Publication Lower urinary tract symptoms in older adults as a manifestation of underlying geriatric conditions: results of a national population-based study PolSenior2. Kujawska-Danecka H, Mossakowska M, Chudek J, Hajduk A, Wieczorowska-Tobis K, Chmielewski M, Gryglewska B. Pol Arch Intern Med. 2025 Preprint Mitochondrial redox homeostasis links organellar stress surveillance to germline and somatic integrity in Caenorhabditis elegans. Valenzuela-Villatoro M, de la Cruz-Ruiz P, Guerrero-Gomez D, Gomez-Orte E, Schiavi A, Maglioni S, Montero M, Fonteriz R, Casas-Martinez JC, Briand N, Xu J, Rodriguez-Palero MJ, Artal-Sanz M, Olek K, Polaczyk J, Turek M, Pokrzywa W, Xu S, Irazoqui J, McDonagh B, Alvarez J, Olmedo M, Ventura N, Cabello J, Miranda-Vizuete A. bioRxiv . 2025 Publication Evaluation of single-template ligand-based methods for the discovery of small-molecule nucleic acid binders. Bajusz D, Rácz A, Bujnicki JM, Stefaniak F. Brief Bioinform. 2025 Publication Astrocytes distress triggers brain pathology through induction of δ secretase in a murine model of Alzheimer's disease. Schmidt V, Ziemlinska E, Obrebski T, Gomes JP, Zurawska-Plaksej E, Cendrowski J, Palmfeldt J, Hempstead BL, Willnow TE, Malik AR. Nat Commun. 2025 Publication Zebrafish as a model for Catel-Manzke syndrome-identification and characterization of the zebrafish TGDS ortholog. Coppola MR, Bellitto D, Asgari E, Bazzurro V, Casucci G, Piacente F, Bozzo M, Ceresa D, Parisi C, Winata C, Candiani S, Tonetti M. FEBS J. 2025 Publication Unlocking the regulatory code of RNA: launching the Human RNome Project. International Human RNome Project Consortium (within Bujnicki JM) Genome Biol. 2025 Publication Exploring GNRA tetraloop-like motifs in nucleic acid 3D structures. Bujnicki JM, Baulin EF. Sci Rep. 2025 Publication Molecular cargo of small EVs from NSCLC patient BALF and plasma: unveiling their role in airway inflammation and immune regulation in a novel human 3D bronchial model. Dlugolecka M, Szymanski J, Zareba L, Soroczynska K, Homoncik Z, Polubiec-Kownacka M, Frankiewicz E, Wierzbicka D, Thetchinamoorthy K, Domagala-Kulawik J, Czystowska-Kuzmicz M. Cell Commun Signal. 2025 Preprint A dosage-sensitive ALLO-1 network coordinates mitochondrial quality control to enable functional recovery of structurally compromised muscle. Sarkar A, Biriczova L, Szulc NA, Thapa P, Serwa R, Pokrzywa W. bioRxiv. 2025 Publication Epigenomics and transcriptomics profiles of developing zebrafish heart cells. Chahal G, Eichenlaub MP, Tondl M, Pawlak M, Mohenska M, Grimm L, Bottrell L, Drvodelic M, Alaei S, Hallab J, Waylen LN, Polo JM, Blanpain C, Palpant N, Rossello FJ, Änkö ML, Currie PD, Hogan BM, Winata C, Salimova E, Nim HT, Ramialison M. Sci Data. 2025 Publication Trifluoperazine, an Antipsychotic Drug, Inhibits Viability of Cells Derived From SEGA and Cortical Tubers Cultured In Vitro. Urbanska M, Sadowski K, Stawikowska A, Liszewska E, Mlostek M, Grajkowska W, Kotulska K. J Neurochem. 2025 Publication West Nile virus vaccine candidates attenuated by dinucleotide enrichment are immunogenic and protective against lethal infection. Le NPK, Singh PP, Trus I, Karniychuk U. PLoS Pathog. 2025 Preprint CHIP, VCP, and Nucleolar Gatekeepers Remodel the Nucleolus into a Stress-Responsive Proteostasis Hub. Piechota M, Biriczova L, Kowalski K, Garcia FA, Lesniczak-Staszak M, Szulc NA, Szaflarski W, Sawarkar R, Pokrzywa W. bioRxiv. 