Chemotherapy of HER2- and MDM2-Enriched Breast Cancer Subtypes Induces Homologous Recombination DNA Repair and Chemoresistance. Herok M, Wawrzynow B, Maluszek MJ, Olszewski MB, Zylicz A, Zylicz M. Cancers (Basel). 2021 HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells. Sojka DR, Gogler-Pigłowska A, Klarzyńska K, Klimczak M, Zylicz A, Głowala-Kosińska M, Krawczyk Z, Scieglinska D. Cancers (Basel). 2020 Zebrafish Microenvironment Elevates EMT and CSC-Like Phenotype of Engrafted Prostate Cancer Cells. Chen L, Olszewski MB, Kruithof-de MJ, Snaar-Jagalska BE. Cells. 2020 Heat shock proteins create a signature to predict the clinical outcome in breast cancer. Klimczak M, Biecek P, Zylicz A, Zylicz M. Sci Rep. . 2019 Function, evolution, and structure of J-domain proteins. Kampingaa HH et al. …. (Zylicz A, Zylicz M) Cell Stress Chaperones.. 2019 Diverse and cancer type‑specific roles of the p53 R248Q gain‑of‑function mutation in cancer migration and invasiveness. Olszewski MB, Pruszko M, Snaar-Jagalska E, Zylicz A, Zylicz M. Int. J. Oncol.. 2019 Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanism. Walerych D, Pruszko M, Zyla L, Wezyk M, Gaweda-Walerych K, Zylicz A. Oncotarget. 2018 Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages. Donzelli S, Milano E, Pruszko M, Sacconi A, Masciarelli S, Iosue I, Melucci E, Gallo E, Terrenato I, Mottolese M, Zylicz M, Zylicz A, Fazi F, Blandino G, Fontemaggi G. Breast Cancer Res.. 2018 Chaperoning the guardian of the genome. The two-faced role of molecular chaperones in p53 tumor suppressor action. Wawrzynow B, Zylicz A, Zylicz M. BBA-Rev Cancer. 2018 Novel role for the testis-enriched HSPA2 protein in regulating epidermal keratinocyte differentiation. Gogler-Pigłowska A, Klarzyńska K, Sojka DR, Habryka A, Głowala-Kosińska M, Herok M, Kryj M, Halczok M, Krawczyk Z, Scieglinska D. J Cell Physiol.. 2018 TRIM28 epigenetic corepressor is indispensable for stable induced pluripotent stem cell formation Klimczak M, Czerwińska P, Mazurek S, Sozańska B, Biecek P, Mackiewicz A, Wiznerowicz M Stem Cell Research. 2017 Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation Tracz-Gaszewska Z, Klimczak M, Biecek P, Herok M, Kosinski M, Olszewski MB, Czerwińska P, Wiech M, Wiznerowicz M, Zylicz A, Zylicz M, Wawrzynow B Oncotarget. 2017 The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1 Pruszko M, Milano E, Forcato M, Donzelli S, Ganci F, Di Agostino S, De Panfilis S, Fazi F, Bates DO, Bicciato S, Zylicz M, Zylicz A, Blandino G, Fontemaggi G EMBO Rep. 2017 Danio pręgowany jako organizm modelowy. Olszewski M, Pruszko M. Wszechświat. 2016 Białka z rodziny ID w inicjacji i progresji nowotworów (Białka z rodziny ID w inicjacji i progresji nowotworów). Pruszko M, Żylicz A. Postępy Biochemii. 2016 NeuroMorph: A Toolset for the Morphometric Analysis and Visualization of 3D Models Derived from Electron Microscopy Image Stacks. Jorstad A, Nigro B, Cali C, Wawrzyniak M, Fua P, Knott G. Neuroinformatics. 2015 Biologia syntetyczna: jak powstawało życie na Ziemi? Żylicz M. Nauka. 2013 Molecular Mechanism of Mutant p53 Stabilization: The Role of HSP70 and MDM2 Wiech M, Olszewski MB, Tracz-Gaszewska Z, Wawrzynow B, Zylicz M, Zylicz A PLoS One. 2012 The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities Hageman J, van Waarde MA, Zylicz A, Walerych D, Kampinga HH Biochem J. 2011 Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms Zubrienė A, Gutkowska M, Matulienė J, Chaleckis R, Michailovienė V, Voroncova A, Venclovas C, Zylicz A, Zylicz M, Matulis D Biophys Chem. 2010 The new platinum(IV) derivative LA-12 shows stronger inhibitory effect on Hsp90 function compared to cisplatin Kvardova V, Hrstka R, Walerych D, Muller P, Matoulkova E, Hruskova V, Stelclova D, Sova P, Vojtesek B Mol Cancer. 2010 Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology. Kirkegaard T, Roth AG, Petersen NH, Mahalka AK, Olsen OD, Moilanen I, Zylicz A, Knudsen J, Sandhoff K, Arenz C, Kinnunen PK, Nylandsted J, Jäättelä M Nature. 2010 Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo. Zurawska A, Urbanski J, Matuliene J, Baraniak J, Klejman MP, Filipek S, Matulis D, Bieganowski P Biochim Biophys Acta. 2010 ATP binding to Hsp90 is sufficient for effective chaperoning of p53 protein. Walerych D, Gutkowska M, Klejman MP, Wawrzynow B, Tracz Z, Wiech M, Zylicz M, Zylicz A J Biol Chem. 2010 Publication Mathematical modelling of the influence of heat shock proteins on cancer invasion of tissue. Szymańska Z, Urbański J, Marciniak-Czochra A. J Math Biol. 2009 Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions. Walerych D, Olszewski MB, Gutkowska M, Helwak A, Zylicz M, Zylicz A Oncogene. 2009 Cooperative regulation of the interferon regulatory factor-1 tumor suppressor protein by core components of the molecular chaperone machinery Narayan V, Eckert M, Zylicz A, Zylicz M, Ball KL J Biol Chem. 2009 A function for the RING finger domain in the allosteric control of MDM2 conformation and activity. Wawrzynow B, Pettersson S, Zylicz A, Bramham J, Worrall E, Hupp TR, Ball KL J Biol Chem. 2009 Fhit proteins can also recognize substrates other than dinucleoside polyphosphates. Guranowski A, Wojdyła AM, Pietrowska-Borek M, Bieganowski P, Khurs EN, Cliff MJ, Blackburn GM, Błaziak D, Stec WJ FEBS Lett. 2008 The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1. Sbroggiò M, Ferretti R, Percivalle E, Gutkowska M, Zylicz A, Michowski W, Kuznicki J, Accornero F, Pacchioni B, Lanfranchi G, Hamm J, Turco E, Silengo L, Tarone G, Brancaccio M. FEBS Lett. 2008