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Laboratorium Metabolizmu Białek

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2022

Piechota M, Biriczova L, Kowalski K, Szulc NA, Pokrzywa W.

CHIP ubiquitin ligase is involved in the nucleolar stress management.

Szulc NA, Stefaniak F, Piechota M, Cappannini A, Bujnicki JM, Pokrzywa W.

DEGRONOPEDIA - a web server for proteome-wide inspection of degrons.

Slusarczyk P, Mandal PK, Zurawska G, Niklewicz M, Chouhan KK, Macias M, Szybinska A, Cybulska M, Krawczyk O, Herman S, Mikula M, Serwa R, Lenartowicz M, Pokrzywa W, Mleczko-Sanecka K.

Impaired iron recycling from erythrocytes is an early hallmark of aging.

Dubey AA, Krygier M, Szulc NA, Rutkowska K, Kosinska J, Pollak A, Rydzanicz M, Kmiec T, Mazurkiewicz-Beldzinska M, Pokrzywa W, Ploski R.

A novel de novo FEM1C variant as a potential cause of neurodevelopmental disorder with absent speech, pyramidal signs, and limb ataxia.

2021

Banasiak K, Szulc NA, Pokrzywa W.

The Dose-Dependent Pleiotropic Effects of the UBB+1 Ubiquitin Mutant.

Turek M, Banasiak K, Piechota M, Shanmugam N, Macias M, Śliwińska MA, Niklewicz M, Kowalski K, Nowak N, Chacinska A, Pokrzywa W.

Muscle-derived exophers promote reproductive fitness.

Das A, Thapa P, Santiago U, Shanmugam N, Banasiak K, Dabrowska K, Nolte H, Szulc NA, Gathungu RM, Cysewski D, Krüger M, Dadlez M, Nowotny M, Camacho CJ, Hoppe T, Pokrzywa W.

Heterotypic Assembly Mechanism Regulates CHIP E3 Ligase Activity.

Höhfeld J, Benzing T, Bloch W, Fürst DO, Gehlert S, Hesse M, Hoffmann B, Hoppe T, Huesgen PF, Köhn M, Kolanus W, Merkel R, Niessen CM, Pokrzywa W, Rinschen MM, Wachten D, Warscheid B.

Maintaining proteostasis under mechanical stress.

2020

Thapa P, Shanmugam N, Pokrzywa W.

Ubiquitin Signaling Regulates RNA Biogenesis, Processing, and Metabolism.

Macnar JM, Szulc N, Kryś JD, Badaczewska-Dawid AE, Gront D.

Article BioShell 3.0: Library for Processing Structural Biology Data.

Fatima A, Irmak D, Noormohammadi A, Rinschen MM, Das A, Leidecker O, Schindler C, Sánchez-Gaya V, Wagle P, Pokrzywa W, Hoppe T, Rada-Iglesias A, Vilchez D.

The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells.

Turek M, Piechota M, Shanmugam N, Niklewicz M, Kowalski K, Chacińska A, Pokrzywa W.

Nutritional status and fecundity are synchronised by muscular exopheresis.

Albert M-C, Brinkmann K, Pokrzywa W, Günther SD, Krönke M, Hoppe T, Kashkar H.

CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage.

2018

Koyuncu S, Saez I, Lee HJ, Gutierrez-Garcia R, Pokrzywa W, Fatima A, Hoppe T, Vilchez D.

The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients.

Balaji V, Pokrzywa W, Hoppe T.

Ubiquitylation Pathways In Insulin Signaling and Organismal Homeostasis.

2017

Kevei É, Pokrzywa W, Hoppe T

Repair or Destruction: An Intimate Liaison Between Ubiquitin Ligases and Molecular Chaperones in Proteostasis

Pokrzywa W, Lorenz R, Hoppe T

Chaperone-directed ubiquitylation maintains proteostasis at the expense of longevity.

Pokrzywa W, Hoppe T.

CHIPped balance of proteostasis and longevity.