2026

Publication Etiology of TP53 mutated complex karyotype acute myeloid leukemia. Fedenko A, Czapinska H, Krämer A, Stölzel F, Bochtler T, Bochtler M. Leukemia. 2026

2025

Publication Unlocking the regulatory code of RNA: launching the Human RNome Project. International Human RNome Project Consortium (within Bujnicki JM) Genome Biol. 2025 Publication Introducing the "other" type of DNA methylation. Bochtler M. Sci Adv. 2025 Publication Activity and structure of human (d)CTP deaminase CDADC1. Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M. Proc Natl Acad Sci U S A. 2025 Publication How the technologies behind self-driving cars, social networks, ChatGPT, and DALL-E2 are changing structural biology. Bochtler M. Bioessays. 2025

2024

Publication Protein memory? Bochtler M. Bioessays. 2024 Publication Structural analysis of the BisI family of modification dependent restriction endonucleases. Szafran K, Rafalski D, Skowronek K, Wojciechowski M, Kazrani AA, Gilski M, Xu SY, Bochtler M. Nucleic Acids Res. 2024 Publication Cytosine analogues as DNA methyltransferase substrates. Wojciechowski M, Czapinska H, Krwawicz J, Rafalski D, Bochtler M. Nucleic Acids Res. 2024 Publication Characterization of winged helix domain fusion endonucleases as N6-methyladenine-dependent type IV restriction systems. Helbrecht I, Heiter D, Yang W, Vincze T, Hanneman A, Lutz T, Ettwiller L, Bochtler M, Xu SY. Front Microbiol. 2024 Publication RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases. Di Zhang D, Czapinska H, Bochtler M, Wlodawer A, Lubkowski J. Protein Sci. 2024 Publication X-rays, electrons, and neutrons as probes of atomic matter. Bochtler M. Structure. 2024

2023

Preprint Modification of DNA by a viral enzyme and charged tRNA. Silva RMB, Slyvka A, Lee Y-J, Guan C, Lund SR, Raleigh EA, Skowronek K, Bochtler M, Weigele PR. bioRxiv. 2023 Publication The Bacteroidetes Q-rule and glutaminyl cyclase activity increase the stability of extracytoplasmic proteins. Szczęśniak K, Veillard F, Scavenius C, Chudzik K, Ferenc K, Bochtler M, Potempa J, Mizgalska D. mBio.. 2023 Publication Bicarbonate Activation of the Monomeric Photosystem II-PsbS/Psb27 Complex. Fantuzzi A, Haniewicz P, Farci D, Loi MC, Park K, Büchel C, Bochtler M, Rutherford AW, Piano D. Plant Physiol.. 2023 Publication Clustered PHD domains in KMT2/MLL proteins are attracted by H3K4me3 and H3 acetylation-rich active promoters and enhancers. Stroynowska-Czerwinska AM, Klimczak M, Pastor M, Kazrani AA, Misztal K, Bochtler M. Cell Mol Life Sci. 2023

2022

Publication Competition between electrostatic interactions and halogen bonding in the protein–ligand system: structural and thermodynamic studies of 5,6-dibromobenzotriazole-hCK2α complexes. Winiewska‑Szajewska M, Czapinska H, Kaus‑Drobek M, Fricke A, Mieczkowska K, Dadlez M, Bochtler M, Poznański J. Sci Rep. 2022 Publication Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function. Ravichandran M, Rafalski D, Davies CI, Ortega-Recalde O, Nan X, Glanfield CR, Kotter A, Misztal K, Wang AH, Wojciechowski M, Rażew M, Mayyas IM, Kardailsky O, Schwartz U, Zembrzycki K, Morison IM, Helm M, Weichenhan D, Jurkowska RZ, Krueger F, Plass C, Zacharias M, Bochtler M, Hore TA, Jurkowski TP. Sci Adv. 2022 Publication Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish. Niescierowicz K#, Pryszcz L#, Navarrete C#, Tralle E#, Sulej A#, Abu Nahia K, Kasprzyk ME, Misztal K, Pateria A, Pakuła A, Bochtler M, Winata C. # Contributed equally Nat Commun. 2022 Publication The Nε-rule for serine, but not cysteine catalytic triads. Czapińska H, Bochtler M. Angew Chem Int Ed Engl. 2022

2021

Distinction between self and non-self in restriction modification: The mysterious case of type IIL enzymes. Bochtler M. Structure. 2021 Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2. Czapinska H, Winiewska-Szajewska M, Szymaniec-Rutkowska A, Piasecka A, Bochtler M, Poznański J. J Phys Chem B.. 2021 Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA. Pastor M, Czapinska H, Helbrecht I, Krakowska K, Lutz T, Xu S, Bochtler M. Nucleic Acids Res.. 2021 DNA adenine methylation in eukaryotes: Enzymatic mark or a form of DNA damage? Bochtler M, Fernandes H. BioEssays. 2021

2020

Reversal of nucleobase methylation by dioxygenases. Xu G-L, Bochtler M. Nat Chem Biol. 2020 Targeted RNA Knockdown by a Type III CRISPR-Cas Complex in Zebrafish. Fricke T, Smalakyte D, Lapinski M, Pateria A, Weige C, Pastor M, Kolano A, Winata C, Siksnys V, Tamulaitis G, Bochtler M. CRISPR J.. 2020 Protein Domain Guided Screen for Sequence Specific and Phosphorothioate-Dependent Restriction Endonucleases. Lutz T, Czapinska H, Fomenkov A, Potapov V, Heiter DF, Cao B, Dedon P, Bochtler M, Xu S. Front. Microbiol.. 2020 Restriction endonucleases that cleave RNA/DNAheteroduplexes bind dsDNA in A-like conformation. Kisiala M, Kowalska M, Pastor M, Korza HJ, Czapinska H, Bochtler M. Nucleic Acids Res.. 2020 In Vitro Directed Evolution of a Restriction Endonuclease With More Stringent Specificity. Skowronek KJ, Bochtler M. J Vis Exp . 2020 Arrhenius-law-governed homo- and heteroduplex dissociation. Bochtler M. Phys Rev E. 2020

2019

Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping. Slyvka A, Zagorskaitė E, Czapinska H, Sasnauskas G, Bochtler M. Nucleic Acids Res.. 2019