krzyśko KA

Biochim Biophys Acta. 2006

Linear patterns of Alzheimer's disease mutations along alpha-helices of presenilins as a tool for PS-1 model construction

Jozwiak K, Zekanowski C, Filipek S

J Neurochem. 2006

Arrestin interaction with rhodopsin: conceptual models.

Modzelewska A, Filipek S, Palczewski K, Park PS

Cell Biochem Biophys. 2006

Detecting molecular interactions that stabilize native bovine rhodopsin

Tanuj Sapra K, Park PS, Filipek S, Engel A, Müller DJ, Palczewski K

J Mol Biol. 2006

Two novel presenilin 1 gene mutations connected with frontotemporal dementia-like clinical phenotype: genetic and bioinformatic assessment.

Zekanowski C, Golan MP, Krzyśko KA, Lipczyńska-Łojkowska W, Filipek S, Kowalska A, Rossa G, Pepłońska B, Styczyńska M, Maruszak A, Religa D, Wender M, Kulczycki J, Barcikowska M, Kuźnicki J.

Exp Neurol.. 2006

Autosomal recessive retinitis pigmentosa and E150K mutation in the opsin gene.

Zhu L, Imanishi Y, Filipek S, Alekseev A, Jastrzebska B, Sun W, Saperstein DA, Palczewski K

J Biol Chem. 2006

Electrostatic model of bond dissociation energies in polyhalogen methanes

Jaworski JS, Cembor M, Koliński M

J Phys Org Chem. 2006

Calretinin, an EF-hand calcium-binding proteins, binds zinc and Cooper

Groves P, Palczewska M, Kuznicki J

Calcium Binding Proteins. 2006

Binding and functional characteristics of two E-box motifs within the S100A6 (calcyclin) gene promoter.

Leśniak W, Kuźnicki J

J Cell Biochem. 2006

Density of Sgt1-immunopositive neurons is decreased in the cerebral cortex of Alzheimer's disease brain.

Spiechowicz M, Bernstein HG, Dobrowolny H, Leśniak W, Mawrin C, Bogerts B, Kuźnicki J, Filipek A

Neurochem Int. 2006

Neuroendocrine control of metabolic homeostasis in Polish centenarians

Baranowska B, Bik W, Baranowska-Bik A, Wolinska-Witort E, Szybinska A, Martynska L, Chmielowska M

J Physiol Pharmacol. 2006

The relationship between adiponectin levels and metabolic status in centenarian, early elderly, young and obese women

Bik W, Baranowska-Bik A, Wolinska-Witort E, Martynska L, Chmielowska M, Szybinska A, Broczek K, Baranowska B

Neuro Endocrinol Lett. 2006

Ca2+-independent binding and cellular expression profiles question a significant role of calmyrin in transduction of Ca2+-signals to Alzheimer's disease-related presenilin 2 in forebrain

Blazejczyk M, Wojda U, Sobczak A, Spilker C, Bernstein HG, Gundelfinger ED, Kreutz MR, Kuznicki J

Biochim Biophys Acta. 2006

Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease

Bochtler M, Szczepanowski RH, Tamulaitis G, Grazulis S, Czapinska H, Manakova E, Siksnys V

EMBO J. 2006

Crystal structure of Bacillus subtilis TrmB, the tRNA (m7G46) methyltransferase.

Zegers I, Gigot D, van Vliet F, Tricot C, Aymerich S, Bujnicki JM, Kosinski J, Droogmans L

Nucleic Acids Res. 2006

Complete cap 4 formation is not required for viability in Trypanosoma brucei.

Zamudio JR, Mittra B, Zeiner GM, Feder M, Bujnicki JM, Sturm NR, Campbell DA

Eukaryot Cell. 2006

Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis.

Tkaczuk KL, Obarska A, Bujnicki JM

BMC Evol Biol. 2006

Theoretical model of restriction endonuclease HpaI in complex with DNA, predicted by fold recognition and validated by site-directed mutagenesis.

Skowronek KJ, Kosinski J, Bujnicki JM

Proteins. 2006

Curcumin induces caspase-3-dependent apoptotic pathway but inhibits DNA fragmentation factor 40/caspase-activated DNase endonuclease in human Jurkat cells.

Sikora E, Bielak-Zmijewska A, Magalska A, Piwocka K, Mosieniak G, Kalinowska M, Widlak P, Cymerman IA, Bujnicki JM

Mol Cancer Ther. 2006

Evaluation of molecular models for the affinity maturation of antibodies: roles of cytosine deamination by AID and DNA repair.

Samaranayake M, Bujnicki JM, Carpenter M, Bhagwat AS

Chem Rev. 2006

The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase.

Purta E, van Vliet F, Tkaczuk KL, Dunin-Horkawicz S, Mori H, Droogmans L, Bujnicki JM

BMC Mol Biol. 2006

Structural model for the multisubunit Type IC restriction-modification DNA methyltransferase M.EcoR124I in complex with DNA.

Obarska A, Blundell A, Feder M, Vejsadová S, Sisáková E, Weiserová M, Bujnicki JM, Firman K

Nucleic Acids Res. 2006

Casein kinases phosphorylate multiple residues spanning the entire hnRNP K length.

Mikula M, Karczmarski J, Dzwonek A, Rubel T, Hennig E, Dadlez M, Bujnicki JM, Bomsztyk K, Ostrowski J

Biochim Biophys Acta. 2006

The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol.

Metz J, Wächter A, Schmidt B, Bujnicki JM, Schwappach B

J Biol Chem. 2006

Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa.

Klimek-Tomczak K, Mikula M, Dzwonek A, Paziewska A, Karczmarski J, Hennig E, Bujnicki JM, Bragoszewski P, Denisenko O, Bomsztyk K, Ostrowski J

Br J Cancer. 2006

Binding of the low-density lipoprotein by streptococcal collagen-like protein Scl1 of Streptococcus pyogenes.

Han R, Caswell CC, Lukomska E, Keene DR, Pawlowski M, Bujnicki JM, Kim JK, Lukomski S

Mol Microbiol. 2006

Characterization of prmt7alpha and beta isozymes from Chinese hamster cells sensitive and resistant to topoisomerase II inhibitors.

Gros L, Renodon-Cornière A, de Saint Vincent BR, Feder M, Bujnicki JM, Jacquemin-Sablon A

Biochim Biophys Acta. 2006

Helicobacter pylori protein oxidation influences the colonization process.

Godlewska R, Dzwonek A, Mikuła M, Ostrowski J, Pawłowski M, Bujnicki JM, Jagusztyn-Krynicka EK

Int J Med Microbiol. 2006

THUMP from archaeal tRNA:m22G10 methyltransferase, a genuine autonomously folding domain.

Gabant G, Auxilien S, Tuszynska I, Locard M, Gajda MJ, Chaussinand G, Fernandez B, Dedieu A, Grosjean H, Golinelli-Pimpaneau B, Bujnicki JM, Armengaud J

Nucleic Acids Res. 2006

Phylogenomic analysis of the GIY-YIG nuclease superfamily.

Dunin-Horkawicz S, Feder M, Bujnicki JM

BMC Genomics. 2006

Identification of a new subfamily of HNH nucleases and experimental characterization of a representative member, HphI restriction endonuclease

Cymerman IA, Obarska A, Skowronek KJ, Lubys A, Bujnicki JM

Proteins. 2006

Malaria: therapy, genes and vaccines.

