GRIEG: W. Pokrzywa
Dr. Wojciech Pokrzywa has received funding under the GRIEG call for research projects financed from the Norwegian Financial Mechanism 2014 – 2021 to conduct research under the project: Cellular adaptation to cold.

Cellular adaptation to cold (CellCOLD)
GRIEG project no.: 2019/34/H/NZ3/00691
prof. Rafał Ciosk, University of Oslo
project promoter:
International Institute of Molecular and Cell Biology in Warsaw
project investigator:
Wojciech Pokrzywa, PhD
granted funds:
6 389 842 PLN / 1 499 998 EUR
Last news
Project aim & description
Cellular adaptation to cold

Environmental stressors can seriously jeopardize animals’ ability to survive and reproduce. One, potentially dangerous, environmental stressor is acute cold. To counteract cold, affected organisms mount various types of responses, ranging from cold avoidance to adaptation. The latter strategy is used by hibernating animals, which, in extreme cases, can survive subzero temperatures for many days. Here, we propose to utilize a simple animal model, the nematode Caenorhabditis elegans, as a rapid tool to understand cellular adaptations to cold. We will focus on mechanisms altering the abundance and types of cellular messenger RNAs and proteins, as these kinds of molecules are critical for the live-or-die decision of the cell. In some disease states, like stroke, cooling can facilitate patient’s recovery. Moreover, hibernation is of interest to ageing research, as animals tend to live longer at lower temperatures. Thus, understanding how cells adapt to cold has the potential to influence treatments of human disorders.

The purpose of our project
prof. Wojciech Pokrzywa
Wojciech Pokrzywa, PhD - International Institute of Molecular and Cell Biology in Warsaw

Prof. Rafał Ciosk
University of Oslo

Contact in
scientific matters:
Project management:
Agata Skaruz,
Project PR and Communication: