2019

Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7. Mohanraj K, Wasilewski M, Benincá C, Cysewski D, Poznanski J, Sakowska P, Bugajska Z, Deckers M, Dennerlein S, Fernandez-Vizarra E, Rehling P, Dadlez M, Zeviani M, Chacinska A. EMBO Mol Med.. 2019 Non-canonical translation initiation in yeast generates a cryptic pool of mitochondrial proteins. Monteuuis G, Miścicka A, Świrski M, Zenad L, Niemitalo O, Wrobel L, Alam J, Chacinska A, Kastaniotis AJ, Kufel J. Nucleic Acids Res.. 2019 Cytosolic translational responses differ under conditions of severe short-term and long-term mitochondrial stress. Samluk L, Urbanska M, Kisielewska K, Mohanraj K, Kim MJ, Machnicka K, Liszewska E, Jaworski J, Chacinska A. Mol Biol Cell.. 2019

2018

Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish. Sokol AM, Uszczynska-Ratajczak B, Collins MM, Bazala M, Topf U, Lundegaard PR, Sugunan S, Guenther S, Kuenne C, Graumann J, Chan SSL, Stainier DYR, Chacinska A. PLoS Genet.. 2018 Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins. Kowalski L, Bragoszewski P, Khmelinskii A, Glow E, Knop M, Chacinska A. BMC Biol. . 2018 Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species. Topf U, Suppanz I, Samluk L, Wrobel L, Böser A, Sakowska P, Knapp B, Pietrzyk MK, Chacinska A, Warscheid B. Nat Commun. . 2018

2017

Visualization of cytosolic ribosomes on the surface of mitochondria by electron cryo-tomography. Gold VA, Chroscicki P, Bragoszewski P, Chacinska A. EMBO Rep.. 2017 Cell biology: Sort and destroy Chacinska A. Nature. 2017 Control of mitochondrial biogenesis and function by the ubiquitin-proteasome system Bragoszewski P, Turek M, Chacinska A. Open Biol. 2017

2016

Protein trafficking at the crossroads to mitochondria Wasilewski M, Chojnacka K, Chacinska A Biochim Biophys Acta. 2016 Białka mitochondrialne – import, eksport, degradacja Wasilewski M, Chojnacka K, Chacinska A Postępy Biochemii. 2016 TIM29 is a subunit of the human carrier translocase required for protein transport Callegari S, Richter F, Chojnacka K, Jans DC, Lorenzi I, Pacheu-Grau D, Jakobs S, Lenz C, Urlaub H, Dudek J, Chacinska A, Rehling P FEBS Lett. 2016 Protein Import by the Mitochondrial Presequence Translocase in the Absence of a Membrane Potential Turakhiya U, von der Malsburg K, Gold VA, Guiard B, Chacinska A, van der Laan M, Ieva R J Mol Biol. 2016 The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly Wrobel L, Sokol AM, Chojnacka M, Chacinska A Sci Rep. 2016 Chatty Mitochondria: Keeping Balance in Cellular Protein Homeostasis Topf U, Wrobel L, Chacinska A Trends Cell Biol. 2016

2015

Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death Keatinge M, Bui H, Menke A, Chen YC, Sokol AM, Bai Q, Ellett F, Da Costa M, Burke D, Gegg M, Trollope L, Payne T, McTighe A, Mortiboys H, de Jager S, Nuthall H, Kuo MS, Fleming A, Schapira AH, Renshaw SA, Highley JR, Chacinska A, Panula P, Burton EA, O'Neill MJ, Bandmann O Hum Mol Genet. 2015 The oxidation status of Mic19 regulates MICOS assembly Sakowska P, Jans DC, Mohanraj K, Riedel D, Jakobs S, Chacinska A Mol Cell Biol. 2015 Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol Wrobel L, Topf U, Bragoszewski P , Wiese S, Sztolsztener ME , Oeljeklaus S, Varabyova A, Lirski M, Chroscicki P, Mroczek S, Januszewicz E, Dziembowski A, Koblowska M, Warscheid B, Chacinska A Nature. 2015 Retro-translocation of mitochondrial intermembrane space proteins Bragoszewski P, Wasilewski M, Sakowska P, Gornicka A, Böttinger L, Qiu J, Wiedemann N, Chacinska A Proc Natl Acad Sci U S A. 2015 Cox17 is an auxiliary factor involved in the control of the mitochondrial contact site and cristae organizing system Chojnacka M, Gornicka A, Oeljeklaus S, Warscheid B, Chacinska A J Biol Chem. 2015 Mitochondrial translocation of APE1 relies on the MIA pathway Barchiesi A, Wasilewski M, Chacinska A, Tell G, Vascotto C Nucleic Acids Res. 2015

2014

Mgr2 functions as lateral gatekeeper for preprotein sorting in the mitochondrial inner membrane Ieva R, Schrempp SG, Opaliński L Wollweber F, Höß P, Heißwolf AK, Gebert M, Zhang Y, Guiard B, Rospert S, Becker T, Chacinska A, Pfanner N, van der Laan M Mol Cell.. 2014 A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria Gornicka A, Bragoszewski P, Chroscicki P, Wenz LS, Schulz C, Rehling P, Chacinska A Mol Biol Cell. 2014 Presequence recognition by the tom40 channel contributes to precursor translocation into the mitochondrial matrix Melin J, Schulz C, Wrobel L, Bernhard O, Chacinska A, Jahn O, Schmidt B, Rehling P Mol Cell Biol. 2014 Mitochondrial protein translocases for survival and wellbeing Sokol AM, Sztolsztener ME, Wasilewski M, Heinz E, Chacinska A FEBS Lett. 2014 Uniform nomenclature for the mitochondrial contact site and cristae organizing system Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J J Cell Biol.. 2014

2013

Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation Qiu J, Wenz LS, Zerbes RM, Oeljeklaus S, Bohnert M, Stroud DA, Wirth C, Ellenrieder L, Thornton N, Kutik S, Wiese S, Schulze-Specking A, Zufall N, Chacinska A, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N, Wiedemann N, Becker T Cell. 2013 Mia40 and MINOS act in parallel with Ccs1 in the biogenesis of mitochondrial Sod1 Varabyova A, Topf U, Kwiatkowska P, Wrobel L, Kaus-Drobek M, Chacinska A FEBS J. 2013 The ubiquitin-proteasome system regulates mitochondrial intermembrane space proteins Bragoszewski P, Gornicka A, Sztolsztener ME, Chacinska A Mol Cell Biol. 2013 Mitochondrial protein import: Mia40 facilitates Tim22 translocation into the inner membrane of mitochondria Wrobel L, Trojanowska A, Sztolsztener ME, Chacinska A Mol Biol Cell. 2013