Chiang PK, Bujnicki JM, Su X, Lanar DE

Curr Mol Med. 2006

Sequence-dependent enhancement of hydrolytic deamination of cytosines in DNA by the restriction enzyme PspGI.

Carpenter M, Divvela P, Pingoud V, Bujnicki J, Bhagwat AS

Nucleic Acids Res. 2006

Protein-structure prediction by recombination of fragments.

Bujnicki JM

Chembiochem. 2006

Functional analysis of amino acid residues at the dimerisation interface of KpnI DNA methyltransferase.

Bheemanaik S, Bujnicki JM, Nagaraja V, Rao DN

Biol Chem. 2006

MODOMICS: a database of RNA modification pathways.

Dunin-Horkawicz S, Czerwoniec A, Gajda MJ, Feder M, Grosjean H, Bujnicki JM

Nucleic Acids Res. 2006

High guanine and cytosine content increases mRNA levels in mammalian cells

Kudla G, Lipinski L, Caffin F, Helwak A, Zylicz M

PLoS Biol. 2006

Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis.

Galazka G, Stasiolek M, Walczak A, Jurewicz A, Zylicz A, Brosnan CF, Raine CS, Selmaj KW

J Immunol. 2006

Synthetic lethal and biochemical analyses of NAD and NADH kinases in Saccharomyces cerevisiae establish separation of cellular functions.

Bieganowski P, Seidle HF, Wojcik M, Brenner C

J Biol Chem. 2006

Glutamine-dependent NAD+ synthetase. How a two-domain, three-substrate enzyme avoids waste.

Wojcik M, Seidle HF, Bieganowski P, Brenner C

J Biol Chem. 2006

High guanine and cytosine content increases mRNA levels in mammalian cells

Kudla G, Lipinski L, Caffin F, Helwak A, Zylicz M

PLoS Biol. 2006

Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis.

Galazka G, Stasiolek M, Walczak A, Jurewicz A, Zylicz A, Brosnan CF, Raine CS, Selmaj KW

J Immunol. 2006

2005

Hematopoietic chimerism after allogeneic stem cell transplantation: a comparison of quantitative analysis by automated DNA sizing and fluorescent in situ hybridization

Jólkowska J, Pieczonka A, Strabel T, Boruczkowski D, Wachowiak J, Bader P, Witt M

BMC Blood Disord. 2005

Anthropometric chest structure of Polish centenarians

Broczek KM, Pawlińska-Chmara R, Kupisz-Urbańska M, Mossakowska M

J Physiol Pharmacol. 2005

Organization of rhodopsin molecules in native membranes of rod cells--an old theoretical model compared to new experimental data.

Filipek S

J Mol Model. 2005

Functional oligomers of rhodopsin – a G protein-coupled receptor template

Filipek S, Modzelewska A, Krzysko KA

Joint Meeting on Medical Chemistry. 2005

A novel GCAP1 missense mutation (L151F) in a large family with autosomal dominant cone-rod dystrophy (adCORD)

Sokal I, Dupps WJ, Grassi MA, Brown J Jr, Affatigato LM, Roychowdhury N, Yang L, Filipek S, Palczewski K, Stone EM, Baehr W

Invest Ophthalmol Vis Sci. 2005

The Alzheimer disease-related calcium-binding protein Calmyrin is present in human forebrain with an altered distribution in Alzheimer's as compared to normal ageing brains

Bernstein HG, Blazejczyk M, Rudka T, Gundelfinger ED, Dobrowolny H, Bogerts B, Kreutz MR, Kuznicki J, Wojda U

Neuropathol Appl Neurobiol. 2005

The modular structure of SIP facilitates its role in stabilizing multiprotein assemblies

Bhattacharya S, Lee YT, Michowski W, Jastrzebska B, Filipek A, Kuznicki J, Chazin WJ

Biochemistry. 2005

Calcyclin (S100A6) expression is stimulated by agents evoking oxidative stress via the antioxidant response element.

Leśniak W, Szczepańska A, Kuźnicki J.

Biochim Biophys Acta. 2005

Characterization of calretinin I-II as an EF-hand, Ca2+, H+-sensing domain

Palczewska M, Batta G, Groves P, Linse S, Kuznicki J

Protein Sci. 2005

Genetic alterations in accelerated ageing syndromes. Do they play a role in natural ageing?

Puzianowska-Kuznicka M, Kuznicki J.

Int J Biochem Cell Biol. 2005

Calcium-binding calmyrin forms stable covalent dimers in vitro, but in vivo is found in monomeric form.

Sobczak A, Blazejczyk M, Piszczek G, Zhao G, Kuznicki J, Wojda U.

Acta Biochim Pol. 2005

The -22c/t polymorphism in presenilin 1 gene is not connected with late-onset and early-onset familial Alzheimer's disease in Poland

Zekanowski C, Religa D, Safranow K, Maruszak A, Dziedziejko V, Styczyńska M, Gacia M, Golan M, Pepłońska B, Chlubek D, Kuźnicki J, Barcikowska M

J Neural Transm. 2005

Characterization of the HslU chaperone affinity for HslV protease

Azim MK, Goehring W, Song HK, Ramachandran R, Bochtler M, Goettig P

Protein Sci. 2005

Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene

Dandanell G,Szczepanowski RH, Kierdaszuk B, Shugar D, Bochtler M

J Mol Biol. 2005

A comparison of staphostatin B with standard mechanism serine protease inhibitors

Filipek R, Potempa J, Bochtler M

J Biol Chem. 2005

Crystal structures of active LytM

Firczuk M, Mucha A, Bochtler M

J Mol Biol. 2005

Structure of the metal-independent restriction enzyme BfiI reveals fusion of a specific DNA-binding domain with a nonspecific nuclease.

Grazulis S, Manakova E, Roessle M, Bochtler M, Tamulaitiene G, Huber R, Siksnys V

Proc Natl Acad Sci U S A. 2005

Molecular machines for protein degradation.

Groll M, Bochtler M, Brandstetter H, Clausen T, Huber R

Chembiochem. 2005

Pseudomonas aeruginosa LD-carboxypeptidase, a serine peptidase with a Ser-His-Glu triad and a nucleophilic elbow.

Korza HJ, Bochtler M

J Biol Chem. 2005

Staphylococcus aureus aminopeptidase S is a founding member of a new peptidase clan

Odintsov SG, Sabała I, Bourenkov G, Rybin V, Bochtler M

J Biol Chem. 2005

Substrate access to the active sites in aminopeptidase T, a representative of a new metallopeptidase clan.

Odintsov SG, Sabała I, Bourenkov G, Rybin V, Bochtler M

J Mol Biol. 2005

Crystal structure of a fragment of mouse ubiquitin-activating enzyme.

Szczepanowski RH, Filipek R, Bochtler M

J Biol Chem. 2005

Fighting an enemy within: cytoplasmic inhibitors of bacterial cysteine proteases

Potempa J, Golonka E, Filipek R, Shaw LN

Mol Microbiol. 2005

Peptydoglycan amidase MepA is a LAS metallopeptidase

Marcyjaniak M, Odintsov SG, Sabala I, Bochtler M

J Biol Chem. 2005

Cloning and preliminary characterization of a GATC-specific beta2-class DNA:m6A methyltransferase encoded by transposon Tn1549 from Enterococcus spp.

