2012

Crystal structure and mechanism of action of the N6-methyladenine dependent type IIM restriction endonuclease Siwek W, Czapinska H, Bochtler M, Bujnicki JM, Skowronek K Nucleic Acids Res. 2012 RIBER/DIBER: a software suite for crystal content analysis in the studies of protein-nucleic acid complexes Chojnowski G, Bujnicki JM, Bochtler M Bioinformatics. 2012

2011

Importance of single molecular determinants in the fidelity of expanded genetic codes Antonczak AK, Simova Z, Yonemoto IT, Bochtler M, Piasecka A, Czapinska H, Brancale A, Tippmann EM Proc Natl Acad Sci U S A.. 2011 Amyloid-associated nucleic acid hybridisation Braun S, Humphreys C, Fraser E, Brancale A, Bochtler M, Dale TC PLoS One. 2011 DNA intercalation without flipping in the specific ThaI-DNA complex Firczuk M, Wojciechowski M, Czapinska H, Bochtler M Nucleic Acids Res. 2011 Hpy188I-DNA pre- and post-cleavage complexes--snapshots of the GIY-YIG nuclease mediated catalysis Sokolowska M, Czapinska H, Bochtler M Nucleic Acids Res. 2011

2010

DIBER: protein, DNA or both? Chojnowski G, Bochtler M Acta Crystallogr D Biol Crystallogr. 2010 Alu-repeat-induced deletions within the NCF2 gene causing p67-phox-deficient chronic granulomatous disease (CGD) Gentsch M, Kaczmarczyk A, van Leeuwen K, de Boer M, Kaus-Drobek M, Dagher MC, Kaiser P, Arkwright PD, Gahr M, Rösen-Wolff A, Bochtler M, Secord E, Britto-Williams P, Saifi GM, Maddalena A, Dbaibo G, Bustamante J, Casanova JL, Roos D, Roesler J Hum Mutat. 2010 1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state Chojnowski G, Breer K, Narczyk M, Wielgus-Kutrowska B, Czapinska H, Hashimoto M, Hikishima S, Yokomatsu T, Bochtler M, Girstun A, Staroń K, Bzowska A Biochem Biophys Res Commun. 2010 Crystallization of the Photosystem II core complex and its chlorophyll binding subunit CP43 from transplastomic plants of Nicotiana tabacum Piano D, El Alaoui S, Korza HJ, Filipek R, Sabala I, Haniewicz P, Buechel C, De Sanctis D, Bochtler M Photosynth Res. 2010

2009

Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA Sokolowska M, Czapinska H, Bochtler M Nucleic Acids Res. 2009

2008

Central base pair flipping and discrimination by PspGI Szczepanowski RH, Carpenter MA, Czapinska H, Zaremba M, Tamulaitis G, Siksnys V, Bhagwat AS, Bochtler M Nucleic Acids Res. 2008 How PspGI, catalytic domain of EcoRII and Ecl18kI acquire specificities for different DNA targets Tamulaitis G, Zaremba M, Szczepanowski RH, Bochtler M, Siksnys V Nucleic Acids Res. 2008 Thermodynamic studies of interactions of calf spleen PNP with acyclic phosphonate inhibitors Breer K, Wielgus-Kutrowska B, Hashimoto M, Hikishima S, Yokomatsu T, Szczepanowski RH, Bochtler M, Girstun A, Starón K, Bzowska A Nucleic Acids Symp Ser (Oxf). 2008 The recognition domain of the BpuJI restriction endonuclease in complex with cognate DNA at 1.3-A resolution Sukackaite R, Grazulis S, Bochtler M, Siksnys V. J Mol Biol. 2008 Crystal structure and mechanism of the Staphylococcus cohnii virginiamycin B lyase (Vgb) Lipka M, Filipek R, Bochtler M Biochemistry. 2008

2007

The highest reflection intensity in a resolution shell Bochtler M, Chojnowski G Acta Crystallogr A. 2007 The statistics of the highest E value Chojnowski G, Bochtler M Acta Crystallogr A. 2007 Folds and activities of peptidoglycan amidases Firczuk M, Bochtler M FEMS Microbiol Rev. 2007 Publication Mutational analysis of peptidoglycan amidase MepA Firczuk M, Bochtler M. Biochemistry. 2007 Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically Kaus-Drobek M, Czapinska H, Sokołowska M, Tamulaitis G, Szczepanowski RH, Urbanke C, Siksnys V, Bochtler M Nucleic Acids Res. 2007 Restriction endonucleases that resemble a component of the bacterial DNA repair machinery Sokolowska M, Kaus-Drobek M, Czapinska H, Tamulaitis G, Siksnys V, Bochtler M Cell Mol Life Sci. 2007 Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA. Sokolowska M, Kaus-Drobek M, Czapinska H, Tamulaitis G, Szczepanowski RH, Urbanke C, Siksnys V, Bochtler M J Mol Biol. 2007 Nucleotide flipping by restriction enzymes analyzed by 2-aminopurine steady-state fluorescence Tamulaitis G, Zaremba M, Szczepanowski RH, Bochtler M, Siksnys V Nucleic Acids Res. 2007

2006

Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease Bochtler M, Szczepanowski RH, Tamulaitis G, Grazulis S, Czapinska H, Manakova E, Siksnys V EMBO J. 2006

2005

Characterization of the HslU chaperone affinity for HslV protease Azim MK, Goehring W, Song HK, Ramachandran R, Bochtler M, Goettig P Protein Sci. 2005 Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene Dandanell G,Szczepanowski RH, Kierdaszuk B, Shugar D, Bochtler M J Mol Biol. 2005 A comparison of staphostatin B with standard mechanism serine protease inhibitors Filipek R, Potempa J, Bochtler M J Biol Chem. 2005 Crystal structures of active LytM Firczuk M, Mucha A, Bochtler M J Mol Biol. 2005 Structure of the metal-independent restriction enzyme BfiI reveals fusion of a specific DNA-binding domain with a nonspecific nuclease. Grazulis S, Manakova E, Roessle M, Bochtler M, Tamulaitiene G, Huber R, Siksnys V Proc Natl Acad Sci U S A. 2005