2025 Publication Role of store-operated Ca2+ entry and STIM2 in retinal neurodegeneration during glaucoma. Baranykova S. Front Aging Neurosci. 2025 Publication Polyadenylation landscape of in vivo long-term potentiation in the rat brain. Gumińska N, Pauzin FP, Kuźniewska B, Miłek J, Wardaszka-Pianka P, Krawczyk PS, Mroczek S, Jeleń S, Pagenhart PU, Bramham CR, Dziembowski A, Dziembowska M. RNA. 2025 Preprint Nutritional iron deficiency elicits profound rewiring of red pulp macrophage functions via high FPN and SYK-mediated signaling. Mandal PK, Chouhan K, Slusarczyk P, Mahadeva R, Zurawska G, Niklewicz M, Jończy A, Lenartowicz M, Pokrzywa W, Meynard D, Nemeth E, Mleczko-Sanecka K. bioRxiv. 2025 Publication Translon: a single term for translated regions. Świrski MI et al (with Bujnicki JM) Nat Methods. 2025 Publication Excretory gland cell and NSPC genes in C. elegans: investigating their physiological roles. Mackiewicz Z, Liudkovska V, Dziembowski A. Genetics. 2025 Publication Tissue-specific consequences of tag fusions on protein expression in transgenic mice. Taylor GCA, Macdonald L, Szulc NA, Gudauskaite E, Hernandez Moran B, Brisbane JM, Donald M, Taylor E, Zheng D, Gu B, Mill P, Yeyati PL, Pokrzywa W, Ribeiro de Almeida C, Wood AJ. PLoS Genet. 2025 Publication Genome-wide in vivo and ex vivo mapping of R-loops using engineered N-terminal hybrid-binding domain of RNase H3 (enDR3). Jedynak-Slyvka M, Kaczmarska Z, Graczyk D, Jurkiewicz A, Figiel M, Borowski LS, Szczesny RJ, Nowotny M. Nucleic Acids Res. 2025 Publication Modeling flexible RNA 3D structures and RNA-protein complexes. Loureiro RJ, Maiti S, Mondal K, Mukherjee S, Bujnicki JM. Curr Opin Struct Biol. 2025 Publication ARTEM: a method for RNA and DNA tertiary motif identification with backbone permutations. Baulin EF, Bohdan DR, Kowalski D, Serwatka M, Świerczyńska J, Żyra Z, Bujnicki JM. Genome Biol. 2025 Publication Chemical circularization of in vitro transcribed RNA for exploring circular mRNA design. Wasinska-Kalwa M, Mamot A, Czubak K, Frankowska K, Rajkiewicz AA, Spiewla T, Warminski M, Pilch Z, Szulc-Gasiorowska M, Siekan K, Dziembowski A, Nowis D, Golab J, Kowalska J, Jemielity J. Nat Commun. 2025 Preprint 5′-triphosphate guanosine RNAs recruit GTP-binding proteins to suppress RIG-I/IFN type I signaling. Szymanski J, Wolczyk M, Trus I, Naz Z, Idlin N, Jackiewicz J, Nowak E, Wuebben C, Hartmann G, Rappsilber J, Michlewski G. bioRxiv. 2025 Publication Quantitative insights into protein turnover and ubiquitination with HiBiT and NanoBRET. Piechota M, Pokrzywa W. Methods in Enzymology. 2025 Publication DEGRONOPEDIA: A practical guide to identifying and targeting protein degrons. Szulc NA, Pokrzywa W. Methods in Enzymology. 2025 Publication Structure of fungal tRNA ligase Trl1 with RNA reveals conserved substrate-binding principles. Köhler S, Kopp J, Maiti S, Bujnicki JM, Peschek J. Nat Struct Mol Biol. 2025 Preprint Structural insights into DNA annealing and recombination by herpesviral DNA-binding proteins ICP8 and BALF2. Apte GR, Patra S, Czarnocki-Cieciura M, Jabeen A,
Jackiewicz J, Poznański J, Nowotny M, Figiel M. bioRxiv. 2025 Publication The expanding repertoire of ESCRT functions in cell biology and disease. Hurley JH, Coyne AN, Miączyńska M, Stenmark H. Nature. 2025 Publication Transferrin receptor controls both autophagosome formation and closure via phosphatidylinositol 3-phosphate synthesis. Puri C, Park SJ, Wrobel L, Rubinsztein DC. Dev Cell. 2025