Radlińska M, Piekarowicz A, Galimand M, Bujnicki JM

Pol J Microbiol. 2005

Identification of amino acids important for target recognition by the DNA:m5C methyltransferase M.NgoPII by alanine-scanning mutagenesis of residues at the protein-DNA interface.

Radlinska M, Kondrzycka-Dada A, Piekarowicz A, Bujnicki JM

Proteins. 2005

Characterization of new DsbB-like thiol-oxidoreductases of Campylobacter jejuni and Helicobacter pylori and classification of the DsbB family based on phylogenomic, structural and functional criteria.

Raczko AM, Bujnicki JM, Pawlowski M, Godlewska R, Lewandowska M, Jagusztyn-Krynicka EK

Microbiology. 2005

Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA.

Purushothaman SK, Bujnicki JM, Grosjean H, Lapeyre B

Mol Cell Biol. 2005

Analysis of the quaternary structure of the MutL C-terminal domain.

Kosinski J, Steindorf I, Bujnicki JM, Giron-Monzon L, Friedhoff P

J Mol Biol. 2005

FRankenstein becomes a cyborg: the automatic recombination and realignment of fold recognition models in CASP6.

Kosinski J, Gajda MJ, Cymerman IA, Kurowski MA, Pawlowski M, Boniecki M, Obarska A, Papaj G, Sroczynska-Obuchowicz P, Tkaczuk KL, Sniezynska P, Sasin JM, Augustyn A, Bujnicki JM, Feder M

Proteins. 2005

Molecular modeling of a psychrophilic β-galactosidase

Tkaczuk KL, Bujnicki JM, Bialkowska A, Bielecki S, Turkiewicz M, Cieslinski H, Kur J

Biocatal Biotransform. 2005

Cloning and preliminary characterization of a GATC-specific beta2-class DNA:m6A methyltransferase encoded by transposon Tn1549 from Enterococcus spp.

Radlińska M, Piekarowicz A, Galimand M, Bujnicki JM

Pol J Microbiol. 2005

Identification of amino acids important for target recognition by the DNA:m5C methyltransferase M.NgoPII by alanine-scanning mutagenesis of residues at the protein-DNA interface.

Radlinska M, Kondrzycka-Dada A, Piekarowicz A, Bujnicki JM

Proteins. 2005

Characterization of new DsbB-like thiol-oxidoreductases of Campylobacter jejuni and Helicobacter pylori and classification of the DsbB family based on phylogenomic, structural and functional criteria.

Raczko AM, Bujnicki JM, Pawlowski M, Godlewska R, Lewandowska M, Jagusztyn-Krynicka EK

Microbiology. 2005

Sequence-structure-function relationships of a tRNA (m7G46) methyltransferase studied by homology modeling and site-directed mutagenesis.

Purta E, van Vliet F, Tricot C, De Bie LG, Feder M, Skowronek K, Droogmans L, Bujnicki JM

Proteins. 2005

Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA.

Purushothaman SK, Bujnicki JM, Grosjean H, Lapeyre B

Mol Cell Biol. 2005

Specificity changes in the evolution of type II restriction endonucleases: a biochemical and bioinformatic analysis of restriction enzymes that recognize unrelated sequences

Pingoud V, Sudina A, Geyer H, Bujnicki JM, Lurz R, Lüder G, Morgan R, Kubareva E, Pingoud A

J Biol Chem. 2005

Identification of base-specific contacts in protein-DNA complexes by photocrosslinking and mass spectrometry: a case study using the restriction endonuclease SsoII

Pingoud V, Geyer H, Geyer R, Kubareva E, Bujnicki JM, Pingoud A

Mol Biosyst. 2005

Inference of relationships in the 'twilight zone' of homology using a combination of bioinformatics and site-directed mutagenesis: a case study of restriction endonucleases Bsp6I and PvuII

Pawlak SD, Radlinska M, Chmiel AA, Bujnicki JM, Skowronek KJ

Nucleic Acids Res. 2005

Analysis of the quaternary structure of the MutL C-terminal domain.

Kosinski J, Steindorf I, Bujnicki JM, Giron-Monzon L, Friedhoff P

J Mol Biol. 2005

The PD-(D/E)XK superfamily revisited: identification of new members among proteins involved in DNA metabolism and functional predictions for domains of (hitherto) unknown function.

Kosinski J, Feder M, Bujnicki JM

BMC Bioinformatics. 2005

Generalized protein structure prediction based on combination of fold-recognition with de novo folding and evaluation of models.

Koliński A, Bujnicki JM

Proteins. 2005

Discovery of a novel restriction endonuclease by genome comparison and application of a wheat-germ-based cell-free translation assay: PabI (5'-GTA/C) from the hyperthermophilic archaeon Pyrococcus abyssi

Ishikawa K, Watanabe M, Kuroita T, Uchiyama I, Bujnicki JM, Kawakami B, Tanokura M, Kobayashi I

Nucleic Acids Res. 2005

Identification of a new family of putative PD-(D/E)XK nucleases with unusual phylogenomic distribution and a new type of the active site.

Feder M, Bujnicki JM

BMC Genomics. 2005

DNase II is a member of the phospholipase D superfamily.

Cymerman IA, Meiss G, Bujnicki JM

Bioinformatics. 2005

A theoretical model of restriction endonuclease NlaIV in complex with DNA, predicted by fold recognition and validated by site-directed mutagenesis and circular dichroism spectroscopy.

Chmiel AA, Radlinska M, Pawlak SD, Krowarsch D, Bujnicki JM, Skowronek KJ

Protein Eng Des Sel. 2005

A homology model of restriction endonuclease SfiI in complex with DNA

Chmiel AA, Bujnicki JM, Skowronek KJ

BMC Struct Biol. 2005

Protein structure prediction: Boltzmann and Darwin (in Polish)

Bujnicki J.M.

Kosmos. 2005

Mva1269I: a monomeric type IIS restriction endonuclease from Micrococcus varians with two EcoRI- and FokI-like catalytic domains.

Armalyte E, Bujnicki JM, Giedriene J, Gasiunas G, Kosiński J, Lubys A

J Biol Chem. 2005

Mutational analysis of BTAF1-TBP interaction: BTAF1 can rescue DNA-binding defective TBP mutants.

Klejman MP, Zhao X, van Schaik FM, Herr W, Timmers HT

Nucleic Acids Res. 2005

Psc3 cohesin of Schizosaccharomyces pombe: cell cycle analysis and identification of three distinct isoforms.

Ilyushik E, Pryce DW, Walerych D, Riddell T, Wakeman JA, McInerny CJ, McFarlane RJ

Biol Chem. 2005

Characterization of testis-specific serine-threonine kinase 3 and its activation by phosphoinositide-dependent kinase-1-dependent signalling.

Bucko-Justyna M, Lipinski L, Burgering BM, Trzeciak L

FEBS J. 2005

2004

Primary ciliary dyskinesia: genes, candidate genes and chromosomal regions

Geremek M, Witt M

J Appl Genet. 2004

Apparent X-linked primary ciliary dyskinesia associated with retinitis pigmentosa and a hearing loss

Krawczyński MR, Dmeńska H, Witt M

J Appl Genet. 2004

PCD and RP: X-linked inheritance of both disorders?

Krawczyński MR, Witt M

Pediatr Pulmonol. 2004

Micronuclei in human cells – formation, contents, diagnostic and prognostic application

Lubka M, Wojda A, Witt M

Postępy Biol Kom. 2004

Kidney function estimated with different formulas in centenarians

Wieczorowska-Tobis K, Niemir ZI, Guzik P, Mossakowska M

Rocz Akad Med Bialymst. 2004

Blood pressure in centenarians in Poland

Zyczkowska J, Klich-Raczka A, Mossakowska M, Gasowski J, Wieczorowska-Tobis K, Grodzicki T

J Hum Hypertens. 2004

A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface

Filipek S, Krzysko KA , Fotiadis D, Liang Y, Saperstein DA, Engel A, Palczewski K

Photochem Photobiol Sci. 2004

The G protein-coupled receptor rhodopsin in the native membrane

Fotiadis D, Liang Y, Filipek S, Saperstein DA, Engel A, Palczewski K

FEBS Lett. 2004

Diversity of guanylate cyclase-activating proteins (GCAPs) in teleost fish: characterization of three novel GCAPs (GCAP4, GCAP5, GCAP7) from zebrafish (Danio rerio) and prediction of eight GCAPs (GCAP1-8) in pufferfish (

Imanishi Y, Yang L, Sokal I, Filipek S, Palczewski K, Baehr W

J Mol Evol. 2004

Functional characterization of rhodopsin monomers and dimers in detergents

Jastrzebska B, Maeda T, Zhu L, Fotiadis D, Filipek S, Engel A, Stenkamp RE, Palczewski K

J Biol Chem. 2004

Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice

Liang Y, Fotiadis D, Maeda T, Maeda A, Modzelewska A, Filipek S, Saperstein DA, Engel A, Palczewski K

J Biol Chem. 2004

Oligomerization of G protein-coupled receptors: past, present, and future.

Park PS, Filipek S, Wells JW, Palczewski K

Biochemistry. 2004

The supramolecular structure of the GPCR rhodopsin in solution and native disc membranes.

Suda K, Filipek S, Palczewski K, Engel A, Fotiadis D

Mol Membr Biol. 2004

A naturally occurring mutation of the opsin gene (T4R) in dogs affects glycosylation and stability of the G protein-coupled receptor.

Zhu L, Jang GF, Jastrzebska B, Filipek S, Pearce-Kelling SE, Aguirre GD, Stenkamp RE, Acland GM, Palczewski K

J Biol Chem. 2004

Calretinin gene promoter activity is differently regulated in neurons and cancer cells. Role of AP2-like cis element and zinc ions

Billing-Marczak K, Ziemińska E, Leśniak W, Łazarewicz JW, Kuźnicki J

Biochim Biophys Acta. 2004

Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain.

Lee YT, Jacob J, Michowski W, Nowotny M, Kuznicki J, Chazin WJ.

J Biol Chem.. 2004

Gene therapy of hematopoietic cells: development of strategies and vectors. (in Polish)

Wojda U.

Postepy Biol Kom. 2004

The E318G substitution in PSEN1 gene is not connected with Alzheimer's disease in a large Polish cohort.

Zekanowski C, Pepłońska B, Styczyńska M, Religa D, Pfeffer A, Czyzewski K, Gabryelewicz T, Szybińska A, Kijanowska-Haładyna B, Kotapka-Minc S, Łuczywek E, Barczak A, Wasiak B, Chodakowska-Zebrowska M, Przekop I, Kuźnicki J, Barcikowska M

Neurosci Lett. 2004

Genetic aspects of Alzheimer's disease

Zekanowski C, Religa D, Graff C, Filipek S, Kuźnicki J

Acta Neurobiol Exp (Wars). 2004

Proliferation and apoptosis of human CD8(+)CD28(+) and CD8(+)CD28(-) lymphocytes during aging

Brzezińska A, Magalska A, Szybińska A, Sikora E

Exp Gerontol. 2004

Peptidoglycan amidase MepA is a LAS metallopeptidase.

Marcyjaniak M, Odintsov SG, Sabala I, Bochtler M

J Biol Chem. 2004

Similar active sites in lysostaphins and D-Ala-D-Ala metallopeptidases.

Bochtler M, Odintsov SG, Marcyjaniak M, Sabala I

Protein Sci. 2004

Prostaphopain B structure: a comparison of proregion-mediated and staphostatin-mediated protease inhibition

Filipek R, Szczepanowski R, Sabat A, Potempa J, Bochtler M

Biochemistry. 2004

Peptidoglycan amidase MepA is a LAS metallopeptidase

Marcyjaniak M, Odintsov SG, Sabala I, Bochtler M

J Biol Chem. 2004

Latent LytM at 1.3A resolution

Odintsov SG, Sabala I, Marcyjaniak M, Bochtler M

J Mol Biol. 2004

Genetic characterization of staphopain genes in Staphylococcus aureus

Golonka E, Filipek R, Sabat A, Sinczak A, Potempa J

Biol Chem. 2004

Probabilistic cross-link analysis and experiment planning for high-throughput elucidation of protein structure.

Ye X, O\'Neil PK, Foster AN, Gajda MJ, Kosinski J, Kurowski MA, Bujnicki JM, Friedman AM, Bailey-Kellogg C

Protein Sci. 2004

Structural and functional characterization of mitochondrial EndoG, a sugar non-specific nuclease which plays an important role during apoptosis.

Schäfer P, Scholz SR, Gimadutdinow O, Cymerman IA, Bujnicki JM, Ruiz-Carrillo A, Pingoud A, Meiss G

J Mol Biol. 2004

COLORADO3D, a web server for the visual analysis of protein structures.

Sasin JM, Bujnicki JM

Nucleic Acids Res. 2004

Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily.

Saravanan M, Bujnicki JM, Cymerman IA, Rao DN, Nagaraja V

Nucleic Acids Res. 2004

A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase

Roovers M, Wouters J, Bujnicki JM, Tricot C, Stalon V, Grosjean H, Droogmans L

Nucleic Acids Res. 2004

Geometric analysis of cross-linkability for protein fold discrimination.

Potluri S, Khan AA, Kuzminykh A, Bujnicki JM, Friedman AM, Bailey-Kellogg C

Pac Symp Biocomput. 2004

Cooperative binding of the hnRNP K three KH domains to mRNA targets.

Paziewska A, Wyrwicz LS, Bujnicki JM, Bomsztyk K, Ostrowski J

FEBS Lett. 2004

Sterol methyltransferase: functional analysis of highly conserved residues by site-directed mutagenesis.

Nes WD, Jayasimha P, Zhou W, Kanagasabai R, Jin C, Jaradat TT, Shaw RW, Bujnicki JM

Biochemistry. 2004

Mutational analysis of basic residues in the N-terminus of the rRNA:m6A methyltransferase ErmC'

Maravić G, Bujnicki JM, Flögel M

Folia Microbiol (Praha). 2004

Homology modeling of the CG-specific DNA methyltransferase SssI and its complexes with DNA and AdoHcy.

Koudan EV, Bujnicki JM, Gromova ES

J Biomol Struct Dyn. 2004

Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA.

Bujnicki JM, Oudjama Y, Roovers M, Owczarek S, Caillet J, Droogmans L

RNA. 2004

Sequence-structure-function studies of tRNA:m5C methyltransferase Trm4p and its relationship to DNA:m5C and RNA:m5U methyltransferases.

Bujnicki JM, Feder M, Ayres CL, Redman KL

Nucleic Acids Res. 2004

N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.

Armengaud J, Urbonavicius J, Fernandez B, Chaussinand G, Bujnicki JM, Grosjean H

J Biol Chem. 2004

Homology modeling of the CG-specific DNA methyltransferase SssI and its complexes with DNA and AdoHcy.

Koudan EV, Bujnicki JM, Gromova ES

J Biomol Struct Dyn. 2004

Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA.

Bujnicki JM, Oudjama Y, Roovers M, Owczarek S, Caillet J, Droogmans L

RNA. 2004

Sequence-structure-function studies of tRNA:m5C methyltransferase Trm4p and its relationship to DNA:m5C and RNA:m5U methyltransferases.

Bujnicki JM, Feder M, Ayres CL, Redman KL

Nucleic Acids Res. 2004

N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota.

Armengaud J, Urbonavicius J, Fernandez B, Chaussinand G, Bujnicki JM, Grosjean H

J Biol Chem. 2004

Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II.

Mycko MP, Cwiklinska H, Szymanski J, Szymanska B, Kudla G, Kilianek L, Odyniec A, Brosnan CF, Selmaj KW

J Immunol. 2004

Hsp90 chaperones wild-type p53 tumor suppressor protein.

Walerych D, Kudla G, Gutkowska M, Wawrzynow B, Muller L, King FW, Helwak A, Boros J, Zylicz A, Zylicz M

J Biol Chem. 2004

P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma.

Jassem J, Jassem E, Jakóbkiewicz-Banecka J, Rzyman W, Badzio A, Dziadziuszko R, Kobierska-Gulida G, Szymanowska A, Skrzypski M, Zylicz M

Cancer. 2004

MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC).

Dworakowska D, Jassem E, Jassem J, Peters B, Dziadziuszko R, Zylicz M, Jakóbkiewicz-Banecka J, Kobierska-Gulida G, Szymanowska A, Skokowski J, Roessner A, Schneider-Stock R

Lung Cancer. 2004

Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II.

Mycko MP, Cwiklinska H, Szymanski J, Szymanska B, Kudla G, Kilianek L, Odyniec A, Brosnan CF, Selmaj KW

J Immunol. 2004

Gene conversion and GC-content evolution in mammalian Hsp70.

Kudla G, Helwak A, Lipinski L

Mol Biol Evol. 2004

Hsp90 chaperones wild-type p53 tumor suppressor protein.

Walerych D, Kudla G, Gutkowska M, Wawrzynow B, Muller L, King FW, Helwak A, Boros J, Zylicz A, Zylicz M

J Biol Chem. 2004

Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures.

Müller L, Schaupp A, Walerych D, Wegele H, Buchner J

J Biol Chem. 2004

P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma.

Jassem J, Jassem E, Jakóbkiewicz-Banecka J, Rzyman W, Badzio A, Dziadziuszko R, Kobierska-Gulida G, Szymanowska A, Skrzypski M, Zylicz M

Cancer. 2004

MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC).

Dworakowska D, Jassem E, Jassem J, Peters B, Dziadziuszko R, Zylicz M, Jakóbkiewicz-Banecka J, Kobierska-Gulida G, Szymanowska A, Skokowski J, Roessner A, Schneider-Stock R

Lung Cancer. 2004

2003

Functioning of Polish centenarians

Pruszynski J, Gross R, Mossakowska M, Barcikowska M, Czyzewski K, Derejczyk J, Galus K, Grodzicki T, Jedrkiewicz H, Klich-Raczka A, Kupsc W, Luczywek E, Pfeffer A, Puzianowska-Kuznicka M, Sosnowski M, Styczynska M, Wasiak B, Wieczorowska-Tobis K, Zyczkows

Gerontologia. 2003

Manifestations of ageing at the cytogenetic level

Wojda A, Witt M

J Appl Genet. 2003

The 102-year old woman with translocation (7;12) and infertility in anamnesis

Wojda A, Wolnik-Brzozowska D, Lubka M, Mossakowska M, Witt M

J Appl Genet. 2003

Hypertension and cognitive and functional performance in centenarians

Zyczkowska J, Klich-Raczka A, Wizner B, Mossakowska M, Wieczorowska-Tobis K, Grodzicki T

New Medicine. 2003

Cystic fibrosis--a probable cause of Frédéric Chopin's suffering and death

Majka L, Goździk J, Witt M

J Appl Genet. 2003

The crystallographic model of rhodopsin and its use in studies of other G protein-coupled receptors.

Filipek S, Teller DC, Palczewski K, Stenkamp R

Annu Rev Biophys Biomol Struct. 2003

Atomic-force microscopy: Rhodopsin dimers in native disc membranes

Fotiadis D, Liang Y, Filipek S, Saperstein DA, Engel A, Palczewski K

Nature. 2003

Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation.

Fritze O, Filipek S, Kuksa V, Palczewski K, Hofmann KP, Ernst OP

Proc Natl Acad Sci U S A. 2003

Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes.

Liang Y, Fotiadis D, Filipek S, Saperstein DA, Palczewski K, Engel A

J Biol Chem. 2003

Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes

Liang Y, Fotiadis D, Filipek S, Saperstein DA, Palczewski K, Engel A

J Biol Chem. 2003

Evaluation of the role of the retinal G protein-coupled receptor (RGR) in the vertebrate retina in vivo.

Maeda T, Van Hooser JP, Driessen CA, Filipek S, Janssen JJ, Palczewski K

J Neurochem. 2003

Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin.

Mirzadegan T, Benkö G, Filipek S, Palczewski K

Biochemistry. 2003

Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosa.

Noorwez SM, Kuksa V, Imanishi Y, Zhu L, Filipek S, Palczewski K, Kaushal S

J Biol Chem. 2003

Ligand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin.

Schadel SA, Heck M, Maretzki D, Filipek S, Teller DC, Palczewski K, Hofmann KP

J Biol Chem. 2003

Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins

Nowotny M, Spiechowicz M, Jastrzebska B, Filipek A, Kitagawa K, Kuznicki J

J Biol Chem. 2003

Calretinin and calbindin D28k have different domain organizations

Palczewska M, Groves P, Batta G, Heise B, Kuźnicki J

Protein Sci. 2003

Strong association between Saitohin gene polymorphism and tau haplotype in the Polish population

Pepłońska B, Zekanowski C, Religa D, Czyzewski K, Styczyńska M, Pfeffer A, Gabryelewicz T, Gołebiowski M, Luczywek E, Wasiak B, Barczak A, Chodakowska M, Barcikowska M, Kuźnicki J

Neurosci Lett. 2003

Mutations in presenilin 1, presenilin 2 and amyloid precursor protein genes in patients with early-onset Alzheimer's disease in Poland

Zekanowski C, Styczyńska M, Pepłońska B, Gabryelewicz T, Religa D, Ilkowski J, Kijanowska-Haładyna B, Kotapka-Minc S, Mikkelsen S, Pfeffer A, Barczak A, Łuczywek E, Wasiak B, Chodakowska-Zebrowska M, Gustaw K, Łaczkowski J, Sobów T, Kuźnicki J, Barcikowsk

Exp Neurol. 2003

Mutation screening of the MAPT and STH genes in Polish patients with clinically diagnosed frontotemporal dementia

Zekanowski C, Pepłońska B, Styczyńska M, Gustaw K, Kuźnicki J, Barcikowska M

Dement Geriatr Cogn Disord. 2003

Alzheimer's disease: between diagnostic, economy and ethic (in Polish)

Zekanowski C, Przyluska-Fiszer A, Barcikowska M

Choroby otępienne. Teoria i praktyka. 2003

Genetic diversity within the R408W phenylketonuria mutation lineages in Europe

Tighe O, Dunican D, O'Neill C, Bertorelle G, Beattie D, Graham C, Zschocke J, Cali F, Romano V, Hrabincova E, Kozak L, Nechyporenko M, Livshits L, Guldberg P, Jurkowska M, Zekanowski C, Perez B, Desviat LR, Ugarte M, Kucinskas V, Knappskog P, Treacy E, N

Hum Mutat. 2003

The sun, the genome, the internet… eugenics?

Zekanowski C

Gemellological Rev. 2003

Molecular diagnostics of Alzheimer's disease (in Polish)

Zekanowski C

Medycyna ogólna. 2003

A novel class of cysteine protease inhibitors: solution structure of staphostatin A from Staphylococcus aureus.

Dubin G, Krajewski M, Popowicz G, Stec-Niemczyk J, Bochtler M, Potempa J, Dubin A, Holak TA

Biochemistry. 2003

The Staphostatin-staphopain complex: a forward binding inhibitor in complex with its target cysteine protease.

Filipek R, Rzychon M, Oleksy A, Gruca M, Dubin A, Potempa J, Bochtler M

J Biol Chem. 2003

Staphostatins resemble lipocalins, not cystatins in fold

Rzychon M, Filipek R, Sabat A, Kosowska K, Dubin A, Potempa J, Bochtler M

Protein Sci. 2003

Experimental evidence for a beta beta alpha-Me-finger nuclease motif to represent the active site of the caspase-activated DNase.

Scholz SR, Korn C, Bujnicki JM, Gimadutdinow O, Pingoud A, Meiss G

Biochemistry. 2003

STRUCLA: a WWW meta-server for protein structure comparison and evolutionary classification.

Sasin JM, Kurowski MA, Bujnicki JM

Bioinformatics. 2003

PspGI, a type II restriction endonuclease from the extreme thermophile Pyrococcus sp.: structural and functional studies to investigate an evolutionary relationship with several mesophilic restriction enzymes

Pingoud V, Conzelmann C, Kinzebach S, Sudina A, Metelev V, Kubareva E, Bujnicki JM, Lurz R, Lüder G, Xu SY, Pingoud A

J Mol Biol. 2003

Sequence-structure-function relationships of Tgs1, the yeast snRNA/snoRNA cap hypermethylase

Mouaikel J, Bujnicki JM, Tazi J, Bordonné R

Nucleic Acids Res. 2003

Mutational analysis defines the roles of conserved amino acid residues in the predicted catalytic pocket of the rRNA:m6A methyltransferase ErmC'

Maravić G, Feder M, Pongor S, Flögel M, Bujnicki JM

J Mol Biol. 2003

Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions

Maravić G, Bujnicki JM, Feder M, Pongor S, Flögel M

Nucleic Acids Res. 2003

Characterization of the cofactor-binding site in the SPOUT-fold methyltransferases by computational docking of S-adenosylmethionine to three crystal structures.

Kurowski MA, Sasin JM, Feder M, Debski J, Bujnicki JM

BMC Bioinformatics. 2003

GeneSilico protein structure prediction meta-server.

Kurowski MA, Bujnicki JM

Nucleic Acids Res. 2003

Phylogenomic identification of five new human homologs of the DNA repair enzyme AlkB.

Kurowski MA, Bhagwat AS, Papaj G, Bujnicki JM

BMC Genomics. 2003

A "FRankenstein's monster" approach to comparative modeling: merging the finest fragments of Fold-Recognition models and iterative model refinement aided by 3D structure evaluation

Kosinski J, Cymerman IA, Feder M, Kurowski MA, Sasin JM, Bujnicki JM

Proteins. 2003

Anti-HIV-1 activity of 3-deaza-adenosine analogs. Inhibition of S-adenosylhomocysteine hydrolase and nucleotide congeners.

Gordon RK, Ginalski K, Rudnicki WR, Rychlewski L, Pankaskie MC, Bujnicki JM, Chiang PK

Eur J Biochem. 2003

Molecular phylogenetics of the RrmJ/fibrillarin superfamily of ribose 2'-O-methyltransferases

Feder M, Pas J, Wyrwicz LS, Bujnicki JM

Gene. 2003

Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures.

Droogmans L, Roovers M, Bujnicki JM, Tricot C, Hartsch T, Stalon V, Grosjean H

Nucleic Acids Res. 2003

The yggH gene of Escherichia coli encodes a tRNA (m7G46) methyltransferase.

De Bie LG, Roovers M, Oudjama Y, Wattiez R, Tricot C, Stalon V, Droogmans L, Bujnicki JM

J Bacteriol. 2003

Structure, evolution, and inhibitor interaction of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.

Bujnicki JM, Prigge ST, Caridha D, Chiang PK

Proteins. 2003

Fold recognition, homology modeling, docking simulations, kinetics analysis and mutagenesis of ATP/CTP:tRNA nucleotidyltransferase from Methanococcus jannaschii.

Bujnicki JM, Albert MA, Nelson DJ, Thurlow DL

Proteins. 2003

Crystallographic and bioinformatic studies on restriction endonucleases: inference of evolutionary relationships in the "midnight zone" of homology

Bujnicki JM

Curr Protein Pept Sci. 2003

Biochemical characterization of a beta-galactosidase with a low temperature optimum obtained from an Antarctic arthrobacter isolate.

Coker JA, Sheridan PP, Loveland-Curtze J, Gutshall KR, Auman AJ, Brenchley JE

J Bacteriol. 2003

Biochemical characterization of a beta-galactosidase with a low temperature optimum obtained from an Antarctic arthrobacter isolate.

Coker JA, Sheridan PP, Loveland-Curtze J, Gutshall KR, Auman AJ, Brenchley JE

J Bacteriol. 2003

Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins

Nowotny M, Spiechowicz M, Jastrzebska B, Filipek A, Kitagawa K, Kuznicki J

J Biol Chem.. 2003

2002

Discrepancies in creatinine clearance in centenarians when calculated by two different mathematical formulas

Wieczorowska-Tobis K, Mossakowska M, Niemir Z, Breborowicz A, Oreopoulos DG

Nephrol Dial Transplant. 2002

Anemia in centenarians

Wieczorowska-Tobis K, Niemir Z, Mossakowska M, Klich-Raczka A, Zyczkowska J

J Am Geriatr Soc. 2002

Biochemical and physiological properties of rhodopsin regenerated with 11-cis-6-ring- and 7-ring-retinals.

Kuksa V, Bartl F, Maeda T, Jang GF, Ritter E, Heck M, Van Hooser JP, Liang Y, Filipek S, Gelb MH, Hofmann KP, Palczewski K

J Biol Chem. 2002

AP2-like cis element is required for calretinin gene promoter activity in cells of neuronal phenotype differentiated from multipotent human cell line DEV

Billing-Marczak K, Buzanska L, Winsky L, Nowotny M, Rudka T, Isaacs K, Belin MF, Kuznicki J

Biochim Biophys Acta. 2002

CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family

Filipek A, Jastrzebska B, Nowotny M, Kuznicki J

J Biol Chem. 2002

Ca2+-dependent translocation of the calcyclin-binding protein in neurons and neuroblastoma NB-2a cells

Filipek A, Jastrzebska B, Nowotny M, Kwiatkowska K, Hetman M, Surmacz L, Wyroba E,Kuznicki J

J Biol Chem. 2002

Atypical PKU - treatment effectiveness

Cabalska B, Nowacka M, Nowaczewska I, Zekanowski C, Zorska K

Medycyna Wieku Rozwojowego VI. 2002

Novel PKU treatment methods

Zekanowski C, Gizewska M, Nowacka M, Cabalska B

Medycyna Wieku Rozwojowego. 2002

Genetic aspects of Alzheimer’s disease

Zekanowski C

Medycyna Ogólna. 2002

Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY)

Ramachandran R, Hartmann C, Song HK, Huber R, Bochtler M

Proc Natl Acad Sci U S A. 2002

Angiogenesis inhibitors specific for methionine aminopeptidase 2 as drugs for malaria and leishmaniasis

Zhang P, Nicholson DE, Bujnicki JM, Su X, Brendle JJ, Ferdig M, Kyle DE, Milhous WK, Chiang PK

J Biomed Sci. 2002

Streptococcal Scl1 and Scl2 proteins form collagen-like triple helices.

Xu Y, Keene DR, Bujnicki JM, Höök M, Lukomski S

J Biol Chem. 2002

Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop

Pintard L, Lecointe F, Bujnicki JM, Bonnerot C, Grosjean H, Lapeyre B

EMBO J. 2002

MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase

Pintard L, Bujnicki JM, Lapeyre B, Bonnerot C

EMBO J. 2002

Evolutionary relationship between different subgroups of restriction endonucleases.

Pingoud V, Kubareva E, Stengel G, Friedhoff P, Bujnicki JM, Urbanke C, Sudina A, Pingoud A

J Biol Chem. 2002

The hppA gene of Helicobacter pylori encodes the class C acid phosphatase precursor

Godlewska R, Bujnicki JM, Ostrowski J, Jagusztyn-Krynicka EK

FEBS Lett. 2002

Fold-recognition detects an error in the Protein Data Bank

Bujnicki J, Rychlewski L, Fischer D

Bioinformatics. 2002

In silico identification, structure prediction and phylogenetic analysis of the 2'-O-ribose (cap 1) methyltransferase domain in the large structural protein of ssRNA negative-strand viruses

Bujnicki JM, Rychlewski L

Protein Eng. 2002

RNA:(guanine-N2) methyltransferases RsmC/RsmD and their homologs revisited--bioinformatic analysis and prediction of the active site based on the uncharacterized Mj0882 protein structure

Bujnicki JM, Rychlewski L

BMC Bioinformatics. 2002

Fold-recognition analysis predicts that the Tag protein family shares a common domain with the helix-hairpin-helix DNA glycosylases

Bujnicki JM, Rychlewski L

DNA Repair (Amst). 2002

Bioinformatic analyses of the tRNA: (guanine 26, N2,N2)-dimethyltransferase (Trm1) family

Bujnicki JM, Leach RA, Debski J, Rychlewski L

J Mol Microbiol Biotechnol. 2002

Errors in the D. radiodurans large ribosomal subunit structure detected by protein fold-recognition and structure validation tools

Bujnicki JM, Feder M, Rychlewski L, Fischer D

FEBS Lett. 2002

Structure prediction and phylogenetic analysis of a functionally diverse family of proteins homologous to the MT-A70 subunit of the human mRNA:m(6)A methyltransferase

Bujnicki JM, Feder M, Radlinska M, Blumenthal RM

J Mol Evol. 2002

Sequence analysis and structure prediction of 23S rRNA:m1G methyltransferases reveals a conserved core augmented with a putative Zn-binding domain in the N-terminus and family-specific elaborations in the C-terminus

Bujnicki JM, Blumenthal RM, Rychlewski L

J Mol Microbiol Biotechnol. 2002

Sequence permutations in the molecular evolution of DNA methyltransferases

Bujnicki JM

BMC Evol Biol. 2002

Ca2+-dependent translocation of the calcyclin-binding protein in neurons and neuroblastoma NB-2a cells.

Filipek A, Jastrzebska B, Nowotny M, Kwiatkowska K, Hetman M, Surmacz L, Wyroba E, Kuznicki J

J Biol Chem. 2002

CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family

Filipek A, Jastrzebska B, Nowotny M, Kuznicki J

J Biol Chem. 2002

AP2-like cis element is required for calretinin gene promoter activity in cells of neuronal phenotype differentiated from multipotent human cell line DEV.

Billing-Marczak K, Buzanska L, Winsky L, Nowotny M, Rudka T, Isaacs K, Belin MF, Kuznicki J.

Biochim Biophys Acta. 2002

2001

Plasma creatine and sodium abnormalities in Polish centenarians

Wieczorowska-Tobis K, Mossakowska M, Niemir Z, Breborowicz A, Oreopoulos DG

Ann Acad Med Gedan. 2001

Structural and biochemical characterization of neuronal calretinin domain I-II (residues 1-100). Comparison to homologous calbindin D28k domain I-II (residues 1-93)

Palczewska M, Groves P, Ambrus A, Kaleta A, Kövér KE, Batta G, Kuźnicki J.

Eur J Biochem.. 2001

Site-directed mutagenesis defines the catalytic aspartate in the active site of the atypical DNA: m4C methyltransferase M.NgoMXV

Radlinska M, Bujnicki JM

Acta Microbiol Pol. 2001

Cloning of enterohemorrhagic Escherichia coli phage VT-2 dam methyltransferase

Radlinska M, Bujnicki JM

Acta Microbiol Pol. 2001

Pcons: a neural-network-based consensus predictor that improves fold recognition

Lundström J, Rychlewski L, Bujnicki J, Elofsson A

Protein Sci. 2001

The herpesvirus alkaline exonuclease belongs to the restriction endonuclease PD-(D/E)XK superfamily: insight from molecular modeling and phylogenetic analysis.

Bujnicki JM, Rychlewski L

Virus Genes. 2001

Grouping together highly diverged PD-(D/E)XK nucleases and identification of novel superfamily members using structure-guided alignment of sequence profiles.

Bujnicki JM, Rychlewski L

J Mol Microbiol Biotechnol. 2001

Reassignment of specificities of two cap methyltransferase domains in the reovirus lambda 2 protein

Bujnicki JM, Rychlewski L

Genome Biol. 2001

Unusual evolutionary history of the tRNA splicing endonuclease EndA: relationship to the LAGLIDADG and PD-(D/E)XK deoxyribonucleases.

Bujnicki JM, Rychlewski L

Protein Sci. 2001

Identification of a PD-(D/E)XK-like domain with a novel configuration of the endonuclease active site in the methyl-directed restriction enzyme Mrr and its homologs

Bujnicki JM, Rychlewski L

Gene. 2001

Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases

Bujnicki JM, Rychlewski L

Acta Microbiol Pol. 2001

Three-dimensional modeling of the I-TevI homing endonuclease catalytic domain, a GIY-YIG superfamily member, using NMR restraints and Monte Carlo dynamics.

Bujnicki JM, Rotkiewicz P, Kolinski A, Rychlewski L

Protein Eng. 2001

Cloning of the Haemophilus influenzae Dam methyltransferase and analysis of its relationship to the Dam methyltransferase encoded by the HP1 phage

Bujnicki JM, Radlinska M, Zaleski P, Piekarowicz A

Acta Biochim Pol. 2001

Polyphyletic evolution of type II restriction enzymes revisited: two independent sources of second-hand folds revealed

Bujnicki JM, Radlinska M, Rychlewski L

Trends Biochem Sci. 2001

Cloning and characterization of M.LmoA118I, a novel DNA:m4C methyltransferase from the Listeria monocytogenes phage A118, a close homolog of M.NgoMXV

Bujnicki JM, Radlinska M

Acta Microbiol Pol. 2001

mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships

Bujnicki JM, Feder M, Radlinska M, Rychlewski L

BMC Bioinformatics. 2001

LiveBench-2: large-scale automated evaluation of protein structure prediction servers.

Bujnicki JM, Elofsson A, Fischer D, Rychlewski L

Proteins. 2001

LiveBench-1: continuous benchmarking of protein structure prediction servers

Bujnicki JM, Elofsson A, Fischer D, Rychlewski L

Protein Sci. 2001

Structure prediction meta server

Bujnicki JM, Elofsson A, Fischer D, Rychlewski L

Bioinformatics. 2001

A model of structure and action of Sau3AI restriction endonuclease that comprises two MutH-like endonuclease domains within a single polypeptide.

Bujnicki JM

Acta Microbiol Pol. 2001

Understanding the evolution of restriction-modification systems: clues from sequence and structure comparisons.

Bujnicki JM

Acta Biochim Pol. 2001

In silico analysis of the tRNA:m1A58 methyltransferase family: homology-based fold prediction and identification of new members from Eubacteria and Archaea

Bujnicki JM

FEBS Lett. 2001

Multitemperature single-strand conformation polymorphism.

Kaczanowski R, Trzeciak L, Kucharczyk K

Electrophoresis. 2001

Insights into the function of Hsp70 chaperones.

Zylicz M, Wawrzynow A

IUBMB Life. 2001

Hsp70 interactions with the p53 tumour suppressor protein

Zylicz M, King FW, Wawrzynow A

EMBO J. 2001

Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.

King FW, Wawrzynow A, Höhfeld J, Zylicz M

EMBO J. 2001

Types and localisation of p53 gene mutations: a report on 332 non-small cell lung cancer patients.

Jassem E, Nikliński J, Rosell R, Niklińska W, Jakóbkiewicz J, Monzo M, Chyczewski L, Kobierska G, Skokowski J, Zylicz M, Jassem J

Lung Cancer. 2001

DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction.

Genevaux P, Wawrzynow A, Zylicz M, Georgopoulos C, Kelley WL

J Biol Chem. 2001

Structure-function analysis of the zinc-binding region of the Clpx molecular chaperone.

Banecki B, Wawrzynow A, Puzewicz J, Georgopoulos C, Zylicz M

J Biol Chem. 2001

Multitemperature single-strand conformation polymorphism.

Kaczanowski R, Trzeciak L, Kucharczyk K

Electrophoresis. 2001

Insights into the function of Hsp70 chaperones.

Zylicz M, Wawrzynow A

IUBMB Life. 2001

Hsp70 interactions with the p53 tumour suppressor protein

Zylicz M, King FW, Wawrzynow A

EMBO J. 2001

Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.

King FW, Wawrzynow A, Höhfeld J, Zylicz M

EMBO J. 2001

DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction.

Genevaux P, Wawrzynow A, Zylicz M, Georgopoulos C, Kelley WL

J Biol Chem. 2001

Structure-function analysis of the zinc-binding region of the Clpx molecular chaperone.

Banecki B, Wawrzynow A, Puzewicz J, Georgopoulos C, Zylicz M

J Biol Chem. 2001

2000

Characterization of the interaction of calcyclin (S100A6) and calcyclin-binding protein.

Nowotny M, Bhattacharya S, Filipek A, Krezel AM, Chazin W, Kuznicki J.

J Biol Chem.. 2000

Calcyclin (S100A6) binding protein (CacyBP) is highly expressed in brain neurons.

Jastrzebska B, Filipek A, Nowicka D, Kaczmarek L, Kuznicki J.

J Histochem Cytochem.. 2000

Upstream stimulatory factor is involved in the regulation of the human calcyclin (S100A6) gene.

Leśniak W, Jezierska A, Kuźnicki J.

Biochim Biophys Acta.. 2000

Regulation of cell specific expression of calcyclin (S100A6) in nerve cells and other tissues.

Leśniak W, Swart GW, Bloemers HP, Kuźnicki J.

Acta Neurobiol Exp (Wars). . 2000

Cloning - the crossroads of biology and culture

Zekanowski C

Gemellological Review. 2000

Polish Centenarians Program “PolStu99” – search for longevity promoting factors (in Polish)

Mossakowska M, Puzianowska-Kuznicka M, Barcikowska M, Chiron-Jouan S, Czyzewski K, Derejczyk J, Franceschi C, Gabryelewicz T, Galus K, Grodzicki T, Gross R, Klich-Raczka A, Luczywek E, Passeri G, Pfeffer A, Pruszynski J, Radziszewska E, Sikora E, Sosnowski M, Styczynska M, Wasiak B, Wieczorowska-Tobis K, Zyczkowska J, Kuznicki J

Gerontologia. 2000

Prediction of a common fold for all four subunits of the yeast tRNA splicing endonuclease: implications for the evolution of the EndA/Sen family.

Bujnicki JM, Rychlewski L

FEBS Lett. 2000

Prediction of a novel RNA 2'-O-ribose methyltransferase subfamily encoded by the Escherichia coli YgdE open reading frame and its orthologs

Bujnicki JM, Rychlewski L

Acta Microbiol Pol. 2000

Atomic model of the 5-methylcytosine-specific restriction enzyme McrA reveals an atypical zinc finger and structural similarity to betabetaalphaMe endonucleases

Bujnicki JM, Radlinska M, Rychlewski L

Mol Microbiol. 2000

Sequence, structural, and evolutionary analysis of prokaryotic ribosomal protein L11 methyltransferases.

Bujnicki JM

Acta Microbiol Pol. 2000

Phylogenomic analysis of 16S rRNA:(guanine-N2) methyltransferases suggests new family members and reveals highly conserved motifs and a domain structure similar to other nucleic acid amino-methyltransferases.

Bujnicki JM

FASEB J. 2000